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https://www.readbyqxmd.com/read/28919796/psoriasis-and-vitiligo-are-close-relatives
#1
Khalifa E Sharquie, Husam Ali Salman, Aseel K Yaseen
BACKGROUND: Both vitiligo and psoriasis are chronic inflammatory autoimmune diseases with genetic elements. OBJECTIVE: To estimate the frequencies of psoriasis in vitiligo patients and vice versa and to compare them with healthy controls. PATIENTS AND METHODS: A total of 1000 subjects were included, 250 of them had vitiligo, 250 had psoriasis, and 500 were healthy controls. Measurement of the frequencies of vitiligo in psoriatic patients and psoriasis in vitiligo patients was carried out...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/28915177/bad-response-or-bad-luck-a-new-versus-recrudescent-sepsis-readmission
#2
Ramzy Husam Rimawi
No abstract text is available yet for this article.
October 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28913395/simultaneous-bilateral-total-hip-arthroplasty-in-morquio-syndrome
#3
Imran Ilyas, Syed Kashif, Samar Rabbani, Husam A Alrumaih
A 16-year-old girl who had Morquio syndrome presented with severe bilateral hip pain and limited mobility because of bilateral hip osteoarthritis and fixed flexion deformities. She was wheelchair bound for the previous 6 months. Cervical spine flexion-extension views showed mild subluxation (<3 mm), and there was thoracolumbar spine kyphosis. Magnetic resonance imaging of the cervical and thoracolumbar spine showed hypoplasia of the odontoid and vertebral bodies, but no spinal cord compression. Bilateral cemented total hip arthroplasty was performed through a posterior approach under general anesthesia with fiberoptic intubation...
September 2017: Arthroplasty Today
https://www.readbyqxmd.com/read/28890819/the-role-of-induction-chemotherapy-chemoradiotherapy-in-localised-pancreatic-cancer-initial-experience-in-scotland
#4
Derek Grose, David McIntosh, Nigel Jamieson, Ross Carter, Euan Dickson, David Chang, Husam Marashi, Christina Wilson, Mohammed Alfayez, Ashleigh Kerr, Roisin O'Donoghue, Lea Haskins, Fraser Duthie, Colin J McKay, Janet Graham
BACKGROUND: Despite being relatively rare pancreatic cancer is one of the highest causes of death. Even within the potentially resectable group outcomes are poor. We present our initial experiences utilising a neoadjuvant approach to localised pancreatic cancer, evaluating survival, response rates and tolerability. METHODS: This was a retrospective analysis of a prospectively maintained database. Patients from 2012 to 2015 referred to a busy regional Hepato-Pancreatic Biliary (HPB) MDT were included...
August 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28871820/acute-heart-failure-presentations-and-outcomes-during-the-fasting-month-of-ramadan-an-observational-report-from-seven-middle-eastern-countries
#5
Amar M Salam, Kadhim Sulaiman, Alawi A Alsheikh-Ali, Rajvir Singh, Nidal Asaad, Awad Al-Qahtani, Imtiaz Salim, Khalid F AlHabib, Ibrahim Al-Zakwani, Mohammed Al-Jarallah, Wael AlMahmeed, Bassam Bulbanat, Mustafa Ridha, Nooshin Bazargani, Haitham Amin, Ahmed Al-Motarreb, Husam AlFaleh, Hanan Albackr, Prashanth Panduranga, Abdulla Shehab, Jassim Al Suwaidi
BACKGROUND: Fasting during the month of Ramadan is practiced by over one and a half billion Muslims worldwide. It remains unclear, however, how this change in lifestyle affects heart failure, a condition that has reached epidemic dimensions. We examined the effects of fasting in patients with acute heart failure (AHF) using data from a large multi-center heart failure registry. METHODS AND RESULTS: Data were derived from Gulf CARE (Gulf aCute heArt failuRe rEgistry), a prospective multicenter study of consecutive patients hospitalized with AHF during February-November 2012...
