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https://www.readbyqxmd.com/read/26877375/p-076-chronic-renal-failure-and-parathyroid-hormone
#1
O Kharoubi, A Benglia
OBJECTIFS: L'insuffisance rénale chronique (IRC) se définit comme une diminution prolongée et souvent définitive des fonctions exocrines et endocrines du rein. Cette maladie est évolutive, et lorsqu'elle atteint un stade terminal, elle est incompatible avec la vie. Afin d'évaluer cliniquement les troubles phosphocalciques, notre travail est mené chez les patients atteints d'IRC de l'ouest d'Algérie (Oran, Mostaganem, Ain Témouchent,…). Notre étude a porté sur 62 malades insuffisants rénaux chroniques...
December 2015: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/26849079/durable-response-to-treatment-with-combination-radiotherapy-and-high-dose-interleukin-2-in-metastatic-chromophobe-variant-renal-cell-carcinoma
#2
Joseph Merriman, Jonathan Tward, Dan Albertson, Christopher Dechet, Neeraj Agarwal
This is a report of chromophobe renal cell carcinoma (ChRCC), a rare entity that accounts for 6% to 11% of cases of renal cell carcinoma (RCC). ChRCC is considered to yield a good prognosis as it typically presents as an early stage tumor with longer overall survival when compared with clear cell RCC; however, metastatic disease negates this survival difference and is characterized by poor prognosis. The available clinical investigations supporting the guidelines for treatment of metastatic RCC are predominantly based on clear cell RCC studies...
February 2016: Journal of Immunotherapy
https://www.readbyqxmd.com/read/25168556/use-of-a-polytetrafluoroethylene-gore-tex-bolster-to-close-the-renal-parenchymal-defect-during-open-partial-nephrectomy
#3
Jeffrey D Redshaw, Jeremy M West, Robert A Stephenson, William T Lowrance, Blake D Hamilton, Andrew W Southwick, Christopher B Dechet
INTRODUCTION: Numerous surgical techniques have been described to facilitate closure of the renal parenchymal defect. We sought to describe the operative technique and define the safety and efficacy of using an expanded polytetrafluoroethylene (GORE-TEX; WL Gore and Associates, Flagstaff, AZ) bolster to aid in closure of the renal parenchymal defect at the time of open partial nephrectomy (OPN). TECHNICAL CONSIDERATIONS: A retrospective review of 175 patients who underwent an OPN using an expanded polytetrafluoroethylene (ePTFE) bolster at the Huntsman Cancer Hospital, University of Utah and Salt Lake City Veterans Affairs Medical Center from March 2005 to February 2013 was conducted...
September 2014: Urology
https://www.readbyqxmd.com/read/25139069/the-charlson-comorbidity-index-predicts-survival-after-disease-recurrence-in-patients-following-radical-cystectomy-for-urothelial-carcinoma-of-the-bladder
#4
Roman Mayr, Matthias May, Maximilian Burger, Thomas Martini, Armin Pycha, Christopher Dechet, Michele Lodde, Evi Comploj, Wolf F Wieland, Stefan Denzinger, Wolfgang Otto, Atiqullah Aziz, Hans-Martin Fritsche, Michael Gierth
OBJECTIVE: To identify prognostic clinical and histopathological parameters, including comorbidity indices at the time of radical cystectomy (RC), for overall survival (OS) after recurrence following RC for urothelial carcinoma of the bladder (UCB). MATERIALS AND METHODS: A retrospective multicenter study was carried out in 555 unselected consecutive patients who underwent RC with pelvic lymph node dissection for UCB from 2000 to 2010. A total of 227 patients with recurrence comprised our study group...
2014: Urologia Internationalis
https://www.readbyqxmd.com/read/25138778/preoperative-c-reactive-protein-in-the-serum-a-prognostic-biomarker-for-upper-urinary-tract-urothelial-carcinoma-treated-with-radical-nephroureterectomy
#5
MULTICENTER STUDY
Atiqullah Aziz, Michael Rink, Georgios Gakis, Luis A Kluth, Christopher Dechet, Florian Miller, Wolfgang Otto, Michael Gierth, Stefan Denzinger, Christian Schwentner, Arnulf Stenzl, Margit Fisch, Maximilian Burger, Hans-Martin Fritsche
OBJECTIVE: To investigate the impact of preoperative serum C-reactive protein (CRP) on clinicopathological features and prognosis in patients with upper tract urothelial cancer (UTUC) after radical nephroureterectomy (RNU). PATIENTS AND METHODS: Data of 265 patients from three German centers who underwent RNU for UTUC without neoadjuvant chemotherapy between 1990 and 2012 were evaluated. Mean follow-up was 37 months (interquartile range 9-48). CRP was analyzed as a categorical and continuous variable for the prediction of recurrence-free survival (RFS), disease-specific survival (DSS) and all-cause survival (ACS) using uni- and multivariate Cox regression analyses...
