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https://www.readbyqxmd.com/read/29035338/integrating-medication-therapy-management-mtm-services-provided-by-community-pharmacists-into-a-community-based-accountable-care-organization-aco
#1
Brian Isetts
(1) Background: As the U.S. healthcare system evolves from fee-for-service financing to global population-based payments designed to be accountable for both quality and total cost of care, the effective and safe use of medications is gaining increased importance. The purpose of this project was to determine the feasibility of integrating medication therapy management (MTM) services provided by community pharmacists into the clinical care teams and the health information technology (HIT) infrastructure for Minnesota Medicaid recipients of a 12-county community-based accountable care organization (ACO)...
October 16, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29034440/risperidone-induced-metabolic-dysfunction-is-attenuated-by-curcuma-longa-extract-administration-in-mice
#2
Florent Auger, Françoise Martin, Olivier Pétrault, Jennifer Samaillie, Thierry Hennebelle, Mohamed-Sami Trabelsi, François Bailleul, Bart Staels, Régis Bordet, Patrick Duriez
Antipsychotics, such as risperidone, increase food intake and induce alteration in glucose and lipid metabolism concomitantly with overweight and body fat increase, these biological abnormalities belong to the metabolic syndrome definition (high visceral adiposity, hypertriglyceridemia, hyperglycemia, low HDL-cholesterol and high blood pressure). Curcumin is a major component of traditional turmeric (Curcuma longa) which has been reported to improve lipid and glucose metabolism and to decrease weight in obese mice...
October 16, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/29028545/penicillium-expansum-compatible-and-penicillium-digitatum-non-host-pathogen-infection-differentially-alter-ethylene-biosynthesis-in-apple-fruit
#3
Laura Vilanova, Núria Vall-Llaura, Rosario Torres, Josep Usall, Neus Teixidó, Christian Larrigaudière, Jordi Giné-Bordonaba
The role of ethylene on inducing plant resistance or susceptibility to certain fungal pathogens clearly depends on the plant pathogen interaction with little or no-information available focused on the apple-Penicillium interaction. Taken advantage that Penicillium expansum is the compatible pathogen and P. digitatum is the non-host of apples, the present study aimed at deciphering how each Penicillium spp. could interfere in the fruit ethylene biosynthesis at the biochemical and molecular level. The infection capacity and different aspects related to the ethylene biosynthesis were conducted at different times post-inoculation...
September 30, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29024108/changes-in-hepatic-glucose-and-lipid-metabolism-related-parameters-in-domestic-pigeon-columba-livia-during-incubation-and-chick-rearing
#4
X P Wan, P Xie, Z Bu, X T Zou
This study aimed to evaluate the hepatic glucose and lipid metabolism-related parameters of adult male and female White King pigeons (Columba livia) during incubation and chick rearing. At day 4 (I4), 10 (I10) and 17 (I17) of incubation and day 1 (R1), 7 (R7), 15 (R15) and 25 (R25) of chick rearing, livers were sampled from six pigeons for each sex. Glycogen and fat contents, activities of glycolytic enzymes (hexokinase, HK; 6-phosphofructokinase, 6-PFK), and genes expressions of key enzymes involved in glycolysis (pyruvate kinase, PK; glucokinase, GK), gluconeogenesis (phosphoenolpyruvate carboxykinase cytosolic, PCK1; fructose-1,6-bisphosphatase, FBP1; glucose-6-phosphatase, G6Pase), fatty acid synthesis (fatty acid synthase, FAS; acetyl-CoA carboxylase, ACC) and fatty acid β-oxidation (carnitine palmitoyltransferase 1, CPT1; acyl-CoA 1, ACO) were measured...
