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https://www.readbyqxmd.com/read/28211649/insufficient-sleep-in-adolescents-causes-and-consequences
#1
Judith A Owens, Miriam R Weiss
Insufficient sleep poses an important and complicated set of health risks in the adolescent population. Not only is deficient sleep (defined as both sleep duration inadequate to meet sleep needs and sleep timing misaligned with the body's circadian rhythms) at epidemic levels in this population, but the contributing factors are both complex and numerous and there are a myriad of negative physical and mental health, safety and performance consequences. Causes of inadequate sleep identified in this population include internal biological processes such as the normal shift (delay) in circadian rhythm that occurs in association with puberty and a developmentally-based slowing of the "sleep drive", and external factors including extracurricular activities, excessive homework load, evening use of electronic media, caffeine intake and early school start times...
February 17, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28211596/the-structure-of-adult-adhd
#2
Lenard A Adler, Stephen V Faraone, Thomas J Spencer, Patricia Berglund, Samuel Alperin, Ronald C Kessler
Although DSM-5 stipulates that symptoms of attention-deficit hyperactivity disorder (ADHD) are the same for adults as children, clinical observations suggest that adults have more diverse deficits than children in higher-level executive functioning and emotional control. Previous psychometric analyses to evaluate these observations have been limited in ways addressed in the current study, which analyzes the structure of an expanded set of adult ADHD symptoms in three pooled US samples: a national household sample, a sample of health plan members, and a sample of adults referred for evaluation at an adult ADHD clinic...
February 17, 2017: International Journal of Methods in Psychiatric Research
https://www.readbyqxmd.com/read/28207468/significant-differences-in-the-bone-of-an-isogenic-inbred-versus-nonisogenic-outbred-murine-mandible-a-study-in-rigor-and-reproducibility
#3
Edward G Carey, Sagar S Deshpande, Kevin M Urlaub, Alexander R Zheutlin, Noah S Nelson, Alexis Donneys, Stephen Y Kang, Kathleen K Gallagher, Peter A Felice, Catherine N Tchanque-Fossuo, Steven R Buchman
Inattention to differences between animal strains is a potential cause of irreproducibility of basic science investigations. Accordingly, the authors' laboratory sought to ensure that cross-comparisons of results generated from studies of mandibular physiology utilizing the Sprague Dawley and Lewis rat strains are valid. The authors specifically investigated baseline histomorphometrics, bone mineral density, and biomechanical strength of the unaltered endogenous mandibles of the inbred, isogenic Lewis rat, and the outbred, nonisogenic Sprague Dawley rat to determine if they are indeed equal...
February 15, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28199415/temperament-in-infancy-and-behavioral-and-emotional-problems-at-age-5-5-the-eden-mother-child-cohort
#4
Xian Abulizi, Laura Pryor, Grégory Michel, Maria Melchior, Judith van der Waerden
OBJECTIVE: Early temperamental characteristics may influence children's developmental pathways and predict future psychopathology. However, the environmental context may also shape or interact with infant temperament and indirectly contribute to increased vulnerability to adverse developmental outcomes. The aim of the present study is to explore the long-term contribution of temperamental traits at twelve months of age to the presence of emotional and behavioral problems later in childhood, and whether this association varies with the child's sex, parental separation, family socioeconomic status and maternal depression...
2017: PloS One
https://www.readbyqxmd.com/read/28194394/assessment-of-school-readiness-in-chronic-cholestatic-liver-disease-a-pilot-study-examining-children-with-and-without-liver-transplantation
#5
Anna Gold, Alaine Rogers, Elizabeth Cruchley, Stephanie Rankin, Arpita Parmar, Binita M Kamath, Yaron Avitzur, Vicky Lee Ng
Background. Assessment of school readiness evaluates physical, social-emotional, and neuropsychological domains essential for educational success. Cognitive testing of preschool aged children with chronic liver disease may guide more timely interventions and focused efforts by health care providers. Patients and Methods. Children with chronic cholestatic liver disease diagnosed as an infant and still with their native liver (NL) and children who received a liver transplant (LT) before age of 2 years underwent testing with a battery of well-validated pediatric psychometric measures...
