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https://www.readbyqxmd.com/read/29792340/multidisciplinary-care-model-for-hiv-improves-treatment-outcome-a-single-centre-experience-from-the-middle-east
#1
Ali Elgalib, Halima Al-Sawafi, Bina Kamble, Saud Al-Harthy, Qamra Al-Sariri
Multidisciplinary team (MDT) care models have been shown to improve clinical outcomes among HIV patients. We aim to assess the impact of adopting MDT approach in a tertiary HIV clinic in Muscat, Sultanate of Oman. We introduced MDT approach in our HIV centre in January 2016 where existing team members (counsellors, nurses, social workers, pharmacists and doctors) worked together, through care pathways, to support patients as they go through the HIV care continuum from diagnosis to viral suppression. Notes were reviewed for demographics and clinical data...
May 24, 2018: AIDS Care
https://www.readbyqxmd.com/read/29792255/effectiveness-of-adolescent-peer-education-programs-on-reducing-hiv-sti-risk-an-integrated-review
#2
Ganga Mahat, Mary Ann Scoloveno
There is empirical evidence suggesting that peer education is efficacious in changing adolescent sexual risk behaviors; however, it is unclear if there are similarities in outcomes across studies. Thus, the purpose of this review was to synthesize published research on peer-led HIV/STI intervention programs for adolescents in an effort to determine the efficacy of peer education on knowledge, attitudes, normative beliefs, and sexual behavior. Data collection included online searches of published research from Index Medicus (Medline), Cumulative Index to Nursing and Allied Health Literature (CINAHL), Educational Resources Information Center (ERIC), Educational Index, and PsycINFO (including PsycARTICLES) from 2000 to 2016...
May 1, 2018: Research and Theory for Nursing Practice
https://www.readbyqxmd.com/read/29791642/integrative-review-of-literature-nursing-care-to-aged-people-with-hiv
#3
Arayana Gomes da Silva, Viviane Siqueira Cavalcanti, Tâmyssa Simões Dos Santos, Gabriela Rodrigues Bragagnollo, Karen da Silva Santos, Ivanilde Miciele da Silva Santos, Kristiana Cerqueira Mousinho, Cinira Magali Fortuna
OBJECTIVE: To identify evidences in scientific Brazilian literature on nursing care to aged people with HIV. METHOD: Integrative review of literature from databases: Latin American and Caribbean Literature on Health Sciences (LILACS), Scientific Eletronic Library Online (SciELO), Cochrane and the Nursing Database (BDENF). The applied inclusion criteria were publications that were fully available from 2001 to 2015 and answered to the guiding question of this study...
2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29791547/predictors-of-mortality-among-intensive-care-unit-patients-coinfected-with-tuberculosis-and-hiv
#4
Marcia Danielle Ferreira, Cynthia Pessoa das Neves, Alexandra Brito de Souza, Francisco Beraldi-Magalhães, Giovanni Battista Migliori, Afrânio Lineu Kritski, Marcelo Cordeiro-Santos
OBJECTIVE: To identify factors predictive of mortality in patients admitted to the ICU with tuberculosis (TB)/HIV coinfection in the Manaus, Amazon Region. METHODS: This was a retrospective cohort study of TB/HIV coinfected patients over 18 years of age who were admitted to an ICU in the city of Manaus, Brazil, between January of 2011 and December of 2014. Sociodemographic, clinical, and laboratory variables were assessed. To identify factors predictive of mortality, we employed a Cox proportional hazards model...
April 2018: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/29791514/high-prevalence-of-syndemic-health-problems-in-patients-seeking-post-exposure-prophylaxis-for-sexual-exposures-to-hiv
#5
Steven A Morrison, Deborah Yoong, Trevor A Hart, Paul MacPherson, Isaac Bogoch, Vishalini Sivarajah, Kevin Gough, Mark Naccarato, Darrell H S Tan
INTRODUCTION: The standard clinical approach to non-occupational HIV post-exposure prophylaxis (nPEP) focuses on biomedical aspects of the intervention, but may overlook co-occurring or 'syndemic' psychosocial problems that reinforce future vulnerability to HIV. We therefore sought to determine the prevalence of syndemic health problems in a cohort of Ontario nPEP patients, and explored the relationship between syndemic burden and HIV risk. METHODS: Between 07/2013-08/2016, we distributed a self-administered questionnaire to patients presenting to three clinics in Toronto and Ottawa seeking nPEP for sexual HIV exposures...
