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https://www.readbyqxmd.com/read/28227415/ultrasound-transducer-positioning-aid-for-fetal-heart-rate-monitoring
#1
Paul Hamelmann, Alex Kolen, Lars Schmitt, Rik Vullings, Hans van Assen, Massimo Mischi, Libertario Demi, Judith van Laar, Jan Bergmans, Paul Hamelmann, Alex Kolen, Lars Schmitt, Rik Vullings, Hans van Assen, Massimo Mischi, Libertario Demi, Judith van Laar, Jan Bergmans, Alex Kolen, Judith Van Laar, Paul Hamelmann, Libertario Demi, Lars Schmitt, Rik Vullings, Hans Van Assen, Massimo Mischi, Jan Bergmans
Fetal heart rate (fHR) monitoring is usually performed by Doppler ultrasound (US) techniques. For reliable fHR measurements it is required that the fetal heart is located within the US beam. In clinical practice, clinicians palpate the maternal abdomen to identify the fetal presentation and then the US transducer is fixated on the maternal abdomen where the best fHR signal can be obtained. Finding the optimal transducer position is done by listening to the strength of the Doppler audio output and relying on a signal quality indicator of the cardiotocographic (CTG) measurement system...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227331/assessing-the-development-of-fetal-myocardial-function-by-a-novel-doppler-myocardial-performance-index
#2
Ahsan H Khandoker, F Marzbanrad, Y Kimura, Saeed Al Nuaimi, M Palaniswami, Ahsan H Khandoker, F Marzbanrad, Y Kimura, Saeed Al Nuaimi, M Palaniswami, Ahsan H Khandoker, Y Kimura, Saeed Al Nuaimi, F Marzbanrad, M Palaniswami
Doppler-derived myocardial performance index are used to assess aspects of systolic and diastolic function in adult as well as fetal heart. The Tei Index (TI) is a useful and non-invasive tool. The aim of this study was to determine normal values of fetal left ventricular (LV) TI in early (16-32 weeks) and late trimester (35-41 weeks) fetuses and to develop a new myocardial performance index (K-index; KI) which focuses on fetal diastolic interval when oxygenated blood from the placenta filled in the LV. Simultaneous recordings of Doppler Ultrasound Signal (DUS) of the LV outflow tracts and fetal electrocardiogram signals were obtained in 55 early- and late-trimester fetuses...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227288/baseline-fetal-heart-rate-analysis-eleven-automatic-methods-versus-expert-consensus
#3
Agathe Houze de l'Aulnoit, Samuel Boudet, Romain Demailly, Laurent Peyrodie, Regis Beuscart, Denis Houze de l'Aulnoit, Agathe Houze de l'Aulnoit, Samuel Boudet, Romain Demailly, Laurent Peyrodie, Regis Beuscart, Denis Houze de l'Aulnoit, Regis Beuscart, Laurent Peyrodie, Romain Demailly, Samuel Boudet
Visual analysis of fetal heart rate (FHR) during labor is subject to inter- and intra-observer variability that is particularly troublesome for anomalous recordings. Automatic FHR analysis has been proposed as a promising way to reduce this variability. The major difficulty with automatic analysis is to determine the baseline from which accelerations and decelerations will be detected. Eleven methods for automatic FHR analysis were reprogrammed using description from the literature and applied to 66 FHR recordings collected during the first stage of delivery...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227138/assessment-of-autonomic-neurodevelopment-in-the-mouse-fetuses-by-using-fetal-electrocardiography
#4
Ahsan H Khandoker, Thuraia Al Khoori, Takuya Ito, Rika Sugibayashi, Yoshitaka Kimura, Ahsan H Khandoker, Thuraia Al Khoori, Takuya Ito, Rika Sugibayashi, Yoshitaka Kimura, Thuraia Al Khoori, Yoshitaka Kimura, Rika Sugibayashi, Takuya Ito, Ahsan H Khandoker
Fetal Electrocardiography (FECG) offers unique capabilities for assessment of beat-to-beat fetal heart rate (FHR) and fetal heart rate variability (FHRV), which are indirect markers of autonomic nervous system, its development. In this study the fetal ECG signals, FHR and FHRV are successfully recorded to assess the neurodevelopment in fetal mice in the second and third trimester from days 12.5 to 18.5 by using direct insertion of fetal ECG electrodes in the uterine. FHR increases from day 12.5 till 15.5 reaching a plateau and then shows a sudden increase on the day 18...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227137/selective-heart-rate-variability-analysis-to-account-for-uterine-activity-during-labor-and-improve-classification-of-fetal-distress
