keyword
MENU ▼
Read by QxMD icon Read
search

Clinical problem-solving

keyword
https://www.readbyqxmd.com/read/28806606/imbalance-between-abstract-and-concrete-repetitive-thinking-modes-in-schizophrenia
#1
Pierre Maurage, Pierre Philippot, Delphine Grynberg, Dominique Leleux, Benoît Delatte, Camille Mangelinckx, Jan-Baptist Belge, Eric Constant
OBJECTIVE: Repetitive thoughts can be divided in two modes: abstract/analytic (decontextualized and dysfunctional) and concrete/experiential (problem-focused and adaptive). They constitute a transdiagnostic process involved in many psychopathological states but have received little attention in schizophrenia, as earlier studies only indexed increased ruminations (related to dysfunctional repetitive thoughts) without jointly exploring both modes. This study explored the two repetitive thinking modes, beyond ruminations, to determine their imbalance in schizophrenia...
July 1, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28806582/beck-s-cognitive-theory-and-the-response-style-theory-of-depression-in-adolescents-with-and-without-mild-to-borderline-intellectual-disability
#2
Martine M Weeland, Karin S Nijhof, R Otten, Ignace P R Vermaes, Jan K Buitelaar
AIM: This study tests the validity of Beck's cognitive theory and Nolen-Hoeksema's response style theory of depression in adolescents with and without MBID. METHODS: The relationship between negative cognitive errors (Beck), response styles (Nolen-Hoeksema) and depressive symptoms was examined in 135 adolescents using linear regression. RESULTS: The cognitive error 'underestimation of the ability to cope' was more prevalent among adolescents with MBID than among adolescents with average intelligence...
August 11, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28805770/-new-classifications-of-epilepsies-and-seizure-types-created-by-the-international-league-against-epilepsy-2017
#3
Ye V Makushkin, S N Oskolkova, G A Fastovtsov
First part of this review (Chapter 1) demonstrates an ambiguous attitude toward psychiatry among professionals and in society in recent decades. The articles of supporters and opponents of psychiatry are also quoted. The authors describe the dynamics of the reflection of psychopathology in the main widely accepted classifications and manuals. Critical and negative opinions regarding the DSM-5, due to its role in the 'medicalization' processes, for the movement 'World Mental Health', are mentioned. The history of antipsychiatry movement and its results for psychiatry and society are analyzed as well...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28805768/-organization-of-out-patient-psychiatric-care-in-dementia-and-cognitive-impairment-in-aged-part-ii-clinical-and-economic-efficacy-of-memory-clinics-and-alzheimer-s-disease-centers
#4
N M Mikhaylova
The part II of the review is focused on a history of developing of memory clinics and Alzheimer's disease centers as well as on the indices of their activity in various countries and in Russia. Approaches to the evaluation of clinical and economic efficacy of new technologies of organization of care and a role of the national programs in solving of the problem of old age dementias were considered.
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28804939/assessing-the-application-of-knowledge-in-clinical-problem-solving-the-structured-professional-reasoning-exercise
#5
M P Escudier, M J Woolford, J A Tricio
INTRODUCTION: Clinical reasoning is a fundamental and core clinical competence of healthcare professionals. The study aimed to investigate the utility of the Structured Professional Reasoning Exercise (SPRE), a new competence assessment method designed to measure dental students' clinical reasoning in simulated scenarios, covering the clinical areas of Oral Disease, Primary Dental Care and Restorative Dentistry, Child Dental Health and Dental Practice and Clinical Governance. MATERIALS AND METHODS: A total of 313 year-5 students sat for the assessment...
