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https://www.readbyqxmd.com/read/28538982/association-of-late-adolescent-personality-with-risk-for-subsequent-serious-mental-illness-among-men-in-a-swedish-nationwide-cohort-study
#1
Joseph F Hayes, David P J Osborn, Glyn Lewis, Christina Dalman, Andreas Lundin
Importance: Understanding of personality as an independent risk factor for serious mental illness (SMI) remains limited. Recently, overlap between the polygenic basis for specific personality traits and specific SMIs has been identified. Objective: To determine the association of the adolescent personality domains of social maturity, mental energy, and emotional stability with later diagnosis of SMI. Design, Setting, and Participants: This longitudinal cohort study enrolled Swedish male military conscripts aged 18 or 19 years from January 1, 1974, through December 31, 1997...
May 24, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28538961/validation-of-the-intelligibility-in-context-scale-for-jamaican-creole-speaking-preschoolers
#2
Karla N Washington, Megan M McDonald, Sharynne McLeod, Kathryn Crowe, Hubert Devonish
Purpose: To describe validation of the Intelligibility in Context Scale (ICS; McLeod, Harrison, & McCormack, 2012a) and ICS-Jamaican Creole (ICS-JC; McLeod, Harrison, & McCormack, 2012b) in a sample of typically developing 3- to 6-year-old Jamaicans. Method: One-hundred and forty-five preschooler-parent dyads participated in the study. Parents completed the 7-item ICS (n = 145) and ICS-JC (n = 98) to rate children's speech intelligibility (5-point scale) across communication partners (parents, immediate family, extended family, friends, acquaintances, strangers)...
May 23, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28538942/anti-ttg-among-children-with-chronic-functional-constipation-unresponsive-to-6-weeks-of-treatment-of-constipation
#3
Nooshin Sadjadei, Samaneh Hosseinmardy, Mehran Hakimzadeh, Tahereh Ziaei Kajbaf, Hazhir Javaherizadeh
BACKGROUND: Celiac disease is a glutten induced enteropathy. Some authors recommended screening celiac in children with constipation. There are studies to evaluate celiac disease in children with constipation. But most of them included children regardless to treatment failure. OBJECTIVE: The aim of this study was to evaluate frequency of elevated anti TTG in children with constipation after failure to improve during 6 week of appropriate treatment of constipation...
May 18, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28538929/stressors-influence-work-ability-in-different-age-groups-of-nursing-professionals-2-year-follow-up
#4
Maria Carmen Martinez, Maria do Rosário Dias de Oliveira Latorre, Frida Marina Fischer
Work stressors influence work ability - WA - and increasing age is associated with functional aging. We sought to establish whether work stressors differentially influence WA in young and aging nursing professionals. A cohort (2009-2011) composed of 304 workers at a hospital in Sao Paulo responded questionnaires Effort-Reward Imbalance (ERI), Job Stress Scale (JSS), Work-Related Activities That May Contribute To Job-Related Pain and/or Injury (WRAPI) and Work Ability Index (WAI). Changes in perceived exposure to stressors in each age group (< 45 and ≥ 45 years old) were compared to delta-WAI (difference between initial and final WAI score) by means of the Mann-Whitney test...
May 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28538893/lower-lip-reconstruction-using-a-skin-mucosa-abbe-estlander-flap-after-squamous-cell-carcinoma-excision
#5
Husein Husein-ElAhmed, Rafael Armijo-Lozano
Lips are structures that play an essential role in aesthetics and in different functions such as nutrition and speech. The complex anatomy of the lips - with three different layers composed of skin, mucosa, and muscles - makes surgical management of this area a therapeutic challenge. The use of flaps for the reconstruction of large defects with low risk of necrosis is possible given the abundant blood supply of the lips. We report a case of surgical reconstruction of the lower lip after the excision of a severe squamous cell carcinoma using a skin-mucosa Abbe-Estlander flap with a satisfactory final outcome...
