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Nicola Maffulli

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https://www.readbyqxmd.com/read/28914104/influence-of-previous-body-mass-index-and-sex-on-regional-fat-changes-in-a-weight-loss-intervention
#1
Pedro J Benito, Rocio Cupeiro, Ana B Peinado, Miguel A Rojo, Nicola Maffulli
OBJECTIVES: Men and women may lose weight in a different fashion. This study compares the changes in different anatomical regions after a well-controlled weight loss program by sex and initial BMI. METHODS: A total of 180 subjects (48 overweight women, 36 overweight men, and 48 obese women and 48 obese men) were recruited to participate in a 22-week weight loss programme (diet + exercise). RESULTS: Regarding percentage body weight change from baseline, there was no triple interaction (BMI, sex and anatomical region), but there was interaction between BMI and anatomical region (F2,840=34...
September 15, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28910993/transtendon-repair-in-partial-articular-supraspinatus-tendon-tear
#2
Leonardo Osti, Matteo Buda, Mattia Andreotti, Raffaella Osti, Leo Massari, Nicola Maffulli
Introduction: Partial thickness rotator cuff tears (PTRCTs) are common, with an incidence between 17% and 37%, and a high prevalence in throwing athletes. Different surgical procedures are suggested when partial tears involve the articular portion of the rotator cuff, including arthroscopic debridement of the tear, debridement with acromioplasty, tear completion and repair, and lately transtendon repair. This systematic review describes the transtendon repair and examines indications, contraindications, complications and clinical outcome...
September 1, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/28910987/management-of-combined-injuries-of-the-posterior-cruciate-ligament-and-posterolateral-corner-of-the-knee-a-systematic-review
#3
Stefano Petrillo, Piero Volpi, Rocco Papalia, Nicola Maffulli, Vincenzo Denaro
Background: Approximately 60% of posterior cruciate ligament (PCL) injury are associated with a posterolateral corner (PLC) tear. Sources of data: We performed a systematic review of the literature according to the PRISMA guidelines. The following key words were searched on Medline, Cochrane, EMBASE, Google Scholar, and Ovid: 'posterior cruciate ligament' or 'PCL' with 'posterolateral corner' or 'PLC' and 'chronic'; 'injury'; 'management'; 'reconstruction'; 'outcomes'; 'complications'...
September 1, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/28899898/investigating-the-association-of-rs2910164-with-cancer-in-irish-patients
#4
Terri Patricia McVeigh, Robert J Mulligan, Una Mary McVeigh, Patrick W Owens, Nicola Miller, Marcia Bell, Frederic Sebag, Carole Guerin, Denis Quill, Joanne Barnes Weidhaas, Michael Kerin, Aoife J Lowery
INTRODUCTION: Micro(mi)-RNAs are small non-coding RNA molecules that exert post-transcriptional effects on gene expression by binding with cis-regulatory regions in target messenger-(m)RNA. MiR146a has a role in inflammation, and may have a role as a tumour suppressor. The polymorphism rs2910164 in pre-mir146a has been implicated in inflammatory pathologies, including cancers of the breast and thyroid; although evidence for association is conflicting in different populations. We aimed to investigate the association of this variant with these two cancers in an Irish cohort...
September 12, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28879556/we-are-operating-too-much
#5
EDITORIAL
Nicola Maffulli
With the increase of superspecialisation, there has been a recent trend for a rising number of operations for both trauma and orthopaedic ailments. This flies against the results of properly planned, well performed, adequately powered, with clinically relevant outcome measures and long enough follow-up level I studies which challenge the received wisdom that surgery is actually superior to conservative management or even supervised neglect. This editorial outlines some of these issues, and suggests that orthopaedic and trauma surgeons should actually think twice before operating on anything that comes our way...
September 6, 2017: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/28842103/treatment-of-plantar-fasciitis-with-radial-soundwave-early-is-better-than-after-6%C3%A2-months-a-pilot-study
#6
Amol Saxena, Brian K Hong, Andrew S Yun, Nicola Maffulli, Ludger Gerdesmeyer
Extracorporeal shock wave therapy/radial soundwave therapy has been predominantly used for chronic or recalcitrant plantar fasciitis with strong scientific evidence of reliable outcomes. Most of the studies included patients with plantar fasciitis with symptoms >6 months in duration. Only 2 known studies have investigated acute plantar fasciitis, which is <6 weeks in duration. They both found suboptimal results for the use of extracorporeal shock wave therapy. To the best of our knowledge, no studies have investigated radial soundwave therapy for the subacute stage or early stage of plantar fasciitis...