October 12, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28989745/spatial-capture-recapture-analysis-of-artificial-cover-board-survey-data-reveals-small-scale-spatial-variation-in-slow-worm-anguis-fragilis-density
#5
Benedikt R Schmidt, Anita Meier, Chris Sutherland, J Andy Royle
Vague and/or ad hoc definitions of the area sampled in monitoring efforts are common, and estimates of ecological state variables (e.g. distribution and abundance) can be sensitive to such specifications. The uncertainty in population metrics due to data deficiencies, vague definitions of space and lack of standardized protocols is a major challenge for monitoring, managing and conserving amphibian and reptile populations globally. This is especially true for the slow-worm (Anguis fragilis), a cryptic and fossorial legless lizard; uncertainty about spatial variation in density has hindered conservation efforts (e...
September 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28988080/flood-susceptibility-mapping-using-novel-ensembles-of-adaptive-neuro-fuzzy-inference-system-and-metaheuristic-algorithms
#6
Seyed Vahid Razavi Termeh, Aiding Kornejady, Hamid Reza Pourghasemi, Saskia Keesstra
Flood is one of the most destructive natural disasters which cause great financial and life losses per year. Therefore, producing susceptibility maps for flood management are necessary in order to reduce its harmful effects. The aim of the present study is to map flood hazard over the Jahrom Township in Fars Province using a combination of adaptive neuro-fuzzy inference systems (ANFIS) with different metaheuristics algorithms such as ant colony optimization (ACO), genetic algorithm (GA), and particle swarm optimization (PSO) and comparing their accuracy...
October 4, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28984496/spending-carveouts-substantially-improve-the-accuracy-of-performance-measurement-in-shared-savings-arrangements-findings-from-simulation-analysis-of-medicaid-acos
#7
Derek DeLia
Accuracy of spending-based provider performance metrics is limited by random variation and components of spending that are uncontrollable by providers. Such components vary according to the care management focus and operational maturity of each provider group. This study uses data from New Jersey Medicaid accountable care organizations (ACOs) to examine how carving out uncontrollable components of spending affects the accuracy of performance measures in shared savings arrangements. Spending on injury care, custodial care in facilities (CCF), and amounts above $100 000 per patient are used as examples of potentially uncontrollable spending...
January 1, 2017: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/28982831/association-of-asthma-chronic-obstructive-pulmonary-disease-overlap-syndrome-with-coronary-artery-disease-cardiac-dysrhythmia-and-heart-failure-a-population-based-retrospective-cohort-study
#8
Jun-Jun Yeh, Yu-Feng Wei, Cheng-Li Lin, Wu-Huei Hsu
OBJECTIVES: Patients with asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS) and cardiovascular diseases (CVDs) share common risk factors. However, the association between ACOS and the incidence of CVDs has not been reported. This study investigated the relationship between CVDs and ACOS in the general population. SETTING: Data were obtained from Taiwan's National Health Insurance Research Database for the period 2000 to 2010. PARTICIPANTS: The ACOS cohort comprised patients (n=5814) who had received a diagnosis of asthma and COPD...
October 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28979308/sequential-and-mixed-genetic-algorithm-and-learning-automata-sgala-mgala-for-feature-selection-in-qsar
#9
Habib MotieGhader, Sajjad Gharaghani, Yosef Masoudi-Sobhanzadeh, Ali Masoudi-Nejad
Feature selection is of great importance in Quantitative Structure-Activity Relationship (QSAR) analysis. This problem has been solved using some meta-heuristic algorithms such as GA, PSO, ACO and so on. In this work two novel hybrid meta-heuristic algorithms i.e. Sequential GA and LA (SGALA) and Mixed GA and LA (MGALA), which are based on Genetic algorithm and learning automata for QSAR feature selection are proposed. SGALA algorithm uses advantages of Genetic algorithm and Learning Automata sequentially and the MGALA algorithm uses advantages of Genetic Algorithm and Learning Automata simultaneously...
