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"Feng Zhang"

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https://www.readbyqxmd.com/read/28934778/the-effect-of-early-use-of-supplemental-therapy-on-preventing-postherpetic-neuralgia-a-systematic-review-and-meta-analysis
#1
Xiu-Fang Xing, Zhen-Feng Zhou, Feng-Jiang Zhang, Min Yan
BACKGROUND: Postherpetic neuralgia (PHN) is the most common and refractory complication of herpes zoster (HZ). Aggressive treatment of acute pain in HZ has the potential to prevent the development of PHN, but the preventive efficacy of supplemental therapy commonly used in clinical practice is controversial. OBJECTIVES: Our aim is to examine the efficacy of supplemental therapy in preventing PHN. STUDY DESIGN: A meta-analysis. SETTING: All of the selected studies are randomized controlled trials (RCTs)...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28929661/-evaluation-of-effect-of-supplementing-qi-and-activating-blood-decoction-based-on-combined-model-of-intestinal-out-cardiac-muscle-cells-and-discussion-of-its-mechanism
#2
Ya Geng, Hong-Jun Yang, Yue-Xiang Ma, Jing-Jing Zhang, Yi Zhang, De-Feng Li, Fang-Bo Zhang, Hai-Yu Xu
This research firstly establishes the oxidative damage model of H9c2 induced by H2O2 and screens the concentration range of intestines absorption liquid of Qi benefiting and blood circulation activating formula which possess external myocardium protection function. Then, the thesis chooses 4 dosages to conduct experiments:examining the protection function of intestines absorption liquid of Qi benefiting and blood circulation activating formula on H9c2 to provide reference for clinical prevention and curing of relative heart diseases of oxidative stress injury; as well as examining the H9c2 cardiac muscle cell vigour, cellular morphology, SOD, MDA and other indexes to primarily evaluate and discuss the functional mechanism of intestines absorption liquid of Qi benefiting and blood circulation activating formula...
October 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28927462/generation-of-special-autosomal-dominant-polycystic-kidney-disease-ipscs-with-the-capability-of-functional-kidney-like-cell-differentiation
#3
Jiahui Huang, Shumin Zhou, Xin Niu, Bin Hu, Qing Li, Feng Zhang, Xue Zhang, Xiujuan Cai, Yuanlei Lou, Fen Liu, Chenming Xu, Yang Wang
BACKGROUND: Human induced pluripotent stem cells (iPSCs) have been verified as a powerful cell model for the study of pathogenesis in hereditary disease. Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations of PKD or non-PKD genes. The pathogenesis of ADPKD remains unexplored because of the lack of a true human cell model. METHODS: Six ADPKD patients and four healthy individuals were recruited as donors of somatic cells from a Chinese ADPKD family without mutations of the PKD genes but carrying SAMSN1 gene deletion...
September 19, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28925544/metaproteomics-of-marine-viral-concentrates-reveals-key-viral-populations-and-abundant-periplasmic-proteins-in-the-oligotrophic-deep-chlorophyll-maximum-of-the-south-china-sea
#4
Zhang-Xian Xie, Feng Chen, Shu-Feng Zhang, Ming-Hua Wang, Hao Zhang, Ling-Fen Kong, Min-Han Dai, Hua-Sheng Hong, Lin Lin, Da-Zhi Wang
Viral concentrates (VCs), containing bio-informative DNA and proteins, have been used to study viral diversity, viral metagenomics and virus-host interactions in natural ecosystems. Besides viruses, VCs also contain many non-cellular biological components including diverse functional proteins. Here, we used a shotgun proteomic approach to characterize the proteins of VCs collected from the oligotrophic deep chlorophyll maximum (DCM) of the South China Sea. Proteins of viruses infecting picophytoplankton, i...
September 19, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28921929/tumor-suppressive-mir-145-co-repressed-by-tcf4-%C3%AE-catenin-and-prc2-complexes-forms-double-negative-regulation-loops-with-its-negative-regulators-in-colorectal-cancer
#5
Wei Wang, Xin Xiao, Xu Chen, Yi Huo, Wen-Jin Xi, Zhi-Feng Lin, Dan Zhang, Yu-Fang Li, Fan Yang, Wei-Hong Wen, An-Gang Yang, Tao Wang
The frequently dysregulated Wnt/β-catenin signaling in different malignancies, by activation of its own or orchestration with other co-factors, regulates various oncogenic or tumor-suppressive genes. Among these genes, miRNAs, which are negative posttranscriptional regulators, are also embedded in the Wnt signaling network. Different from the Wnt-induced oncogenic miRNAs, the specific mechanism underlying the Wnt-repressed tumor-suppressive miRNAs is much less understood. In the present study, firstly by analyzing a ChIP-seq dataset against TCF4, the core transcription factor for initiation of Wnt signaling in colorectal cancer (CRC) cells, we screened out several tumor-suppressive miRNAs potentially regulated by Wnt signaling...