September 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28842099/surgery-for-tendinopathy-of-the-main-body-of-the-achilles-tendon-no-need-to-look-for-new-solutions-when-the-old-ones-work-if-performed-well
#7
EDITORIAL
Nicola Maffulli
No abstract text is available yet for this article.
September 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28810893/subcutaneous-emphysema-of-the-leg-after-hardware-removal-and-bone-allografting-for-infected-non-union-of-the-distal-femur
#8
Vincenzo Denaro, Umile Giuseppe Longo, Giuseppe Salvatore, Vincenzo Candela, Nicola Maffulli
BACKGROUND: Infected non-unions of the supracondylar region of the femur are uncommon. Even though hardware removal is a common procedure, it may lead to complications, including neurovascular injury, refracture, worsening pain or recurrence of deformity. CASE PRESENTATION: We report on a male who developed subcutaneous emphysema of the leg after hardware removal and bone allografting for an infected non-union of the distal femur. He was managed by debridement of the surgical wound, antibiotic therapy, multiple fasciotomies, and application of a VAC (vacuum-assisted closure) system...
August 15, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28810258/prevalence-of-hyponatremia-in-patients-with-elderly-hip-fracture-a-two-year-study
#9
Rocco Aicale, Domiziano Tarantino, Nicola Maffulli
OBJECTIVE: This study investigated the prevalence of hyponatremia in elderly patients (≥ 65 years) with hip fractures. SUBJECTS AND METHODS: All records containing clinical and laboratory information of the 334 elderly patients admitted with hip fractures to the San Giovanni di Dio e Ruggi d'Aragona Hospital of Salerno (Italy) during 2014 and 2015 were retrieved from the hospital database. Patients were divided into 4 different groups, according to sex and type of hip fracture...
August 14, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/28733951/corr-insights-%C3%A2-is-dual-semitendinosus-allograft-stronger-than-turndown-for-achilles-tendon-reconstruction-an-in-vitro-analysis
#10
Nicola Maffulli
No abstract text is available yet for this article.
July 21, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28717624/ipsilateral-hamstring-tendon-graft-reconstruction-for-chronic-patellar-tendon-ruptures-surgical-technique
#11
Nicola Maffulli, Angelo Del Buono, Francesco Oliva
BACKGROUND: Patellar tendon chronic ruptures are more debated to manage that acute injuries as the patella tends to retract proximally (after 2 weeks), and surrounding soft tissues may make the repair more complicate. PURPOSE: We propose a novel technique in which the patellar tendon is reconstructed using ipsilateral hamstring tendons. This surgical procedure implies to drill a single tunnel through the patella and another through the tibia to reduce the risk of bony breakage...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28717615/outcomes-of-prolotherapy-for-intra-tendinous-achilles-tears-a-case-series
#12
Otto Chan, Ben Havard, Sarah Morton, Mel Pritchard, Nicola Maffulli, Tom Crisp, Nat Padhiar, Jeremy David Perry, John King, Dylan Morrissey
BACKGROUND: The intra-tendinous tear is a new pathology that is defined as a discontinuity of fibres situated entirely within the tendon. Prolotherapy involves injecting an irritant, such as hyperosmolar dextrose, to stimulate a tissue healing response and ultimately reduce pain. METHODS: 43 consecutive patients diagnosed with an intra-tendinous tear were included (27 males: 16 females, mean (SD) age 41 (11.3). Patients were injected with 0.4ml-1.5ml (mean 0.8ml) of 50% dextrose and 0...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28717612/intratendinous-tears-of-the-achilles-tendon-a-new-pathology-analysis-of-a-large-4-year-cohort