2017: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28191983/mental-health-of-extremely-low-birth-weight-survivors-a-systematic-review-and-meta-analysis
#6
Karen J Mathewson, Cheryl H T Chow, Kathleen G Dobson, Eliza I Pope, Louis A Schmidt, Ryan J Van Lieshout
Although individuals born at extremely low birth weight (ELBW; < 1,000 g) are the most vulnerable of all preterm survivors, their risk for mental health problems across the life span has not been systematically reviewed. The primary objective of this systematic review and meta-analysis was to ascertain whether the risk for mental health problems is greater for ELBW survivors than their normal birth weight (NBW) peers in childhood, adolescence, and adulthood. Forty-one studies assessing 2,712 ELBW children, adolescents, and adults and 11,127 NBW controls were reviewed...
February 13, 2017: Psychological Bulletin
https://www.readbyqxmd.com/read/28190673/interplay-between-supramodal-attentional-control-and-capacity-limits-in-the-low-level-visual-processors-modulate-the-tendency-to-inattention
#7
Massimiliano Papera, Anne Richards
When engaged in a demanding task, individuals may neglect unexpected visual stimuli presented concomitantly. Here we use a change detection task to show that propensity to inattention is associated with a flexible allocation of attentional resources to filter and represent visual information. This was reflected by N2 posterior contralateral (N2pc) and contralateral delay activity (CDA) respectively, but also during high-order reorienting of attentional resources (known as anterior directing attention negativity, ADAN)...
February 9, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28184164/assessment-and-monitoring-of-treatment-response-in-adult-adhd-patients-current-perspectives
#8
REVIEW
J Russell Ramsay
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental syndrome that emerges in childhood or early adolescence and persists into adulthood for a majority of individuals. There are many other adults with ADHD who may not seek out evaluation and treatment until adulthood, having been able to "get by" before struggling with inattention, hyperactivity, and/or impulsivity in adulthood, in addition to facing the associated features of disorganization, poor time management, and procrastination among many others...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28179105/a-prenatal-nicotine-exposure-mouse-model-of-methylphenidate-responsive-adhd-associated-cognitive-phenotypes
#9
Jinmin Zhu, Fangfang Fan, Deirdre M McCarthy, Lin Zhang, Elisa N Cannon, Thomas J Spencer, Joseph Biederman, Pradeep G Bhide
Prenatal exposure to nicotine via cigarette smoke or other forms of tobacco use is a significant environmental risk factor for attention deficit hyperactivity disorder (ADHD). The neurobiological mechanisms underlying the link between prenatal nicotine exposure (PNE) and ADHD are not well understood. Animal models, especially rodent models, are beginning to bridge this gap in knowledge. Although ADHD is characterized by hyperactivity, inattention, impulsivity and working memory deficits, the majority of the animal models are based on only one or two ADHD associated phenotypes, in particular, hyperactivity or inattention...
February 4, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28176178/are-anxiety-disorders-in-children-and-adolescents-less-impairing-than-adhd-and-autism-spectrum-disorders-associations-with-child-quality-of-life-and-parental-stress-and-psychopathology
#10
Liesbeth G E Telman, Francisca J A van Steensel, Marija Maric, Susan M Bögels
We compared clinically referred children with anxiety disorders (AD; n = 63) to children with autism spectrum disorder (ASD; n = 39), ADHD Combined (ADHD-C; n = 62), ADHD Predominantly Inattentive (ADHD-I; n = 64), and typically developing children (n = 42) on child quality of life (QOL), paternal and maternal psychopathology and parental stress. Diagnoses were based on DSM-IV-TR criteria. Multilevel analyses showed that QOL in AD was higher on school and social functioning, compared to respectively ADHD and ASD, and lower compared to normal controls on all five domains...
