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Parkinson disease exercise

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https://www.readbyqxmd.com/read/29791244/the-need-for-mapping-personal-goals-to-exercise-dosage-in-community-based-exercise-programs-for-people-with-parkinson-s-disease
#1
Allison L Amateis, Chelsea L Boesel, Bryan P Ehnert, Abby S Evans, Katheryn E Hurst, Katie L Marek, Amanda C Sullivan, Kathryn R Zalewski, Wendy E Huddleston
PURPOSE: Community-based exercise can support long-term management of Parkinson's disease, although it is not known if personal goals are met in these programs. The objectives of this study were to: (1) examine the goals of community based exercise programs from the participant and instructor perspectives; (2) establish the extent to which these programs meet self-described exercise outcomes; and (3) explore participant and instructor perspectives on barriers to meeting exercise expectations...
May 23, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29785199/physical-exercise-for-parkinson-s-disease-clinical-and-experimental-evidence
#2
REVIEW
Alessandro Oliveira de Carvalho, Alberto Souza Sá Filho, Eric Murillo-Rodriguez, Nuno Barbosa Rocha, Mauro Giovanni Carta, Sergio Machado
Background: National projections about the increase in the elderly population over 60 years bring with it an increase in the number of people affected by Parkinson's Disease (PD), making it an important public health problem. Therefore, the establishment of effective strategies for intervention in people with PD needs to be more clearly investigated. Objective: The study aimed to report the effectiveness of exercise on functional capacity and neurobiological mechanisms in people with PD...
2018: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/29779721/evaluation-of-an-ontology-based-system-for-computerized-cognitive-rehabilitation
#3
Anna Alloni, Silvana Quaglini, Silvia Panzarasa, Elena Sinforiani, Sara Bernini
OBJECTIVES: This paper describes the results of a randomized clinical trial about the effectiveness of a computerized rehabilitation treatment on a sample of 31 patients affected by Parkinson disease. METHODS: Computerized exercises were administered by the therapists to the intervention group (n = 17) through the CoRe tool, which automatically generates a big variety of exercises leveraging on a stimuli set (words, sounds and images) organized into a dedicated ontology...
July 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29754837/effects-of-exercise-on-gait-and-motor-imagery-in-people-with-parkinson-disease-and-freezing-of-gait
#4
Peter S Myers, Marie E McNeely, Kristen A Pickett, Ryan P Duncan, Gammon M Earhart
INTRODUCTION: Exercise improves gait in Parkinson disease (PD), but whether exercise differentially affects people with PD with (freezers) and without freezing of gait (non-freezers) remains unclear. This study examines exercise's effects on gait performance, neural correlates related to these effects, and potential neural activation differences between freezers and non-freezers during motor imagery (MI) of gait. METHODS: Thirty-seven participants from a larger exercise intervention completed behavioral assessments and functional magnetic resonance imaging (fMRI) scans before and after a 12-week exercise intervention...
May 8, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29753113/cardiovascular-responses-during-resistance-exercise-in-patients-with-parkinson-disease
#5
Roberto Miyasato, Carla Silva-Batista, Tiago Peçanha, David A Low, Marco T de Mello, Maria E Piemonte, Carlos Ugrinowitsch, Cláudia L M Forjaz, Hélcio Kanegusuku
BACKGROUND: Patients with Parkinson disease (PD) present cardiovascular autonomic dysfunction which impairs blood pressure control. However, cardiovascular responses during resistance exercise are unknown in these patients. OBJECTIVE: Investigate the cardiovascular responses during resistance exercise performed with different muscle masses, in patients with PD. DESIGN: Two groups, repeated-measures design. SETTING: Exercise Hemodynamic Laboratory, School of Physical Education and Sport, University of São Paulo...
