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ACL reconstruction and biomechanics

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https://www.readbyqxmd.com/read/28299388/the-combination-of-tibial-anterior-translation-and-axial-rotation-into-a-single-biomechanical-factor-improves-the-prediction-of-patient-satisfaction-over-each-factor-alone-in-patients-with-acl-reconstructed-knees
#1
Thomas P Branch, Shaun K Stinton, William C Hutton, Philippe Neyret
PURPOSE: The purpose of this study was to identify biomechanical factors, in both reconstructed and healthy knees, that correlate with patient satisfaction after ACL reconstruction. METHODS: Seventeen patients who had undergone unilateral ACL reconstruction were reviewed 9 years post-op. Patients completed subjective questionnaires and underwent manual knee laxity testing (Lachman-Trillat, KT-1000, and pivot shift) and automated laxity testing. During automated testing, both legs were rotated into external rotation and then internal rotation until peak rotational torque reached 5...
March 15, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28298055/the-effect-of-graft-pretensioning-on-bone-tunnel-diameter-and-bone-formation-after-anterior-cruciate-ligament-reconstruction-in-a-rat-model
#2
Jian-Chun Zong, Richard Ma, Hongsheng Wang, Guang-Ting Cong, Amir Lebaschi, Xiang-Hua Deng, Scott A Rodeo
BACKGROUND: Moderate graft pretensioning in anterior cruciate ligament (ACL) reconstruction is paramount to restore knee stability and normalize knee kinematics. However, little is known about the effect of graft pretensioning on graft-to-bone healing after ACL reconstruction. HYPOTHESIS: Moderate graft pretensioning will improve bone formation within the bone tunnel after ACL reconstruction, resulting in superior load to failure. STUDY DESIGN: Controlled laboratory study...
February 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28286916/contributions-of-the-anterolateral-complex-and-the-anterolateral-ligament-to-rotatory-knee-stability-in-the-setting-of-acl-injury-a-roundtable-discussion
#3
REVIEW
Volker Musahl, Alan Getgood, Philippe Neyret, Steven Claes, J M Burnham, Cecile Batailler, Bertrand Sonnery-Cottet, Andy Williams, Andrew Amis, Stefano Zaffagnini, Jón Karlsson
Persistent rotatory knee laxity is increasingly recognized as a common finding after anterior cruciate ligament (ACL) reconstruction. While the reasons behind rotator knee laxity are multifactorial, the impact of the anterolateral knee structures is significant. As such, substantial focus has been directed toward better understanding these structures, including their anatomy, biomechanics, in vivo function, injury patterns, and the ideal procedures with which to address any rotatory knee laxity that results from damage to these structures...
March 12, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28282242/influence-of-the-injury-to-surgery-interval-on-the-healing-potential-of-human-anterior-cruciate-ligament-derived-cells
#4
Takao Inokuchi, Tomoyuki Matsumoto, Koji Takayama, Naoki Nakano, Shurong Zhang, Daisuke Araki, Takehiko Matsushita, Ryosuke Kuroda
BACKGROUND: Vascular CD34+ cells in anterior cruciate ligament (ACL) tissue have the potential for high proliferation and multilineage differentiation that can accelerate tendon-bone healing. While patient characteristics, such as age, can affect tendon-bone healing, the influence of elapsed time after injury on the healing process is unclear. HYPOTHESIS: Cells obtained during the early phase after injury will exhibit a greater tendon-bone healing potential compared with chronic phase counterparts when applied to an immunodeficient rat model of ACL reconstruction...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28275205/a-comparative-study-of-effect-of-autograft-versus-allograft-anterior-cruciate-ligament-reconstruction-onexpressions-ofloxsand-mmps
#5
Wei-Ming Wang, Xiao-Jun Ma, Shi-Bo Huang, Liu-Bao Ren, Yu-Peng Liu
This study aimed to compare the effect of autograft or allograft anterior cruciate ligament (ACL) reconstruction on the expressions of LOXs and MMPs in a New Zealand white rabbit model. New Zealand white rabbits were divided randomly into control, sham, autograft and allograft groups At the 4th and 8th week after operation, biomechanical testing was performed to measure the primary length, cross-sectional area, maximum tensile load and stiffness of ACL, and HE staining was used to observe cell morphology and fibre alignment of ACL...
