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Aging & pregnancy

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https://www.readbyqxmd.com/read/28351027/re-thinking-elective-single-embryo-transfer-increased-risk-of-monochorionic-twinning-a-systematic-review
#1
Margaret Dziadosz, Mark I Evans
BACKGROUND/OBJECTIVES: Multiple pregnancies have tripled in the United States over the past 3 decades. Attributed to increasing maternal age at delivery but more so assisted reproductive technological advances, an effort has been made to decrease twinning through elective single embryo transfer. We sought to review and evaluate risks of monochorionic twinning as a predictable consequence of increasing utilization of elective single embryo transfer on perinatal outcomes. Primary outcomes included twinning rates, fetal anomalies, growth, preterm birth, and mortality...
March 29, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28350879/maternal-psychological-responses-during-pregnancy-after-ultrasonographic-detection-of-structural-fetal-anomalies-a-prospective-longitudinal-observational-study
#2
Anne Kaasen, Anne Helbig, Ulrik F Malt, Tormod Næs, Hans Skari, Guttorm Haugen
In this longitudinal prospective observational study performed at a tertiary perinatal referral centre, we aimed to assess maternal distress in pregnancy in women with ultrasound findings of fetal anomaly and compare this with distress in pregnant women with normal ultrasound findings. Pregnant women with a structural fetal anomaly (n = 48) and normal ultrasound (n = 105) were included. We administered self-report questionnaires (General Health Questionnaire-28, Impact of Event Scale-22 [IES], and Edinburgh Postnatal Depression Scale) a few days following ultrasound detection of a fetal anomaly or a normal ultrasound (T1), 3 weeks post-ultrasound (T2), and at 30 (T3) and 36 weeks gestation (T4)...
2017: PloS One
https://www.readbyqxmd.com/read/28350836/perceived-psychosocial-stress-and-gestational-weight-gain-among-women-with-gestational-diabetes
#3
Ai Kubo, Assiamira Ferrara, Susan D Brown, Samantha F Ehrlich, Ai-Lin Tsai, Charles P Quesenberry, Yvonne Crites, Monique M Hedderson
Growing evidence links perceived stress-a potentially modifiable psychosocial risk factor-with health behaviors and obesity. Yet little is known about the relationship between stress during pregnancy and gestational weight gain, particularly among women with pregnancy complications. We conducted a cross-sectional analysis to examine associations between psychosocial stress during pregnancy and gestational weight gain among women with gestational diabetes. We used baseline data from the Gestational Diabetes's Effects on Moms (GEM) study: 1,353 women with gestational diabetes who delivered a term singleton within Kaiser Permanente Northern California were included...
2017: PloS One
https://www.readbyqxmd.com/read/28350823/cluster-analysis-to-estimate-the-risk-of-preeclampsia-in-the-high-risk-prediction-and-prevention-of-preeclampsia-and-intrauterine-growth-restriction-predo-study
#4
Pia M Villa, Pekka Marttinen, Jussi Gillberg, A Inkeri Lokki, Kerttu Majander, Maija-Riitta Ordén, Pekka Taipale, Anukatriina Pesonen, Katri Räikkönen, Esa Hämäläinen, Eero Kajantie, Hannele Laivuori
OBJECTIVES: Preeclampsia is divided into early-onset (delivery before 34 weeks of gestation) and late-onset (delivery at or after 34 weeks) subtypes, which may rise from different etiopathogenic backgrounds. Early-onset disease is associated with placental dysfunction. Late-onset disease develops predominantly due to metabolic disturbances, obesity, diabetes, lipid dysfunction, and inflammation, which affect endothelial function. Our aim was to use cluster analysis to investigate clinical factors predicting the onset and severity of preeclampsia in a cohort of women with known clinical risk factors...
2017: PloS One
https://www.readbyqxmd.com/read/28350728/an-unusual-case-of-right-upper-quadrant-pain-in-a-pregnant-woman
#5
Veena Modayil, Mathew Nelson, Brendon Stankard
Uterine fibroids occur in up to 30% of women of reproductive age and can cause complications during pregnancy that can harm mother and fetus, such as prematurity and increased risk of miscarriage. This article describes a pregnant woman whose abdominal pain was diagnosed as degenerating uterine fibroids.
