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Parkinson disease exercise

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https://www.readbyqxmd.com/read/29345633/impacts-of-an-exercise-program-and-motivational-telephone-counseling-on-health-related-quality-of-life-in-people-with-parkinson-s-disease
#1
JuHee Lee, MoonKi Choi, Yonju Yoo, Sangwoo Ahn, Justin Y Jeon, Ji Young Kim, Ji Yong Byun
PURPOSE: The purpose of this study was to test the effects of group exercise and telephone counseling on physical and psychosocial health in people with Parkinson's disease (PD). DESIGN: This was a quasiexperimental study with a nonequivalent control group. METHODS: This study took place in Seoul, South Korea. Twenty-two and 20 subjects participated in the intervention and comparison groups, respectively. The intervention group performed group exercises twice a week and received motivational telephone counseling every 2 weeks for 12 weeks...
November 14, 2017: Rehabilitation Nursing: the Official Journal of the Association of Rehabilitation Nurses
https://www.readbyqxmd.com/read/29337023/the-effects-of-functional-training-bicycle-exercise-and-exergaming-on-walking-capacity-of-elderly-with-parkinson-s-disease-a-pilot-randomized-controlled-single-blinded-trial
#2
Daniel Dominguez Ferraz, Karen Valadares Trippo, Gabriel Pereira Duarte, Mansueto Gomes Neto, Kionna Oliveira Bernardes Santos, Jamary Oliveira Filho
OBJECTIVES: To compare the effects of functional training, bicycle exercise and exergaming on walking capacity of elderly with Parkinson disease (PD). DESIGN: A pilot randomized controlled single-blinded trial. SETTING: A State Reference Health Care Centre for Elderly, a public reference outpatient clinic for the elderly. PARTICIPANTS: Sixty-two elderly individuals (≥60 years-old) with idiopathic PD (stage 2 to 3 of modified Hoehn and Yahr) according to the London Brain Bank...
January 11, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29331916/aerobic-exercise-is-more-effective-than-goal-based-exercise-for-the-treatment-of-cognition-in-parkinson-s-disease
#3
Carolina R A Silveira, Eric A Roy, Brittany N Intzandt, Quincy J Almeida
BACKGROUND: Little is known about how different exercise modalities influence cognition in Parkinson's disease (PD). Moreover, the focus of previous investigations on examining the effects of exercise mainly on executive functions and the exclusion of individuals with cognitive impairment may limit the potential to define exercise as a treatment for cognitive decline in PD. OBJECTIVE: The aim of this study was to compare the effects of aerobic and goal-based exercise on five cognitive domains in cognitively normal and impaired individuals with PD...
January 10, 2018: Brain and Cognition
https://www.readbyqxmd.com/read/29310015/balance-and-fear-of-falling-in-subjects-with-parkinson-s-disease-is-improved-after-exercises-with-motor-complexity
#4
Carla Silva-Batista, Daniel M Corcos, Hélcio Kanegusuku, Maria Elisa Pimentel Piemonte, Lilian Teresa Bucken Gobbi, Andrea C de Lima-Pardini, Marco Túlio de Mello, Claudia L M Forjaz, Carlos Ugrinowitsch
Resistance training with instability (RTI) uses exercises with high motor complexity that impose high postural control and cognitive demands that may be important for improving postural instability and fear of falling in subjects with Parkinson's disease (PD). Here, we hypothesized that: 1) RTI will be more effective than resistance training (RT) in improving balance (Balance Evaluation Systems Test [BESTest] and overall stability index [Biodex Balance System®]) and fear of falling (Falls Efficacy Scale-International [FES-I] score) of subjects with Parkinson's disease (PD); and 2) changes in BESTest and FES-I after RTI will be associated with changes in cognitive function (Montreal Cognitive Assessment [MoCA] score - previously published) induced by RTI...
