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Jill L Cook

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https://www.readbyqxmd.com/read/29093676/bioinspired-technologies-to-connect-musculoskeletal-mechanobiology-to-the-person-for-training-and-rehabilitation
#1
REVIEW
Claudio Pizzolato, David G Lloyd, Rod S Barrett, Jill L Cook, Ming H Zheng, Thor F Besier, David J Saxby
Musculoskeletal tissues respond to optimal mechanical signals (e.g., strains) through anabolic adaptations, while mechanical signals above and below optimal levels cause tissue catabolism. If an individual's physical behavior could be altered to generate optimal mechanical signaling to musculoskeletal tissues, then targeted strengthening and/or repair would be possible. We propose new bioinspired technologies to provide real-time biofeedback of relevant mechanical signals to guide training and rehabilitation...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/29078351/albendazole-and-antibiotics-synergize-to-deliver-short-course-anti-wolbachia-curative-treatments-in-preclinical-models-of-filariasis
#2
Joseph D Turner, Raman Sharma, Ghaith Al Jayoussi, Hayley E Tyrer, Joanne Gamble, Laura Hayward, Richard S Priestley, Emma A Murphy, Jill Davies, David Waterhouse, Darren A N Cook, Rachel H Clare, Andrew Cassidy, Andrew Steven, Kelly L Johnston, John McCall, Louise Ford, Janet Hemingway, Stephen A Ward, Mark J Taylor
Elimination of filariasis requires a macrofilaricide treatment that can be delivered within a 7-day period. Here we have identified a synergy between the anthelmintic albendazole (ABZ) and drugs depleting the filarial endosymbiont Wolbachia, a proven macrofilaricide target, which reduces treatment from several weeks to 7 days in preclinical models. ABZ had negligible effects on Wolbachia but synergized with minocycline or rifampicin (RIF) to deplete symbionts, block embryogenesis, and stop microfilariae production...
October 23, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29064864/physiotherapist-led-physical-activity-interventions-are-efficacious-at-increasing-physical-activity-levels-a-systematic-review-and-meta-analysis
#3
Breanne E Kunstler, Jill L Cook, Nicole Freene, Caroline F Finch, Joanne L Kemp, Paul D OʼHalloran, James E Gaida
OBJECTIVE: Physical activity (PA) interventions to address noncommunicable disease (NCD) risk are commonly delivered in private practice and outpatient physiotherapy settings. This study reviewed the efficacy of physiotherapist-led physical activity (PLPA) interventions at improving PA levels. DATA SOURCES: Twelve databases were searched using terms related to both physiotherapy and PA. English-language studies of all designs in adults were included. Meta-analyses were conducted separately for interventions measuring the following: (1) participants meeting recommended PA levels; (2) total PA at short- and long-term follow-up; and (3) total PA achieved after short and long PLPA interventions...
October 20, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29053419/enhanced-sanitation-standard-operating-procedures-have-limited-impact-on-listeria-monocytogenes-prevalence-in-retail-delis
#4
Andrea J Etter, Susan R Hammons, Sherry Roof, Courtenay Simmons, Tongyu Wu, Peter W Cook, Alex Katubig, Matthew J Stasiewicz, Emily Wright, Steven Warchocki, Jill Hollingworth, Hilary S Thesmar, Salam A Ibrahim, Martin Wiedmann, Haley F Oliver
In a recent longitudinal surveillance study in 30 U.S. retail delicatessens, 9.7% of environmental surfaces were positive for Listeria monocytogenes, and we found substantial evidence of persistence. In this study, we aimed to reduce the prevalence and persistence of L. monocytogenes in the retail deli environment by developing and implementing practical and feasible intervention strategies (i.e., sanitation standard operating procedures; SSOPs). These SSOPs were standardized across the 30 delis enrolled in this study...
