keyword
https://read.qxmd.com/read/38505743/a-randomized-feasibility-trial-of-the-modified-atkins-diet-in-older-adults-with-mild-cognitive-impairment-due-to-alzheimer-s-disease
#1
JOURNAL ARTICLE
Alison Buchholz, Pragney Deme, Joshua F Betz, Jason Brandt, Norman Haughey, Mackenzie C Cervenka
BACKGROUND: Alzheimer's disease (AD) is increasing in prevalence, but effective treatments for its cognitive impairment remain severely limited. This study investigates the impact of ketone body production through dietary manipulation on memory in persons with mild cognitive impairment due to early AD and explores potential mechanisms of action. METHODS: We conducted a 12-week, parallel-group, controlled feasibility trial of a ketogenic diet, the modified Atkins diet (MAD), compared to a control diet in patients with cognitive impairments attributed to AD...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38485731/ketogenic-diets-are-not-beneficial-for-athletic-performance-response-to-noakes
#2
JOURNAL ARTICLE
Louise M Burke, Jamie Whitfield
No abstract text is available yet for this article.
April 1, 2024: Medicine and Science in Sports and Exercise
https://read.qxmd.com/read/38460051/effect-of-social-media-on-diet-lifestyle-and-performance-of-athletes-a-review-of-current-evidence
#3
REVIEW
Santanu Nath, Sangita Bhattacharya, Vani Bhushanam Golla, Rajesh Kumar
PURPOSE OF REVIEW: Social media (SM) plays an important role in providing diet and health advice to athletes, but it also carries with it a risk of credibility in the information sought for and received. The objective of this review is to assess the knowledge gap on how SM influences dietary and lifestyle practices in athletes. RECENT FINDINGS: For this, relevant literature was searched in three leading databases with appropriate keywords, which were subjected to proper scrutiny that led to inclusion of 22 articles (original research papers, reviews, viewpoints, and commentaries)...
March 9, 2024: Current Nutrition Reports
https://read.qxmd.com/read/38455178/the-impact-of-ketogenic-diet-on-some-metabolic-and-non-metabolic-diseases-evidence-from-human-and-animal-model-experiments
#4
REVIEW
Yaseen Galali, Salih M S Zebari, Ahmed Aj Jabbar, Holem Hashm Balaky, Bashdar Abuzed Sadee, Hamed Hassanzadeh
The ketogenic diet (KD) is recognized as minimum carbohydrate and maximum fat intakes, which leads to ketosis stimulation, a state that is thought to metabolize fat more than carbohydrates for energy supply. KD has gained more interest in recent years and is for many purposes, including weight loss and managing serious diseases like type 2 diabetes. On the other hand, many believe that KD has safety issues and are uncertain about the health drawbacks. Thus, the outcomes of the effect of KD on metabolic and non-metabolic disease remain disputable...
March 2024: Food Science & Nutrition
https://read.qxmd.com/read/38428587/effectiveness-of-high-fat-and-high-carbohydrate-diets-on-body-composition-and-maximal-strength-after-15-weeks-of-resistance-training
#5
JOURNAL ARTICLE
Marek Kruszewski, Artur Kruszewski, Rafał Tabęcki, Stanisław Kuźmicki, Krzysztof Stec, Tadeusz Ambroży, Maksim Olegovich Aksenov, Maciej Merchelski, Tomasz Danielik
PURPOSE: The aim of this study was to compare High Carbohydrates Low Fat (HCLF) and Low Carbohydrate High Fat (LCHF) diets in terms of changes in body composition and maximal strength. PATIENTS/METHODS: The study involved 48 men aged 25 ± 2.5, divided into two groups, one of which (n = 23) was following the LCHF diet and the other (n = 25) the HCLF diet. Both groups performed the same resistance training protocol for 15 weeks...
