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https://www.readbyqxmd.com/read/29775933/observing-hno-3-release-dependent-upon-metal-complexes-in-malonic-acid-nitrate-droplets
#1
Xu Shao, Feng-Min Wu, Hui Yang, Shu-Feng Pang, Yun-Hong Zhang
Although the dicarboxylic acid has been reported to react with nitrate for aged internally mixed aerosols in atmosphere, the quantitative nitrate depletion dependent upon composition in particles is still not well constrained. The chemical composition evolutions for malonic acid/sodium nitrate (MA/SN), malonic acid/magnesium nitrate (MA/MN) and malonic acid/calcium nitrate (MA/CN) particles with the organic to inorganic molar ratio (OIR) of 1:1 are investigated by vacuum Fourier transform infrared spectroscopy (FTIR)...
May 9, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29774606/nitrogen-doped-cop-electrocatalysts-for-coupled-hydrogen-evolution-and-sulfur-generation-with-low-energy-consumption
#2
Qingwen Zhou, Zihan Shen, Chao Zhu, Jiachen Li, Zhiyuan Ding, Peng Wang, Feng Pan, Zhiyong Zhang, Haixia Ma, Shuangyin Wang, Huigang Zhang
Hydrogen production is the key step for the future hydrogen economy. As a promising H2 production route, electrolysis of water suffers from high overpotentials and high energy consumption. This study proposes an N-doped CoP as the novel and effective electrocatalyst for hydrogen evolution reaction (HER) and constructs a coupled system for simultaneous hydrogen and sulfur production. Nitrogen doping lowers the d-band of CoP and weakens the H adsorption on the surface of CoP because of the strong electronegativity of nitrogen as compared to phosphorus...
May 17, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29768482/sequencing-of-complete-mitochondrial-genomes-confirms-synonymization-of-hyalomma-asiaticum-asiaticum-and-kozlovi-and-advances-phylogenetic-hypotheses-for-the-ixodidae
#3
Zhi-Qiang Liu, Yan-Feng Liu, Nuer Kuermanali, Deng-Feng Wang, Shi-Jun Chen, Hui-Ling Guo, Li Zhao, Jun-Wei Wang, Tao Han, Yuan-Zhi Wang, Jie Wang, Chen-Feng Shen, Zhuang-Zhi Zhang, Chuang-Fu Chen
Phylogeny of hard ticks (Ixodidae) remains unresolved. Mitochondrial genomes (mitogenomes) are increasingly used to resolve phylogenetic controversies, but remain unavailable for the entire large Hyalomma genus. Hyalomma asiaticum is a parasitic tick distributed throughout the Asia. As a result of great morphological variability, two subspecies have been recognised historically; until a morphological data-based synonymization was proposed. However, this hypothesis was never tested using molecular data. Therefore, objectives of this study were to: 1...
2018: PloS One
https://www.readbyqxmd.com/read/29768034/staphylococcus-aureus-induces-mucosal-type-2-immune-response-via-epithelial-cell-derived-cytokines
#4
Feng Lan, Nan Zhang, Gabriele Holtappels, Natalie De Ruyck, Olga Krysko, Koen Van Crombruggen, Harald Braun, Sebastian L Johnston, Nikos G Papadopoulos, Luo Zhang, Claus Bachert
RATIONALE: Chronic rhinosinusitis with nasal polyps is characterized by a T helper cell 2-skewed upper airway inflammation. Mucosal Staphylococcus aureus colonization is found in the majority of nasal polyps patients. Staphylococcus aureus is known to induce type 2 cytokine release via enterotoxins. OBJECTIVES: We investigated the impact of non-enterotoxin producing Staphylococcus aureus on type 2 cytokine release. METHODS: Thymic stromal lymphopoietin, interleukin-33 and type 2 cytokines were assessed in a human mucosal tissue model upon Staphylococcus aureus infection...
May 16, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29767655/proteomic-analysis-of-stachyose-contribution-to-the-growth-of-lactobacillus-acidophilus-cicc22162
#5
Xian-Feng Zhong, Yu-Bo Zhang, Gui-Dong Huang, Yong-Zhong Ouyang, Dong-Jiang Liao, Jia-Wei Peng, Wei-Zhi Huang
Stachyose is a functional oligosaccharide, acting as a potential prebiotic for colonic fermentation. To understand the mechanism of how stachyose promotes the growth of probiotic bacterium, we analyzed the differences of the proteome of Lactobacillus acidophilus grown on stachyose or glucose. By a combination of two-dimensional electrophoresis and mass spectrometry analysis, we observed 16 proteins differentially abundant under these two conditions and identified 9 protein spots. Six of these proteins were highly abundant when stachyose was used as the sole carbon source...
