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Nicola Maffulli

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https://www.readbyqxmd.com/read/29729756/editorial-commentary-hip-trochanteric-bursitis-and-femoroacetabular-impingement-the-arthroscope-is-only-the-tool
#1
EDITORIAL
Nicola Maffulli
Lateral hip pain is debilitating, with pain located at or around the greater trochanter, and trochanteric bursitis is one of the conditions that are part of the greater trochanter pain syndrome. At times, trochanteric bursitis coexists with femoroacetabular impingement. In such cases, the arthroscope is used as a soft tissue endoscope facilitating debridement of the bursa and functional lengthening of the fascia lata. Coupled with appropriate femoroacetabular impingement treatment and rehabilitation, the procedure allows predictable functional results...
May 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29722769/alternatives-to-biologics-in-management-of-knee-osteoarthritis-a-systematic-review
#2
Fadi Hassan, William D Murrell, Andrew Refalo, Nicola Maffulli
BACKGROUND: Knee osteoarthritis (KOA) is a common condition encountered by physicians. KOA is addressed by a wide array of modalities including a number of nonbiological treatments. METHODS: PubMed, ISI Web of Science, and SPORTDiscus were searched for level 1 to 4 studies published from inception to August 2017. RESULTS: A total of 18 studies were evaluated and results demonstrated moderate supporting evidence for prolotherapy and limited evidence for botulinum toxin type A, sodium bicarbonate and calcium gluconate, and low-molecular weight fraction of 5% human serum albumin...
June 2018: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/29722767/amniotic-epithelial-stem-cells-salient-features-and-possible-therapeutic-role
#3
Aurelio Muttini, Barbara Barboni, Luca Valbonetti, Valentina Russo, Nicola Maffulli
This is a study of amniotic epithelial cells, which form the innermost layer of the amniotic membrane. These cells can be easily isolated and display peculiar and unique properties, such as plasticity and differentiation potential toward the 3 germinal layers, that may aid regeneration and/or repair of damaged or diseased tissues and organs. A robust literature based on in vitro, experimental, and clinical studies in large animals demonstrates that these cells can enhance the regeneration of tendons, bone, and articular cartilage...
June 2018: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/29722766/microcapsule-technology-for-controlled-growth-factor-release-in-musculoskeletal-tissue-engineering
#4
Giovanna Della Porta, Maria C Ciardulli, Nicola Maffulli
Tissue engineering strategies have relied on engineered 3-dimensional (3D) scaffolds to provide architectural templates that can mimic the native cell environment. Among the several technologies proposed for the fabrication of 3D scaffold, that can be attractive for stem cell cultivation and differentiation, moulding or bioplotting of hydrogels allow the stratification of layers loaded with cells and with specific additives to obtain a predefined microstructural organization. Particularly with bioplotting technology, living cells, named bio-ink, and additives, such as biopolymer microdevices/nanodevices for the controlled delivery of growth factors or biosignals, can be organized spatially into a predesigned 3D pattern by automated fabrication with computer-aided digital files...
June 2018: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/29722765/making-them-commit-strategies-to-influence-phenotypic-differentiation-in-mesenchymal-stem-cells
#5
Alessio Giai Via, Mary B McCarthy, Laura de Girolamo, Enrico Ragni, Francesco Oliva, Nicola Maffulli
Tendon injuries, bone defects, and cartilage defects are complex clinical conditions leading to pain and dysfunctions. Tendon, bone, and cartilage are highly specialized and organized tissues, and the self-healing may be limited by their histologic features, or impaired by the local conditions. Furthermore, the resultant tissue often shows inferior properties compared with native tissue, leading to high rates of reruptures and revision surgeries. A growing field of research has explored tendon, bone, and cartilage regeneration using mesenchymal stem cells (MSCs), because of their multipotency, and because they are relatively easy to harvest...
June 2018: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/29722764/platelet-rich-plasma-and-mesenchymal-stem-cells-exciting-but-%C3%A2-are-we-there-yet
#6
Isabel Andia, Jose I Martin, Nicola Maffulli
Joint conditions incapacitate free movement driving to a sedentary lifestyle, a major risk factor for chronic diseases. Regenerative procedures, involving the use of mesenchymal stem/stromal cells along with platelet-rich plasma (PRP), can help patients with these conditions. We describe the main characteristics of cellular products (bone marrow concentrate, stromal vascular fraction of adipose tissue, and mesenchymal stem/stromal cells derived from these tissues), and the potential benefits of combination with PRP in 3 scenarios: PRP lysates used during laboratory cell expansion; PRP to prime cellular products or the host tissue before cell implantation; PRP used as a vehicle for cell transplantation and to provide trophic signals...
June 2018: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/29722763/cell-therapies-in-tendon-ligament-and-musculoskeletal-system-repair
#7
Pilar M de Albornoz, Rocco Aicale, Francisco Forriol, Nicola Maffulli
In the last few decades, several techniques have been used to optimize tendon, ligament, and musculoskeletal healing. The evidence in favor of these techniques is still not proven, and level I studies are lacking. We performed an analysis of the therapeutic strategies and tissue engineering projects recently published in this field. Here, we try to give an insight into the current status of cell therapies and the latest techniques of bioengineering applied to the field of orthopedic surgery. The future areas for research in the management of musculoskeletal injuries are outlined...