February 28, 2024: Advances in Medical Sciences
https://read.qxmd.com/read/38424459/assessment-of-a-one-week-ketogenic-diet-on-brain-glycolytic-metabolism-and-on-the-status-epilepticus-stage-of-a-lithium-pilocarpine-rat-model
#6
JOURNAL ARTICLE
Matthieu Doyen, Clémentine Lambert, Emilie Roeder, Henri Boutley, Bailiang Chen, Julien Pierson, Antoine Verger, Emmanuel Raffo, Gilles Karcher, Pierre-Yves Marie, Fatiha Maskali
The ketogenic diet (KD) has been shown to be effective in refractory epilepsy after long-term administration. However, its interference with short-term brain metabolism and its involvement in the early process leading to epilepsy remain poorly understood. This study aimed to assess the effect of a short-term ketogenic diet on cerebral glucose metabolic changes, before and after status epilepticus (SE) in rats, by using [18 F]-FDG PET. Thirty-nine rats were subjected to a one-week KD (KD-rats, n = 24) or to a standard diet (SD-rats, n = 15) before the induction of a status epilepticus (SE) by lithium-pilocarpine administrations...
March 1, 2024: Scientific Reports
https://read.qxmd.com/read/38422595/the-efficacy-of-low-glycemic-index-diet-on-seizure-frequency-in-pediatric-patients-with-epilepsy-a-systematic-review-and-meta-analysis
#7
REVIEW
Pejman Rohani, Reza Shervin Badv, Mohammad Hassan Sohouli, Nathalia Sernizon Guimarães
BACKGROUND: Despite extensive research examining the effect of a low glycemic index (LGI) diet on the frequency of seizures in patients with epilepsy, the findings are inconclusive. Hence, we performed a systematic review and meta-analysis in order to clarify the potential effect of a low glycemic index (LGI) diet on the frequency of seizures in children. METHODS: A systematic review and meta-analysis written in accordance with the PRISMA checklist was realized using a comprehensive systematic search in four electronic databases until October 2023 without time or language restrictions...
February 21, 2024: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/38410637/ketogenic-diet-reduces-a-neurobiological-craving-signature-in-inpatients-with-alcohol-use-disorder
#8
JOURNAL ARTICLE
Corinde E Wiers, Peter Manza, Gene-Jack Wang, Nora D Volkow
BACKGROUND AND AIMS: Increasing evidence suggests that a ketogenic (high-fat, low-carbohydrate) diet (KD) intervention reduces alcohol withdrawal severity and alcohol craving in individuals with alcohol use disorder (AUD) by shifting brain energetics from glucose to ketones. We hypothesized that the KD would reduce a neurobiological craving signature when individuals undergoing alcohol detoxification treatment were exposed to alcohol cues. METHODS: We performed a secondary analysis of functional magnetic resonance data of 33 adults with an AUD who were randomized to a KD ( n  = 19) or a standard American diet (SA; n  = 14) and underwent 3 weeks of inpatient alcohol detoxification treatment...
2024: Frontiers in Nutrition
https://read.qxmd.com/read/38402708/efficacy-of-daily-versus-intermittent-low-glycemic-index-therapy-diet-in-children-with-drug-resistant-epilepsy-a-randomized-controlled-trial
#9
JOURNAL ARTICLE
Prateek Kumar Panda, Biswaroop Chakrabarty, Prashant Jauhari, Indar Kumar Sharawat, Anuja Agarwal, Vandana Jain, Ravindra M Pandey, Sheffali Gulati
INTRODUCTION: The predominant reason for the discontinuation of low glycemic index therapy (LGIT) in children with epilepsy is the dietary restrictions imposed therein. This trial intended to compare the efficacy of daily and intermittent LGIT in children with drug-resistant epilepsy (DRE). METHODS: This study was performed between February 2018 and January 2019 to compare the efficacy of daily and intermittent LGIT in children aged 1-15 years with DRE following 24 weeks of dietary therapy...
