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https://www.readbyqxmd.com/read/27933425/ethical-issues-in-using-social-media-to-deliver-an-hiv-prevention-intervention-results-from-the-hope-peru-study
#1
Renee Garett, Luis Menacho, Sean D Young
Social media technologies have become increasingly useful tools for research-based interventions. However, participants and social media users have expressed ethical concerns with these studies, such as risks and benefits of participation, as well as privacy, confidentiality, and informed consent issues. This study was designed to follow up with and assess experiences and perceptions of ethics-related issues among a sample of 211 men who have sex with men who participated in the Harnessing Online Peer Education (HOPE) Peru study, a randomized controlled HIV prevention intervention conducted in Peru...
December 9, 2016: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/27932521/adapting-an-hiv-risk-reduction-curriculum-processes-and-outcomes
#2
Melissa K Miller, Joi Wickliffe, Sharon G Humiston, M Denise Dowd, Patricia Kelly, Stephen DeLurgio, Kathy Goggin
Becoming a Responsible Teen (BART) is a community-based, HIV risk reduction curriculum shown to increase safer sex behaviors among African American adolescents. However, BART does not address common barriers to sexual health care access, which may limit program efficacy. We used a community-engaged adaptation process to maximize program relevance and health outcomes by incorporating a broad ecological perspective. Adolescent and staff advisory boards at a community-based organization recommended modifications (e...
December 7, 2016: Health Promotion Practice
https://www.readbyqxmd.com/read/27932339/predictors-of-treatment-failure-on-second-line-antiretroviral-therapy-among-adults-in-northwest-ethiopia-a-multicentre-retrospective-follow-up-study
#3
Adino Tesfahun Tsegaye, Mamo Wubshet, Tadesse Awoke, Kefyalew Addis Alene
BACKGROUND: The number of patients using second-line antiretroviral therapy (ART) has increased over time. In Ethiopia, 1.5% of HIV infected patients on ART are using a second-line regimen and little is known about its effect in this setting. OBJECTIVE: To estimate the rate and predictors of treatment failure on second-line ART among adults living with HIV in northwest Ethiopia. SETTING: An institution-based retrospective follow-up study was conducted at three tertiary hospitals in northwest Ethiopia from March to May 2015...
December 8, 2016: BMJ Open
https://www.readbyqxmd.com/read/27932200/the-seroprevalence-of-hepatitis-b-hepatitis-c-and-human-immunodeficiency-virus-in-patients-undergoing-septoplasty
#4
Ozlem Onerci Celebi, Ela Araz Server, Bahtiyar Hamit, Özgür Yiğit
INTRODUCTION: Worldwide, hepatitis B virus, hepatitis C virus, and human immunodeficiency virus are major health problems. Healthcare workers are at risk of transmitting blood-borne viruses, and surgeons have a higher risk of exposure to blood and higher rates of percutaneous injury than other healthcare workers. Septoplasty is among the 3 most commonly performed otolaryngological surgeries worldwide. OBJECTIVE: To determine the seroprevalence of Hepatitis B surface antigen, Hepatitis C virus antibody, and Human Immunodeficiency Virus antibody in patients undergoing septoplasty with and without turbinate surgery under general anesthesia, and to determine if preoperative testing should be performed in such patients...
November 17, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/27932056/sexual-orientation-disparities-in-the-utilization-of-sexual-health-services-in-a-national-probability-sample-of-u-s-women
#5
Madina Agénor, Christina A Muzny, Vanessa Schick, Erika L Austin, Jennifer Potter
Although sexual minority women are at risk of sexually transmitted infections (STIs) and cervical cancer, few nationally representative studies have assessed sexual orientation disparities in sexual health care among women. Using data from the 2011-2013 and 2013-2015 waves of the National Survey of Family Growth, which provide a national probability sample of U.S. women aged 15-44years (N=11.300), we used multivariable logistic regression to examine the associations between sexual behavior and sexual identity (modeled separately) and STI testing in the past year, Pap test use in the last 3years, lifetime HIV testing, and lifetime human papillomavirus (HPV) testing...
December 5, 2016: Preventive Medicine
https://www.readbyqxmd.com/read/27931753/medication-adherence-in-13-to-24-year-old-youth-living-with-hiv
#6
Tiffany Chenneville, Marielle Machacek, Audra St John Walsh, Patricia Emmanuel, Carina Rodriguez
Despite advances in HIV medicine, adherence presents as a barrier to effective treatment for youth. We designed this study to assess medication knowledge, adherence, and factors affecting adherence in youth with HIV. Participants were 72 youth ages 13 to 24 years with perinatally or behaviorally acquired HIV. Demographic data were collected and a self-report adherence interview was administered. Interviews were audio-recorded to allow for qualitative data analysis. Self-reported adherence varied depending on the framing of questions, with participants reporting greater adherence when asked how many doses they had missed within the past 7 days compared to results from a 7-day recall interview...
