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https://www.readbyqxmd.com/read/29469856/spatially-incoherent-common-path-off-axis-color-digital-holography
#1
Cuong M Nguyen, Dilband Muhammad, Hyuk-Sang Kwon
We describe a new method for recording spatially incoherent common-path off-axis color digital holograms. We present the theoretical and experimental evidence to demonstrate an incoherent common-path off-axis color digital holographic (ICOCH) system capable of capturing information from three-dimensional color objects under incoherent illumination, both in transmission and reflection modes. Fresnel incoherent correlation holography (FINCH), a common-path system, is a frequently used incoherent holography technique...
February 20, 2018: Applied Optics
https://www.readbyqxmd.com/read/29468770/pessary-for-preterm-birth-prevention-in-twin-pregnancy-with-short-cervix-3-year-follow-up-study
#2
Janneke van 't Hooft, Johanna H van der Lee, Brent C Opmeer, Aleid G van Wassenaer-Leemhuis, Anneloes L van Baar, Dick J Bekedam, Leonie J P Steenis, Sophie Liem, Ewoud Schuit, Cuny Cuijpers, Elise Bleeker, Margot E Vinke, Noor Simons, Irene M de Graaf, Ben Willem J Mol, Cornelieke van de Beek
OBJECTIVE: We recently found in a randomized clinical trial (ProTWIN) that cervical pessary prevented preterm birth and improved neonatal outcome in women with a multiple pregnancy and a cervical length (CL) <38mm. In this follow-up study we evaluated long-term developmental outcomes in the offspring of these women at three years corrected age. METHODS: We conducted a follow-up study of the ProTWIN trial, a trial in which between 2009 and 2012 asymptomatic women with a multiple pregnancy had been randomized to pessary or no pessary...
February 22, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29467518/is-umbilical-coiling-genetically-determined
#3
Nina K Ayala, Linda M Ernst, Emily S Miller
OBJECTIVE: Abnormal umbilical cord coiling is associated with adverse perinatal outcomes; however, the etiology of the umbilical coiling pattern is poorly understood. STUDY DESIGN: Retrospective cohort of all twin deliveries >20 weeks in 2014. Pregnancies were dichotomized by chorionicity and the umbilical coiling index (UCI) and placental cord insertion location were compared. In cases with one or both cords hypercoiled, the direction and pattern of coiling were compared by chorionicity...
February 21, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29467259/structural-origins-of-coloration-in-the-spider-phoroncidia-rubroargentea-berland-1913-araneae-theridiidae-from-madagascar
#4
Sarah Kariko, Jaakko V I Timonen, James C Weaver, Dvir Gur, Carolyn Marks, Leslie Leiserowitz, Mathias Kolle, Ling Li
This study investigates the structural basis for the red, silver and black coloration of the theridiid spider, Phoroncidia rubroargentea (Berland, 1913) from Madagascar. Specimens of this species can retain their colour after storage in ethanol for decades, whereas most other brightly pigmented spider specimens fade under identical preservation conditions. Using correlative optical, structural and chemical analysis, we identify the colour-generating structural elements and characterize their optical properties...
February 2018: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29467101/ultrasound-screening-for-complications-in-twin-pregnancy
#5
Rosemary Townsend, Asma Khalil
In the decades since the introduction of ultrasound into routine obstetric practice, the advantages of ultrasound have moved beyond the simple ability to identify multiple pregnancies antenatally to the possibility of screening them for fetal anomalies, pre-eclampsia, preterm birth, and the complications specific to monochorionic pregnancies. Screening studies have often excluded twins because physiological differences impact on the validity and sensitivity of the screening tests in routine use in singletons, and therefore, the evidence of screening performance in multiple pregnancy lags behind the evidence from singleton pregnancies...
February 18, 2018: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29465765/the-role-of-general-anesthesia-on-traits-of-neurodevelopmental-disorders-in-a-swedish-cohort-of-twins
#6
Albert Castellheim, Sebastian Lundström, Mattias Molin, Ralf Kuja-Halkola, Carina Gillberg, Christopher Gillberg
BACKGROUND: The role of general anesthetics as a risk factor for possible neurodevelopmental disorders (NDDs) in humans is unresolved. The investigation of the role of anesthetics in the development of postgeneral anesthesia (anesthesia onward) NDDs has proven to be complicated, partly because of the inherent confounding in clinical cohort studies, and partly by the fact that anesthetics are only one part in the complex process of anesthesia-surgery. METHODS: Utilizing the Swedish databases Child and Adolescent Twins Study in Sweden (CATSS) and National Patient Register (NPR), we investigated twins discordant for anesthesia, born between 1997 and 2004 for traits of NDDs...
