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Jill L Cook

Suzi Edwards, Hiram C Brooke, Jill L Cook
OBJECTIVES: This study aimed to explore the differences in the magnitude of movement variability and strategies utilized during an unanticipated cut task between players with and without a history of groin pain. DESIGN: Cross-sectional design. SETTING: Biomechanics laboratory. PARTICIANTS: Male Australian football players with (HISTORY; n = 7) or without (CONTROL; n = 10) a history of groin pain. OUTCOME MEASURES: Three-dimensional ground reaction forces (GRF) and kinematics were recorded during 10 successful trials of an unanticipated cut task, and isokinetic hip adduction and abduction strength...
July 22, 2016: Physical Therapy in Sport
Thomas C Hall, Dilraj K Bilku, Christopher P Neal, Jill Cooke, Helena L Fisk, Philip C Calder, Ashley R Dennison
BACKGROUND: Death from sepsis in the intensive therapy unit (ITU) is frequently preceded by the development of multiple organ failure as a result of uncontrolled inflammation. Treatment with omega-3 (n-3) fatty acids (FAs), principally eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), has been demonstrated to attenuate the effects of uncontrolled inflammation and may be clinically beneficial in reducing mortality from organ dysfunction. Fish oil (FO) is a source of EPA and DHA...
September 2016: Prostaglandins, Leukotrienes, and Essential Fatty Acids
Andrew R Nealon, Alex Kountouris, Jill L Cook
OBJECTIVES: To provide an overview of the published literature on epidemiology, pathomechanics and risk factors for side strain injury in sport, complemented by clinical perspectives of diagnosis and management strategies that are not covered in the literature. DESIGN: Narrative review METHODS: A review of the literature was completed with all studies on side strain up until October 2015 included. As the studies were unable to be synthesised the findings were placed in a clinical context...
August 28, 2016: Journal of Science and Medicine in Sport
Cylie M Williams, Elizabeth H Skinner, Alicia M James, Jill L Cook, Steven M McPhail, Terry P Haines
Comparative effectiveness research compares two active forms of treatment or usual care in comparison with usual care with an additional intervention element. These types of study are commonly conducted following a placebo or no active treatment trial. Research designs with a placebo or non-active treatment arm can be challenging for the clinician researcher when conducted within the healthcare environment with patients attending for treatment.A framework for conducting comparative effectiveness research is needed, particularly for interventions for which there are no strong regulatory requirements that must be met prior to their introduction into usual care...
2016: Trials
Suzi Edwards, Julie R Steele, Deirdre E McGhee, Craig R Purdam, Jill L Cook
This study aimed to explore how asymptomatic athletes with a patellar tendon abnormality (PTA), who are at high risk of developing patellar tendinopathy, alter their landing technique and net patellar tendon loads generated in response to fatigue. Seven asymptomatic players with a PTA performed five successful vertical stop-jump trials before and after a fatigue protocol. Fatigue protocol involved participants repeatedly performing sets of 30 submaximal jump exercises on a sledge apparatus followed by 30 s rest until the task failure criteria were reached...
May 31, 2016: Journal of Sports Sciences
Mariam Kayle, Jill Brennan-Cook, Brigit M Carter, Anne L Derouin, Susan G Silva, Paula Tanabe
Sickle cell disease (SCD) is a complex multisystem debilitating disease. Despite its complexity, health care providers who are not SCD experts receive little formal education on SCD. An open-access, educational website, "Emergency Department Sickle Cell Disease: Crisis Management and Beyond," was created to provide education about SCD to emergency department (ED) providers who are not SCD experts but who provide care for patients with SCD. Electronic surveys were used to conduct a formal evaluation of the accuracy and relevance of the website's content, as well as the effectiveness of the education modules in improving knowledge among health care providers...
April 2016: Advanced Emergency Nursing Journal
Raman Sharma, Ghaith Al Jayoussi, Hayley E Tyrer, Joanne Gamble, Laura Hayward, Ana F Guimaraes, Jill Davies, David Waterhouse, Darren A N Cook, Laura J Myhill, Rachel H Clare, Andrew Cassidy, Andrew Steven, Kelly L Johnston, Louise Ford, Joseph D Turner, Stephen A Ward, Mark J Taylor
Lymphatic filariasis and onchocerciasis are parasitic helminth diseases, which cause severe morbidities such as elephantiasis, skin disease and blindness, presenting a major public health burden in endemic communities. The anti-Wolbachia consortium (A·WOL: has identified a number of registered antibiotics that target the endosymbiotic bacterium, Wolbachia, delivering macrofilaricidal activity. Here we use pharmacokinetics/pharmacodynamics (PK/PD) analysis to rationally develop an anti-Wolbachia chemotherapy by linking drug exposure to pharmacological effect...