2014: Urologia Internationalis
https://www.readbyqxmd.com/read/25076040/outbreaks-caused-by-sprouts-united-states-1998-2010-lessons-learned-and-solutions-needed
#6
Amy M Dechet, Karen M Herman, Cary Chen Parker, Peter Taormina, Joy Johanson, Robert V Tauxe, Barbara E Mahon
After a series of outbreaks associated with sprouts in the mid-1990s, the U.S. Food and Drug Administration (FDA) published guidelines in 1999 for sprouts producers to reduce the risk of contamination. The recommendations included treating seeds with an antimicrobial agent such as calcium hypochlorite solution and testing spent irrigation water for pathogens. From 1998 through 2010, 33 outbreaks from seed and bean sprouts were documented in the United States, affecting 1330 reported persons. Twenty-eight outbreaks were caused by Salmonella, four by Shiga toxin-producing Escherichia coli, and one by Listeria...
August 2014: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/24969739/comparison-of-complications-from-radical-cystectomy-between-old-old-versus-oldest-old-patients
#7
MULTICENTER STUDY
Evi Comploj, Jeremy West, Michael Mian, Luis Alex Kluth, Alexander Karl, Christopher Dechet, Shahrokh F Shariat, Christian G Stief, Emanuela Trenti, Salvatore Palermo, Michele Lodde, Wolfgang Horninger, Stephan Madersbacher, Armin Pycha
INTRODUCTION: The purpose of this study was to evaluate and compare complications after radical cystectomy in patients aged ≥75 years. MATERIALS AND METHODS: 251 patients aged 75-95 years (median 79) underwent radical cystectomy between 2000 and 2012 at four institutions. The patients were divided into two groups: ≥75-84 years of age (group 1) versus ≥85 years of age (group 2). Comorbidities, body mass index, and complications were obtained retrospectively, except at the Central Hospital of Bolzano and Weill Cornell Medical Center, which collected data prospectively...
2015: Urologia Internationalis
https://www.readbyqxmd.com/read/24922674/long-term-follow-up-of-intermediate-risk-non-muscle-invasive-bladder-cancer-sub-classified-by-multi-coloured-fish
#8
Christine Mian, Evi Comploj, Elisabeth Resnyak, Emanuela Trenti, Salvatore Palermo, Michele Lodde, Alexander Pycha, Andrea Ambrosini-Spaltro, Christopher B Dechet, Armin Pycha
AIM: To examine the long-term follow-up of patients with that previously underwent risk stratification based on multicolour FISH testing. PATIENTS AND METHODS: On 81 patients with intermediate-risk urothelial carcinoma, a multicolour-FISH was performed. Patients were sub-divided into low- and high-risk groups based on chromosomal patterns. Univariate analysis, using Mantel-Cox log-rank test for disease-free, progression-free survival and overall survival, was employed to determine the prognostic significance of FISH analysis...
June 2014: Anticancer Research
https://www.readbyqxmd.com/read/24895114/concomitant-seminal-vesicle-invasion-in-pt4a-urothelial-carcinoma-of-the-bladder-with-contiguous-prostatic-infiltration-is-an-adverse-prognosticator-for-cancer-specific-survival-after-radical-cystectomy
#9
COMPARATIVE STUDY
Matthias May, Sabine Brookman-May, Maximilian Burger, Christian Gilfrich, Hans-Martin Fritsche, Michael Rink, Felix Chun, Margit Fisch, Florian Roghmann, Joachim Noldus, Roman Mayr, Armin Pycha, Vladimir Novotny, Manfred Wirth, Stefan Vallo, Axel Haferkamp, Jan Roigas, Antonin Brisuda, Regina Stredele, Björn Volkmer, Christopher Dechet, Marco Schnabel, Stefan Denzinger, Christian G Stief, Patrick J Bastian, Atiqullah Aziz
PURPOSE: To evaluate the prognostic value of concomitant seminal vesicle invasion (cSVI) in patients with urothelial carcinoma of the bladder (UCB) and contiguous prostatic stromal infiltration in a large cystectomy series. METHODS: A total of 385 patients with UCB and contiguous prostatic infiltration comprised our study. Patients were divided in two groups according to cSVI. Median follow-up was 36 months (interquartile range 11-74); the primary end point was cancer-specific mortality...