August 14, 2017: European Journal of Dental Education: Official Journal of the Association for Dental Education in Europe
https://www.readbyqxmd.com/read/28802152/comparison-and-analysis-of-the-structures-and-binding-modes-of-antifungal-se-and-cyp51-inhibitors
#6
Bin Sun, Wanxu Huang, Min Liu, Kang Lei
With the abuse of clinical broad-spectrum antimicrobial agents, immunosuppressive agents, chemotherapy drugs, the emergence of pathogenic fungi resistance is more and more frequent. However, there is still no effective treatment for the fungal resistance. Squalenee epoxidase (SE) and 14 α-demethylase (CYP51) are important antifungal drug targets. In order to achieve a deeper insight into the structural characteristics and the action modes of SE and CYP51inhibitors, the homology model of SE (Candida albicans) was constructed using monooxygenase of Pseudomonas aeruginosa as template, and the reliability of model was confirmed by Ramachandran plots and Verify 3D...
August 1, 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/28799688/developing-a-program-for-enhancing-youth-hiv-treatment-adherence-and-risk-reduction
#7
Warunee Fongkaew, Warawan Udomkhamsuk, Nongkran Viseskul, Marisa Guptaruk
Youth living with HIV face difficult and challenging situations that decrease their adherence to antiretroviral medications. In this study, we developed a pilot program to enhance HIV treatment adherence and risk reduction among youth living with HIV based on collaboration with a community hospital involving a multi-disciplinary healthcare team. Participants were 25 youth living with HIV/AIDS, 18 caregivers, and 12 healthcare providers. The action research process comprised a preliminary stage and four phases of assessment, planning, implementation, and evaluation...
August 11, 2017: Nursing & Health Sciences
https://www.readbyqxmd.com/read/28798009/preliminary-evaluation-of-a-brief-web-and-mobile-phone-intervention-for-men-with-depression-men-s-positive-coping-strategies-and-associated-depression-resilience-and-work-and-social-functioning
#8
Andrea Susan Fogarty, Judy Proudfoot, Erin Louise Whittle, Janine Clarke, Michael J Player, Helen Christensen, Kay Wilhelm
BACKGROUND: Previous research has identified that men experiencing depression do not always access appropriate health services. Web-based interventions represent an alternative treatment option for men, are effective in reducing anxiety and depression, and have potential for wide dissemination. However, men do not access Web-based programs at the same rate as women. Programs with content explicitly tailored to men's mental health needs are required. OBJECTIVE: This study evaluated the applicability of Man Central, a new Web and mobile phone intervention for men with depression...
August 10, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/28792572/-the-management-of-depression-in-older-adults-and-their-family-caregivers-findings-from-a-research-program-in-quebec
#9
Jane McCusker, Mark Yaffe, Tamara Sussman, Martin Cole, Maida Sewitch, Erin Strumpf, Ellen Freeman, Sylvie Lambert, Manon de Raad
Objectives A research group based at St. Mary's Research Centre, St. Mary's Hospital, Montreal, has conducted a research program over the past two decades that aims to inform improvements in the management of depression in primary care and general medical settings, among older adults. This paper reviews the findings from this research program, discusses the findings in the context of other research, and highlights the implications for practice and health policy.Methods Narrative review and synthesis of 25 published articles, that included: 4 systematic reviews, 10 observational studies, 9 intervention trials, and 2 consensus conference reports...
2017: Santé Mentale Au Québec
https://www.readbyqxmd.com/read/28791314/generation-of-a-vero-based-packaging-cell-line-to-produce-sv40-gene-delivery-vectors-for-use-in-clinical-gene-therapy-studies
#10
Miguel G Toscano, Jeroen van der Velden, Sybrand van der Werf, Machteld Odijk, Ana Roque, Rafael J Camacho-Garcia, Irene G Herrera-Gomez, Irene Mancini, Peter de Haan
Replication-defective (RD) recombinant simian virus 40 (SV40)-based gene delivery vectors hold a great potential for clinical applications because of their presumed non-immunogenicity and capacity to induce immune tolerance to the transgene products in humans. However, the clinical use of SV40 vectors has been hampered by the lack of a packaging cell line that produces replication-competent (RC) free SV40 particles in the vector production process. To solve this problem, we have adapted the current SV40 vector genome used for the production of vector particles and generated a novel Vero-based packaging cell line named SuperVero that exclusively expresses the SV40 large T antigen...
