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https://www.readbyqxmd.com/read/27900276/foreign-body-in-duodenum-mimicking-a-duplication-cyst-on-imaging
#1
Aditya Pratap Singh, Vinay Mathur, Ramesh Tanger, Arun Gupta, Ayush Kumar
Paediatric age group is most vulnerable for the accidental foreign body (FB) ingestion which may go unnoticed. These patients present with symptoms or complications as a result of FB and may mimic other conditions on various investigations. We describe a 9-month old infant who ingested crystal gel ball and presented with vomiting for a month. On radiological imaging it was interpreted as duplication cyst of the duodenum. At operation, crystal gel ball was retrieved. Our case vindicates importance of keeping various possibilities in mind as differential diagnoses during evaluation and management of surgical ailments such as the duplication cyst of duodenum...
November 2016: APSP Journal of Case Reports
https://www.readbyqxmd.com/read/27859564/excess-mortality-in-the-myelodysplastic-syndromes
#2
Meritxell Nomdedeu, Arturo Pereira, Fernando Ramos, David Valcárcel, Dolors Costa, Montserrat Arnan, Xavier Calvo, Helena Pomares, Elisa Luño, María Díaz-Campelo, Rosa Collado, Raquel de Paz, José-Francisco Falantes, Carme Pedro, Josefa Marco, Itziar Oirtzabal, Joaquín Sánchez-García, Mar Tormo, María-Teresa Cedena, Benet Nomdedeu, Guillermo Sanz
Myelodysplastic syndromes (MDS) are the commonest hematologic malignancies in the elderly. Since many patients with MDS actually die from age-related ailments, the very disease burden of MDS remains largely unknown. This registry-based study was aimed at investigating the excess mortality attributable to MDS. We analyzed 7,408 adult patients diagnosed with primary MDS from 1980 to 2014. Excess mortality was estimated by comparing the patients' survival with that expected in the matched general population. Median age of patients was 74 years, 58% were males, and 65% belonged to the lower risk categories of the Revised International Prognostic Scoring System (IPSS-R)...
November 14, 2016: American Journal of Hematology
https://www.readbyqxmd.com/read/27817745/cell-free-circulating-epigenomic-signatures-non-invasive-biomarker-for-cardiovascular-and-other-age-related-chronic-diseases
#3
Arpit Bhargava, Naveen Kumar Khare, Neha Bunkar, Koel Chaudhury, Kailash Chand Pandey, Subodh Kumar Jain, Pradyumna Kumar Mishra
The burden of cardio-vascular and other age-related non-communicable diseases are rapidly increasing worldwide. Majority of these chronic ailments are curable, if diagnosed at early stages. Candidate biomarkers of early detection are therefore essential for identification of high-risk individuals, prompt and accurate disease diagnosis, and to monitor therapeutic response. The functional significance of circulating nucleic acids that recapitulate specific disease profiles is now well established. But subtle changes in DNA sequence may not solely reflect the differentiation of gene expression patterns observed in diverse set of diseases as epigenetic phenomena play a larger role in aetiology and patho-physiology...
October 27, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27800662/awareness-and-prevalence-of-diabetes-hypertension-and-hypercholesterolemia-in-malaysia
#4
Steven T Yen, Andrew K G Tan, Mustapha I Feisul
BACKGROUND: Policy interventions of cardiovascular diseases require individual awareness of ailments. Such awareness is also key to changes by individuals in lifestyle and dietary habits. This study investigates the association of socio-demographic and health-lifestyle factors with awareness and prevalence of three ailments: diabetes, hypertension, and hypercholesterolemia. METHODS: Data are obtained from the Malaysia Non-Communicable Disease Surveillance-1. Logistic regressions are estimated and odds ratios of exposure variables calculated...
