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fast ultrasound

Elisa Leyva, Agobardo Cárdenas-Chaparro, Silvia E Loredo-Carrillo, Lluvia I López, Fernanda Méndez-Sánchez, Antonio Martínez-Richa
Naphthoquinone amino derivatives exhibit interesting physicochemical properties and a wide range of biological activities with potential medicinal applications. A clean, fast and simple method for the preparation of phenylamino-1,4-naphthoquinones is presented by the reaction of naphthoquinone (NQ) and anilines under ultrasound irradiation (US). Anilino derivatives were synthesized in good yields and shorter reaction times in comparison with the conventional method. This ultrasound procedure can be applied to the preparation of naphthoquinone derivatives with anilines containing electron-donor substituents (2-OMe, 4-OMe, 4-Me and 4-OEt) or halogen or electron-withdrawing substituents (4-F, 4-Cl, 4-Br, 3-F, 3-Cl, 3-Br, 4-Ac)...
March 13, 2018: Molecular Diversity
Jill K Badin, Ayeeshik Kole, Benjamin Stivers, Victor Progar, Anisha Pareddy, Mouhamad Alloosh, Michael Sturek
BACKGROUND: There is a preponderance of evidence implicating diabetes with increased coronary artery disease (CAD) and calcification (CAC) in human patients with metabolic syndrome (MetS), but the effect of diabetes on CAD severity in animal models remains controversial. We investigated whether diabetes exacerbates CAD/CAC and intracellular free calcium ([Ca2+ ]i ) dysregulation in the clinically relevant Ossabaw miniature swine model of MetS. METHODS: Sixteen swine, eight with alloxan-induced diabetes, were fed a hypercaloric, atherogenic diet for 6 months...
March 9, 2018: Journal of Translational Medicine
D J Li, W L Yang, Z Y Wang, W Chen, Q Zhao, Y F Li, R Cui, L Shen, W B Wei
Objective: To compare the significance of contrast-enhanced ultrasound (CEUS) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in the diagnosis of uveal melanoma. Methods: It was a retrospective case series study. Sixty-three cases (63 eyes) of uveal melanoma patients (confirmed by histopathology) who underwent CEUS and DCE-MRI examination at Beijing Tongren Hospital during January 2010 and May 2014 were collected, including 30 males and 33 females, with average age of 47 years (ranged from 27 to 69 years)...
March 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Fabian Sieland, Jenny Schneider, Detlef W Bahnemann
The effects of the particle size distribution on the charge carrier dynamics and the photocatalytic activity of mixed titanium dioxide (TiO2 ) powder samples were investigated in this work. Instead of the synthesis of the small semiconductor particles, the binary particle size distributions of the powders were obtained by mixing commercially available TiO2 powders with different particle sizes. The pure anatase samples (average diameters: 7, 20, and 125 nm, respectively) were created via ultrasound treatment and discreet drying...
March 8, 2018: Physical Chemistry Chemical Physics: PCCP
Rostyslav V Bubnov, Maria V Drahulian, Polina V Buchek, Tamara P Gulko
Background: Liver fibrosis (LF) is a chronic disease, associated with many collateral diseases including reproductive dysfunction. Although the normal liver has a large regenerative capacity the complications of LF could be severe and irreversible. Hormone and sex-related issues of LF development and interactions with male reproductive have not been finally studied. The aim was to study the reproductive function of male rats in experimental CCl4 -induced liver fibrosis rat model, and the capability for restoration of both the liver and male reproduction system...
March 2018: EPMA Journal
Cosmas Mwikirize, John L Nosher, Ilker Hacihaliloglu
PURPOSE: We propose a framework for automatic and accurate detection of steeply inserted needles in 2D ultrasound data using convolution neural networks. We demonstrate its application in needle trajectory estimation and tip localization. METHODS: Our approach consists of a unified network, comprising a fully convolutional network (FCN) and a fast region-based convolutional neural network (R-CNN). The FCN proposes candidate regions, which are then fed to a fast R-CNN for finer needle detection...
March 6, 2018: International Journal of Computer Assisted Radiology and Surgery
Solmaz Karamikamkar, Ehsan Behzadfar, Karen C Cheung
Producing three-dimensional (3-D) multicellular tumor spheroids (TSs) is valuable for characterizing anticancer drugs since they provide a more representative model of the 3-D in vivo tumor than conventional two-dimensional (2-D) monolayer culture. The interaction of tumor cells with the extracellular matrix (ECM) in a 3-D culture environment is more similar to a tumor in vivo than in a 2-D environment; cell-cell and cell-ECM interaction can influence cell behaviour, such as in response to drug treatment. In vitro tumor spheroid models have been developed using microfluidic systems to generate 3-D hydrogel beads containing components of alginate and ECM protein, such as collagen, with high uniformity and throughput...