September 15, 2017: Molecular Therapy. Methods & Clinical Development
https://www.readbyqxmd.com/read/28790331/3d-printed-personalized-titanium-plates-improve-clinical-outcome-in-microwave-ablation-of-bone-tumors-around-the-knee
#11
Limin Ma, Ye Zhou, Ye Zhu, Zefeng Lin, Lingling Chen, Yu Zhang, Hong Xia, Chuanbin Mao
Microwave ablation has been widely accepted in treating bone tumor. However, its procedure is time-consuming and usually results in postoperative fractures. To solve this problem, we designed and fabricated titanium plates customized to the patients' bone structures. The personalized titanium plates were then used for fixation after the removal of tumorous tissue. Specifically, 3D models of tumor-bearing bone segments were constructed by using computed tomography (CT) and magnetic resonance imaging (MRI). The 3D models were used to design the personalized titanium plates...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28781756/tiddit-an-efficient-and-comprehensive-structural-variant-caller-for-massive-parallel-sequencing-data
#12
Jesper Eisfeldt, Francesco Vezzi, Pall Olason, Daniel Nilsson, Anna Lindstrand
Reliable detection of large structural variation ( > 1000 bp) is important in both rare and common genetic disorders. Whole genome sequencing (WGS) is a technology that may be used to identify a large proportion of the genomic structural variants (SVs) in an individual in a single experiment. Even though SV callers have been extensively used in research to detect mutations, the potential usage of SV callers within routine clinical diagnostics is hindered by high computational costs, usage of non-standard output format, and limited support for the various sequencing platforms and libraries...
2017: F1000Research
https://www.readbyqxmd.com/read/28776930/early-intervention-for-youth-at-high-risk-for-bipolar-disorder-a-multisite-randomized-trial-of-family-focused-treatment
#13
David J Miklowitz, Christopher D Schneck, Patricia D Walshaw, Amy S Garrett, Manpreet K Singh, Catherine A Sugar, Kiki D Chang
AIMS: Despite the considerable public health impact of bipolar disorder (BD), no psychosocial interventions have been systematically evaluated in its early prodromal stages. We describe the rationale, design and analytic methods for a 3-site randomized trial of family-focused treatment for youth at high risk (FFT-HR) for BD. METHODS: Participants (ages 9-17 years) have a diagnosis of unspecified BD or major depressive disorder, current mood symptoms and at least one first- or second-degree relative with a lifetime history of BD I or II...
August 4, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28774123/floating-hydrogel-with-self-generating-micro-bubbles-for-intravesical-instillation
#14
Tingsheng Lin, Xiaozhi Zhao, Yifan Zhang, Huibo Lian, Junlong Zhuang, Qing Zhang, Wei Chen, Wei Wang, Guangxiang Liu, Suhan Guo, Jinhui Wu, Yiqiao Hu, Hongqian Guo
Intravesical instillation is the main therapy for bladder cancer and interstitial cystitis. However, most drug solutions are eliminated from bladder after the first voiding of urine. To solve this problem, we proposed a floating hydrogel with self-generating micro-bubbles as a new delivery system. It floated in urine, avoiding the urinary obstruction and bladder irritation that ordinary hydrogels caused. In this study, we abandoned traditional gas-producing method like chemical decomposition of NaHCO₃, and used the foamability of Poloxamer 407 (P407) instead...
December 12, 2016: Materials
https://www.readbyqxmd.com/read/28772905/new-challenges-in-tribology-wear-assessment-using-3d-optical-scanners
#15
Maria Cristina Valigi, Silvia Logozzo, Saverio Affatato
Wear is a significant mechanical and clinical problem. To acquire further knowledge on the tribological phenomena that involve freeform mechanical components or medical prostheses, wear tests are performed on biomedical and industrial materials in order to solve or reduce failures or malfunctions due to material loss. Scientific and technological advances in the field of optical scanning allow the application of innovative devices for wear measurements, leading to improvements that were unimaginable until a few years ago...
