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https://www.readbyqxmd.com/read/28088113/modulatory-effect-of-vanillic-acid-on-antioxidant-status-in-high-fat-diet-induced-changes-in-diabetic-hypertensive-rats
#1
Kolanji Vinothiya, Natarajan Ashokkumar
The worldwide incidence of diabetes has increased dramatically along with widespread lifestyle and dietary changes. Diets high in fat are strongly associated with the development of obesity and can induce insulin resistance in humans and animals. It is clear that obesity constitutes a risk factor for contributing to the development of type 2 diabetes. In the present study, we investigated the therapeutic potential action of vanillic acid on diabetes associated complications using a rat model. Rats were made diabetic hypertensive by high fat diet (HFD) for 20 weeks and were treated with vanillic acid (50mg/kg bw) for last 8 weeks...
January 11, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28088089/the-traumatic-potential-of-a-projectile-shot-from-a-sling
#2
Igor Borovsky, Zvi Lankovsky, Leonid Kalichman, Victor Belkin
Herein, we analyze the energy parameters of stones of various weights and shapes shot from a sling and based on this data evaluate its traumatic potential. Four police officers proficient in the use of a sling participated in the trials. The following projectile types, shot using an overhead technique at a target 100m away were: round steel balls of different sizes and weights (24mm, 57g; 32mm, 135g; 38mm, 227g); different shaped stones weighing 100-150g and 150-200g and a golf ball (47g). Our data indicated that projectiles shot from unconventional weapons such as a sling, have serious traumatic potential for unprotected individuals and can cause blunt trauma of moderate to critical severity such as fractures of the trunk, limb, and facial skull bone, depending on the weight and shape of the projectile and the distance from the source of danger...
October 26, 2016: Forensic Science International
https://www.readbyqxmd.com/read/28088084/correlates-of-anti-hepatitis-c-positivity-and-use-of-harm-reduction-services-among-people-who-inject-drugs-in-two-cities-in-croatia
#3
Senad Handanagic, Sandra Sevic, Jelena Barbaric, Zoran Dominkovic, Oktavija Dakovic Rode, Josip Begovac, Ivana Bozicevic
BACKGROUND: We assessed correlates of anti-hepatitis C (anti-HCV) positivity and utilization of needle and syringe exchange programs (NSEP) and opioid agonist treatment (OAT) among people who inject drugs (PWID) in two Croatian cities. METHODS: We conducted a cross-sectional study using respondent-driven (RDS) sampling among PWID in Rijeka (N=255) and Split (N=399). We used RDS-weighted population estimates and multivariable logistic regression to explore correlates of anti-HCV positivity and NSEP and OAT utilization...
December 7, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28088079/geographic-determinants-of-individual-obesity-risk-in-spain-a-multilevel-approach
#4
Athina Raftopoulou
This paper seeks to understand the determinants of individual body weight status and obesity risk in Spain by concurrently examining individual and regional characteristics. The data are drawn from the National Health Survey of Spain for the year 2011-2012 (INE-National Statistical Institute of Spain) and contain information for a representative sample of 12,671 adults across 50 provinces in Spain. A multilevel analysis is carried out to examine the determinants of individual weight status and obesity, controlling not only for the individual effects and those of the immediate environment but also for the broader setting to which individuals and their immediate environment belong...
January 3, 2017: Economics and Human Biology
https://www.readbyqxmd.com/read/28088020/sulphur-alters-chromium-vi-toxicity-in-solanum-melongena-seedlings-role-of-sulphur-assimilation-and-sulphur-containing-antioxidants
#5
Madhulika Singh, Bishwajit Kumar Kushwaha, Samiksha Singh, Vipin Kumar, Vijay Pratap Singh, Sheo Mohan Prasad
The present study investigates modulation in hexavalent chromium [Cr(VI) 25 μM] toxicity by sulphur (S; 0.5, 1.0 and 1.5 mM S as low (LS), medium (MS) and high sulphur (HS), respectively) in Solanum melongena (eggplant) seedlings. Biomass accumulation (fresh and dry weights), photosynthetic pigments, photosynthetic oxygen evolution and S content were declined by Cr(VI) toxicity. Furthermore, fluorescence characteristics (JIP-test) were also affected by Cr(VI), but Cr(VI) toxicity on photosystem II photochemistry was ameliorated by HS treatment via reducing damaging effect on PS II reaction centre and its reduction side...