March 6, 2018: Biomedical Microdevices
Andreas Hjelm Brandt
This PhD project is based on a longstanding collaboration between physicists and engineers from the Center of Fast Ultrasound Imaging (CFU) at the Technical University of Denmark and medical doctors from the department of Radiology at Rigshospitalet. The intent of this cooperation is to validate new ultrasonic methods for future clinical use. 
Study I compares two B-mode ultrasound methods: the new experimental technique Synthetic Aperture Sequential Beam-forming combined with Tissue Harmonic Imaging (SASB-THI), and a conventional technique combined with THI...
March 2018: Danish Medical Journal
Hugo Perazzo, Isabela Benseñor, José Geraldo Mill, Antônio G Pacheco, Maria de Jesus Mendes da Fonseca, Rosane Härter Griep, Paulo Lotufo, Dora Chor
GOALS: To develop a noninvasive algorithm for diagnosis of liver steatosis and to compare its diagnostic value with available predictive models. BACKGROUND: Liver steatosis represents the most frequent liver disease worldwide. STUDY: This cross-sectional study analyzed data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Patients were randomly divided into training (n=6571) and validation (n=3286) cohort. Abdominal ultrasound (US), used to grade steatosis, and overnight fasting blood tests were performed at the same day...
March 2, 2018: Journal of Clinical Gastroenterology
Adrien Besson, Dimitris Perdios, Florian Martinez, Zhouye Chen, Rafael E Carrillo, Marcel Arditi, Yves Wiaux, Jean-Philippe Thiran
Conventional ultrasound (US) image reconstruction methods rely on delay-and-sum (DAS) beamforming, which is a relatively poor solution to the image reconstruction problem. An alternative to DAS consists in using iterative techniques, which require both an accurate measurement model and a strong prior on the image under scrutiny. Toward this goal, much effort has been deployed in formulating models for US imaging, which usually require a large amount of memory to store the matrix coefficients. We present two different techniques, which take advantage of fast and matrix-free formulations derived for the measurement model and its adjoint, and rely on sparsity of US images in well-chosen models...
March 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Colas Schretter, Shaun Bundervoet, David Blinder, Ann Dooms, Jan D'hooge, Peter Schelkens
Upcoming phased-array 2-D sensors will soon enable fast high-definition 3-D ultrasound imaging. Currently, the communication of raw radio-frequency (RF) channel data from the probe to the computer for digital beamforming is a bottleneck. For reducing the amount of transferred data samples, this paper investigates the design of an adapted sparse sampling technique for image reconstruction inspired by the compressed sensing framework. Echo responses from isolated points are generated using a physically based simulation of ultrasound wave propagation through tissues...
March 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Sulan Lin, Yajing Xian, Yi Liu, Wen Cai, Jiangmei Song, Xiangyang Zhang
This study is to investigate the prevalence and risk factors of nonalcoholic fatty liver disease (NAFLD) and to analyze the effect of comprehensive community intervention on NAFLD in community residents in Urumqi, China.Cluster sampling method with street community as a unit was adopted in this study. Questionnaire survey, body measurement, blood biochemistry (including liver function, fasting blood glucose [FPG], and uric acid [UA]) examination as well as liver B ultrasound were performed. Then, comprehensive intervention was conducted in NAFLD patients...
March 2018: Medicine (Baltimore)
Adeleye Dorcas Omisore, Olusola Comfort Famurewa, Morenikeji Adeyoyin Komolafe, Christiana Mopelola Asaleye, Michael Bimbola Fawale, Babalola Ishmael Afolabi
BACKGROUND: Traditional cardiovascular risk factors (CVRFs), which include age, gender, hypertension, diabetes mellitus, dyslipidaemia, smoking, alcohol consumption, chronic kidney disease and obesity, have been shown to be associated with atherosclerosis. We aimed to evaluate the impact of traditional CVRFs on carotid atherosclerosis (CA) in a sample of Nigerian adults. METHODS: We examined 162 subjects with traditional CVRFs in a cross-sectional study. Demographic and clinical data, including history of hypertension, diabetes mellitus, smoking, alcohol intake and chronic kidney disease, as well as systolic and diastolic blood pressure, weight and height were collected...
