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https://www.readbyqxmd.com/read/29775210/the-effect-of-simulated-space-radiation-on-the-n-glycosylation-of-human-immunoglobulin-g1
#1
Mate Szarka, Szabolcs Szilasi, Boglarka Donczo, Daniel Sarkozy, Istvan Rajta, Andras Guttman
On a roundtrip to Mars, astronauts are expectedly exposed to an approximate amount of radiation that exceeds the lifetime limits on Earth. This elevated radiation dose is mainly due to Galactic Cosmic Rays (GCR) and Solar Particle Events (SPE). Specific patterns of the N-glycosylation of human immunoglobulins have already been associated with various ailments such as autoimmune diseases, malignant transformation, chronic inflammation and ageing. The focus of our work was to investigate the effect of low-energy proton irradiation on the IgG N-glycosylation profile with the goal if disease associated changes could be detected during space travel and not altered by space radiation...
May 18, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29769017/a-cross-sectional-investigation-of-the-health-needs-of-asylum-seekers-in-a-refugee-clinic-in-germany
#2
Laura F Goodman, Guy W Jensen, Joseph M Galante, Diana L Farmer, Stephanie Taché
BACKGROUND: Over one million asylum seekers were registered in Germany in 2016, most from Syria and Afghanistan. The Refugee Convention guarantees access to healthcare, however delivery mechanisms remain heterogeneous. There is an urgent need for more data describing the health conditions of asylum seekers to guide best practices for healthcare delivery. In this study, we describe the state of health of asylum seekers presenting to a multi-specialty primary care refugee clinic. METHODS: Demographic and medical diagnosis data were extracted from the electronic medical records of patients seen at the ambulatory refugee clinic in Dresden, Germany between 15 September 2015 and 31 December 2016...
May 16, 2018: BMC Family Practice
https://www.readbyqxmd.com/read/29743917/concurrent-use-of-herbal-and-orthodox-medicines-among-residents-of-tamale-northern-ghana-who-patronize-hospitals-and-herbal-clinics
#3
Evans Paul Kwame Ameade, Mohammed Ibrahim, Halimatu-Sadia Ibrahim, Rabiatu Hamisu Habib, Stephen Yao Gbedema
Despite the development of more researched and formulated orthodox medicines, herbal medicines continue to be well patronized for persons across the world with some patrons concurrently using both forms, oblivious of the unwanted effects that may occur. Using a multistage sampling procedure, a semistructured questionnaire was used to collect data in April 2016 from 240 informants from three selected hospitals and three herbal clinics in Tamale, a city in northern Ghana. Using Statistical Package for the Social Sciences, binary logistic regression was used to determine sociodemographic predictors of concurrent use of herbal and orthodox medicines...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29732221/predicting-long-term-renal-damage-in-children-with-vesicoureteral-reflux-under-conservative-initial-management-205-cases-in-a-tertiary-referral-center
#4
Natalia Alvarez, Reyes Delgado Alvira, Yurema Gonzalez Ruiz, Rafael Fernandez Atuan, Alexander Siles Hinojosa, Miguel Angel Rihuete Heras, Marisa Justa Roldan, Jesus Gracia Romero
Introduction: Vesicoureteral reflux (VUR) is one of the most common ailments in children. Evidence-based guidelines recommend conservative treatment in children with VUR, followed by endoscopic surgery in those with breakthrough febrile urinary tract infections (UTIs). Despite this fact, the management of VUR is still controversial. Our objective is to evaluate the conservative strategy in children with primary VUR in terms of renal function and scarring, and identify factors associated with poor prognosis in those children...
2018: Central European Journal of Urology
https://www.readbyqxmd.com/read/29701283/therapeutic-effect-of-northern-labrador-tea-extracts-for-acute-myeloid-leukemia
#5
Colin M McGill, Patrick L Tomco, Regina M Ondrasik, Kaitlyn C Belknap, Gaelen K Dwyer, Daniel J Quinlan, Thomas A Kircher, Cheryl P Andam, Timothy J Brown, David F Claxton, Brian M Barth
Acute myeloid leukemia (AML) is an aggressive hematological malignancy that is one of the more common pediatric malignancies in addition to occurring with high incidence in the aging population. Unfortunately, these patient groups are quite sensitive to toxicity from chemotherapy. Northern Labrador tea, or Rhododendron tomentosum Harmaja (a.k.a. Ledum palustre subsp. decumbens) or "tundra tea," is a noteworthy medicinal plant used by indigenous peoples in Alaska, Canada, and Greenland to treat a diversity of ailments...
