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https://www.readbyqxmd.com/read/29457984/cardio-oncology-the-role-of-advanced-echocardiography-in-cancer-patients
#1
Lucia Venneri, Giacomo Zoppellaro, Rajdeep S Khattar
Cardio-oncology is a rapidly growing field aimed at improving the quality of care of cancer patients by preventing and monitoring cardiovascular complications resulting from cancer treatment. Cardiac imaging, and in particular, transthoracic echocardiography, plays an essential role in the baseline assessment and serial follow-up of cardio-oncology patients. Areas covered: This review article discusses the role of cardiac imaging with a focus on advanced echocardiography for the detection and management of cancer therapy related cardiovascular complications, in particular, left ventricular dysfunction and heart failure...
February 19, 2018: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/29457921/ribociclib-for-the-treatment-of-hormone-receptor-positive-human-epidermal-growth-factor-receptor-2-negative-advanced-breast-cancer
#2
Howard A Burris
The emergence of cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors marked a significant advancement in the treatment of advanced breast cancer. Ribociclib is an orally bioavailable, highly selective inhibitor of CDK4/6. In combination with various endocrine therapies, ribociclib has demonstrated clinical activity as a first-line therapy for patients with HR+, HER2- advanced breast cancer, without compromising the favorable toxicity profile associated with endocrine therapy. Thus, ribociclib is now considered a new standard of care for HR+, HER2- advanced breast cancer...
March 2018: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/29457753/bone-strength-and-exercise-during-youth-the-year-that-was-2017
#3
Kathleen F Janz, Fatima Baptista
The positive effects of physical activity on bone strength are certain. However, researchers have yet to precisely quantify the contribution of specific characteristics of physical activity that affect bone strength in children and adolescents. This commentary highlights 2 noteworthy 2017 publications that addressed osteogenic physical activity dose-response issues. Both papers moved the field forward by providing new insights on physical activity exposures beyond high-impact loading. Koedijk et al's paper was selected because, to the best of our knowledge, it is the first systematic review to solely examine associations between sedentary behavior and indicators of bone strength...
February 19, 2018: Pediatric Exercise Science
https://www.readbyqxmd.com/read/29457556/is-markedness-a-confused-concept
#4
Iris Berent
It is well known that, across languages, certain phonological features are more frequent than others. But whether these facts reflect abstract universal markedness constraints or functional pressures (auditory and articulatory difficulties and lexical frequency) is unknown. Romani, Galuzzi, Guariglia, and Goslin (2017) report that the putative markedness of phonological features captures their order of acquisition and their propensity to elicit errors in patients with an apraxia of speech (but not in phonological aphasia)...
October 2017: Cognitive Neuropsychology
https://www.readbyqxmd.com/read/29457553/the-difficulty-of-articulatory-complexity
#5
Marianne Pouplier, Stefania Marin, Alexei Kochetov
In our commentary, we offer some support for the view that frequency rather than a language-independent definition of complexity is a main factor determining speech production in healthy adults. We further discuss the limits of defining articulatory complexity based on transcription data. If we want to gauge the impact of substantive constraints on speech production, context-specific production dynamics should be considered, as has been underscored by articulatory-acoustic work on speech errors.
October 2017: Cognitive Neuropsychology
https://www.readbyqxmd.com/read/29457239/patient-care-to-public-health-to-synthetic-biology
#6
EDITORIAL
(no author information available yet)
The January-February 2018 issue of the Hastings Center Report includes pieces addressing patient care concerns that lie at the original core of bioethics and pieces that reflect the field's growing breadth. Among the pieces getting at the original core is an article by philosopher Daniel Brudney on the moral values underpinning surrogate decision-making. The article and the two commentaries that follow it contribute to the debate on the moral authority of surrogate decision-makers. Several items in the issue take up matters of public health and health policy...
