keyword
MENU ▼
Read by QxMD icon Read
search

Parasite

keyword
https://www.readbyqxmd.com/read/29458070/the-epigenetic-alterations-of-endogenous-retroelements-in-aging
#1
REVIEW
Maurizio Cardelli
Endogenous retroelements, transposons that mobilize through RNA intermediates, include some of the most abundant repetitive sequences of the human genome, such as Alu and LINE-1 sequences, and human endogenous retroviruses. Recent discoveries demonstrate that these mobile genetic elements not only act as intragenomic parasites, but also exert regulatory roles in living cells. The risk of genomic instability represented by endogenous retroelements is normally counteracted by a series of epigenetic control mechanisms which include, among the most important, CpG DNA methylation...
February 16, 2018: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/29458008/trefoil-factor-2-promotes-type-2-immunity-and-lung-repair-through-intrinsic-roles-in-hematopoietic-and-non-hematopoietic-cells
#2
Li-Yin Hung, Taylor K Oniskey, Debasish Sen, Matthew F Krummel, Andrew E Vaughan, Noam A Cohen, De'Broski R Herbert
Trefoil factors are small secreted proteins that regulate tissue integrity and repair at mucosal surfaces, particularly in the gastrointestinal tract. However, their relative contribution(s) to controlling baseline lung function or the extent of infection-induced lung injury are unknown issues. Using irradiation bone marrow chimeras, we found that Trefoil factor 2 (TFF2) produced from both hematopoietic- and non-hematopoietic-derived cells is essential for host protection, proliferation of alveolar type 2 cells, and restoration of pulmonary gas exchange following infection with the hookworm parasite Nippostrongylus brasiliensis...
February 16, 2018: American Journal of Pathology
https://www.readbyqxmd.com/read/29457936/prevalence-structure-and-distribution-of-novel-parasite-cysts-containing-dracunculus-species-in-river-otters-lontra-canadensis-from-arkansas
#3
Renn Tumlison, Allison Surf
Adult female Guinea worms (Dracunculus spp.) usually are reported to occur singly in the extremities of their hosts, from which they deliver their larvae through fistulae in the host's skin into the water. We visually examined for presence of worms in the fascia of the limbs of skinned carcasses of 184 river otters (Lontra canadensis) harvested in Arkansas, and report observations of cysts on wrists and ankles found on 12 otters. Cysts averaged 15.6 X 24.6 mm in size, were round to oval, and contained masses of up to 19 adult female Dracunculus sp...
February 19, 2018: Journal of Parasitology
https://www.readbyqxmd.com/read/29457197/inactivation-of-the-indole-diterpene-biosynthetic-gene-cluster-of-claviceps-paspali-by-agrobacterium-mediated-gene-replacement
#4
László Kozák, Zoltán Szilágyi, Barbara Vágó, Annamária Kakuk, László Tóth, István Molnár, István Pócsi
The hypocrealean fungus Claviceps paspali is a parasite of wild grasses. This fungus is widely utilized in the pharmaceutical industry for the manufacture of ergot alkaloids, but also produces tremorgenic and neurotoxic indole-diterpene (IDT) secondary metabolites such as paspalitrems A and B. IDTs cause significant losses in agriculture and represent health hazards that threaten food security. Conversely, IDTs may also be utilized as lead compounds for pharmaceutical drug discovery. Current protoplast-mediated transformation protocols of C...
February 19, 2018: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29457150/the-links-between-agriculture-anopheles-mosquitoes-and-malaria-risk-in-children-younger-than-5-years-in-the-democratic-republic-of-the-congo-a-population-based-cross-sectional-spatial-study
#5
Mark M Janko, Seth R Irish, Brian J Reich, Marc Peterson, Stephanie M Doctor, Melchior Kashamuka Mwandagalirwa, Joris L Likwela, Antoinette K Tshefu, Steven R Meshnick, Michael E Emch
Background: The relationship between agriculture, Anopheles mosquitoes, and malaria in Africa is not fully understood, but it is important for malaria control as countries consider expanding agricultural projects to address population growth and food demand. Therefore, we aimed to assess the effect of agriculture on Anopheles biting behaviour and malaria risk in children in rural areas of the Democratic Republic of the Congo (DR Congo). Methods: We did a population-based, cross-sectional, spatial study of rural children (<5 years) in the DR Congo...