October 20, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/29049607/dose-response-association-of-cd8-tumor-infiltrating-lymphocytes-and-survival-time-in-high-grade-serous-ovarian-cancer
#5
Ellen L Goode, Matthew S Block, Kimberly R Kalli, Robert A Vierkant, Wenqian Chen, Zachary C Fogarty, Aleksandra Gentry-Maharaj, Aleksandra Toloczko, Alexander Hein, Aliecia L Bouligny, Allan Jensen, Ana Osorio, Andreas D Hartkopf, Andy Ryan, Anita Chudecka-Glaz, Anthony M Magliocco, Arndt Hartmann, Audrey Y Jung, Bo Gao, Brenda Y Hernandez, Brooke L Fridley, Bryan M McCauley, Catherine J Kennedy, Chen Wang, Chloe Karpinskyj, Christiani B de Sousa, Daniel G Tiezzi, David L Wachter, Esther Herpel, Florin Andrei Taran, Francesmary Modugno, Gregg Nelson, Jan Lubinski, Janusz Menkiszak, Jennifer Alsop, Jenny Lester, Jesús García-Donas, Jill Nation, Jillian Hung, José Palacios, Joseph H Rothstein, Joseph L Kelley, Jurandyr M de Andrade, Luis Robles-Díaz, Maria P Intermaggio, Martin Widschwendter, Matthias W Beckmann, Matthias Ruebner, Mercedes Jimenez-Linan, Naveena Singh, Oleg Oszurek, Paul R Harnett, Peter F Rambau, Peter Sinn, Philipp Wagner, Prafull Ghatage, Raghwa Sharma, Robert P Edwards, Roberta B Ness, Sandra Orsulic, Sara Y Brucker, Sharon E Johnatty, Teri A Longacre, Ursula Eilber, Valerie McGuire, Weiva Sieh, Yanina Natanzon, Zheng Li, Alice S Whittemore, Anna deFazio, Annette Staebler, Beth Y Karlan, Blake Gilks, David D Bowtell, Estrid Høgdall, Francisco J Candido Dos Reis, Helen Steed, Ian G Campbell, Jacek Gronwald, Javier Benítez, Jennifer M Koziak, Jenny Chang-Claude, Kirsten B Moysich, Linda E Kelemen, Linda S Cook, Marc T Goodman, María José García, Peter A Fasching, Stefan Kommoss, Suha Deen, Susanne K Kjaer, Usha Menon, James D Brenton, Paul D P Pharoah, Georgia Chenevix-Trench, David G Huntsman, Stacey J Winham, Martin Köbel, Susan J Ramus
Importance: Cytotoxic CD8+ tumor-infiltrating lymphocytes (TILs) participate in immune control of epithelial ovarian cancer; however, little is known about prognostic patterns of CD8+ TILs by histotype and in relation to other clinical factors. Objective: To define the prognostic role of CD8+ TILs in epithelial ovarian cancer. Design, Setting, and Participants: This was a multicenter observational, prospective survival cohort study of the Ovarian Tumor Tissue Analysis Consortium...
October 12, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28886596/assessing-exposure-to-household-air-pollution-a-systematic-review-and-pooled-analysis-of-carbon-monoxide-as-a-surrogate-measure-of-particulate-matter
#6
REVIEW
Ellison Carter, Christina Norris, Kathie L Dionisio, Kalpana Balakrishnan, William Checkley, Maggie L Clark, Santu Ghosh, Darby W Jack, Patrick L Kinney, Julian D Marshall, Luke P Naeher, Jennifer L Peel, Sankar Sambandam, James J Schauer, Kirk R Smith, Blair J Wylie, Jill Baumgartner
BACKGROUND: Household air pollution from solid fuel burning is a leading contributor to disease burden globally. Fine particulate matter (PM2.5) is thought to be responsible for many of these health impacts. A co-pollutant, carbon monoxide (CO) has been widely used as a surrogate measure of PM2.5 in studies of household air pollution. OBJECTIVE: The goal was to evaluate the validity of exposure to CO as a surrogate of exposure to PM2.5 in studies of household air pollution and the consistency of the PM2...