March 8, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28258329/function-and-strain-of-the-anterolateral-ligament-part-i-biomechanical-analysis
#6
Björn Holger Drews, Oliver Kessler, Wolfgang Franz, Lutz Dürselen, Maren Freutel
PURPOSE: Because reconstruction of the anterior cruciate ligament (ACL) in a double-bundle technique did not solve the problem of persistent rotatory laxity after surgery, new potential answers to this issue are of great interest. One of these is an extraarticular stabilization based on the rediscovery of the anterolateral ligament (ALL). Knowledge about its biomechanical function and benchmark data for an optimal reconstruction remain lacking. Therefore, the purpose of this study was to assess the function of the ALL under passive motion, anterior tibial translation and tibial rotational moments...
March 3, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28238964/pullout-strength-of-a-novel-hybrid-fixation-technique-tape-locking-screw-%C3%A2-in-soft-tissue-acl-reconstruction-a-biomechanical-study-in-human-and-porcine-bone
#7
Mark Ayzenberg, Dillon Arango, Grigory E Gershkovich, Praveen S Samuel, Minn Saing
INTRODUCTION: A novel hybrid anterior cruciate ligament(ACL) reconstruction technique known as Tape Locking Screw™ (TLS)is gaining popularity. Utilizing a suspension-type construct in conjunction with an interference screw,thistechnique has demonstrated successful initial clinical results with the use of quadruple hamstring graft. However, there is currently limited data available on the biomechanical strength of this fixation. This study investigates the pullout strength of theconstructin human distal femora as well as in a porcine model...
February 23, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28224442/report-of-the-primary-outcomes-for-gait-mechanics-in-men-of-the-acl-sports-trial-secondary-prevention-with-and-without-perturbation-training-does-not-restore-gait-symmetry-in-men-1-or-2-years-after-acl-reconstruction
#8
Jacob John Capin, Ryan Zarzycki, Amelia Arundale, Kathleen Cummer, Lynn Snyder-Mackler
BACKGROUND: Movement asymmetries during walking are common after anterior cruciate ligament (ACL) injury and reconstruction and may influence the early development of posttraumatic osteoarthritis. Preoperative neuromuscular training (like perturbation training, which is neuromuscular training requiring selective muscle activation in response to surface perturbations) improves gait asymmetries and functional outcomes among people who are ACL-deficient, but the effect of postoperative perturbation training on gait mechanics after ACL reconstruction is unknown...
February 21, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28224072/concomitant-arthroscopic-meniscal-allograft-transplantation-and-anterior-cruciate-ligament-reconstruction
#9
Bryan M Saltzman, Justin W Griffin, Nathan Wetters, Maximilian A Meyer, Brian J Cole, Adam B Yanke
In recent decades, arthroscopic meniscal allograft transplantation (MAT) has been refined as a robust option for the treatment of evolving unicompartmental tibiofemoral arthrosis in the setting of meniscal deficiency. It is imperative that the MAT be performed in a knee with anatomic stability and alignment to reduce aberrant biomechanical forces experienced by the allograft tissue to maintain its durability. Thus, in an anterior cruciate ligament (ACL)-deficient knee, ACL reconstruction (ACLR) must be performed to restore the stable knee environment for the MAT to succeed...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28220268/anterolateral-ligament-expert-group-consensus-paper-on-the-management-of-internal-rotation-and-instability-of-the-anterior-cruciate-ligament-deficient-knee
#10
REVIEW
Bertrand Sonnery-Cottet, Matthew Daggett, Jean-Marie Fayard, Andrea Ferretti, Camilo Partezani Helito, Martin Lind, Edoardo Monaco, Vitor Barion Castro de Pádua, Mathieu Thaunat, Adrian Wilson, Stefano Zaffagnini, Jacco Zijl, Steven Claes
Purpose of this paper is to provide an overview of the latest research on the anterolateral ligament (ALL) and present the consensus of the ALL Expert Group on the anatomy, radiographic landmarks, biomechanics, clinical and radiographic diagnosis, lesion classification, surgical technique and clinical outcomes. A consensus on controversial subjects surrounding the ALL and anterolateral knee instability has been established based on the opinion of experts, the latest publications on the subject and an exchange of experiences during the ALL Experts Meeting (November 2015, Lyon, France)...