May 9, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29746848/nitric-oxide-alterations-in-cardiovascular-system-of-rats-with-parkinsonism-induced-by-6-ohda-and-submitted-to-previous-exercise
#6
Lorena de Jager, Eric Diego Turossi Amorim, Bruno Fernando Cruz Lucchetti, Fernanda Novi Cortegoso Lopes, Carlos Cesar Crestani, Phileno Pinge-Filho, Marli Cardoso Martins-Pinge
Studies showed that physical exercise decreases the risk of developing Parkinson's disease (PD) as slowing its progression. During aerobic training, nitric oxide (NO) increases in the substantia nigra pars compacta (SNpc) of individuals with PD. However, no study has evaluated the effects of exercise on peripheral NO levels and its modulatory effects on cardiovascular dysfunctions of subjects with PD. Trained (T) or sedentary (S) animals underwent stereotactic surgery for bilateral 6-hydroxydopamine (6-OHDA) or vehicle microinfusion (Sham group)...
May 7, 2018: Life Sciences
https://www.readbyqxmd.com/read/29746402/update-in-therapeutic-strategies-for-parkinson-s-disease
#7
Jaime Kulisevsky, Lais Oliveira, Susan H Fox
PURPOSE OF REVIEW: To review recent advances in therapeutics for motor and nonmotor symptoms of Parkinson's disease. RECENT FINDINGS: Neuroprotection remains a large area of investigation with preliminary safety data on alpha synuclein immunotherapy and glucagon-like peptide-1 agonists. Novel Monoamine Oxidase B and Caetchol-O-methyltransferase-inhibitors for motor fluctuations have shown benefit and are recently approved for clinical use. Long-acting amantadine has also been approved to reduce dyskinesia...
May 8, 2018: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29737443/romberg-ratio-coefficient-in-quiet-stance-and-postural-control-in-parkinson-s-disease
#8
Teresa Paolucci, Marco Iosa, Giovanni Morone, Matteo Delle Fratte, Stefano Paolucci, Vincenzo M Saraceni, Ciro Villani
The aim of this study was to determine the function of visual afference in postural control in Parkinson patients. We enrolled 29 patients and 30 healthy controls. The stabilometry test was performed for posture and balance and Romberg ratio coefficients were calculated. In addition, the Berg Balance Scale and the 6-Minute Walking Test were administered to assess balance and functional exercise capacity; the Unified Parkinson's Disease Rating Scale was used to determine the stage of the disease; and the Short Form (SF)-36 Health Survey was given to collect information on quality of life...
May 8, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29729611/accuracy-of-wearable-physical-activity-trackers-in-people-with-parkinson-s-disease
#9
Robyn M Lamont, Hannah L Daniel, Caitlyn L Payne, Sandra G Brauer
INTRODUCTION: The purpose of this study was to determine the accuracy of the Fitbit Charge HR™ and Garmin vívosmart® HR in measuring steps and reflecting intensity of activity in people with Parkinson's disease (PD). METHODS: Thirty-three people with mild-moderate PD performed six, two-minute indoor walks at their self-selected walking pace, and at target cadences of 60, 80, 100, 120 and 140 beats/min. A 500 m outdoor walk with terrain challenges was also performed...