February 28, 2018: Cardiovascular Journal of Africa
Robert P Jamplis, Lucas Friedman, Srikar Adhikari
A 28-year-old male was brought to the emergency department by the Emergency medical services (EMS) after being found unconscious and unresponsive. Upon arrival, he was hypotensive, intubated with a Glasgow Coma Scale (GCS) 3T, without the signs of trauma or the evidence of bleeding. A focused assessment with sonography in trauma (FAST), point-of-care ultrasound (POCUS) was performed, obscuring part of the spleen from the distended stomach, which was filled with the heterogeneous contents, with the internal movement being identified...
December 17, 2017: Curēus
Arafat Khalphallah, Nasr-Eldin M Aref, Ashraf M Abu-Seida, Enas Elmeligy, Sara A Bayoumi, Al-Lethie A Al-Lethie, Doaa Salman
This study describes the ultrasonographic findings of five hepatobiliary diseases in buffaloes. Fifty buffaloes including; 20 clinically normal and 30 hepatobiliary diseased buffaloes were enrolled in this study. Complete clinical, radiographic and ultrasonographic examinations and laboratory analyses were conducted. RESULTS: Focal parenchymal lesions including liver abscess (N=12) and hepatic cyst (N=6), diffuse parenchymal lesion (hepatobiliary cirrhosis, N=5) and obstruction of hepatobiliary passages including cholestasis (N=4) and hepatocholelithiasis (N=3) were successfully imaged by ultrasound...
February 27, 2018: Journal of Veterinary Science
Helen I Keen, Wendy A Davis, Erin Latkovic, Jocelyn J Drinkwater, Johannes Nossent, Timothy M E Davis
AIMS: The prevalence and consequences (articular and extra-articular) of hyperuricemia in type 2 diabetes, especially when asymptomatic (ASH), are incompletely understood. The aim of this study was to use ultrasonography to assess pathology associated with monosodium urate deposition in the joints of well-characterized hyperuricemic patients with type 2 diabetes. METHODS: A subset of 101 participants (mean age 70.4 years, 59.8% males, median diabetes duration 14...
January 5, 2018: Journal of Diabetes and its Complications
Lorenzo Falsetti, Giovanna Viticchi, Laura Buratti, Francesco Grigioni, Alessandro Capucci, Mauro Silvestrini
BACKGROUND: An association between non-valvular atrial fibrillation (NVAF) and cognitive impairment has been hypothesized. OBJECTIVE: We sought to evaluate whether and how permanent NVAF (pNVAF) is associated with progression of cognitive impairment in patients with Alzheimer's disease (AD) in the presence of vascular or genetic risk factors. METHODS: 310 consecutive patients affected by mild-moderate AD were included and followed for a 24-month period...
2018: Journal of Alzheimer's Disease: JAD
Ilker Ince, Muhammet Ali Arı, Muhammet Mustafa Sulak, Mehmet Aksoy
BACKGROUND AND OBJECTIVES: There are different ultrasound probe positions used for internal jugular venous catheter placement. Also, in-plane or out of plane needle approach may be used for catheterization. Transverse short-axis classic approach is the most popular performed approach in literature. "Syringe-Free" is a new described technique that is performed with oblique long-axis approach. We aimed to compare performance of these two approaches. METHODS: This study was conducted as a prospective and randomized study...
February 22, 2018: Revista Brasileira de Anestesiologia
YanFang Wang, Fang Nie, Ting Liu, Dan Yang, Qi Li, Jing Li, AiLing Song
The use of ultrasound in differentiation of benign and malignant solid hypo-echoic thyroid nodules is a dilemma in clinical practice. The aim of this study was to investigate the revised value of contrast-enhanced ultrasound (CEUS) for differentiating solid hypo-echoic thyroid nodules using the Thyroid Imaging Reporting and Data System (TI-RADS).The study included 135 patients with 135 nodules confirmed by fine-needle aspiration and/or surgery. Every nodule underwent both conventional US and CEUS. Binary logistic regression analysis for conventional US features revealed that irregular shape, microcalcification and height greater than width were significant malignant predictive features...
February 19, 2018: Ultrasound in Medicine & Biology
Luan Geraldo Ocaña Oliveira, Debora Tagliari, Mariana Juliato Becker, Thiago Adame, José Cruvinel Neto, Fernando Antônio Campelo Spencer Netto
OBJECTIVE: to verify the efficiency and usefulness of basic ultrasound training in trauma (FAST - Focused Assessment with Sonography in Trauma) for emergency physicians in the primary evaluation of abdominal trauma. METHODS: a longitudinal and observational study was carried out from 2015 to 2017, with 11 emergency physicians from Hospital Universitário do Oeste do Paraná, submitted to ultrasound training in emergency and trauma (USET® - SBAIT). FAST results started to be collected two months after the course...
February 19, 2018: Revista do Colégio Brasileiro de Cirurgiões
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