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https://www.readbyqxmd.com/read/27919218/a-glycemic-threshold-of-90-mg-dl-promotes-early-signs-of-atherosclerosis-in-apparetly-healthy-overweight-obese-subjects
#1
Marco Matteo Ciccone, Francesca Cortese, Michele Gesualdo, Ilaria Donvito, Santa Carbonara, Giovanni De Pergola
BACKGROUND: Alterations of glucose metabolism represent well known risk factors for the atherosclerotic process and then for cardiovascular disease. OBJECTIVE: to investigate the association between fasting glucose and early signs of atherosclerosis, by means of carotid intima-media thickness (c-IMT) in a population of apparently healthy overweight/obese subjects. In addition, we evaluated the possible existence of a glycemic threshold above which the risk of atherosclerosis significantly increases...
December 5, 2016: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/27917764/diabetic-cachectic-neuropathy-an-uncommon-neurological-complication-of-diabetes
#2
A Iyagba, A Onwuchekwa
A 40-year-old female patient with diabetes of 12 years' duration, with poor drug compliance, presented with a 4-month history of rapid progressive weight loss, burning sensations in the feet, abdominal swelling, and constipation with occasional episodes of epigastric pain. On examination, she was chronically ill-looking with a body mass index of 17.1 kg/m2, grossly distended abdomen (initially mistaken for gravid abdomen). Blood pressure measurements in the supine and standing positions were 200/130 mmHg and 180/100 mmHg, respectively...
December 1, 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/27912784/liraglutide-improves-metabolic-parameters-and-carotid-intima-media-thickness-in-diabetic-patients-with-the-metabolic-syndrome-an-18-month-prospective-study
#3
Manfredi Rizzo, Ali A Rizvi, Angelo Maria Patti, Dragana Nikolic, Rosaria Vincenza Giglio, Giuseppa Castellino, Giovanni Li Volti, Massimiliano Caprio, Giuseppe Montalto, Vincenzo Provenzano, Stefano Genovese, Antonio Ceriello
BACKGROUND: Liraglutide, a GLP-1 analogue, exerts several beneficial non-glycemic effects in patients with type-2 diabetes (T2DM), such as those on body weight, blood pressure, plasma lipids and inflammation markers. However, the effects of liraglutide on cardiovascular (CV) risk markers in subjects with the metabolic syndrome (MetS) are still largely unknown. We herein explored its effects on various cardio-metabolic risk markers of the MetS in subjects with T2DM. METHODS: We performed an 18-month prospective, real-world study...
December 3, 2016: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/27905147/reduced-nondominant-lumbar-multifidi-cross-sectional-area-is-a-precursor-of-low-back-injury-in-cricket-fast-bowlers
#4
B Olivier, N Gillion, A V Stewart, W McKinon
Asymmetry in the lumbar multifidi muscle (LM) cross-sectional area (CSA) is associated with low back injury. The aim of this prospective cohort study was to investigate the symmetry of the CSA of LM at L3, L4, and L5, in the context of simultaneous injury monitoring. Injury free, male, right-handed cricket fast bowlers playing at a nonprofessional level participated in this study. LM CSA at L3, L4, and L5 vertebral levels was measured through the use of ultrasound imaging in prone. The primary outcome measure of the study was the incidence of an injury during a cricket season of eight-month duration...
December 1, 2016: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/27905047/endoscopic-ultrasound-guided-fine-needle-aspiration-biopsy-eus-fna-in-insulinomas-indications-and-clinical-relevance-in-a-single-investigator-cohort-of-47-patients
#5
Peter Herbert Kann, Roland Moll, Detlef Bartsch, Andreas Pfützner, Thomas Forst, Gianluca Tamagno, Joachim N Goebel, Verena Fourkiotis, Simona Raluca Bergmann, Maike Collienne
PURPOSE: This study was aimed to investigate the role and relevance of endoscopic ultrasound-guided fine-needle aspiration biopsy in the diagnostic work-up of insulinomas. METHODS: We have analysed the frequency, clinical indications, success rate (obtaining diagnostic tissue), diagnostic accuracy (in comparison to the pathological diagnosis after surgery), complications, and tolerability of endoscopic ultrasound-guided fine-needle aspiration biopsy and the localization and size of the lesions in 47 consecutive patients (29 females, 18 males; 46 ± 15 years) who had surgery for insulinoma following fasting test and were explored by single investigator EUS 1994-2015...
