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https://www.readbyqxmd.com/read/27911127/immediate-and-lasting-effects-of-a-thoracic-spine-manipulation-in-a-patient-with-signs-of-cervical-radiculopathy-and-upper-extremity-hyperalgesia-a-case-report
#1
Beth K Deschenes, Jason Zafereo
Patients with cervical radiculopathy (CR) may present with accompanying symptoms of hyperalgesia, allodynia, heaviness in the arm, and non-segmental pain that do not appear to be related to a peripheral spinal nerve. These findings may suggest the presence of central or autonomic nervous system involvement, requiring a modified management approach. The purpose of this case report is to describe the treatment of a patient with signs of CR and upper extremity (UE) hyperalgesia who had a significant decrease in her UE pain and hypersensitivity after a single thoracic spine manipulation (TSM)...
December 2, 2016: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/27894349/-when-i-saw-walking-i-just-kind-of-took-it-as-wheeling-interpretations-of-mobility-related-items-in-generic-preference-based-health-state-instruments-in-the-context-of-spinal-cord-injury
#2
Yvonne Anne Michel, Lidia Engel, Kim Rand-Hendriksen, Liv Ariane Augestad, David Gt Whitehurst
BACKGROUND: In health economic analyses, health states are typically valued using instruments with few items per dimension. Due to the generic (and often reductionist) nature of such instruments, certain groups of respondents may experience challenges in describing their health state. This study is concerned with generic, preference-based health state instruments that provide information for decisions about the allocation of resources in health care. Unlike physical measurement instruments, preference-based health state instruments provide health state values that are dependent on how respondents interpret the items...
November 28, 2016: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/27893643/early-percutaneous-dilational-tracheostomy-does-not-lead-to-an-increased-risk-of-surgical-site-infection-following-anterior-spinal-surgery
#3
Chris Kaczmarek, Mirko Aach, Martin F Hoffmann, Emre Yilmaz, Christian Waydhas, Thomas A Schildhauer, Uwe Hamsen
BACKGROUND: Most patients suffering cervical spinal cord injuries require tracheostomy. The optimal timing is still a matter of debate. Previous studies showed that patients receiving early tracheostomy had fewer ventilator days, decreased rates of pneumonia, and were mobilized earlier. Due to the proximity of the anterior approach to the tracheostoma, there is concern about an increased risk of surgical site infection related to tracheostomy. METHODS: Retrospective analysis at a Level 1 trauma center of patient records from 2008-2014, identifying all patients with spinal cord injury who received anterior cervical spinal surgery and had early percutaneous dilational tracheostomy...
November 23, 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27892796/using-a-divided-attention-stepping-accuracy-task-to-improve-balance-and-functional-outcomes-in-an-individual-with-incomplete-spinal-cord-injury-a-case-report
#4
Susan J Leach, Richard A Magill, Joyce R Maring
A spinal cord injury (SCI) frequently results in impaired balance, endurance, and strength with subsequent limitations in functional mobility and community participation. The purpose of this case report was to implement a training program for an individual with a chronic incomplete SCI using a novel divided-attention stepping accuracy task (DASAT) to determine if improvements could be made in impairments, activities, and participation. The client was a 51-year-old male with a motor incomplete C4 SCI sustained 4 years prior...
November 28, 2016: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/27887637/clinical-improvement-and-reduction-in-serum-calprotectin-levels-after-an-intensive-exercise-programme-for-patients-with-ankylosing-spondylitis-and-non-radiographic-axial-spondyloarthritis
#5
Andrea Levitova, Hana Hulejova, Maja Spiritovic, Karel Pavelka, Ladislav Senolt, Marketa Husakova
BACKGROUND: The efficacy of exercise therapy for ankylosing spondylitis (AS) is well-documented, but dearth of information is for non-radiographic axial spondyloarthritis (nr-axSpA). Biomarkers like serum calprotectin, interleukins IL-6, IL-17 and tumour necrosis factor (TNF)-α may reflect the disease activity of axial spondyloarthritis (axSpA). In this study, we investigated clinical and laboratory parameters of both axSpA subgroups in response to intensive physical exercise. METHODS: Altogether, 46 patients with axSpA, characterised according to the Assessment of SpondyloArthritis International Society criteria as having nr-axSpA or AS underwent 6-month exercise programme...
