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Dermatopathology

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https://www.readbyqxmd.com/read/29340950/dermatologic-lesions-submitted-to-an-oral-and-maxillofacial-pathology-biopsy-service-an-analysis-of-2487-cases
#1
Rekha Reddy, Liya Davidova, Indraneel Bhattacharyya, Donald M Cohen, Mohammed N Islam, Sarah G Fitzpatrick
Skin lesions are often submitted to oral and maxillofacial pathology practices. The purpose of this study is to evaluate the frequency, distribution, variability, and composition of dermatologic lesions within a large oral and maxillofacial pathology biopsy service. An IRB-approved retrospective search of skin lesions diagnosed at University of Florida oral and maxillofacial pathology biopsy service between 1994 and 2015 was performed. 2487 cases were included in the study. Gender was reported in 2466 cases, of which 59% were male and 41% female...
January 16, 2018: Head and Neck Pathology
https://www.readbyqxmd.com/read/29286213/risk-factors-for-invasive-fungal-infection-among-thai-oncologic-patients-with-febrile-neutropenia-and-cutaneous-presentation-a-5-year-retrospective-study-in-southern-thailand
#2
Kumpol Aiempanakit, Surarit Naorungroj, Kanokphorn Chiratikarnwong, Sauvarat Auepemkiate, Benjawan Apinantriyo
Background: Febrile neutropenia (FNP) is a condition defined by fever and neutropenia. There are current only limited data on related cutaneous manifestations. This study aimed to assess cutaneous lesions and their etiologies in a Thai group of FNP patients. Methods: A retrospective analysis was conducted on 43 non-transplant febrile neutropenic patients with concurrent cutaneous lesions, as determined by dermatopathologic studies at Songklanagarind Hospital in Thailand over a five-year period. Results: The mean age was 39 years (SD: 18...
December 29, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29282435/efficient-cancer-detection-using-multiple-neural-networks
#3
John Shell, William D Gregory
The inspection of live excised tissue specimens to ascertain malignancy is a challenging task in dermatopathology and generally in histopathology. We introduce a portable desktop prototype device that provides highly accurate neural network classification of malignant and benign tissue. The handheld device collects 47 impedance data samples from 1 Hz to 32 MHz via tetrapolar blackened platinum electrodes. The data analysis was implemented with six different backpropagation neural networks (BNN). A data set consisting of 180 malignant and 180 benign breast tissue data files in an approved IRB study at the Aurora Medical Center, Milwaukee, WI, USA, were utilized as a neural network input...
2017: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/29282184/compromising-patient-care-gross-payment-disparities-in-dermatopathology-part-ii
#4
Viral M Patel, Divya Sharma, Michael Sylvester, Christina Ring, Jose D Espinal-Mariotte, W Clark Lambert
No abstract text is available yet for this article.
2017: Skinmed
https://www.readbyqxmd.com/read/29251638/correlation-of-reflectance-confocal-microscopy-and-dermatopathology-findings-in-a-case-of-acrodermatitis-chronica-atrophicans
#5
Duygu Gülseren, Lorenzo Cerroni, Rainer Hofmann-Wellenhof, Edith Arzberger
Acrodermatitis chronica atrophicans (ACA) that is characterized by thin, papery dry, translucent, and alopecic patches with visible superficial veins is a late cutaneous manifestation of Lyme borreliosis. Clinical findings, a history of exposure to tick bite, and serology are helpful for the diagnosis of ACA and sometimes a biopsy is performed to rule out other infectious or inflammatory processes. In this study, we report reflectance confocal microscopy (RCM) findings in a case of ACA. RCM examination revealed a flattened surface with broadened skin folds, a flattened dermoepidermal junction with few papillae and less bright basal cells and multiple small bright reflecting spots in the dermis...
November 29, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29246825/mohs-micrographic-surgery-and-dermatopathology-concordance-an-analysis-of-1421-mohs-cases-over-17-years
#6
Katarina Kesty, Omar P Sangueza, Barry Leshin, John G Albertini
BACKGROUND: The success of Mohs micrographic surgery depends on the surgeon's ability to correctly interpret intraoperative frozen sections. OBJECTIVE: This retrospective study analyzed the rate of concordance between Mohs surgeons and dermatopathologists in reading slides from Mohs surgery cases. METHODS: A dermatopathologist reviewed all the frozen sections and the corresponding Mohs map for every 30th Mohs case at a practice employing 6 different Mohs surgeons from 2001-2017...
