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https://www.readbyqxmd.com/read/28651233/terminalia-bellirica-gaertn-roxb-fruit-mitigates-ccl4-induced-oxidative-stress-and-hepatotoxicity-in-rats
#1
Jayesh Kuriakose, Helen Lal Raisa, Vysakh A, Binil Eldhose, Latha M S
Terminalia bellirica (Gaertn.) Roxb. is a medicinal plant used for the treatment of various ailments in the traditional system of medicine like Ayurveda where it has been prescribed as a rejuvenator and general health tonic. The fruit of the plant is one of the components of the age old ayurvedic formulation-'Triphala'. The present study evaluates curative effect of aqueous acetone extract of Terminalia bellirica fruits (AATB) against CCl4 induced oxidative stress and liver damage in an animal model. Two doses of the fruit extract (200mg/kg body weight and 400mg/kg body weight) were investigated for the beneficial effects...
June 23, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28643176/a-promising-tool-in-retina-regeneration-current-perspectives-and-challenges-when-using-mesenchymal-progenitor-stem-cells-in-veterinary-and-human-ophthalmological-applications
#2
REVIEW
Anna Cislo-Pakuluk, Krzysztof Marycz
Visual impairment is a common ailment of the current world population, with more exposure to CCD screens and fluorescent lighting, approximately 285 billion people suffer from this deficiency and 13% of those are considered clinically blind. More common causes for visual impairment include age-related macular degeneration (AMD), glaucoma and diabetic retinopathy (Zhu et al. Molecular Medicine Reports, 2015; Kolb et al. 2007; Machalińska et al. Current Eye Research, 34(9),748-760, 2009) among a few. As cases of retinal and optic nerve diseases rise, it is vital to find a treatment, which has led to investigation of the therapeutic potential of various stem cells types (Bull et al...
June 22, 2017: Stem Cell Reviews
https://www.readbyqxmd.com/read/28596011/emmenagogue-properties-of-milicia-excelsa-welw-c-c-berg-moraceae-based-at-least-in-part-on-its-ability-to-correlate-the-activity-of-the-hypothalamic-pituitary-axis-to-that-of-the-ovaries
#3
Marie Alfrede Mvondo, Aude Jaelle Touomo Sakock, Sylvin Benjamin Ateba, Charline Florence Awounfack, Telesphore Nanbo Gueyo, Dieudonné Njamen
ETHNOPHARMACOLOGICAL RELEVANCE: Milicia excelsa (Welw.) C.C. Berg (Moraceae) is a medicinal plant recommended over tropical Africa as a cure for several ailments including amenorrhea. This is the hallmark of an ovarian lesion or a dysfunction of the hypothalamic-pituitary-ovarian axis which may lead to infertility, osteoporosis or endometrial cancer. However, regardless these traditional claims, no scientific report dealing with emmenagogue properties has been reported yet. AIM OF THE STUDY: To bring scientific evidence to the curative action of the plant, we proposed evaluating the effects of a root aqueous extract of Milicia excelsa on female Wistar rat sexual maturation...
June 6, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28586613/hyperlactetemia-and-its-trends-in-critically-ill-children-admitted-in-pediatric-intensive-care-unit-of-a-developing-country
#4
Qalab Abbas, Muhammad Tariq Jamil, Leena Jafri, Anwar Ul Haque, Vivek Khetpal
OBJECTIVE: There is increasing evidence that in setting of critical ailments clinical signs lag biomarkers like Lactate and hyperlactetemia can be the only marker for this disorder. This study was conducted to describe the incidence of hyperlactatemia in critically ill children and its association with outcome. METHODS: Retrospective review of medical records of all children who had their lactic acid (LA) levels measured during their admission in PICU from January 2014 to December 2015 was done...