December 28, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29282259/exercise-response-in-parkinson-s-disease-insights-from-a-cross-sectional-comparison-with-sedentary-controls-and-a-per-protocol-analysis-of-a-randomised-controlled-trial
#5
Foteini Mavrommati, Johnny Collett, Marloes Franssen, Andy Meaney, Claire Sexton, Andrea Dennis-West, Jill F Betts, Hooshang Izadi, Marko Bogdanovic, Martin Tims, Andrew Farmer, Helen Dawes
OBJECTIVES: To investigate the acute and adaptation cardiovascular and metabolic training responses in people with Parkinson's disease (pwP). DESIGN: (1) A cross-sectional study of exercise response of pwP compared with sedentary controls and (2) an interventional study of exercise training in pwP. SETTING: Community leisure facilities. PARTICIPANTS: pwP (n=83) and sedentary controls (n=55). INTERVENTIONS: Study 1 included participants from a two-arm-parallel single-blind phase II randomised controlled trial (RCT), that undertook a baseline maximal incremental exercise test and study 2 included those randomised to the exercise group in the RCT, who completed a 6-month weekly exercise programme (n=37)...
December 26, 2017: BMJ Open
https://www.readbyqxmd.com/read/29273705/high-intensity-exercise-acutely-increases-substantia-nigra-and-prefrontal-brain-activity-in-parkinson-s-disease
#6
Neil A Kelly, Kimberly H Wood, Jane B Allendorfer, Matthew P Ford, C Scott Bickel, Jon Marstrander, Amy W Amara, Thomas Anthony, Marcas M Bamman, Frank M Skidmore
BACKGROUND Pathologic alterations in resting-state brain activity patterns exist among individuals with Parkinson's disease (PD). Since physical exercise alters resting-state brain activity in non-PD populations and improves PD symptoms, we assessed the acute effect of exercise on resting-state brain activity in exercise-trained individuals with PD. MATERIAL AND METHODS Resting-state functional magnetic resonance imaging (fMRI) was collected twice for 17 PD participants at the conclusion of an exercise intervention...
December 23, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29260454/neuroprotective-effect-of-treadmill-exercise-possibly-via-regulation-of-lysosomal-degradation-molecules-in-mice-with-pharmacologically-induced-parkinson-s-disease
#7
Dong-Joo Hwang, Jung-Hoon Koo, Ki-Cheon Kwon, Dong-Hoon Choi, Sung-Deuk Shin, Jae-Hoon Jeong, Hyun-Seob Um, Joon-Yong Cho
Dysfunction of mitophagy, which is a selective degradation of defective mitochondria for quality control, is known to be implicated in the pathogenesis of Parkinson's disease (PD). However, how treadmill exercise (TE) regulates mitophagy-related molecules in PD remains to be elucidated. Therefore, we aimed to investigate how TE regulates α-synuclein (α-syn)-induced neurotoxicity and mitophagy-related molecules in the nigro-striatal region of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mice. Our data showed that TE exhibited a significant restoration of tyrosine hydroxylase and motor coordination with suppression of α-syn expression, hallmarks of PD, possibly via up-regulation of lysosomal degradation molecules, LAMP-2 and cathepsin L, with down-regulation of p62, LC3-II/LC3-I ratio, PINK1 and parkin in the substantia nigra of MPTP mice...
December 19, 2017: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/29228079/effect-of-high-intensity-treadmill-exercise-on-motor-symptoms-in-patients-with-de-novo-parkinson-disease-a-phase-2-randomized-clinical-trial
#8
Margaret Schenkman, Charity G Moore, Wendy M Kohrt, Deborah A Hall, Anthony Delitto, Cynthia L Comella, Deborah A Josbeno, Cory L Christiansen, Brian D Berman, Benzi M Kluger, Edward L Melanson, Samay Jain, Julie A Robichaud, Cynthia Poon, Daniel M Corcos
Importance: Parkinson disease is a progressive neurologic disorder. Limited evidence suggests endurance exercise modifies disease severity, particularly high-intensity exercise. Objectives: To examine the feasibility and safety of high-intensity treadmill exercise in patients with de novo Parkinson disease who are not taking medication and whether the effect on motor symptoms warrants a phase 3 trial. Design, Setting, and Participants: The Study in Parkinson Disease of Exercise (SPARX) was a phase 2, multicenter randomized clinical trial with 3 groups and masked assessors...
December 11, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29227709/a-review-study-on-the-beneficial-effects-of-baduanjin
#9
Liye Zou, Zhujun Pan, Albert Yeung, Saira Talwar, Chaoyi Wang, Yang Liu, Yankai Shu, Xiaoan Chen, Garrett Anthony Thomas
AIM: Baduanjin, a Chinese traditional Qigong exercise that focuses on a mind-body integration, is considered to be an effective exercise in promoting health. Thus, we systematically and critically evaluated the emerging literature relating to the effects of Baduanjin on health outcomes. METHODS: We used seven English-language electronic databases for the literature search. At least one health-related parameter was reported in retrievable full-text Baduanjin intervention studies...