November 1, 2016: Journal of Diabetes
https://www.readbyqxmd.com/read/27796758/circular-rnas-the-emerging-class-of-non-coding-rnas-and-their-potential-role-in-human-neurodegenerative-diseases
#5
REVIEW
Lalit Kumar, Shamsuzzama, Rizwanul Haque, Tanvi Baghel, Aamir Nazir
The exciting world of research with RNAs has to its credit some breakthrough findings that led to newer insights on multiple problems including that of human diseases. After the advent of siRNA, microRNA, and lncRNA, exciting novel molecules called circular RNAs (circRNAs) have been recently described. circRNAs are a class of non-coding RNAs, which are produced by scrambling of exons at the time of splicing. They are primarily produced in the brain region and are naturally present inside the cell. The best known ones so far include a particular type of circRNA namely "circular RNA sponge for miR-7" (ciRS-7 and CDR1as) which is the inhibitor of miR-7 microRNA-known to regulate various diseases like, cancer, neurodegenerative diseases, diabetes, and atherosclerosis...
October 29, 2016: Molecular Neurobiology
https://www.readbyqxmd.com/read/27785163/patients-perception-of-pharmaceutical-services-available-in-a-community-pharmacy-among-patients-living-in-a-rural-area-of-the-united-kingdom
#6
Piotr Merks, Damian ŚWieczkowski, Miłosz J Jaguszewski
OBJECTIVE: Patients' opinion about prevalence of pharmaceutical services available in a community pharmacy among patients living in a rural area of the United Kingdom. The secondary objective was to identify appropriate action(s) to enhance patients' awareness of pharmaceutical services in rural areas. METHODS: A self-administered, anonymous questionnaire was distributed to patients visiting a community pharmacy in Eye, Suffolk, United Kingdom between July and August, 2015...
July 2016: Pharmacy Practice
https://www.readbyqxmd.com/read/27780131/plant-derived-cardiac-glycosides-role-in-heart-ailments-and-cancer-management
#7
REVIEW
Seema Patel
Cardiac glycosides, the cardiotonic steroids such as digitalis have been in use as heart ailment remedy since ages. They manipulate the renin-angiotensin axis to improve cardiac output. However; their safety and efficacy have come under scrutiny in recent times, as poisoning and accidental mortalities have been observed. In order to better understand and exploit them as cardiac ionotropes, studies are being pursued using different cardiac glycosides such as digitoxin, digoxin, ouabain, oleandrin etc. Several cardiac glycosides as peruvoside have shown promise in cancer control, especially ovary cancer and leukemia...
October 22, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27697138/acceptance-and-commitment-group-therapy-act-g-for-health-anxiety
#8
Trine Eilenberg
Health anxiety is prevalent (5-9%) in all healthcare settings and in the general population, may have an early onset, and a poor prognosis is seen in severe cases if untreated. Research shows that health anxiety is rarely diagnosed though it causes great suffering for the individual and constitutes a substantial socio-economic burden. Studies have shown that individual cognitive behavioural therapy can relieve health anxiety, but these studies are affected by methodological problems, among others, struggling with patients declining participation, high dropout rates, and some patients not responding to the treatment...
October 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/27695669/environmental-determinants-of-aplastic-anemia-in-pakistan-a-case-control-study
#9
Mehwesh Taj, Tayyaba Shah, Syeda Kanwal Aslam, Sidra Zaheer, Faryal Nawab, Sumaira Shaheen, Kashif Shafique, Tahir Sultan Shamsi
AIM: Aplastic anemia (AA) affects the Asian population two to three fold more than people in other regions. Besides the host genetics and socioeconomic status, several other environmental exposures have been linked with an AA etiology. We aimed to examine the association of various environmental exposures with AA occurrence among Pakistani individuals. SUBJECTS AND METHODS: A case-control study was conducted in Karachi, Pakistan, where cases (diagnosed AA patients) were selected from the National Institute of Blood Disease and Bone Marrow Transplantation (NIBD), while for each case, a single control (who was free of AA and visited the outpatient department of the same hospital for the treatment of minor ailments) was selected matched by age and sex...
