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https://www.readbyqxmd.com/read/27926431/the-oral-microbiome-in-health-and-its-implication-in-oral-and-systemic-diseases
#1
B Sampaio-Maia, I M Caldas, M L Pereira, D Pérez-Mongiovi, R Araujo
The oral microbiome can alter the balance between health and disease, locally and systemically. Within the oral cavity, bacteria, archaea, fungi, protozoa, and viruses may all be found, each having a particular role, but strongly interacting with each other and with the host, in sickness or in health. A description on how colonization occurs and how the oral microbiome dynamically evolves throughout the host's life is given. In this chapter the authors also address oral and nonoral conditions in which oral microorganisms may play a role in the etiology and progression, presenting the up-to-date knowledge on oral dysbiosis as well as the known underlying pathophysiologic mechanisms involving oral microorganisms in each condition...
2016: Advances in Applied Microbiology
https://www.readbyqxmd.com/read/27918898/roles-of-l-type-calcium-channels-cav1-2-and-the-distal-c-terminus-dct-in-differentiation-and-mineralization-of-rat-dental-apical-papilla-stem-cells-rscaps
#2
Qianqian Gao, Jianping Ge, Yanqin Ju, Changsheng Li, Jian Gao, Meisheng Wu, Shouliang Zhao
OBJECTIVE: Voltage-gated inward Ca(2+) currents (ICa) are triggered by cell depolarization and commonly produce transient increases in the cytoplasmic free Ca(2+) concentration. The CaV1.2 distal C-terminus is susceptible to proteolytic cleavage, which yields a truncated CaV1.2 subunit and a cleaved C-terminal fragment (CCt or DCT). Stem cells from the apical papilla (SCAPs) has a capacity for differentiation into the odontoblastic-like cells in vitro and dentin forming in vivo, which makes SCAPs advantages in tissue engineering and regenerative endodontic...
November 4, 2016: Archives of Oral Biology
https://www.readbyqxmd.com/read/27917512/a-re-audit-of-the-technical-quality-of-undergraduate-root-canal-treatment-after-the-introduction-of-new-technology-and-teaching-practices
#3
A Donnelly, D Coffey, H F Duncan
AIM: To revaluate through re-audit the technical quality of undergraduate non-surgical root canal treatment (RCTx) in a dental teaching hospital as a result of recommended changes to teaching practices. METHODOLOGY: The technical quality of undergraduate RCTx was evaluated radiographically after educational changes and the mandatory introduction of new technologies (nickel-titanium files, apex locators, greater-taper gutta-percha points) in 182 root canals. Evaluation was based on 4 criteria; presence of voids, root canal filling termination (0-2mm of radiographic apex), all roots filled and the prepared canal contained the original anatomy...
December 5, 2016: International Endodontic Journal
https://www.readbyqxmd.com/read/27912822/endodontics-at-the-verge-of-new-era-driven-by-biological-innovation
#4
EDITORIAL
Mo K Kang
No abstract text is available yet for this article.
January 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/27912820/modern-endodontic-microsurgery-concepts-a-clinical-update
#5
REVIEW
Spyros Floratos, Syngcuk Kim
Increased use of the surgical operating microscope in endodontic surgery has elucidated many shortcomings of previous techniques and along with microsurgical instruments and new more biologically acceptable root-end filling materials has started the new microsurgical era in surgical endodontics. Endodontic microsurgery is a minimally invasive technique that results in less postoperative pain and edema and faster wound healing. It offers a significantly higher success rate than traditional apical surgery technique...
January 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/27912819/endodontic-treatment-outcomes
#6
REVIEW
Nadia Chugal, Sanjay M Mallya, Bill Kahler, Louis M Lin
The primary goal of conventional endodontic treatment is prevention and/or elimination of apical periodontitis for both mature permanent teeth and immature teeth with an open apex. Besides these goals, the objectives of endodontic treatment of immature teeth include preservation of pulp vitality and often further root maturation. Robust criteria for outcome assessment are an essential determinant for any measure of treatment success for both mature and immature teeth.
January 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/27912817/molecular-mechanisms-of-apical-periodontitis-emerging-role-of-epigenetic-regulators
#7
REVIEW
Shebli Mehrazarin, Abdullah Alshaikh, Mo K Kang
Conventional root canal therapies yield high success rates. The treatment outcomes are negatively affected by the presence of apical periodontitis (AP), which reflects active root canal infection and inflammatory responses. Also, cross-sectional studies revealed surprisingly high prevalence of AP in the general population, especially in those with prior endodontic treatments. Hence, AP is an ongoing disease entity in endodontics that needs further understanding of the pathogenesis and disease progression. The current Chapter will discuss the basic mechanisms of AP with emphasis on emerging role of epigenetic regulators in regulation of inflammatory mediators...