#13
Otto Chan, Sarah Morton, Mel Pritchard, Tina Parkes, Peter Malliaras, Tom Crisp, Nat Padhiar, Nicola Maffulli, John King, Dylan Morrissey
BACKGROUND: Achillodynia is common and includes Achilles tendinopathy, partial Achilles tears and Achilles tendon ruptures. However, we believe an additional pathology should be considered for Achillodynia differentials - the intratendinous tear (ITT). METHODS: Examinations of 740 achillodynic patients in one specialist centre were reviewed. ITTs were defined as a clearly visualised echopoor area situated centrally and extending to, but not through the tendon periphery, with pain on palpation and no clinical findings consistent with Achilles rupture...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28717611/conservative-minimally-invasive-and-open-surgical-repair-for-management-of-acute-ruptures-of-the-achilles-tendon-a-clinical-and-functional-retrospective-study
#14
Gayle Maffulli, Angelo Del Buono, Paula Richards, Francesco Oliva, Nicola Maffulli
BACKGROUND: At present, it is unclear which is the best management for Achilles tendon rupture. PURPOSE: We assess the clinical, functional and imaging outcomes of active patients undergoing 3 different types of management for acute subcutaneous rupture of the Achilles tendon, including conservative cast immobilization, traditional open surgery and percutaneous repair. METHODS: 26 active patients were managed for a rupture of the Achilles Tendon from January 2007 to March 2008...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28717606/combined-supplementation-of-ascorbic-acid-and-thyroid-hormone-t3-affects-tenocyte-proliferation-the-effect-of-ascorbic-acid-in-the-production-of-nitric-oxide
#15
Viviana di Giacomo, Martina Berardocco, Marialucia Gallorini, Francesco Oliva, Alessia Colosimo, Amelia Cataldi, Nicola Maffulli, Anna C Berardi
BACKGROUND: Tissue engineering is now increasingly focusing on cell-based treatments as promising tools to improve tendon repair. However, many crucial aspects of tendon biology remain to be understood before adopting the best experimental approach for cell-tissue engineering. METHODS: The role played by Ascorbic Acid (AA) alone and in combination with thyroid hormone T3 in the viability and proliferation of primary human tendon-derived cells was investigated. Human tenocyte viability was detected by Trypan blue exclusion test and cellular proliferation rate was evaluated by CFSE CellTrace™...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28717605/i-s-mu-l-t-first-time-patellar-dislocation-guidelines
#16
Mario Vetrano, Francesco Oliva, Salvatore Bisicchia, Michela Bossa, Angelo De Carli, Luigi Di Lorenzo, Davide Erroi, Alfonso Forte, Calogero Foti, Antonio Frizziero, Giuseppe Gasparre, Alessio Giai Via, Bernardo Innocenti, Umile Giuseppe Longo, Asmaa Mahmoud, Stefano Masiero, Daniele Mazza, Simone Natali, Christian Notarangelo, Leonardo Osti, Johnny Padulo, Leonardo Pellicciari, Fabrizio Perroni, Eleonora Piccirilli, Carlo Ramponi, Giuseppe Salvatore, Alfredo Schiavone Panni, Tania Suarez, Umberto Tarantino, Filippo Vittadini, Maria Chiara Vulpiani, Andrea Ferretti, Nicola Maffulli
Primary traumatic patellar dislocation is common, particularly in young active individuals. A consensus on its management is still lacking. The present work provides easily accessible guidelines to be considered as recommendations for a good clinical practice developed through a process of systematic review of the literature and expert opinion, to improve the quality of care and rationalize the use of resources. LEVEL OF EVIDENCE: Ia.
