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JOURNAL ARTICLE
Jill Davis, Rubeen Israni, Keith A Betts, Fan Mu, Erin E Cook, Deborah Anzalone, Harold Szerlip, Lei Yin, Gabriel I Uwaifo, Eric Q Wu
INTRODUCTION: Hyperkalemia is often managed in the emergency department (ED) and it is important to understand how ED management and post-discharge outcomes vary by hyperkalemia severity. This study was conducted to characterize ED management and post-discharge outcomes across hyperkalemia severities. METHODS: Adults with an ED visit with hyperkalemia (at least one serum potassium lab measure above 5.0 mEq/L) were selected from US electronic medical record data (2012-2018)...
February 2022: Advances in Therapy
#22
Robert J Lennox, Samuel Westrelin, Allan T Souza, Marek Šmejkal, Milan Říha, Marie Prchalová, Ran Nathan, Barbara Koeck, Shaun Killen, Ivan Jarić, Karl Gjelland, Jack Hollins, Gustav Hellstrom, Henry Hansen, Steven J Cooke, David Boukal, Jill L Brooks, Tomas Brodin, Henrik Baktoft, Timo Adam, Robert Arlinghaus
No abstract text is available yet for this article.
October 20, 2021: Movement Ecology
#23
JOURNAL ARTICLE
Erin E Cook, Jill Davis, Rubeen Israni, Fan Mu, Keith A Betts, Deborah Anzalone, Lei Yin, Harold Szerlip, Gabriel I Uwaifo, Vivian Fonseca, Eric Q Wu
INTRODUCTION: Although hyperkalemia and metabolic acidosis often co-occur in patients with chronic kidney disease (CKD), the prevalence of metabolic acidosis among patients with CKD and hyperkalemia is understudied. Therefore, we used medical record data from the Research Action for Health Network to estimate this prevalence. METHODS: Adult patients with CKD stage 3-5, ≥ 1 outpatient potassium value > 5.0 mEq/l, and ≥ 1 outpatient bicarbonate value available were identified...
September 1, 2021: Advances in Therapy
#24
JOURNAL ARTICLE
Alexandra C Sietsma, Jill M Brennan-Cook, Lawrence T Malak, Vanessa L Lauzon
Patients suffering from mental illness are often less likely to engage in treatment at an outpatient level. Lack of communication and coordination of care between providers has negative results for the health system and the patient. Improved communication has shown improved satisfaction of providers in health care. Using prior research, an electronic reminder and standardized documentation of communication was added to the health system's electronic health record. The aim of this quality improvement (QI) project was to compare pre-/postintervention communication and satisfaction between emergency department and outpatient psychiatric providers...
July 2021: Advanced Emergency Nursing Journal
#25
JOURNAL ARTICLE
Mary A Majumder, Matthew L Blank, Janis Geary, Juli M Bollinger, Christi J Guerrini, Jill Oliver Robinson, Isabel Canfield, Robert Cook-Deegan, Amy L McGuire
Understanding the clinical significance of variants associated with hereditary cancer risk requires access to a pooled data resource or network of resources-a "cancer gene variant commons"-incorporating representative, well-characterized genetic data, metadata, and, for some purposes, pathways to case-level data. Several initiatives have invested significant resources into collecting and sharing cancer gene variant data, but further progress hinges on identifying and addressing unresolved policy issues. This commentary provides insights from a modified policy Delphi process involving experts from a range of stakeholder groups involved in the data-sharing ecosystem...