January 2018: Hastings Center Report
https://www.readbyqxmd.com/read/29456622/does-the-oncology-community-have-a-rejection-bias-when-it-comes-to-repurposed-drugs
#7
EDITORIAL
Bishal Gyawali, Pan Pantziarka, Sergio Crispino, Gauthier Bouche
Among the various measures proposed to combat the challenge of financial toxicity in cancer care, an important strategy is the use of lower-priced drugs instead of expensive alternatives. However, the oncology community seems to either ignore or more readily reject cheaper drugs in cancer care compared to more expensive alternatives. In this commentary, we present three examples of lower-priced drugs rejected or ignored by the oncology community and contrast this with three expensive drugs where persistent optimism remained despite negative clinical trial results...
2018: Ecancermedicalscience
https://www.readbyqxmd.com/read/29456369/commentary
#8
Vikas Dhikav, Kuljeet Singh Anand
No abstract text is available yet for this article.
January 2018: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29455803/invited-commentary
#9
Farhood Farjah
No abstract text is available yet for this article.
March 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29455802/invited-commentary
#10
T Bruce Ferguson
No abstract text is available yet for this article.
March 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29455801/invited-commentary
#11
Nadia A Clarizia, Marc Ruel
No abstract text is available yet for this article.
March 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29455800/invited-commentary
#12
T Brett Reece
No abstract text is available yet for this article.
March 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29455614/ddr1-a-major-player-in-renal-diseases
#13
Aude Dorison, Christos Chantziantoniou
Discoidin Domain Receptor 1 (DDR1) belongs to a family of two non-integrin collagen receptors, DDR1 and DDR2, which display a tyrosine kinase activity. DDR1 has been widely studied in different kind of pathologies including chronic kidney diseases (CKD). The aims of this commentary are 1. to review the existing information about DDR1 expression in healthy and diseased kidney, 2. to comment the data highlighting DDR1 as a major actor in CKD, 3. to suggest areas of research which require further investigation to better characterize the signaling pathways regulating DDR1 role in CKD...
February 19, 2018: Cell Adhesion & Migration
https://www.readbyqxmd.com/read/29454574/editorial-commentary-use-of-cerebral-embolic-protection-devices-during-transcatheter-aortic-valve-replacement
#14
EDITORIAL
Hemang B Panchal, Timir K Paul
No abstract text is available yet for this article.
February 5, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29454437/invited-commentary
#15
Jose I Almeida
No abstract text is available yet for this article.
March 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29454436/invited-commentary
#16
Peter Neglen
No abstract text is available yet for this article.
March 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29454373/subclinical-hypothyroidism-in-children-is-it-always-subclinical
#17
R Gallizzi, C Crisafulli, T Aversa, G Salzano, F De Luca, M Valenzise, G Zirilli
Aim of this commentary is to report current knowledges on the main clinical and metabolic abnormalities which might be observed in children with longstanding and untreated subclinical hypothyroidism (SH) and to comment the most recent views about natural evolution of thyroid function in the cases with either idiopathic or Hashimoto's thyroiditis-related SH. On the basis of these preliminary remarks, the essential guidelines for an appropriate and tailored management of SH children are also proposed.
February 17, 2018: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29453697/the-sacral-autonomic-outflow-is-parasympathetic-langley-got-it-right
#18
REVIEW
John P Horn
A recent developmental study of gene expression by Espinosa-Medina, Brunet and colleagues sparked controversy by asserting a revised nomenclature for divisions of the autonomic motor system. Should we re-classify the sacral autonomic outflow as sympathetic, as now suggested, or does it rightly belong to the parasympathetic system, as defined by Langley nearly 100 years ago? Arguments for rejecting Espinosa-Medina, Brunet et al.'s scheme subsequently appeared in e-letters and brief reviews. A more recent commentary in this journal by Brunet and colleagues responded to these criticisms by labeling Langley's scheme as a historical myth perpetuated by ignorance...
February 16, 2018: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/29452405/commentary-neurosurgery-and-the-ongoing-american-opioid-crisis
#19
Kurt A Yaeger, Robert J Rothrock, Brian Harris Kopell
No abstract text is available yet for this article.
February 14, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29452337/commentary-on-oral-contraceptive-management-in-aesthetic-surgery-a-survey-of-current-practice-trends
#20
Nicholas L Berlin, Christopher J Pannucci, Edwin G Wilkins
No abstract text is available yet for this article.
February 14, 2018: Aesthetic Surgery Journal
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