November 25, 2016: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/27886877/minimally-invasive-treatment-of-spine-trauma
#6
REVIEW
Jason E McGowan, Christian B Ricks, Adam S Kanter
The role for minimally invasive surgery (MIS) continues to expand in the management of spinal pathology. In the setting of trauma, operative techniques that can minimize morbidity without compromising clinical efficacy have significant value. MIS techniques are associated with decreased intraoperative blood loss, operative time, and morbidity, while providing patients with comparable outcomes when compared with conventional open procedures. MIS interventions further enable earlier mobilization, decreased hospital stay, decreased pain, and an earlier return to baseline function when compared with traditional techniques...
January 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/27871910/pharmacological-studies-on-the-nop-and-opioid-receptor-agonist-pwt2-dmt-1-n-ofq-1-13
#7
Maria Camilla Cerlesi, Huiping Ding, Mark F Bird, Norikazu Kiguchi, Federica Ferrari, Davide Malfacini, Anna Rizzi, Chiara Ruzza, David G Lambert, Mei-Chuan Ko, Girolamo Calo, Remo Guerrini
An innovative chemical strategy named peptide welding technology (PWT) has been developed for the facile synthesis of tetrabranched peptides. [Dmt(1)]N/OFQ(1-13)-NH2 acts as a universal agonist for nociceptin/orphanin FQ (N/OFQ) and classical opioid receptors. The present study investigated the pharmacological profile of the PWT derivative of [Dmt(1)]N/OFQ(1-13)NH2 (PWT2-[Dmt(1)]) in several assays in vitro and in vivo after spinal administration in monkeys subjected to the tail withdrawal assay. PWT2-[Dmt(1)] mimicked the effects of [Dmt(1)]N/OFQ(1-13)-NH2 displaying full agonist activity, similar affinity/potency and selectivity at human recombinant N/OFQ (NOP) and opioid receptors in receptor binding, stimulation of [(35)S]GTPγS binding, calcium mobilization in cells expressing chimeric G proteins, and BRET studies for measuring receptor/G-protein and receptor/β-arrestin 2 interaction...
November 19, 2016: European Journal of Pharmacology
https://www.readbyqxmd.com/read/27869581/physical-activity-in-ankylosing-spondylitis-evaluation-and-analysis-of-an-ehealth-tool
#8
Jess Shelagh Tyrrell, Clare Helen Redshaw
BACKGROUND: Ankylosing spondylitis (AS) is a chronic inflammatory condition characterised by spinal arthritis and exercise is often recommended to reduce the symptoms and improve mobility. However, very little evidence exists for the value of exercise in AS. OBJECTIVES: Firstly, this pilot study aimed to evaluate an eHealth tool, the AS Observer, specifically designed to monitor symptoms, quality of life and physical activity in AS, in terms of patient experience and suitability in generating data for epidemiological studies...
July 4, 2016: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/27858894/preoperative-deep-vein-thrombosis-in-patients-with-cervical-spondylotic-myelopathy-scheduled-for-spinal-surgery
#9
Le Liu, Yan-Bin Liu, Jian-Min Sun, Hai-Feng Hou, Chen Liang, Tao Li, Heng-Tao Qi
INTRODUCTION: The prevalence of deep vein thrombosis (DVT) and its risk factors in patients with cervical spondylotic myelopathy (CSM) before spinal surgery are poorly understood. We investigated this association with a retrospective cross-sectional study. PATIENTS CONCERNS: The study cohort consisted of all consecutive patients with CSM who were scheduled for spinal surgery at our institution from 2013 to 2015. DVT was defined as an intraluminal filling defect in a lower extremity vein identified by Doppler ultrasonography...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27857857/predictive-parameters-for-the-antecedent-development-of-hip-pathology-associated-with-long-segment-fusions-to-the-pelvis-for-the-treatment-of-adult-spinal-deformity
#10
Merritt D Kinon, Rani Nasser, Jonathan P Nakhla, Owoicho Adogwa, Jessica R Moreno, Michael Harowicz, Terence Verla, Reza Yassari, Carlos A Bagley
BACKGROUND: The surgical treatment of adult scoliosis frequently involves long segment fusions across the lumbosacral joints that redistribute tremendous amounts of force to the remaining mobile spinal segments as well as to the pelvis and hip joints. Whether or not these forces increase the risk of femoral bone pathology remains unknown. The aim of this study is to determine the correlation between long segment spinal fusions to the pelvis and the antecedent development of degenerative hip pathologies as well as what predictive patient characteristics, if any, correlate with their development...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27857638/changes-in-muscle-spasticity-in-patients-with-cerebral-palsy-after-spinal-manipulation-case-series
#11
Oleh Kachmar, Taras Voloshyn, Mykhailo Hordiyevych
OBJECTIVE: The purpose of this case series was to report quantitative changes in wrist muscle spasticity in children with cerebral palsy after 1 spinal manipulation (SM) and a 2-week course of treatment. METHODS: Twenty-nine patients, aged 7 to 18 years, with spastic forms of cerebral palsy and without fixed contracture of the wrist, were evaluated before initiation of treatment, after 1 SM, and at the end of a 2-week course of treatment. Along with daily SM, the program included physical therapy, massage, reflexotherapy, extremity joint mobilization, mechanotherapy, and rehabilitation computer games for 3 to 4 hours' duration...
