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https://www.readbyqxmd.com/read/28449282/organotitania-based-nanostructures-as-a-suitable-platform-for-the-implementation-of-binary-ternary-and-fuzzy-logic-systems
#1
Andrzej Blachecki, Justyna Mech-Piskorz, Marta Gajewska, Krzysztof Mech, Kacper Pilarczyk, Konrad Szacilowski
Titanium dioxide nanocomposites were synthesized in hierarchical architectures with the use of 1,4-dihydroxyanthraquinone photosensitizer. In the first step, the dye was either incorporated into the TiO2 core or adsorbed on its surface. In the subsequent phase, both structures were covered with an outer layer of titanium dioxide. The structure, morphology, aggregation, spectroscopic and electrochemical properties of the synthesized TiO2-based materials are presented with a special emphasis on the photosensitization and the photocurrent switching phenomena which are also discussed within the context of the optical logic gates implementation and fuzzy logic systems operation...
April 27, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28449257/the-development-and-application-of-random-match-probabilities-to-firearm-and-toolmark-identification
#2
John E Murdock, Nicholas D K Petraco, John I Thornton, Michael T Neel, Todd J Weller, Robert M Thompson, James E Hamby, Eric R Collins
The field of firearms and toolmark analysis has encountered deep scrutiny of late, stemming from a handful of voices, primarily in the law and statistical communities. While strong scrutiny is a healthy and necessary part of any scientific endeavor, much of the current criticism leveled at firearm and toolmark analysis is, at best, misinformed and, at worst, punditry. One of the most persistent criticisms stems from the view that as the field lacks quantified random match probability data (or at least a firm statistical model) with which to calculate the probability of a false match, all expert testimony concerning firearm and toolmark identification or source attribution is unreliable and should be ruled inadmissible...
May 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28449114/neuro-symbolic-representation-learning-on-biological-knowledge-graphs
#3
Mona Alshahrani, Mohammed Asif Khan, Omar Maddouri, Akira R Kinjo, Núria Queralt-Rosinach, Robert Hoehndorf
Motivation: Biological data and knowledge bases increasingly rely on Semantic Web technologies and the use of knowledge graphs for data integration, retrieval and federated queries. In the past years, feature learning methods that are applicable to graph-structured data are becoming available, but have not yet widely been applied and evaluated on structured biological knowledge. Results: We develop a novel method for feature learning on biological knowledge graphs...
April 25, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28446207/memory-is-preserved-in-older-adults-taking-at1-receptor-blockers
#4
Jean K Ho, Daniel A Nation
BACKGROUND: Prior work suggests that some but not all antihypertensive treatments may benefit cognition and risk for Alzheimer's disease, independent of stroke. Angiotensin II receptor blockers (ARBs) have been highlighted as one antihypertensive drug class that may confer greatest benefit. METHODS: The participants comprised 1626 nondemented adults, aged 55-91 years, recruited from Alzheimer's Disease Neuroimaging Initiative sites. Three groups were compared: ARB users (HTN-ARBs), other antihypertensive drug users (HTN-Other), and normotensives...
April 26, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28446138/assessing-the-complexity-of-interventions-within-systematic-reviews-development-content-and-use-of-a-new-tool-icat_sr
#5
Simon Lewin, Maggie Hendry, Jackie Chandler, Andrew D Oxman, Susan Michie, Sasha Shepperd, Barnaby C Reeves, Peter Tugwell, Karin Hannes, Eva A Rehfuess, Vivien Welch, Joanne E Mckenzie, Belinda Burford, Jennifer Petkovic, Laurie M Anderson, Janet Harris, Jane Noyes
BACKGROUND: Health interventions fall along a spectrum from simple to more complex. There is wide interest in methods for reviewing 'complex interventions', but few transparent approaches for assessing intervention complexity in systematic reviews. Such assessments may assist review authors in, for example, systematically describing interventions and developing logic models. This paper describes the development and application of the intervention Complexity Assessment Tool for Systematic Reviews (iCAT_SR), a new tool to assess and categorise levels of intervention complexity in systematic reviews...