September 16, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28919752/zinc-oxide-nanoparticles-induce-apoptosis-and-autophagy-in-human-ovarian-cancer-cells
#6
Ding-Ping Bai, Xi-Feng Zhang, Guo-Liang Zhang, Yi-Fan Huang, Sangiliyandi Gurunathan
BACKGROUND: Zinc oxide nanoparticles (ZnO NPs) are frequently used in industrial products such as paint, surface coating, and cosmetics, and recently, they have been explored in biologic and biomedical applications. Therefore, this study was undertaken to investigate the effect of ZnO NPs on cytotoxicity, apoptosis, and autophagy in human ovarian cancer cells (SKOV3). METHODS: ZnO NPs with a crystalline size of 20 nm were characterized with various analytical techniques, including ultraviolet-visible spectroscopy, X-ray diffraction, transmission electron microscopy, Fourier transform infrared spectroscopy, and atomic force microscopy...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28915664/morusin-inhibits-cell-proliferation-and-tumor-growth-by-down-regulating-c-myc-in-human-gastric-cancer
#7
Feng Wang, Dunke Zhang, Jingxin Mao, Xiao-Xue Ke, Rui Zhang, Chao Yin, Ning Gao, Hongjuan Cui
Morusin is a pure extract from the root bark of Morus australis (Moraceae). In recent years, morusin has been reported to exhibit anti-tumor biological activity in some types of human cancers through different mechanisms. Here, we attempted to investigate the inhibitory effect and mechanism of morusin on gastric cancer. Morusin markedly inhibited gastric cancer cell proliferation by down-regulating CDKs and Cyclins, such as CDK2, CDK4, Cyclin D1 and Cyclin E1. Additionally, morusin suppressed tumor growth in vitro and in vivo...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28914895/experimental-generation-of-discrete-ultraviolet-wavelength-by-cascaded-intermodal-four-wave-mixing-in-a-multimode-photonic-crystal-fiber
#8
Jinhui Yuan, Zhe Kang, Feng Li, Xianting Zhang, Chao Mei, Guiyao Zhou, Xinzhu Sang, Qiang Wu, Binbin Yan, Xian Zhou, Kangping Zhong, Kuiru Wang, Chongxiu Yu, Gerald Farrell, Chao Lu, Hwa Yaw Tam, P K A Wai
In this Letter, we demonstrate experimentally for the first time, to the best of our knowledge, discrete ultraviolet (UV) wavelength generation by cascaded intermodal FWM when femtosecond pump pulses at 800 nm are launched into the deeply normal dispersion region of the fundamental guided mode of a multimode photonic crystal fiber (MPCF). For pump pulses at average input powers of Pav=450, 550, and 650 mW, the first anti-Stokes waves are generated at the visible wavelength of 538.1 nm through intermodal phase matching between the fundamental and second-order guided mode of the MPCF...
September 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28910728/hygroscopicity-of-internally-mixed-particles-composed-of-nh4-2so4-and-citric-acid-under-pulsed-rh-change
#9
Xiao-Min Shi, Feng-Min Wu, Bo Jing, Na Wang, Lin-Lin Xu, Shu-Feng Pang, Yun-Hong Zhang
In this research, we applied a pulsed RH controlling system and a rapid scan vacuum FTIR spectrometer (PRHCS-RSVFTIR) to investigate hygroscopicity of internally mixed (NH4)2SO4(AS)/citric acid (CA) particles. The water content and efflorescence ratio of AS in the particles and ambient relative humidity (RH) as a function of time were obtained with a subsecond time resolution. The hygroscopic behavior of AS aerosols in two different RH control processes (equilibrium and RH pulsed processes) showed that AS droplets crystallize with RH ranging from 42% to 26...
September 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/28910331/reproducibility-of-frequency-dependent-low-frequency-fluctuations-in-reaction-time-over-time-and-across-tasks
#10
Zan-Zan Liu, Hui-Jie Qu, Zhuo-Ling Tian, Meng-Jian Han, Yi Fan, Lie-Zhong Ge, Yu-Feng Zang, Hang Zhang
OBJECTIVE: Increased levels of reaction time variability (RTV) are characteristics of sustained attention deficits. The clinical significance of RTV has been widely recognized. However, the reliability of RTV measurements has not been widely studied. The present study aimed to assess the test-retest reliability of RTV conventional measurements, e.g., the standard deviation (SD), the coefficient of variation (CV), and a new measurement called the amplitude of low frequency fluctuation (ALFF) of RT...
