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Colorrectal cancer

Andrea Illán, Jonathan Aires, Laura Quintana
We report the case of a 42-year-old male patient with mucinous-type metastatic colorectal carcinoma of eight years of evolution. He has received multiple lines of cytostatic treatment with acceptable tolerance and without significant impairment in his quality of life. At present, it is estimated that the overall survival of metastatic colon cancer in cytostatic treatment is around 24 months. However, a small subset of patients may present prolonged survivals of 5 to 10 years after diagnosis, revealing heterogeneity of tumor behavior and response to treatment...
September 2017: Revista Española de Enfermedades Digestivas
Thaína Dalla Valle, Ruth Natalia Teresa Turrini, Vanessa de Brito Poveda
Objective: to identify the time between symptoms, the request for care and the beginning of treatment in patients with stomach and colorectal cancer as well as the factors that interfere in these processes. Method: correlational descriptive study, including 101 patients diagnosed with stomach or colorectal cancer, treated in a hospital specialized in oncology. Results: the 101 patients investigated there was predominance of males, mean age of 61...
May 15, 2017: Revista Latino-americana de Enfermagem
Beatriz Escudero Paniagua, Alicia Aguilar-Martínez, Begoña Manuel Keenoy
Introduction :Colorectal cancer (CRC) is the second most common cancer in the Western world. About one million of new CRC cases are diagnosed per year. The survival rate of patients with CRC changes widely, even among patients with the same tumor histology. This is possibly due to the impact of environmental factors on tumor development. The diet is the most important among these factors. It is known that nutrition can modify the risk of CRC. However, the role that nutrition plays in the risk of recurrence or survival in patients with CRC is not known with accuracy...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Alberto MIján de la Torre
El síndrome de caquexia cancerosa es responsable de la muerte de un número significativo de pacientes con cáncer. Se caracteriza por la presencia de una ingesta reducida, con inflamación sistémica y un metabolismo alterado. Los enfermos presentan característicamente una progresiva pérdida de peso y de masa muscular, junto a deterioro funcional. La pérdida muscular se debe a la combinación de reducción de la síntesis proteica con aumento de su degradación. Ello conduce tanto a un acortamiento como a una reducción en el área de la fibra muscular...
June 3, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Rossana Ruiz, Luis Taxa, Eloy F Ruiz, Raúl Mantilla, Luis Casanova, Paola Montenegro
OBJECTIVE: To determine clinicopathological features and prognostic factors among young colorectal cancer (CRC) patients in a Peruvian Cancer Institute. METHODS: Data of patients 40 years or younger, admitted between January 2005 and December 2010, were analyzed. RESULTS: During the study period, 196 young patients with CRC were admitted. The tumor was located in the rectum, left colon and right colon in 45.9%, 28.6% and 25.5% of cases. Family history of CRC was found in 13...
January 2016: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
R Calvo-Rodríguez, F J Montero-Pérez, A García-Olid, E Baena-Delgado, J M Gallardo-Valverde, J M Calderón de la Barca-Gázquez, L M Jiménez-Murillo
BACKGROUND: Intestinal obstruction is one of the most frequent surgical emergencies. Its diagnosis is essentially based on clinical history, physical exploration and image tests. The aim of this study was to analyze the diagnostic value of acute phase reactants in patients with benign versus malign intestinal obstruction. METHOD: Historical cohort study of 53 patients who underwent surgery because of intestinal obstruction and/or non-obstructive colorectal cancer...
April 29, 2016: Anales del Sistema Sanitario de Navarra
María Lourdes Ruiz-Rebollo, Lourdes Del Olmo-Martínez, Benito Velayos-Jiménez, Maria Fe Muñoz, María Álvarez-Quiñones-Sanz, José Manuel González-Hernández
BACKGROUND: Colonoscopy is the gold standard for the detection and prevention of colorectal cancer (CRC). However, some individuals are diagnosed with CRC soon after a previous colonoscopy. AIMS: To evaluate the rate of new onset or missed CRC after a previous colonoscopy and to study potential risk factors. METHODS: Patients in our endoscopy database diagnosed with CRC from March 2004 to September 2011 were identified, selecting those with a colonoscopy performed within the previous 5years...