April 2017: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/28346240/combined-oral-medroxyprogesterone-levonorgestrel-intrauterine-system-treatment-for-women-with-grade-2-stage-ia-endometrial-cancer
#6
Ji Young Hwang, Da Hee Kim, Hyo Sook Bae, Mi-La Kim, Yong Wook Jung, Bo Seong Yun, Seok Ju Seong, Eunah Shin, Mi Kyoung Kim
OBJECTIVE: The aim of this study was to evaluate the oncologic and pregnancy outcomes of combined oral medroxyprogesterone acetate (MPA)/levonorgestrel-intrauterine system (LNG-IUS) treatment in young women with grade 2-differentiated stage IA endometrial adenocarcinoma who wish to preserve fertility. METHODS: We retrospectively reviewed the medical records of patients with grade 2 stage IA endometrial adenocarcinoma who had received fertility-sparing treatment at CHA Gangnam Medical Center between 2011 and 2015...
March 24, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28345979/assessment-and-treatment-options-for-patients-with-constipation
#7
Alison Bardsley
Constipation is a common complaint for people of all ages, with prevalence increasing with age and during pregnancy. Women are more likely to be affected than men. Severity of constipation varies from person to person; most people experience short periods of constipation during their lives, including possibly after surgery, while others have constipation as a chronic long-term condition that can significantly affect their quality of life. There are a number of factors that can contribute to developing constipation including diets low in fibre, changes in lifestyle, side effects of certain medications and low fluid intake...
March 23, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28345680/personal-and-occupational-risk-factors-for-carpal-tunnel-syndrome-in-meat-processing-industry-workers-in-northern-italy
#8
Matteo Riccò, Carlo Signorelli
BACKGROUND: Carpal tunnel syndrome (CTS) is a musculoskeletal condition that often impairs the fitness to work. Our aim is to retrospectively evaluate the association between physical exposures in meat processing industry in Northern Italy and the CTS, taking into account non-occupational factors. MATERIAL AND METHODS: A cross-sectional study was performed to include 434 workers (236 males, 198 females, 37.0±10.6 years old, working age: 12.6±10.8 years) from meat processing industries...
March 24, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28345432/utero-placental-perfusion-doppler-indices-in-growth-restricted-fetuses-effect-of-sildenafil-citrate
#9
Mohamed Adel El-Sayed, Said Abdel-Aty Saleh, Mohammad Ahmed Maher, Asmaa Mohamed Khidre
OBJECTIVE: To assess efficacy and tolerability of sildenafil citrate on utero-placental blood flow and fetal growth in pregnancies complicated by fetal growth restriction (FGR). METHODS: From March 2015, a randomized controlled trial of 54 patients at 24 weeks or more complicated by FGR and abnormal Doppler indices were randomly allocated 1:1 into an intervention arm (receive sildenafil citrate, 50 mg) or a control arm (receive placebo). The primary outcomes were changes occurred in the Doppler parameters 2 h following drug administration...
March 27, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28344961/recurrence-factors-and-reproductive-outcomes-of-laparoscopic-myomectomy-and-minilaparotomic-myomectomy-for-uterine-leiomyomas
#10
Dong Gi Shin, Heon Jong Yoo, Yeon Ah Lee, In Sun Kwon, Ki Hwan Lee
OBJECTIVE: The aim of this study was to determine recurrence factors and reproductive outcomes of laparoscopic myomectomy (LM) and minilaparotomic myomectomy (MM) for treating uterine leiomyomas. METHODS: Between 2007 and 2013, 160 patients underwent myomectomy, including 122 who underwent LM and 38 who underwent MM. Patients were followed up for recurrence based on pelvic ultrasound exams. Only patients who were followed up for a minimum of two years were selected for this retrospective study...
