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Aging ailments

Man Hung, Jerry Bounsanga, Maren W Voss, Charles L Saltzman
AIM: To establish minimum clinically important difference (MCID) for measurements in an orthopaedic patient population with joint disorders. METHODS: Adult patients aged 18 years and older seeking care for joint conditions at an orthopaedic clinic took the Patient-Reported Outcomes Measurement Information System Physical Function (PROMIS® PF) computerized adaptive test (CAT), hip disability and osteoarthritis outcome score for joint reconstruction (HOOS JR), and the knee injury and osteoarthritis outcome score for joint reconstruction (KOOS JR) from February 2014 to April 2017...
March 18, 2018: World Journal of Orthopedics
Toye Gabriel Olajide, Kayode Shuaib Aremu, Olaide T Esan, Adepeju Oluwatona Dosunmu, Mustapha Muhammad Raji
Background: Self-medication is a common habit in our country; Nigeria, especially among patients with otorhinolaryngological disorders. Medication when taken wrongly may bring dire consequences to the individual, such as masking developing diseases and may cause many other undesirable effects. The aim of this study was to determine the prevalence and to analyze topical ear drop self-medication practices among respondents attending the Ear, Nose, and Throat Clinic of Federal Teaching Hospital Ido Ekiti, Nigeria...
April 2018: Annals of African Medicine
Imtiaz Hussain, Ondrej Mach, Nasir A Hamid, Zaid S Bhatti, Deborah D Moore, M Steven Oberste, Shahid Khan, Hasan Khan, William C Weldon, Roland W Sutter, Zulfiqar A Bhutta, Sajid B Soofi
BACKGROUND: Afghanistan is one of the remaining wild-poliovirus (WPV) endemic countries. We conducted a seroprevalence survey of anti-poliovirus antibodies in Kandahar Province. METHODS: Children in two age groups (6-11 months and 36-48 months) visiting Mirwais hospital in Kandahar for minor ailments unrelated to polio were enrolled. After obtaining informed consent, we collected venous blood and conducted neutralization assay to detect poliovirus neutralizing antibodies...
March 3, 2018: Vaccine
R Shyama Prasad Rao, Ning Zhang, Dong Xu, Ian Max Møller
Motivation: Oxidative stress and protein damage have been associated with over 200 human ailments including cancer, stroke, neuro-degenerative diseases, and aging (Fedorova et al., 2014. Mass Spectrom. Rev., 33, 79-97). Protein carbonylation, a chemically diverse oxidative post-translational modification (PTM), is widely considered as the biomarker for oxidative stress and protein damage. Despite their importance and extensive studies, no database/resource on carbonylated proteins/sites exists...
March 2, 2018: Bioinformatics
Mariola Janiszewska, Teresa Kulik, Dorota Żołnierczuk-Kieliszek, Barłomiej Drop, Ewelina Firlej, Ilona Gajewska
Introduction: Contemporary people do not follow the civilisation development in every life domain, their lifestyle is not always healthy. Self-efficacy is the factor that plays an important role in undertaking actions towards struggling with the disease. The aim of the study: The aim of the study was to determine the relationship between the general self-efficacy level and health behaviours as well as chosen sociodemographic features in women over the age of 45 years who have undergone osteoporosis treatment...
September 2017: Przeglad Menopauzalny, Menopause Review
Sunil Rajpal, Abhishek Kumar, William Joe
With the ongoing demographic and epidemiological transition, cancer is emerging as a major public health concern in India. This paper uses nationally representative household survey to examine the overall prevalence and economic burden of cancer in India. The age-standardized prevalence of cancer is estimated to be 97 per 100,000 persons with greater prevalence in urban areas. The evidence suggests that cancer prevalence is highest among the elderly and also among females in the reproductive age groups. Cancer displays a significant socioeconomic gradient even after adjusting for age-sex specifics and clustering in a multilevel regression framework...
2018: PloS One
Neelam Rashid, Rodrigue Castro Gbedomon, Mushtaq Ahmad, Valère Kolawolé Salako, Muhammad Zafar, Khafsa Malik
BACKGROUND: Traditional knowledge about the use of medicinal plants for herbal drinks (HDs) is not well documented in the Azad Kashmir region despite their widespread use. This study highlights the taxonomic diversity and traditional knowledge on medicinal plants used for HDs while examining the diversity of diseases treated with HDs in the study area. METHODS: Individual discussions were conducted with 255 informants (84 women and 171 men). Data gathered included (i) informant age and gender, (ii) HD species and respective plant parts used, (iii) health disorders treated, and (iv) mode of preparation and utilizations...