December 12, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29238799/association-of-clinical-dermoscopic-and-histopathologic-findings-with-gene-expression-in-patients-with-balloon-cell-melanoma
#7
Ben J Friedman, Rebecca Stoner, Joya Sahu, Jason B Lee
Importance: Balloon cell melanoma is a rare subtype of melanoma that is underrecognized clinically and is challenging to diagnose on histologic studies. Objective: To further characterize the clinical, dermoscopic, and histopathologic features of balloon cell melanomas and their correlation to gene expression. Design, Setting, and Participants: Case series of 2 patients with balloon cell melanoma whose medical records were retrieved from the database of Thomas Jefferson University Dermatopathology Center in Philadelphia, Pennsylvania...
December 13, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/29196359/inherited-skin-tumour-syndromes
#8
Sarah Brown, Paul Brennan, Neil Rajan
This article provides an overview of selected genetic skin conditions where multiple inherited cutaneous tumours are a central feature. Skin tumours that arise from skin structures such as hair, sweat glands and sebaceous glands are called skin appendage tumours. These tumours are uncommon, but can have important implications for patient care. Certain appendageal tumours, particularly when multiple lesions are seen, may indicate an underlying genetic condition. These tumours may not display clinical features that allow a secure diagnosis to be made, necessitating biopsy and dermatopathological assessment...
December 2017: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29188286/association-of-dermatologist-density-with-the-volume-and-costs-of-dermatology-procedures-among-medicare-beneficiaries
#9
Sally Y Tan, Daphne Tsoucas, Arash Mostaghimi
Importance: The persistent shortage of dermatologists in the United States affects access to care and patient outcomes. Objective: To characterize the effect of geographic variations in dermatologist density on the provision of dermatology procedures within Medicare. Design, Setting, and Participants: This was a cross-sectional study using the 2013 Medicare Provider Utilization and Payment Database. Dermatology-related procedures were defined by the top 50 billing codes accounting for more than 95% of procedures billed by dermatologists...
November 29, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/29160213/cutaneous-metastases-of-internal-malignancies-an-experience-from-a-single-institution
#10
Elena Guanziroli, Antonella Coggi, Luigia Venegoni, Daniele Fanoni, Giulia Ercoli, Francesca Boggio, Stefano Veraldi, Emilio Berti, Raffaele Gianotti, Stefano Ferrero, Alessandro Del Gobbo
BACKGROUND: Cutaneous metastases represent 2% of all skin tumours. Their recognition can be challenging, as they may present with different clinical features, with consequent frequent delay and failure in diagnosis. OBJECTIVES: To review our series of cutaneous metastatic lesions, analyse their frequency according to patient gender, histotype, localization of the primary tumour, and site of cutaneous metastasis, and correlate this data with clinicopathological parameters...
November 21, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/29139366/compromising-patient-care-gross-payment-disparities-in-dermatopathology-part-i
#11
Viral M Patel, Divya Sharma, Michael Sylvester, Fernanda Salgado, Stephen Peters, W Clark Lambert
No abstract text is available yet for this article.
2017: Skinmed
https://www.readbyqxmd.com/read/29090469/multiple-epidermolytic-acanthomas-mimicking-condyloma-a-retrospective-study-of-8-cases
#12
Tsung-Ju Lee, Yu-Hung Wu
BACKGROUND: Epidermolytic acanthoma (EA) is an uncommon benign cutaneous lesion. Multiple epidermolytic acanthomas (multiple EAs) are rarely reported. METHODS: We retrospectively identified patients diagnosed with multiple EAs between 2005 and 2017 from our dermatopathology database and analyzed their clinical, pathological, and immunohistochemical features. We also evaluated the association of multiple EAs with human papillomavirus (HPV) infection. RESULTS: In total, eight patients (average age 51 years; 3 : 1 male predominance) with multiple EAs were found...
October 31, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/29084365/views-of-dermatopathologists-about-clonality-assays-in-the-diagnosis-of-cutaneous-t-cell-and-b-cell-lymphoproliferative-disorders
#13
REVIEW
Nneka Comfere, Uma Sundram, Maria Yadira Hurley, Brian Swick
BACKGROUND: Appropriate use criteria have been developed for many tests using expert judgment, evidence-based practice and clinical experience. In this context, we report the opinions of practitioners about clonality assays in various clinical scenarios where cutaneous lymphoma is suspected. METHODS: An Appropriate Use Criteria Task Force sponsored by the American Society of Dermatopathology (ASDP) synthesized clinical scenarios for cutaneous lymphoproliferative disorders (LPDs)...