February 2018: Lancet. Planetary Health
https://www.readbyqxmd.com/read/29456967/editorial-parasite-infections-from-experimental-models-to-natural-systems
#6
EDITORIAL
Toni Aebischer, Kai Matuschewski, Susanne Hartmann
No abstract text is available yet for this article.
2018: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29456818/synthesis-and-antiplasmodial-activity-of-novel-phenanthroline-derivatives-an-in-vivo-study
#7
Azar Tahghighi, Safoura Karimi, Arezoo Rafie Parhizgar, Sedigheh Zakeri
Objectives: Due to the rapid increased drug resistance to Plasmodium parasites, an urgent need to achieve new antiplasmodial drugs is felt. Therefore, in this study, the new synthetic phenanthroline derivatives were synthesized with antiplasmodial activity. Materials and Methods: A series of 1,10-phenanthroline derivatives containing amino-alcohol and amino-ether substituents were synthesized via facile procedures, starting with 5,6-epoxy-1,10-phenanthroline. Their antiplasmodial activity was then evaluated using Peter's 4-day suppressive test against Plasmodium berghei-infected mice (ANKA strain)...
February 2018: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29456677/concurrent-eosinophilia-and-igg4-related-disease-in-a-child-a-case-report-and-review-of-the-literature
#8
Can Chen, Kuang Chen, Xilian Huang, Kaile Wang, Shenxian Qian
The current study presents the case of a 9-year-old Chinese boy who presented with eosinophilia and elevated serum levels of immunoglobulin G4 (IgG4). A bone marrow puncture identified an elevated eosinophil rate of 23% (normal range, <5%), which indicated eosinophilia. However, gene analysis, fluorescent in situ hybridization and other examinations, including bone marrow aspiration, blood routine, auto-antibody tests and parasitic and allergens screening, contradicted a diagnosis of secondary or clonal eosinophilia...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29456374/factors-affecting-primaquine-combination-treatment-in-malaria-patients-in-selangor-malaysia
#9
Norliza Mat Ariffin, Farida Islahudin, Mohd Makmor-Bakry, Endang Kumolosasi, Mohd Hafizi A Hamid
Introduction: Primaquine is vital for the management of liver-stage Plasmodium vivax and Plasmodium ovale malaria. However, primaquine effectiveness is dependent on various factors and differs between populations. Therefore, this study was conducted to identify factors that affect the length of stay and relapse during primaquine combination treatment in malaria-infected patients in the local setting. Materials and Methods: A retrospective study on the use of primaquine combination among P...
October 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29456188/parasitism-and-the-biodiversity-functioning-relationship
#10
REVIEW
André Frainer, Brendan G McKie, Per-Arne Amundsen, Rune Knudsen, Kevin D Lafferty
Species interactions can influence ecosystem functioning by enhancing or suppressing the activities of species that drive ecosystem processes, or by causing changes in biodiversity. However, one important class of species interactions - parasitism - has been little considered in biodiversity and ecosystem functioning (BD-EF) research. Parasites might increase or decrease ecosystem processes by reducing host abundance. Parasites could also increase trait diversity by suppressing dominant species or by increasing within-host trait diversity...
February 15, 2018: Trends in Ecology & Evolution
https://www.readbyqxmd.com/read/29455921/clinical-and-epidemiological-characteristics-of-intestinal-parasite-infection-by-blastocystis-hominis
#11
C Ocaña-Losada, J A Cuenca-Gómez, M T Cabezas-Fernández, J Vázquez-Villegas, M J Soriano-Pérez, I Cabeza-Barrera, J Salas-Coronas
OBJECTIVES: Blastocystis hominis (B. hominis) is one of the most common intestinal parasites isolated in humans. The parasite can cause gastrointestinal symptoms or, in most cases, remain asymptomatic. There are issues concerning the parasite's pathogenic character. The aim of this study was to analyse the clinical and epidemiological characteristics of the parasite infection by B. hominis, with or without other parasitic co-infections. PATIENTS AND METHODS: An observational retrospective study was conducted of B...