#5
G J J Warmerdam, R Vullings, J O E H Van Laar, M B Van der Hout-Van der Jagt, J W M Bergmans, L Schmitt, S G Oei, G J J Warmerdam, R Vullings, J O E H Van Laar, M B Van der Hout-Van der Jagt, J W M Bergmans, L Schmitt, S G Oei, M B Van Der Hout-Van Der Jagt, R Vullings, S G Oei, J O E H Van Laar, J W M Bergmans, G J J Warmerdam, L Schmitt
Cardiotocography (CTG) is currently the most often used technique for detection of fetal distress. Unfortunately, CTG has a poor specificity. Recent studies suggest that, in addition to CTG, information on fetal distress can be obtained from analysis of fetal heart rate variability (HRV). However, uterine contractions can strongly influence fetal HRV. The aim of this study is therefore to investigate whether HRV analysis for detection of fetal distress can be improved by distinguishing contractions from rest periods...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226646/comparison-of-data-mining-techniques-applied-to-fetal-heart-rate-parameters-for-the-early-identification-of-iugr-fetuses
#6
G Magenes, R Bellazzi, A Malovini, M G Signorini, G Magenes, R Bellazzi, A Malovini, M G Signorini, R Bellazzi, M G Signorini, G Magenes, A Malovini
The onset of fetal pathologies can be screened during pregnancy by means of Fetal Heart Rate (FHR) monitoring and analysis. Noticeable advances in understanding FHR variations were obtained in the last twenty years, thanks to the introduction of quantitative indices extracted from the FHR signal. This study searches for discriminating Normal and Intra Uterine Growth Restricted (IUGR) fetuses by applying data mining techniques to FHR parameters, obtained from recordings in a population of 122 fetuses (61 healthy and 61 IUGRs), through standard CTG non-stress test...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225422/clinical-updates-in-women-s-health-care-summary-structural-heart-disease-primary-and-preventive-care-review
#7
Tiberio Frisoli, Michele Doughty Voeltz
Reproductive-aged women with structural heart disease who become pregnant as well as postreproductive-aged women with this condition represent a significant proportion of patients seen by obstetrician- gynecologists. Usually, their conditions are complex, and a basic knowledge of the anatomy and physiology of the heart is required. Additionally, understanding the effect of pregnancy on women with structural heart disease is critically important to optimizing maternal and fetal outcomes. This monograph addresses the pathophysiology, signs and symptoms, screening and diagnosis, basic management, and suggested counseling for an obstetric-gynecologic patient with structural heart disease...
March 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28224745/the-effect-of-maternal-low-flow-oxygen-administration-during-the-second-stage-of-labour-on-umbilical-cord-artery-ph-a-randomised-controlled-trial
#8
G Qian, X Xu, L Chen, S Xia, A Wang, Y Chuai, W Jiang
OBJECTIVE: To assess the effect of maternal low flow oxygen administration during the second stage of labour on umbilical cord artery pH. DESIGN: A randomised controlled trial. SETTING: A tertiary teaching hospital in China. POPULATION: Women in the second stage of labour with no complications. METHODS: About 443 women were randomly allocated to receive either supplemental oxygen at a flow rate of 2 l/min or a sham supplementation by nasal cannula...
March 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28222901/pharmacotherapy-in-smoking-cessation-corticotropin-releasing-factor-receptors-as-emerging-intervention-targets
#9
REVIEW
Ioannis Sotiriou, Kleanthi Chalkiadaki, Christos Nikolaidis, Kyriaki Sidiropoulou, Ekaterini Chatzaki
Smoking represents perhaps the single most important health risk factor and a global contributor to mortality that can unquestionably be prevented. Smoking is responsible for many diseases, including various types of cancer, chronic obstructive pulmonary disease, coronary heart disease, peripheral vascular disease and peptic ulcer, while it adversely affects fetal formation and development. Since smoking habit duration is a critical factor for mortality, the goal of treatment should be its timely cessation and relapse prevention...
