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https://www.readbyqxmd.com/read/28527853/influence-of-intracanal-materials-in-vertical-root-fracture-pathway-detection-with-cone-beam-computed-tomography
#1
Kamile Leonardi Dutra, Camila Pachêco-Pereira, Eduardo Antunes Bortoluzzi, Carlos Flores-Mir, Manuel O Lagravère, Márcio Corrêa
INTRODUCTION: Investigating the vertical root fracture (VRF) pathway under different clinical scenarios may help to diagnose this condition properly. We aimed to determine the capability and intrareliability of VRF pathway detection through cone-beam computed tomographic (CBCT) imaging as well as analyze the influence of different intracanal and crown materials. METHODS: VRFs were mechanically induced in 30 teeth, and 4 clinical situations were reproduced in vitro: no filling, gutta-percha, post, and metal crown...
May 17, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28527848/combined-therapy-for-a-rare-case-of-type-iii-dens-invaginatus-in-a-mandibular-central-incisor-with-a-periapical-lesion-a-case-report
#2
Ping Zhang, Xin Wei
Type III dens invaginatus has a complex root canal structure that poses a greater challenge when endodontic treatment is necessary. Type III dens invaginatus rarely affects mandibular central incisors. In this case, we reported a combined therapy of type III dens invaginatus in a mandibular central incisor with a periapical lesion. Cone-beam computed tomographic (CBCT) imaging was used in the diagnosis and management of the unusual anatomy of dens invaginatus. First, the hard tissue of the dens invaginatus was removed using a dental operating microscope...
May 17, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28527481/rethinking-anatomy-how-to-overcome-challenges-of-medical-education-s-evolution
#3
REVIEW
Bruno Guimarães, Luís Dourado, Stanislav Tsisar, José Miguel Diniz, Maria Dulce Madeira, Maria Amélia Ferreira
INTRODUCTION: Due to scientific and technological development, Medical Education has been readjusting its focus and strategies. Medical curriculum has been adopting a vertical integration model, in which basic and clinical sciences coexist during medical instruction. This context favours the introduction of new complementary technology-based pedagogical approaches. Thus, even traditional core sciences of medical curriculum, like Anatomy, are refocusing their teaching/learning paradigm...
February 27, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28526696/visualizing-fundamental-neuronal-computation-for-life-science-students
#4
Alon Korngreen
No abstract text is available yet for this article.
June 1, 2017: Advances in Physiology Education
https://www.readbyqxmd.com/read/28524117/ebutterfly-leveraging-massive-online-citizen-science-for-butterfly-consevation
#5
Kathleen L Prudic, Kent P McFarland, Jeffrey C Oliver, Rebecca A Hutchinson, Elizabeth C Long, Jeremy T Kerr, Maxim Larrivée
Data collection, storage, analysis, visualization, and dissemination are changing rapidly due to advances in new technologies driven by computer science and universal access to the internet. These technologies and web connections place human observers front and center in citizen science-driven research and are critical in generating new discoveries and innovation in such fields as astronomy, biodiversity, and meteorology. Research projects utilizing a citizen science approach address scientific problems at regional, continental, and even global scales otherwise impossible for a single lab or even a small collection of academic researchers...
May 18, 2017: Insects
https://www.readbyqxmd.com/read/28523384/the-need-for-restructuring-the-disordered-science-of-amorphous-drug-formulations
#6
REVIEW
Khadijah Edueng, Denny Mahlin, Christel A S Bergström
The alarming numbers of poorly soluble discovery compounds have centered the efforts towards finding strategies to improve the solubility. One of the attractive approaches to enhance solubility is via amorphization despite the stability issue associated with it. Although the number of amorphous-based research reports has increased tremendously after year 2000, little is known on the current research practice in designing amorphous formulation and how it has changed after the concept of solid dispersion was first introduced decades ago...
May 18, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28521007/computing-the-social-brain-connectome-across-systems-and-states
#7
Daniel Alcalá-López, Jonathan Smallwood, Elizabeth Jefferies, Frank Van Overwalle, Kai Vogeley, Rogier B Mars, Bruce I Turetsky, Angela R Laird, Peter T Fox, Simon B Eickhoff, Danilo Bzdok
Social skills probably emerge from the interaction between different neural processing levels. However, social neuroscience is fragmented into highly specialized, rarely cross-referenced topics. The present study attempts a systematic reconciliation by deriving a social brain definition from neural activity meta-analyses on social-cognitive capacities. The social brain was characterized by meta-analytic connectivity modeling evaluating coactivation in task-focused brain states and physiological fluctuations evaluating correlations in task-free brain states...