2017: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/28979112/sputum-cell-count-biomarkers-in-the-differentiation-of-asthma-copd-and-asthma-copd-overlap
#10
Jie Gao, Wutie Zhou, Bida Chen, Weiming Lin, Sifang Wu, Feng Wu
INTRODUCTION: Cell count in induced sputum is a noninvasive biomarker to assess airway inflammation phenotypes. Accordingly, sputum cell counts are extensively used in the treatment of asthma and COPD. Nevertheless, the clinical application of sputum cell counts in patients with asthma-COPD overlap (ACO) remains elusive. The aim of this study was to investigate sputum cell counts in patients with ACO which are different from those in patients with asthma and COPD and also to examine the relationship between sputum cell counts in bronchial reversibility and bronchial hyperresponsiveness (BHR)...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28977242/the-essence-of-care-in-health-vulnerability-a-heideggerian-construction
#11
Virna Ribeiro Feitosa Cestari, Thereza Maria Magalhães Moreira, Vera Lúcia Mendes de Paula Pessoa, Raquel Sampaio Florêncio, Maria Rocineide Ferreira da Silva, Raimundo Augusto Martins Torres
Objective: Reflect on the essence of care in health vulnerability from the phenomenological perspective of Martin Heidegger. Method: Theoretical-reflexive study, anchored in three essential parts: 1) Care in Heidegger; 2) The essence of care in health vulnerability; And 3) Nursing care actions on health vulnerability. Results: Vulnerability must be recognized as an indelible trait of the human condition and has its constituents in the human being, co-presence and care...
September 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28977241/nursing-supervision-for-care-comprehensiveness
#12
Lucieli Dias Pedreschi Chaves, Vivian Aline Mininel, Jaqueline Alcântara Marcelino da Silva, Larissa Roberta Alves, Maria Ferreira da Silva, Silvia Helena Henriques Camelo
Objective: To reflect on nursing supervision as a management tool for care comprehensiveness by nurses, considering its potential and limits in the current scenario. Method: A reflective study based on discourse about nursing supervision, presenting theoretical and practical concepts and approaches. Results: Limits on the exercise of supervision are related to the organization of healthcare services based on the functional and clinical model of care, in addition to possible gaps in the nurse training process and work overload...
September 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28977231/knowledge-of-adolescents-regarding-sexually-transmitted-infections-and-pregnancy
#13
Rebeca Aranha Arrais Santos Almeida, Rita da Graça Carvalhal Frazão Corrêa, Isaura Letícia Tavares Palmeira Rolim, Jessica Marques da Hora, Andrea Gomes Linard, Nair Portela Silva Coutinho, Priscila da Silva Oliveira
Objective: To investigate the knowledge of adolescents related to sexually transmitted infections (STIs), AIDS, and pregnancy, and understand the role of school in sex education. Method: A qualitative descriptive study, developed through a semi-structured interview and a form for participant characterization, with 22 high school students from a public school aged 16 to 19 years. Data were submitted to content analysis. Results: After analysis, four thematic categories were developed: sexuality and sex education; understanding of risk behaviors; knowledge of STI/AIDS; and knowledge of and practices for prevention...
September 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28977226/prevention-of-chronic-complications-of-diabetes-mellitus-according-to-complexity
#14
Maria Aparecida Salci, Betina Hörner Schlindwein Meirelles, Denise Maria Vieira Guerreiro da Silva
Objective: To assess the prevention by primary health care providers of chronic complications of diabetes mellitus according to the complex thinking theoretical approach. Method: Evaluative research based on the complex thinking theoretical approach. The following techniques for data collection were used: interviews with 38 participants; observation in collective and individual appointments; and analysis of medical records of people with diabetes. The triangulation applied for data analysis was the ATLAS...
September 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28977222/weaving-the-west-psychosocial-care-network-of-the-municipality-of-s%C3%A3-o-paulo
#15
Maria do Perpétuo Socorro de Sousa Nóbrega, Alessandra Matheus Domingos, Ana Stella de Azevedo Silveira, Jussara Carvalho Dos Santos
Objective: to understand how health service professionals involved in the care of users in psychic distress perceive the organization of the Psychosocial Care Network (RAPS - Rede de Atenção Psicossocial) in the western region of the city of São Paulo. Method: qualitative approach study conducted with 123 professionals with higher education who work in the care points of the network. A semi-structured interview was performed and data were submitted to the Alceste program for lexical analysis...