March 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28538877/effects-of-isotretinoin-on-the-olfactory-function-in-patients-with-acne
#6
Demet Kartal, Mehmet Yaşar, Levent Kartal, Ibrahim Özcan, Murat Borlu
Background: Isotretinoin is a synthetic analog of vitamin A. Recent studies support a role for retinoic acid in the recovery of olfactory function following injury in mice. Objective: This study aimed at determining the effect of isotretinoin on olfactory function in patients who have acne and are otherwise healthy. Methods: Forty-five patients (aged 25-40 years) with acne were included in the study. All patients underwent a rhinological examination...
March 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28538871/what-do-cochrane-systematic-reviews-say-about-interventions-for-autism-spectrum-disorders
#7
Larissa Lyra, Luiz Eduardo Rizzo, Camila Sá Sunahara, Daniela Vianna Pachito, Carolina de Oliveira Cruz Latorraca, Ana Luiza Cabrera Martimbianco, Rachel Riera
CONTEXT AND OBJECTIVE: Autism spectrum disorders (ASDs) include autistic disorder, Asperger's disorder and pervasive developmental disorder. The manifestations of ASDs can have an important impact on learning and social functioning that may persist during adulthood. The aim here was to summarize the evidence from Cochrane systematic reviews on interventions for ASDs. DESIGN AND SETTING: Review of systematic reviews, conducted within the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo...
March 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28538837/microrna-455-suppresses-the-oncogenic-function-of-hdac2-in-human-colorectal-cancer
#8
Q D Mao, W Zhang, K Zhao, B Cao, H Yuan, L Z Wei, M Q Song, X S Liu
Colorectal cancer (CRC) is the fourth leading cause of cancer-induced mortality. Histone deacetylase 2 (HDAC2) is involved in prognosis and therapy of CRC. This study aimed to explore novel therapeutic targets for CRC. The alteration of HDAC2 expression in CRC tissues was estimated by qRT-PCR. After lentivirus transfection, HDAC2 knockdown was confirmed by western blot analysis. The effect of HDAC2 knockdown on cell proliferation was then assessed by 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay...
May 18, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28538833/research-about-suppression-effect-and-auditory-processing-in-individuals-who-stutter
#9
Cláudia Fassin Arcuri, Ana Maria Schiefer, Marisa Frasson de Azevedo
Purpose: To verify the auditory processing abilities and occurrence of the suppression effect of Otoacoustic Emissions (OAE) in individuals who stutter. Methods: The study sample comprised 15 adult individuals who stutter, aged 18-40 years, with stuttering severity ranging from mild to severe, paired according to gender, age, and schooling with individuals without speech complaint or disorder. All participants underwent conventional clinical evaluation, specific stuttering assessment, and basic (audiometry, imitanciometry, and measurement of acoustic reflexes) and specific (auditory processing evaluation and measurement of suppression effect of OAEs) audiological assessments...
May 22, 2017: CoDAS
https://www.readbyqxmd.com/read/28538828/families-perception-of-children-adolescents-with-language-impairment-through-the-international-classification-of-functioning-disability-and-health-icf-cy
#10
Daniele Theodoro Ostroschi, Maria de Lurdes Zanolli, Regina Yu Shon Chun
Purpose: To investigate the perception of family members regarding linguistic conditions and social participation of children and adolescents with speech and language impairments using the International Classification of Functioning, Disability and Health - Children and Youth Version (ICF-CY). Methods: Quali-quantitative approach research, in which a survey of medical records of 24 children/adolescents undergoing speech-language therapy and interviews with their family members was conducted...
May 22, 2017: CoDAS
https://www.readbyqxmd.com/read/28538826/functional-change-in-the-pattern-of-swallowing-through-the-performance-of-orofacial-exercises
#11
Irina Claudia Fernandes Alves, Claudia Regina Furquim de Andrade
Purpose: The objective was to determine if there was functional improvement of swallowing pattern in subjects identified with risk of oropharyngeal dysphagia after four weeks of specific oropharyngeal exercises. These exercises have pre-determined intensity and duration. Methods: It is a longitudinal study of functional effect, determined by initial and final comparative measures. Participants were adults and elderly, selected in a period of 24 months. A total of 68 participants were included...