November 11, 2016: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/27931519/high-prevalence-of-hiv-chlamydia-and-gonorrhoea-among-men-who-have-sex-with-men-and-transgender-women-attending-trusted-community-centres-in-abuja-and-lagos-nigeria
#7
Babajide Keshinro, Trevor A Crowell, Rebecca G Nowak, Sylvia Adebajo, Sheila Peel, Charlotte A Gaydos, Cristina Rodriguez-Hart, Stefan D Baral, Melissa J Walsh, Ogbonnaya S Njoku, Sunday Odeyemi, Teclaire Ngo-Ndomb, William A Blattner, Merlin L Robb, Manhattan E Charurat, Julie Ake
INTRODUCTION: Sexually transmitted infection (STI) and HIV prevalence have been reported to be higher amongst men who have sex with men (MSM) in Nigeria than in the general population. The objective of this study was to characterize the prevalence of HIV, chlamydia and gonorrhoea in this population using laboratory-based universal testing. METHODS: TRUST/RV368 represents a cohort of MSM and transgender women (TGW) recruited at trusted community centres in Abuja and Lagos, Nigeria, using respondent-driven sampling (RDS)...
2016: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/27931335/clinical-characteristics-and-outcomes-of-tuberculosis-in-douala-cameroon-a-7-year-retrospective-cohort-study
#8
B H Mbatchou Ngahane, F Dahirou, C Tchieche, A Wandji, C Ngni, A Nana-Metchedjin, E Nyankiy, M L Endale Mangamba, C Kuaban
SETTING: Tuberculosis (TB) clinic, Douala Laquintinie Hospital, Douala, Cameroon. OBJECTIVE: To describe the clinical characteristics of TB and to investigate predictors of poor treatment outcomes. DESIGN: A registry-based, retrospective cohort study of all TB cases recorded from 2007 to 2013 was conducted. Multinomial logistic regression models were used to identify predictors of poor outcomes. RESULTS: Of 8902 TB cases included, 5110 (57...
December 2016: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/27931232/retention-in-georgia-opioid-substitution-therapy-program-and-associated-factors
#9
Ekaterine Ruadze, Khatuna Todadze
BACKGROUND: Substance abuse has been considered as a growing challenge in Georgia that is closely linked with human immune deficiency virus (HIV) and hepatitis C transmission due to unsafe injection and other uncontrolled behaviors. Methadone maintenance therapy is one of the major treatment options for opioid-dependent individuals. It has proven efficacy in decreasing illegal opioid consumption and criminal behavior as well as reducing the level of HIV infection, mortality, HCV infection, and increasing social functioning...
December 8, 2016: Harm Reduction Journal
https://www.readbyqxmd.com/read/27930720/early-resumption-of-sex-following-voluntary-medical-male-circumcision-amongst-school-going-males
#10
Gavin George, Kaymarlin Govender, Sean Beckett, Carl Montague, Janet Frohlich
Voluntary medical male circumcision is an integral part of the South African government's response to the HIV and AIDS epidemic. Following circumcision, it is recommended that patients abstain from sexual activity for six weeks, as sex may increase the risk of female-to-male HIV transmission and prolong the healing period. This paper investigates the resumption of sexual activity during the healing period among a cohort of school-going males in the KwaZulu-Natal province of South Africa. The analysis for this paper compares two groups of sexually active school-going males: the first group reported having sex during the healing period (n = 40) and the second group (n = 98) reported no sex during the healing period (mean age: 17...
2016: PloS One
https://www.readbyqxmd.com/read/27930613/project-shikamana-baseline-findings-from-a-community-empowerment-based-combination-hiv-prevention-trial-among-female-sex-workers-in-iringa-tanzania
#11
Deanna Kerrigan, Jessie Mbwambo, Samuel Likindikoki, Sarah Beckham, Ard Mwampashi, Catherine Shembilu, Andrea Mantsios, Anna Leddy, Wendy Davis, Noya Galai
BACKGROUND: Community empowerment approaches have been found to be effective in responding to HIV among female sex workers (FSWs) in South Asia and Latin America. To date, limited rigorous evaluations of these approaches have been conducted in sub-Saharan Africa. METHODS: A phase II community randomized controlled trial is being conducted in Iringa, Tanzania, to evaluate the effectiveness of a community empowerment-based combination HIV prevention model (Project Shikamana) among a stratified sample of HIV-infected and HIV-uninfected FSWs...