February 21, 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29462956/preparation-of-novel-homodimers-derived-from-cytotoxic-isoquinolinequinones-a-twin-drug-approach
#7
Juana Andrea Ibacache, Judith Faundes, Margarita Montoya, Sophia Mejías, Jaime A Valderrama
The synthesis of five novel homodimers is reported based on the anilinoisoquinolinequinone scaffold. In these twin-drug derivatives, two units of the anilinoquinone pharmacophores are linked through a methylene spacer. The formation of dimers was achieved by reaction of isoquinolinequinones with 4, 4'-diaminodiphenylmethane via a sequence of two oxidative amination reactions. A preliminary in vitro screening of the homodimers reveals moderate to high cytotoxic activities against MDA-MB-21 breast adenocarcinoma and B16-F10 murine metastatic melanoma cell lines...
February 16, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29462812/survival-rate-without-brain-abnormalities-on-postnatal-ultrasonography-among-monochorionic-twins-after-fetoscopic-laser-photocoagulation-for-selective-intrauterine-growth-restriction-with-concomitant-oligohydramnios
#8
Keisuke Ishii, Seiji Wada, Mayumi Takano, Masahiko Nakata, Takeshi Murakoshi, Haruhiko Sago
INTRODUCTION: We aimed to clarify the survival rate without brain abnormalities (BA) after fetoscopic laser photoco-agulation (FLP) for monochorionic diamniotic twin gestations (MCDA) with selective intrauterine growth restriction (sIUGR) accompanied by abnormal umbilical artery (UA) Doppler waveforms and isolated oligohydramnios in the sIUGR twin. MATERIALS AND METHODS: This retrospective study included 52 cases that underwent FLP. The main outcome was survival rate without BA of the twins at age 28 days...
February 20, 2018: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/29462633/improved-stability-of-tb-drug-fixed-dose-combination-using-isoniazid-caffeic-acid-and-vanillic-acid-cocrystal
#9
Battini Swapna, M K Chaitanya Mannava, Ashwini Nangia
The classic FDC of four TB drugs, namely Rifampicin (RIF), Isoniazid (INH), Pyrazinamide (PZA) and Ethambutol Dihydrochloride (EDH) has the twin issues of physical stability and rifampicin cross-reaction in the 4FDC. The major reason for these quality issues is the interaction between RIF and INH to yield isonicotinyl hydrazone (HYD) in drug tablets. Pharmaceutical cocrystals of INH with caffeic acid (PZA + EDH + RIF + INH-CFA cocrystal) and vanillic acid (PZA + EDH + RIF + INH-VLA cocrystal) are able to stabilize the FDC formulation compared to the reference batch (PZA + EDH + RIF + INH)...
February 17, 2018: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29462630/pitfalls-in-assessing-chorioamnionicity-novel-observations-and-literature-review
#10
REVIEW
Jing Lu, Yvonne Kwun Yue Cheng, Yuen Ha Ting, Kwok Ming Law, Tak Yeung Leung
Accurate diagnosis of chorioamnionicity in multiple pregnancies is the key to appropriate clinical management of multiple gestation. Although prenatal ultrasound assessment of chorioamnionicity is well established and highly accurate if performed in early pregnancy, exceptions and artifacts arise from anatomic variations in multiple pregnancies and unusual sonographic features do exist. We have summarized our own experiences and reports from the literature on these pitfalls as follows: (1) Discordant fetal sex in monochorionic pregnancies due to sex chromosome abnormalities, genital malformation in one fetus, or dizygotic twins forming a monochorionic placenta; (2) Separate placental masses in monochorionic pregnancies due to bipartite placenta; (3) False negative and false positive λ sign can arise for various reasons, and in partial monochorionic / dichorionic placentas both T and λ sign may co-exist; (4) Intrauterine synechia appearing as a thick and echogenic intrauterine septum may lead to erroneous diagnosis of dichorionic twins; (5) Errors in ascertaining amnionicity by the visualization of thin inter-twin amniotic membranes and the number of yolk sacs...