February 15, 2024: Epilepsy Research
https://read.qxmd.com/read/38389795/ketogenic-diet-and-behavior-insights-from-experimental-studies
#10
REVIEW
Konstancja Grabowska, Mateusz Grabowski, Marta Przybyła, Natalia Pondel, Jarosław J Barski, Marta Nowacka-Chmielewska, Daniela Liśkiewicz
As a journal page for full details. The ketogenic diet (KD) has been established as a treatment for epilepsy, but more recently it has been explored as an alternative or add-on therapy for many other diseases ranging from weight loss to neurological disorders. Animal models are widely used in studies investigating the therapeutic effects of the KD as well as underlying mechanisms. Especially in the context of neurological, psychiatric, and neurodevelopmental disorders essential endpoints are assessed by behavioral and motor tests...
2024: Frontiers in Nutrition
https://read.qxmd.com/read/38354549/efficacy-of-felbamate-in-a-cohort-of-patients-with-epilepsy-with-myoclonic-atonic-seizures-emats
#11
JOURNAL ARTICLE
Laurel Reed, Michael Ciliberto, Susan L Fong, Katherine Nickels, Eric Kossoff, Elaine Wirrell, Charuta Joshi
Epilepsy with myoclonic atonic seizures (EMAtS) is a rare childhood onset developmental and epileptic encephalopathy which is frequently refractory to medical therapy. The optimal antiseizure medication remains unknown. This study reports the efficacy of felbamate in children with EMAtS. Six large pediatric epilepsy centers performed a retrospective chart review on patients diagnosed with EMAtS at their institutions and collected data on felbamate usage and efficacy. Responders were classified as patients who had a 50% or greater reduction in seizures with a given therapy...
February 2, 2024: Epilepsy Research
https://read.qxmd.com/read/38297470/impact-of-the-ketogenic-diet-on-body-fat-muscle-mass-and-exercise-performance-a-review
#12
JOURNAL ARTICLE
Nana Chung
PURPOSE: The purpose of this review was to investigate the effects of the ketogenic diet (KD), on body fat, muscle mass, and exercise performance. As the KD is a subject of ongoing debate, we also present the existing evidence regarding its potential benefits in the aforementioned areas of body fat, muscle mass, and exercise performance. METHODS: A literature search was conducted using the keywords "ketogenic diet, low-carbohydrate diet, high-fat diet, body fat, muscle mass, and exercise performance" in PubMed, Web of Science, and Google Scholar...
December 2023: Physical activity and nutrition
https://read.qxmd.com/read/38291301/differential-peripheral-immune-signatures-elicited-by-vegan-versus-ketogenic-diets-in-humans
#13
JOURNAL ARTICLE
Verena M Link, Poorani Subramanian, Foo Cheung, Kyu Lee Han, Apollo Stacy, Liang Chi, Brian A Sellers, Galina Koroleva, Amber B Courville, Shreni Mistry, Andrew Burns, Richard Apps, Kevin D Hall, Yasmine Belkaid
Nutrition has broad impacts on all physiological processes. However, how nutrition affects human immunity remains largely unknown. Here we explored the impact of a dietary intervention on both immunity and the microbiota by performing a post hoc analysis of a clinical trial in which each of the 20 participants sequentially consumed vegan or ketogenic diets for 2 weeks ( NCT03878108 ). Using a multiomics approach including multidimensional flow cytometry, transcriptomic, proteomic, metabolomic and metagenomic datasets, we assessed the impact of each diet, and dietary switch, on host immunity and the microbiota...
January 30, 2024: Nature Medicine
https://read.qxmd.com/read/38285913/the-effect-of-the-ketogenic-diet-on-resistance-training-load-management-a-repeated-measures-clinical-trial-in-trained-participants
#14
JOURNAL ARTICLE
Salvador Vargas-Molina, Manuel García-Sillero, Diego A Bonilla, Jorge L Petro, Jerónimo García-Romero, Javier Benítez-Porres
BACKGROUND: The effect of low-carbohydrate high-fat dietary manipulation, such as the ketogenic diet (KD), on muscle strength assessment in resistance-training (RT) participants has focused on the one-repetition maximum test (1-RM). However, a pre-specified 1-RM value during an exercise training program disregards several confounding factors (i.e. sleep, diet, and training-induced fatigue) that affect the exerciser's "true" load and daily preparedness. We aimed to evaluate the effect of a 6-week RT program on load control-related variables in trained subjects following a KD intervention...