January 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27930599/the-hiv-care-cascade-among-female-sex-workers-in-zimbabwe-results-of-a-population-based-survey-from-the-sisters-antiretroviral-therapy-programme-for-prevention-of-hiv-an-integrated-response-sapph-ire-trial
#12
Frances M Cowan, Calum Davey, Elizabeth Fearon, Phillis Mushati, Jeffrey Dirawo, Valentina Cambiano, Sue Napierala Mavedzenge, Dagmar Hanisch, Ramona Wong-Gruenwald, Milton Chemhuru, Nyasha Masuka, Karin Hatzold, Owen Mugurungi, Joanna Busza, Andrew Phillips, James R Hargreaves
INTRODUCTION: Female sex workers (FSW) in sub-Saharan Africa have a higher prevalence of HIV than other women of reproductive age. Social, legal, and structural barriers influence their access to care. Little is known about the HIV diagnosis and care cascade in most countries in southern Africa. We aimed to describe the HIV diagnosis and care cascade among FSW in Zimbabwe. METHODS: We conducted cross-sectional respondent driven sampling (RDS) surveys of FSW in 14 sites across Zimbabwe as the baseline for a cluster-randomised controlled trial investigating a combination HIV prevention and care package...
December 1, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27930403/has-the-phasing-out-of-stavudine-in-accordance-with-changes-in-who-guidelines-led-to-a-decrease-in-single-drug-substitutions-in-first-line-antiretroviral-therapy-for-hiv-in-sub-saharan-africa
#13
Alana T Brennan, Mary-Ann Davies, Jacob Bor, Gilles Wandeler, Kathryn Stinson, Robin Wood, Hans Prozesky, Frank Tanser, Geoffrey Fatti, Andrew Boulle, Izukanji Sikazwe, Kara Wools-Kaloustian, Constantin Yiannoutsos, Valériane Leroy, Nathalie de Rekeneire, Matthew P Fox
OBJECTIVE: We assessed the relationship between phasing out stavudine in first-line antiretroviral therapy (ART) in accordance with WHO 2010 policy and single-drug substitutions (SDS) (substituting the nucleoside reverse transcriptase inhibitor in first-line ART) in sub-Saharan Africa. DESIGN: Prospective cohort analysis (International epidemiological Databases to Evaluate AIDS-Multiregional) including ART-naive, HIV-infected patients aged at least 16 years, initiating ART between January 2005 and December 2012...
January 2, 2017: AIDS
https://www.readbyqxmd.com/read/27929355/global-physical-activity-levels-among-people-living-with-hiv-a-systematic-review-and-meta-analysis
#14
Davy Vancampfort, James Mugisha, Marc De Hert, Michel Probst, Joseph Firth, Paul Gorczynski, Brendon Stubbs
PURPOSE: It is unclear how much physical activity people living with HIV (PLWH) engage in. We conducted a meta-analysis to investigate physical activity levels and its predictors in PLWH. METHODS: PubMed, PsycARTICLES, and CINAHL Plus were searched by two independent reviewers from inception till 1 April 2016 using the keywords: "HIV" OR "AIDS" AND "physical activity" OR "exercise" OR "sports". A random effects meta-analysis was conducted. RESULTS: Across 24 studies including 34 physical activity levels there were 3780 (2471♂) PLWH (mean age range: 37-58 years)...
December 8, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27929270/sexually-transmitted-infections-recommendations-from-the-u-s-preventive-services-task-force
#15
Karen C Lee, Quyen Ngo-Metzger, Tracy Wolff, Joya Chowdhury, Michael L LeFevre, David S Meyers
The U.S. Preventive Services Task Force (USPSTF) has issued recommendations on behavioral counseling to prevent sexually transmitted infections (STIs) and recommendations about screening for individual STIs. Clinicians should obtain a sexual history to assess for behaviors that increase a patient's risk. Community and population risk factors should also be considered. The USPSTF recommends intensive behavioral counseling for all sexually active adolescents and for adults whose history indicates an increased risk of STIs...