May 22, 2017: CoDAS
https://www.readbyqxmd.com/read/28538825/cochlear-function-in-students-exposed-to-pesticides
#12
Tatiana Rodrigues Garcia, Maria Isabel Kós Pinheiro de Andrade, Silvana Maria Frota, Maria de Fátima Miranda, Raphael Mendonça Guimarães, Armando Meyer
Purpose: To estimate the degree of association between exposure to pesticides and the risk of alteration in cochlear function in students exposed to pesticides. Methods: This study evaluated individuals aged 8 to 30, of both genders, residing in an area of heavy pesticide use in the town of Nova Friburgo, Rio de Janeiro State. Each study participant answered a questionnaire to assess their degree of pesticide exposure. To evaluate cochlear function, audiometry exams were performed, including transient evoked otoacoustic emissions (TEOAEs) and distortion product otoacoustic emissions (DPOAEs)...
May 15, 2017: CoDAS
https://www.readbyqxmd.com/read/28538822/association-between-harmful-oral-habits-and-the-structures-and-functions-of-the-stomatognathic-system-perception-of-parents-guardians
#13
Thayse Steffen Pereira, Fabiana de Oliveira, Maria Cristina de Almeida Freitas Cardoso
Purpose: To verify the occurrence and associate the presence and duration of harmful oral habits with the structures and functions of the stomatognathic system. Methods: This is a cross-sectional, exploratory study. Participants' participation was formalized by the signing of an Informed Consent Form. The non-probabilistic sample comprised 289 children aged one to 12 years assisted at a Family Health Strategy unit. The data were obtained through a questionnaire to identify harmful oral habits applied to the children's parents and/or guardians...
May 15, 2017: CoDAS
https://www.readbyqxmd.com/read/28538819/how-strong-is-the-relationship-between-rainfall-variability-and-caatinga-productivity-a-case-study-under-a-changing-climate
#14
Cleber Salimon, Liana Anderson
Despite the knowledge of the influence of rainfall on vegetation dynamics in semiarid tropical Brazil, few studies address and explore quantitatively the various aspects of this relationship. Moreover, Northeast Brazil is expected to have its rainfall reduced by as much as 60% until the end of the 21st Century, under scenario AII of the IPCC Report 2010. We sampled and analyzed satellite-derived monthly rainfall and a vegetation index data for 40 sites with natural vegetation cover in Paraíba State, Brazil from 2001 to 2012...
May 22, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28538803/comparative-study-between-standard-and-inside-out-vein-graft-techniques-on-sciatic-nerve-repair-of-rats-muscular-and-functional-analysis
#15
Cleuber Rodrigo de Souza Bueno, Mizael Pereira, Idvaldo Aparecido, Rogerio Leone Buchaim, Jesus Carlos Andreo, Antônio de Castro Rodrigues, Geraldo Marco
Purpose: To compare the functional result of standart vein grafts and inside-out vein graft technique on sciatic nerve repair. Methods: We used 24 male Wistar rats divided into 4 groups: control group (CG), standard vein graft group (SVG), Inside-out vein graft group (IOVG) and denervated Group (DG). SVG, IOVG and DG underwent total section of the sciatic nerve, SVG and IOVG however underwent nerve repair surgery using a graft with normal jugular vein and inside-out jugular vein, respectively...