2016: Scientific Reports
James E Gaida, Håkan Alfredson, Sture Forsgren, Jill L Cook
BACKGROUND: Achilles tendinopathy is a painful musculoskeletal condition that is common among athletes, and which limits training capacity and competitive performance. The lack of biomarkers for tendinopathy limits research into risk factors and also the evaluation of new treatments. Cytokines and growth factors involved in regulating the response of tendon cells to mechanical load have potential as biomarkers for tendinopathy. METHODS: This case-control study compared serum concentration of cytokines and growth factors (TNF-α, IL-1β, bFGF, PDFG-BB, IFN-γ, VEGF) between individuals with chronic Achilles tendinopathy and controls...
2016: BMC Sports Science, Medicine and Rehabilitation
Mathijs van Ark, Jill L Cook, Sean I Docking, Johannes Zwerver, James E Gaida, Inge van den Akker-Scheek, Ebonie Rio
OBJECTIVES: Many athletes with patellar tendinopathy participate in sports with symptoms during or after activities. Current treatments do not decrease pain in-season; eccentric exercises in-season result in an increase in pain. This study examined if isometric and isotonic exercises relieved pain in competing athletes with patellar tendinopathy. DESIGN: Randomised clinical trial. METHODS: Jumping athletes with patellar tendinopathy playing at least three times per week participated in this study...
September 2016: Journal of Science and Medicine in Sport
Tom A Ranger, Andrea M Y Wong, Jill L Cook, Jamie E Gaida
BACKGROUND: Musculoskeletal symptoms limit adherence to exercise interventions for individuals with type 2 diabetes. People with diabetes may be susceptible to tendinopathy due to chronically elevated blood glucose levels. Therefore, we aimed to investigate this potential association by systematically reviewing and meta-analysing case-control, cross-sectional, and studies that considered both of these conditions. METHODS: Nine medical databases and hand searching methods were used without year limits to identify all relevant English language articles that considered diabetes and tendinopathy...
August 2016: British Journal of Sports Medicine
Andrea M Y Wong, Sean I Docking, Jill L Cook, James E Gaida
BACKGROUND: Achilles tendon structure deteriorates 2-days after maximal loading in elite athletes. The load-response behaviour of tendons may be altered in type 1 diabetes mellitus (T1DM) as hyperglycaemia accelerates collagen cross-linking. This study compared Achilles tendon load-response in participants with T1DM and controls. METHODS: Achilles tendon structure was quantified at day-0, day-2 and day-4 after a 10 km run. Ultrasound tissue characterisation (UTC) measures tendon structural integrity by classifying pixels as echo-type I, II, III or IV...
2015: BMC Musculoskeletal Disorders
Benjamin J Tilley, Jill L Cook, Sean I Docking, James E Gaida
BACKGROUND: Tendon pain occurs in individuals with extreme cholesterol levels (familial hypercholesterolaemia). It is unclear whether the association with tendon pain is strong with less extreme elevations of cholesterol. OBJECTIVE: To determine whether lipid levels are associated with abnormal tendon structure or the presence of tendon pain. METHODS: We conducted a systematic review and meta-analysis. Relevant articles were found through an electronic search of 6 medical databases-MEDLINE, Cochrane, AMED, EMBASE, Web of Science and Scopus...
December 2015: British Journal of Sports Medicine
Adam G Culvenor, Natalie J Collins, Ali Guermazi, Jill L Cook, Bill Vicenzino, Timothy S Whitehead, Hayden G Morris, Kay M Crossley
OBJECTIVE: To determine whether the presence of magnetic resonance imaging (MRI) osteoarthritis (OA) features in the patellofemoral or tibiofemoral joint (i.e., bone marrow lesions, cartilage lesions, and osteophytes) and/or functional impairments, 1 year following anterior cruciate ligament reconstruction (ACLR), can predict Knee Injury and Osteoarthritis Outcome Score (KOOS) at 3 years. METHODS: A total of 93 participants (56 [60%] men, mean ± SD age 29 ± 9 years) who had undergone MRI examination and functional testing at 1-year post-ACLR, completed the KOOS at 3 years postsurgery...