December 27, 2016: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28088019/melatonin-and-resveratrol-reverse-the-toxic-effect-of-high-boron-b-and-modulate-biochemical-parameters-in-pepper-plants-capsicum-annuum-l
#6
Eleana Sarafi, Pavlos Tsouvaltzis, Christos Chatzissavvidis, Anastasios Siomos, Ioannis Therios
The objectives of this research were to test a possible involvement of melatonin (MEL) and resveratrol (RES) in restoring growth and to control boron (B) toxicity in peppers. The plants were subjected to four different nutrient solution treatments as following: 1) half-strength Hoagland's nutrient solution (Control), 2) half-strength Hoagland's nutrient solution+100 μM B (100 μMB), 3) half-strength Hoagland's nutrient solution+100 μM boron+100 μMresveratrol (100 μMRES), and 4) half-strength Hoagland's nutrient solution+100 μM B+1 μMmelatonin (1 μM MEL)...
December 23, 2016: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28087998/performance-evaluation-of-pride-unda-system-with-pyroprocessing-feed-material
#7
Su Jung An, Hee Seo, Chaehun Lee, Seong-Kyu Ahn, Se-Hwan Park, Jeong-Hoe Ku
The PRIDE (PyRoprocessing Integrated inactive DEmonstration) is an engineering-scale pyroprocessing test-bed facility that utilizes depleted uranium (DU) instead of spent fuel as a process material. As part of the ongoing effort to enhance pyroprocessing safeguardability, UNDA (Unified Non-Destructive Assay), a system integrating three different non-destructive assay techniques, namely, neutron, gamma-ray, and mass measurement, for nuclear material accountancy (NMA) was developed. In the present study, UNDA's NMA capability was evaluated by measurement of the weight, (238)U mass, and U enrichment of oxide-reduction-process feed material (i...
December 30, 2016: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28087923/enhanced-aerobic-sludge-granulation-by-seeding-concentrated-activated-sludge-with-ca-alginate-gel
#8
Can Sun
The present study focuses on the effect of Ca-alginate gel on aerobic sludge granulation. Three sequencing batch reactors (SBRs) seeded with different mixtures of Ca-alginate gel and activated sludge with the fraction (weight/weight of dry biomass) of 0%, 5.5% and 15.5% respectively. The granulation time of 14 days was obtained with 5.5% additive, whilst 32 days were needed to adapt aerobic granules developed with 0% Ca-alginate gel. Full granulation was achieved in the trial with 15.5% additive from the 20th day...
December 9, 2016: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/28087913/-cigarette-smoking-in-different-manners-induces-acute-lung-injury-in-rats
#9
Weiqiang Xiao, Guojun Zhou, Chengyun Xu, Jian Xu, Fangfang Huang, Xinbo Lu, Xia Li, Ximei Wu
Objective: To investigate the effects of cigarette smoking in different manners on acute lung injury in rats. Methods: The commercially available cigarettes with tar of 1,5, 11 mg were smoked in Canada depth smoking (health canada method, HCM) manner, and those with tar of 11 mg were also smoked in international standard (ISO) smoking manner. Rats were fixed and exposed to mainstream in a manner of nose-mouth exposure. After 28 days, the bronchoalveolar lavage fluids from left lung were collected for counting and classification of inflammatory cells and determination of pro-inflammatory cytokines IL-1β and TNF-α...
May 25, 2016: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/28087891/physical-activity-and-exercise-for-chronic-pain-in-adults-an-overview-of-cochrane-reviews
#10
REVIEW
Louise J Geneen, R Andrew Moore, Clare Clarke, Denis Martin, Lesley A Colvin, Blair H Smith
BACKGROUND: Chronic pain is defined as pain lasting beyond normal tissue healing time, generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep disturbances, poor quality of life, and healthcare costs. Chronic pain has a weighted mean prevalence in adults of 20%.For many years, the treatment choice for chronic pain included recommendations for rest and inactivity. However, exercise may have specific benefits in reducing the severity of chronic pain, as well as more general benefits associated with improved overall physical and mental health, and physical functioning...