December 2016: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/27856380/t9-versus-t10-as-the-upper-instrumented-vertebra-for-correction-of-adult-deformity-rationale-and-recommendations
#12
Hwee Weng Dennis Hey, Kimberly-Anne Tan, Christabel Shao-En Neo, Eugene Tze-Chun Lau, Denise Ai-Wen Choong, Leok-Lim Lau, Gabriel Ka-Po Liu, Hee-Kit Wong
BACKGROUND CONTEXT: Adult spinal deformity correction sometimes involves long posterior pedicle screw constructs extending from the lumbosacral spine to the thoracic vertebra. As fusion obliterates motion and places supraphysiological stress on adjacent spinal segments, it is crucial to ascertain the ideal upper instrumented vertebra (UIV) to minimize risk of proximal junctional failure (PJF). The T10 vertebra is often chosen to allow bridging of the thoracolumbar junction into the immobile thoracic vertebrae on the basis that it is the lowest immobile thoracic vertebra strut by the rib cage...
November 14, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27852160/predictors-of-functional-outcomes-in-adults-with-traumatic-spinal-cord-injury-following-inpatient-rehabilitation-a-systematic-review
#13
Faisal AlHuthaifi, Joseph Krzak, Timothy Hanke, Lawrence C Vogel
CONTEXT: Despite functional improvements during rehabilitation, variable functional outcomes were reported when patients with Spinal Cord Injury (SCI) return to society. Higher functioning individuals at discharge can experience a decrease in independent mobility (i.e. Motor Functional Independence Measure (mFIM) Score) by one-year follow-up. However, functional gains after discharge have also been reported and associated with recovery. OBJECTIVE: To identify, categorize and rank predictors of mFIM score for patients with SCI following inpatient rehabilitation, both at the time of discharge and at one-year follow-up...
November 17, 2016: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/27847720/dilemmas-of-korean-athletes-with-a-spinal-cord-injury-to-participate-in-sports-a-survey-based-on-the-icf-core-set-for-spinal-cord-injury
#14
Je Shik Nam, Ko Eun Lee, Ah Young Jun, Chong Suck Parke, Hyun Young Kim, You Hyeon Chae
OBJECTIVE: To explore the experiences of athletes with spinal cord injury (SCI) in Korea with respect to dilemmas of participating in sports with regards to the facilitators and barriers, using the International Classification of Functioning, Disability and Health (ICF). METHODS: The facilitators and barriers to sports participation of individuals with SCI were examined using 112 ICF categories. A questionnaire in dichotomous scale was answered, which covered the subjects 'Body functions', 'Body structures', 'Activity and participation' and 'Environmental factors'...
October 2016: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/27845357/participation-in-activities-and-secondary-health-complications-among-persons-aging-with-traumatic-spinal-cord-injury
#15
U Lundström, K Wahman, Å Seiger, D B Gray, G Isaksson, M Lilja
STUDY DESIGN: Cross-sectional study. OBJECTIVES: To describe participation in activities and explore the relationship with secondary complications among persons aging with a traumatic spinal cord injury (SCI). SETTING: A regional SCI outpatient center in Sweden. METHODS: Data were collected through a phone survey, which included 10 activities from the instrument PARTS/M-v3 (PARTicipation Survey/Mobility version-3) together with data from the participants' medical records...