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28714976/rare-coding-variants-in-plcg2-abi3-and-trem2-implicate-microglial-mediated-innate-immunity-in-alzheimer-s-disease
#17
Rebecca Sims, Sven J van der Lee, Adam C Naj, Céline Bellenguez, Nandini Badarinarayan, Johanna Jakobsdottir, Brian W Kunkle, Anne Boland, Rachel Raybould, Joshua C Bis, Eden R Martin, Benjamin Grenier-Boley, Stefanie Heilmann-Heimbach, Vincent Chouraki, Amanda B Kuzma, Kristel Sleegers, Maria Vronskaya, Agustin Ruiz, Robert R Graham, Robert Olaso, Per Hoffmann, Megan L Grove, Badri N Vardarajan, Mikko Hiltunen, Markus M Nöthen, Charles C White, Kara L Hamilton-Nelson, Jacques Epelbaum, Wolfgang Maier, Seung-Hoan Choi, Gary W Beecham, Cécile Dulary, Stefan Herms, Albert V Smith, Cory C Funk, Céline Derbois, Andreas J Forstner, Shahzad Ahmad, Hongdong Li, Delphine Bacq, Denise Harold, Claudia L Satizabal, Otto Valladares, Alessio Squassina, Rhodri Thomas, Jennifer A Brody, Liming Qu, Pascual Sánchez-Juan, Taniesha Morgan, Frank J Wolters, Yi Zhao, Florentino Sanchez Garcia, Nicola Denning, Myriam Fornage, John Malamon, Maria Candida Deniz Naranjo, Elisa Majounie, Thomas H Mosley, Beth Dombroski, David Wallon, Michelle K Lupton, Josée Dupuis, Patrice Whitehead, Laura Fratiglioni, Christopher Medway, Xueqiu Jian, Shubhabrata Mukherjee, Lina Keller, Kristelle Brown, Honghuang Lin, Laura B Cantwell, Francesco Panza, Bernadette McGuinness, Sonia Moreno-Grau, Jeremy D Burgess, Vincenzo Solfrizzi, Petra Proitsi, Hieab H Adams, Mariet Allen, Davide Seripa, Pau Pastor, L Adrienne Cupples, Nathan D Price, Didier Hannequin, Ana Frank-García, Daniel Levy, Paramita Chakrabarty, Paolo Caffarra, Ina Giegling, Alexa S Beiser, Vilmantas Giedraitis, Harald Hampel, Melissa E Garcia, Xue Wang, Lars Lannfelt, Patrizia Mecocci, Gudny Eiriksdottir, Paul K Crane, Florence Pasquier, Virginia Boccardi, Isabel Henández, Robert C Barber, Martin Scherer, Lluis Tarraga, Perrie M Adams, Markus Leber, Yuning Chen, Marilyn S Albert, Steffi Riedel-Heller, Valur Emilsson, Duane Beekly, Anne Braae, Reinhold Schmidt, Deborah Blacker, Carlo Masullo, Helena Schmidt, Rachelle S Doody, Gianfranco Spalletta, W T Longstreth Jr, Thomas J Fairchild, Paola Bossù, Oscar L Lopez, Matthew P Frosch, Eleonora Sacchinelli, Bernardino Ghetti, Qiong Yang, Ryan M Huebinger, Frank Jessen, Shuo Li, M Ilyas Kamboh, John Morris, Oscar Sotolongo-Grau, Mindy J Katz, Chris Corcoran, Melanie Dunstan, Amy Braddel, Charlene Thomas, Alun Meggy, Rachel Marshall, Amy Gerrish, Jade Chapman, Miquel Aguilar, Sarah Taylor, Matt Hill, Mònica Díez Fairén, Angela Hodges, Bruno Vellas, Hilkka Soininen, Iwona Kloszewska, Makrina Daniilidou, James Uphill, Yogen Patel, Joseph T Hughes, Jenny Lord, James Turton, Annette M Hartmann, Roberta Cecchetti, Chiara Fenoglio, Maria Serpente, Marina Arcaro, Carlo Caltagirone, Maria Donata Orfei, Antonio Ciaramella, Sabrina Pichler, Manuel Mayhaus, Wei Gu, Alberto Lleó, Juan Fortea, Rafael Blesa, Imelda S Barber, Keeley Brookes, Chiara Cupidi, Raffaele Giovanni Maletta, David Carrell, Sandro Sorbi, Susanne Moebus, Maria Urbano, Alberto Pilotto, Johannes Kornhuber, Paolo Bosco, Stephen Todd, David Craig, Janet Johnston, Michael Gill, Brian Lawlor, Aoibhinn Lynch, Nick C Fox, John Hardy, Roger L Albin, Liana G Apostolova, Steven E Arnold, Sanjay Asthana, Craig S Atwood, Clinton T Baldwin, Lisa L Barnes, Sandra Barral, Thomas G Beach, James T Becker, Eileen H Bigio, Thomas D Bird, Bradley F Boeve, James D Bowen, Adam Boxer, James R Burke, Jeffrey M Burns, Joseph D Buxbaum, Nigel J Cairns, Chuanhai Cao, Chris S Carlson, Cynthia M Carlsson, Regina M