February 15, 2018: Revista Clínica Española
https://www.readbyqxmd.com/read/29455691/a-new-species-of-parapharyngodon-chatterji-1933-oxyuroidea-pharyngodonidae-parasitic-in-osteocephalus-taurinus-anura-hylidae-from-brazil
#12
T A P Santos, E G G Argolo, A N Santos, A R O Rodrigues, C E Gonzaléz, J N Santos, F T V Melo
Parapharyngodon politoedi n. sp. is described here, based on specimens found in the large intestines of Osteocephalus taurinus from the Caxiuanã National Forest, State of Pará, Brazil. The new species is assigned to Parapharyngodon based on the presence of non-embryonated eggs with sub-terminal opercula, when in the ovijector. Parapharyngodon politoedi belongs to a group of species with three pairs of cloacal papillae and differs from its congeners by morphometric aspects, such as the length of the spicule, and the combination of the following morphological characters: ovaries never encircling the oesophagus, tail shape in females, cloacal lips, sharply pointed spicule and presence of genital cone...
February 19, 2018: Journal of Helminthology
https://www.readbyqxmd.com/read/29455678/cryptic-species-and-their-utilization-of-indigenous-and-non-indigenous-intermediate-hosts-in-the-acanthocephalan-polymorphus-minutus-sensu-lato-polymorphidae
#13
Maike Zittel, Daniel Grabner, Andre Wlecklik, Bernd Sures, Florian Leese, Horst Taraschewski, Alexander Martin Weigand
The bird-infecting acanthocephalan Polymorphus minutus has been suggested to comprise different lineages or even cryptic species using different intermediate hosts. To clarify this open question, we investigated Polymorphus cf. minutus cystacanths originating from amphipod intermediate hosts from 27 sites in Germany and France. Parasites and hosts were identified using integrated datasets (COI and/or morphology for hosts and COI + ITS1-5.8S-ITS2 for parasites). Mitochondrial and nuclear data (ITS1) strongly support the existence of three cryptic species in Polymorphus cf...
February 19, 2018: Parasitology
https://www.readbyqxmd.com/read/29455427/variation-in-cardiac-markers-and-electrocardiographic-alterations-in-young-calves-naturally-infected-with-bovine-tropical-theileriosis
#14
Kapil Kumar Gupta, Mukesh Srivastava, Vikrant Sudan, Shanker Kumar Singh, Soumen Choudhury, Daya Shanker
The present study was designed to assess the deleterious effects of bovine tropical theileriosis on the cardiovascular system and the consequent myocardial involvement in young calves. Myocardial effects in parasitic diseases are often neglected. Hemolytic anemia, associated secondary hypoxia, and vasculitis are cardinal features of bovine theileriosis. In the present study, electrocardiogram (ECG) alongside serum cardiac troponin I (cTnI) and creatinine phosphokinase-myocardial band (CPK-MB) concentrations were analyzed in infected, treated, and control groups of young calves...
February 17, 2018: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29455420/molecular-characterization-of-hepatozoon-canis-from-farm-dogs-in-pakistan
#15
Abdullah S Ahmad, Muhammad A Saeed, Imran Rashid, Kamran Ashraf, Wasim Shehzad, Rebecca J Traub, Gad Baneth, Abdul Jabbar
Hepatozoon canis is a tick-borne pathogen of canids, which is distributed worldwide. However, very little is known about this protozoan parasite in Pakistan. This study provides the first molecular evidence of H. canis from farm dogs from three agro-ecological zones of Punjab, Pakistan. A conventional PCR targeting the 18S rRNA gene was used to characterize H. canis from farm dogs from three districts, namely Kasur, Rawalpindi, and Muzaffargarh, in Punjab. Of 341 blood samples tested, 155 (45.5%) were positive for H...