November 30, 2016: Endocrine
https://www.readbyqxmd.com/read/27901182/does-insulin-resistance-increase-thyroid-volume-in-patients-with-polycystic-ovary-syndrome
#6
Murat Sahin, Didem Demircioglu, Ayten Oguz, Dilek Tuzun, Mehmet Akif Sarica, Elif Inanc, Kamile Gul
Objective: To investigate the effect of gonadotropin, sex hormone levels and insulin resistance (IR) on thyroid functions and thyroid volume (TV) in polycystic ovary syndrome (PCOS). Subjects and methods: 69 new diagnosed PCOS patients (age 24.82 ± 6.17) and 56 healthy control female (age 26.69 ± 5.25) were involved to the study. Fasting plasma glucose, lipid profile, insulin, thyroid stimulating hormone (TSH), free thyroxine (fT4), estradiol (E2), luteinizing hormone (LH), follicle stimulating hormone levels and urine iodine were measured in all participants...
November 24, 2016: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27898380/famus-ii-a-fast-and-mechanistic-ultrasound-simulator-using-an-impulse-response-approach
#7
Luis Aguilar, Justin Wong, David A Steinman, Richard S C Cobbold
Real-time simulation of ultrasound images is increasingly important for providing a means of presenting a wide variety of clinical images for the training of ultrasound specialists and technologists. In order to realistically represent the visual effects caused by changes to the transducer position or its focal properties, very rapid transducer field response calculations are needed, typically on the order of a fraction of a second. Currently available methods are severely limited in this regard. Based on the impulse response, a point source/receiver method for accurately calculating the fields produced by ultrasound transducer arrays is proposed and illustrated with realistic B-mode and Doppler spectral display simulations...
November 24, 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27898043/fast-interrogation-of-fiber-bragg-gratings-with-electro-optical-dual-optical-frequency-combs
#8
Julio E Posada-Roman, Jose A Garcia-Souto, Dragos A Poiana, Pablo Acedo
Optical frequency combs (OFC) generated by electro-optic modulation of continuous-wave lasers provide broadband coherent sources with high power per line and independent control of line spacing and the number of lines. In addition to their application in spectroscopy, they offer flexible and optimized sources for the interrogation of other sensors based on wavelength change or wavelength filtering, such as fiber Bragg grating (FBG) sensors. In this paper, a dual-OFC FBG interrogation system based on a single laser and two optical-phase modulators is presented...
November 26, 2016: Sensors
https://www.readbyqxmd.com/read/27895878/evaluation-of-visibility-of-foreign-bodies-in-the-maxillofacial-region-comparison-of-computed-tomography-cone-beam-computed-tomography-ultrasound-and-magnetic-resonance-imaging
#9
Solmaz Valizadeh, Hamidreza Pouraliakbar, Leila Kiani, Yaser Safi, Leila Alibakhshi
BACKGROUND: Detection of foreign bodies (FBs) is challenging. Selection of a fast and affordable imaging modality to locate the FB with minimal patient radiation dose is imperative. OBJECTIVES: This study sought to compare four commonly used imaging modalities namely cone beam computed tomography (CBCT), magnetic resonance imaging (MRI), computed tomography (CT), and ultrasound (US) for detection of FBs in the head and neck region. MATERIALS AND METHODS: In this in vitro study, iron, glass, stone, wood, asphalt, and tooth samples measuring 0...
October 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27894116/intrarenal-vascular-resistance-is-associated-with-a-prothrombotic-state-in-hypertensive-patients
#10
Cristiana Catena, GianLuca Colussi, Marileda Novello, Valentina Fagotto, Leonardo A Sechi
BACKGROUND/AIMS: Hypertensive nephroangiosclerosis is associated with progressive increase of intrarenal vascular resistance. In addition to blood pressure, other factors can contribute to hypertensive renal damage including a prothrombotic state. We investigated the relationship between hemostatic markers and intrarenal vascular resistance in hypertension. METHODS: In 115 untreated, nondiabetic, hypertensive subjects free of cardiovascular complications and advanced renal function impairment, we measured 24-hour creatinine clearance (GFR) and urinary albumin excretion (UAE), fasting plasma glucose, HOMA-index, and plasma levels of fibrinogen, D-dimer, prothrombin fragment 1+2, plasminogen activator inhibitor-1, homocysteine, and lipoprotein(a)...