February 7, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/28173729/structural-and-functional-abnormalities-in-children-with-adhd-a-focus-on-subgenual-anterior-cingulate-cortex
#11
Chenyang Zhan, Yuhong Liu, Kai Wu, Yu Gao, Xiaobo Li
Attention-Deficit/Hyperactivity Disorder (ADHD), characterized by developmentally inappropriate inattention, hyperactivity/impulsivity, or a combination of both, is a major public health problem. Neuroimaging studies have revealed associations of these cognitive impairments with structural and functional deficits all over the brain. Existing findings are not fully consistent due to the heterogeneity of study samples and diversity of research techniques. In the current study, we propose to utilize a multi-modal MRI approach to study the structural and functional brain networks in children with ADHD-combined type (ADHD-C) with a focus on the subgenual anterior cingulate cortex (sgACC)...
February 7, 2017: Brain Connectivity
https://www.readbyqxmd.com/read/28167942/distinct-cytokine-and-chemokine-profiles-in-autism-spectrum-disorders
#12
Yvonne M Y Han, Winnie K Y Cheung, Chun Kwok Wong, Sophia L Sze, Timmy W S Cheng, Michael K Yeung, Agnes S Chan
Previous studies have shown that immunological factors are involved in the pathogenesis of autism spectrum disorders (ASDs). However, this research has been conducted almost exclusively in Western contexts, and only a handful of studies on immune measures have been conducted in Asian populations, such as Chinese populations. The present study examined whether immunological abnormalities are associated with cognitive deficits and problem behaviors in Chinese children with ASD and whether these children show different immunological profiles...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28166888/how-much-time-do-drivers-need-to-obtain-situation-awareness-a-laboratory-based-study-of-automated-driving
#13
Zhenji Lu, Xander Coster, Joost de Winter
Drivers of automated cars may occasionally need to take back manual control after a period of inattentiveness. At present, it is unknown how long it takes to build up situation awareness of a traffic situation. In this study, 34 participants were presented with animated video clips of traffic situations on a three-lane road, from an egocentric viewpoint on a monitor equipped with eye tracker. Each participant viewed 24 videos of different durations (1, 3, 7, 9, 12, or 20 s). After each video, participants reproduced the end of the video by placing cars in a top-down view, and indicated the relative speeds of the placed cars with respect to the ego-vehicle...
April 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28164728/adhd-and-sct-symptomatology-in-relation-to-college-students-use-of-self-regulated-learning-strategies
#14
Christopher R Shelton, William E Addison, Cynthia M Hartung
OBJECTIVE: The present study examined the relation between self-regulated learning (SRL) strategies and ADHD and sluggish cognitive tempo (SCT) symptomatology. METHOD: Participants were 303 college students, aged 18 to 25 ( M = 20.04, SD = 1.45), from a Midwestern university who completed the Barkley Adult ADHD Rating Scale-IV (BAARS-IV), and a shortened, generalized version of the Motivated Strategies for Learning Questionnaire (MSLQ). RESULTS: Among college students, inattention symptomatology was consistently predictive of deficits in use of value, expectancy, and self-regulation strategies, while SCT symptomatology was only predictive of deficits in the use of self-regulation strategies...
February 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28162039/prevalence-patterns-and-predictors-of-sleep-problems-and-daytime-sleepiness-in-young-adolescents-with-adhd
#15
Joshua M Langberg, Stephen J Molitor, Lauren E Oddo, Hana-May Eadeh, Melissa R Dvorsky, Stephen P Becker
OBJECTIVE: The primary objective of this study was to evaluate the prevalence of multiple types of sleep problems in young adolescents with ADHD. METHOD: Adolescents comprehensively diagnosed with ADHD (N = 262) and their caregivers completed well-validated measures of sleep problems and daytime sleepiness. Participants also completed measures related to medication use, comorbidities, and other factors that could predict sleep problems. RESULTS: Daytime sleepiness was by far the most common sleep problem, with 37% of adolescents meeting the clinical threshold according to parent report and 42% according to adolescent report...