May 16, 2018: Food & Function
https://www.readbyqxmd.com/read/29767234/microrna-125a-5p-enhances-the-sensitivity-of-esophageal-squamous-cell-carcinoma-cells-to-cisplatin-by-suppressing-the-activation-of-the-stat3-signaling-pathway
#6
Yan Zhao, Ke Ma, Shujun Yang, Xiaosan Zhang, Feng Wang, Xiaqing Zhang, Hongtao Liu, Qingxia Fan
Increasing evidence has demonstrated that microRNAs (miRNAs or miRs) play a variety of roles in tumor development, progression and chemosensitivity in a wide range of tumors. In this study, we found that miR‑125a‑5p exhibited a low expression in esophageal squamous cell carcinoma (ESCC) tissues and cells, and that its low expression was associated with higher tumor staging and shorter a survival time of patients with ESCC. Moreover, miR‑125a‑5p overexpression contributed to the suppression of cell proliferation, cell cycle arrest, cell apoptosis and a decrease in cell migratory and invasive abilities, whereas the downregulation of miR‑125a‑5p promoted cell proliferation, accelerated cell cycle progression, suppressed apoptosis and enhanced the migratory and invasive abilities of ESCC EC1 and TE1 cells, which may be tightly associated with the epithelial‑mesenchymal transition (EMT) process in ESCC...
May 16, 2018: International Journal of Oncology
https://www.readbyqxmd.com/read/29766573/asymmetrical-ladder-type-donor-induced-polar-small-molecule-acceptor-to-promote-fill-factors-approaching-77-for-high-performance-nonfullerene-polymer-solar-cells
#7
Wei Gao, Miao Zhang, Tao Liu, Ruijie Ming, Qiaoshi An, Kailong Wu, Dongjun Xie, Zhenghui Luo, Cheng Zhong, Feng Liu, Fujun Zhang, He Yan, Chuluo Yang
In this work, an effectual strategy of constructing polar small molecule acceptors (SMAs) to promote fill factor (FF) of nonfullerene polymer solar cells (PSCs) is first reported. Three asymmetrical SMAs of IDT6CN, IDT6CN-Th, and IDT6CN-M, which own large dipole moments, are designed and synthesized. The PSCs based on three polar SMAs exhibit apparently higher FFs compared with their symmetrical analogues. The asymmetrical design strategy accompanied with side chain and end group engineering makes IDT6CN-Th- and IDT6CN-M-based nonfullerene PSCs achieve high power conversion efficiency with FFs approaching 77%...
May 15, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29765378/epithelial-c5ar1-signaling-enhances-uropathogenic-escherichia-coli-adhesion-to-human-renal-tubular-epithelial-cells
#8
Yun Song, Kun-Yi Wu, Weiju Wu, Zhao-Yang Duan, Ya-Feng Gao, Liang-Dong Zhang, Tie Chong, Malgorzata A Garstka, Wuding Zhou, Ke Li
Recent work in a murine model of ascending urinary tract infection has suggested that C5a/C5aR1 interactions play a pathogenic role in the development of renal infection through enhancement of bacterial adhesion/colonization to renal tubular epithelial cells (RTECs). In the present study, we extended these observations to human. We show that renal tubular epithelial C5aR1 signaling is involved in promoting uropathogenic Escherichia coli (UPEC) adhesion/invasion of host cells. Stimulation of primary cultures of RTEC with C5a resulted in significant increases in UPEC adhesion/invasion of the RTEC...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29763461/night-shift-work-exposure-profile-and-obesity-baseline-results-from-a-chinese-night-shift-worker-cohort
#9
Miaomiao Sun, Wenting Feng, Feng Wang, Liuzhuo Zhang, Zijun Wu, Zhimin Li, Bo Zhang, Yonghua He, Shaohua Xie, Mengjie Li, Joan P C Fok, Gary Tse, Martin C S Wong, Jin-Ling Tang, Samuel Y S Wong, Jelle Vlaanderen, Greg Evans, Roel Vermeulen, Lap Ah Tse
AIMS: This study aimed to evaluate the associations between types of night shift work and different indices of obesity using the baseline information from a prospective cohort study of night shift workers in China. METHODS: A total of 3,871 workers from five companies were recruited from the baseline survey. A structured self-administered questionnaire was employed to collect the participants' demographic information, lifetime working history, and lifestyle habits...