July 28, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28742615/trunk-side-strain-has-a-high-incidence-in-first-class-cricket-fast-bowlers-in-australia-and-england
#7
Andrew R Nealon, Jill L Cook
OBJECTIVE: To investigate the past incidence of side strain injury and its associated factors in first-class cricket fast bowlers in Australia and England. DESIGN: Retrospective case series. SETTING: Professional cricket. PARTICIPANTS: Cricket fast bowlers who were professionally contracted full time at first-class level in Australia and England in 2011. All bowlers were male and aged 18 or older. A bowler was defined as a fast bowler if the wicketkeeper would take their stance back from the stumps...
July 21, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28640196/vitamin-d%C3%A2-and-25-hydroxyvitamin-d%C3%A2-content-of-retail-white-fish-and-eggs-in-australia
#8
Eleanor Dunlop, Judy Cunningham, Jill L Sherriff, Robyn M Lucas, Heather Greenfield, Jayashree Arcot, Norbert Strobel, Lucinda J Black
Dietary vitamin D may compensate for inadequate sun exposure; however, there have been few investigations into the vitamin D content of Australian foods. We measured vitamin D₃ and 25-hydroxyvitamin D₃ (25(OH)D₃) in four species of white fish (barramundi, basa, hoki and king dory), and chicken eggs (cage and free-range), purchased from five Australian cities. Samples included local, imported and wild-caught fish, and eggs of varying size from producers with a range of hen stocking densities. Raw and cooked samples were analysed using high performance liquid chromatography with photodiode array...
June 22, 2017: Nutrients
https://www.readbyqxmd.com/read/28500081/quadriceps-strengthening-with-and-without-blood-flow-restriction-in-the-treatment-of-patellofemoral-pain-a-double-blind-randomised-trial
#9
Lachlan Giles, Kate E Webster, Jodie McClelland, Jill L Cook
BACKGROUND: Quadriceps strengthening exercises are part of the treatment of patellofemoral pain (PFP), but the heavy resistance exercises may aggravate knee pain. Blood flow restriction (BFR) training may provide a low-load quadriceps strengthening method to treat PFP. METHODS: Seventy-nine participants were randomly allocated to a standardised quadriceps strengthening (standard) or low-load BFR. Both groups performed 8 weeks of leg press and leg extension, the standard group at 70% of 1 repetition maximum (1RM) and the BFR group at 30% of 1RM...
May 12, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28303006/short-course-high-dose-rifampicin-achieves-wolbachia-depletion-predictive-of-curative-outcomes-in-preclinical-models-of-lymphatic-filariasis-and-onchocerciasis
#10
Ghaith Aljayyoussi, Hayley E Tyrer, Louise Ford, Hanna Sjoberg, Nicolas Pionnier, David Waterhouse, Jill Davies, Joanne Gamble, Haelly Metugene, Darren A N Cook, Andrew Steven, Raman Sharma, Ana F Guimaraes, Rachel H Clare, Andrew Cassidy, Kelly L Johnston, Laura Myhill, Laura Hayward, Samuel Wanji, Joseph D Turner, Mark J Taylor, Stephen A Ward
Lymphatic filariasis (LF) and onchocerciasis are priority neglected tropical diseases targeted for elimination. The only safe drug treatment with substantial curative activity against the filarial nematodes responsible for LF (Brugia malayi, Wuchereria bancrofti) or onchocerciasis (Onchocerca volvulus) is doxycycline. The target of doxycycline is the essential endosymbiont, Wolbachia. Four to six weeks doxycycline therapy achieves >90% depletion of Wolbachia in worm tissues leading to blockade of embryogenesis, adult sterility and premature death 18-24 months post-treatment...