December 2024: Journal of the International Society of Sports Nutrition
https://read.qxmd.com/read/38140382/low-carbohydrate-high-fat-diet-alters-the-oral-microbiome-without-negating-the-nitrite-response-to-beetroot-juice-supplementation
#15
JOURNAL ARTICLE
Louise E Cato, Alannah K A McKay, Joanna E L'Heureux, Anni Vanhatalo, Andrew M Jones, Christopher D Askew, Gary J Slater, Louise M Burke
A low carbohydrate, high fat (LCHF) diet in athletes increases fat oxidation but impairs sports performance, potentially due to impaired exercise economy. Dietary nitrate supplementation can improve exercise economy via an increase in nitric oxide production, which is initiated by the reduction of nitrate to nitrite within the oral cavity. This reaction is dependent on the presence of nitrate-reducing oral bacteria, which can potentially be altered by dietary changes, including a LCHF diet. This study explored the effect of a LCHF diet on the oral microbiome and subsequent changes to plasma nitrite concentration following nitrate supplementation...
December 16, 2023: Nutrients
https://read.qxmd.com/read/38118233/evaluating-the-efficacy-of-a-ketogenic-diet-in-managing-drug-resistant-paediatric-dedpc5-related-epilepsy
#16
JOURNAL ARTICLE
Anna Winczewska-Wiktor, Małgorzata Braszka, Mia Harada-Laszlo, Magdalena Badura-Stronka, Izabela Kaczmarek, Monika Starczewska, Agnieszka Wencel-Warot, Barbara Steinborn, Aleksander Jamsheer
AIM: To evaluate the effectiveness of the ketogenic diet treatment in a cohort of patients with drug-resistant epilepsy with a mutation in the DEPDC5 gene. MATERIALS AND METHODS: We followed four paediatric patients with drug resistant DEPDC5-related epilepsy through a ketogenic diet (KD) treatment course. We analyzed the following parameters of their clinical profiles: past medical history, clinical characteristics of seizure morphology, EEG records pre- and post-KD treatment, the results of MRI head and neurological and psychological examinations (pre-treatment and throughout treatment course)...
December 19, 2023: Epilepsy & Behavior: E&B
https://read.qxmd.com/read/38117229/advances-in-the-treatment-of-functional-male-hypogonadism
#17
REVIEW
Giovanni Corona, Giulia Rastrelli, Clotilde Sparano, Linda Vignozzi, Alessandra Sforza, Mario Maggi
INTRODUCTION: Functional hypogonadism is frequently found in obese men, particularly those with metabolic complications. Several possible therapeutic approaches could be considered. AREAS COVERED: An extensive search on Medline, Embase, and Cochrane databases was performed to retrieve the available studies assessing the change of testosterone (T) and sexual function upon dieting or physical activity programs, as well as glucagon-like peptide 1 analogues. The role of lifestyle interventions associated with T replacement therapy (TRT) was also evaluated...
March 2024: Expert Review of Endocrinology & Metabolism
https://read.qxmd.com/read/38079311/ketogenic-diets-are-not-beneficial-for-athletic-performance
#18
JOURNAL ARTICLE
Louise M Burke, Jamie Whitfield
No abstract text is available yet for this article.
December 11, 2023: Medicine and Science in Sports and Exercise
https://read.qxmd.com/read/38079304/ketogenic-diets-are-beneficial-for-athletic-performance-response-to-burke-and-whitfield
#19
JOURNAL ARTICLE
Timothy David Noakes
No abstract text is available yet for this article.
December 11, 2023: Medicine and Science in Sports and Exercise
https://read.qxmd.com/read/38079303/ketogenic-diets-are-beneficial-for-athletic-performance
#20
JOURNAL ARTICLE
Timothy David Noakes
No abstract text is available yet for this article.
December 11, 2023: Medicine and Science in Sports and Exercise
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