June 2018: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/29722761/biological-therapies-in-orthopedic-sports-medicine
#8
Nicola Maffulli, F Alan Barber
No abstract text is available yet for this article.
June 2018: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/29720223/greater-rate-of-cephalic-screw-mobilisation-following-proximal-femoral-nailing-in-hip-fractures-with-a-tip-apex-distance-tad-and-a-calcar-referenced-tad-greater-than-25-mm
#9
Rocco Aicale, Nicola Maffulli
BACKGROUND: To ascertain whether the tip-apex distance (TAD), calcar referenced TAD (CalTAD), and the sum of both (TADcalTAD) are predictive measurements of mobilisation of the cephalic screw in patients with trochanteric hip fractures. METHODS: Between 2014 and 2015, 68 patients (mean age 86 years, 45 females, 23 males) with a trochanteric hip fracture underwent intramedullary nailing. The TAD and CalTAD were measured, and for each parameter, we calculated sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV)...
May 2, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29659726/dubious-space-for-artelon-joint-resurfacing-for-basal-thumb-trapeziometacarpal-joint-osteoarthritis-a-systematic-review
#10
Francesco Smeraglia, Massimo Mariconda, Giovanni Balato, Sigismondo Luca Di Donato, Giovanni Criscuolo, Nicola Maffulli
Introduction: Trapeziometacarpal arthritis is a common and disabling condition. There is no evidence in the literature of superiority of one surgical procedure over others. Several prosthetic implants have been introduced to preserve joint mobility. Sourced of data: We searched the on Medline (PubMed), Web of Science and Scopus databases using the combined keywords 'artelon', 'thumb', 'carpometacarpal', 'trapeziometacarpal' and 'rhizoarthrosis'; 11 studies were identified...
April 6, 2018: British Medical Bulletin
https://www.readbyqxmd.com/read/29642914/development-of-the-italian-version-of-the-high-activity-arthroplasty-score-haas-i-following-hip-and-knee-total-arthroplasty-cross-cultural-adaptation-reliability-validity-and-sensitivity-to-change
#11
Marco Monticone, Antonio Capone, Luca Frigau, Giuseppe Marongiu, Paola Abelli, Francesco Mola, Nicola Maffulli, Calogero Foti
BACKGROUND: The number of physically active individuals who develop knee and hip arthritis and who undergo arthroplasties of these joints ie ever increasing. It has become necessary to develop evaluation scales which address the specific issues raised by such individuals. The High Activity Arthroplasty Score is one such scales, originally developed in English. METHODS: The HAAS-I was developed by means of forward-backward translation, a final review by an expert committee and a test of the pre-final version to establish its correspondence with the original English version...
April 11, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29622243/editorial-commentary-standing-the-test-of-time-and-sport-fulkerson-tibial-tubercle-osteotomy-of-the-knee
#12
EDITORIAL
Nicola Maffulli
A biplanar osteotomy aiming to anteromedialize the anterior tibial tuberosity to realign the patellofemoral joint described by Prof. Fulkerson is one of the classical operations to address many pathologies of the patellofemoral joint. The procedure is evidence-based and effective for the management of patellofemoral pain and osteoarthritis, confirming that the original ideas and concepts are still valid, and still stand strong. In high-demand patients, the Fulkerson osteotomy offers good opportunities of success in terms of return to sport...
April 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29532899/matrix-metalloproteinase-1-mmp-1-and-mmp-8-gene-polymorphisms-promote-increase-and-remodeling-of-the-collagen-iii-and-v-in-posterior-tibial-tendinopathy
#13
Tulio Diniz-Fernandes, Alexandre Leme Godoy-Santos, Maria Cristina Santos, Pedro Pontin, Caio Augusto Alves Pereira, Yuri Justi Jardim, Ana Paula Pereira Velosa, Nicola Maffulli, Walcy Rosolia Teodoro, Vera Luiza Capelozzi
Posterior tibial tendinopathy (PTT) can lead to acquired flatfoot in adults. Many patients develop PTT without any identifiable risk factors. Molecular changes in extracellular matrix (ECM) and matrix metalloproteinase (MMP) polymorphism may influence the risk of developing PTT. We aim to investigate the association between matrix metalloproteinase-1 (MMP-1) and (MMP-8) gene polymorphisms with changes in collagen I, III and V in PTT. A case-control study with 22 patients and 5 controls was performed. The MMP-1 (2G/2G) and MMP-8 (T/T) genotypes were determined by PCR-restriction fragment length polymorphism...
March 13, 2018: Histology and Histopathology
https://www.readbyqxmd.com/read/29502704/editorial-commentary-paving-a-road-requires-a-well-mixed-cement-stem-cells-platelet-rich-plasma-and-shoulder-rotator-cuff-healing
#14
EDITORIAL
Nicola Maffulli
The process of healing in musculoskeletal tissues is complex, and the addition of devices, including platelet-rich plasma and mesenchymal stem cells, to biologically enhance it may favor its optimization. This work shows in a compelling fashion that it is possible to produce the right admixture of physical and biological factors to make it happen in rotator cuff repair.