February 18, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29455419/further-aspects-of-toxoplasma-gondii-elimination-in-the-presence-of-metals
#16
Laís Pessanha de Carvalho, Edésio José Tenório de Melo
Toxoplasma gondii, the etiological agent of toxoplasmosis, infects nucleated cells and then resides and multiplies within a parasitophorous vacuole. For this purpose, the parasite secretes many virulence factors for the purpose of invading and subverting the host microbicidal defenses in order to facilitate its survival in the intracellular milieu. Essential metals are structural components of proteins and enzymes or cofactors of enzymatic reactions responsible for these parasitic survival mechanisms. However, an excess of non-essential or essential metals can lead to parasite death...
February 18, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29455088/parasite-susceptibility-in-an-amphibian-host-is-modified-by-salinization-and-predators
#17
Nicholas Buss, Jessica Hua
Secondary salinization represents a global threat to freshwater ecosystems. Salts, such as NaCl, can be toxic to freshwater organisms and may also modify the outcome of species interactions (e.g. host-parasite interactions). In nature, hosts and their parasites are embedded in complex communities where they face anthropogenic and biotic (i.e. predators) stressors that influence host-parasite interactions. As human populations grow, considering how anthropogenic and natural stressors interact to shape host-parasite interactions will become increasingly important...
February 15, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29454982/improved-genomic-resources-and-new-bioinformatic-workflow-for-the-carcinogenic-parasite-clonorchis-sinensis-biotechnological-implications
#18
REVIEW
Daxi Wang, Pasi K Korhonen, Robin B Gasser, Neil D Young
Clonorchis sinensis (family Opisthorchiidae) is an important foodborne parasite that has a major socioeconomic impact on ~35 million people predominantly in China, Vietnam, Korea and the Russian Far East. In humans, infection with C. sinensis causes clonorchiasis, a complex hepatobiliary disease that can induce cholangiocarcinoma (CCA), a malignant cancer of the bile ducts. Central to understanding the epidemiology of this disease is knowledge of genetic variation within and among populations of this parasite...
February 15, 2018: Biotechnology Advances
https://www.readbyqxmd.com/read/29454879/application-of-genetically-encoded-redox-biosensors-to-measure-dynamic-changes-in-the-glutathione-bacillithiol-and-mycothiol-redox-potentials-in-pathogenic-bacteria
#19
REVIEW
Quach Ngoc Tung, Nico Linzner, Vu Van Loi, Haike Antelmann
Gram-negative bacteria utilize glutathione (GSH) as their major LMW thiol. However, most Gram-positive bacteria do not encode enzymes for GSH biosynthesis and produce instead alternative LMW thiols, such as bacillithiol (BSH) and mycothiol (MSH). BSH is utilized by Firmicutes and MSH is the major LMW thiol of Actinomycetes. LMW thiols are required to maintain the reduced state of the cytoplasm, but are also involved in virulence mechanisms in human pathogens, such as Staphylococcus aureus, Mycobacterium tuberculosis, Streptococcus pneumoniae, Salmonella enterica subsp...
February 15, 2018: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29454845/evaluation-of-a-new-multiplex-pcr-assay-paragenie-g-amoeba-real-time-pcr-kit-targeting-giardia-intestinalis-entamoeba-histolytica-and-entamoeba-dispar-entamoeba-moshkovskii-from-stool-specimens-evidence-for-the-limited-performances-of-microscopy-based-approach
#20
Florent Morio, Stéphane Valot, Adrien Laude, Guillaume Desoubeaux, Nicolas Argy, Céline Nourrisson, Christelle Pomares, Marie Machouart, Yohann Le Govic, Frédéric Dalle, Françoise Botterel, Nathalie Bourgeois, Estelle Cateau, Marion Leterrier, Fakhri Jeddi, Manuel Gaboyard, Patrice Le Pape
OBJECTIVES: Besides the potential to identify a wide variety of gastrointestinal parasites, microscopy remains the gold standard in clinical microbiology for amoeba species identification and especially, when coupled with adhesin detection, to discriminate the pathogenic E. histolytica from its sisters but non-pathogenic species E. dispar/E. moschovskii. However, this approach is time-consuming, requires a high-level of expertise that can be jeopardized considering the low prevalence of gastrointestinal parasites in non-endemic countries...
February 15, 2018: Clinical Microbiology and Infection
keyword
keyword
26614
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"