December 11, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29207899/effect-of-a-mat-pilates-program-with-theraband%C3%A2-on-dynamic-balance-in-patients-with-parkinson-s-disease-feasibility-study-and-randomized-controlled-trial
#10
Irimia Mollinedo, Jose Maria Cancela, María Helena Vila Suarez
OBJECTIVES: The aim of this study is to assess the effect of a physical exercise program based on Mat Pilates with TheraBand® on the dynamic balance of a sample population diagnosed with Parkinson's Disease (PD). METHOD: After random selection, 26 participants were allocated to a Mat Pilates group or a control group where they performed calisthenics exercises. Both interventions lasted 12 weeks and involved two weekly sessions of 60 minutes. Assessments took place at baseline, 12 weeks after the intervention started and 4 weeks after the intervention was completed using the Body Mass Index (BMI), the Timed Up and Go (TUG) test with Wiva® sensors, the 30 Second Chair Stand test and the Five Times Sit to Stand test...
December 5, 2017: Rejuvenation Research
https://www.readbyqxmd.com/read/29206708/use-of-a-telehealth-system-to-enhance-a-home-exercise-program-for-a-person-with-parkinson-disease-a-case-report
#11
Charlotte A Chatto, Paul T York, Catherine P Slade, Scott M Hasson
BACKGROUND AND PURPOSE: This case addresses feasibility of a home-based telehealth system to enhance home exercise program (HEP) adherence for a patient with Parkinson disease (PD). We describe START-System for Technology-Augmented Rehabilitation and Training-and discuss outcomes after integrating START into the HEP component of an established therapy protocol, Lee Silverman Voice Technique BIG (LSVT BIG). CASE DESCRIPTION: The participant was a 67-year-old woman with PD at Hoehn and Yahr Stage II...
December 1, 2017: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/29204298/treadmill-exercise-improves-motor-dysfunction-and-hyperactivity-of-the-corticostriatal-glutamatergic-pathway-in-rats-with-6-ohda-induced-parkinson-s-disease
#12
Wei Chen, Decai Qiao, Xiaoli Liu, Kaixuan Shi
Hyperactivity in the corticostriatal glutamatergic pathway (CGP) induces basal ganglia dysfunction, contributing to parkinsonian syndrome (PS). Physical exercise can improve PS. However, the effect of exercise on the CGP, and whether this pathway is involved in the improvement of PS, remains unclear. Parkinson's disease (PD) was induced in rats by 6-hydroxydopamine injection into the right medial forebrain bundle. Motor function was assessed using the cylinder test. Striatal neuron (SN) spontaneous and evoked firing activity was recorded, and the expression levels of Cav1...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/29198450/effects-of-exercise-on-non-motor-symptoms-in-parkinson-s-disease
#13
Amy W Amara, Adeel A Memon
Patients with Parkinson's disease experience disabling non-motor symptoms, including autonomic dysfunction, cognitive decline, and sleep disorders. Pharmacologic treatments for these symptoms are often ineffective or have intolerable side effects. Therefore, non-pharmacologic interventions are an attractive alternative. Exercise in particular has the potential to alleviate the progressive impairment related to these non-motor symptoms. In this commentary, we explore available research that addresses the impact of exercise and physical activity on autonomic dysfunction, cognitive impairment, and sleep disorders in Parkinson's disease and suggest areas in need of further study...