January 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28087864/drug-induced-weight-gain-rethinking-our-choices
#11
REVIEW
Katherine H Saunders, Leon I Igel, Alpana P Shukla, Louis J Aronne
Weight gain secondary to medications is a potentially modifiable risk. Here's how to optimize drug choices for patients with several common conditions.
November 2016: Journal of Family Practice
https://www.readbyqxmd.com/read/28087862/is-the-rx-to-blame-for-the-patient-s-weight-gain
#12
EDITORIAL
John Hickner
Avoid prescribing medications that can cause weight gain in overweight and obese patients when possible, use the lowest effective dose when such agents are necessary, and warn patients of this adverse effect so that they can take precautions, such as walking an extra mile a day or giving up that high-calorie latte in the morning.
November 2016: Journal of Family Practice
https://www.readbyqxmd.com/read/28087796/prior-military-service-identity-stigma-and-mental-health-among-transgender-older-adults
#13
Charles P Hoy-Ellis, Chengshi Shiu, Kathleen M Sullivan, Hyun-Jun Kim, Allison M Sturges, Karen I Fredriksen-Goldsen
PURPOSE OF THE STUDY: Converging evidence from large community-based samples, Internet studies, and Veterans Health Administration data suggest that transgender adults have high rates of U.S. military service. However, little is known about the role of prior military service in their mental health later in life, particularly in relation to identity stigma. In this article, we examine relationships between prior military service, identity stigma, and mental health among transgender older adults...
February 2017: Gerontologist
https://www.readbyqxmd.com/read/28087795/who-says-i-do-the-changing-context-of-marriage-and-health-and-quality-of-life-for-lgbt-older-adults
#14
Jayn Goldsen, Amanda E B Bryan, Hyun-Jun Kim, Anna Muraco, Sarah Jen, Karen I Fredriksen-Goldsen
PURPOSE OF THE STUDY: Until recently, lesbian, gay, bisexual, and transgender (LGBT) adults were excluded from full participation in civil marriage. The purpose of this study is to examine how legal marriage and relationship status are associated with health-promoting and at-risk factors, health, and quality of life of LGBT adults aged 50 and older. DESIGN AND METHODS: We utilized weighted survey data from Aging with Pride: National Health, Aging, and Sexuality/Gender Study (NHAS) participants who resided in states with legalized same-sex marriage in 2014 (N = 1,821)...
February 2017: Gerontologist
https://www.readbyqxmd.com/read/28087793/race-ethnicity-and-health-related-quality-of-life-among-lgbt-older-adults
#15
Hyun-Jun Kim, Sarah Jen, Karen I Fredriksen-Goldsen
PURPOSE OF THE STUDY: Few existing studies have addressed racial/ethnic differences in the health and quality of life of lesbian, gay, bisexual, and transgender (LGBT) older adults. Guided by the Health Equity Promotion Model, this study examines health-promoting and health risk factors that contribute to racial/ethnic health disparities among LGBT adults aged 50 and older. DESIGN AND METHODS: We utilized weighted survey data from Aging with Pride: National Health, Aging, and Sexuality/Gender Study...