February 14, 2017: Neuropeptides
https://www.readbyqxmd.com/read/28219933/akt-signalling-as-a-mediator-of-cardiac-adaptation-to-low-birth-weight
#10
Kimberley Cw Wang, Kimberley J Botting, Song Zhang, Caroline McMillen, Doug A Brooks, Janna L Morrison
Intrauterine insults, such as poor nutrition and placental insufficiency, can alter cardiomyocyte development and this can have significant long-term implications for heart health. Consequently, epidemiological studies have shown that low birth weight babies have an increased risk of death from cardiovascular disease in adult life. In addition, intrauterine growth restriction can result in increased left ventricular hypertrophy, which is the strongest predictor for poor health outcomes in cardiac patients. The mechanisms responsible for these associations are not clear, but a suboptimal intrauterine environment can program alternative expression of genes such as cardiac IGF-2/H19, IGF-2R and AT1R through either an increase or decrease in DNA methylation or histone acetylation at specific loci...
February 20, 2017: Journal of Endocrinology
https://www.readbyqxmd.com/read/28217832/gestational-protein-restriction-study-of-the-probable-effects-on-cardiac-muscle-structure-and-function-in-adult-rats
#11
Mona G Amer, Nader M Mohamed, Aly A M Shaalan
Intrauterine growth restriction (IUGR) has been linked to heart disease in adulthood. This study aimed to examine the effect of gestational protein restriction during fetal and early postnatal life on the cardiac muscle structure and function in adult offspring. Pregnant female rats were randomly divided into two dietary groups: normal-protein diet (NP) and low-protein diet (LP). Fifteen male offspring from each group were included in the study. Offspring body weights were recorded at birth and monthly from weaning until 24 weeks of age while systolic blood pressure was measured weekly...
February 20, 2017: Histology and Histopathology
https://www.readbyqxmd.com/read/28217680/first-reported-case-of-fetal-aortic-valvuloplasty-in-asia
#12
Sun-Young Yoon, Hye-Sung Won, Mi-Young Lee, Min Kyong Cho, Euiseok Jung, Ki-Soo Kim, Young-Hwue Kim
Prenatal intervention of severe fetal aortic valve stenosis by ultrasound-guided percutaneous balloon valvuloplasty has been performed to prevent the progression to hypoplastic left heart syndrome, and achieve biventricular circulation in neonates. Here we report a case of fetal aortic valvuloplasty prenatally diagnosed with aortic stenosis at 24 weeks of gestation and showed worsening features on a follow-up echocardiography. Prenatal aortic valvuloplasty was performed at 29 weeks of gestation, and was a technical success...
January 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28216258/review-systematic-review-of-the-utility-of-the-fetal-cerebroplacental-ratio-measured-at-term-for-the-prediction-of-adverse-perinatal-outcome
#13
REVIEW
Liam Dunn, Helen Sherrell, Sailesh Kumar
AIM: This systematic review evaluates the utility of the fetal cerebroplacental ratio (CPR) when assessed at term (from 37 + 0 weeks gestation) as a predictor of adverse obstetric and perinatal outcomes. DATA SOURCES AND SEARCH STRATEGY: An electronic search of Pubmed and Embase using variations of 'cerebroplacental ratio' and 'cerebroumbilical ratio' was conducted by two independent reviewers. Full text studies written in English that reported on low CPR and its correlation with relevant obstetric and perinatal outcomes were included...
February 12, 2017: Placenta
https://www.readbyqxmd.com/read/28215689/histomorphometry-of-the-placental-vasculature-and-microcotyledons-in-thoroughbred-mares-with-chronic-laminitis
#14
Fernanda M Pazinato, Bruna da Rosa Curcio, Cristina G Fernandes, Carlos A Santos, Lorena S Feijó, Antonio Sérgio Varela, Carlos E W Nogueira
The objective of this study was to assess the placental vasculature and microcotyledons in pregnant mares with chronic laminitis. Twenty-six pregnant mares were enrolled in the study, 13 had chronic laminitis (Laminitis Group) and 13 were healthy mares (Healthy Group). Arterial systolic pressure and heart rate were measured in the last 30 days of gestation. After foaling, the fetal membranes were grossly evaluated and samples were harvested for histopathologic examination. All mares had digitalized images taken from chorioallantois for histomorphometry analyses (software-NIH ImageJ)...
March 15, 2017: Theriogenology
https://www.readbyqxmd.com/read/28215417/prenatal-diagnosis-of-the-criss-cross-heart
#15
Prasad Ravi, Deborah Fruitman, Lindsay Mills, Timothy Colen, Lisa K Hornberger
We sought to describe the prenatal features and postnatal outcomes of the "criss-cross heart" (CCH) with crossing atrioventricular connections as encountered in 5 cases and to review the literature regarding fetal diagnoses of this lesion. We reviewed the clinical history and fetal echocardiograms of 5 patients with a diagnosis of CCH encountered in our institution from 2010 to 2015. Affected pregnancies were identified through the University of Alberta fetal cardiology database. Fetal and postnatal echocardiograms, prenatal and postnatal clinical records, autopsy, and surgical reports were reviewed...