February 17, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29462321/discordant-umbilical-cord-drug-testing-results-in-monozygotic-twins
#11
Amy Alexander, Liaqat Abbas, Mary Jones, Joseph Jones, Douglas Lewis, Adam Negrusz
Our laboratory received segments of umbilical cord that originated from identical twins for routine toxicology analysis. The specimens were analyzed multiple times by liquid chromatography tandem mass spectrometry. The umbilical cord from newborn #1 was positive for hydromorphone only (1.06 ng/g), and the umbilical cord from newborn #2 was positive for hydromorphone (0.81 ng/g) and benzoylecgonine (5.41 ng/g). The hydromorphone results are consistent with maternal administration of hydromorphone; however, the cause of the discrepant benzoylecgonine results in the umbilical cords from the identical twins is unknown...
February 15, 2018: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/29461973/mid-pregnancy-cervical-length-as-a-risk-factor-for-cesarean-section-in-women-with-twin-pregnancies
#12
Su Jin Sung, Seung Mi Lee, Sohee Oh, Joo Hee Choi, Jee Yoon Park, Byoung Jae Kim, Joon Ho Lee, Chan-Wook Park, Joong Shin Park, Jong Kwan Jun
OBJECTIVE: It is well known that a short cervix at mid-pregnancy is a risk factor for spontaneous preterm birth in both singleton and twin gestations. Recent evidence also suggests that a long cervix at mid-pregnancy is a predictor of the risk of cesarean section (C/S) in singleton gestation. The purpose of this study was to determine whether a long cervix at mid-pregnancy was associated with an increased risk of C/S in women with twin pregnancies. METHODS: We enrolled 746 women pregnant with twins whose cervical length was measured by trans-vaginal ultrasonography at a mean of 22 weeks of gestation and who delivered in our institution...
February 20, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29461481/a-dislocation-scale-characterization-of-the-evolution-of-deformation-microstructures-around-nanoindentation-imprints-in-a-tial-alloy
#13
Antoine Guitton, Hana Kriaa, Emmanuel Bouzy, Julien Guyon, Nabila Maloufi
In this work, plastic deformation was locally introduced at room temperature by nanoindentation on a γ-TiAl-based alloy. Comprehensive analyses of microstructures were performed before and after deformation. In particular, the Burgers vectors, the line directions, and the mechanical twinning systems were studied via accurate electron channeling contrast imaging. Accommodation of the deformation are reported and a scenario is proposed. All features help to explain the poor ductility of the TiAl-based alloys at room temperature...
February 20, 2018: Materials
https://www.readbyqxmd.com/read/29460615/precursor-receptor-interactions-in-the-twin-arginine-protein-transport-pathway-probed-with-a-new-receptor-complex-preparation
#14
Marta Wojnowska, Joseph Gault, Shee Chien Yong, Carol V Robinson, Ben C Berks
The twin arginine translocation (Tat) system moves folded proteins across the cytoplasmic membrane of bacteria and the thylakoid membrane of plant chloroplasts. Signal peptide-bearing substrates of the Tat pathway (precursor proteins) are recognised at the membrane by the TatBC receptor complex. The only established preparation of the TatBC complex uses the detergent digitonin, which is unsuitable for biophysical analysis. Here we show that the detergent glyco-diosgenin (GDN) can be used in place of digitonin to isolate homogenous TatBC complexes that bind precursor proteins with physiological specificity...
February 20, 2018: Biochemistry
https://www.readbyqxmd.com/read/29460287/chromosomal-aberrations-and-cnvs-in-twin-fetuses-with-cardiovascular-anomalies-comparison-between-monochorionic-diamniotic-and-dichorionic-diamniotic-twins
#15
Yi Zhang, Linhuan Huang, Xuan Huang, Zhiming He, Shaobin Lin, Ye Wang, Lin Li, Yanmin Luo, Qun Fang
OBJECTIVE: To investigate the types of cardiovascular anomalies and the results of invasive prenatal diagnosis in twin fetuses. METHODS: A total of 298 fetuses in 149 twin pairs were enrolled, in which 1 or 2 fetuses of a twin pair had cardiovascular anomalies. Prenatal diagnosis was performed on 290 fetuses of 149 twin pairs, including 150 monochorionic diamniotic (MCDA) fetuses (79 pairs) and 140 dichorionic diamniotic (DCDA) fetuses (70 pairs). G-banding karyotyping and/or chromosomal microarray analysis (CMA) were performed...