February 2017: Gerontologist
https://www.readbyqxmd.com/read/28087725/neurodevelopmental-outcomes-of-extremely-low-birthweight-infants-randomised-to-different-pco2-targets-the-phelbi-follow-up-study
#16
Ulrich H Thome, Orsolya Genzel-Boroviczeny, Bettina Bohnhorst, Manuel Schmid, Hans Fuchs, Oliver Rohde, Stefan Avenarius, Hans-Georg Topf, Andrea Zimmermann, Dirk Faas, Katharina Timme, Barbara Kleinlein, Horst Buxmann, Wilfried Schenk, Hugo Segerer, Norbert Teig, Annett Bläser, Roland Hentschel, Matthias Heckmann, Rolf Schlösser, Jochen Peters, Rainer Rossi, Wolfgang Rascher, Ralf Böttger, Jürgen Seidenberg, Gesine Hansen, Maria Zernickel, Harald Bode, Jens Dreyhaupt, Rainer Muche, Helmut D Hummler
BACKGROUND: Tolerating higher partial pressures of carbon dioxide (PCO2) in mechanically ventilated extremely low birthweight infants to reduce ventilator-induced lung injury may have long-term neurodevelopmental side effects. This study analyses the results of neurodevelopmental follow-up of infants enrolled in a randomised multicentre trial. METHODS: Infants (n=359) between 400 and 1000 g birth weight and 23 0/7-28 6/7 weeks gestational age who required endotracheal intubation and mechanical ventilation within 24 hours of birth were randomly assigned to high PCO2 or to a control group with mildly elevated PCO2 targets...
January 13, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28087653/identification-of-regulatory-networks-and-hub-genes-controlling-soybean-seed-set-and-size-using-rna-sequencing-analysis
#17
Juan Du, Shoudong Wang, Cunman He, Bin Zhou, Yong-Ling Ruan, Huixia Shou
To understand the gene expression networks controlling soybean seed set and size, transcriptome analyses were performed in three early seed developmental stages, using two genotypes with contrasting seed size. The two-dimensional data set provides a comprehensive and systems-level view on dynamic gene expression networks underpinning soybean seed set and subsequent development. Using pairwise comparisons and weighted gene coexpression network analyses, we identified modules of coexpressed genes and hub genes for each module...
January 13, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28087545/predictors-of-public-support-for-nutrition-focused-policy-systems-and-environmental-change-strategies-in-los-angeles-county-2013
#18
Brenda Robles, Tony Kuo
BACKGROUND: Since 2010, federal and local agencies have invested broadly in a variety of nutrition-focused policy, systems and environmental change (PSE) initiatives in Los Angeles County (LAC). To date, little is known about whether the public supports such efforts. We address this gap in the literature by examining predictors of support for a variety of PSEs. METHODS: Voters residing in LAC (n=1007) were randomly selected to participate in a cross-sectional telephone survey commissioned by the LAC Department of Public Health...
January 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28087523/use-of-acupuncture-in-the-usa-changes-over-a-decade-2002-2012
#19
Jia Cui, Shaobai Wang, Jiehui Ren, Jun Zhang, Jun Jing
BACKGROUND: The use of acupuncture has gained popularity in the USA. The number of acupuncture users and licensed acupuncturists increased by 50% and 100%, respectively, between 2002 and 2012, coinciding with increasing acknowledgement of the importance and efficacy of acupuncture over this time period. METHODS: This paper presents new findings from the complementary health approaches section of the 2012 National Health Interview Survey (n=33 373 respondents)...
January 13, 2017: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/28087520/atheroprotective-vaccination-with-mhc-ii-restricted-apob-peptides-induces-peritoneal-il-10-producing-cd4-t-cells
#20
Takayuki Kimura, Kevin Tse, Sara McArdle, Teresa Gerhardt, Jacqueline Miller, Zbigniew Mikulski, John Sidney, Alessandro Sette, Dennis Wolf, Klaus Ley
Although immunization with MHC class II-restricted ApoB peptides has been shown to be atheroprotective, the mechanism is unclear. Here, we investigated CD4(+) T cell populations in immunized atherosclerotic mice. Peptides (16-mers) from mouse ApoB, the core protein of low-density lipoprotein (LDL), were screened for binding to I-A(b) by computer prediction and confirmed by radiolabeled peptide competition. Three new peptides, P101 (FGKQGFFPDSVNKALY, 5.5 nM IC50), P102 (TLYALSHAVNSYFDVD, 6.8 nM), and P103 (LYYKEDKTSLSASAAS, 95 nM) were tested in an atherosclerosis model (Apoe(-/-) mice on western diet)...
January 13, 2017: American Journal of Physiology. Heart and Circulatory Physiology
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