July 8, 2021: Journal of Personalized Medicine
#26
JOURNAL ARTICLE
Jeffrey P Jacobs, Rodney C G Franklin, Marie J Béland, Diane E Spicer, Steven D Colan, Henry L Walters, Frédérique Bailliard, Lucile Houyel, James D St Louis, Leo Lopez, Vera D Aiello, J William Gaynor, Otto N Krogmann, Hiromi Kurosawa, Bohdan J Maruszewski, Giovanni Stellin, Paul Morris Weinberg, Marshall Lewis Jacobs, Jeffrey R Boris, Meryl S Cohen, Allen D Everett, Jorge M Giroud, Kristine J Guleserian, Marina L Hughes, Amy L Juraszek, Stephen P Seslar, Charles W Shepard, Shubhika Srivastava, Andrew C Cook, Adrian Crucean, Lazaro E Hernandez, Rohit S Loomba, Lindsay S Rogers, Stephen P Sanders, Jill J Savla, Elif Seda Selamet Tierney, Justin T Tretter, Lianyi Wang, Martin J Elliott, Constantine Mavroudis, Christo I Tchervenkov
Substantial progress has been made in the standardization of nomenclature for paediatric and congenital cardiac care. In 1936, Maude Abbott published her Atlas of Congenital Cardiac Disease, which was the first formal attempt to classify congenital heart disease. The International Paediatric and Congenital Cardiac Code (IPCCC) is now utilized worldwide and has most recently become the paediatric and congenital cardiac component of the Eleventh Revision of the International Classification of Diseases (ICD-11)...
July 2021: Cardiology in the Young
#27
REVIEW
Robert J Lennox, Samuel Westrelin, Allan T Souza, Marek Šmejkal, Milan Říha, Marie Prchalová, Ran Nathan, Barbara Koeck, Shaun Killen, Ivan Jarić, Karl Gjelland, Jack Hollins, Gustav Hellstrom, Henry Hansen, Steven J Cooke, David Boukal, Jill L Brooks, Tomas Brodin, Henrik Baktoft, Timo Adam, Robert Arlinghaus
Movement ecology is increasingly relying on experimental approaches and hypothesis testing to reveal how, when, where, why, and which animals move. Movement of megafauna is inherently interesting but many of the fundamental questions of movement ecology can be efficiently tested in study systems with high degrees of control. Lakes can be seen as microcosms for studying ecological processes and the use of high-resolution positioning systems to triangulate exact coordinates of fish, along with sensors that relay information about depth, temperature, acceleration, predation, and more, can be used to answer some of movement ecology's most pressing questions...
July 28, 2021: Movement Ecology
#28
JOURNAL ARTICLE
Jeffrey P Jacobs, Rodney C G Franklin, Marie J Béland, Diane E Spicer, Steven D Colan, Henry L Walters, Frédérique Bailliard, Lucile Houyel, James D St Louis, Leo Lopez, Vera D Aiello, J William Gaynor, Otto N Krogmann, Hiromi Kurosawa, Bohdan J Maruszewski, Giovanni Stellin, Paul Morris Weinberg, Marshall Lewis Jacobs, Jeffrey R Boris, Meryl S Cohen, Allen D Everett, Jorge M Giroud, Kristine J Guleserian, Marina L Hughes, Amy L Juraszek, Stephen P Seslar, Charles W Shepard, Shubhika Srivastava, Andrew C Cook, Adrian Crucean, Lazaro E Hernandez, Rohit S Loomba, Lindsay S Rogers, Stephen P Sanders, Jill J Savla, Elif Seda Selamet Tierney, Justin T Tretter, Lianyi Wang, Martin J Elliott, Constantine Mavroudis, Christo I Tchervenkov
Substantial progress has been made in the standardization of nomenclature for paediatric and congenital cardiac care. In 1936, Maude Abbott published her Atlas of Congenital Cardiac Disease, which was the first formal attempt to classify congenital heart disease. The International Paediatric and Congenital Cardiac Code ( IPCCC ) is now utilized worldwide and has most recently become the paediatric and congenital cardiac component of the Eleventh Revision of the International Classification of Diseases (ICD-11)...