March 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28344956/maternal-serum-placental-growth-factor-and-pregnancy-associated-plasma-protein-a-measured-in-the-first-trimester-as-parameters-of-subsequent-pre-eclampsia-and-small-for-gestational-age-infants-a-prospective-observational-study
#11
Kyung Uk Sung, Jeong A Roh, Kyung Jin Eoh, Eui Hyeok Kim
OBJECTIVE: To examine the first-trimester maternal serum placental growth factor (PlGF) and pregnancy-associated plasma protein A (PAPP-A) levels in pregnancies associated with pre-eclampsia (PE) or small-for-gestational-age (SGA) infants, and determine the predictive accuracy of PlGF and of PAPP-A for either PE or SGA infants. METHODS: This prospective, observational study included 175 pregnant women, and of these women, due to participant withdrawal or loss to follow-up, delivery data were collected from the medical records of 155 women, including 4 who had twin pregnancies...
March 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28343943/insomnia-treatment-preferences-during-pregnancy
#12
Ivan D Sedov, Sherryl H Goodman, Lianne M Tomfohr-Madsen
OBJECTIVE: To determine pregnant women's preferences for the treatment of insomnia: cognitive behavioral therapy (CBT-I), pharmacotherapy, or acupuncture. DESIGN: A cross-sectional survey of pregnant women. SETTING: We recruited participants in person at a low-risk maternity clinic and a pregnancy and infant trade show and invited them to complete an online questionnaire. PARTICIPANTS: The sample (N = 187) was primarily White (70%), married or common-law married (96%), and on average 31 years of age; the mean gestational age was 28 weeks...
March 24, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28343772/report-of-the-who-technical-consultation-on-the-effect-of-maternal-influenza-and-influenza-vaccination-on-the-developing-fetus-montreal-canada-september-30-october-1-2015
#13
Deshayne B Fell, Zulfiqar A Bhutta, Jennifer A Hutcheon, Ruth A Karron, Marian Knight, Michael S Kramer, Arnold S Monto, Geeta K Swamy, Justin R Ortiz, David A Savitz
In 2012, the World Health Organization (WHO) released a position paper on influenza vaccination recommending that pregnant women have the highest priority for seasonal vaccination in countries where the initiation or expansion of influenza immunization programs is under consideration. Although the primary goal of the WHO recommendation is to prevent influenza illness in pregnant women, the potential benefits of maternal immunization in protecting young infants are also recognized. The extent to which maternal influenza vaccination may prevent adverse birth outcomes such as preterm birth or small-for-gestational-age birth, however, is unclear as available studies are in disagreement...
March 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28343733/low-risk-papillary-microcarcinoma-of-the-thyroid-a-review-of-active-surveillance-trials
#14
REVIEW
Y Ito, A Miyauchi, H Oda
Papillary microcarcinoma (PMC) of the thyroid is defined as papillary thyroid carcinoma (PTC) measuring ≤1 cm. Many autopsy studies on subjects who died of non-thyroidal diseases reported latent small thyroid carcinoma in up to 5.2% of the subjects. A mass screening study for thyroid cancer in Japanese adult women detected small thyroid cancer in 3.5% of the examinees. This incidence was close to the incidence of latent thyroid cancer and more than 1000 times the prevalence of clinical thyroid cancer in Japanese women reported at that time...
March 16, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28343562/prenatal-exposure-to-diurnal-temperature-variation-and-early-childhood-pneumonia
#15
Ji Zeng, Chan Lu, Qihong Deng
BACKGROUND: Childhood pneumonia is one of the leading single causes of mortality and morbidity in children worldwide, but its etiology still remains unclear. OBJECTIVE: We investigate the association between childhood pneumonia and exposure to diurnal temperature variation (DTV) in different timing windows. METHODS: We conducted a prospective cohort study of 2,598 children aged 3-6 years in Changsha, China. The lifetime prevalence of pneumonia was assessed by a questionnaire administered by the parents...
