Read by QxMD icon Read


Alekxander Popov, Zinaida K Blinnikova, Maria P Tsyurupa, Vadim A Davankov
New restricted access materials based on microporous hypercrosslinked polystyrene have been developed. The materials are aimed at the use as packings for solid-phase extraction cartridges to isolate low-molecular-weight analytes from biological fluids (for instance, blood plasma or serum). Two features distinguish these polymers from all known restricted access materials. The first one consists in that the microporous hypercrosslinked polystyrene not only exclude proteins from the sorbent phase but also do not adsorb them on the bead outer surface and so they do not cause coagulation of blood protein components...
June 21, 2018: Journal of Separation Science
Francielly Mourão Gasparotto, Francislaine Aparecida Dos Reis Lívero, Rhanany Allan Caloi Palozi, Maria Leticia Ames, Bruna Nunes, Guilherme Donadel, Rita de Cassia Lima Ribeiro, Emerson Luiz Botelho Lourenço, Cândida Aparecida Leite Kassuya, Arquimedes Gasparotto Junior
Excess weight and dyslipidemia are among the most serious health problems in Western societies. These conditions enhance the risk of cardiac disease and have been linked with a higher prevalence of cardiac arrhythmias and sudden death. The present study investigated the cardioprotective effects of Echinodorus grandiflorus on ventricular remodeling in rabbits that were fed a 1% cholesterol-rich diet. We first obtained an ethanol-soluble fraction of E. grandiflorus and performed a detailed phytochemical study by liquid chromatography-DAD/ESI-MS...
June 21, 2018: Planta Medica
Mehdi Menai, Hélène Charreire, Pilar Galan, Chantal Simon, Julie-Anne Nazare, Camille Perchoux, Christiane Weber, Christophe Enaux, Serge Hercberg, Léopold Fezeu, Jean-Michel Oppert
BACKGROUND: Research on the associations between walking and cycling with obesity-related phenotypes is growing but relies mostly on the use of BMI. The purpose of this study was to analyze associations of walking and cycling behaviors assessed separately with various obesity markers in French adults. METHODS: In 12,776 adult participants (71.3% women) of the on-going NutriNet Santé web-cohort, we assessed by self-report past-month walking and cycling (for commuting, errands and leisure), and obesity measures were taken during a visit at a clinical center (weight, height, waist circumference, and percent body fat by bioimpedance)...
June 22, 2018: Obesity Facts
Junyu Zhao, Chunmei Xu, Jinming Yao, Changzhen Yu, Lin Liao, Jianjun Dong
BACKGROUND/AIMS: Experimental studies have reported the antineoplastic effects of statins in thyroid carcinoma; however, observational studies suggested that statins might increase the risk of thyroid carcinoma. Therefore, this study evaluated the antineoplastic effects of statins in both in vitro studies and animal models, as well as the epidemiological evidence. METHODS: Databases-PubMed, Cochrane Library, SinoMed, CNKI, Wanfang, and clinical trial registries- were searched...
June 19, 2018: Cellular Physiology and Biochemistry
Yang Song, Ling-Lei Zhang, Jia Li, Xiao-Jia He, Min Chen, Yun Deng
Water contamination by nickel (Ni) has become an increasing concern in recent decades. Hydrilla verticillata (L.f.) Royle has been recognized as a promising accumulator of several potentially toxic elements (PTEs) in phytoremediation, but its Ni-accumulation characteristics and its mechanisms of tolerance to Ni remain largely unknown. This research investigated the biochemical responses of leaves and stems of H. verticillata to various concentrations of Ni (5, 10, 15, 20, and 40 μM) over periods of 7, 14, or 21 days...
June 18, 2018: Ecotoxicology and Environmental Safety
Junmei Zhang, Lingxiao Yang, Abdelwahid Mellouki, Jianmin Chen, Xiangfeng Chen, Ying Gao, Pan Jiang, Yanyan Li, Hao Yu, Wenxing Wang
Ambient measurements of PM2.5 -bounded polycyclic aromatic hydrocarbons (PAHs), nitro-PAHs (NPAHs), and oxy-PAHs (OPAHs) were conducted during the summer in Jinan, China, an urban site, and at Tuoji island and Mt. Tai, two background locations. 3.5 h and 11.5 h sampling intervals in daytime and nighttime were utilized to research the diurnal variations of PAHs, NPAHs, and OPAHs. The concentrations of PAHs, NPAHs, and OPAHs were highest at the urban site and lowest at the marine site. The diurnal patterns of PAHs and NPAHs at the urban and marine sites were dissimilar to those observed at the mountain site partly due to the influence of the boundary layer...