December 2016: Gastroenterología y Hepatología
F G Marinello, G Baguena, E Lucas, M Frasson, D Hervás, B Flor-Lorente, P Esclapez, A Espí, E García-Granero
AIM: Anastomotic leakage is one of the most feared complications after colonic resection. Many risk factors for anastomotic leakage have been reported, but the impact of an individual surgeon as a risk factor has scarcely been reported. The aim of this study was to assess if the individual surgeon is an independent risk factor for anastomotic leakage in colonic cancer surgery. METHOD: This was a retrospective analysis of prospectively collected data from patients who underwent elective resection for colon cancer with anastomosis at a specialized colorectal unit from January 1993 to December 2010...
June 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
A Croci, A Aleman, A Perez Galan
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
A Croci, A Aleman, A Perez Galan
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Llúcia Benito-Aracil, Gemma Binefa-Rodriguez, Núria Milà-Diaz, M Teresa Lluch-Canut, Montse Puig-Llobet, Montse Garcia-Martinez
OBJECTIVE: To evaluate the impact of an intervention in primary care professionals on their current knowledge about colorectal cancer screening, subsequent surveillance recommendations and referral strategies. METHODS DESIGN: Cluster randomized controlled trial. LOCATION: Primary Care Centers in L'Hospitalet de Llobregat (Barcelona). PARTICIPANTS: Primary Care Professionals (doctors and nurses). INTERVENTION: Training session in six of the 12 centers (randomly selected) about the colorrectal cancer screening program, and three emails with key messages...
September 2015: Enfermería Clínica
Rosalía Sánchez Almaraz, María Martín Fuentes, Samara Palma Milla, Bricia López Plaza, Laura M Bermejo López, Carmen Gómez Candela
INTRODUCTION: Fiber definition includes all those carbohydrates which are not digested nor absorbed in the upper gastrointestinal tract allowing them to reach the colon with no previous processing. Traditionally fiber has been classified according to their solubility into soluble and insoluble and different physiological properties have been defined for each type. The physiologic role of the fiber intake has been studied in diabetes, dyslipidemia or obesity. Fiber intake has also demonstrated to be beneficial in the prevention of many neoplastic diseases like colorectal cancer...
June 1, 2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Raphael Mendonça Guimarães, Paulo Guilherme Molica Rocha, Camila Drumind Muzi, Raquel de Souza Ramos
CONTEXT: Several international studies have observed a correlation between the improvement of socio-demographic indicators and rates of incidence and mortality from cancer of the colon and rectum. OBJECTIVE: The objective of this study is to estimate the correlation between average per capita income and the rate of colorectal cancer mortality in Brazil between 2001 and 2009. METHODS: We obtained data on income inequality (Gini index), population with low incomes (½ infer the minimum wage/month), average family income, per capita ICP and mortality from colon cancer and straight between 2001-2009 by DATASUS...
January 2013: Arquivos de Gastroenterologia
C Castillo-Lancellotti, J A Tur Marí, R Uauy Dagach
BACKGROUND: Observational studies show that folate levels may be associated with the development of adenomas and colorectal cancer, suggesting that folic acid supplementation may have a preventive effect. AIM: Systematic review of scientific evidence from randomized placebo-controlled clinical studies to identify the effects of folic acid supplementation on the recurrence of colorectal adenomas. MATERIAL AND METHODS: Medline via Pubmed systematic review of randomized clinical trials, double-blind and placebo-controlled and references, specifically to evaluate the effect of acid supplementation on the recurrence of colorectal adenomas...