January 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28161246/partial-agonism-at-the-%C3%AE-7-nicotinic-acetylcholine-receptor-improves-attention-impulsive-action-and-vigilance-in-low-attentive-rats
#16
Andrew Hayward, Lisa Adamson, Joanna C Neill
Inattention is a disabling symptom in conditions such as schizophrenia and attention deficit/hyperactivity disorder. Nicotine can improve attention and vigilance, but is unsuitable for clinical use due to abuse liability. Genetic knockout of the α7 nicotinic acetylcholine receptor (nAChR) induces attention deficits therefore selective agonism may improve attention, without the abuse liability associated with nicotine. The α7 nAChR partial agonist encenicline (formerly EVP-6124) enhances memory in rodents and humans...
February 1, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28159711/quality-in-dual-energy-x-ray-absorptiometry-scans
#17
Sarah L Morgan, Ginnie L Prater
Dual-energy X-ray absorptiometry (DXA) is the gold standard for measuring bone mineral density (BMD), making the diagnosis of osteoporosis, and for monitoring changes in BMD over time. DXA data are also used in the determination of fracture risk. Procedural steps in DXA scanning can be broken down into scan acquisition, analysis, interpretation, and reporting. Careful attention to quality control pertaining to these procedural steps should theoretically be beneficial in patient management. Inattention to procedural steps and errors that may occur at each step has the possibility of providing information that would inform inappropriate clinical decisions, generating unnecessary healthcare expenses and ultimately causing avoidable harm to patients...
January 31, 2017: Bone
https://www.readbyqxmd.com/read/28153568/the-relationship-between-motor-performance-and-parent-rated-executive-functioning-in-3-to-5-year-old-children-what-is-the-role-of-confounding-variables
#18
Suzanne Houwen, Gerda van der Veer, Jan Visser, Marja Cantell
It is generally agreed that motor performance and executive functioning (EF) are intertwined. As the literature on this issue concerning preschool children is scarce, we examined the relationship between motor performance and parent-rated EF in a sample of 3- to 5-year-old children with different levels of motor skill proficiency, while controlling for age, gender, socio-economic status (SES), and attention-deficit-hyperactivity disorder (ADHD) symptomatology. EF was reported by parents of 153 children (mean age 4years 1months, SD 8months; 75 male) by means of the Behaviour Rating Inventory of Executive Function-Preschool version (BRIEF-P)...
January 30, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28151942/caregiver-related-predictors-of-thermal-burn-injuries-among-iranian-children-a-case-control-study
#19
Homayoun Sadeghi-Bazargani, Reza Mohammadi, Erfan Ayubi, Amir Almasi-Hashiani, Reza Pakzad, Mark J M Sullman, Saeid Safiri
PURPOSE: Burns are a common and preventable cause of injury in children. The aim of this study was to investigate child and caregiver characteristics which may predict childhood burn injuries among Iranian children and to examine whether confounding exists among these predictors. METHODS: A hospital based case-control study was conducted using 281 burn victims and 273 hospital-based controls, which were matched by age, gender and place of residence (rural/urban)...
2017: PloS One
https://www.readbyqxmd.com/read/28148581/delirium-a-guide-for-the-general-physician
#20
Oliver M Todd, Elizabeth A Teale
Delirium describes a sudden onset change in mental status of fluctuating course. This is a state of altered consciousness characterised chiefly by inattention or lack of arousal, but can also include new impairment of language, perception and behaviour. Certain predisposing factors can make an individual more susceptible to delirium in the face of a stressor. Stressors include direct insults to the brain, insults peripheral to the brain or external changes in the environment of an individual. Delirium is varied in its presentation, and can be categorised by the psychomotor profile as: hyperactive type (overly vigilant, agitated, often wandersome), hypoactive type (sedate or withdrawn) or mixed types...
February 2017: Clinical Medicine: Journal of the Royal College of Physicians of London
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