keyword
MENU ▼
Read by QxMD icon Read
search

Ketogenic diet performance

keyword
https://www.readbyqxmd.com/read/27836684/ketogenic-diets-improve-behaviors-associated-with-autism-spectrum-disorder-in-a-sex-specific-manner-in-the-el-mouse
#1
David N Ruskin, Jessica A Fortin, Subrina N Bisnauth, Susan A Masino
The core symptoms of autism spectrum disorder are poorly treated with current medications. Symptoms of autism spectrum disorder are frequently comorbid with a diagnosis of epilepsy and vice versa. Medically-supervised ketogenic diets are remarkably effective nonpharmacological treatments for epilepsy, even in drug-refractory cases. There is accumulating evidence that supports the efficacy of ketogenic diets in treating the core symptoms of autism spectrum disorders in animal models as well as limited reports of benefits in patients...
January 1, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/27822291/monitoring-for-compliance-with-a-ketogenic-diet-what-is-the-best-time-of-day-to-test-for-urinary-ketosis
#2
Paul Urbain, Hartmut Bertz
BACKGROUND: The ketogenic diet (KD) is a very low-carbohydrate, high-fat and adequate-protein diet with no calorie limit that induces a metabolic condition called "physiological ketosis". It was first introduced to treat epilepsy in the 1920s and has become quite popular recently as weight-loss and performance-enhancing diet. Its therapeutic use in a range of diseases is under investigation. During KD interventions people are supposed to monitor compliance with the dietary regimen by daily urine testing for ketosis...
2016: Nutrition & Metabolism
https://www.readbyqxmd.com/read/27777605/metabolic-response-of-glioblastoma-cells-associated-with-glucose-withdrawal-and-pyruvate-substitution-as-revealed-by-gc-ms
#3
Henry Oppermann, Yonghong Ding, Jeevan Sharma, Mandy Berndt Paetz, Jürgen Meixensberger, Frank Gaunitz, Claudia Birkemeyer
BACKGROUND: Tumor cells are highly dependent on glucose even in the presence of oxygen. This concept called the Warburg effect is a hallmark of cancer and strategies are considered to therapeutically exploit the phenomenon such as ketogenic diets. The success of such strategies is dependent on a profound understanding of tumor cell metabolism. With new techniques it is now possible to thoroughly analyze the metabolic responses to the withdrawal of substrates and their substitution by others...
2016: Nutrition & Metabolism
https://www.readbyqxmd.com/read/27754807/body-composition-changes-after-very-low-calorie-ketogenic-diet-in-obesity-evaluated-by-three-standardized-methods
#4
Diego Gomez-Arbelaez, Diego Bellido, Ana I Castro, Lucia Ordoñez-Mayan, Jose Carreira, Cristobal Galban, Miguel A Martinez-Olmos, Ana B Crujeiras, Ignacio Sajoux, Felipe F Casanueva
CONTEXT: A common concern when using low-calorie diets as a treatment for obesity is the reduction in fat-free mass, mostly muscular mass that occurs together with the fat mass loss, and the best methodologies to evaluate body composition changes. OBJECTIVE: To evaluate the very low-calorie-ketogenic (VLCK) diet-induced changes in body composition of obese patients and to compare three different methodologies employed to evaluate that changes. DESIGN: Twenty obese patients followed a VLCK diet for 4 months...
October 18, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27699772/diet-and-headache-part-2
#5
Vincent T Martin, Brinder Vij
BACKGROUND: Comprehensive diets do not require the exclusion of a specific provocative food or ingredient, but regulate the quantities of core components of foods such as vitamins, ions, proteins, carbohydrates, and fats. OBJECTIVES: To review the evidence supporting the use of comprehensive diets in the prevention of migraine and other headache disorders and to discuss the mechanisms through which food, and ingredients within foods and beverages might trigger attacks of headache METHODS: This represents Part 2 of a narrative review of the role of diet in the prevention of migraine and other headache disorders...