April 24, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29725348/dynamic-neuro-cognitive-imagery-improves-mental-imagery-ability-disease-severity-and-motor-and-cognitive-functions-in-people-with-parkinson-s-disease
#10
Amit Abraham, Ariel Hart, Isaac Andrade, Madeleine E Hackney
People with Parkinson's disease (PD) experience kinesthetic deficits, which affect motor and nonmotor functions, including mental imagery. Imagery training is a recommended, yet underresearched, approach in PD rehabilitation. Dynamic Neuro-Cognitive Imagery (DNI™) is a codified method for imagery training. Twenty subjects with idiopathic PD (Hoehn and Yahr stages I-III) were randomly allocated into DNI training (experimental; n = 10) or in-home learning and exercise program (control; n = 10). Both groups completed at least 16 hours of training within two weeks...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/29707965/an-enriched-environment-ameliorates-oxidative-stress-and-olfactory-dysfunction-in-parkinson-s-disease-with-%C3%AE-synucleinopathy
#11
Soohyun Wi, Jang Woo Lee, MinGi Kim, Chang-Hwan Park, Sung-Rae Cho
Parkinson's disease (PD) features nonmotor symptoms such as olfactory dysfunction referred to as hyposmia, an initial sign of disease progression. Metabolic dysfunction can contribute to neurodegenerative diseases, and various xenobiotics and endogenous compounds are also involved in the pathogenesis of PD. Although aerobic exercise was found to induce preservation or improvement in olfactory function in PD patients in a recent study, the exact underlying mechanism for this effect is not clear. We aimed to investigate the influence of an enriched environment (EE) on olfactory dysfunction especially via metabolic pathways related to detoxification enzymes...
January 1, 2018: Cell Transplantation
https://www.readbyqxmd.com/read/29706993/instrumental-or-physical-exercise-rehabilitation-of-balance-improves-both-balance-and-gait-in-parkinson-s-disease
#12
Marica Giardini, Antonio Nardone, Marco Godi, Simone Guglielmetti, Ilaria Arcolin, Fabrizio Pisano, Marco Schieppati
We hypothesised that rehabilitation specifically addressing balance in Parkinson's disease patients might improve not only balance but locomotion as well. Two balance-training protocols (standing on a moving platform and traditional balance exercises) were assessed by assigning patients to two groups (Platform, n = 15, and Exercises, n = 17). The platform moved periodically in the anteroposterior, laterolateral, and oblique direction, with and without vision in different trials. Balance exercises were based on the Otago Exercise Program...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/29700848/non-pharmacological-therapies-for-sleep-disturbances-in-people-with-parkinson-s-disease-a-systematic-review
#13
REVIEW
JuHee Lee, Yonji Kim, YieLin Kim
AIM: To determine the effectiveness of non-pharmacological therapies for sleep disturbances in people with Parkinson's disease. BACKGROUND: Sleep disturbances, which are common in people with Parkinson's disease, may diminish their quality of life. Non-pharmacological therapies are preferred over pharmacological therapies for improving sleep quality, owing to fewer adverse effects. DESIGN: Systematic literature review. DATA SOURCES: A systematic search of eight databases and hand searching was conducted for papers published between 1 January 1 2000 - 1 January 2016...
April 27, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29697780/new-horizons-in-fall-prevention
#14
Stephen R Lord, Jacqueline C T Close
Falls pose a major threat to the well-being and quality of life of older people. Falls can result in fractures and other injuries, disability and fear and can trigger a decline in physical function and loss of autonomy. This article synthesises recent published findings on fall risk and mobility assessments and fall prevention interventions and considers how this field of research may evolve in the future. Fall risk topics include the utility of remote monitoring using wearable sensors and recent work investigating brain activation and gait adaptability...
April 25, 2018: Age and Ageing
https://www.readbyqxmd.com/read/29690546/a-rationale-for-music-training-to-enhance-executive-functions-in-parkinson-s-disease-an-overview-of-the-problem
#15
Teresa Lesiuk, Jennifer A Bugos, Brea Murakami
Music listening interventions such as Rhythmic Auditory Stimulation can improve mobility, balance, and gait in Parkinson’s Disease (PD). Yet, the impact of music training on executive functions is not yet known. Deficits in executive functions (e.g., attention, processing speed) in patients with PD result in gait interference, deficits in emotional processing, loss of functional capacity (e.g., intellectual activity, social participation), and reduced quality of life. The model of temporal prediction and timing suggests two networks collectively contribute to movement generation and execution: the basal ganglia-thalamocortical network (BGTC) and the cerebellar-thalamocortical network (CTC)...