2018: PloS One
https://www.readbyqxmd.com/read/29790923/missed-opportunities-to-prescribe-preexposure-prophylaxis-in-south-carolina-2013-2016
#6
Dawn K Smith, Man-Huei Chang, Wayne A Duffus, Stella Okoye, Sharon Weissman
Introduction: Expanding use of preexposure prophylaxis (PrEP) in ways that address current racial/ethnic disparities is an important HIV prevention goal. We investigated missed opportunities to provide PrEP during healthcare visits occurring prior to HIV infection. Methods: This retrospective cohort study linked South Carolina HIV case surveillance data to 3 statewide healthcare databases. Characteristics of patients, health care visits and providers, sexually transmitted diseases (STD), and other diagnoses, were assessed for medical encounters occurring before an initial HIV diagnosis...
May 22, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29790827/the-effect-of-maternal-hiv-status-and-treatment-duration-on-body-composition-of-hiv-exposed-and-hiv-unexposed-preterm-very-and-extremely-low-birthweight-infants
#7
Klara Strydom, Daniel Gerhardus Nel, Muhammad Ali Dhansay, Evette Van Niekerk
BACKGROUND: There is an evidence gap regarding the relationship between HIV exposure, body composition (and the quality thereof) and preterm infants. AIM: This study determined the body composition of HIV-exposed, preterm very low-birthweight (VLBW) and extremely low-birthweight (ELBW) infants and to assess the effect of maternal HAART duration on the body composition of this vulnerable population. METHODS: A descriptive cross-sectional study was conducted...
May 23, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/29790407/age-cohort-and-health-service-utilization-among-gay-men
#8
Daniel C Green, Jeremy T Goldbach, Henry F Raymond
Gay men report unique health disparities and service utilization trends compared to their heterosexual peers including a lack of health-care participation which may lead to chronic health conditions. Limited research has been conducted analyzing group differences among gay men such as the influence of one's age cohort on disparities. The aim of this study was to examine the association age cohort has on health service utilization among gay men. A sample of 383 self-identified gay men was collected by the San Francisco Department of Public Health...
May 1, 2018: American Journal of Men's Health
https://www.readbyqxmd.com/read/29790075/pathways-from-resilient-coping-to-safer-sex-communication-among-african-caribbean-and-black-women-in-toronto-canada-results-from-a-cross-sectional-survey
#9
Carmen H Logie, Moses Okumu, Shannon Ryan, Mary Yehdego
PURPOSE: African, Caribbean, and Black (ACB) women in Canada are disproportionately impacted by HIV and other sexually transmitted infections. Although there is reported suboptimal consistent condom use with ACB women, limited research has explored safer sex communication among this population. Coping frameworks highlight the role that resilient coping and condom use self-efficacy may play in facilitating safer sex communication. Structural perspectives stress the need to explore associations between HIV vulnerabilities and food insecurity...
May 22, 2018: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29789804/health-risk-behaviour-among-adolescents-living-with-hiv-in-sub-saharan-africa-a-systematic-review-and-meta-analysis
#10
REVIEW
Derrick Ssewanyana, Patrick N Mwangala, Anneloes van Baar, Charles R Newton, Amina Abubakar
The burden of health risk behaviour (HRB) among adolescents living with HIV (ALWHIV) in sub-Saharan Africa (SSA) is currently unknown. A systematic search for publications on HRB among ALWHIV in SSA was conducted in PubMed, Embase, PsycINFO, and Applied Social Sciences Index and Abstracts databases. Results were summarized following PRISMA guidelines for systematic reviews and meta-analyses. Heterogeneity was assessed by the DerSimonian and Laird method and the pooled estimates were computed. Prevalence of current condom nonuse behaviour was at 59...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29788934/the-lung-microbiome-in-children-with-hiv-bronchiectasis-a-cross-sectional-pilot-study
#11
Refiloe Masekela, Solize Vosloo, Stephanus N Venter, Wilhelm Z de Beer, Robin J Green
BACKGROUND: Data on the lung microbiome in HIV-infected children is limited. The current study sought to determine the lung microbiome in HIV-associated bronchiectasis and to assess its association with pulmonary exacerbations. METHODS: A cross-sectional pilot study of 22 children (68% male; mean age 10.8 years) with HIV-associated bronchiectasis and a control group of 5 children with cystic fibrosis (CF). Thirty-one samples were collected, with 11 during exacerbations...