December 18, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/28215301/neurotrophic-factors-and-maternal-nutrition-during-pregnancy
#16
M Dhobale
Maternal nutrition is one of the major determinants of pregnancy outcome. It has been suggested that reduced intakes or lack of specific nutrients during pregnancy influences the length of gestation, proper placental and fetal growth during pregnancy. Maternal nutrition, particularly micronutrients such as folate and vitamin B12, and long-chain polyunsaturated fatty acids (LCPUFA) are the major determinants of the one carbon cycle and are suggested to be at the heart of intrauterine programming of diseases in adult life...
2017: Vitamins and Hormones
https://www.readbyqxmd.com/read/28214892/baicalin-attenuates-cardiac-dysfunction-and-myocardial-remodeling-in-a-chronic-pressure-overload-mice-model
#17
Yanqing Zhang, Pingping Liao, Meng'en Zhu, Wei Li, Dan Hu, Siming Guan, Long Chen
BACKGROUND/AIMS: Baicalin has been shown to be effective for various animal models of cardiovascular diseases, such as pulmonary hypertension, atherosclerosis and myocardial ischaemic injury. However, whether baicalin plays a role in cardiac hypertrophy remains unknown. Here we investigated the protective effects of baicalin on cardiac hypertrophy induced by pressure overload and explored the potential mechanisms involved. METHODS: C57BL/6J-mice were treated with baicalin or vehicle following transverse aortic constriction or Sham surgery for up to 8 weeks, and at different time points, cardiac function and heart size measurement and histological and biochemical examination were performed...
February 16, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28212445/long-term-effects-of-fetal-undernutrition-on-rat-heart-role-of-hypertension-and-oxidative-stress
#18
Pilar Rodríguez-Rodríguez, Angel L López de Pablo, Concha F García-Prieto, Beatriz Somoza, Begoña Quintana-Villamandos, José J Gómez de Diego, Perla Y Gutierrez-Arzapalo, David Ramiro-Cortijo, M Carmen González, Silvia M Arribas
BACKGROUND AND AIMS: Fetal undernutrition is a risk factor for heart disease in both genders, despite the protection of women against hypertension development. Using a rat model of maternal undernutrition (MUN) we aimed to assess possible sex differences in the development of cardiac alterations and the implication of hypertension and cardiac oxidative stress. METHODS: Male and female offspring from rats fed ad libitum (control) or with 50% of the normal daily intake during the second half of gestation (MUN) were used...
2017: PloS One
https://www.readbyqxmd.com/read/28211989/timothy-syndrome-1-genotype-without-syndactyly-and-major-extracardiac-manifestations
#19
Róbert Sepp, Lidia Hategan, Attila Bácsi, Judit Cseklye, László Környei, János Borbás, Márta Széll, Tamás Forster, István Nagy, Zoltán Hegedűs
Timothy syndrome 1 (TS1) is a rare genetic disorder characterized by multisystem abnormalities including QT prolongation, congenital heart defects, facial dysmorphism, episodic hypoglycemia, and neurological symptoms. A morphological hallmark of TS1 is syndactyly, present in all cases. TS1 is caused by the canonical p.Gly406Arg mutation in the alternatively spliced exon 8A in the CACNA1C gene, encoding for the main cardiac L-type calcium channel. A variant case of TS1 is reported. The proband had intermittent fetal bradycardia with heart rate of 72 bpm...
March 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28210991/extraction-of-fetal-ecg-signal-by-an-improved-method-using-extended-kalman-smoother-framework-from-single-channel-abdominal-ecg-signal
#20
D Panigrahy, P K Sahu
This paper proposes a five-stage based methodology to extract the fetal electrocardiogram (FECG) from the single channel abdominal ECG using differential evolution (DE) algorithm, extended Kalman smoother (EKS) and adaptive neuro fuzzy inference system (ANFIS) framework. The heart rate of the fetus can easily be detected after estimation of the fetal ECG signal. The abdominal ECG signal contains fetal ECG signal, maternal ECG component, and noise. To estimate the fetal ECG signal from the abdominal ECG signal, removal of the noise and the maternal ECG component presented in it is necessary...
February 16, 2017: Australasian Physical & Engineering Sciences in Medicine
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