February 19, 2018: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29460062/non-syndromic-single-suture-craniosynostosis-in-triplets
#16
David Chesler, Richard Bram, Prince Antwi, Andrew T Timberlake, Michael L DiLuna, Kristopher T Kahle
INTRODUCTION: Craniosynostosis is the premature fusion of one or more cranial sutures. The cause of non-syndromic craniosynostosis has been attributed to a complex interaction among genetic, epigenetic, and environmental factors. Increased concordance rates in monozygotic twins support a genetic etiology while a concordance rate less than 100% suggests environmental and/or epigenetic influences. Here, we describe the first reported occurrence of all three children in a triplet set with non-syndromic single-suture craniosynostosis...
February 19, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29459586/risk-factors-and-immediate-neonatal-outcome-of-multiple-pregnancies-in-a-scanu-of-a-tertiary-care-hospital-bangladesh
#17
M N Islam, T Tazmin, M Siddika, M A Hossain, M A Ali, M K Bhuiyan
Multiple pregnancies are a significant risk factor for maternal and perinatal morbidity due to inherent biological risks. The present study was aimed to determine the risk factors and to evaluate the immediate neonatal outcome of multiple pregnancies. This descriptive observational study was conducted in the newly established Special Care Neonatal Unit (SCANU) of Mymensingh Medical College Hospital (MMCH), Bangladesh from January 2015 to March 2015. Total 86 newborns of multiple pregnancies who were admitted during the study period were included in the study...
January 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29459401/low-dose-gonadotropin-induction-of-ovulation-in-anovulatory-women-still-needed-in-the-age-of-ivf
#18
Davinia White, Kate Hardy, Suzannah Lovelock, Stephen Franks
Low-dose, step-up gonadotropin is the treatment of choice for women with PCOS who have not conceived after anti-estrogen treatment, and as an effective alternative to pulsatile GnRH in women with hypogonadotropic hypogonadism (HH). There has been, however, no large-scale, comparative study between the two groups using low-dose gonadotropins. Here we performed a retrospective, comparative analysis, in a single clinic database, of efficacy and safety of induction of ovulation using low-dose gonadotropins in 364 Women with PCOS and 80 women with HH...
February 19, 2018: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/29459249/associations-between-social-capital-and-depression-a-study-of-adult-twins
#19
Hannah Cohen-Cline, Shirley Aa Beresford, Wendy Barrington, Ross Matsueda, Jon Wakefield, Glen E Duncan
Social capital is associated with depression independently of individual-level risk factors. We used a sample of 1586 same-sex twin pairs to test the association between seven measures of social capital and two related measures of neighborhood characteristics with depressive symptoms accounting for uncontrolled selection factors (i.e., genetics and shared environment). All measures of cognitive social capital and neighborhood characteristics were associated with less depressive symptoms in between-twin analysis...
February 16, 2018: Health & Place
https://www.readbyqxmd.com/read/29458912/early-fetal-reduction-to-twin-versus-prophylactic-cervical-cerclage-for-triplet-pregnancies-conceived-with-assisted-reproductive-techniques
#20
Mohamed Sayed Abdelhafez, Mahmoud Mohamed Abdelrazik, Ahmed Badawy
OBJECTIVE: To compare the obstetric outcomes of triplet gestations managed by early fetal reduction to twins with those managed by prophylactic cervical cerclage in women conceived with assisted reproductive techniques (ART). MATERIALS AND METHODS: Retrospective study of the pregnancy and neonatal outcomes of trichorionic triplet gestations achieved by ART and managed either by early transvaginal fetal reduction to twins (n = 53) or by prophylactic placement of cervical cerclage (n = 65)...
February 2018: Taiwanese Journal of Obstetrics & Gynecology
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