November 30, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/29163185/orthostatic-intolerance-in-older-persons-etiology-and-countermeasures
#14
REVIEW
Nandu Goswami, Andrew P Blaber, Helmut Hinghofer-Szalkay, Jean-Pierre Montani
Orthostatic challenge produced by upright posture may lead to syncope if the cardiovascular system is unable to maintain adequate brain perfusion. This review outlines orthostatic intolerance related to the aging process, long-term bedrest confinement, drugs, and disease. Aging-associated illness or injury due to falls often leads to hospitalization. Older patients spend up to 83% of hospital admission lying in bed and thus the consequences of bedrest confinement such as physiological deconditioning, functional decline, and orthostatic intolerance represent a central challenge in the care of the vulnerable older population...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29163139/exercise-induced-neuroprotection-of-the-nigrostriatal-dopamine-system-in-parkinson-s-disease
#15
REVIEW
Lijuan Hou, Wei Chen, Xiaoli Liu, Decai Qiao, Fu-Ming Zhou
Epidemiological studies indicate that physical activity and exercise may reduce the risk of developing Parkinson's disease (PD), and clinical observations suggest that physical exercise can reduce the motor symptoms in PD patients. In experimental animals, a profound observation is that exercise of appropriate timing, duration, and intensity can reduce toxin-induced lesion of the nigrostriatal dopamine (DA) system in animal PD models, although negative results have also been reported, potentially due to inappropriate timing and intensity of the exercise regimen...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29158667/different-protocols-for-analyzing-behavior-and-adaptability-in-obstacle-crossing-in-parkinson-s-disease
#16
REVIEW
Nafiseh Mollaei, Estela Bicho, Nuno Sousa, Miguel Fernandes Gago
Imbalance and tripping over obstacles as a result of altered gait in older adults, especially in patients with Parkinson's disease (PD), are one of the most common causes of falls. During obstacle crossing, patients with PD modify their behavior in order to decrease the mechanical demands and enhance dynamic stability. Various descriptions of dynamic traits of gait that have been collected over longer periods, probably better synthesize the underlying structure and pattern of fluctuations in gait and can be more sensitive markers of aging or early neurological dysfunction and increased risk of falls...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29103050/motivators-and-barriers-to-exercise-in-parkinson-s-disease
#17
Mitra Afshari, Amy Yang, Danny Bega
BACKGROUND: Despite evidence for the benefits of exercise in Parkinson's disease (PD), many patients remain sedentary for undefined reasons. OBJECTIVE: To compare exercise habits, perceptions about exercise, and barriers to exercise in 'low' (<3 h/week) and 'high' (≥3 h/week) exercisers with PD. METHODS: A 48-item survey was administered to PD patients at an outpatient academic center. Chi-squared tests were used to compare the percentage differences between low- and high-exercisers with two-sided tests and a significant level of 0...
2017: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/29096672/the-effects-of-yoga-versus-stretching-and-resistance-training-exercises-on-psychological-distress-for-people-with-mild-to-moderate-parkinson-s-disease-study-prxotocol-for-a-randomized-controlled-trial
#18
JoJo Yan Yan Kwok, Jackie Cheuk Yin Kwan, Man Auyeung, Vincent Chung Tong Mok, Helen Yue Lai Chan
BACKGROUND: Psychological distress is prevalent among people with Parkinson's disease (PD) and aggravates their motor symptoms, thereby leading to increased disability, high healthcare costs, and poor health-related quality of life (HRQoL). The under-recognition and adverse effects of the pharmacological management of anxiety and depression among the PD population are considerable. Thus, adopting a Complementary and Alternative Management (CAM) approach to address this problem is important...
November 2, 2017: Trials
https://www.readbyqxmd.com/read/29095706/trunk-exercises-improve-gait-symmetry-in-parkinson-disease-a-blind-phase-ii-randomised-controlled-trial
#19
Ryan P Hubble, Geraldine Naughton, Peter A Silburn, Michael H Cole
OBJECTIVE: Deficits in step-to-step symmetry and trunk muscle activations have been linked to falls in Parkinson's disease (PD). Given such symptoms are poorly managed with anti-parkinsonian medications, alternate therapies are needed. This blind phase II randomised-controlled trial sought to establish whether exercise can improve step-to-step symmetry in PD. DESIGN: Twenty-four PD patients with a falls history completed baseline assessments of symptom severity, balance confidence, mobility and quality of life...
November 1, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29060542/posturography-stability-score-generation-for-stroke-patient-using-kinect-fuzzy-based-approach
#20
Oishee Mazumder, Kingshuk Chakravarty, Debatri Chatterjee, Aniruddha Sinha, Abhijit Das
Aim of this paper is to formulate a posturography stability score for stroke patients using fuzzy logic. Postural instability is one of the prominent symptoms of stroke, dementia, parkinsons disease, myopathy, etc. and is the major precursor of fall. Conventional scoring techniques used to assess postural stability require manual intervention and are dependent on live interaction with physiotherapist. We propose a novel scoring technique to calculate static stability of a person using posturography features acquired by Kinect sensor, which do not require any manual intervention or expert guidance, is cost effective and hence are ideal for tele rehabilitation purpose...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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