October 2016: Headache
https://www.readbyqxmd.com/read/27596103/current-treatment-options-for-early-onset-pediatric-epileptic-encephalopathies
#6
REVIEW
Rolla Shbarou
The management of early-onset, genetically determined epilepsies is often challenging. First-line anti-epileptic drugs (AEDs) often include phenobarbital, phenytoin, oxcarbazepine, carbamazepine, clonazepam, levetiracetam, and valproic acid. Combinations of medications are used in these patients with often intractable seizures, and they include topiramate, clobazam, felbamate, lacosamide, lamotrigine, rufinamide, vigabatrin, ACTH, oral steroids, and the ketogenic diet. Vagus nerve stimulator therapy offers some relief in selected patients...
October 2016: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/27591681/cost-utility-analysis-of-competing-treatment-strategies-for-drug-resistant-epilepsy-in-children-with-tuberous-sclerosis-complex
#7
Aria Fallah, Alexander G Weil, Shelly Wang, Evan Lewis, Christine B Baca, Gary W Mathern
BACKGROUND: The management of drug-resistant epilepsy in children with Tuberous Sclerosis Complex (TSC) is challenging because of the multitude of treatment options, wide range of associated costs, and uncertainty of seizure outcomes. The most cost-effective approach for children whose epilepsy has failed to improve with first-line medical therapy is uncertain. METHODS: A review of MEDLINE from 1990 to 2015 was conducted. A cost-utility analysis, from a third-party payer perspective, was performed for children with drug-resistant epilepsy that had failed to improve with 2 antiseizure drugs (ASDs) and that was amenable to resective epilepsy surgery, across a time-horizon of 5years...
October 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/27553113/a-practical-approach-to-ketogenic-diet-in-the-pediatric-intensive-care-unit-for-super-refractory-status-epilepticus
#8
Raquel Farias-Moeller, Luca Bartolini, Archana Pasupuleti, R D Brittany Cines, Amy Kao, Jessica L Carpenter
BACKGROUND: Super-refractory status epilepticus (SRSE) ensues when there is no improvement of seizure control in response to anesthetic therapy or seizure recurrence after reduction of anesthetic agents. There is no consensus on standard of care for SRSE. Ketogenic diet (KD) has reported success, but technical challenges exist including inability to feed patients, concomitant steroid use, acidotic states, and lack of dieticians with experience. The optimal protocol for KD is yet to be determined...
August 23, 2016: Neurocritical Care
https://www.readbyqxmd.com/read/27525031/modified-atkins-diet-in-advanced-malignancies-final-results-of-a-safety-and-feasibility-trial-within-the-veterans-affairs-pittsburgh-healthcare-system
#9
Jocelyn L Tan-Shalaby, Jennifer Carrick, Krystal Edinger, Dana Genovese, Andrew D Liman, Vida A Passero, Rashmikant B Shah
BACKGROUND: Dysfunctional mitochondrial processes limit malignant cells ability to use energy from fatty acids and ketones. Animal studies using ketogenic diets for cancer show encouraging results. We tested the diet's safety and feasibility in cancer patients across a broad variety of solid tumors. METHODS: We recruited 17 advanced cancer patients who were not on chemotherapy. They consumed 20 to 40 g of carbohydrates daily with evaluations performed weekly until week 4, then every 4 weeks until 16 weeks...
2016: Nutrition & Metabolism
https://www.readbyqxmd.com/read/27475280/ketogenic-diet-treatment-for-pediatric-super-refractory-status-epilepticus
#10
Brian Appavu, Lisa Vanatta, John Condie, John F Kerrigan, Randa Jarrar
PURPOSE: We aimed to study whether ketogenic diet (KD) therapy leads to resolution of super-refractory status epilepticus in pediatric patients without significant harm. METHOD: A retrospective review was performed at Phoenix Children's Hospital on patients with super-refractory status epilepticus undergoing ketogenic diet therapy from 2011 to 2015. RESULTS: Ten children with super-refractory status epilepticus, ages 2-16 years, were identified...