October 2016: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28564651/pro-angiogenesis-therapy-and-aging-a-mini-review
#5
Charles T Ambrose
Apart from major illnesses and chronic afflictions, the elderly experience lesser ailments, such as muscle weakness, cold intolerance, and transient memory lapses. Physical signs in the aged include wrinkled skin and the slow healing of skin abrasions. These ailments and signs are grouped together because they may be due in part to an age-linked, waning microcirculation. A reduced capillary density (CD) throughout the body of aged people and animals has been reported in over 40 papers. The reduced CD is due in turn to declining levels of angiogenic growth factors (AGFs) throughout the body during old age, as documented in 7 reports in the literature...
June 1, 2017: Gerontology
https://www.readbyqxmd.com/read/28551561/oxidative-stress-and-respiratory-symptoms-due-to-human-exposure-to-polycyclic-aromatic-hydrocarbons-pahs-in-kumasi-ghana
#6
Nesta Bortey-Sam, Yoshinori Ikenaka, Osei Akoto, Shouta M M Nakayama, Kwadwo A Asante, Elvis Baidoo, Christian Obirikorang, Aksorn Saengtienchai, Norikazu Isoda, Collins Nimako, Hazuki Mizukawa, Mayumi Ishizuka
Studies of polycyclic aromatic hydrocarbons (PAHs) and its metabolites in PM10, soils, rat livers and cattle urine in Kumasi, Ghana, revealed high concentrations and cancer potency. In addition, WHO and IARC have reported an increase in cancer incidence and respiratory diseases in Ghana. Human urine were therefore collected from urban and control sites to: assess the health effects associated with PAHs exposure using malondialdehyde (MDA) and 8-hydroxy-2-deoxyguanosine (8-OHdG); identify any association between OH-PAHs, MDA, 8-OHdG with age and sex; and determine the relationship between PAHs exposure and occurrence of respiratory diseases...
May 25, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28546802/immunohistochemical-evaluation-of-oestrogen-receptors-%C3%AE-and-%C3%AE-in-epithelium-of-the-vaginal-mucous-membrane-in-women-after-oestrogen-therapy
#7
Beata Sawczuk, Maria Gołębiewska, Andrzej Mazurek, Lech Chyczewski
Oestrogens act on target cells through α and β receptors (ERα and ERβ). Expression of oestrogen receptors is associated with the age and menopausal condition of women. The aim of the study was an immunohistochemical evaluation of ERα and ERβ receptors in epithelium of the vaginal mucous membrane of women subjected to different forms of hormonal therapy (HTM). Oestrogen receptors ERα and ERβ were identified using immunohistochemical methods and evaluated in smears of vaginal mucous membranes collected from 60 patients subjected to HTM (including 20 patients after oral therapy, 20 patients after transdermal therapy, and 20 patients after vaginal therapy)...
March 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/28540898/assessment-of-quality-of-life-in-children-with-nephrotic-syndrome-at-a-teaching-hospital-in-south-india
#8
Sonia Agrawal, Sriram Krishnamurthy, Bijaya Nanda Naik
This study was conducted to assess the quality of life (QOL) in children between 2 and 18 years of age with primary idiopathic nephrotic syndrome (NS) using Pediatric Quality of Life Inventory (PedsQL 4.0 Generic Core Scales). This cross-sectional comparative study was conducted at a tertiary care hospital in South India between December 2014 and February 2015. In this questionnaire-based study, 50 children with primary idiopathic NS and an equal number of age-matched controls with other chronic ailments were recruited...
May 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28530057/-hansen-s-disease-in-israel
#9
REVIEW
Leon Gilead, Ruth Wexler
Hansen's disease (HD) is an anthropophylic, infectious, chronic disease, caused by Mycobacterium leprae. The systemic disease, affecting both males and females at any age, involves mainly the skin and the peripheral nerves located in the limbs close to the skin. Traditionally the treatment of HD patients was entrusted to dermatologists. Current drug therapy given at an early stage can prevent many of the complications, and enables patients to go on with life. In 95% of the population there is an innate immunity, which following exposure, enables the development of an effective immune response preventing the development of overt clinical disease...