January 2012: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
J Perea, M Lomas, M Hidalgo
Colorectal cancer (CRC) has become a highly relevant condition nowadays. In this respect, advances in the understanding of its molecular basis are key for an adequate management. From the time when the adenoma-carcinoma sequence was formulated as a carcinogenesis model to this day, when -among other things- three major carcinogenic pathways have been identified, the CRC concept has evolved from that of a single disease to the notion that each CRC is a differentiated condition in itself. The suppressor or chromosome instability pathway, the mutator or microsatellite instability pathway, and the methylator or CpG island methylation pathway allow various phenotypes to be identified within CRC...
January 2011: Revista Española de Enfermedades Digestivas
Araceli Málaga López, Dolores Salas Trejo, Teresa Sala Felis, Marta Ponce Romero, Mercedes Goicoechea Sáez, Mercedes Andrés Martínez, Cristóbal Llorens Ivorra, Inmaculada González Serrano
BACKGROUND: Several studies evaluating colorectal cancer (CRC) screening with fecal occult blood testing (FOBT) have reported a significant reduction in mortality from this tumor. The study aims to describe the results of the first round of the CRC screening program in medium-risk population of Valencia and assessing their feasibility and acceptability. METHODS: Colorectal cancer screening pilot study using biennial FOBT. All residents (106,000 Inhabitants) between 50 and 69 years old (a subgroup of 70-74 years), from 3 selected health departments (04, 07 and 13) were invited by mail to participate...
November 2010: Revista Española de Salud Pública
J A González-González, H J Maldonado-Garza, R Flores-Rendón, A A Garza-Galindo
BACKGROUND: The prevalence of colorectal polyps and adenomas in the general population of Mexico is unknown. AIM: To determine the prevalence and risk factors for colorectal polyps detected during flexible sigmoidoscopy (FSIG) in asymptomatic patients. MATERIAL AND METHODS: From 1995 to 2008, FSIG was performed as part of a complete check-up in patients who had lived in northeast Mexico for over 5 years. RESULTS: 946 (794 males/152 females) were included in the study...
October 2009: Revista de Gastroenterología de México
J I Fernández-Blanco Hernáiz, J M Monturiol Jalón
The surgical boarding of Crohn's disease (CD) admitted as a last effort of treatment against behavior in those the therapy prescribes it has failed, it supposes a loss on perspective that can postpone the delay in the recovery of patients and it retracts them of a better quality of life when it is considered that 50% of patients maintain inactive illness during years after selected surgical procedures; some rate no reached by the most effective treatments. The risk to specify surgical procedure in the course of CD rises to 75% of payees, more than 50% in the first year from the diagnosis, and practically 100% patients in the evolution when it is contemplated to attend perianal lesions...
January 2008: Revista Española de Enfermedades Digestivas
David Martínez-Ramos, Javier Escrig-Sos, Juan Manuel Miralles-Tena, Isabel Rivadulla-Serrano, José Luis Salvador-Sanchís
Metastasis to regional lymph nodes, after distant metastasis, is the most important prognostic factor of colorectal carcinomas. It is also of primary importance in decisions related to the administration of adjuvant treatments. Most scientific associations recommend the examination of at least 12 lymph nodes for the reliable determination of the absence of nodal metastases. We performed a literature review on lymph node recovery in order to determine whether 12 is the minimum and optimal number of lymph nodes to be examined after colorrectal cancer surgery...
March 2008: Cirugía Española
J F Noguera Aguilar, C Tortajada Collado, J M Morón Canis, A Plaza Martínez, I Amengual Antich, J J Pujol Tugores
OBJECTIVE: To determine if an experimental model is valid for the study of perianastomotic recurrence in colorectal cancer, comparing it with previous experimental models. METHODS: Experimental study with 40 male Sprague-Dawley rats, assigned to one of the study groups: control group (n = 20), with manipulation of large descending bowel, and colonic anastomosis group (n = 20), with colonic section and colocolic anastomosis. After pharmacological carcinogenesis with 1-2 dimethylhydrazine at a weekly dose of 25 mg/kg for 18 weeks, colonic tumours were studied at the 20th postoperative week...
March 2002: Revista Española de Enfermedades Digestivas
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