February 20, 2017: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/28219088/single-bundle-versus-double-bundle-anterior-cruciate-ligament-reconstruction-a-prospective-randomized-controlled-trial-with-6-year-follow-up
#11
Paolo Adravanti, Francesco Dini, Laura de Girolamo, Massimo Cattani, Michele Attilio Rosa
Single-bundle (SB) anterior cruciate ligament (ACL) reconstruction is increasingly used in a large number of patients and it allows obtaining very good clinical and subjective results; however, functional tests show a persistent rotational instability. Biomechanical studies seem to indicate that double-bundle (DB) ACL reconstruction allows to obtain increased anterior and rotational stability compared with SB. The aim of this prospective randomized controlled study was to compare the clinical outcome and the possible osteoarthritic evolution of patients treated either with a SB (freehand transtibial femoral tunnel) or with a DB technique (outside-in for posterolateral femoral tunnel/inside-out for anteromedial femoral tunnel) at a final follow-up of 6 years...
February 20, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28214894/mechanical-loading-improves-tendon-bone-healing-in-a-rabbit-anterior-cruciate-ligament-reconstruction-model-by-promoting-proliferation-and-matrix-formation-of-mesenchymal-stem-cells-and-tendon-cells
#12
Fanglong Song, Dawei Jiang, Tianchen Wang, Yi Wang, Fengmei Chen, Guoxing Xu, Yifan Kang, Yinquan Zhang
BACKGROUND/AIMS: This study investigated the effect of mechanical stress on tendon-bone healing in a rabbit anterior cruciate ligament (ACL) reconstruction model as well as cell proliferation and matrix formation in co-culture of bone-marrow mesenchymal stem cells (BMSCs) and tendon cells (TCs). METHODS: The effect of continuous passive motion (CPM) therapy on tendon-bone healing in a rabbit ACL reconstruction model was evaluated by histological analysis, biomechanical testing and gene expressions at the tendon-bone interface...
February 16, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28214835/up-regulation-of-tgf-%C3%AE-promotes-tendon-to-bone-healing-after-anterior-cruciate-ligament-reconstruction-using-bone-marrow-derived-mesenchymal-stem-cells-through-the-tgf-%C3%AE-mapk-signaling-pathway-in-a-new-zealand-white-rabbit-model
#13
Rui Wang, Bin Xu, Hong-Gang Xu
BACKGROUND/AIMS: This study aimed to explore the role of TGF-β in tendon-to-bone healing after anterior cruciate ligament (ACL) reconstruction using bone marrow-derived mesenchymal stem cells (BMSCs) through the TGF-β/MAPK signaling pathway in a New Zealand white rabbit model. METHODS: A total of 72 healthy male New Zealand white rabbits were selected for these experiments. Flow cytometry and immunofluorescence were used to detect the expression of BMSC surface markers, and qRT-PCR was performed to detect TGF-β mRNA expression...
January 20, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28211291/a-biomechanical-analysis-of-tibial-acl-reconstruction-with-graft-length-mismatch
#14
Evan B Gaines, Diana Lau, Qais Naziri, Westley Hayes, Julio J Jauregui, Bhaveen H Kapadia, William P Urban, Bashir A Zikria
INTRODUCTION: The incidence of graft length mismatch (GLM) during anterior cruciate ligament (ACL) reconstruction is reported to be up to 13%, with a rate of 20% when using bone-patellar tendon-bone (BPTB) allografts. Multiple techniques have been described to accommodate for the longer BPTB graft. As no study has compared the biomechanical properties of these methods (with cyclic loading), we evaluated the strength of four different surgical techniques used to accommodate for GLM during ACL reconstruction...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28195986/functional-bracing-after-anterior-cruciate-ligament-reconstruction-a-systematic-review
#15
Walter R Lowe, Ryan J Warth, Elizabeth P Davis, Lane Bailey
INTRODUCTION: The purpose of this study was to evaluate the current literature on the use of functional knee braces after anterior cruciate ligament (ACL) reconstruction with respect to clinical and in vivo biomechanical data. METHODS: A systematic search of both the PubMed and Embase databases was performed to identify all studies that reported clinical and/or in vivo biomechanical results of functional bracing versus nonbracing after ACL reconstruction. Extracted data included study design, surgical reconstruction techniques, postoperative rehabilitation protocols, objective outcomes, and subjective outcomes scores...