April 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28538801/effects-of-hyperbaric-oxygen-and-nerve-growth-factor-on-the-long-term-neural-behavior-of-neonatal-rats-with-hypoxic-ischemic-brain-damage
#16
Lixia Wei, Qing Ren, Yongjun Zhang, Jiwen Wang
Purpose: To evaluate the effects of HBO (Hyperbaric oxygen) and NGF (Nerve growth factor) on the long-term neural behavior of neonatal rats with HIBD (Neonatal hypoxic ischemic brain damage). Methods: The HIBD model was produced by ligating the right common carotid artery of 7 days old SD (Sprague-Dawley) rats followed by 8% O2 + 92% N2 for 2h. Totally 40 rats were randomly divided into 5 groups including sham-operated group, HIBD control group, HBO treated group, NGF treated group and NGF + HBO treated group...
April 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28538762/papillary-muscle-free-strain-in-patients-with-severe-degenerative-and-functional-mitral-regurgitation
#17
Alev Kılıcgedik, Gokhan Kahveci, Ahmet Seyfeddin Gurbuz, Can Yucel Karabay, Ahmet Guler, Suleyman Cagan Efe, Soe Moe Aung, Ugur Arslantas, Serdar Demir, Ibrahim Akin Izgi, Cevat Kirma
Fundamento: The role of papillary muscle function in severe mitral regurgitation with preserved and reduced left ventricular ejection fraction and the method of choice to evaluate PM have still been the subjects of controversy. Objectives: To evaluate and compare papillary muscle function in and between patients with severe degenerative and functional mitral regurgitation by using the free strain method. Methods: 64 patients with severe mitral regurgitation - 39 patients with degenerative mitral regurgitation (DMR group) and 25 patients with severe functional mitral regurgitation (FMR group) - and 30 control subjects (control group) were included in the study...
April 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28538761/effects-of-continuous-and-accumulated-exercise-on-endothelial-function-in-rat-aorta
#18
Juliana Edwiges Martinez, Elane de Fátima Taipeiro, Agnaldo Bruno Chies
Background: The practice of exercise in short bouts repeated throughout the day may be an alternative strategy to lift people out of physical inactivity. Objective: to evaluate if accumulated exercise, as occurs in continuous exercise training, improve endothelial function in rat aorta. Methods: Wistar male rats were divided into three groups: continuous exercise (CEx, 1 hour on the treadmill) or accumulated exercise (AEx, 4 bouts of 15 minutes / day) for 5 days/week for 8 weeks, or sedentary (SED)...
April 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28538738/solid-phase-synthesis-cyclization-and-site-specific-functionalization-of-aziridine-containing-tetrapeptides
#19
Benjamin K W Chung, Christopher J White, Andrei K Yudin
Cyclic tetrapeptides comprise a potent and selective class of molecules with a wide range of biological activities, including the phytotoxic activity of tentoxin and the histone deacetylase (HDAC) inhibitory effects of chlamydocin. The incorporation of a functional aziridine group within cyclic peptides enables their conformational control and allows for late-stage and site-selective functionalization of these molecules, thereby creating the potential for covalent protein labeling. This protocol describes the solid-phase synthesis, cyclization, and site-specific structural modification of aziridine-containing tetrapeptides...
June 2017: Nature Protocols
https://www.readbyqxmd.com/read/28538737/lymphatic-endothelial-s1p-promotes-mitochondrial-function-and-survival-in-naive-t-cells
#20
Alejandra Mendoza, Victoria Fang, Cynthia Chen, Madhavika Serasinghe, Akanksha Verma, James Muller, V Sai Chaluvadi, Michael L Dustin, Timothy Hla, Olivier Elemento, Jerry E Chipuk, Susan R Schwab
Effective adaptive immune responses require a large repertoire of naive T cells that migrate throughout the body, rapidly identifying almost any foreign peptide. Because the production of T cells declines with age, naive T cells must be long-lived. However, it remains unclear how naive T cells survive for years while constantly travelling. The chemoattractant sphingosine 1-phosphate (S1P) guides T cell circulation among secondary lymphoid organs, including spleen, lymph nodes and Peyer's patches, where T cells search for antigens...
May 24, 2017: Nature
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