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Dermatopathology

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https://www.readbyqxmd.com/read/29770788/training-avenues-in-dermatopathology-for-an-indian-dermatologist-or-pathologist
#1
Sherina Laskar
No abstract text is available yet for this article.
May 17, 2018: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/29770463/a-first-for-dermatopathology-and-pathology-in-general-appropriate-use-criteria-in-dermatopathology-from-the-american-society-of-dermatopathology
#2
Adam I Rubin, Michael Hitchcock
In this issue of the Journal of Cutaneous Pathology(1), the ASDP Appropriate Use Criteria (AUC) Task Force releases a landmark series of recommendations on AUC from the American Society of Dermatopathology. This is the first set of AUC in dermatopathology and, indeed, in pathology overall. These recommendations were developed as part of the work of the ASDP AUC Task Force, created in 2015. This publication provides strong, evidence-based recommendations that will improve the delivery and utilization of care for our patients, just as AUC for Mohs surgery have elevated the discourse on that procedure for the benefit of patients and society as a whole(2)...
May 17, 2018: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29719023/maximizing-the-clinical-utility-of-descriptive-lymphoid-pathology-reporting
#3
Timothy H McCalmont
Dermatopathology reporting can be both exact and inexact. Exact reporting represents the use of terminology that corresponds to a disease sui generis, such as discoid lupus erythematosus or disseminated superficial porokeratosis. Inexact reporting can vary greatly amongst various practitioners-both in terms of the exact semantics used and also stylistically-and can be used habitually by pathologists as a means to provide cover for diagnostic uncertainty or inexperience. This article explores the use of descriptive (inexact) reporting as it applies to cutaneous lymphoma and its differential diagnosis...
March 2018: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29717505/diagnostic-accuracy-of-whole-slide-imaging-for-cutaneous-soft-tissue-and-melanoma-sentinel-lymph-node-biopsies-with-and-without-immunohistochemistry
#4
Michael R Sargen, Kevin M Luk, Benjamin K Stoff, Jaime MacKelfresh, Samit Patrawala, Chao Zhang, David Gutman, Suephy C Chen
Skin biopsies requiring expert dermatopathology review are likely to increase in future years as a result of an aging U.S. population, which is projected to significantly increase demand for dermatologic care.(1-4) As a result, differentiating between benign and malignant cutaneous neoplasms or evaluating an inflammatory condition may require consultation with dermatopathologists at distant laboratories.
May 1, 2018: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29689323/appropriate-use-criteria-in-dermatopathology-initial-recommendations-from-the-american-society-of-dermatopathology
#5
Claudia I Vidal, Eric A Armbrect, Aleodor A Andea, Angela K Bohlke, Nneka I Comfere, Sarah R Hughes, Jinah Kim, Jessica A Kozel, Jason B Lee, Konstantinos Linos, Brandon R Litzner, Tricia A Missall, Roberto A Novoa, Uma Sundram, Brian L Swick, M Yadira Hurley, Murad Alam, Zsolt Argenyi, Lyn M Duncan, Dirk M Elston, Patrick O Emanuel, Tammie Ferringer, Maxwell A Fung, Gregory A Hosler, Alexander J Lazar, Lori Lowe, Jose A Plaza, Victor G Prieto, June K Robinson, Andras Schaffer, Antonio Subtil, Wei-Lien Wang
BACKGROUND: Appropriate use criteria (AUC) provide physicians guidance in test selection, can affect health care delivery, reimbursement policy, and physician decision-making. OBJECTIVES: The American Society of Dermatopathology (ASDP), with input from the American Academy of Dermatology (AAD) and the College of American Pathologists (CAP), sought to develop AUC in dermatopathology. METHODS: The RAND/UCLA appropriateness methodology, which combines evidence-based medicine, clinical experience and expert judgment, was used to develop AUC in dermatopathology...
April 21, 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29669194/racial-disparities-in-the-incidence-of-primary-chronic-cutaneous-lupus-erythematosus-in-the-southeastern-united-states-the-georgia-lupus-registry
#6
Cristina Drenkard, Sareeta Parker, Laura D Aspey, Caroline Gordon, Charles G Helmick, Gaobin Bao, S Sam Lim
OBJECTIVE: Relative to SLE, epidemiologic studies on chronic cutaneous lupus erythematosus (CCLE) are rare and limited to populations without racial diversity. We sought to provide minimum estimates of the incidence of primary CCLE (CCLE in absence of SLE) in a predominantly white and black population in the Southestern United States. METHODS: The Georgia Lupus Registry used multiple sources for case finding, including dermatology and rheumatology practices, multispecialty healthcare facilities, and dermatopathology reports...