November 2014: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/24817140/prognostic-impact-of-infiltration-of-the-vagina-and-or-uterus-in-women-undergoing-anterior-pelvic-exenteration-for-urothelial-carcinoma-of-the-bladder-results-of-a-contemporary-multicentre-series
#10
MULTICENTER STUDY
Matthias May, Atiqullah Aziz, Sabine Brookman-May, Florian Roghmann, Joachim Noldus, Michael Rink, Felix Chun, Margit Fisch, Vladimir Novotny, Manfred Wirth, Roman Mayr, Armin Pycha, Antonin Brisuda, Björn Volkmer, Regina Stredele, Christopher Dechet, Stefan Vallo, Axel Haferkamp, Marco Schnabel, Stefan Denzinger, Jan Roigas, Christian G Stief, Christian Gilfrich, Patrick J Bastian, Jörg B Engel, Maximilian Burger, Hans-Martin Fritsche
PURPOSE: To evaluate for the first time the prognostic significance of female invasive patterns in stage pT4a urothelial carcinoma of the bladder in a large series of women undergoing anterior pelvic exenteration. PATIENTS AND METHODS: Our series comprised of 92 female patients in total of whom 87 with known invasion patterns were eligible for final analysis. Median follow-up for evaluation of cancer-specific mortality (CSM) was 38 months (interquartile ranges, 21-82 months)...
March 2015: World Journal of Urology
https://www.readbyqxmd.com/read/24441240/novel-molecular-aberrations-and-pathologic-findings-in-a-tubulocystic-variant-of-renal-cell-carcinoma
#11
Nikhil A Sangle, Rong Mao, Shashirekha Shetty, Joshua D Schiffman, Christopher Dechet, Lester Layfield, Neeraj Agarwal, Ting Liu
Tubulocystic renal cell carcinoma (TRCC) is an indolent type of renal cell carcinoma with a good prognosis based on the limited number of published cases. Herein, we describe the unusual clinical, pathologic and molecular findings in a case of TRCC. Our patient with TRCC had two local recurrences and a brain metastasis following radical nephrectomy. Unusual histologic findings included focal solid growth pattern and cytologic atypia. A genome-wide molecular inversion probe assay identified copy number (CN) loss in three chromosome regions and one region with copy-neutral loss of heterozygosity (copy-neutral LOH)...
October 2013: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/24267105/comparison-of-radical-cystectomy-with-conservative-treatment-in-geriatric-%C3%A2-80-patients-with-muscle-invasive-bladder-cancer
#12
COMPARATIVE STUDY
Thomas Martini, Roman Mayr, Clemens Wehrberger, Christopher Dechet, Michele Lodde, Salvatore Palermo, Emanuela Trenti, Evi Comploj, Armin Pycha, Stephan Madersbacher
INTRODUCTION: The aim of this study was to compare overall survival in elderly patients (≥ 80 years) with muscle-invasive bladder cancer (MIBC) undergoing either radical cystectomy (RC) or conservative treatment. MATERIAL AND METHODS: We performed a retrospective, comparative analysis of overall- and cancer-specific survival in octagenarians with MIBC (≥ pT2) submitted to RC or conservative treatment. Uni- and multivariable Cox regression analysis were performed to assess predictors of overall survival...
September 2013: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/24166290/perforation-during-tur-of-bladder-tumours-influences-the-natural-history-of-superficial-bladder-cancer
#13
Evi Comploj, Christopher B Dechet, Michael Mian, Emanuela Trenti, Salvatore Palermo, Michele Lodde, Christine Mian, Andrea Ambrosini-Spaltro, Wolfgang Horninger, Armin Pycha
OBJECTIVES: Bladder perforation is the second most common complication during transurethral resection of bladder tumours. It is unknown whether perforation affects the natural history of the tumour through cell seeding. The aim of this study was to study the impact of perforation on the oncologic outcomes of bladder carcinoma. MATERIALS AND METHODS: Between 2003 and 2007, 926 consecutive patients underwent transurethral resection of bladder tumours at our institution; 327 cases were staged ≥ pT2 and were treated immediately with cystectomy and/or multimodal therapy and therefore excluded from the study...
October 2014: World Journal of Urology
https://www.readbyqxmd.com/read/24050893/climacturia-after-definitive-treatment-of-prostate-cancer
#14
Brock B O'Neil, Angela Presson, John Gannon, Robert A Stephenson, William Lowrance, Christopher B Dechet, Jonathan D Tward, Jeremy B Myers, William O Brant
PURPOSE: Prostate cancer treatment results in several sexually related side effects beyond the well studied erectile dysfunction. Climacturia (leakage of urine during orgasm) has been reported after prostatectomy but studies have been limited by multiple factors. In this study we examine the prevalence, causes and impact on orgasm function of climacturia after definitive treatment of prostate cancer with surgery or radiation. MATERIALS AND METHODS: A total of 906 anonymous surveys were sent to patients with prostate cancer treated with surgery and/or radiation...