Carney, Minerva M Carrasquillo, Steven L Carroll, Carolina Ceballos Diaz, Helena C Chui, David G Clark, David H Cribbs, Elizabeth A Crocco, Charles DeCarli, Malcolm Dick, Ranjan Duara, Denis A Evans, Kelley M Faber, Kenneth B Fallon, David W Fardo, Martin R Farlow, Steven Ferris, Tatiana M Foroud, Douglas R Galasko, Marla Gearing, Daniel H Geschwind, John R Gilbert, Neill R Graff-Radford, Robert C Green, John H Growdon, Ronald L Hamilton, Lindy E Harrell, Lawrence S Honig, Matthew J Huentelman, Christine M Hulette, Bradley T Hyman, Gail P Jarvik, Erin Abner, Lee-Way Jin, Gyungah Jun, Anna Karydas, Jeffrey A Kaye, Ronald Kim, Neil W Kowall, Joel H Kramer, Frank M LaFerla, James J Lah, James B Leverenz, Allan I Levey, Ge Li, Andrew P Lieberman, Kathryn L Lunetta, Constantine G Lyketsos, Daniel C Marson, Frank Martiniuk, Deborah C Mash, Eliezer Masliah, Wayne C McCormick, Susan M McCurry, Andrew N McDavid, Ann C McKee, Marsel Mesulam, Bruce L Miller, Carol A Miller, Joshua W Miller, John C Morris, Jill R Murrell, Amanda J Myers, Sid O'Bryant, John M Olichney, Vernon S Pankratz, Joseph E Parisi, Henry L Paulson, William Perry, Elaine Peskind, Aimee Pierce, Wayne W Poon, Huntington Potter, Joseph F Quinn, Ashok Raj, Murray Raskind, Barry Reisberg, Christiane Reitz, John M Ringman, Erik D Roberson, Ekaterina Rogaeva, Howard J Rosen, Roger N Rosenberg, Mark A Sager, Andrew J Saykin, Julie A Schneider, Lon S Schneider, William W Seeley, Amanda G Smith, Joshua A Sonnen, Salvatore Spina, Robert A Stern, Russell H Swerdlow, Rudolph E Tanzi, Tricia A Thornton-Wells, John Q Trojanowski, Juan C Troncoso, Vivianna M Van Deerlin, Linda J Van Eldik, Harry V Vinters, Jean Paul Vonsattel, Sandra Weintraub, Kathleen A Welsh-Bohmer, Kirk C Wilhelmsen, Jennifer Williamson, Thomas S Wingo, Randall L Woltjer, Clinton B Wright, Chang-En Yu, Lei Yu, Fabienne Garzia, Feroze Golamaully, Gislain Septier, Sebastien Engelborghs, Rik Vandenberghe, Peter P De Deyn, Carmen Muñoz Fernadez, Yoland Aladro Benito, Hakan Thonberg, Charlotte Forsell, Lena Lilius, Anne Kinhult-Stählbom, Lena Kilander, RoseMarie Brundin, Letizia Concari, Seppo Helisalmi, Anne Maria Koivisto, Annakaisa Haapasalo, Vincent Dermecourt, Nathalie Fievet, Olivier Hanon, Carole Dufouil, Alexis Brice, Karen Ritchie, Bruno Dubois, Jayanadra J Himali, C Dirk Keene, JoAnn Tschanz, Annette L Fitzpatrick, Walter A Kukull, Maria Norton, Thor Aspelund, Eric B Larson, Ron Munger, Jerome I Rotter, Richard B Lipton, María J Bullido, Albert Hofman, Thomas J Montine, Eliecer Coto, Eric Boerwinkle, Ronald C Petersen, Victoria Alvarez, Fernando Rivadeneira, Eric M Reiman, Maura Gallo, Christopher J O'Donnell, Joan S Reisch, Amalia Cecilia Bruni, Donald R Royall, Martin Dichgans, Mary Sano, Daniela Galimberti, Peter St George-Hyslop, Elio Scarpini, Debby W Tsuang, Michelangelo Mancuso, Ubaldo Bonuccelli, Ashley R Winslow, Antonio Daniele, Chuang-Kuo Wu, Oliver Peters, Benedetta Nacmias, Matthias Riemenschneider, Reinhard Heun, Carol Brayne, David C Rubinsztein, Jose Bras, Rita Guerreiro, Ammar Al-Chalabi, Christopher E Shaw, John Collinge, David Mann, Magda Tsolaki, Jordi Clarimón, Rebecca Sussams, Simon Lovestone, Michael C O'Donovan, Michael J Owen, Timothy W Behrens, Simon Mead, Alison M Goate, Andre G Uitterlinden, Clive Holmes, Carlos Cruchaga, Martin Ingelsson, David A Bennett, John Powell, Todd E Golde, Caroline Graff, Philip L De Jager, Kevin Morgan, Nilufer Ertekin-Taner, Onofre Combarros, Bruce M Psaty, Peter Passmore, Steven G Younkin, Claudine Berr, Vilmundur Gudnason, Dan Rujescu, Dennis W Dickson, Jean-François Dartigues, Anita L DeStefano, Sara Ortega-Cubero, Hakon Hakonarson, Dominique Campion, Merce Boada, John Keoni Kauwe, Lindsay A Farrer, Christine Van Broeckhoven, M Arfan Ikram, Lesley Jones, Jonathan L Haines, Christophe Tzourio, Lenore J Launer, Valentina Escott-Price, Richard Mayeux, Jean-François Deleuze, Najaf Amin, Peter A Holmans, Margaret A Pericak-Vance, Philippe Amouyel, Cornelia M van Duijn, Alfredo Ramirez, Li-San Wang, Jean-Charles Lambert, Sudha Seshadri, Julie Williams, Gerard D Schellenberg