November 29, 2016: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/27886149/toward-optimal-computation-of-ultrasound-image-reconstruction-using-cpu-and-gpu
#11
Udomchai Techavipoo, Denchai Worasawate, Wittawat Boonleelakul, Rachaporn Keinprasit, Treepop Sunpetchniyom, Nobuhiko Sugino, Pairash Thajchayapong
An ultrasound image is reconstructed from echo signals received by array elements of a transducer. The time of flight of the echo depends on the distance between the focus to the array elements. The received echo signals have to be delayed to make their wave fronts and phase coherent before summing the signals. In digital beamforming, the delays are not always located at the sampled points. Generally, the values of the delayed signals are estimated by the values of the nearest samples. This method is fast and easy, however inaccurate...
November 24, 2016: Sensors
https://www.readbyqxmd.com/read/27882677/utility-of-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-in-diagnosing-non-specific-inflammatory-intrathorcacic-lymphadenitis
#12
Huizhen Yang, Shenglan Wang, Jiajun Teng, Baohui Han, Jiayuan Sun
BACKGROUND AND OBJECTIVE: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has emerged as a minimally invasive technique for diagnosing intrathoracic malignancies and some benignancies; however, there are no data available on the utility of EBUS-TBNA for the diagnosis of non-specific inflammatory intrathoracic lymphadenitis. METHODS: A prospective analysis was performed from 104 patients with enlarged lymphadenopathy suspected of non-specific lymphadenitis referred for EBUS-TBNA between October 2009 and March 2012...
November 7, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27876143/a-dispersive-liquid-liquid-microextraction-using-a-switchable-polarity-dispersive-solvent-automated-hplc-fld-determination-of-ofloxacin-in-chicken-meat
#13
Irina Timofeeva, Semen Timofeev, Leonid Moskvin, Andrey Bulatov
In this article, dispersive liquid-liquid microextraction (DLLME), based on the use of so-called switchable polarity dispersive solvent (SPDS) for microextraction, is presented for the first time. The new extraction technique makes use of a mixture of extraction solvent (dichloromethane) and the SPDS (acrylic acid). This mixture is injected into the aqueous sample solution, which was previously fortified with the alkaline agent (NaOH). The SPDS is dissolved in aqueous phase and a cloudy solution consisting of fine droplets of extraction solvent fully dispersed in the aqueous phase is observed...
January 1, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/27874191/nitrate-and-nitrite-determination-in-gunshot-residue-samples-by-capillary-electrophoresis-in-acidic-run-buffer
#14
Özge Ö Erol, Behice Y Erdoğan, Atiye N Onar
Simultaneous determination of nitrate and nitrite in gunshot residue has been conducted by capillary electrophoresis using an acidic run buffer (pH 3.5). In previously developed capillary electrophoretic methods, alkaline pH separation buffers were used where nitrite and nitrate possess similar electrophoretic mobility. In this study, the electroosmotic flow has been reversed by using low pH running buffer without any additives. As a result of reversing the electroosmotic flow, very fast analysis has been actualized, well-defined and separated ion peaks emerge in less than 4 min...
November 22, 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27870902/sleep-duration-exercise-shift-work-and-polycystic-ovarian-syndrome-related-outcomes-in-a-healthy-population-a-cross-sectional-study
#15
Audrey J R Lim, Zhongwei Huang, Seok Eng Chua, Michael S Kramer, Eu-Leong Yong
CONTEXT: Few studies have examined the associations between sleep duration, shiftwork, and exercise to the infrequent menstruation, hyperandrogenism, and ovarian morphological changes observed in women with polycystic ovarian syndrome (PCOS). OBJECTIVE: To examine whether lifestyle factors, including short sleep duration, insufficient exercise, and shiftwork, alone or in combination, are associated with the reproductive and metabolic abnormalities typical of PCOS in a healthy population...