January 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/27912815/regenerative-endodontics-by-cell-homing
#8
REVIEW
Ling He, Juan Zhong, Qimei Gong, Bin Cheng, Sahng G Kim, Junqi Ling, Jeremy J Mao
Apical revascularization (AR) and platelet-rich plasma have been used to restore dental pulp vitality in infected immature permanent teeth. Two regenerative therapies are cell transplantation and cell homing. This article updates and benchmarks these therapies with cell homing. A case report concluded that AR increased root length; however, quantitative and statistical assessments disproved this. Regenerative endodontic therapies require prospective clinical trials demonstrating safety and efficacy. These therapies are intrinsically susceptible to procedural and patient variations...
January 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/27912814/biological-molecules-for-the-regeneration-of-the-pulp-dentin-complex
#9
REVIEW
Sahng G Kim
Regenerative endodontic treatment has yielded excellent clinical outcomes, but only several animal studies have shown the robust regeneration of the pulp-dentin complex. The biological molecules, if properly delivered, can enkindle regeneration of dental pulp and dentin rather than repair with tissues of periodontal origin. This review details the biological significance of regenerating the pulp-dentin complex, the effects of biological cues in pulp regeneration, and the delivery strategies of biological molecules to enhance the outcomes of regenerative endodontic therapy...
January 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/27912813/regenerative-endodontic-procedures-clinical-outcomes
#10
REVIEW
Anibal Diogenes, Nikita B Ruparel
Immature teeth are at risk for pulp necrosis, resulting in arrested root development and poor long-term prognosis. There is growing evidence that regenerative endodontic procedures promote desirable clinical outcomes. Despite significant advances in the field of regenerative endodontics and acceptable clinical outcomes, current evidence suggests that the tissues formed following currently used procedures do not completely recapitulate the former pulp-dentin complex. Further research is needed to identify prognostic factors and predictors of successful outcomes and to develop different treatment strategies to better predictably achieve all identified clinical outcomes, while favoring tissue formation that more closely resembles the pulp-dentin complex...
January 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/27912812/endodontic-microbiology-and-pathobiology-current-state-of-knowledge
#11
REVIEW
Ashraf F Fouad
Newer research tools and basic science knowledge base have allowed the exploration of endodontic diseases in the pulp and periapical tissues in novel ways. The use of next generation sequencing, bioinformatics analyses, genome-wide association studies, to name just a few of these innovations, has allowed the identification of hundreds of microorganisms and of host response factors. This review addresses recent advances in endodontic microbiology and the host response and discusses the potential for future innovations in this area...
January 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/27905673/single-versus-multiple-visits-for-endodontic-treatment-of-permanent-teeth
#12
REVIEW
Maddalena Manfredi, Lara Figini, Massimo Gagliani, Giovanni Lodi
BACKGROUND: Root canal treatment (RoCT), or endodontic treatment, is a common procedure in dentistry. The main indications for RoCT are irreversible pulpitis and necrosis of the dental pulp caused by carious processes, tooth cracks or chips, or dental trauma. Successful RoCT is characterised by an absence of symptoms (i.e. pain) and clinical signs (i.e. swelling and sinus tract) in teeth without radiographic evidence of periodontal involvement (i.e. normal periodontal ligament). The success of RoCT depends on a number of variables related to the preoperative condition of the tooth, as well as the endodontic procedures...
December 1, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27901225/external-cervical-resorption-diagnostic-and-treatment-tips
#13
Alberto Consolaro
External cervical resorption is caused, almost exclusively, by dental trauma - especially those characterized by concussion - and is a dental disease to be diagnosed and treated accurately by endodontists. However, the vast majority of the cases is initially diagnosed by an orthodontist, due to the imaging possibilities in standardized documentations. Among the causes of external cervical resorption, it is common to mistakenly attribute it to orthodontic treatment, traumatic occlusion or even to chronic inflammatory periodontal disease...
September 2016: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/27898727/biological-markers-for-pulpal-inflammation-a-systematic-review
#14
Dan-Krister Rechenberg, Johnah C Galicia, Ove A Peters
BACKGROUND AND OBJECTIVE: Pulpitis is mainly caused by an opportunistic infection of the pulp space with commensal oral microorganisms. Depending on the state of inflammation, different treatment regimes are currently advocated. Predictable vital pulp therapy depends on accurate determination of the pulpal status that will allow repair to occur. The role of several players of the host response in pulpitis is well documented: cytokines, proteases, inflammatory mediators, growth factors, antimicrobial peptides and others contribute to pulpal defense mechanisms; these factors may serve as biomarkers that indicate the status of the pulp...