2017: PloS One
https://www.readbyqxmd.com/read/28910074/highly-luminescent-phase-stable-cspbi3-perovskite-quantum-dots-achieving-near-100-absolute-photoluminescence-quantum-yield
#11
Feng Liu, Yaohong Zhang, Chao Ding, Syuusuke Kobayashi, Takuya Izuishi, Naoki Nakazawa, Taro Toyoda, Takeshi Ohta, Shuzi Hayase, Takashi Minemoto, Kenji Yoshino, Songyuan Dai, Qing Shen
Perovskite quantum dots (QDs) as a new type of colloidal nanocrystals have gained significant attention for both fundamental research and commercial applications owing to their appealing optoelectronic properties and excellent chemical processability. For their wide range of potential applications, synthesizing colloidal QDs with high crystal quality is of crucial importance. However, like most common QD systems such as CdSe and PbS, those reported perovskite QDs still suffer from a certain density of trapping defects, giving rise to detrimental non-radiative recombination centers and thus quenching luminescence...
September 14, 2017: ACS Nano
https://www.readbyqxmd.com/read/28903432/genetic-variation-and-forensic-characteristic-analysis-of-25-strs-of-a-novel-fluorescence-co-amplification-system-in-chinese-southern-shaanxi-han-population
#12
Yao-Shun Liu, Jian-Gang Chen, Ting Mei, Yu-Xin Guo, Hao-Tian Meng, Jian-Fei Li, Yuan-Yuan Wei, Xiao-Ye Jin, Bo-Feng Zhu, Li-Ping Zhang
We analyzed the genetic polymorphisms of 15 autosomal and 10 Y-chromosomal STR loci in 214 individuals of Han population from Southern Shaanxi of China and studied the genetic relationships between Southern Shaanxi Han and other populations. We observed a total of 150 alleles at 15 autosomal STR loci with the corresponding allelic frequencies ranging from 0.0023 to 0.5210, and the combined power of discrimination and exclusion for the 15 autosomal STR loci were 0.99999999999999998866 and 0.999998491, respectively...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28903339/ing5-knockdown-enhances-migration-and-invasion-of-lung-cancer-cells-by-inducing-emt-via-egfr-pi3k-akt-and-il-6-stat3-signaling-pathways
#13
Xin-Li Liu, Xu-Tao Zhang, Jin Meng, Hong-Fei Zhang, Yong Zhao, Chen Li, Yang Sun, Qi-Bing Mei, Feng Zhang, Tao Zhang
ING5 belongs to the Inhibitor of Growth (ING) candidate tumor suppressor family, whose functions have been involved in the regulation of chromatin remodeling, cell cycle progression, proliferation and apoptosis. Our previous study has shown that ING5 overexpression inhibits lung cancer aggressiveness via suppressing epithelial to mesenchymal transition (EMT). However, the mechanisms remain largely unknown. In the current study, by Phospho-Kinase array and western blot, we have defined significantly upregulated EGFR/PI3K/Akt and IL-6/STAT3 oncogenic signaling pathways in ING5 knockdown A549 cells, which could be downregulated by ING5 overexpression...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28901400/taurine-alleviates-lipopolysaccharide%C3%A2-induced-liver-injury-by-anti%C3%A2-inflammation-and-antioxidants-in-rats
#14
Yueyan Liu, Feng Li, Li Zhang, Jianfeng Wu, Yanmei Wang, Hong Yu
The aim of the present study was to investigate the protective effect of taurine on lipopolysaccharide (LPS)‑induced liver injury and its mechanisms. Male rats were randomly divided into three groups: Normal saline, LPS model and taurine treatment. Experimental animals were treated with saline or taurine (dissolved in saline, 200 mg/kg/day) via intravenous injection. After 2 h, saline or LPS (0.5 mg/kg) was administrated via intraperitoneal injection. Markers of liver injury, pro‑inflammatory cytokines and superoxide dismutase (SOD) activity were determined in plasma...