November 15, 2016: Spinal Cord
https://www.readbyqxmd.com/read/27830949/motor-control-exercises-of-the-lumbar-pelvic-region-improve-respiratory-function-in-obese-men-a-pilot-study
#16
Emanuela Bezzoli, Dianne Andreotti, Lucia Pianta, Martina Mascheroni, Lorena Piccinno, Luca Puricelli, Veronica Cimolin, Alberto Salvadori, Franco Codecasa, Paolo Capodaglio
PURPOSE: Obese subjects have decreased pulmonary function. The hypothesis of our study was that poor coordination of the lumbar-pelvic musculature secondary to obesity may hinder the synergic activation of the respiratory muscles. The aim of the paper was to evaluate whether specific motor control exercises of the lumbar-pelvic musculature were able to improve respiratory function. METHOD: Twenty obese male patients underwent a rehabilitation program including adapted physical activity and respiratory physiotherapy...
November 10, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27809702/effects-of-activity-based-therapy-interventions-on-mobility-independence-and-quality-of-life-for-people-with-spinal-cord-injuries-a-systematic-review-and-meta-analysis
#17
Camila Quel de Oliveira, Kathryn Refshauge, James Middleton, Lysanne de Jong, Glen Davis
The aim of this study was to review the literature about the effects of Activity-based therapy (ABT) interventions on mobility, functional independence and quality of life for people with a spinal cord injury (SCI). A systematic review with meta-analysis of randomised and non-randomised trials was performed, including adults with a non-progressive SCI at any level. The intervention of interest was ABT defined as any intervention that sought to improve muscle activation or sensory function below the level of injury in the spinal cord and does not rely on compensatory mechanisms for improving function...
November 3, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27807115/subclassification-of-gmfcs-level-5-cerebral-palsy-as-a-predictor-of-complications-and-health-related-quality-of-life-after-spinal-arthrodesis
#18
Amit Jain, Paul D Sponseller, Suken A Shah, Amer Samdani, Patrick J Cahill, Burt Yaszay, Dolores B Njoku, Mark F Abel, Peter O Newton, Michelle C Marks, Unni G Narayanan
BACKGROUND: The Gross Motor Function Classification System (GMFCS) of cerebral palsy categorizes patients by mobility. Patients at GMFCS level 5 are considered the most disabled and at high risk of hip and spine problems, yet they represent a wide spectrum of function. Our aim was to subclassify patients at GMFCS level 5 who underwent spinal arthrodesis on the basis of central neuromotor impairments and to assess whether subclassification predicted postoperative complications and changes in health-related quality of life...
November 2, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27803139/physical-function-and-spinal-mobility-remain-stable-despite-radiographic-spinal-progression-in-patients-with-ankylosing-spondylitis-treated-with-tnf-%C3%AE-inhibitors-for-up-to-10-years
#19
Denis Poddubnyy, Aleksandra Fedorova, Joachim Listing, Hildrun Haibel, Xenofon Baraliakos, Jürgen Braun, Joachim Sieper
OBJECTIVE: The aim of the study was to investigate the effect of radiographic spinal progression and disease activity on function and spinal mobility in patients with ankylosing spondylitis (AS) treated with tumor necrosis factor-α (TNF-α) inhibitors for up to 10 years. METHODS: Patients with AS who participated in 2 longterm open-label extensions of clinical trials with TNF-α inhibitors (43 receiving infliximab and 17 receiving etanercept) were included in this analysis based on the availability of spinal radiographs performed at baseline and at a later timepoint (yr 2, 4, 6, 8, and 10) during followup...
December 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27800698/on-the-importance-of-3d-geometrically-accurate-and-subject-specific-finite-element-analysis-for-evaluation-of-in-vivo-soft-tissue-loads
#20
Kevin M Moerman, Marc van Vijven, Leandro R Solis, Eline E van Haaften, Arjan C Y Loenen, Vivian K Mushahwar, Cees W J Oomens
Pressure ulcers are a type of local soft tissue injury due to sustained mechanical loading and remain a common issue in patient care. People with spinal cord injury (SCI) are especially at risk of pressure ulcers due to impaired mobility and sensory perception. The development of load improving support structures relies on realistic tissue load evaluation e.g. using finite element analysis (FEA). FEA requires realistic subject-specific mechanical properties and geometries. This study focuses on the effect of geometry...
November 1, 2016: Computer Methods in Biomechanics and Biomedical Engineering
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