April 22, 2018: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29673238/association-of-exercise-induced-autophagy-upregulation-and-apoptosis-suppression-with-neuroprotection-against-pharmacologically-induced-parkinson-s-disease
#16
Yong Chul Jang, Dong Joo Hwang, Jung Hoon Koo, Hyun Seob Um, Nam Hee Lee, Dong Cheol Yeom, Youngil Lee, Joon Yong Cho
PURPOSE: We investigated whether treadmill exercise (TE)-induced neuroprotection was associated with enhanced autophagy and reduced apoptosis in a mouse model of pharmacologically induced Parkinson's disease (PD). METHODS: PD was induced via the administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). C57BL/6 male mice were randomly assigned to the following three groups: control (C57BL, n=10), MPTP with probenecid (MPTP/C, n=10), and MPTP/ C plus exercise (MPTP-TE, n=10)...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29667433/association-between-physical-fitness-cardiovascular-risk-factors-and-parkinson-s-disease
#17
Jan Müller, Jonathan Myers
Objective Exercise is a cornerstone of therapy for Parkinson's disease. This study addressed the association between physical fitness and the onset of Parkinson's disease and association with cardiovascular risk factors. Patients and methods Male veterans ( N = 7347, 59.0 ± 11.2 years) from the Veterans Exercise Testing Study cohort were evaluated. Physical fitness was measured objectively by maximal exercise testing. Onset of Parkinson's disease was abstracted from the Veterans Affairs computerized patient records system...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29659739/physical-exercise-improves-aging-related-changes-in-angiotensin-igf-1-sirt-1-sirt3-and-vegf-in-the-substantia-nigra
#18
Ana Muñoz, Clynton L Corrêa, Andrea Lopez-Lopez, Maria A Costa-Besada, Carmen Diaz-Ruiz, Jose L Labandeira-Garcia
Dysregulation of tissue renin-angiotensin system (RAS) is involved in oxidative and inflammatory processes observed in major aging-related diseases, including neurodegenerative diseases such as Parkinson´s disease (PD). Physical exercise has beneficial effects against aging-related changes, dopaminergic neuron vulnerability and PD progression. The present study indicates that sedentary aged rats have an increase in activity of the nigral angiotensin (Ang) II/Ang type 1 receptor (AT1) axis (i.e. the pro-oxidative pro-inflammatory arm), and a decrease in the activity of the RAS protective arm (i...
April 12, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29629527/an-8-week-low-intensity-progressive-cycling-training-improves-motor-functions-in-patients-with-early-stage-parkinson-s-disease
#19
Hsiu Chen Chang, Chin Song Lu, Wei Da Chiou, Chiung Chu Chen, Yi Hsin Weng, Ya Ju Chang
BACKGROUND AND PURPOSE: The effects of high-intensity cycling as an adjuvant therapy for early-stage Parkinson's disease (PD) were highlighted recently. However, patients experience difficulties in maintaining these cycling training programs. The present study investigated the efficacy of cycling at a mild-to-moderate intensity in early-stage PD. METHODS: Thirteen PD patients were enrolled for 16 serial cycling sessions over a 2-month period. Motor function was assessed using the Unified Parkinson's Disease Rating Scale part III (UPDRS III) and Timed Up and Go (TUG) test as primary outcomes...
April 2018: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/29628812/exercise-therapy-for-a-patient-with-parkinson-disease-and-back-pain-a-case-report
#20
Christina L Rosarion
Objective: The purpose of this report is to describe an exercise intervention for an elderly patient with Parkinson disease with a chief complaint of lower back pain. Clinical Features: The patient was an 85-year-old man who had been diagnosed with Parkinson disease and kyphosis. Back pain was preventing him from carrying out activities of daily living. He was referred for physical therapy for treatment to reduce lower back pain and increase function. An initial examination consisted of testing flexibility and range of motion and administering a pain severity scale and a Lower Extremity Functional Index (LEFI); the patient's initial LEFI score was 14/80...
March 2018: Journal of Chiropractic Medicine
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