May 18, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28520560/assessing-age-related-change-in-japanese-mental-foramen-opening-direction-using-multidetector-computed-tomography
#8
N Ishii, Y Makino, M Fujita, A Sakuma, S Torimitsu, F Chiba, D Yajima, G Inokuchi, A Motomura, N H Iwase, H Saitoh
OBJECTIVE: The purpose of this study was to investigate how the opening direction of the mental foramen (MF) changes with age in a Japanese population using multi-detector computed tomography (MDCT). METHODS: Post-mortem MDCT scans of 121 Japanese subjects (66 males and 55 females) were carried out where all subjects possessed at least twenty teeth, including molar teeth, in the upper and lower jaws. Two angles of the mental foramen opening were measured, namely the superior-inferior angle in the coronal plane and anterior-posterior angle in the transverse plane, on the CT reconstructed images...
December 1, 2016: Journal of Forensic Odonto-stomatology
https://www.readbyqxmd.com/read/28520421/examining-the-feasibility-of-using-free-energy-perturbation-fep-in-predicting-protein-stability
#9
Melissa Coates Ford, Kerim Babaoglu
The importance of engineering protein stability is well known and has the potential to impact many fields ranging from pharmaceuticals to food sciences. Engineering proteins can be both a time consuming and expensive experimental process. The use of computation is a potential solution to mitigating some of the time and expenses required to engineer a protein. This process has been previously hindered by inaccurate force fields or energy equations and slow computational processors, however improved software and hardware have made this goal much more attainable...
May 18, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28520235/high-dimensional-neural-network-potentials-for-complex-systems
#10
Jörg Behler
Modern simulation techniques have reached a level of maturity, which allows addressing a wide range of problems in chemistry and materials science. Unfortunately, the application of first principles methods with predictive power is still limited to rather small systems, and in spite of the rapid evolution of computer hardware no fundamental change of this situation can be expected. Consequently, to reach an atomic level understanding of complex systems, the development of more efficient but equally reliable atomistic potentials has received considerable attention in recent years...
May 18, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28512565/developments-in-the-structural-science-of-materials
#11
EDITORIAL
C Richard A Catlow
Recent developments in the structural science of materials and the growing power of computational methods in this field are discussed.
May 1, 2017: IUCrJ
https://www.readbyqxmd.com/read/28512066/use-of-electroencephalography-brain-computer-interface-systems-as-a-rehabilitative-approach-for-upper-limb-function-after-a-stroke-a-systematic-review
#12
REVIEW
Esther Monge-Pereira, Jaime Ibañez-Pereda, Isabel M Alguacil-Diego, Jose I Serrano, María P Spottorno-Rubio, Francisco Molina-Rueda
BACKGROUND: Brain computer interface (BCI) systems have been suggested as a promising tool for neurorehabilitation. However, to date, there is a lack of homogeneous findings. Furthermore, no systematic reviews have analyzed the degree of validation of these interventions for upper limb (UL) motor rehabilitation post-stroke. OBJECTIVES: To compile all available studies that assess an UL intervention based on an electroencephalography (EEG) - BCI system in stroke...
