keyword
https://read.qxmd.com/read/38330044/compressive-stress-gradients-direct-mechanoregulation-of-anisotropic-growth-in-the-zebrafish-jaw-joint
#21
JOURNAL ARTICLE
Josepha Godivier, Elizabeth A Lawrence, Mengdi Wang, Chrissy L Hammond, Niamh C Nowlan
Mechanical stimuli arising from fetal movements are critical factors underlying joint growth. Abnormal fetal movements negatively affect joint shape features with important implications for joint health, but the mechanisms by which mechanical forces from fetal movements influence joint growth are still unclear. In this research, we quantify zebrafish jaw joint growth in 3D in free-to-move and immobilised fish larvae between four and five days post fertilisation. We found that the main changes in size and shape in normally moving fish were in the ventrodorsal axis, while growth anisotropy was lost in the immobilised larvae...
February 8, 2024: PLoS Computational Biology
https://read.qxmd.com/read/38321398/perinatal-care-and-its-association-with-perinatal-death-among-women-attending-care-in-three-district-hospitals-of-western-uganda
#22
JOURNAL ARTICLE
Mercy Muwema, Joaniter I Nankabirwa, Grace Edwards, Gorrette Nalwadda, Joanita Nangendo, Jaffer Okiring, Gloria Odei Obeng-Amoako, Wilson Mwanja, Elizabeth N Ekong, Joan N Kalyango, Dan K Kaye
BACKGROUND: Provision of effective care to all women and newborns during the perinatal period is a viable strategy for achieving the Sustainable Development Goal 3 targets on reducing maternal and neonatal mortality. This study examined perinatal care (antenatal, intrapartum, postpartum) and its association with perinatal deaths at three district hospitals in Bunyoro region, Uganda. METHODS: A cross-sectional study was conducted in which a questionnaire was administered consecutively to 872 postpartum women before discharge who had attended antenatal care and given birth in the study hospitals...
February 6, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38313973/preterm-prelabour-rupture-of-membrane-pprom-in-a-young-female-in-south-south-nigeria-a-clinical-case-report
#23
Queen L Ekpa, Mfonabasi I Udoudo, Emmanuella I Nwebeh, Obinna C Nwebeh
A 30-year-old in a second pregnancy presented with new-onset spontaneous vaginal discharge of clear liquid for two hours at a gestational age of 29 weeks + 6 days; no other symptoms were present. Movement aggravated vaginal fluid leakage. She appeared anxious but otherwise vitally stable. An immediate ultrasound scan revealed reduced liquor volume. Conservative management was followed by the surgical delivery of a live preterm neonate. The neonate was admitted to the Special Care Baby Unit and the mother was monitored post-surgically in the obstetric ward...
January 2024: Curēus
https://read.qxmd.com/read/38302958/a-case-of-neonatal-tsutsugamushi-disease-diagnosed-with-the-aid-of-rickettsial-macrogenomic-detection
#24
JOURNAL ARTICLE
Xu Yang, Ling Zhang, Shanping Chen, Wei Chen, Yushan Zhang, Yi Zhang, Jialong Liang, Ying Lv, Weiyan Wang, Yini Zhou, Rui Huang, Dongju Pan, Xueyu Li, Qiurong Li
BACKGROUND: Tsutsugamushi, also known as bush typhus, is a naturally occurring disease caused by Orientia tsutsugamushi. We reported a case of vertical mother-to-newborn transmission of Orientia tsutsugamushi infection in a newborn from Yunnan (China). CASE PRESENTATION: Decreased fetal movements were observed at 39 weeks of gestation. After birth, the newborn (female) had recurrent fever, shortness of breath, and bruising around the mouth and extremities. At 5 h 58 min of age, the newborn was admitted for fever, shortness of breath and generalized rash...
February 2, 2024: BMC Pediatrics
https://read.qxmd.com/read/38286496/correction-to-cord-entrapment-in-a-footling-breech-presentation-with-decreased-fetal-movements
#25
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
January 28, 2024: Canadian Medical Association Journal: CMAJ
https://read.qxmd.com/read/38282316/deletion-of-the-sodium-glucose-cotransporter-1-sglt-1-impairs-mouse-sperm-movement
#26
JOURNAL ARTICLE
September Numata, Mumtarin Jannat Oishee, Jeffrey McDermott, Hermann Koepsell, Volker Vallon, Gustavo Blanco
The Sodium Glucose Cotransporter Isoform 1 (Sglt-1) is a symporter that moves Na+ and glucose into the cell. While most studies have focused on the role of Sglt-1 in the small intestine and kidney, little is known about this transporter's expression and function in other tissues. We have previously shown that Sglt-1 is expressed in the mouse sperm flagellum and that its inhibition interferes with sperm metabolism and function. Here, we further investigated the importance of Sglt-1 in sperm, using a Sglt-1 knockout mouse (Sglt-1 KO)...