April 26, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28444045/coap-and-sus-regionalization-the-various-implementation-patterns-in-the-brazilian-states
#6
Assis Mafort Ouverney, José Mendes Ribeiro, Marcelo Rasga Moreira
This paper analyzes the implementation process of the Public Action Organizational Contract (Coap) and its impacts on state agendas of SUS regionalization, comparing the different institutional reactions of the states to the strategy proposed by Decree 7.508/11. The comparison of developing dynamics of state agendas took as reference a normative baseline structured in eight strategic political-institutional moments in the implementation of the Coap in accordance with the logic defined in Decree 7.508/11. We collected data through a questionnaire containing 35 questions (1 open, 25 closed and 9 mixed) and extensive documentary research in 2013 and 2014 in all states, except for the Federal District...
April 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28442742/non-volatile-logic-gates-based-on-planar-hall-effect-in-magnetic-films-with-two-in-plane-easy-axes
#7
Sangyeop Lee, Seul-Ki Bac, Seonghoon Choi, Hakjoon Lee, Taehee Yoo, Sanghoon Lee, Xinyu Liu, M Dobrowolska, Jacek K Furdyna
We discuss the use of planar Hall effect (PHE) in a ferromagnetic GaMnAs film with two in-plane easy axes as a means for achieving novel logic functionalities. We show that the switching of magnetization between the easy axes in a GaMnAs film depends strongly on the magnitude of the current flowing through the film due to thermal effects that modify its magnetic anisotropy. Planar Hall resistance in a GaMnAs film with two in-plane easy axes shows well-defined maxima and minima that can serve as two binary logic states...
April 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28442452/homestyles-a-web-based-childhood-obesity-prevention-program-for-families-with-preschool-children-protocol-for-a-randomized-controlled-trial
#8
Carol Byrd-Bredbenner, Jennifer Martin-Biggers, Mallory Koenings, Virginia Quick, Nobuko Hongu, John Worobey
BACKGROUND: The home environment is where young children spend most of their time, and is critically important to supporting behaviors that promote health and prevent obesity. However, the home environment and lifestyle patterns remain understudied, and few interventions have investigated parent-led makeovers designed to create home environments that are supportive of optimal child health and healthy child weights. OBJECTIVE: The aim of the HomeStyles randomized controlled trial (RCT) is to determine whether the Web-based HomeStyles intervention enables and motivates parents to shape the weight-related aspects of their home environments and lifestyle behavioral practices (diet, exercise, and sleep) to be more supportive of their preschool children's optimal health and weight...
April 25, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28442393/progesterone-receptors-pr-mediate-stat-actions-pr-and-prolactin-receptor-signaling-crosstalk-in-breast-cancer-models
#9
Katherine A Leehy, Thu H Truong, Laura J Mauro, Carol A Lange
Estrogen is the major mitogenic stimulus of mammary gland development during puberty wherein ER signaling acts to induce abundant PR expression. PR signaling, in contrast, is the primary driver of mammary epithelial cell proliferation in adulthood. The high circulating levels of progesterone during pregnancy signal through PR, inducing expression of the prolactin receptor (PRLR). Cooperation between PR and prolactin (PRL) signaling, via regulation of downstream components in the PRL signaling pathway including JAKs and STATs, facilitates the alveolar morphogenesis observed during pregnancy...
April 22, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28441860/smart-luminescent-coordination-polymers-towards-multi-mode-logic-gates-time-resolved-tribochromic-and-excitation-dependent-fluorescence-phosphorescence-emission
#10
Yongsheng Yang, Ke-Zhi Wang, Dongpeng Yan
In this work, we propose that lanthanide cations (such as Eu3+ and Tb3+) doped long-afterglow coordination polymer (CP) can be an effective way to design multi-mode optical logic gates based on their tunable fluorescence/phosphorescence transformation and state-dependent emission. First, multi-color and white-light luminescence across the blue/green/yellow/red visible regions can be obtained by balancing the co-doping ratio of Eu3+/Tb3+ cations and suitable excitations. Additionally, new mechanochromic Eu-Cd-CP was developed based on the mechanism of change in structural symmetry...