June 2016: Arthritis Care & Research
Massimo Sartelli, Mark A Malangoni, Fikri M Abu-Zidan, Ewen A Griffiths, Stefano Di Bella, Lynne V McFarland, Ian Eltringham, Vishal G Shelat, George C Velmahos, Ciarán P Kelly, Sahil Khanna, Zaid M Abdelsattar, Layan Alrahmani, Luca Ansaloni, Goran Augustin, Miklosh Bala, Frédéric Barbut, Offir Ben-Ishay, Aneel Bhangu, Walter L Biffl, Stephen M Brecher, Adrián Camacho-Ortiz, Miguel A Caínzos, Laura A Canterbury, Fausto Catena, Shirley Chan, Jill R Cherry-Bukowiec, Jesse Clanton, Federico Coccolini, Maria Elena Cocuz, Raul Coimbra, Charles H Cook, Yunfeng Cui, Jacek Czepiel, Koray Das, Zaza Demetrashvili, Isidoro Di Carlo, Salomone Di Saverio, Irina Magdalena Dumitru, Catherine Eckert, Christian Eckmann, Edward H Eiland, Mushira Abdulaziz Enani, Mario Faro, Paula Ferrada, Joseph Derek Forrester, Gustavo P Fraga, Jean Louis Frossard, Rita Galeiras, Wagih Ghnnam, Carlos Augusto Gomes, Venkata Gorrepati, Mohamed Hassan Ahmed, Torsten Herzog, Felicia Humphrey, Jae Il Kim, Arda Isik, Rao Ivatury, Yeong Yeh Lee, Paul Juang, Luis Furuya-Kanamori, Aleksandar Karamarkovic, Peter K Kim, Yoram Kluger, Wen Chien Ko, Francis D LaBarbera, Jae Gil Lee, Ari Leppaniemi, Varut Lohsiriwat, Sanjay Marwah, John E Mazuski, Gokhan Metan, Ernest E Moore, Frederick Alan Moore, Carl Erik Nord, Carlos A Ordoñez, Gerson Alves Pereira Júnior, Nicola Petrosillo, Francisco Portela, Basant K Puri, Arnab Ray, Mansoor Raza, Miran Rems, Boris E Sakakushev, Gabriele Sganga, Patrizia Spigaglia, David B Stewart, Pierre Tattevin, Jean Francois Timsit, Kathleen B To, Cristian Tranà, Waldemar Uhl, Libor Urbánek, Harry van Goor, Angela Vassallo, Jean Ralph Zahar, Emanuele Caproli, Pierluigi Viale
In the last two decades there have been dramatic changes in the epidemiology of Clostridium difficile infection (CDI), with increases in incidence and severity of disease in many countries worldwide. The incidence of CDI has also increased in surgical patients. Optimization of management of C difficile, has therefore become increasingly urgent. An international multidisciplinary panel of experts prepared evidenced-based World Society of Emergency Surgery (WSES) guidelines for management of CDI in surgical patients...
2015: World Journal of Emergency Surgery: WJES
Omar S Akbari, Hugo J Bellen, Ethan Bier, Simon L Bullock, Austin Burt, George M Church, Kevin R Cook, Peter Duchek, Owain R Edwards, Kevin M Esvelt, Valentino M Gantz, Kent G Golic, Scott J Gratz, Melissa M Harrison, Keith R Hayes, Anthony A James, Thomas C Kaufman, Juergen Knoblich, Harmit S Malik, Kathy A Matthews, Kate M O'Connor-Giles, Annette L Parks, Norbert Perrimon, Fillip Port, Steven Russell, Ryu Ueda, Jill Wildonger
No abstract text is available yet for this article.