March 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28110492/what-are-the-determinants-of-food-security-among-regional-and-remote-western-australian-children
#11
Stephanie L Godrich, Christina R Davies, Jill Darby, Amanda Devine
OBJECTIVE: To explore how determinants of food security affect children in regional and remote Western Australia (WA), across food availability, access and utilisation dimensions. METHODS: The Determinants of Food Security framework guided the thematic analysis (using NVivo 10) of semi-structured interviews with 20 key informants. RESULTS: Food availability factors included availability, price, promotion, quality, location of outlets and variety...
January 22, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/27693099/distinct-cut-task-strategy-in-australian-football-players-with-a-history-of-groin-pain
#12
Suzi Edwards, Hiram C Brooke, Jill L Cook
OBJECTIVES: This study aimed to explore the differences in the magnitude of movement variability and strategies utilized during an unanticipated cut task between players with and without a history of groin pain. DESIGN: Cross-sectional design. SETTING: Biomechanics laboratory. PARTICIANTS: Male Australian football players with (HISTORY; n = 7) or without (CONTROL; n = 10) a history of groin pain. OUTCOME MEASURES: Three-dimensional ground reaction forces (GRF) and kinematics were recorded during 10 successful trials of an unanticipated cut task, and isokinetic hip adduction and abduction strength...
January 2017: Physical Therapy in Sport
https://www.readbyqxmd.com/read/27637335/the-impact-of-an-omega-3-fatty-acid-rich-lipid-emulsion-on-fatty-acid-profiles-in-critically-ill-septic-patients
#13
Thomas C Hall, Dilraj K Bilku, Christopher P Neal, Jill Cooke, Helena L Fisk, Philip C Calder, Ashley R Dennison
BACKGROUND: Death from sepsis in the intensive therapy unit (ITU) is frequently preceded by the development of multiple organ failure as a result of uncontrolled inflammation. Treatment with omega-3 (n-3) fatty acids (FAs), principally eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), has been demonstrated to attenuate the effects of uncontrolled inflammation and may be clinically beneficial in reducing mortality from organ dysfunction. Fish oil (FO) is a source of EPA and DHA...
September 2016: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/27616432/side-strain-in-sport-a-narrative-review-of-pathomechanics-diagnosis-imaging-and-management-for-the-clinician
#14
REVIEW
Andrew R Nealon, Alex Kountouris, Jill L Cook
OBJECTIVES: To provide an overview of the published literature on epidemiology, pathomechanics and risk factors for side strain injury in sport, complemented by clinical perspectives of diagnosis and management strategies that are not covered in the literature. DESIGN: Narrative review METHODS: A review of the literature was completed with all studies on side strain up until October 2015 included. As the studies were unable to be synthesised the findings were placed in a clinical context...
March 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/27530915/comparative-effectiveness-research-for-the-clinician-researcher-a-framework-for-making-a-methodological-design-choice
#15
EDITORIAL
Cylie M Williams, Elizabeth H Skinner, Alicia M James, Jill L Cook, Steven M McPhail, Terry P Haines
Comparative effectiveness research compares two active forms of treatment or usual care in comparison with usual care with an additional intervention element. These types of study are commonly conducted following a placebo or no active treatment trial. Research designs with a placebo or non-active treatment arm can be challenging for the clinician researcher when conducted within the healthcare environment with patients attending for treatment.A framework for conducting comparative effectiveness research is needed, particularly for interventions for which there are no strong regulatory requirements that must be met prior to their introduction into usual care...
2016: Trials
https://www.readbyqxmd.com/read/27241475/asymptomatic-players-with-a-patellar-tendon-abnormality-do-not-adapt-their-landing-mechanics-when-fatigued
#16
Suzi Edwards, Julie R Steele, Deirdre E McGhee, Craig R Purdam, Jill L Cook
This study aimed to explore how asymptomatic athletes with a patellar tendon abnormality (PTA), who are at high risk of developing patellar tendinopathy, alter their landing technique and net patellar tendon loads generated in response to fatigue. Seven asymptomatic players with a PTA performed five successful vertical stop-jump trials before and after a fatigue protocol. Fatigue protocol involved participants repeatedly performing sets of 30 submaximal jump exercises on a sledge apparatus followed by 30 s rest until the task failure criteria were reached...