January 2014: Journal of Urology
https://www.readbyqxmd.com/read/24044918/cytology-as-an-alternative-to-frozen-section-at-the-time-of-nephron-sparing-surgery-to-evaluate-surgical-margin-status
#15
COMPARATIVE STUDY
Salvatore M Palermo, Christopher Dechet, Emanuela Trenti, Christine Mian, Michele Lodde, Evi Comploj, Guido Mazzoleni, Esther Hanspeter, Andrea Ambrosini Spaltro, Roman Mayr, Armin Pycha
OBJECTIVE: To evaluate quick-staining cytology as an alternative method to intraoperative frozen sectioning after nephron-sparing nephrectomy. MATERIALS AND METHODS: Eighty-two partial nephrectomies were performed with intraoperative quick-staining cytology and frozen section evaluation. The results of both were compared with permanent histology as the gold standard. RESULTS: After partial nephrectomy, permanent histologic surgical margins were positive in 8 of 82 (9...
November 2013: Urology
https://www.readbyqxmd.com/read/24044916/reply
#16
Christopher Dechet, Emanuela Trenti
No abstract text is available yet for this article.
November 2013: Urology
https://www.readbyqxmd.com/read/24043536/-does-the-surgeon-have-an-influence-on-clinical-voiding-parameters-and-postoperative-sexual-function-after-turp
#17
COMPARATIVE STUDY
B Friedhelm, L Berner, C Dechet, A Presson, A Pycha
BACKGROUND: Benign prostate syndrome (BPS) is a common phenomenon in the aging male. Transurethral resection of the prostate (TURP) remains the international standard of care for -patients requiring surgical intervention for BPS. Although the voiding improvement following TURP is well-documented, controversy exists regarding its effect on post-operative sexual function. In this study we investigated the possible influence of individual surgeons on clinical voiding parameters and post-operative sexual function after TURP...
September 2013: Aktuelle Urologie
https://www.readbyqxmd.com/read/23870420/patient-and-provider-attitudes-toward-genomic-testing-for-prostate-cancer-susceptibility-a-mixed-method-study
#18
Wendy C Birmingham, Neeraj Agarwal, Wendy Kohlmann, Lisa G Aspinwall, Mary Wang, Jay Bishoff, Christopher Dechet, Anita Y Kinney
BACKGROUND: The strong association between family history and prostate cancer (PCa) suggests a significant genetic contribution, yet specific highly penetrant PCa susceptibility genes have not been identified. Certain single-nucleotide-polymorphisms have been found to correlate with PCa risk; however uncertainty remains regarding their clinical utility and how to best incorporate this information into clinical decision-making. Genetic testing is available directly to consumers and both patients and healthcare providers are becoming more aware of this technology...
2013: BMC Health Services Research
https://www.readbyqxmd.com/read/23824929/-henoch-sch%C3%A3-nlein-purpura-resulting-in-an-obstructive-bladder-mass
#19
E Comploj, W Cassar, E Trenti, S Palermo, P Reinstadler, C Ladurner, C Dechet, A Pycha
Henoch-Schönlein purpura (HSP) is the most common form of an immunological systemic vasculitis of childhood. The classic clinical symptoms include purpuric rash, abdominal pain, arthralgias, and haematuria, but the spectrum of HSP may vary to very rare forms. This article reports on an 8-year-old girl with a Henoch-Schönlein purpura (HSP) which resulted in an obstructive bladder mass and subsequent urinary retention. This is the first case reported in the literature, describing such a course.
November 2013: Aktuelle Urologie
https://www.readbyqxmd.com/read/23790712/conservative-management-of-paediatric-renal-abscess
#20
MULTICENTER STUDY
Evi Comploj, Walburga Cassar, Alessandra Farina, Paolo Gasparella, Emanuela Trenti, Salvatore Palermo, Christopher Burr Dechet, Paolo Caione, Armin Pycha
OBJECTIVE: Renal abscesses in the paediatric patient population are a rare entity. Patients are usually treated with percutaneous surgical drainage of the renal abscess as conservative treatment with broad-spectrum antibiotics is not considered as effective. We describe the conservative management of renal abscesses without percutaneous drainage in 6 children. MATERIALS AND METHODS: Six patients with a median age of 31 months, admitted over a 6 year period at two medical centers, were retrospectively studied...
December 2013: Journal of Pediatric Urology
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