April 27, 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29687352/an-autopsy-report-of-an-adenoid-cystic-carcinoma-arising-in-the-trachea
#6
Gargi Kapatia, Kirti Gupta, Oshan Shrestha, Anil Kumar, Ashish Bhalla
While adenoid cystic carcinoma is a common malignancy to arise within the salivary glands (21.9%) (Kokemueller et al. in Int J Oral Maxillofac Surg 33:25-31, 2004), it is seldom encountered as a tracheal mass and represents < 1% of all lung cancers. Tracheal tumors are an uncommon cause of dyspnoea due to their relatively rare occurrence (Baydur and Gottlieb in JAMA 234:829-831, 1975). They pose considerable diagnostic challenge clinically as their symptoms mimics more commoner ailments like asthma and chronic bronchitis...
April 23, 2018: Head and Neck Pathology
https://www.readbyqxmd.com/read/29618912/effort-reward-imbalance-and-its-association-with-health-among-pluckers-in-a-tea-plantation-in-south-india
#7
Chitra Tomy, Naveen Ramesh, Farah N Fathima, Rodney L D'cunha, Kote A Chakravathi
Context: Work-related stress is associated with cardiovascular diseases, musculoskeletal disorders, psychological ailments, and work-related injuries. Imbalance between high effort and low reward at work can lead to work stress among plantation workers. Aims: To assess the effort-reward imbalance (ERI) among pluckers in tea plantations in South India and its association on chronic health problems, substance abuses, and workplace injuries. Settings and Design: A cross-sectional study was conducted among 346 tea pluckers from May to June 2015 in six selected tea plantations in Anamalai, South India...
September 2017: Indian Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29618445/assessment-of-children-immunization-pattern-in-children-hospital-lahore-pakistan
#8
Kalsoom Tariq, Rukiya Tariq
The basic aim is to assess immunization pattern of children up to 15 months of age. A cross-sectional study was conducted on 100 immunized children in Children hospital Lahore, Pakistan. Single dose 0.05ml to 0.1ml of BCG was recommended at the time of birth. Three doses of 0.5ml of Pneumococcal vaccine was given, coupled with the Penta-valent vaccine was given at 6 week, 10 week and 14 weeks of age. Two doses 0.5ml of measles vaccine was given at 9 & 15 months. Respondent's sex, age and the vaccinated children against diseases were analyzed in the form of percentages and frequency tables through statistical analysis in the software called SPSS version 16...
March 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29602155/cytokine-profile-in-autistic-patients
#9
Mohammad Mahdi Eftekharian, Soudeh Ghafouri-Fard, Rezvan Noroozi, Mir Davood Omrani, Shahram Arsang-Jang, Maziar Ganji, Vajiheh Gharzi, Hanieh Noroozi, Alireza Komaki, Mehrdokht Mazdeh, Mohammad Taheri
The etiology of Autism Spectrum Disorders (ASDs) as severe neurodevelopmental ailments is not known. However, several evidences point to dysregulation of immune system as an underlying cause of ASD. In the present study we evaluated the mRNA expression levels of TNF-α, TGF-β, IFN-γ, CXCL8, IL-1β, IL-2, 1L-4, IL-6, IL-17 in whole blood samples of 30 ASD patients and 41 age and sex-matched healthy subjects with means of real-time PCR. TNF-α, IL-6 and IL-17 have been shown to be significantly up-regulated in ASD patients compared with healthy subjects (P < 0...
March 27, 2018: Cytokine
https://www.readbyqxmd.com/read/29579345/the-effects-of-prebiotic-supplementation-on-weight-gain-diarrhoea-constipation-fever-and-respiratory-tract-infections-in-the-first-year-of-life
#10
Iraj Shahramian, Gholamreza Kalvandi, Hazhir Javaherizadeh, Manijeh Khalili, Noor Mohammad Noori, Mojtaba Delaramnasab, Ali Bazi
AIM: This study was conducted to evaluate the effect of prebiotics on some common clinical ailments in healthy term infants. METHODS: Sixty healthy-term, breastfed (BF) infants were included. Along with these infants, 120 healthy-term formula-fed infants were randomly assigned to either the prebiotic formula (PF, n = 60) or regular formula (RF, n = 60) groups. Ready-to-use prebiotic-supplemented formula containing galacto-oligosaccharides and polydextrose (ratio 1:1) was used...