October 2016: Harefuah
https://www.readbyqxmd.com/read/28520996/epidemiology-of-travellers-diarrhea
#10
Robert Steffen
Background: Travellers' diarrhea (TD) continues to be the most frequent health problem in travellers with destinations in lower income parts of the world as compared with where they reside, even if that risk has slightly decreased. Methods: A systematic review was published 18 months ago; now PubMed was searched for more recent publications relating to travel, diarrhea, epidemiology, incidence, risk. Results: A trend to decreasing incidence rates have been noted in this as compared with the last century, but TD remains frequent...
April 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28511366/gender-linked-metric-analysis-of-portal-vein-a-sonographic-appraisal
#11
Shikha Singh, Arvind Kumar Pankaj, Anita Rani, Pradeep Kumar Sharma, Puja Chauhan
INTRODUCTION: Portal hypertension is one of the most mystifying and disconcerting abdominal ailment. Ultrasonography (USG) is an effective diagnostic tool for its prompt management. Knowledge of normal calibre of portal vein in a local setting is essential as literature reports contrasting values in different regions. It helps in early diagnosis of portal hypertension even before it is clinically manifested thereby assisting clinicians and interventional radiologists in pertinent management...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28501003/phytochemicals-for-taming-agitated-immune-endocrine-neural-axis
#12
REVIEW
Seema Patel
Homeostasis of immune-endocrine-neural axis is paramount for human health. If this axis gets agitated due to age, genetic variations, environmental exposures or lifestyle assaults, a cascade of adverse reactions occurs in human body. Cytokines, hormones and neurotransmitters, the effector molecules of this axis behave erratically, leading to a gamut of neural, endocrine, autoimmune, and metabolic diseases. Current panel of drugs can tackle some of them but not in a sustainable, benign way as a myriad of side effects, causal of them have been documented...
July 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28484674/identification-of-demographic-factors-and-health-problems-that-affect-the-acceptance-of-disease-and-health-behaviors-of-patients-with-osteoarthritis
#13
Matylda Sierakowska, Izabela Wysocka-Skurska, Wojciech Kułak
INTRODUCTION: Osteoarthritis (OA) is one of the most common causes of musculoskeletal system's ailments. In the prevention of the disease and in its comprehensive treatment, proper health-related behavior becomes an extremely important factor for maintaining an optimal health condition. The aim of the study is to assess the relationship between the reported pain and the disability level, and the health-related behaviors undertaken by OA patients as well as their acceptance of the disease...
2017: PeerJ
https://www.readbyqxmd.com/read/28460651/transcatheter-closure-of-the-patent-foramen-ovale-in-children-intermediate-term-follow-up-results
#14
Kutay Sel, Hakan H Aykan, Derya Duman, Ebru Aypar, Süheyla Özkutlu, Dursun Alehan, Tevfik Karagöz
The patent foramen ovale is almost a normal anatomical hole between the atria with ~30% incidence in the general population. It has been suggested that the patent foramen ovale is the cause of some neurological events, which is explained by paradoxical embolism. Transcatheter closure of the patent foramen ovale is a common procedure in adult patients with cerebral ischaemic events, but there are limited data investigating the results in children. Between January, 2005 and February, 2014, 17 patients' patent foramen ovales were closed by the transcatheter approach in our department...
May 2, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28442807/epidemiology-and-clinico-investigative-study-of-organisms-causing-vaginal-discharge
#15
Swetha Venugopal, Kannan Gopalan, Asha Devi, A Kavitha
BACKGROUND: Abnormal vaginal discharge is a common clinical problem in reproductive age group. It is the second most common problem after abnormal uterine bleeding. It is a neglected health problem, most commonly caused due to vulvovaginal candidiasis, trichomoniasis, and bacterial vaginosis (BV). OBJECTIVES: The present study was conducted to determine the prevalence of common organisms causing vaginal discharge and also to know the variety of clinical presentation...