April 26, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28440550/political-drivers-of-epidemic-response-foreign-healthcare-workers-and-the-2014-ebola-outbreak
#11
Daniel Nohrstedt, Erik Baekkeskov
This study demonstrates that countries responded quite differently to calls for healthcare workers (HCWs) during the Ebola epidemic in West Africa in 2014. Using a new dataset on the scale and timing of national pledges and the deployment of HCWs to states experiencing outbreaks of the virus disease (principally, Guinea, Liberia, and Sierra Leone), it shows that few foreign nations deployed HCWs early, some made pledges but then fulfilled them slowly, and most sent no HCWs at all. To aid understanding of such national responses, the paper reviews five theoretical perspectives that offer potentially competing or complementary explanations of foreign government medical assistance for international public health emergencies...
April 25, 2017: Disasters
https://www.readbyqxmd.com/read/28440273/active-matter-logic-for-autonomous-microfluidics
#12
Francis G Woodhouse, Jörn Dunkel
Chemically or optically powered active matter plays an increasingly important role in materials design, but its computational potential has yet to be explored systematically. The competition between energy consumption and dissipation imposes stringent physical constraints on the information transport in active flow networks, facilitating global optimization strategies that are not well understood. Here, we combine insights from recent microbial experiments with concepts from lattice-field theory and non-equilibrium statistical mechanics to introduce a generic theoretical framework for active matter logic...
April 25, 2017: Nature Communications
https://www.readbyqxmd.com/read/28439553/maximizing-the-performance-of-photothermal-actuators-by-combining-smart-materials-with-supplementary-advantages
#13
Tongyu Wang, David Torres, Félix E Fernández, Chuan Wang, Nelson Sepúlveda
The search for higher-performance photothermal microactuators has typically involved unavoidable trade-offs that hinder the demonstration of ubiquitous devices with high energy density, speed, flexibility, efficiency, sensitivity, and multifunctionality. Improving some of these parameters often implies deterioration of others. Photothermal actuators are driven by the conversion of absorbed optical energy into thermal energy, which, by different mechanisms, can produce mechanical displacement of a structure...
April 2017: Science Advances
https://www.readbyqxmd.com/read/28439455/the-evolution-of-logic-circuits-for-the-purpose-of-protein-contact-map-prediction
#14
Samuel D Chapman, Christoph Adami, Claus O Wilke, Dukka B Kc
Predicting protein structure from sequence remains a major open problem in protein biochemistry. One component of predicting complete structures is the prediction of inter-residue contact patterns (contact maps). Here, we discuss protein contact map prediction by machine learning. We describe a novel method for contact map prediction that uses the evolution of logic circuits. These logic circuits operate on feature data and output whether or not two amino acids in a protein are in contact or not. We show that such a method is feasible, and in addition that evolution allows the logic circuits to be trained on the dataset in an unbiased manner so that it can be used in both contact map prediction and the selection of relevant features in a dataset...
2017: PeerJ
https://www.readbyqxmd.com/read/28438115/an-auditory-display-tool-for-dna-sequence-analysis
#15
Mark D Temple
BACKGROUND: DNA Sonification refers to the use of an auditory display to convey the information content of DNA sequence data. Six sonification algorithms are presented that each produce an auditory display. These algorithms are logically designed from the simple through to the more complex. Three of these parse individual nucleotides, nucleotide pairs or codons into musical notes to give rise to 4, 16 or 64 notes, respectively. Codons may also be parsed degenerately into 20 notes with respect to the genetic code...