2016: PloS One
https://www.readbyqxmd.com/read/27898180/apical-negative-pressure-irrigation-versus-syringe-irrigation-a-systematic-review-of-cleaning-and-disinfection-of-the-root-canal-system
#15
REVIEW
E Konstantinidi, Z Psimma, L E Chávez de Paz, C Boutsioukis
The aim of this study was to systematically review and critically analyse the published data on the treatment outcome (primary outcome) and on the cleaning and disinfection of root canals (secondary outcomes) achieved by negative pressure irrigation as compared to syringe irrigation. An electronic search was conducted in EMBASE, LILACS, Pubmed, SciELO, Scopus, and Web of Knowledge using both free-text keywords and controlled vocabulary. Additional studies were sought through hand-searching of endodontic journals and of the relevant chapters of endodontic textbooks...
November 28, 2016: International Endodontic Journal
https://www.readbyqxmd.com/read/27895867/detection-of-second-mesiobuccal-canals-in-maxillary-first-molars-using-a-new-angle-of-cone-beam-computed-tomography
#16
Ali Murat Aktan, Cihan Yildirim, Emre Culha, Erhan Demir, Mehmet Ertugrul Ciftci
BACKGROUND: The localization of the additional canal orifice is one of the primary factors influencing the success of endodontic treatment. To deal with this problem, several techniques that each have their own advantages and disadvantages have been discussed in the literature. OBJECTIVES: The aim of the present in vitro study was to review a new approach to localizing second mesiobuccal (MB2) canals in maxillary first molars using cone beam computed tomography (CBCT)...
October 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27895347/comparison-of-fracture-and-deformation-in-the-rotary-endodontic-instruments-protaper-versus-k-3-system
#17
Sana Ehsen Nagi, Farhan Raza Khan, Munawar Rahman
This experimental study was done on extracted human teeth to compare the fracture and deformation of the two rotary endodontic files system namely K-3 and Protapers. It was conducted at the dental clinics of the Aga Khan University Hospital, Karachi, A log of file deformation or fracture during root canal preparation was kept. The location of fracture was noted along with the identity of the canal in which fracture took place. The fracture in the two rotary systems was compared. SPSS 20 was used for data analysis...
March 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27892627/withdrawn-pulp-management-for-caries-in-adults-maintaining-pulp-vitality
#18
REVIEW
Hiroshi Miyashita, Helen V Worthington, Alison Qualtrough, Alphons Plasschaert
BACKGROUND: There is a range of treatment options for the management of the pulp in extensively decayed teeth. These include direct and indirect pulp capping, pulpotomy or pulpectomy. If the tooth is symptomatic or if there are periapical bone changes, then endodontic treatment is required. However, if the tooth is asymptomatic but the caries is extensive, there is no consensus as to the best method of management. In addition, there has been a recent move towards using alternative materials and methods such as the direct or indirect placement of bonding agents and mineral trioxide aggregate...
November 28, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27892626/withdrawn-root-canal-posts-for-the-restoration-of-root-filled-teeth
#19
REVIEW
Marc Bolla, Michele Muller-Bolla, Cybele Borg, Laurence Lupi-Pegurier, Olivier Laplanche, Eric Leforestier
BACKGROUND: The foundation for the reconstruction of endodontically-treated teeth can be provided by a metal or a non-metal post and core system but no guidelines exist for choosing one or the other in particular clinical cases. OBJECTIVES: To assess the effectiveness of different post and core systems for the restoration of endodontically-treated teeth. The primary objective of this review was to compare the clinical failure rates of the different types of posts...
November 28, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27891569/chair-side-generated-posterior-monolithic-lithium-disilicate-crowns-clinical-survival-after-6%C3%A2-years
#20
Angelika Rauch, Sven Reich, Oliver Schierz
OBJECTIVES: The objective of this prospective clinical study was to evaluate the clinical performance of chair-side generated monolithic lithium disilicate crowns after 72 months. MATERIALS AND METHODS: Forty-one posterior full contour crowns made of lithium disilicate ceramic were inserted in 34 patients with a chair-side CAD/CAM technique. One crown per patient was randomly selected for evaluation at baseline, 6, 12, 24, 36, 48, 60 and 72 months according to the modified US Public Health Service criteria...
November 28, 2016: Clinical Oral Investigations
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