April 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/28343414/zika-virus-and-pregnant-women-a-psychological-approach
#16
Juliana Fernandes Filgueiras Meireles, Clara Mockdece Neves, Fabiane Frota da Rocha Morgado, Maria Elisa Caputo Ferreira
Zika virus presents risk of physical harm to pregnant women, but the fear of infection is also affecting women around the world. There is a gap in the research on Zika virus in the areas involving the impact on the psychosocial well-being of pregnant women. Therefore, this study is aimed at the investigation of the psychosocial adjustment of pregnant women to the risks of Zika virus infection during pregnancy. We investigated 14 pregnant women who were classified in three different groups: six in the first trimester, five in the second trimester and three in the third trimester, aged from 28 to 40 years (33...
March 27, 2017: Psychology & Health
https://www.readbyqxmd.com/read/28343179/nulliparous-teenagers-and-preterm-birth-in-california
#17
Jonathan A Mayo, Bat Zion Shachar, David K Stevenson, Gary M Shaw
BACKGROUND: Young maternal age is one of the numerous risk factors for delivery before 37 weeks of gestation, yet the mechanisms are unclear. The purpose of the current study was to investigate the association between teenagers and the risk of preterm birth (PTB) in a large and recent cohort study. METHODS: We conducted a population-based retrospective cohort study using 2007-2011 California birth certificate records linked with hospital discharge indices and United States census data for nulliparous 13-20 year olds who gave birth to singletons...
March 27, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28342962/intellectual-evaluation-of-children-exposed-to-phthalate-tainted-products-after-the-2011-taiwan-phthalate-episode
#18
Po-Chin Huang, Chih-Hsin Tsai, Chu-Chih Chen, Ming-Tsang Wu, Mei-Lien Chen, Shu-Li Wang, Bai-Hsiun Chen, Ching-Chang Lee, Jouni J K Jaakkola, Wen-Chiu Wu, Min-Kung Chen, Chao A Hsiung, Rapit Group
INTRODUCTION: Phthalate exposure may reduce intellectual development in young children. In 2011, numerous Taiwanese children had been reported to have consumed phthalate-tainted products. We investigated the effects of phthalate exposure on the intellectual development of these children after the 2011 Taiwan di-2-ethylhexyl phthalate (DEHP) episode. METHODS: We recruited 204 children, aged 3-12 y, from 3 hospitals in Taiwan between 2012 and 2013. First-morning urine samples were collected for analyzing 5 phthalate metabolites...
March 23, 2017: Environmental Research
https://www.readbyqxmd.com/read/28342949/use-of-thiopurines-during-conception-and-pregnancy-not-associated-with-adverse-pregancy-outcomes-or-health-of-infants-at-1-year-in-a-prospective-study
#19
Shannon L Kanis, Alison de Lima-Karagiannis, Nanne K H de Boer, C Janneke van der Woude
BACKGROUND & AIMS: Most data on the safety of thiopurine therapy for inflammatory bowel disease (IBD) during pregnancy come from retrospective studies, making it difficult to adjust for confounding factors. We performed a prospective cohort study to determine whether thiopurine use affects pregnancy outcomes or health outcomes of children. METHODS: We performed a prospective study of all women who visited the IBD preconception outpatient clinic at our tertiary health center in The Netherlands from December 2008 through May 2016...
March 22, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28342658/educational-needs-of-adolescents-with-congenital-heart-disease-impact-of-a-transition-intervention-programme
#20
Magalie Ladouceur, Johanna Calderon, Maladon Traore, Radhia Cheurfi, Christine Pagnon, Diala Khraiche, Fanny Bajolle, Damien Bonnet
BACKGROUND: Adolescents and young adults with congenital heart disease (CHD) have complex health needs and require lifelong follow-up. Interventions to facilitate the paediatric-to-adult healthcare transition are recommended, but outcomes remain largely under-investigated. AIMS: To identify the educational needs and the impact of a transition intervention on knowledge and self-management skills in adolescents and young adults with CHD. METHODS: From September 2014 to May 2015, 115 adolescents and young adults with CHD (mean age 17±2 years; 47 girls) were consecutively enrolled...
March 22, 2017: Archives of Cardiovascular Diseases
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