April 24, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28437965/comparison-between-optical-bistabilities-versus-power-and-frequency-in-a-composite-cavity-atom-system
#16
Zhaoyang Zhang, Danmeng Ma, Jun Liu, Yanyong Sun, Lin Cheng, Ghulam Abbas Khan, Yanpeng Zhang
By making use of the changes in optical properties such as absorption and dispersion around the resonance generated via electromagnetically induced transparency (EIT), we theoretically and experimentally investigate a "∞"-shape optical bistability (OB) versus frequency on the probe transmission with a Λ-shape EIT window in a rubidium atomic ensemble confined in a three-mirror optical ring cavity. Compared to the traditional OB reflected by a hysteresis loop versus power, such newly demonstrated optical bistable behavior (represented by a "∞"-shape non-overlapping region) by scanning probe and cavity detuning can experience dual bistabilities and be more sensitive to the change of experimental parameters...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437920/cmos-integrated-gan-led-array-for-discrete-power-level-stepping-in-visible-light-communications
#17
Alexander D Griffiths, Mohamed Sufyan Islim, Johannes Herrnsdorf, Jonathan J D McKendry, Robert Henderson, Harald Haas, Erdan Gu, Martin D Dawson
We report a CMOS integrated micro-LED array capable of generating discrete optical output power levels. A 16 × 16 array of individually addressable pixels are on-off controlled through parallel logic signals. With carefully selected groups of LEDs driven together, signals suitable for discrete transmission schemes are produced. The linearity of the device is assessed, and data transmission using pulse amplitude modulation (PAM) and orthogonal frequency division multiplexing (OFDM) is performed. Error-free transmission at a symbol rate of 100 MSamples/s is demonstrated with 4-PAM, yielding a data rate of 200 Mb/s...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437086/the-skyrmion-switch-turning-magnetic-skyrmion-bubbles-on-and-off-with-an-electric-field
#18
Marine Schott, Anne Bernand-Mantel, Laurent Ranno, Stéfania Pizzini, Jan Vogel, Hélène Béa, Claire Baraduc, Stéphane Auffret, Gilles Gaudin, Dominique Givord
Nanoscale magnetic skyrmions are considered as potential information carriers for future spintronics memory and logic devices. Such applications will require the control of their local creation and annihilation, which involves so far solutions that are either energy consuming or difficult to integrate. Here we demonstrate the control of skyrmion bubbles nucleation and annihilation using electric field gating, an easily integrable and potentially energetically efficient solution. We present a detailed stability diagram of the skyrmion bubbles in a Pt/Co/oxide trilayer and show that their stability can be controlled via an applied electric field...
April 24, 2017: Nano Letters
https://www.readbyqxmd.com/read/28435459/aptamer-internalization-via-endocytosis-inducing-s-phase-arrest-and-priming-maver-1-lymphoma-cells-for-cytarabine-chemotherapy
#19
Huan Li, Shuanghui Yang, Ge Yu, Liangfang Shen, Jia Fan, Ling Xu, Hedong Zhang, Nianxi Zhao, Zihua Zeng, Tony Hu, Jianguo Wen, Youli Zu
The goal of precision therapy is to efficiently treat cancer without side effects. Aptamers are a class of small ligands composed of single-stranded oligonucleotides that bind to their targets with high affinity and specificity. In this study, we identified an ssDNA aptamer specifically targeting Maver-1 lymphoma cells with high binding affinity (Kd = 70±8 pmol/L). Interestingly, cellular cycle studies revealed that exposure of Maver-1 cells to synthetic aptamers triggered S-phase arrest of 40% of the cells (vs...
2017: Theranostics
https://www.readbyqxmd.com/read/28435283/unlocking-the-black-box-of-practice-improvement-strategies-to-implement-surgical-safety-checklists-a-process-evaluation
#20
Brigid M Gillespie, Kyra Hamilton, Dianne Ball, Joanne Lavin, Therese Gardiner, Teresa K Withers, Andrea P Marshall
BACKGROUND: Compliance with surgical safety checklists (SSCs) has been associated with improvements in clinical processes such as antibiotic use, correct site marking, and overall safety processes. Yet, proper execution has been difficult to achieve. OBJECTIVES: The objective of this study was to undertake a process evaluation of four knowledge translation (KT) strategies used to implement the Pass the Baton (PTB) intervention which was designed to improve utilization of the SSC...
2017: Journal of Multidisciplinary Healthcare
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