October 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27430501/ketone-bodies-and-exercise-performance-the-next-magic-bullet-or-merely-hype
#11
Philippe J M Pinckaers, Tyler A Churchward-Venne, David Bailey, Luc J C van Loon
Elite athletes and coaches are in a constant search for training methods and nutritional strategies to support training and recovery efforts that may ultimately maximize athletes' performance. Recently, there has been a re-emerging interest in the role of ketone bodies in exercise metabolism, with considerable media speculation about ketone body supplements being routinely used by professional cyclists. Ketone bodies can serve as an important energy substrate under certain conditions, such as starvation, and can modulate carbohydrate and lipid metabolism...
July 18, 2016: Sports Medicine
https://www.readbyqxmd.com/read/27265003/evaluation-of-non-coding-variation-in-glut1-deficiency
#12
Yu-Chi Liu, Jia Wei Audrey Lee, Susannah T Bellows, John A Damiano, Saul A Mullen, Samuel F Berkovic, Melanie Bahlo, Ingrid E Scheffer, Michael S Hildebrand
AIM: Loss-of-function mutations in SLC2A1, encoding glucose transporter-1 (GLUT-1), lead to dysfunction of glucose transport across the blood-brain barrier. Ten percent of cases with hypoglycorrhachia (fasting cerebrospinal fluid [CSF] glucose <2.2mmol/L) do not have mutations. We hypothesized that GLUT1 deficiency could be due to non-coding SLC2A1 variants. METHOD: We performed whole exome sequencing of one proband with a GLUT1 phenotype and hypoglycorrhachia negative for SLC2A1 sequencing and copy number variants...
December 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/27206235/cognitive-and-behavioral-impact-of-the-ketogenic-diet-in-children-and-adolescents-with-refractory-epilepsy-a-randomized-controlled-trial
#13
Dominique M IJff, Debby Postulart, Danielle A J E Lambrechts, Marian H J M Majoie, Reina J A de Kinderen, Jos G M Hendriksen, Silvia M A A Evers, Albert P Aldenkamp
PURPOSE: The ketogenic diet (KD) is increasingly used for the treatment of refractory epilepsy in childhood because of the beneficial effect on seizure reduction. The aim of the current study was to objectively assess cognition and aspects of behavior during the first 4months of a randomized controlled study in children and adolescents. METHODS: Participants from a tertiary epilepsy center were randomized to a KD group (intervention) or a care-as-usual (CAU) group (control)...
July 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/27147436/long-term-effects-of-ketogenic-diet-on-subsequent-seizure-induced-brain-injury-during-early-adulthood-relationship-of-seizure-thresholds-to-zinc-transporter-related-gene-expressions
#14
Tian Tian, Li-Li Li, Shu-Qi Zhang, Hong Ni
The divalent cation zinc is associated with cortical plasticity. However, the mechanism of zinc in the pathophysiology of cortical injury-associated neurobehavioral damage following neonatal seizures is uncertain. We have previously shown upregulated expression of ZnT-3; MT-3 in hippocampus of neonatal rats submitted to flurothyl-induced recurrent seizures, which was restored by pretreatment with ketogenic diet (KD). In this study, utilizing a novel "twist" seizure model by coupling early-life flurothyl-induced seizures with later exposure to penicillin, we further investigated the long-term effects of KD on cortical expression of zinc homeostasis-related genes in a systemic scale...
May 5, 2016: Biological Trace Element Research
https://www.readbyqxmd.com/read/27072799/gnao1-encephalopathy-further-delineation-of-a-severe-neurodevelopmental-syndrome-affecting-females
#15
Anna Marcé-Grau, James Dalton, Javier López-Pisón, María Concepción García-Jiménez, Lorena Monge-Galindo, Ester Cuenca-León, Jesús Giraldo, Alfons Macaya
BACKGROUND: De novo heterozygous mutations in the GNAO1 gene, encoding the Gα o subunit of G-proteins, are the cause of a severe neurodevelopmental disorder, featuring early infantile seizures, profound cognitive dysfunction and, occasionally, movement disorder (early infantile epileptic encephalopathy-17). METHODS: We report a further case of this association in a 20 month-old Spanish girl with neonatal-onset refractory seizures, progressive microcephaly, oral-lingual dyskinesia and nearly absent psychomotor development...