March 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29492109/higher-frequency-of-hamstring-injuries-in-elite-track-and-field-athletes-who-had-a-previous-injury-to-the-ankle-a-17-years-observational-cohort-study
#15
Nikolaos Malliaropoulos, Georgios Bikos, Maria Meke, Korakakis Vasileios, Xavier Valle, Heinz Lohrer, Nicola Maffulli, Nat Padhiar
Background: Inversion injury to the ankle and hamstring injuries are common problems in most sports. It is not known whether these injuries constitute a predisposing factor or a precursor of injury or re-injury of these anatomical locations. Therefore, we wished to test the hypothesis that a previous inversion ankle injury exerted a significant effect on the chance of an athlete suffering from a subsequent ipsilateral hamstring injury and vice versa. Methods: In an observational cohort study over 17 years (1998-2015), 367 elite track and field athletes, were grouped according to their first traumatic isolated ankle or hamstring injury...
2018: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29409243/high-resolution-real-time-ultrasonography-of-the-sural-nerve-after-percutaneous-repair-of-the-achilles-tendon
#16
Marcello Zappia, Daniela Berritto, Francesco Oliva, Nicola Maffulli
BACKGROUND: Percutaneous Achilles tendon repair has been developed to minimise soft tissue complications following treatment of tendon ruptures. However, there are concerns because of the risk of sural nerve injury. Few studies have investigated the relationship between the Achilles tendon, the sural nerve and its several anatomical course variants. METHODS: We studied 7 cadaveric limbs (7 Achilles tendons) in which a percutaneous repair of the Achilles tendon was performed...
March 30, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29409217/surgical-management-of-chronic-achilles-tendon-ruptures-using-less-invasive-techniques
#17
Nicola Maffulli, Francesco Oliva, Gayle D Maffulli, Angelo Del Buono, Nikolaos Gougoulias
BACKGROUND: Surgical management of chronic Tendo Achillis (TA) ruptures usually requires tendon grafting procedures. Several techniques have been described. We examined the outcome of three different less invasive (incisions length less than 3 cm) tendon transfer techniques in the management of patients with a chronic rupture of the TA. METHODS: Of 62 patients (39 males and 23 females; mean age 44.8 years; range 29.3-62 years) with chronic TA ruptures managed operatively, 21 patients had a ≥6cm gap and underwent free ipsilateral semitendinosus (ST) graft (21 patients), whereas patients with smaller gaps had either ipsilateral peroneus brevis (PB) (20 patients) or ipsilateral flexor hallucis longus (FHL) transfer (21 patients)...
April 2018: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29387643/correlation-between-time-from-injury-to-surgery-and-the-prevalence-of-ramp-and-hidden-lesions-during-anterior-cruciate-ligament-reconstruction-a-new-diagnostic-algorithm
#18
Gianni Di Vico, Sigismondo Luca Di Donato, Giovanni Balato, Gaetano Correra, Alessio D'Addona, Nicola Maffulli, Donato Rosa
Background: Anterior cruciate ligament tears (ACL) are associated with meniscal lesions, that could involve the posterior horn of the medial meniscus (PHMM). A variety of techniques has been proposed to better visualise the postero-medial (PM) compartment. The aim of the study is to evaluate the prevalence of longitudinal tears of peripheral attachment of the PHMM during arthroscopic ACL reconstruction, and to describe a diagnostic algorithm. Methods: 115 patients who underwent arthroscopic ACL reconstruction were enrolled for the study...
July 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/29387639/prevalence-techniques-and-knowledge-of-rapid-weight-loss-amongst-adult-british-judo-athletes-a-questionnaire-based-study
#19
Nikos Malliaropoulos, Shaan Rachid, Vasileios Korakakis, Stephen Andrew Fraser, Georgios Bikos, Nicola Maffulli, Manuela Angioi
Background: No investigation has analysed the RWL approaches since new rules by the International Judo Federation (IJF) regarding weigh-ins have been implemented in international competitions in 2014. The current study analyses the prevalence, most common methods and knowledge surrounding the effects of rapid weight loss (RWL) amongst adult UK judo athletes. Additionally, it examines differences in rapid weight loss behaviour (RWLB) between gender, weight-class, competitive level, age RWL began and "high"/"low" knowledge athletes...
July 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/29387632/i-performed-experiments-and-i-have-results-wow-and-now
#20
EDITORIAL
Johnny Padulo, Andrea De Giorgio, Francesco Oliva, Antonio Frizziero, Nicola Maffulli
Writing a scientific article is not an easy task, but it is definitely a great satisfaction to be able to conclude and publish it. Indeed, each publication is a service we make to the entire scientific community and to the advancement of science even before our personal career. There is and there will not be a final book/article for writing a scientific paper. Therefore, some knowledge is a decisive factor to increase the chances of our work being accepted by a specialized scientific journal. The purpose of this editorial is to trace an ideal path, based on our personal experience, useful to properly structure a scientific article, from bibliographic research to cover letter...
July 2017: Muscles, Ligaments and Tendons Journal
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