2018: PloS One
https://www.readbyqxmd.com/read/29760079/selection-and-environmental-adaptation-along-a-path-to-speciation-in-the-tibetan-frog-nanorana-parkeri
#10
Guo-Dong Wang, Bao-Lin Zhang, Wei-Wei Zhou, Yong-Xin Li, Jie-Qiong Jin, Yong Shao, He-Chuan Yang, Yan-Hu Liu, Fang Yan, Hong-Man Chen, Li Jin, Feng Gao, Yaoguang Zhang, Haipeng Li, Bingyu Mao, Robert W Murphy, David B Wake, Ya-Ping Zhang, Jing Che
Tibetan frogs, Nanorana parkeri , are differentiated genetically but not morphologically along geographical and elevational gradients in a challenging environment, presenting a unique opportunity to investigate processes leading to speciation. Analyses of whole genomes of 63 frogs reveal population structuring and historical demography, characterized by highly restricted gene flow in a narrow geographic zone lying between matrilines West (W) and East (E). A population found only along a single tributary of the Yalu Zangbu River has the mitogenome only of E, whereas nuclear genes of W comprise 89-95% of the nuclear genome...
May 14, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29757351/m10-a-novel-derivative-of-myricetin-prevents-ulcerative-colitis-and-colorectal-tumor-through-attenuating-robust-endoplasmic-reticulum-stress
#11
Feng Wang, Zhi-Yu Song, Xian-Jun Qu, Feng Li, Liang Zhang, Wen-Bao Li, Shu-Xiang Cui
Chronic gut inflammation disposes to an increased risk of colitis-associated cancer (CAC). Chemoprevention is an attractive complementary strategy. We aimed to evaluate the chemopreventive effects of M10, a novel derivative of Myricetin, in the murine azoxymethane (AOM)/dextran sodium sulfate (DSS) model. Oral administration of M10 at 50-100 mg/kg once a day for consecutive 12 weeks significantly prevented ulcerative colitis and colorectal tumor. Pathological analysis of intestines showed that M10 reduced the degree of chronic inflammation and prevented the progression of colorectal tumorigenesis...
May 11, 2018: Carcinogenesis
https://www.readbyqxmd.com/read/29756036/tuning-peptide-self-assembly-by-an-in-tether-chiral-center
#12
Kuan Hu, Yixiang Jiang, Wei Xiong, Hu Li, Pei-Yu Zhang, Feng Yin, Qianling Zhang, Hao Geng, Fan Jiang, Zhou Li, Xinwei Wang, Zigang Li
The self-assembly of peptides into ordered nanostructures is important for understanding both peptide molecular interactions and nanotechnological applications. However, because of the complexity and various self-assembling pathways of peptide molecules, design of self-assembling helical peptides with high controllability and tunability is challenging. We report a new self-assembling mode that uses in-tether chiral center-induced helical peptides as a platform for tunable peptide self-assembly with good controllability...
May 2018: Science Advances
https://www.readbyqxmd.com/read/29755519/simulated-cholinergic-reinnervation-of-%C3%AE-ins-1-cells-antidiabetic-utility-of-heterotypic-pseudoislets-containing-%C3%AE-cell-and-cholinergic-cell
#13
Ao Jiao, Feng Li, Chengshuo Zhang, Wu Lv, Baomin Chen, Jialin Zhang
Cholinergic neurons can functionally support pancreatic islets in controlling blood sugar levels. However, in islet transplantation, the level of cholinergic reinnervation is significantly lower compared to orthotopic pancreatic islets. This abnormal reinnervation affects the survival and function of islet grafts. In this study, the cholinergic reinnervation of beta cells was simulated by 2D and 3D coculture of INS-1 and NG108-15 cells. In 2D culture conditions, 20 mM glucose induced a 1.24-fold increase ( p < 0...
2018: International Journal of Endocrinology
https://www.readbyqxmd.com/read/29751724/-textual-research-on-origin-and-genuine-of-lilii-bulbus
#14
Chang-Hua Wang, Shu Shu, Fu-Jun Yin, Ji-Feng Zhao, Zhi-Wei Zhang, Xiang Liu, Zhi-Lai Zhan
Lilii Bulbus, which comes from many medicinal plants,is a frequently-used traditional Chinese medicine,the records in previous herbal literatures of it's origin and quality were inconstant. To trace back it's sources, we conducted a systematical study on it's origin and quality by textual research and investigation in this paper,The result showed that the origins of Lilii Bulbus are mainly source from white-flowers, red-yellow-flowers and red-flowers of Lilium, L. brownii var. viridulum, which were believed authentic or good quality in all previous herbal literatures,and L...
April 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29748000/deletion-of-the-c6orf120-gene-with-unknown-function-ameliorates-autoimmune-hepatitis-induced-by-concanavalin-a
#15
Man-Ka Zhang, Hui-Min Ma, Jian Zhang, Xin-Cheng Song, Xiao-Hui Ye, Yu-Feng Li, Yi-Fan Zhang, Ling-Ling He, Hong-Shan Wei, Xin Li
The present study was conducted to characterize the C6orf120 gene, by using C6orf120 gene-deleted rats (C6orf120- / - ), to determine its role in the development and severity of autoimmune hepatitis induced by concanavalin A (Con A), as well as the underlying mechanisms. We found that following Con A injection, C6orf120- / - rats were less susceptible to developing autoimmune hepatitis with low levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) post challenge. Additionally, C6orf120 deficiency increased the frequency of cluster of differentiation (CD)4+ CD25+ Forkhead box P3+ regulatory T cells (Tregs) among intrahepatic lymphocytes, splenocytes, peripheral blood mononuclear cells, and CD4+ T in vitro...