April 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27139134/evaluation-of-a-sickle-cell-disease-educational-website-for-emergency-providers
#17
Mariam Kayle, Jill Brennan-Cook, Brigit M Carter, Anne L Derouin, Susan G Silva, Paula Tanabe
Sickle cell disease (SCD) is a complex multisystem debilitating disease. Despite its complexity, health care providers who are not SCD experts receive little formal education on SCD. An open-access, educational website, "Emergency Department Sickle Cell Disease: Crisis Management and Beyond," was created to provide education about SCD to emergency department (ED) providers who are not SCD experts but who provide care for patients with SCD. Electronic surveys were used to conduct a formal evaluation of the accuracy and relevance of the website's content, as well as the effectiveness of the education modules in improving knowledge among health care providers...
April 2016: Advanced Emergency Nursing Journal
https://www.readbyqxmd.com/read/26996237/minocycline-as-a-re-purposed-anti-wolbachia-macrofilaricide-superiority-compared-with-doxycycline-regimens-in-a-murine-infection-model-of-human-lymphatic-filariasis
#18
Raman Sharma, Ghaith Al Jayoussi, Hayley E Tyrer, Joanne Gamble, Laura Hayward, Ana F Guimaraes, Jill Davies, David Waterhouse, Darren A N Cook, Laura J Myhill, Rachel H Clare, Andrew Cassidy, Andrew Steven, Kelly L Johnston, Louise Ford, Joseph D Turner, Stephen A Ward, Mark J Taylor
Lymphatic filariasis and onchocerciasis are parasitic helminth diseases, which cause severe morbidities such as elephantiasis, skin disease and blindness, presenting a major public health burden in endemic communities. The anti-Wolbachia consortium (A·WOL: http://www.a-wol.com/) has identified a number of registered antibiotics that target the endosymbiotic bacterium, Wolbachia, delivering macrofilaricidal activity. Here we use pharmacokinetics/pharmacodynamics (PK/PD) analysis to rationally develop an anti-Wolbachia chemotherapy by linking drug exposure to pharmacological effect...
March 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/26925234/a-pilot-study-on-biomarkers-for-tendinopathy-lower-levels-of-serum-tnf-%C3%AE-and-other-cytokines-in-females-but-not-males-with-achilles-tendinopathy
#19
James E Gaida, Håkan Alfredson, Sture Forsgren, Jill L Cook
BACKGROUND: Achilles tendinopathy is a painful musculoskeletal condition that is common among athletes, and which limits training capacity and competitive performance. The lack of biomarkers for tendinopathy limits research into risk factors and also the evaluation of new treatments. Cytokines and growth factors involved in regulating the response of tendon cells to mechanical load have potential as biomarkers for tendinopathy. METHODS: This case-control study compared serum concentration of cytokines and growth factors (TNF-α, IL-1β, bFGF, PDFG-BB, IFN-γ, VEGF) between individuals with chronic Achilles tendinopathy and controls...
2016: BMC Sports Science, Medicine and Rehabilitation
https://www.readbyqxmd.com/read/26707957/do-isometric-and-isotonic-exercise-programs-reduce-pain-in-athletes-with-patellar-tendinopathy-in-season-a-randomised-clinical-trial
#20
Mathijs van Ark, Jill L Cook, Sean I Docking, Johannes Zwerver, James E Gaida, Inge van den Akker-Scheek, Ebonie Rio
OBJECTIVES: Many athletes with patellar tendinopathy participate in sports with symptoms during or after activities. Current treatments do not decrease pain in-season; eccentric exercises in-season result in an increase in pain. This study examined if isometric and isotonic exercises relieved pain in competing athletes with patellar tendinopathy. DESIGN: Randomised clinical trial. METHODS: Jumping athletes with patellar tendinopathy playing at least three times per week participated in this study...
September 2016: Journal of Science and Medicine in Sport
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