May 22, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29788421/predicting-viral-failure-in-human-immunodeficiency-virus-perinatally-infected-youth-with-persistent-low-level-viremia-on-highly-active-antiretroviral-therapy
#12
Ruth Pereira, David A Ludwig, Sunil Mathew, Claudia Flores, Sady Dominguez, Ivan Gonzalez, Delia Rivera-Hernandez, Gwendolyn B Scott, Charles D Mitchell
Background: Less than optimal adherence with antiretroviral therapy occurs commonly among human immunodeficiency virus HIV)-infected youth. In this study, our object was to identify patterns in the prefailure measurement of viral load (VL) that can reliably predict virological failure (VF) in HIV perinatally infected youth on highly active antiretroviral therapy (HAART). Methods: We conducted a retrospective chart review of HIV-infected youth with low-level viremia (LLV), defined as an HIV VL between the lower limits of detection (20-75 copies/mL) and 1000 copies/mL...
May 19, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29788066/lipid-changes-and-tolerability-in-a-cohort-of-adult-hiv-infected-patients-who-switched-to-rilpivirine-emtricitabine-tenofovir-due-to-intolerance-to-previous-combination-art-the-pro-str-study
#13
A Ocampo, P Domingo, P Fernández, J Diz, J R Barberá, M A Sepúlveda, X Salgado, M Rodriguez, J Santos, M Yzusqui, M I Mayorga, J F Lorenzo, A Bahamonde, P Bachiller, E Martínez, N Rozas, C Torres, A Muñoz, A Casado, D Podzamczer
Objectives: To analyse lipid changes and tolerability in a cohort of HIV-infected patients who switched their antiretroviral regimens to rilpivirine/emtricitabine/tenofovir (RPV/FTC/TDF) in a real-world setting. Methods: PRO-STR is a 48 week prospective observational post-authorization study in 25 hospitals. Patients with a viral load <1000 copies/mL, receiving at least 12 months of combination ART (cART), with constant posology for at least the prior 3 months, were categorized according to previous treatment [NNRTI or ritonavir-boosted PI (PI/r)]...
May 16, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29788039/frailty-neurocognitive-impairment-or-both-in-predicting-poor-health-outcomes-among-adults-living-with-hiv
#14
Kristine M Erlandson, Jeremiah Perez, Mona Abdo, Kevin Robertson, Ronald J Ellis, Susan L Koletar, Robert Kalayjian, Babafemi Taiwo, Frank J Palella, Katherine Tassiopoulos
Background: Neurocognitive impairment (NCI) is strongly associated with frailty in people living with HIV (PLWH); the overlap of frailty and NCI, and the impact on health outcomes in PLWH is unknown. Methods: PLWH in a longitudinal, observational study of aging completed entry evaluations for frailty and NCI. Outcomes were falls (recurrent), increased limitations in independent activities of daily living, or mortality and were combined. Poisson regression models estimated prevalence ratios (PR) for ≥1 outcome over 2 years...
May 18, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29787596/survival-and-predictors-of-mortality-among-children-co-infected-with-tuberculosis-and-human-immunodeficiency-virus-at-university-of-gondar-comprehensive-specialized-hospital-northwest-ethiopia-a-retrospective-follow-up-study
#15
Kendalem Asmare Atalell, Nigusie Birhan Tebeje, Daniale Tekelia Ekubagewargies
BACKGROUND: Tuberculosis (TB) is the leading cause of death in Human immunodeficiency virus (HIV) infected children globally. The aims of this study were to determine the mortality rate and to identify the predictors of mortality among TB/HIV co-infected children at University of Gondar Comprehensive Specialized Hospital. METHOD: A retrospective follow-up study was conducted among TB/HIV co-infected children from February 2005 to March 2017. A Kaplan-Meier curve was used to estimate the median survival time...