May 2, 2018: Cellular Immunology
https://www.readbyqxmd.com/read/29745509/-research-on-malignant-arrhythmia-detection-algorithm-using-neural-network-optimized-by-genetic-algorithm
#16
Ming Yu, Feng Chen, Guang Zhang, Liangzhe Li, Chunchen Wang, Ningbo Zhan, Biao Gu, Jing Wei, Taihu Wu
Detection and classification of malignant arrhythmia are key tasks of automated external defibrillators. In this paper, 21 metrics extracted from existing algorithms were studied by retrospective analysis. Based on these metrics, a back propagation neural network optimized by genetic algorithm was constructed. A total of 1,343 electrocardiogram samples were included in the analysis. The results of the experiments indicated that this network had a good performance in classification of sinus rhythm, ventricular fibrillation, ventricular tachycardia and asystole...
June 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29745181/-analysis-and-comprehensive-evaluation-on-cold-resistance-of-six-varieties-of-michelia
#17
Rui Xue Li, Xiao Ling Jin, Xi Jun Hu, Yi Xia Chai, Meng Ying Cai, Feng Luo, Fang Jing Zhang
Taking six varieties of Michelia as test materials, their responses under cold situation in the field were investigated and the semilethal low temperatures were calculated by fitting Logistic equation. The nine structure indexes of leaf tissue were observed by paraffin section, and a comprehensive evaluation on cold resistance of different varieties was given according to subordinate function value analysis. The results showed that the relative electrical conductivity of six varieties of Michelia was significantly positively correlated with the semilethal low temperature (LT50 ) of 3 h 0-25 ℃ treatment...
May 18, 2017: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://www.readbyqxmd.com/read/29739373/acute-and-chronic-toxicity-of-a-polyherbal-preparation-jueyin-granules
#18
Yu Chen, Dong-Jie Guo, Hui Deng, Min-Feng Wu, Ya-Nan Zhang, Su Li, Rong Xu, Jie Chen, Xing-Xiu Jin, Bin Li, Qi Xu, Fu-Lun Li
BACKGROUND: The potential toxicity of Chinese herbal medicine has attracted more attention in recent years. Jueyin granules (JYG), a polyherbal formula, have been proven to be an effective agent for treating psoriasis in both animal models and clinical research. However, little is known about the possible acute and chronic toxicity of JYG. The objective of this study was to investigate the safety of JYG in ICR mice and Wistar rats. METHODS: To examine the acute toxicity of JYG, ICR mice were randomly divided into an experimental group and a control group, each comprising 20 mice (10 male and 10 female)...
May 8, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29737745/-discussion-on-the-micro-plastic-operative-treatment-of-nasal-septum-deviation-combined-with-crooked-nose
#19
Yi Feng Tong, Nan Nan Zhang, Xin Ran Zhang, Qing Feng Zhang
OBJECTIVES: To explore the micro-plastic operative treatment of deviated nose combined with nasal septum deviation. METHODS: We designed the incision at the caudal side of the nasal septum. The three-line reduction method for correcting nasal septum deviation was performed. The connection of the caudal nasal septum and the anterior nasal spine was reposited. The micro-plastic surgery with fixed suture was used to correct the deviated nose. RESULTS: After the surgery, the nasal septum deviation was corrected, whose nasal function and symptoms improved without nasal adhesion, nasal septum perforation or other complications...
March 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29735452/-characteristics-of-collateral-circulation-in-adult-moyamoya-disease-based-on-modified-suzuki-staging
#20
Qing-Shun Zhao, Gang Wang, Hao-Jiang Xiao, Wen-Feng Feng, Guo-Zhong Zhang, Ming-Zhou Li, Yong-Hong Liao, Yun-Yu Wen, Song-Tao Qi
OBJECTIVE: To investigate the characteristics of collateral circulation in adult moyamoya disease (MMD). METHODS: The clinical data were collected from all adult patients with MMD undergoing digital subtractive angiography (DSA) in our department from 2006 to 2016. Based on the imaging findings, the patients were divided into ischemia group and bleeding group. A double-blind analysis was conducted of the CT or magnetic resonance imaging findings and the severity of the disease was graded using the modified Suzuki score (mSS)...
April 20, 2018: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
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