September 2021: World Journal for Pediatric & Congenital Heart Surgery
#29
JOURNAL ARTICLE
Jill Davis, Rubeen Israni, Fan Mu, Erin E Cook, Harold Szerlip, Gabriel Uwaifo, Vivian Fonseca, Keith A Betts
OBJECTIVES: Patients with hyperkalemia are commonly treated in the inpatient setting; however, real-world evidence is limited. The purpose of this study was to describe the inpatient management and post-discharge outcomes among patients with hyperkalemia. METHODS: Electronic medical record data (2012-2018) were used to analyze US adult patients with an inpatient stay with hyperkalemia (≥1 potassium value >5.0mEq/L). Patient characteristics, treatments, and monitoring six months prior to and during the inpatient stay, and hyperkalemia recurrence and inpatient readmissions post-discharge were summarized and compared among patients with mild (>5...
May 26, 2021: Hospital Practice (Minneapolis)
#30
JOURNAL ARTICLE
Jason Rogers, Graeme Jones, Jill L Cook, Karen Wills, Aroub Lahham, Tania M Winzenberg
OBJECTIVE: To determine the independent associations of potential clinical, symptom, physical activity, and psychological factors with chronic plantar heel pain. DESIGN: Case-control. METHODS: We investigated associations by comparing 220 participants with chronic (more than 3 months in duration) plantar heel pain to 100 age- and sex-matched controls, who were recruited randomly from the electoral roll. Exposures measured were waist girth, body mass index, body composition, clinical measures of foot and leg function, physical activity via accelerometry, depression and pain catastrophizing, symptoms of prolonged morning stiffness anywhere in the body, and multisite pain...
September 2021: Journal of Orthopaedic and Sports Physical Therapy
#31
JOURNAL ARTICLE
Sean Iain Docking, Ebonie Rio, Michael Alan Girdwood, Madeline Claire Hannington, Jill L Cook, Adam G Culvenor
OBJECTIVE: To estimate the pooled prevalence of, and factors associated with, the presence of patellar tendon abnormalities observed on imaging in people without symptoms. DESIGN: Systematic review with stratified meta-analysis and meta-regression. LITERATURE SEARCH: We searched EMBASE, Scopus, MEDLINE, CINAHL, SPORTDiscus, and Web of Science from 1980 to August 2020. STUDY SELECTION CRITERIA: We included studies that reported the prevalence of asymptomatic patellar tendon abnormalities on imaging...
March 28, 2021: Journal of Orthopaedic and Sports Physical Therapy
#32
JOURNAL ARTICLE
Sean Iain Docking, Harvi F Hart, Ebonie Rio, Madeline Claire Hannington, Jill L Cook, Adam G Culvenor
OBJECTIVE: To estimate the prevalence of, and factors associated with, Achilles tendon abnormalities observed on imaging in asymptomatic individuals. DESIGN: Systematic review with stratified meta-analysis and meta-regression. LITERATURE SEARCH: Embase, Scopus, MEDLINE, CINAHL, SPORTDiscus, and Web of Science were searched from 1980 to August 2020. STUDY SELECTION CRITERIA: We included studies that reported the prevalence of Achilles tendon abnormalities, observed with any imaging modality, in an asymptomatic population...
May 2021: Journal of Orthopaedic and Sports Physical Therapy
#33
JOURNAL ARTICLE
Aidan T Hanrath, Ina Schim van der Loeff, Dennis W Lendrem, Kenneth F Baker, David A Price, Peter McDowall, Kiera McDowall, Susan Cook, Peter Towns, Ulrich Schwab, Adam Evans, Jill Dixon, Jennifer Collins, Shirelle Burton-Fanning, David Saunders, Jayne Harwood, Julie Samuel, Matthias L Schmid, Lucia Pareja-Cebrian, Ewan Hunter, Elizabeth Murphy, Yusri Taha, Brendan A I Payne, Christopher J A Duncan
Healthcare workers (HCWs) are known to be at increased risk of infection with SARS-CoV-2, although whether these risks are equal across all roles is uncertain. Here we report a retrospective analysis of a large real-world dataset obtained from 10 March to 6 July 2020 in an NHS Foundation Trust in England with 17,126 employees. 3,338 HCWs underwent symptomatic PCR testing (14.4% positive, 2.8% of all staff) and 11,103 HCWs underwent serological testing for SARS-CoV-2 IgG (8.4% positive, 5.5% of all staff). Seropositivity was lower than other hospital settings in England but higher than community estimates...