January 2024: Molecular Reproduction and Development
https://read.qxmd.com/read/38248499/being-pregnant-during-covid-19-exploring-the-covid-19-related-beliefs-behaviors-and-birth-outcome-among-users-of-a-pregnancy-app
#27
JOURNAL ARTICLE
Hui Huang, Olivia Ceavers, Maria Pinzon Iregui, Melissa M Howard
Being pregnant during COVID-19 increases the risk of experiencing severe COVID-19 symptoms, which in turn increases the risk of complications. This study aimed to examine COVID-19-related beliefs, behaviors, and birth outcomes among users of Count the Kicks (CTK), a fetal movement tracking app. This study used the End of Pregnancy Survey data from 1037 CTK users. We used descriptive analyses to analyze COVID-19-related beliefs and behaviors and used the chi-square statistic and Z statistic to examine factors associated with vaccination and birth outcome...
December 26, 2023: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/38239845/a-case-of-a-newborn-with-nemaline-myopathy-from-al-qunfudhah-city-saudi-arabia
#28
Bushra M Alghanmi, Manal M Alghanmi, Mohammed R Alhayli, Randa M Taffour, Safeyah M Alghubayshi
Nemaline myopathy is a primary skeletal muscle disorder and one of the congenital myopathies. It can be caused by mutations in at least 12 genes, with the nebulin ( NEB ) gene being the most common. Here, we present the first case of a neonate with nemaline myopathy from Al-Qunfudhah, Saudi Arabia. A full-term baby boy was delivered via cesarean section due to decreased fetal movement. The baby was covered with a thick meconium stain. He was born with severe distress and underwent an endotracheal tube placement...
January 2024: Curēus
https://read.qxmd.com/read/38237047/maternal-perception-of-decreased-fetal-movements-is-independent-of-infant-size
#29
JOURNAL ARTICLE
R Stoke, K Crawford, L Jardine, S Kumar
OBJECTIVE: Fetal movements are often used as a surrogate for fetal wellbeing. Previous research suggests a link between maternal perception of decreased fetal movements (DFM) and small for gestational age (SGA) infants. The aim of this study was to investigate the association between maternal presentation with DFM and birthweight centile categories at a large Australian perinatal center. METHODS: This was a 5-year cohort study (January 2016 to October 2020) of non-anomalous singleton infants born at the Mater Mothers' Hospital in Brisbane, Australia at 28+0 weeks gestation or later...
January 18, 2024: Ultrasound in Obstetrics & Gynecology
https://read.qxmd.com/read/38224552/prenatal-surgery-in-fetal-myelomeningocele-with-severe-ventriculomegaly
#30
JOURNAL ARTICLE
M D Mitts, W Whitehead, R Corroenne, R Johnson, R Donepudi, J Espinoza, A A Shamshirsaz, M Sanz Cortes, M A Belfort, A A Nassr
OBJECTIVES: Prenatal myelomeningocele (MMC) repair is performed to decrease risk for treatment of hydrocephalus after birth and to preserve motor function. Some centers may not consider patients candidates for surgery if severe ventriculomegaly is present and there is no expected benefit in decreased risk for hydrocephalus treatment. This study sought to compare postnatal outcomes of fetuses with MMC and severe ventriculomegaly (>15mm) who underwent prenatal repair, with fetuses with severe ventriculomegaly who underwent postnatal repair and fetuses with ventriculomegaly (<15mm) who underwent prenatal repair...
January 15, 2024: Ultrasound in Obstetrics & Gynecology
https://read.qxmd.com/read/38212680/the-effects-of-lockdown-during-the-covid-19-pandemic-on-fetal-movement-profiles
#31
JOURNAL ARTICLE
N Reissland, B Ustun, J Einbeck
PURPOSE: The current study investigated the direct impact of the COVID-19 lockdown on fetal movements, addressing a critical research gap. While previous research has predominantly examined the effects of lockdown on maternal health and postnatal outcomes, little attention has been paid to the direct consequences on fetal well-being as indicated by their movement profile. METHODS: We conducted analysis of movement profiles in 20 healthy fetuses during the COVID-19 pandemic lockdown (third national UK lockdown period between January and March 2021) and compared them with 20 healthy fetuses from pre-covid pregnancies, all at 32 weeks gestation...
January 11, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38187266/-scn4a-related-congenital-myopathy-in-a-han-chinese-patient-a-case-report-and-literature-review
#32
Tina Yee-Ching Chan, Ling-Yin Hung, Tiffany Yan-Lok Lam, Bun Sheng, Frank Ying-Kit Leung, Hencher Han-Chih Lee
SCN4A mutations have been shown to be associated with myotonia, paramyotonia congenita, and periodic paralyses. More recently, loss-of-function variants in the SCN4A gene were also noted to be associated with rarer, autosomal recessive forms of congenital myasthenic syndrome and congenital myopathy. Diagnosis is challenging as the initial clinical presentation and histological features on muscle biopsies are non-specific. We report a Han Chinese patient presented with congenital myopathy with two missense SCN4A variants...