March 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28195744/-proprietary-processed-allografts
#16
Troy A Roberson, Jeffrey T Abildgaard, Douglas J Wyland, Paul C Siffri, Stephen P Geary, Richard J Hawkins, John M Tokish
BACKGROUND: The processing of allograft tissues in anterior cruciate ligament (ACL) reconstruction continues to be controversial. While high-dose irradiation of grafts has received scrutiny for high failure rates, lower dose irradiation and "proprietary-based" nonirradiated sterilization techniques have become increasingly popular, with little in the literature to evaluate their outcomes. Recent studies have suggested that the specifics of allograft processing techniques may be a risk factor for higher failure rates...
February 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28173988/gender-differences-in-the-restoration-of-knee-joint-biomechanics-during-gait-after-anterior-cruciate-ligament-reconstruction
#17
Makoto Asaeda, Masataka Deie, Naoto Fujita, Yoshifumi Kono, Chiaki Terai, Wataru Kuwahara, Hodaka Watanabe, Hiroaki Kimura, Nobuo Adachi, Toru Sunagawa, Mitsuo Ochi
BACKGROUND: The aim of our study was to evaluate the effects of gender on recovery of knee joint biomechanics over the stance phase of gait after reconstruction of the anterior cruciate ligament (ACL). METHODS: Gait parameters and knee joint kinematics and kinetics were compared in 32 patients (16 male and 16 female) who underwent ACL reconstruction for a unilateral ACL deficiency, with comparison to an age-, height-, and weight-matched Control group. Knee flexion, adduction and tibial rotation angles were measured and knee extension and abduction moment was calculated by inverse dynamics methods...
February 4, 2017: Knee
https://www.readbyqxmd.com/read/28165760/comparison-of-acl-strain-in-the-mcl-deficient-and-mcl-reconstructed-knee-during-simulated-landing-in-a-cadaveric-model
#18
Eric J Mancini, Robert Kohen, Amanda O Esquivel, Allison M Cracchiolo, Stephen Edward Lemos
BACKGROUND: Noncontact anterior cruciate ligament (ACL) injury after valgus landing has been reported and studied biomechanically. However, the role of the medial collateral ligament (MCL) in dissipating these forces has not been fully elucidated. Purpose/Hypothesis: The purpose of this study was to investigate the role that the MCL plays in ACL strain during simulated landing. The hypothesis was that ACL strain would increase significantly in MCL-incompetent knees compared with the native knee and that reconstructing the MCL would return the values to those of the intact knee...
February 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28154888/permanent-knee-sensorimotor-system-changes-following-acl-injury-and-surgery
#19
John Nyland, Collin Gamble, Tiffany Franklin, David N M Caborn
The cruciate ligaments are components of the knee capsuloligamentous system providing vital neurosensory and biomechanical function. Since most historical primary ACL repair attempts were unsuccessful, reconstruction has become the preferred surgery. However, an increased understanding of the efficacy of lesion-site scaffolding, innovative suturing methods and materials, and evolving use of biological healing mediators such as platelet-rich plasma and stem cells has prompted reconsideration of what was once believed to be impossible...
February 2, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28150869/biochemical-markers-of-cartilage-metabolism-are-associated-with-walking-biomechanics-6-months-following-anterior-cruciate-ligament-reconstruction
#20
Brian Pietrosimone, Richard F Loeser, J Troy Blackburn, Darin A Padua, Matthew S Harkey, Laura E Stanley, Brittney A Luc-Harkey, Veronica Ulici, Stephen W Marshall, Joanne M Jordan, Jeffery T Spang
The purpose of our study was to determine the association between biomechanical outcomes of walking gait (peak vertical ground reaction force [vGRF], vGRF loading rate [vGRF-LR], and knee adduction moment [KAM]) 6 months following anterior cruciate ligament reconstruction (ACLR) and biochemical markers of serum type-II collagen turnover (collagen type-II cleavage product to collagen type-II C-propeptide [C2C:CPII]), plasma degenerative enzymes (matrix metalloproteinase-3 [MMP-3]), and a pro-inflammatory cytokine (interleukin-6 [IL-6])...
February 2, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
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