2021: Frontiers in Medicine
#34
JOURNAL ARTICLE
Thomas A Werfel, Donna J Hicks, Bushra Rahman, Wendy E Bindeman, Matthew T Duvernay, Jae G Maeng, Heidi Hamm, Robert R Lavieri, Meghan M Joly, Jill M Pulley, David L Elion, Dana M Brantley-Sieders, Rebecca S Cook
While new drug discoveries are revolutionizing cancer treatments, repurposing existing drugs would accelerate the timeline and lower the cost for bringing treatments to cancer patients. Our goal was to repurpose CPI211, a potent and selective antagonist of the thromboxane A2-prostanoid receptor (TPr), a G-protein coupled receptor that regulates coagulation, blood pressure, and cardiovascular homeostasis. To identify potential new clinical indications for CPI211, we performed a Phenome Wide Association Study (PheWAS) of the gene encoding TPr, TBXA2R, using robust de-identified health records and matched genomic data from >29,000 patients...
October 8, 2020: Molecular Cancer Therapeutics
#35
JOURNAL ARTICLE
Breanne E Kunstler, Jill L Cook, Nicole Freene, Caroline F Finch, Joanne L Kemp, Paul D OʼHalloran, James E Gaida
No abstract text is available yet for this article.
July 2020: Clinical Journal of Sport Medicine
#36
JOURNAL ARTICLE
Jenni Ilomäki, J Simon Bell, Adrienne Y L Chan, Anna-Maija Tolppanen, Hao Luo, Li Wei, Edward Chia-Cheng Lai, Ju-Young Shin, Giorgia De Paoli, Romin Pajouheshnia, Frederick K Ho, Lorenna Reynolds, Kui Kai Lau, Stephen Crystal, Wallis C Y Lau, Kenneth K C Man, Ruth Brauer, Esther W Chan, Chin-Yao Shen, Ju Hwan Kim, Terry Y S Lum, Sirpa Hartikainen, Marjaana Koponen, Evelien Rooke, Marloes Bazelier, Olaf Klungel, Soko Setoguchi, Jill P Pell, Sharon Cook, Ian C K Wong
Neurological and psychiatric (mental health) disorders have a large impact on health burden globally. Cognitive disorders (including dementia) and stroke are leading causes of disability. Mental health disorders, including depression, contribute up to one-third of total years lived with disability. The Neurological and mental health Global Epidemiology Network (NeuroGEN) is an international multi-database network that harnesses administrative and electronic medical records from Australia, Asia, Europe and North America...
June 22, 2020: CNS Drugs
#37
JOURNAL ARTICLE
Rachel C Brierley, Daisy Gaunt, Chris Metcalfe, Jane M Blazeby, Natalie S Blencowe, Marcus Jepson, Richard G Berrisford, Kerry N L Avery, William Hollingworth, Caoimhe T Rice, Aida Moure-Fernandez, Newton Wong, Joanna Nicklin, Anni Skilton, Alex Boddy, James P Byrne, Tim Underwood, Ravi Vohra, James A Catton, Kish Pursnani, Rachel Melhado, Bilal Alkhaffaf, Richard Krysztopik, Peter Lamb, Lucy Culliford, Chris Rogers, Benjamin Howes, Katy Chalmers, Sian Cousins, Jackie Elliott, Jenny Donovan, Rachael Heys, Robin A Wickens, Paul Wilkerson, Andrew Hollowood, Christopher Streets, Dan Titcomb, Martyn Lee Humphreys, Tim Wheatley, Grant Sanders, Arun Ariyarathenam, Jamie Kelly, Fergus Noble, Graeme Couper, Richard J E Skipworth, Chris Deans, Sukhbir Ubhi, Robert Williams, David Bowrey, David Exon, Paul Turner, Vinutha Daya Shetty, Ram Chaparala, Khurshid Akhtar, Naheed Farooq, Simon L Parsons, Neil T Welch, Rebecca J Houlihan, Joanne Smith, Rachel Schranz, Nicola Rea, Jill Cooke, Alexandra Williams, Carolyn Hindmarsh, Sally Maitland, Lucy Howie, Christopher Paul Barham
INTRODUCTION: Surgery (oesophagectomy), with neoadjuvant chemo(radio)therapy, is the main curative treatment for patients with oesophageal cancer. Several surgical approaches can be used to remove an oesophageal tumour. The Ivor Lewis (two-phase procedure) is usually used in the UK. This can be performed as an open oesophagectomy (OO), a laparoscopically assisted oesophagectomy (LAO) or a totally minimally invasive oesophagectomy (TMIO). All three are performed in the National Health Service, with LAO and OO the most common...