April 18, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29660167/muse-microscopy-with-uv-surface-excitation-a-novel-approach-to-real-time-inexpensive-slide-free-dermatopathology
#7
Amir Qorbani, Farzad Fereidouni, Richard Levenson, Sana Yasmine Lahoubi, Zachary T Harmany, Austin Todd, Maxwell A Fung
Traditional histology relies on processing and physically sectioning either frozen or formalin-fixed, paraffin-embedded (FFPE) tissue into thin slices (typically 4-6 microns) prior to staining and viewing on a standard wide-field microscope. MUSE represents a novel alternative microscopy method that works with ultraviolet (UV) excitation using oblique cis-illumination which can generate high-quality images from the cut surface of fresh or fixed tissue after brief staining, with no requirement for fixation, embedding and histological sectioning of tissue specimens...
April 16, 2018: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29649007/practice-of-teledermatopathology-a-systematic-review
#8
Jasmine Saleh
INTRODUCTION: Teledermatopathology has the potential to revolutionize the practice of diagnosing skin diseases. This review provides an overview of the advantages, limitations, and future directions of teledermatopathology. METHODS: MEDLINE was searched via PubMed and Google Scholar databases for relevant articles published from 2012 to the present. Additional articles were also identified by hand-searching. RESULTS: A total of 2675 citations were identified in the initial search...
April 11, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29570132/xanthomatous-cells-in-cutaneous-graft-versus-host-disease-biopsies-a-clue-for-the-diagnosis-of-hepatic-graft-versus-host-disease
#9
Denise Gamé, Lucia López, Concepción Román, Ángel Santos-Briz
Graft-versus-host disease (GVHD) is one of the most common and serious complications of hematopoietic stem-cell transplantation that mainly affects the skin, gastrointestinal tract, and liver. Hepatic GVHD is associated with high morbidity and mortality, and its diagnosis can be especially challenging because of nonspecific clinical signs and symptoms. It must be suspected in patients with elevated liver enzymes and cholestasis, especially in those with a history of preceding skin rash and diarrhea. We describe 3 patients with cutaneous and hepatic GVHD that presented with severe hypercholesterolemia and hypertriglyceridemia, and no xanthomatous macular lesions, in which cutaneous biopsies revealed the presence of xanthomatous dermal histiocytes...
March 21, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29566273/appropriate-use-criteria-in-dermatopathology-initial-recommendations-from-the-american-society-of-dermatopathology
#10
Claudia I Vidal, Eric A Armbrect, Aleodor A Andea, Angela K Bohlke, Nneka I Comfere, Sarah R Hughes, Jinah Kim, Jessica A Kozel, Jason B Lee, Konstantinos Linos, Brandon R Litzner, Tricia A Missall, Roberto A Novoa, Uma Sundram, Brian L Swick, M Yadira Hurley, Murad Alam, Zsolt Argenyi, Lyn M Duncan, Dirk M Elston, Patrick O Emanuel, Tammie Ferringer, Maxwell A Fung, Gregory A Hosler, Alexander J Lazar, Lori Lowe, Jose A Plaza, Victor G Prieto, June K Robinson, Andras Schaffer, Antonio Subtil, Wei-Lien Wang
BACKGROUND: Appropriate use criteria (AUC) provide physicians guidance in test selection, can affect health care delivery, reimbursement policy, and physician decision-making. OBJECTIVES: The American Society of Dermatopathology (ASDP), with input from the American Academy of Dermatology (AAD) and the College of American Pathologists (CAP), sought to develop AUC in dermatopathology. METHODS: The RAND/UCLA appropriateness methodology, which combines evidence-based medicine, clinical experience and expert judgment, was used to develop AUC in dermatopathology...
March 22, 2018: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29561332/abstracts-presented-at-the-20th-joint-meeting-of-the-international-society-of-dermatopathology-march-1-2-2017-hilton-orlando-lake-buena-vista-in-the-walt-disney-world-resort-lake-buena-vista-florida-usa-erratum
#11
https://www.readbyqxmd.com/read/29551808/uscap-2018-abstracts-dermatopathology-524-585
#12
(no author information available yet)
No abstract text is available yet for this article.
March 2018: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/29551783/uscap-2018-abstracts-dermatopathology-524-585
#13
(no author information available yet)
No abstract text is available yet for this article.
March 2018: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/29533275/38th-symposium-of-the-international-society-of-dermatopathology
#14
Wolfgang Weyers, Dieter Metze
No abstract text is available yet for this article.
