Ping Chen, Dirk E M Geurts, Jessica I Määttä, Ruben van den Bosch, Lieke Hofmans, Danae Papadopetraki, Hanneke den Ouden, Roshan Cools
Interaction between Pavlovian and instrumental control systems is key for adaptive motivated behavior, but also plays an important role in various neuropsychiatric disorders, including depression, addiction, and anxiety. Here, we employed the flouorodopa positron emission tomography ([¹⁸F]-DOPA PET) in healthy participants ( N = 100) to assess whether dopamine synthesis capacity (Ki ), specifically in the ventral striatum, accounts for individual variation in Pavlovian-to-instrumental transfer (PIT)...
January 12, 2023: Behavioral Neuroscience