2018: PloS One
https://www.readbyqxmd.com/read/29787580/risk-behaviors-and-hiv-care-continuum-outcomes-among-criminal-justice-involved-hiv-infected-transgender-women-and-cisgender-men-data-from-the-seek-test-treat-and-retain-harmonization-initiative
#16
Curt G Beckwith, Irene Kuo, Rob J Fredericksen, Lauren Brinkley-Rubinstein, William E Cunningham, Sandra A Springer, Kelsey B Loeliger, Julie Franks, Katerina Christopoulos, Jennifer Lorvick, Shoshana Y Kahana, Rebekah Young, David W Seal, Chad Zawitz, Joseph A Delaney, Heidi M Crane, Mary L Biggs
BACKGROUND: Transgender persons are highly victimized, marginalized, disproportionately experience incarceration, and have alarmingly increased rates of HIV infection compared to cis-gender persons. Few studies have examined the HIV care continuum outcomes among transgender women (TW), particularly TW who are involved with the criminal justice (CJ) system. METHODS: To improve our understanding of HIV care continuum outcomes and risk behaviors among HIV-infected TW who are involved with the CJ system, we analyzed data from the National Institute on Drug Abuse-supported Seek, Test, Treat, Retain (STTR) Data Harmonization Initiative...
2018: PloS One
https://www.readbyqxmd.com/read/29786136/temporal-trends-in-the-epidemiology-of-cervical-cancer-in-south-africa-1994-2012
#17
Gbenga Olorunfemi, Ntombizodwa Ndlovu, Gwinyai Masukume, Admire Chikandiwa, Pedro T Pisa, Elvira Singh
Cervical cancer (CC) is the leading cause of cancer death among female South Africans (SA). Improved access to reproductive health services following multi-ethnic democracy in 1994, HIV epidemic, and the initiation of CC population-based screening in early 2000's have influenced the epidemiology of CC in SA. We therefore evaluated the trends in CC age-standardized incidence (ASIR) (1994 - 2009) and mortality rates (ASMR) (2004 - 2012) using data from the South African National Cancer Registry and the Statistics South Africa, respectively...
May 22, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29784846/pharmacokinetics-of-piperaquine-and-safety-profile-of-dihydroartemisinin-piperaquine-co-administered-with-antiretroviral-therapy-in-malaria-uninfected-hiv-positive-malawian-adults
#18
Clifford G Banda, Fraction Dzinjalamala, Mavuto Mukaka, Jane Mallewa, Victor Maiden, Dianne J Terlouw, David G Lalloo, Saye H Khoo, Victor Mwapasa
There are limited data on the pharmacokinetic and safety profiles of dihydroartemisinin-piperaquine (DHA-PQ) among human immunodeficiency virus infected (HIV+) individuals taking antiretroviral therapy (ART). In a two step (parallel-group) pharmacokinetic trial with intensive blood sampling, we compared area under the concentration-time curve (AUC0-28 days ) and safety outcomes of piperaquine among malaria-uninfected HIV+ adults. In step 1, half the adult dose of DHA-PQ was administered for three days as an intitial safety check in four groups (n=6/group) of HIV+ adults (age≥18 years): (i) antiretroviral-naïve, (ii) on nevirapine-based ART, (iii) on efavirenz-based ART, and (iv) on ritonavir-boosted lopinavir-based ART...
May 21, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29784840/oxidative-stress-and-first-line-antituberculosis-drug-induced-hepatotoxicity
#19
Wing Wai Yew, Kwok Chiu Chang, Denise P Chan
Hepatotoxicity induced by antituberculosis drugs is a serious adverse reaction with significant morbidity and even rarely mortality. This form of toxicity potentially impacts the treatment outcome of tuberculosis in some patients. Confining to first-line antituberculosis drugs, this review addresses whether and how oxidative stress, and more broadly, disturbance in redox homeostasis alongside mitochondrial dysfunction, may contribute to the hepatotoxicity induced by them. Risk factors for such toxicity that have been identified, in addition to genetic factors, principally include old age, malnutrition, alcoholism, chronic hepatitis C and chronic hepatitis B infection, HIV infection and pre-existing liver disease...
May 21, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29784114/hookup-app-use-sexual-behavior-and-sexual-health-among-adolescent-men-who-have-sex-with-men-in-the-united-states
#20
Kathryn Macapagal, David A Moskowitz, Dennis H Li, Andrés Carrión, Emily Bettin, Celia B Fisher, Brian Mustanski
PURPOSE: Geosocial networking applications (e.g., "hookup apps") are widely used among adult men who have sex with men (MSM). Little is known about adolescent MSM's (AMSM) use of these apps. Exploratory research is needed as AMSM's app use poses various ethical, legal, and sexual health concerns. This article examined AMSM's app use patterns and its associations with their sexual health and behavior. METHODS: Two hundred sexually experienced AMSM in the United States (M age = 16...
June 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
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