February 26, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29524584/pathologist-characteristics-associated-with-accuracy-and-reproducibility-of-melanocytic-skin-lesion-interpretation
#15
David E Elder, Michael W Piepkorn, Raymond L Barnhill, Gary M Longton, Heidi D Nelson, Stevan R Knezevich, Margaret S Pepe, Patricia A Carney, Linda J Titus, Tracy Onega, Anna N A Tosteson, Martin A Weinstock, Joann G Elmore
BACKGROUND: Diagnostic interpretations of melanocytic skin lesions vary widely among pathologists, yet the underlying reasons remain unclear. OBJECTIVE: Identify pathologist characteristics associated with rates of accuracy and reproducibility. METHODS: Pathologists independently interpreted the same set of biopsy specimens from melanocytic lesions on 2 occasions. Diagnoses were categorized into 1 of 5 classes according to the Melanocytic Pathology Assessment Tool and Hierarchy for Diagnosis system...
March 7, 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29524457/factors-related-to-nevus-associated-cutaneous-melanoma-a-case-case-study
#16
Nirmala Pandeya, Marina Kvaskoff, Catherine M Olsen, Adèle C Green, Susan Perry, Catherine Baxter, Marcia B Davis, Rohan Mortimore, Lorraine Westacott, Dominic Wood, Joe Triscott, Richard Williamson, David C Whiteman
A proportion of cutaneous melanomas display neval remnants on histologic examination. Converging lines of epidemiologic and molecular evidence suggest that melanomas arising from nevus precursors differ from melanomas arising de novo. In a large, population-based study comprising 636 cutaneous melanomas subjected to dermatopathology review, we explored the molecular, host, and environmental factors associated with the presence of neval remnants. We found that nevus-associated melanomas were significantly associated with younger age at presentation, non-brown eye color, trunk site, thickness of less than 0...
March 7, 2018: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29496200/-why-don-t-they-ever-call-expectations-of-clinicians-and-pathologists-regarding-the-communication-of-critical-diagnoses-in-dermatopathology
#17
Jasmin Dvorah Korbl, Benjamin Andrew Wood, Nathan Tobias Harvey
Certain diagnoses in dermatopathology have significant implications for patient management and on occasion appropriate clinical care may be facilitated by a phone call from the reporting dermatopathologist to the referring doctor. Whether this is appropriate depends on a number of factors. The concept of 'critical diagnoses' is now well established in surgical pathology, having evolved from critical value policies in clinical pathology and haematology. However, only limited attempts have been made to assess perceptions among different clinical groups...
April 2018: Pathology
https://www.readbyqxmd.com/read/29489509/the-amount-of-melanin-influences-p16-loss-in-spitzoid-melanocytic-lesions-correlation-with-cdkn2a-status-by-fish-and-mlpa
#18
Carolina Martinez Ciarpaglini, Jose Gonzalez, Beatriz Sanchez, Jaime Agusti, Lara Navarro, Gema Nieto, Carlos Monteagudo
AIMS: The risk assessment of spitzoid lesions is one of the most difficult challenges in dermatopathology practice. In this regard, the loss of p16 expression and the homozygous deletion of CDKN2A, have been pointed in the literature as reliable indicators of high risk. However, these findings are poorly reproducible, and the molecular bases underlying the loss of p16 expression remain unclear. We aimed to identify the underlying events causing loss of CDKN2A/p16 in spitzoid tumors. MATERIALS AND METHODS: We evaluated the immunohistochemical expression of p16, and the presence of CDKN2A genetic alterations detected through fluorescence in situ hybridization (FISH) and multiplex ligation-dependent probe amplification (MLPA), in a series of 130 Spitz nevi, 20 atypical spitzoid tumors, and 11 spitzoid melanoma...
February 27, 2018: Applied Immunohistochemistry & Molecular Morphology: AIMM
https://www.readbyqxmd.com/read/29470303/clues-in-histopathological-diagnosis-of-panniculitis
#19
Mar Llamas Velasco, Yosmar Carolina Pérez-Gónzalez, Werner Kempf, Bruno Emilio Paredes, Lorenzo Cerroni, María Teresa Fernández Figueras
BACKGROUND: Panniculitides comprise a group of heterogeneous inflammatory diseases. Nevertheless, histopathological study along with clinicopathological correlation usually led to a specific diagnosis. In most textbooks, the first step in the diagnosis is to classify them as mostly septal or lobular depending on where the inflammatory infiltrate is located. The second step is deciding if vasculitis is present or not. Finally, the third step is further characterizing the inflammatory infiltrate...
March 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29436726/molecular-testing-practices-and-perceptions-among-dermatopathologists
#20
Kristin Torre, Preeti Jhorar, Rong Wu, John Pfeifer, Zendee Elaba, Michael Murphy
BACKGROUND: We evaluated how dermatopathologists are employing molecular testing in the setting of neoplastic skin diseases, and assessed their opinions of the broader role and utility of molecular technologies in clinical practice. METHODS: A 15-question online survey was sent to Fellows of the American Society of Dermatopathology in April 2017. RESULTS: One hundred and thirty-six dermatopathologists completed the survey (response rate = 16%)...
February 13, 2018: Journal of Cutaneous Pathology
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