June 14, 2018: Chemosphere
Zhenhua Song, Yan Liu, Rong Song, Zhenguang Chen, Jianyong Yang, Chao Zhang, Qing Jiang
A novel sparsity-based stochastic pooling which integrates the advantages of max-pooling, average-pooling and stochastic pooling is introduced. The proposed pooling is designed to balance the advantages and disadvantages of max-pooling and average-pooling by using the degree of sparsity of activations and a control function to obtain an optimized representative feature value ranging from average value to maximum value of a pooling region. The optimized representative feature value is employed for probability weights assignment of activations in normal distribution...
June 15, 2018: Neural Networks: the Official Journal of the International Neural Network Society
Eloise Crush, Louise Arseneault, Terrie E Moffitt, Andrea Danese, Avshalom Caspi, Sara R Jaffee, Timothy Matthews, Helen L Fisher
Experiencing multiple types of victimization (poly-victimization) during adolescence is associated with the onset of psychotic experiences (such as hearing voices, having visions, or being extremely paranoid). However, many poly-victimized adolescents will not develop such subclinical phenomena and the factors that protect them are unknown. This study investigated whether individual, family, or community-level characteristics were associated with an absence of psychotic experiences amongst poly-victimized adolescents...
June 12, 2018: Journal of Psychiatric Research
Martina Trckova, Alena Lorencova, Vladimir Babak, Jiri Neca, Miroslav Ciganek
A three-week trial was conducted to evaluate the effects of leonardite and lignite, natural sources of humic substances, on selected indicators of health status of weaned piglets. A total of 45 weaned piglets were assigned to three dietary treatments: Control - basal diet without any medication; Leonardite or Lignite - diet supplemented with lignite or leonardite at a dose of 20 g/kg, respectively. Leonardite differed from lignite in the content of humic substances and minerals. Diarrhoea incidence and severity, growth performance, haematological and biochemical status, biomarkers of oxidative stress, serum fatty acid (FA) profile and faecal microbiota composition were monitored...
June 12, 2018: Research in Veterinary Science
Didem Dagdeviren, Zana Kalajzic, Douglas J Adams, Ivo Kalajzic, Alan Lurie, Maija I Mednieks, Arthur R Hand
OBJECTIVE: To determine if spaceflight and microgravity affect non-weight bearing bones and development and mineralization of teeth, reasoning that combining an organ and a cellular level approach can lead to greater insights about these effects. DESIGN: Mandibles and incisors of mice flown on the US STS-135 space shuttle mission and the Russian Bion-M1 satellite were studied using micro-computed tomography and immunohistochemistry. Ground controls were mice housed in standard vivarium cages and flight habitats...
June 7, 2018: Archives of Oral Biology
Vibhu Krishnan Viswanathan, Jeff Hatef, Sina Aghili, Amy Minnema, H Francis Farhadi
OBJECTIVE: Segmental instability is traditionally investigated with flexion and extension (F/E) X-rays. We sought to determine whether motion between upright and supine (U/S) views can serve as an alternative sensitive diagnostic tool that predicts similar outcomes. METHODS: Ambispective collection of data was performed for 222 consecutive patients that underwent transforaminal lumbar interbody fusion (TLIF). Patients were divided into either Group 1 (≥3 mm spondylolisthesis difference between F/E X-rays) or Group 2 (≥3 mm spondylolisthesis difference between U/S imaging and otherwise not meeting Group 1 criteria)...
June 18, 2018: World Neurosurgery
Ju-Hwi Kim, Woo-Youl Jang, Tae-Young Jung, Kyung-Sub Moon, Shin Jung, Kyung-Hwa Lee, In-Young Kim
In this study, we report a case of solitary Langerhans cell histiocytosis (LCH) without skull or systemic lesions, including reviewing the initial magnetic resonance (MR) findings of cerebral LCH. A 36-year-old male patient presented with generalized tonic-clonic type seizure. Brain MR imaging showed a 3cm mass lesion involving the right frontal lobe. It showed iso-intensity on T1-weighted images and hyperintensity on T2-weighted images. After gadolinium enhancement, the mass showed heterogeneous enhancement with perilesional edema and additional adjacent leptomeningeal enhancement...
June 18, 2018: World Neurosurgery
Hiwa O Ahmed, Sarmad H Arif, Sabah Abid Abdulhakim, Aram Kakarash, Mohammad Amin Ali Omer, Aree Majid Nuri, Hallo H Omer, Hardi Kareem Jalal, Shahen H Omer, Nashadin Aziz Muhammad
BACKGROUND: The increasing incidence of morbid obesity suggests that the quantity of bariatric surgical procedures will continue to multiply each year, many patients who have experienced massive weight loss are left with the dissatisfying consequences of loose and redundant skin, resulting in contour irregularities, an aesthetic and functional problem, and profound dissatisfaction with appearance, residual body image dissatisfaction, There is a subsequent increase in the number of patients seeking additional corrective procedures including abdominoplasty which considered as one of the most popular body-contouring procedures...