August 31, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28901161/polyphenolic-compounds-from-malus-hupehensis-and-their-free-radical-scavenging-effects
#15
Qingwen Hu, Ying-Ying Chen, Qi-Yang Jiao, Afsar Khan, Jimiao Shan, Gui-Dong Cao, Feng Li, Chao Zhang, Hong-Xiang Lou
One new 4-chromanone glycoside, 5-O-β-d-glucopyranoside-4-chromanone (1), together with 21 known polyphenols, was isolated from the leaves of Malus hupehensis. Their structures were elucidated on the basis of extensive spectroscopic methods including NMR (1D and 2D), mass (ESIMS and HRESIMS), IR, and by comparison with the data reported in the literature. Some of the isolated compounds were screened for antioxidant activity. Compounds 18 and 14 exhibited significant antioxidant activities with SC50 values 2...
September 13, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28898086/theoretical-discovery-of-superconducting-two-dimensional-metal-organic-framework
#16
Feng Liu, Xiaoming Zhang, Yinong Zhou, Bin Cui, Mingwen Zhao
Superconductivity is a fascinating quantum phenomenon characterized by zero electrical resistance and the Meissner effect. To date, several distinct families of superconductors (SCs) have been discovered. These include three-dimensional (3D) bulk SCs in both inorganic and organic materials as well as two-dimensional (2D) thin film SCs but only in inorganic materials. Here we predict superconductivity in 2D and 3D organic metal-organic frameworks by using first-principles calculations. We show that the highly conductive and recently synthesized Cu-benzenehexathial (BHT) is a Bardeen-Cooper-Schrieffer SC...
September 12, 2017: Nano Letters
https://www.readbyqxmd.com/read/28891305/antioxidant-phenolic-acids-from-the-leaves-of-armeniaca-sibirica
#17
Ya-Nan Wu, Wei Wang, Guo-Dong Yao, Xue-Feng Jiang, Yan Zhang, Shao-Jiang Song
Phytochemical investigation of the leaves of Armeniaca sibirica (L.) Lam. led to the isolation of two new phenolic acids (1-2), together with eight known compounds (3-10) from the ethanol extracts of this plant. Structures of these compounds were elucidated through detailed spectroscopic analyses, using 1D-NMR and 2D-NMR in combination with HR-EI-MS techniques. All the compounds were evaluated for their antioxidant capabilities in vitro using 2, 2'-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS), 1, 1'-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assays, and ferric-reducing antioxidant power (FRAP) methods...
September 11, 2017: Journal of Asian Natural Products Research
https://www.readbyqxmd.com/read/28888065/synthesizing-value-added-products-from-methane-by-a-new-methylomonas
#18
Wei Guo, Demao Li, Ronglin He, Minghuo Wu, Wuxi Chen, Feng Gao, Zhidan Zhang, Yonghong Yao, Liang Yu, Shulin Chen
AIMS: Methane and methanol are potential carbon sources of industrial microorganisms in addition to crop-derived bio-carbon sources. Methanotrophs that can utilize these simple, stable and large amounts chemicals are expected to be developed into "cell factories" for the production of specific chemicals. In this study,a methanotroph that can synthesize lycopene, C30 carotenoid and exopolysaccharides with relative better performances from C1 substrates was isolated, and its performances were evaluated...
September 9, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28887977/magnetic-electrospun-short-nanofibers-wrapped-graphene-oxide-as-a-promising-biomaterials-for-guiding-cellular-behavior
#19
Zhang-Qi Feng, Chuanmei Shi, Bin Zhao, Ting Wang
Magnetic particles show extremely wide application prospects in the biomedical field, particularly in the success of cellular manipulation, drug delivery systems, magnetic hyperthermia and NRI contrast enhancement. Graphene oxide with functional groups has a promising biological effect. In this work, we develop magnetic short-fibers wrapped graphene oxide for guiding cellular behavior with the aid of high-speed shear of nanofibers fabricated through electrospinning technique. The diameter and the length of short-fibers are about 300nm and 80μm, respectively...
December 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28886421/a-method-to-describe-inelastic-gamma-field-distribution-in-neutron-gamma-density-logging
#20
Feng Zhang, Quanying Zhang, Juntao Liu, Xinguang Wang, He Wu, Wenbao Jia, Yongzhou Ti, Fei Qiu, Xiaoyang Zhang
Pulsed neutron gamma density logging (NGD) is of great significance for radioprotection and density measurement in LWD, however, the current methods have difficulty in quantitative calculation and single factor analysis for the inelastic gamma field distribution. In order to clarify the NGD mechanism, a new method is developed to describe the inelastic gamma field distribution. Based on the fast-neutron scattering and gamma attenuation, the inelastic gamma field distribution is characterized by the inelastic scattering cross section, fast-neutron scattering free path, formation density and other parameters...
August 21, 2017: Applied Radiation and Isotopes
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