January 2017: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28411576/a-population-based-study-of-premorbid-scholastic-achievement-among-patients-with-psychiatric-disorders
#16
Vardit Zerem Ullman, Tzipi Hornik-Lurie, Abraham Reichenberg
Population-based studies of premorbid cognitive functioning in schizophrenia have found verbal deficits and low IQ scores. It remains unclear, however, whether premorbid deficits are specific to schizophrenia, compared with other psychiatric disorders. Moreover, studies using school-based measures are few and their results inconsistent. This study assesses the eighth-grade (ages 13-14; n=11, 418) scholastic performance of adults with psychiatric disorders (n=194, 1.7, particularly with schizophrenia (n=86, 0...
April 8, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28380067/does-tai-chi-relieve-fatigue-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#17
Yu Xiang, Liming Lu, Xiankun Chen, Zehuai Wen
BACKGROUND: Fatigue is not only a familiar symptom in our daily lives, but also a common ailment that affects all of our bodily systems. Several randomized controlled trials (RCTs) have proven Tai Chi to be beneficial for patients suffering from fatigue, however conclusive evidence is still lacking. A systematic review and meta-analysis was performed on all RCTs reporting the effects of Tai Chi for fatigue. METHODS: In the end of April 2016, seven electronic databases were searched for RCTs involving Tai Chi for fatigue...
2017: PloS One
https://www.readbyqxmd.com/read/28379126/-community-acquired-urinary-tract-infections-in-older-adults
#18
Alberto Francisco Leoni, Aida Monterisi, Paula G Acuña
Background Community acquired urinary tract infections (caUTI) in adults are common ailments. Older adults are prone to infectious diseases, diagnosis can be difficult, their etiologic and antimicrobial resistance are poorly known. Objectives To evaluate the incidence discriminated by sex, symptoms, and to determine pathogens and their antimicrobial resistance rate. Methods A retrospective, descriptive and comparative study. We analyze uricultures among 2013 in the Hospital Nacional de Clinicas (Córdoba-Argentina)...
2017: Revista de la Facultad de Ciencias Médicas
https://www.readbyqxmd.com/read/28378081/laparoscopy-assisted-distal-gastrectomy-is-feasible-also-for-elderly-patients-aged-80-years-and-over-effectiveness-and-long-term-prognosis
#19
Motohira Yoshida, Shigehiro Koga, Kei Ishimaru, Yuji Yamamoto, Yusuke Matsuno, Satoshi Akita, Jun Kuwabara, Kazufumi Tanigawa, Yuji Watanabe
BACKGROUND: Elderly patients usually have concurrent ailments, and the safety and effectiveness of laparoscopy-assisted distal gastrectomy (LADG) for these patients have been controversial. This study aimed to evaluate whether laparoscopy-assisted distal gastrectomy is safe and effective for elderly patients aged 80 years and over, as well as to clarify their long-term prognosis. METHODS: A total of 31 patients aged 80 years and over who underwent LADG in our hospital were retrospectively reviewed...
April 4, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28375088/effect-of-viscum-schimperi-on-advanced-glycation-endproducts-formation
#20
Hossam Mohamed Abdallah, Doha Omar ALGhamdi, Maab Siddiq Al-Salem, Maryam Alattas, Hany Mohamed El-Bassossy, Abdulrahman Mohammed Alahdal
Diabetes is a disease characterized by elevated uncontrolled glucose level. Hyperglycemia results in diabetic complication due to a reaction between sugar and amino acid of proteins to form advanced glycation endproducts (AGEs) in different tissues. Medicinal plants are considered as a great source of bioactive compounds that affect many ailments. In this regard; AGEs formation could be inhibited by many bioactive compounds isolated from medicinal plants. Viscum schimperi Engl. is a plant belongs to Loranthaceae and known for its antidiabetic activity...
November 2016: Pakistan Journal of Pharmaceutical Sciences
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