May 18, 2017: Materials
https://www.readbyqxmd.com/read/28771385/addressing-the-missing-part-of-evidence-based-practice-the-importance-of-respecting-clinical-judgment-in-the-process-of-adopting-a-new-screening-tool-for-postpartum-depression
#16
Vered Ben-David, Melissa Jonson-Reid, Ron Tompkins
The aim of the present study was to examine the role of nurse's clinical judgment in the uptake of an evidence-based tool assessing postpartum depression, the Edinburgh Postpartum Depression Scale. Nurses in a home visitation program were being asked to regularly screen for postpartum depression. The screener was introduced as a new standard of practice for nurses. A qualitative investigation of the nurses' reactions in addition to an evidence-based screener was conducted. Prior to and during the implementation, several meetings were held with the nurses and the research team to discuss the nurses' experience with the tool...
August 3, 2017: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/28768687/hit-ndrive-patient-specific-multidriver-gene-prioritization-for-precision-oncology
#17
Raunak Shrestha, Ermin Hodzic, Thomas Sauerwald, Phuong Dao, Kendric Wang, Jake Yeung, Shawn Anderson, Fabio Vandin, Gholamreza Haffari, Colin C Collins, S Cenk Sahinalp
Prioritizing molecular alterations that act as drivers of cancer remains a crucial bottleneck in therapeutic development. Here we introduce HIT'nDRIVE, a computational method that integrates genomic and transcriptomic data to identify a set of patient-specific, sequence-altered genes, with sufficient collective influence over dysregulated transcripts. HIT'nDRIVE aims to solve the "random walk facility location" (RWFL) problem in a gene (or protein) interaction network, which differs from the standard facility location problem by its use of an alternative distance measure: "multihitting time," the expected length of the shortest random walk from any one of the set of sequence-altered genes to an expression-altered target gene...
July 18, 2017: Genome Research
https://www.readbyqxmd.com/read/28765460/are-dental-schools-part-of-the-safety-net
#18
Howard L Bailit
This article examines the current safety net activities of dental schools and reviews strategies by which schools could care for more poor and low-income patients. The primary data come from the annual Survey of Dental Education, a joint American Dental Education Association (ADEA) and American Dental Association (ADA) activity. The analyses use descriptive statistics and are intended to give ballpark estimates of patients treated under varying clinical scenarios. Some 107.4 million people are underserved in comparison to utilization rates for middle-income Americans...
August 2017: Journal of Dental Education
https://www.readbyqxmd.com/read/28764713/non-iterative-geometric-approach-for-inverse-kinematics-of-redundant-lead-module-in-a-radiosurgical-snake-like-robot
#19
Olatunji Mumini Omisore, Shipeng Han, Lingxue Ren, Nannan Zhang, Kamen Ivanov, Ahmed Elazab, Lei Wang
BACKGROUND: Snake-like robot is an emerging form of serial-link manipulator with the morphologic design of biological snakes. The redundant robot can be used to assist medical experts in accessing internal organs with minimal or no invasion. Several snake-like robotic designs have been proposed for minimal invasive surgery, however, the few that were developed are yet to be fully explored for clinical procedures. This is due to lack of capability for full-fledged spatial navigation. In rare cases where such snake-like designs are spatially flexible, there exists no inverse kinematics (IK) solution with both precise control and fast response...
August 1, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28764679/economic-evaluation-of-stepped-care-versus-usual-care-for-depression-and-anxiety-in-older-adults-with-vision-impairment-randomized-controlled-trial
#20
Hilde P A van der Aa, Ger H M B van Rens, Judith E Bosmans, Hannie C Comijs, Ruth M A van Nispen
BACKGROUND: A stepped-care program was found effective in preventing depressive and anxiety disorders in older adults with vision impairment. However, before a decision can be made about implementation, the cost-effectiveness of this program should be investigated. Therefore, we aimed to compare the cost-effectiveness of stepped-care versus usual care within low vision rehabilitation. METHODS: An economic evaluation from a societal perspective was performed alongside a multicenter randomized controlled trial...
August 1, 2017: BMC Psychiatry
keyword
keyword
26733
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"