May 13, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28511513/sexual-dimorphism-of-maxillary-sinus-a-morphometric-analysis-using-cone-beam-computed-tomography
#13
Ayeesha Urooge, Bharati A Patil
INTRODUCTION: Age and sex determination in forensic sciences are primary components of any skeletal analysis. As most bones used for sex determination are recovered in incomplete state, it is often necessary to use bones that are recovered intact e.g., the maxillary sinus. Cone Beam Computed Tomography (CBCT) can provide precise information about complex anatomical structures, as it is characterized by rapid volumetric image acquisition with high resolution. AIM: The present study was designed to evaluate the size and volume of Maxillary Sinus (MS) in determining gender by CBCT...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28508809/health-information-system-in-a-cloud-computing-context
#14
Farahnaz Sadoughi, Leila Erfannia
Healthcare as a worldwide industry is experiencing a period of growth based on health information technology. The capabilities of cloud systems make it as an option to develop eHealth goals. The main objectives of the present study was to evaluate the advantages and limitations of health information systems implementation in a cloud-computing context that was conducted as a systematic review in 2016. Science direct, Scopus, Web of science, IEEE, PubMed and Google scholar were searched according study criteria...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28508359/evolving-relevance-of-neuroproteomics-in-alzheimer-s-disease
#15
Simone Lista, Henrik Zetterberg, Sid E O'Bryant, Kaj Blennow, Harald Hampel
Substantial progress in the understanding of the biology of Alzheimer's disease (AD) has been achieved over the past decades. The early detection and diagnosis of AD and other age-related neurodegenerative diseases, however, remain a challenging scientific frontier. Therefore, the comprehensive discovery (relating to all individual, converging or diverging biochemical disease mechanisms), development, validation, and qualification of standardized biological markers with diagnostic and prognostic functions with a precise performance profile regarding specificity, sensitivity, and positive and negative predictive value are warranted...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28507755/ethnic-variations-in-the-occurrence-of-colonic-neoplasms
#16
Amnon Sonnenberg, Kevin O Turner, Robert M Genta
BACKGROUND AND AIMS: With the exception of African Americans and Hispanics, few studies have dealt with the influence of other types of ethnicity on the prevalence of colon polyps and colorectal cancer. The present study was undertaken to compare the ethnic and socioeconomic distributions of colonic neoplasms among different ethnic groups in the United States. METHODS: A total of 813,057 patients, who underwent colonoscopy during 2008-2014, were recruited from an electronic database of histopathology reports (Miraca Life Sciences) for a cross-sectional study...
April 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28507695/ani-1-an-extensible-neural-network-potential-with-dft-accuracy-at-force-field-computational-cost
#17
J S Smith, O Isayev, A E Roitberg
Deep learning is revolutionizing many areas of science and technology, especially image, text, and speech recognition. In this paper, we demonstrate how a deep neural network (NN) trained on quantum mechanical (QM) DFT calculations can learn an accurate and transferable potential for organic molecules. We introduce ANAKIN-ME (Accurate NeurAl networK engINe for Molecular Energies) or ANI for short. ANI is a new method designed with the intent of developing transferable neural network potentials that utilize a highly-modified version of the Behler and Parrinello symmetry functions to build single-atom atomic environment vectors (AEV) as a molecular representation...
April 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28507240/mathematical-methods-in-medicine-neuroscience-cardiology-and-pathology
#18
José M Amigó, Michael Small
The application of mathematics, natural sciences and engineering to medicine is gaining momentum as the mutual benefits of this collaboration become increasingly obvious. This theme issue is intended to highlight the trend in the case of mathematics. Specifically, the scope of this theme issue is to give a general view of the current research in the application of mathematical methods to medicine, as well as to show how mathematics can help in such important aspects as understanding, prediction, treatment and data processing...
June 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28507228/understanding-principles-of-integration-and-segregation-using-whole-brain-computational-connectomics-implications-for-neuropsychiatric-disorders
#19
REVIEW
Louis-David Lord, Angus B Stevner, Gustavo Deco, Morten L Kringelbach
To survive in an ever-changing environment, the brain must seamlessly integrate a rich stream of incoming information into coherent internal representations that can then be used to efficiently plan for action. The brain must, however, balance its ability to integrate information from various sources with a complementary capacity to segregate information into modules which perform specialized computations in local circuits. Importantly, evidence suggests that imbalances in the brain's ability to bind together and/or segregate information over both space and time is a common feature of several neuropsychiatric disorders...
June 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28507154/information-socialtaxis-and-efficient-collective-behavior-emerging-in-groups-of-information-seeking-agents
#20
Ehud D Karpas, Adi Shklarsh, Elad Schneidman
Individual behavior, in biology, economics, and computer science, is often described in terms of balancing exploration and exploitation. Foraging has been a canonical setting for studying reward seeking and information gathering, from bacteria to humans, mostly focusing on individual behavior. Inspired by the gradient-climbing nature of chemotaxis, the infotaxis algorithm showed that locally maximizing the expected information gain leads to efficient and ethological individual foraging. In nature, as well as in theoretical settings, conspecifics can be a valuable source of information about the environment...
May 15, 2017: Proceedings of the National Academy of Sciences of the United States of America
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