November 19, 2019: BMJ Open
#38
JOURNAL ARTICLE
Kelly M Houck, Enrique Terán, Juan Ochoa, Gyssell N Zapata, Ana M Gomez, Rafael Parra, Denise Dvorquez, Jill R Stewart, Margaret E Bentley, Amanda L Thompson
OBJECTIVES: The Galápagos provides an important setting to investigate the health impacts of a new drinking water treatment plant (DWTP) in a limited resource environment. We examine how household perceptions and practices affect the relationship between water quality and infections before and after DWTP. METHODS: Ethnographic data and self-reported infections were collected from 121 mothers and 168 children ages 2 to 10 from Isla San Cristóbal. Household tap water samples were tested for levels of fecal contamination...
November 19, 2019: American Journal of Human Biology: the Official Journal of the Human Biology Council
#39
JOURNAL ARTICLE
Bill Vicenzino, Robert-Jan de Vos, Hakan Alfredson, Roald Bahr, Jill L Cook, Brooke K Coombes, Siu Ngor Fu, Karin Gravare Silbernagel, Alison Grimaldi, Jeremy S Lewis, Nicola Maffulli, S P Magnusson, Peter Malliaras, Sean Mc Auliffe, Edwin H G Oei, Craig Purdam, Jonathan D Rees, Ebonie Kendra Rio, Alex Scott, Cathy Speed, Inge van den Akker-Scheek, Adam Weir, Jennifer Moriatis Wolf, Johannes Zwerver
BACKGROUND: The absence of any agreed-upon tendon health-related domains hampers advances in clinical tendinopathy research. This void means that researchers report a very wide range of outcome measures inconsistently. As a result, substantial synthesis/meta-analysis of tendon research findings is almost futile despite researchers publishing busily. We aimed to determine options for, and then define, core health-related domains for tendinopathy. METHODS: We conducted a Delphi study of healthcare professionals (HCP) and patients in a three-stage process...
April 2020: British Journal of Sports Medicine
#40
JOURNAL ARTICLE
Ebonie Kendra Rio, Sean Mc Auliffe, Irene Kuipers, Michael Girdwood, Hakan Alfredson, Roald Bahr, Jill L Cook, Brooke Coombes, Siu Ngor Fu, Alison Grimaldi, Robert-Jan de Vos, Jeremy S Lewis, Nicola Maffulli, Peter Malliaras, S P Magnusson, Edwin H G Oei, Craig Robert Purdam, Jonathan D Rees, Alex Scott, Karin Gravare Silbernagel, Cathy Speed, Inge van den Akker-Scheek, Bill T Vicenzino, Adam Weir, Jennifer Moriatis Wolf, Johannes Zwerver
We aimed to establish consensus for reporting recommendations relating to participant characteristics in tendon research. A scoping literature review of tendinopathy studies (Achilles, patellar, hamstring, gluteal and elbow) was followed by an online survey and face-to-face consensus meeting with expert healthcare professionals (HCPs) at the International Scientific Tendon Symposium, Groningen 2018. We reviewed 263 papers to form statements for consensus and invited 30 HCPs from different disciplines and geographical locations; 28 completed the survey and 15 attended the meeting...
June 2020: British Journal of Sports Medicine
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