January 15, 2024: Heliyon
https://read.qxmd.com/read/38186821/factors-associated-with-the-knowledge-of-obstetric-danger-signs-among-pregnant-women-attending-primary-health-care-antenatal-care-clinics-in-abha-city
#33
JOURNAL ARTICLE
Ayoub Ali Alshaikh, Ahmed Shubayli Assiri, Fatima Riaz, Saleh Ahmed Alshaikhi, Abdullah Ali Alarrafi, Rishi K Bharti, Syed Esam Mahmood, Shehata Farag
INTRODUCTION: Knowledge of obstetric danger signs would equip women to make the right decisions and appropriate actions timely to have better health care assistance which will impose a significant impact on maternal mortality and morbidity. Hence, this study aimed to know the factors associated with the knowledge of obstetric danger signs among pregnant women who attend the primary health care clinics, which is considered as the first gate to seek health care for pregnant women during antenatal checkups...
November 2023: Journal of Family Medicine and Primary Care
https://read.qxmd.com/read/38161182/a-call-for-early-detection-of-cerebral-palsy
#34
JOURNAL ARTICLE
Faith Kim, Nathalie Maitre
Cerebral palsy (CP) is the most common physical disability across the lifespan, but historically, CP has not been diagnosed before the age of 2 years. Barriers to early diagnosis ranged from lack of available biomarkers, absence of curative treatments, perceived stigma associated with a lifelong diagnosis, and a desire to rule out other diagnoses first. Most importantly, the fundamental question that remained was whether children would benefit from earlier detection and intervention given the paucity of research...
January 1, 2024: NeoReviews
https://read.qxmd.com/read/38152001/prenatal-characterization-of-novel-neurosonographic-findings-in-a-fetus-with-sotos-syndrome
#35
Eran Bornstein, Sarah Reiss, Gustavo Malinger
Sotos syndrome is a rare genetic disorder that occurs in less than 1 in 10,000 births. It is characterized by rapid growth during childhood (tall stature and unusually large head), typical facial dysmorphic features, neurodevelopmental delays of both mental and movement abilities, and learning disabilities. Prenatal diagnosis of Sotos syndrome is infrequent and sonographic findings are not well characterized as the condition is generally detected during childhood. We present a case in which routine third trimester ultrasound detected intracranial findings including ventriculomegaly, periventricular pseudocysts, and increased periventricular echogenicity...
December 27, 2023: Prenatal Diagnosis
https://read.qxmd.com/read/38148006/biallelic-truncating-ttn-variants-in-m-band-encoding-exons-cause-a-fetal-lethal-titinopathy
#36
Ming-Wei Li, Fan Li, Zhen-Xing Cheng, Jin Cheng, Quan Wu, Zhi-Xin Wang, Fei Wang, Ping Zhou
To report two novel TTN variants associated with fetal recessive titinopathy, thereby broadening the range of TTN variants that can lead to titinopathy. Clinical information on the fetus and parents was gathered, and genomic DNAs were extracted from the fetal tissue and family members' peripheral blood samples. Exome sequencing on fetal DNA was performed and following bioinformatics analysis, the suspected pathogenic variants were confirmed through Sanger sequencing. Prenatal ultrasound performed at 29 weeks of gestation revealed hydrops fetalis, decreased fetal movements, multiple joint contractures and polyhydramnios...
December 26, 2023: Prenatal Diagnosis
https://read.qxmd.com/read/38146963/the-role-and-outcomes-of-music-therapy-during-pregnancy-a-systematic-review-of-randomized-controlled-trials
#37
REVIEW
Chao Ji, Jing Zhao, Qiaole Nie, Shuo Wang
INTRODUCTION: The abundant functions of music and its effects on human's mental and physical health have been verified since ancient times, but rarely received attention as an alternative obstetric intervention. OBJECTIVE: This study aims to investigate the benefits of music therapy on prenatal and delivery experiences of pregnant women. METHOD: A systematic search for articles was conducted in electronic databases including CINAHL, Web of Science, PubMed/Medline, and CNKI...
December 2024: Journal of Psychosomatic Obstetrics and Gynaecology
https://read.qxmd.com/read/38127050/decreased-fetal-movement-awhonn-practice-brief-20
#38
(no author information available yet)
No abstract text is available yet for this article.
December 20, 2023: Nursing for Women's Health
https://read.qxmd.com/read/38127036/decreased-fetal-movement-awhonn-practice-brief-20
#39
(no author information available yet)
No abstract text is available yet for this article.
December 20, 2023: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://read.qxmd.com/read/38126076/case-report-one-case-of-umbilical-vein-thrombosis-in-the-second-trimester-with-associated-portal-vein-thrombosis-after-childbirth
#40
Wei-Wei Dai, Qi-Shu Hou, Lian-Hua Yang, Shang-Qin Chen, Ji-Feng Ye
BACKGROUND: Umbilical vein thrombosis is a rare pregnancy complication, that is difficult to detect prenatally but can lead to poor fetal outcomes. CASE PRESENTATION: We described a 33-year-old primiparae who was identified as having umbilical vein thrombosis by ultrasound at 21 weeks gestation, and the neonate was found to have a portal vein thrombus after delivery. Following enoxaparin anticoagulant therapy, the thrombus disappeared within 4 weeks...
2023: Frontiers in Medicine
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