January 2018: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29077578/measuring-scholastic-production-by-dermatopathologists-using-the-h-index-a-cross-sectional-study
#14
Garth R Fraga
Academic advancement in dermatopathology requires evidence of scientific production. The H-index is a useful bibliometric for measuring scientific production because it weights both volume and impact of an individual's scholastic production. The H-index distribution among academic dermatopathologists is unknown. In this cross-sectional study of 299 dermatopathologists with academic appointments in North America, H-index, publication counts, and citation counts were retrieved from Thomas Reuters Web of Science...
October 16, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29072946/histologic-mimics-of-basal-cell-carcinoma
#15
REVIEW
Lauren M Stanoszek, Grace Y Wang, Paul W Harms
CONTEXT: - Basal cell carcinoma (BCC) is the most common human malignant neoplasm and is a frequently encountered diagnosis in dermatopathology. Although BCC may be locally destructive, it rarely metastasizes. Many diagnostic entities display morphologic and immunophenotypic overlap with BCC, including nonneoplastic processes, such as follicular induction over dermatofibroma; benign follicular tumors, such as trichoblastoma, trichoepithelioma, or basaloid follicular hamartoma; and malignant tumors, such as sebaceous carcinoma or Merkel cell carcinoma...
November 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29049424/diagnostic-accuracy-of-virtual-pathology-vs-traditional-microscopy-in-a-large-dermatopathology-study
#16
Michael N Kent, Thomas G Olsen, Theresa A Feeser, Katherine C Tesno, John C Moad, Michael P Conroy, Mary Jo Kendrick, Sean R Stephenson, Michael R Murchland, Ayesha U Khan, Elizabeth A Peacock, Alexa Brumfiel, Michael A Bottomley
Importance: Digital pathology represents a transformative technology that impacts dermatologists and dermatopathologists from residency to academic and private practice. Two concerns are accuracy of interpretation from whole-slide images (WSI) and effect on workflow. Studies of considerably large series involving single-organ systems are lacking. Objective: To evaluate whether diagnosis from WSI on a digital microscope is inferior to diagnosis of glass slides from traditional microscopy (TM) in a large cohort of dermatopathology cases with attention on image resolution, specifically eosinophils in inflammatory cases and mitotic figures in melanomas, and to measure the workflow efficiency of WSI compared with TM...
October 11, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/29037427/-fibroepithelioma-of-pinkus-correlation-between-dermatopathology-and-dermoscopy
#17
P Huet, G Barnéon, B Cribier
No abstract text is available yet for this article.
October 13, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29034129/sebaceous-carcinoma-in-situ-as-a-concept-and-diagnostic-entity
#18
Miglena K Komforti, Masoud Asgari, Sheng Chen
Although carcinoma in situ has been accepted as a well-established concept and diagnostic category, for reasons unknown sebaceous carcinoma in situ has not been recognized yet in general pathology or dermatopathology. Such lesions have always been misinterpreted as either benign neoplasm or sebaceous carcinoma. In the present essay, we provide a convincing account supporting sebaceous carcinoma in situ as a valid concept and diagnostic entity via critical literature review and histopathological assessment and illustration...
July 2017: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/29023944/reconsidering-the-h-e-stain-as-the-gold-standard-in-assessing-the-depth-of-burn-wounds
#19
Arlene S Rosenberg
While histological examination is considered by most as the gold standard for burn depth assessment, it has no practical use in the clinical setting. It has, however, been used in the research setting, as a mean for evaluating emerging techniques of depth measurement. Due to the limitations of the H&E stain, other stains have also been explored, such as lactate dehydrogenase (LDH), as presented in this issue, in "Improving the Histologic Characterization of Burn Depth." As the determination of burn depth is not a typical subject in dermatopathology, a summary of selected techniques and the possible role for the LDH stain in future research, is described herein...
December 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29019822/endocervical-polyp-with-florid-epidermal-metaplasia-report-of-a-previously-undescribed-phenomenon-from-a-dermatopathologic-view-is-it-an-epidermal-inclusion-cyst-or-a-dermoid-cyst
#20
Tien Anh N Tran
No abstract text is available yet for this article.
November 2017: International Journal of Gynecological Pathology
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