2016: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/27061881/the-effects-of-ketogenic-diet-on-the-th17-treg-cells-imbalance-in-patients-with-intractable-childhood-epilepsy
#16
Fen-Fen Ni, Cheng-Rong Li, Jian-Xiang Liao, Guo-Bing Wang, Su-Fang Lin, Yu Xia, Jia-Lun Wen
PURPOSE: The ketogenic diet (KD) is an effective treatment for intractable epilepsy (IE), however the therapeutic mechanism is still unclear. This study was designed to investigate T helper type 17/regulatory T cell (Th17/Treg) levels in children with IE and age-matched healthy controls following KD. METHOD: Circulating levels of Th17/Treg cells were analyzed by flow cytometry. Plasma concentration of interleukin (IL)-17 was measured by cytometric bead array assay...
May 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27060389/establishing-an-adult-epilepsy-diet-center-experience-efficacy-and-challenges
#17
Mackenzie C Cervenka, Bobbie J Henry, Elizabeth A Felton, Katlyn Patton, Eric H Kossoff
OBJECTIVES: Over 250 medical centers worldwide offer ketogenic diets to children with epilepsy; however, access to these therapies has been extremely limited for adults until recent years. We examine our 5-year experience creating and implementing a dedicated Adult Epilepsy Diet Center designed to provide adults with epilepsy access to ketogenic diets. MATERIAL AND METHODS: Outpatients seen at the Johns Hopkins Adult Epilepsy Diet Center from August 2010 thru September 2015 age 18years and older were enrolled in a prospective open-label observational study...
May 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/27043293/the-impact-of-3-1-ketogenic-diet-on-cardiac-repolarization-changes-in-children-with-refractory-seizures-a-prospective-follow-up-study
#18
Rahmi Özdemir, Orkide Güzel, Mehmet Küçük, Cem Karadeniz, Ünsal Yılmaz, Tansel Calik, Timur Meşe
Background The association between ketogenic diet (KD) and prolonged QT interval, life-threatening ventricular arrhythmias, and sudden death is controversial. Aim We aimed to prospectively evaluate the effect of KD on electrocardiography (ECG) measures in children with refractory epilepsy. Method A total of 70 children with drug-resistant epilepsy who received a KD for at least 12 months were included in the study. The standard 12-lead electrocardiography was performed in all patients before the beginning and in the 12th month of KD...
June 2016: Neuropediatrics
https://www.readbyqxmd.com/read/27031732/partial-amelioration-of-peripheral-and-central-symptoms-of-huntington-s-disease-via-modulation-of-lipid-metabolism
#19
Jane Y Chen, Conny Tran, Lin Hwang, Gang Deng, Michael E Jung, Kym F Faull, Michael S Levine, Carlos Cepeda
BACKGROUND: Huntington's disease (HD) is a fatal, inherited neurodegenerative disorder characterized by uncontrollable dance-like movements, as well as cognitive deficits and mood changes. A feature of HD is a metabolic disturbance that precedes neurological symptoms. In addition, brain cholesterol synthesis is significantly reduced, which could hamper synaptic transmission. OBJECTIVE: Alterations in lipid metabolism as a potential target for therapeutic intervention in the R6/2 mouse model of HD were examined...
2016: Journal of Huntington's Disease
https://www.readbyqxmd.com/read/26998986/-management-of-pediatric-status-epilepticus
#20
Carmen Paz Vargas L, Ximena Varela E, Karin Kleinsteuber S, Rocío Cortés Z, María de Los Ángeles Avaria B
Pediatric Status Epilepticus (SE) is an emergency situation with high morbidity and mortality that requires early and aggressive management. The minimum time criterion to define SE was reduced from 30 to 5 minutes, defined as continuous seizure activity or rapidly recurrent seizures without resumption of consciousness for more than 5 minutes. This definition considers that seizures that persist for > 5 minutes are likely to do so for more than 30 min. Those that persist for more than 30 minutes are more difficult to treat...
January 2016: Revista Médica de Chile
keyword
keyword
26801
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"