March 26, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29579074/prevalence-and-determinants-of-self-medication-practice-among-selected-households-in-addis-ababa-community
#11
Mensur Shafie, Mebrahtu Eyasu, Kedija Muzeyin, Yoseph Worku, Sagrario Martín-Aragón
BACKGROUND AND AIM: Self-medication (SM) is one part of self-care which is known to contribute to primary health care. If practiced appropriately, it has major benefits for the consumers such as self-reliance and decreased expense. However, inappropriate practice can have potential dangers such as incorrect self-diagnosis, dangerous drug-drug interactions, incorrect manner of administration, incorrect dosage, incorrect choice of therapy, masking of a severe disease, and/or risk of dependence and abuse...
2018: PloS One
https://www.readbyqxmd.com/read/29571035/prevalence-and-age-wise-distribution-of-human-papillomavirus-type-16-18-infections-among-hospital-screened-women-of-a-peri-urban-area-in-west-bengal-impact-of-socio-demographic-factors
#12
Amrapali Bhattacharya, Shrinka Sen, Paramita Mandal, Sweta Sharma Saha, Somosree Sarkar, Om Prakash Pathak, Lena Biswas, Jayeeta Roy, Rimpa Banerjee, Ranita Roy Chowdhury, Manidip Pal, Ankur Mukherjee, Sharmila Sengupta
BACKGROUND: We undertook the current study on cervical Human Papillomavirus (HPV) prevalence along with cytology in women visiting the Gynecology Out-patient Department of a hospital for common gynecological ailments, subsequent to our earlier population-based study on HPV prevalence from India. METHODS: We analyzed data on cervical-cytology (Pap smears) and PCR-based molecular detection of HPV infection along with socio-demographic variables (N = 696). RESULTS: We identified 36...
March 20, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29570230/association-between-the-age-of-solid-food-introduction-and-eczema-a-systematic-review-and-a-meta-analysis
#13
Nilakshi T Waidyatillake, Shyamali C Dharmage, Katrina Allen, Gayan Bowatte, Robert Boyle, John Burgess, Jennifer Koplin, Vanessa Garcia-Larsen, Adrian J Lowe, Caroline Lodge
INTRODUCTION: Eczema is a common childhood ailment responsible for a considerable disease burden. Both timing of introduction to solid food and allergenic food are believed to be related to childhood eczema. Despite the growing body of evidence, the relationship between timing of any solid food introduction (allergenic and/or non-allergenic) and development of eczema has not previously been systematically reviewed. METHODS: PubMed and EMBASE databases were searched using food and eczema terms...
March 23, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29564213/establishing-minimum-clinically-important-difference-values-for-the-patient-reported-outcomes-measurement-information-system-physical-function-hip-disability-and-osteoarthritis-outcome-score-for-joint-reconstruction-and-knee-injury-and-osteoarthritis-outcome
#14
Man Hung, Jerry Bounsanga, Maren W Voss, Charles L Saltzman
AIM: To establish minimum clinically important difference (MCID) for measurements in an orthopaedic patient population with joint disorders. METHODS: Adult patients aged 18 years and older seeking care for joint conditions at an orthopaedic clinic took the Patient-Reported Outcomes Measurement Information System Physical Function (PROMIS® PF) computerized adaptive test (CAT), hip disability and osteoarthritis outcome score for joint reconstruction (HOOS JR), and the knee injury and osteoarthritis outcome score for joint reconstruction (KOOS JR) from February 2014 to April 2017...
March 18, 2018: World Journal of Orthopedics
https://www.readbyqxmd.com/read/29536960/topical-ear-drop-self-medication-practice-among-the-ear-nose-and-throat-patients-in-ido-ekiti-nigeria-a-cross-sectional-study
#15
Toye Gabriel Olajide, Kayode Shuaib Aremu, Olaide T Esan, Adepeju Oluwatona Dosunmu, Mustapha Muhammad Raji
Background: Self-medication is a common habit in our country; Nigeria, especially among patients with otorhinolaryngological disorders. Medication when taken wrongly may bring dire consequences to the individual, such as masking developing diseases and may cause many other undesirable effects. The aim of this study was to determine the prevalence and to analyze topical ear drop self-medication practices among respondents attending the Ear, Nose, and Throat Clinic of Federal Teaching Hospital Ido Ekiti, Nigeria...