February 21, 2018: Journal of Ethnobiology and Ethnomedicine
Sivakumar Dharmasivam, Ramya Selvaraj, Subitha Lakshminarayanan, Sitanshu Sekhar Kar, S Ganesh Kumar
Background: Client satisfaction on quality of medication services perceived by the patients is an important measure of the health services and needs to be addressed to improve the utilization of primary health-care services. Methods: This is a descriptive study on quality of medication services perceived by the patients attending a rural health center in Puducherry. The data were collected with pretested semi-structured questionnaire. The study population consisted of 365 patients...
July 2017: Journal of Family Medicine and Primary Care
Maho Omori, Deborah Dempsey
Adopting Kleinman's and Lock's ideas that there are cultural variations in understandings of health care and the medicalisation of ageing bodies, this study compares and contrasts older adults' use of anti-ageing medicine in two cultural settings. Based on 42 interviews conducted in Australia and Japan with adults aged 60 and over, findings revealed distinct pathways to initiating anti-ageing medicine use between the two cohorts which reflect different attitudes to the medicalisation of ageing in the two settings...
February 6, 2018: Sociology of Health & Illness
Jun Young Choi, Heri Babu, Francis Ngimwhichi Joseph, Stephanie Stephanie, Jin Soo Suh
BACKGROUND: Maasai tribe members walk long distances daily either barefoot or wearing traditional shoes made from recycled car tires, without any foot ailments. To figure out the characteristic of their feet, we designed a radiographic comparative study of middle-aged partially shod Maasai women's feet and regularly shod Maasai and Korean women's feet. METHODS: Weight bearing radiographs of bilateral foot and ankle joints from 20 healthy middle-aged bush-living partially shod (PS) Maasai women were obtained...
April 4, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Minkyung Han, Sohee Park, Jong Heon Park, Seung-Sik Hwang, Inah Kim
OBJECTIVES: The work of public officers involves repeated and long-term exposure to heavy workloads, high job strain and workplace violence, all of which negatively impact physical and mental health. This study aimed to evaluate and compare the incidences of diseases among different categories of public officers in Korea, in order to further understand the health risks associated with these occupations. DESIGN: A cohort study using the National Health Insurance data...
January 31, 2018: BMJ Open
Andrzej Marcinkiewicz, Michał Plewka, Wojciech Hanke, Paweł Kałużny, Marta Wiszniewska, Agnieszka Lipińska-Ojrzanowska, Jolanta Walusiak-Skorupa
BACKGROUND: Due to high prevalence, insufficient recognition and ineffectual treatment, hypertension (HT) still remains a major medical and socio-economic problem. There is a real necessity to develop effective prophylaxis for cardiovascular disorders (CVD), based on strategies which support compliance during long-term therapy. The Polish scheme of occupational health services (OHS) with mandatory periodical employee check-ups creates a unique opportunity for effective HT prophylaxis...
January 19, 2018: Kardiologia Polska
Veronika Cakova, Frederic Bonte, Annelise Lobstein
Dendrobium represents one of the most important orchid genera, ornamentally and medicinally. Dendrobiums are sympodial epiphytic plants, which is a name they are worthy of, the name coming from Greek origin: "dendros", tree, and "bios", life. Dendrobium species have been used for a thousand years as first-rate herbs in traditional Chinese medicine (TCM). They are source of tonic, astringent, analgesic, antipyretic, and anti-inflammatory substances, and have been traditionally used as medicinal herbs in the treatment of a variety of disorders, such as, nourishing the stomach, enhancing production of body fluids or nourishing Yin...
December 2017: Aging and Disease
César Navarro-Albarracín, Serge Poiraudeau, Noelia Chico-Matallana, Jesús Vergara-Martín, William Martin, Adelaida María Castro-Sánchez, Guillermo A Matarán-Peñarrocha
BACKGROUND AND OBJETIVE: To validate the Spanish version of the Exercise Therapy Burden Questionnaire (ETBQ) for the assessment of barriers associated to doing physical therapy for the treatment of chronic ailments. PATIENTES AND METHODS: A sample of 177 patients, 55.93% men and 44.07% women, with an average age of 51.03±14.91 was recruited. The reliability of the questionnaire was tested with Cronbach's alpha coefficient, and the validity of the instrument was assessed through the divergent validation process and factor analysis...