2016: Zeitschrift Für Gesundheitswissenschaften, Journal of Public Health
https://www.readbyqxmd.com/read/27689598/ergonomic-footwear-for-sri-lankan-primary-schoolchildren-a-review-of-the-literature
#10
I S Hettigama, H K G Punchihewa, N K Heenkenda
BACKGROUND: Foot ailments are common among schoolchildren, some of which may be attributed to wearing ill-fitting footwear. As schoolchildren often participate in athletic activity, they are doubly vulnerable to foot ailments, and are particularly vulnerable to conditions such as hallux valgus, Achilles tendonitis, athlete's foot, corns and calluses. Thus, there is an acute need for the design and manufacture of ergonomic footwear for this target group. While research on appropriate footwear for children has been carried out in relation to child populations in other societies, research on the circumstances of Sri Lankan schoolchildren is lacking...
October 17, 2016: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/27686062/do-circadian-rhythms-draw-the-patterns-of-sustained-mental-vigor-and-ailment
#11
Ashish Sharma, Rohit Goyal
Preclinical Research Circadian rhythms are fundamental processes in all cells that coordinate a variety of cellular functions related to a specific time of the day. Disruption of circadian rhythms markedly impacts homeostasis. In this Commentary, we present data that disruption of circadian rhythm may lead to the pathogenesis of neurodegenerative states. In this context, we further argue that there is an urgent need of developing new generations of compounds, chronobiotics, to modulate the molecular substrates of circadian timing system...
September 30, 2016: Drug Development Research
https://www.readbyqxmd.com/read/27651081/sleep-quality-of-call-handlers-employed-in-international-call-centers-in-national-capital-region-of-delhi-india
#12
J D Raja, S K Bhasin
BACKGROUND: Call center sector in India is a relatively new and fast growing industry driving employment and growth in modern India today. Most international call centers in National Capital Region (NCR) of Delhi operate at odd work hours corresponding to a time suitable fortheir international customers. The sleep quality of call handlers employed in these call centers is in jeopardy owing to their altered sleep schedule. OBJECTIVE: To assess the sleep quality and determine its independent predictors among call handlers employed in international call centers in NCR of Delhi...
October 2016: International Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27625486/air-medical-transportation-in-india-our-experience
#13
Himanshu Khurana, Yatin Mehta, Sunil Dubey
BACKGROUND AND AIMS: Long distance air travel for medical needs is on the increase worldwide. The condition of some patients necessitates specially modified aircraft, and monitoring and interventions during transport by trained medical personnel. This article presents our experience in domestic and international interhospital air medical transportation from January 2010 to January 2014. MATERIAL AND METHODS: Hospital records of all air medical transportation undertaken to the institute during the period were analyzed for demographics, primary etiology, and events during transport...
July 2016: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/27621516/intelligence-quotient-and-concept-of-deha-m%C3%A4-nasa-prak%C3%A1-ti-in-ayurveda
#14
Vijaykumar Nandvadekar, Sandeep V Binorkar
BACKGROUND: Ayurveda has classified humans according to Deha-Mānasa prakṛti. It has given equal emphasis to both physical and psychological status of the individual. Constitution or configuration is an individual's peculiar set up of body and mind. It is also of importance in etiopathogenesis, prognosis and treatment procedures of various ailments. It is said that nature has its relative roles in causing individual and group differences in their respective cognitive abilities. AIM: The present study was designed to validate and assess the Intelligence Quotient of individuals of different Prakṛtis...
April 2016: Ancient Science of Life
https://www.readbyqxmd.com/read/27605951/ear-related-problems-among-children-attending-the-paediatric-and-otorhinolaryngology-out-patients-clinics-of-the-university-of-nigeria-teaching-hospital-enugu
#15
G C Ilechukwu, Cga Ilechukwu, B C Ezeanolue, I J Okoroafor, N C Ojinnaka, A C Ubesie, G O Emechebe, J Eze
BACKGROUND: Ear related diseases are commonly seen in clinics worldwide especially among children. They are associated with significant morbidity and frequent hospital visits. Limited data exists regarding the burden of ear disease among Nigerian children. OBJECTIVE: To determine the prevalence of ear-related problems among children presenting at the Paediatric and Otorhinolaryngology clinics of the University of Nigeria Teaching Hospital, Enugu. MATERIALS AND METHODS: This was a cross-sectional study conducted at the Paediatric and Otorhinolaryngology Clinics of the University of Nigeria Teaching Hospital Enugu...