June 18, 2018: International Journal of Surgery
Gabriela Arandia, Daniela Sotres-Alvarez, Anna Maria Siega-Riz, Elva M Arredondo, Mercedes R Carnethon, Alan M Delamater, Linda C Gallo, Carmen R Isasi, Ashley N Marchante, David Pritchard, Linda Van Horn, Krista M Perreira
BACKGROUND: Acculturation among Hispanic/Latinos has been linked to deteriorating dietary quality that may contribute to obesity risks. This study examined the relationship between acculturation, ethnic identity, and dietary quality in U.S. Hispanic/Latino youth. METHODS: This cross-sectional study included 1298 Hispanic/Latino youth ages 8-16 from the Hispanic Community Health Study/Study of Latino Youth (HCHS/SOL Youth), an ancillary study of offspring of participants in the adult HCHS/SOL cohort...
June 18, 2018: Appetite
Flávia C M Pinto, Rosangela R De-Carvalho, Ana Cecilia A X De-Oliveira, Isabella F Delgado, Francisco J R Paumgartten
β-ionone (BIO) is used in fragrances, toiletries and non-cosmetic products, and as a flavor food additive. Notwithstanding the widespread human exposure, there are limited data on the reproductive toxicity of BIO. This study evaluated the developmental toxicity of BIO (0, 125, 250, 500 and 1000 mg/kg body weight/day) given orally to rats on days 6-15 of gestation (GD6-15). C-section was on GD21 and implantations, living and dead fetuses and resorptions were recorded. Fetuses were weighed, and examined for external abnormalities and skeleton and visceral anomalies...
June 18, 2018: Regulatory Toxicology and Pharmacology: RTP
Kyoung Hee Seo, Sun-Young Jung, Yeonsun Jin, Sung Hoon Lee
AIMS: Anoctamin-1 (TMEM16A) is a calcium-activated chloride channel that is involved in numerous physiological conditions. Its role has been identified in electrophysiological and histological studies of genetic knockout animals. Recent cellular localization studies have shown that anoctamin-1 is co-expressed with presynaptic proteins, therefore its role in presynaptic terminals has been suggested. However, behavioral studies are lacking because conventional knockouts of anoctamin-1 are lethal after birth...
June 18, 2018: Life Sciences
Z A Grieb, M A Holschbach, J S Lonstein
Most maternal caregiving behaviors change across lactation to match the developmental needs of the continuously aging offspring. However, it is mostly unknown whether the dams' postpartum stage or litter age is the primary driving force of these changes. In this study, postnatal day 1 and 8 litters were cross-fostered or in-fostered to postpartum day 1 or 8 dams. Five days later, undisturbed observations of maternal caregiving behaviors were performed on the subsequent two days. We found a main effect of dams' postpartum stage, which was driven by an interaction between postpartum stage and litter age, on the frequency that mothers spent with the pups and displayed erect postures over them (hovering over and kyphosis): early-postpartum dams were in contact with younger litters and in erect postures more often with younger litters compared to later-postpartum dams with younger litters...
June 18, 2018: Physiology & Behavior
Xiangcheng Pan, Chunna Lv, Congze He
A rapid oxygen-initiated and -regulated controlled radical polymerization was conducted under ambient temperature and atmosphere. The reaction between triethylborane and oxygen provides ethyl radicals which initiate and mediate the radical polymerization. The controlled radical polymerization was achieved using RAFT chain transfer agents (CTA) without any process of removing oxygen, providing well-defined polymers with almost full conversion (>95%) in short period (15 mins). High-throughput screening was used to discover the suitable conditions for various CTA and monomers...
June 21, 2018: Angewandte Chemie
Paul A Shuper, Narges Joharchi, Jürgen Rehm
BACKGROUND: Although it has been purported that HIV-positive individuals may experience a greater degree of intoxication than HIV-negative individuals following acute alcohol consumption, no research to date has empirically tested this supposition. The present investigation entailed a randomized controlled experiment to identify whether the administration of a weight-specified dose of alcohol would lead to differential blood alcohol concentrations (BACs) among HIV-positive versus HIV-negative men...
June 21, 2018: Alcoholism, Clinical and Experimental Research
Dilmurodjon Eshmuminov, Filippo Leoni, Marcel André Schneider, Dustin Becker, Xavier Muller, Christopher Onder, Max Hefti, Martin Schuler, Philipp Dutkowski, Rolf Graf, Philipp Rudolf von Rohr, Pierre-Alain Clavien, Lucia Bautista Borrego
Liver machine perfusion at normothermic temperature (NMP) is a promising way to preserve and evaluate extended criteria donor livers. Currently, no consensus exists in methodology and perfusion protocols. Here, the authors performed a systematic literature search to identify human and porcine studies reporting on liver NMP with red blood cells. A qualitative synthesis was performed concerning technical aspects of machine perfusion, fluid composition, gas supply and liver positioning. 37 publications including 11 human and 26 porcine studies were considered for qualitative synthesis...
June 21, 2018: Transplant International: Official Journal of the European Society for Organ Transplantation
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"