August 28, 2015: Science
Adam G Culvenor, Natalie J Collins, Bill Vicenzino, Jill L Cook, Timothy S Whitehead, Hayden G Morris, Kay M Crossley
OBJECTIVES: Patellofemoral pain is a frequent and troublesome complication following anterior cruciate ligament reconstruction (ACLR), irrespective of graft source. Yet, little is known about the factors associated with patellofemoral pain following hamstring-tendon ACLR. DESIGN: Retrospective analysis of potential patellofemoral pain predictors, and cross-sectional analysis of possible patellofemoral pain consequences. METHODS: Potential predictors (pre-injury patellofemoral pain and activity level, concomitant patellofemoral cartilage damage and meniscectomy, age, sex, and surgical delay) and consequences (hopping performance, quality of life, kinesiophobia, and return to sport rates and attitudes) of patellofemoral pain 12 months following hamstring-tendon ACLR were assessed in 110 participants using univariate and multivariate analyses...
July 2016: Journal of Science and Medicine in Sport
Timothy J Hohman, Jessica N Cooke-Bailey, Christiane Reitz, Gyungah Jun, Adam Naj, Gary W Beecham, Zhi Liu, Regina M Carney, Jeffrey M Vance, Michael L Cuccaro, Ruchita Rajbhandary, Badri Narayan Vardarajan, Li-San Wang, Otto Valladares, Chiao-Feng Lin, Eric B Larson, Neill R Graff-Radford, Denis Evans, Philip L De Jager, Paul K Crane, Joseph D Buxbaum, Jill R Murrell, Towfique Raj, Nilufer Ertekin-Taner, Mark W Logue, Clinton T Baldwin, Robert C Green, Lisa L Barnes, Laura B Cantwell, M Daniele Fallin, Rodney C P Go, Patrick Griffith, Thomas O Obisesan, Jennifer J Manly, Kathryn L Lunetta, M Ilyas Kamboh, Oscar L Lopez, David A Bennett, John Hardy, Hugh C Hendrie, Kathleen S Hall, Alison M Goate, Rosalyn Lang, Goldie S Byrd, Walter A Kukull, Tatiana M Foroud, Lindsay A Farrer, Eden R Martin, Margaret A Pericak-Vance, Gerard D Schellenberg, Richard Mayeux, Jonathan L Haines, Tricia A Thornton-Wells
INTRODUCTION: African-American (AA) individuals have a higher risk for late-onset Alzheimer's disease (LOAD) than Americans of primarily European ancestry (EA). Recently, the largest genome-wide association study in AAs to date confirmed that six of the Alzheimer's disease (AD)-related genetic variants originally discovered in EA cohorts are also risk variants in AA; however, the risk attributable to many of the loci (e.g., APOE, ABCA7) differed substantially from previous studies in EA...
March 2016: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
Susan J Mayes, Paula H Baird-Colt, Jill L Cook
Atrophy of the stabilizing muscles of the hip, such as quadratus femoris (QF), may predispose the hip joint to dysfunction. Ultrasound imaging (USI) has been shown to be a valid and reliable method of measuring the size of several hip muscles, but QF size has not been investigated. The objectives of this study were to establish the criterion validity of USI against the "gold standard" magnetic resonance imaging (MRI) for measuring the QF cross-sectional area (CSA) and to investigate intra-rater reliability of USI...
March 2015: Journal of Dance Medicine & Science
Adam G Culvenor, Natalie J Collins, Ali Guermazi, Jill L Cook, Bill Vicenzino, Karim M Khan, Naomi Beck, Janneke van Leeuwen, Kay M Crossley
OBJECTIVE: To determine the prevalence and factors associated with knee osteoarthritis (OA) defined by magnetic resonance imaging (MRI) and specific OA features on MRI 1 year after anterior cruciate ligament reconstruction (ACLR). METHODS: Isotropic 3.0T MRI scans were obtained for 111 participants (71 men; mean ± SD age 30 ± 8 years) 1 year after ACLR as well as for 20 age-, sex-, and activity level-matched uninjured controls. The MRI OA Knee Score was used to score specific OA features...
April 2015: Arthritis & Rheumatology
Tom A Ranger, Wendy M Braybon, Craig R Purdam, Jill L Cook
CONTEXT: Lateral epicondylalgia, pain at the lateral elbow, is commonly associated with extensor carpi radialis brevis tendinopathy. The radial head, which abuts the extensor tendons and is elliptical in shape, may affect the extensor tendons during pronation of the forearm. Cadaverous studies have shown that the radial head may act as a cam in pronation, to offer a mechanical advantage to the common extensor tendon and to mitigate load on the origin of the extensor carpi radialis brevis tendon...
February 2015: Journal of Sport Rehabilitation
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