April 2018: Annals of African Medicine
https://www.readbyqxmd.com/read/29510918/seroprevalence-of-anti-polio-antibodies-in-children-from-polio-high-risk-area-of-afghanistan-a-cross-sectional-survey-2017
#16
Imtiaz Hussain, Ondrej Mach, Nasir A Hamid, Zaid S Bhatti, Deborah D Moore, M Steven Oberste, Shahid Khan, Hasan Khan, William C Weldon, Roland W Sutter, Zulfiqar A Bhutta, Sajid B Soofi
BACKGROUND: Afghanistan is one of the remaining wild-poliovirus (WPV) endemic countries. We conducted a seroprevalence survey of anti-poliovirus antibodies in Kandahar Province. METHODS: Children in two age groups (6-11 months and 36-48 months) visiting Mirwais hospital in Kandahar for minor ailments unrelated to polio were enrolled. After obtaining informed consent, we collected venous blood and conducted neutralization assay to detect poliovirus neutralizing antibodies...
April 5, 2018: Vaccine
https://www.readbyqxmd.com/read/29509874/carbonyldb-a-curated-data-resource-of-protein-carbonylation-sites
#17
R Shyama Prasad Rao, Ning Zhang, Dong Xu, Ian Max Møller
Motivation: Oxidative stress and protein damage have been associated with over 200 human ailments including cancer, stroke, neuro-degenerative diseases, and aging (Fedorova et al., 2014. Mass Spectrom. Rev., 33, 79-97). Protein carbonylation, a chemically diverse oxidative post-translational modification (PTM), is widely considered as the biomarker for oxidative stress and protein damage. Despite their importance and extensive studies, no database/resource on carbonylated proteins/sites exists...
March 2, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29507574/general-self-efficacy-level-and-health-behaviours-in-women-over-the-age-of-45-years-who-have-undergone-osteoporosis-treatment
#18
Mariola Janiszewska, Teresa Kulik, Dorota Żołnierczuk-Kieliszek, Barłomiej Drop, Ewelina Firlej, Ilona Gajewska
Introduction: Contemporary people do not follow the civilisation development in every life domain, their lifestyle is not always healthy. Self-efficacy is the factor that plays an important role in undertaking actions towards struggling with the disease. The aim of the study: The aim of the study was to determine the relationship between the general self-efficacy level and health behaviours as well as chosen sociodemographic features in women over the age of 45 years who have undergone osteoporosis treatment...
September 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/29481563/economic-burden-of-cancer-in-india-evidence-from-cross-sectional-nationally-representative-household-survey-2014
#19
Sunil Rajpal, Abhishek Kumar, William Joe
With the ongoing demographic and epidemiological transition, cancer is emerging as a major public health concern in India. This paper uses nationally representative household survey to examine the overall prevalence and economic burden of cancer in India. The age-standardized prevalence of cancer is estimated to be 97 per 100,000 persons with greater prevalence in urban areas. The evidence suggests that cancer prevalence is highest among the elderly and also among females in the reproductive age groups. Cancer displays a significant socioeconomic gradient even after adjusting for age-sex specifics and clustering in a multilevel regression framework...
2018: PloS One
https://www.readbyqxmd.com/read/29467005/traditional-knowledge-on-herbal-drinks-among-indigenous-communities-in-azad-jammu-and-kashmir-pakistan
#20
Neelam Rashid, Rodrigue Castro Gbedomon, Mushtaq Ahmad, Valère Kolawolé Salako, Muhammad Zafar, Khafsa Malik
BACKGROUND: Traditional knowledge about the use of medicinal plants for herbal drinks (HDs) is not well documented in the Azad Kashmir region despite their widespread use. This study highlights the taxonomic diversity and traditional knowledge on medicinal plants used for HDs while examining the diversity of diseases treated with HDs in the study area. METHODS: Individual discussions were conducted with 255 informants (84 women and 171 men). Data gathered included (i) informant age and gender, (ii) HD species and respective plant parts used, (iii) health disorders treated, and (iv) mode of preparation and utilizations...
February 21, 2018: Journal of Ethnobiology and Ethnomedicine
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