December 1, 2016: American Family Physician
https://www.readbyqxmd.com/read/27928640/diabetes-as-a-risk-factor-in-patients-undergoing-groin-hernia-surgery
#16
Gustaf Hellspong, Ulf Gunnarsson, Ursula Dahlstrand, Gabriel Sandblom
BACKGROUND: Diabetes is a known risk factor for early postoperative complications. Even so, the incidence of acute postoperative complications following routine hernia surgery is seldom described, and the risk for reoperation for recurrence has hardly been studied. Our aim was to explore if diabetes is a significant risk factor for complications after inguinal hernia surgery. METHODS: All inguinal hernia repairs registered in the Swedish Hernia Register between 2002 and 2011 were identified...
December 7, 2016: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/27927871/severity-of-respiratory-syncytial-virus-lower-respiratory-tract-infection-with-viral-coinfection-in-hiv-uninfected-children
#17
Natalie I Mazur, Louis Bont, Adam L Cohen, Cheryl Cohen, Anne von Gottberg, Michelle J Groome, Orienka Hellferscee, Kerstin Klipstein-Grobusch, Omphile Tschegofatso Mekgoe, Fathima Naby, Jocelyn Moyes, Stefano Tempia, Florette K Treurnicht, Marietje Venter, Sibongile Walaza, Nicole Wolter, Shabir A Madhi
BACKGROUND: Molecular diagnostics enable sensitive detection of respiratory viruses but their clinical significance remains unclear in pediatric lower respiratory tract infections (LRTI). We aimed to determine whether viral coinfections increased life-threatening disease in a large cohort. METHODS: Molecular testing was performed for respiratory viruses in nasopharyngeal aspirates collected from children aged <5 years within 24 hours of hospital admission during sentinel surveillance for Severe Acute Respiratory Illness (SARI) hospitalisation conducted in South Africa during February 2009-December 2013...
December 7, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27927859/systemic-elevation-of-proinflammatory-interleukin-18-in-hiv-hcv-coinfection-versus-hiv-or-hcv-monoinfection
#18
Rebecca T Veenhuis, Jacquie Astemborski, Michael A Chattergoon, Paige Greenwood, Marissa Jarosinski, Richard D Moore, Shruti H Mehta, Andrea L Cox
BACKGROUND: HIV/HCV coinfection and elevated interleukin (IL)-18 levels are both associated with enhanced progression of hepatic inflammation and increased risk of diabetes, kidney disease, and cardiovascular disease. IL-18 is a proinflammatory cytokine made upon activation of the inflammasome, an innate sensing system. We assessed whether increased IL-18 could explain the increased incidence and progression of inflammatory conditions seen with HIV/HCV coinfection. METHODS: Serum from 559 subjects with HIV monoinfection, HCV monoinfection, HIV/HCV coinfection, or people who inject drugs with neither infection was tested for IL-18 by ELISA and for 16 other analytes by electrochemiluminescence immunoassay...
December 7, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27927856/the-long-term-mortality-of-tuberculosis-meningitis-patients-in-new-york-city-a-cohort-study
#19
Christopher Vinnard, Liza King, Sonal Munsiff, Aldo Crossa, Kentaro Iwata, Jotam Pasipanodya, Douglas Proops, Shama Ahuja
BACKGROUND: Tuberculosis meningitis (TBM) is the most devastating clinical presentation of infection with M. tuberculosis; delayed initiation of effective anti-tuberculosis (TB) therapy is associated with poor treatment outcomes. Our objective was to determine the relationship between drug resistance and 10-year mortality among TBM patients. METHODS: We conducted a retrospective cohort study of 324 patients with culture-confirmed TBM, susceptibility results reported for isoniazid and rifampin, and initiation of at least two anti-TB drugs, reported to the TB registry in New York City, NY (US) between January 1, 1992 and December 31, 2001...
December 7, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27927852/frequency-of-viremic-episodes-in-hiv-infected-women-initiating-antiretroviral-therapy-during-pregnancy-a-cohort-study
#20
Landon Myer, Lorna Dunning, Maia Lesosky, Nei-Yuan Hsiao, Tamsin Phillips, Greg Petro, Allison Zerbe, James A McIntyre, Elaine J Abrams
BACKGROUND: The numbers of HIV-infected women initiating antiretroviral therapy (ART) in pregnancy are increasing rapidly with global policy changes. There are widespread concerns about ART adherence during pregnancy and postpartum but few data on viral suppression (VS) over time in these populations. METHODS: We followed a cohort of 523 women in Cape Town, South Africa initiating ART in pregnancy (once daily tenofovir 300mg, emtracitabine 200mg and efavirenz 600mg) and achieving VS (<50 copies/mL)...
December 7, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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