June 2016: African Health Sciences
https://www.readbyqxmd.com/read/27582609/medical-and-surgical-treatment-modalities-for-lower-urinary-tract-symptoms-in-the-male-patient-secondary-to-benign-prostatic-hyperplasia-a-review
#16
REVIEW
Matthew Ryan Macey, Mathew C Raynor
Benign prostatic hyperplasia (BPH) with lower urinary tract symptoms (LUTS) is one of the most common ailments affecting aging men. Symptoms typically associated with BPH include weak stream, hesitancy, urgency, frequency, and nocturia. More serious complications of BPH include urinary retention, gross hematuria, bladder calculi, recurrent urinary tract infection, obstructive uropathy, and renal failure. Evaluation of BPH includes a detailed history, objective assessment of urinary symptoms with validated questionnaires, and measurement of bladder function parameters, including uroflowmetry and postvoid residual...
September 2016: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/27576513/health-related-quality-of-life-of-older-asian-patients-with-multimorbidity-in-primary-care-in-a-developed-nation
#17
Joanne Hui Min Quah, Pei Wang, Roderica Rui Ge Ng, Nan Luo, Ngiap Chuan Tan
AIM: Older adults are susceptible to two or more chronic ailments or multimorbidity. The present study aimed to establish the relationship between multimorbidity and health-related quality of life (HRQoL) amongst Asian elderly patients in primary care in a developed nation. It also assessed how functional disability and chronic musculoskeletal pain are associated with HRQoL. METHODS: A cross-sectional study was carried out in a Singapore public primary care clinic...
August 31, 2016: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/27563437/initiating-therapeutic-relaxation-in-britain-a-twentieth-century-strategy-for-health-and-wellbeing
#18
Ayesha Nathoo
In 1972, a British charity, Relaxation for Living, was established "to promote the teaching of physical relaxation, to combat stress, strain, anxiety and the tension of modern life, and to reduce fatigue". This article explores the origins and development of "physical relaxation" techniques and ideologies, starting in the interwar period, and the development of practical, therapeutic, social and cultural frameworks necessary for such an organization to come into being in 1970s Britain. It traces how relaxation was reconstituted as a scientifically-based skill that could be learnt and taught, imbued with therapeutic value for combating and preventing specific physical ailments and enhancing individual health and wellbeing...
July 19, 2016: Palgrave Communications
https://www.readbyqxmd.com/read/27518117/-incidence-of-knee-injuries-numbers-for-outpatient-and-inpatient-care-in-germany
#19
O Schneider, H-P Scharf, T Stein, S Knapstein, C Hermann, J Flechtenmacher
BACKGROUND: Musculoskeletal illnesses and injuries are among the most common ailments in the Federal Republic of Germany. In 2008 they generated costs of nearly 29 billion euros. Figures about their incidence and prevalence are necessary for a demand-oriented planning of future patient-centred care. METHOD: Pseudonymised data of 3.8 million people insured by AOK Baden-Württemberg between 2008 and 2013 were evaluated. The diagnoses were assigned to nine injury groups...
August 12, 2016: Der Orthopäde
https://www.readbyqxmd.com/read/27495844/epidemiologic-and-demographic-attributes-of-primary-spondylodiscitis-in-a-middle-eastern-population-sample
#20
K Venugopal Menon, Tamer Malak Moawad Sorour
BACKGROUND: The prevalence and characteristics of spontaneous spondylodiscitis in the Middle East is unknown. There seems to be an emerging dominance of pyogenic infections over Tuberculosis and Brucellosis. METHODS: Retrospective observational study based on electronic case records of 4 years from a tertiary reference facility in Oman. Case records, microbiology reports, blood reports, imaging studies, histopathology and surgical reports of all spinal infection cases were studied...
August 2, 2016: World Neurosurgery
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