January 8, 2018: Medicina Clínica
Daniel Pitz Jacobsen, Morten Birkeland Nielsen, Ståle Einarsen, Johannes Gjerstad
Objectives Long-term exposure to systematic negative acts at work, usually labeled workplace bullying, is a prevalent problem at many workplaces. The adverse effects of such exposure may range from psychological symptoms, such as depression and anxiety to somatic ailments like cardiovascular disease and musculoskeletal complaints. In this study, we examined the relationships among exposure to negative acts, genetic variability in the 5-HTT gene SLC6A4 and pain. Methods The study was based on a nationally representative survey of 987 Norwegian employees drawn from the Norwegian Central Employee Register by Statistics Norway...
January 9, 2018: Scandinavian Journal of Work, Environment & Health
Priyanga Ranasinghe, Ranil Jayawardena, Shehani Pigera, Wasundara Sevwandi Wathurapatha, Hasitha Dhananjaya Weeratunga, G A Sirimal Premakumara, Prasad Katulanda, Godwin Roger Constantine, Priyadarshani Galappaththy
BACKGROUND: Cinnamon is considered as a treatment for many ailments in native medicine. Evidence suggests that Cinnamomum zeylanicum (CZ) has anti-microbial, anti-parasitic, anti-oxidant, blood glucose lowering properties and beneficial cardiovascular effects. The present study aims to evaluate Pharmacodynamic properties and safety of CZ in healthy adults using a Phase I Clinical Trial. METHODS: This phase I clinical trial was conducted at the Department of Pharmacology, Faculty of Medicine, University of Colombo, Sri Lanka...
December 28, 2017: BMC Complementary and Alternative Medicine
Khulood Othman Alyahya
BACKGROUND: Ongoing studies in the Middle East, particularly in the Arabian Gulf countries, have reported extremely low levels of serum vitamin D across age and gender. In Kuwait, vitamin D deficiency is prevalent in adolescent girls and in adult women. A number of risk factors have been reported, among which gender, age, and obesity are a few. Because adequate vitamin D status is necessary to promote bone mineral accrual in childhood, and because low vitamin D levels have been associated with a wide range of health problems, there is concern that growing children with low vitamin D may be at higher risk for developing diseases...
December 22, 2017: BMC Pediatrics
Negar Firouzabadi, Anna Nazariat, Kamiar Zomorrodian
PURPOSE: Autism, a neuropsychiatric illness, is a complex ailment of mainly indefinite cause. Although precise pathophysiological mechanism is unclear but the role of genetics is undeniable therefore pharmacogenetics may assist to a better management of symptoms. Risperidone is widely used in autism. Considering the significance of dopaminergic system in psychological and neurological diseases and its association with autism, the hypothesis that genetic variant of dopamine receptor (DRD3), Ser9Gly (rs6280), may influence treatment of autism may be assumed...
2017: Journal of Pharmacy & Pharmaceutical Sciences: a Publication of the Canadian Society for Pharmaceutical Sciences
Pawan Krishan, Onkar Bedi, Monika Rani
The inappropriate dietary habits lead to the onset of age-related pathologies which include diabetes and cardiovascular ailments. Dietary restriction and nutritional therapy play an important role in the prevention of these chronic ailments. Preclinical research provides a basis for the therapeutic exploration of new dietary interventions for the clinical trials to potentiate the scientific management of diabetes and its related complications which further help in translating these nutritional improvements from bench to bedside...
December 16, 2017: Naunyn-Schmiedeberg's Archives of Pharmacology
Subrata Naskar, Praveen Kumar Jakati
As research, has progressed through ages, we have been able to uncover the true nature of nicotine addiction. Humankind is now aware of the various ailments that it brings with it. As the slogan for a smokeless world for a better world has been raised, a new practice called "vaping" has come to the forefront. The use of electronic cigarettes (EC) has been on the rise recently. Claims have been made over its role for nicotine deaddiction as well as reducing harmful use for chronic nicotine abusers...
September 2017: Indian Journal of Psychological Medicine
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