September 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28977219/severity-and-workload-related-to-adverse-events-in-the-icu
#16
Clarita Terra Rodrigues Serafim, Magda Cristina Queiroz Dell'Acqua, Meire Cristina Novelli E Castro, Wilza Carla Spiri, Hélio Rubens de Carvalho Nunes
Objective: To analyze whether an increase in patient severity and nursing workload are correlated to a greater incidence of adverse events (AEs) in critical patients. Method: A prospective single cohort study was performed on a sample of 138 patients hospitalized in an intensive care unit (ICU). Results: A total of 166 AEs, occurred, affecting 50.7% of the patients. Increased patient severity presented a direct relationship to the probability of AEs occurring...
September 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28977216/experiences-in-the-family-health-strategy-demands-and-vulnerabilities-in-the-territory
#17
Antonio Germane Alves Pinto, Maria Salete Bessa Jorge, Mirna Neyara Alexandre de Sá Barreto Marinho, Emery Ciana Figueirêdo Vidal, Priscila de Souza Aquino, Eglídia Carla Figueirêdo Vidal
Objective: To understand the daily demands of Family Health Strategy in clinical practice of the team and social vulnerabilities of community territory. Method: Research with qualitative approach, in a critical-reflexive perspective, held with two teams of the Family Health Strategy, in the city of Fortaleza, State of Ceará, Brazil. The participants were 22 users and 19 health professionals from the basic health network. Data from the interviews and observation were analyzed under the assumptions of critical hermeneutics...
September 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28965921/therapeutic-approaches-of-asthma-and-copd-overlap
#18
REVIEW
Mitsuko Kondo, Jun Tamaoki
Asthma and COPD overlap (ACO) is an important clinical phenotype, due to the low-health-related quality of life (QOL), rapid decline in lung function, frequent exacerbation, and high economic burden. However, no large-scaled therapeutic trials of ACO have been conducted. At present, ACO is treated according to asthma/COPD guidelines. The goals of ACO treatment are to relieve symptoms and improve QOL and lung functions. Treatment must also prevent disease progression, airway remodeling, exacerbation, complications, and comorbidities...
September 28, 2017: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/28954166/care-coordination-in-pmaq-ab-an-item-response-theory-based-analysis
#19
Miriam Francisco de Souza, Alaneir de Fatima Dos Santos, Ilka Afonso Reis, Marcos Antônio da Cunha Santos, Alzira de Oliveira Jorge, Antônio Tomaz Gonzaga da Matta Machado, Eli Iola Gurgel Andrade, Mariangela Leal Cherchiglia
OBJECTIVE: Analyze the quality of the National Program for Primary Care Access and Quality Improvement variables to evaluate the coordination of primary care. METHODS: A cross-sectional study based on data from 17,202 primary care teams that participated in the National Program for Primary Care Access and Quality Improvement in 2012. Based on the Item Response Theory, Samejima's Gradual Response Model was used to estimate the score related to the level of coordination...
2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28954165/evaluation-of-the-performance-of-actions-and-outcomes-in-primary-health-care
#20
Paula Vitali Miclos, Maria Cristina Marino Calvo, Claudia Flemming Colussi
OBJECTIVE: The objective of this study has been to evaluate the performance of the primary care of Brazilian municipalities in relation to health actions and outcomes. METHODS: This is an evaluative, cross-sectional research, with a quantitative approach, aimed at the identification of the efficiency frontier of the primary care in health actions and outcomes in Brazilian municipalities. Secondary data have been collected from the Programa Nacional de Melhoria do Acesso e da Qualidade da Atenção Básica (National Program for Improving Access and Quality of Primary Care) and the Department of Informatics of the Brazilian Unified Health System, in 2012...
2017: Revista de Saúde Pública
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