2016: PloS One
https://www.readbyqxmd.com/read/27863097/serum-levels-of-endocannabinoids-are-independently-associated-with-nonalcoholic-fatty-liver-disease
#16
Shira Zelber-Sagi, Shahar Azar, Alina Nemirovski, Muriel Webb, Zamir Halpern, Oren Shibolet, Joseph Tam
OBJECTIVE: To evaluate the association between circulating levels of endocannabinoids (eCBs) and non-alcoholic fatty liver disease (NAFLD). METHODS: The serum levels of the main eCBs, anandamide (AEA) and 2-arachidonoylglycerol (2-AG), and their endogenous precursor and breakdown product, arachidonic acid (AA), were analyzed by liquid chromatography/tandem mass spectrometry in 105 volunteers screened for NAFLD. Hepatic ultrasound, fasting blood tests, and anthropometrics were assessed...
November 15, 2016: Obesity
https://www.readbyqxmd.com/read/27854028/impaired-fasting-glucose-and-impaired-glucose-tolerance-in-children-and-adolescents-with-overweight-obesity
#17
P Di Bonito, L Pacifico, C Chiesa, G Valerio, E Miraglia Del Giudice, C Maffeis, A Morandi, C Invitti, M R Licenziati, S Loche, G Tornese, F Franco, M Manco, M G Baroni
OBJECTIVE: To investigate in a large sample of overweight/obese (OW/OB) children and adolescents the prevalence of prediabetic phenotypes such as impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), and to assess their association with cardiometabolic risk (CMR) factors including hepatic steatosis (HS). METHODS: Population data were obtained from the CARdiometabolic risk factors in children and adolescents in ITALY study. Between 2003 and 2013, 3088 youths (972 children and 2116 adolescents) received oral glucose tolerance test (OGTT) and were included in the study...
November 16, 2016: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/27853745/right-adrenal-gland-prospective-evaluation-through-transgastric-endoscopic-ultrasound-an-alternative-approach
#18
Pedro C Figueiredo, Pedro Pinto-Marques, Ines Almeida, Pedro C Gomes, David Serra
Background and aims: Endoscopic ultrasound (EUS) guided right adrenal gland (RAG) evaluation is frequently unsuccessful and, when feasible, requires a cumbersome maneuver through the duodenum. In our experience, the use of a recent ultrasound platform has enabled transgastric detection of the RAG with a simple maneuver. The aim of this study was to determine the RAG transgastric EUS detection rate and identify predictive factors for failure. Methods: Consecutive patients referred to EUS in a single center were prospectively included over a 6-month period...
November 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/27853246/plasma-selenium-levels-and-nonalcoholic-fatty-liver-disease-in-chinese-adults-a-cross-sectional-analysis
#19
Zhen Yang, Chonghuai Yan, Gang Liu, Yixin Niu, Weiwei Zhang, Shuai Lu, Xiaoyong Li, Hongmei Zhang, Guang Ning, Jiangao Fan, Li Qin, Qing Su
Selenium exposure can induce liver insulin resistance and increased liver triglyceride concentrations in animals, which may link to an increased risk of nonalcoholic fatty liver disease (NAFLD). However, epidemiological studies investigating the association between elevated plasma selenium levels and NAFLD were not available. We aimed to investigate the association of selenium levels with the prevalence of NAFLD in Chinese adults. This was a cross-sectional study of 8550 Chinese adults aged 40 yr or older in Shanghai, China...
November 17, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27847852/assessment-of-diagnostic-value-of-single-view-dynamic-technique-in-diagnosis-of-developmental-dysplasia-of-hip-a-comparison-with-static-and-dynamic-ultrasond-techniques
#20
Seyed Ali Alamdaran, Sahar Kazemi, Ali Parsa, Mohammad Hallaj Moghadam, Ali Feyzi, Reza Mardani
BACKGROUND: Developmental dysplasia of hip (DDH) is a common childhood disorder, and ultrasonography examination is routinely used for screening purposes. In this study, we aimed to evaluate a modified combined static and dynamic ultrasound technique for the detection of DDH and to compare with the results of static and dynamic ultrasound techniques. METHODS: In this cross-sectional study, during 2013- 2015, 300 high-risk infants were evaluated by ultrasound for DDH...
October 2016: Archives of Bone and Joint Surgery
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