We identified rare coding variants associated with Alzheimer's disease in a three-stage case-control study of 85,133 subjects. In stage 1, we genotyped 34,174 samples using a whole-exome microarray. In stage 2, we tested associated variants (P < 1 × 10(-4)) in 35,962 independent samples using de novo genotyping and imputed genotypes. In stage 3, we used an additional 14,997 samples to test the most significant stage 2 associations (P < 5 × 10(-8)) using imputed genotypes. We observed three new genome-wide significant nonsynonymous variants associated with Alzheimer's disease: a protective variant in PLCG2 (rs72824905: p...
September 2017: Nature Genetics
https://www.readbyqxmd.com/read/28714236/effectiveness-of-tissue-engineered-three-dimensional-bioactive-graft-on-bone-healing-and-regeneration-an-in-vivo-study-with-significant-clinical-value
#18
Mostafa Shahrezaie, Ali Moshiri, Babak Shekarchi, Ahmad Oryan, Nicola Maffulli, Javad Parvizi
Several strategies have been used to promote bone repair; with many failing due to the lack of osteoinduction. We describe our approach for promoting bone healing that attempts to overcome prior shortcomings. First, we compared the role of different concentrations of Gelatin (Gel), nanostructured-hydroxyapatite (nHA), Simvastatin (Sim) and nHA-Sim particles on healing of small femoral bone defects in rabbits. The effective concentration of each of them was studied, and then a three-dimensional porous scaffold was designed using Gel, nHA and Sim which was then cross-linked with Genipin...
July 17, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28659242/minimally-invasive-achilles-tendon-stripping-for-the-management-of-tendinopathy-of-the-main-body-of-the-achilles-tendon
#19
Nicola Maffulli, Francesco Oliva, Gayle D Maffulli, Alessio Giai Via, Nikolaos Gougoulias
Achilles tendinopathy is a common cause of disability. New nerves fibers grow from the paratenon into the Achilles tendon, and they could play a central role in the development of pain. We report the results of minimally invasive Achilles tendon stripping for Achilles tendinopathy in 47 active patients. The Victorian Institute of Sports Assessment-Achilles questionnaire score improved from 53.8 preoperatively to 85.3 postoperatively (p < .001). After a mean follow-up period of 40.5 months, 41 patients had resumed sporting activities at an average of 3...
June 25, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28602482/a-new-anterior-inferior-coronal-patellar-plica
#20
Francesco Sadile, Alessio Bernasconi, Nicola Maffulli
PURPOSE: To date, four synovial plicae are classically described in the knee. We report a previously undescribed new inferior patellar plica, named "bib-like plica" (BLP, referring to its morphology) related to specific symptoms of atypical recurrent anterior knee pain in the presence of a locked or pseudo-locked knee. We describe this anatomical structure, and assess its clinical relevance in daily practice in terms of clinical pattern and long-term follow-up outcome after arthroscopic excision...
June 8, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
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