September 5, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28867551/stable-positioning-of-unc13-restricts-synaptic-vesicle-fusion-to-defined-release-sites-to-promote-synchronous-neurotransmission
#6
Suneel Reddy-Alla, Mathias A Böhme, Eric Reynolds, Christina Beis, Andreas T Grasskamp, Malou M Mampell, Marta Maglione, Meida Jusyte, Ulises Rey, Husam Babikir, Anthony W McCarthy, Christine Quentin, Tanja Matkovic, Dominique Dufour Bergeron, Zeeshan Mushtaq, Fabian Göttfert, David Owald, Thorsten Mielke, Stefan W Hell, Stephan J Sigrist, Alexander M Walter
Neural information processing depends on precisely timed, Ca(2+)-activated synaptic vesicle exocytosis from release sites within active zones (AZs), but molecular details are unknown. Here, we identify that the (M)Unc13-family member Unc13A generates release sites and show the physiological relevance of their restrictive AZ targeting. Super-resolution and intravital imaging of Drosophila neuromuscular junctions revealed that (unlike the other release factors Unc18 and Syntaxin-1A) Unc13A was stably and precisely positioned at AZs...
September 13, 2017: Neuron
https://www.readbyqxmd.com/read/28844937/dimercapto-1-propanesulfonic-acid-dmps-induces-metaphase-ii-mouse-oocyte-deterioration
#7
Sarah R Aldhaheri, Roohi Jeelani, Hamid-Reza Kohan-Ghadr, Sana N Khan, Sasha Mikhael, Christina Washington, Robert T Morris, Husam M Abu-Soud
In light of the recent lead contamination of the water in Flint, Michigan and its potential adverse outcomes, much research and media attention has turned towards the safety profile of commonly used chelators. Dimercapto-1-propanesulfonic acid (DMPS) typically used in the treatment of lead, mercury and arsenic poisoning also displays a high affinity towards transition metals such as zinc and copper, essential for biological functioning. It is given in series of dosages (0.2-0.4g/day) over a long period, and has the ability to enter cells...
August 24, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28828473/informed-consent-to-study-purpose-in-randomized-clinical-trials-of-antibiotics-1991-through-2011
#8
Peter Doshi, Peter Hur, Mark Jones, Husam Albarmawi, Tom Jefferson, Daniel J Morgan, Patricia A Spears, John H Powers
Importance: Potential research participants may assume that randomized trials comparing new interventions with older interventions always hypothesize greater efficacy for the new intervention, as in superiority trials. However, antibiotic trials frequently use "noninferiority" hypotheses allowing a degree of inferior efficacy deemed "clinically acceptable" compared with an older effective drug, in exchange for nonefficacy benefits (eg, decreased adverse effects). Considering these different benefit-harm trade-offs, proper informed consent necessitates supplying different information on the purposes of superiority and noninferiority trials...
August 21, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28794125/unexplained-abnormal-liver-function-in-patients-with-primary-antibody-deficiency-could-it-be-chronic-hepatitis-e-infection
#9
Omar E Mohamed, Julie Jones, Husam Osman, Aarnoud P Huissoon
Data from recent studies suggest rising incidence rate of hepatitis E virus (HEV) infection in the UK. HEV infection may take a severe and persistent course in immunocompromised patients, including transplant recipients on immunosuppressives, patients with HIV, haematological malignancies and in idiopathic CD4(+) T lymphocytopenia. The prevalence of HEV in primary antibody deficiency (PAD) disorders is still unknown. The aim of this study was to investigate HEV infection in 27 patients with PAD with unexplained, persistently elevated liver enzymes...
August 9, 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28765711/characteristics-and-predictors-of-progression-in-an-egyptian-multiple-sclerosis-cohort-a-multicenter-registry-study
#10
Sherif M Hamdy, Maged Abdel-Naseer, Nevin M Shalaby, Alaa N Elmazny, Ahmed A Nemr, Amr Hassan, Mohamed I Hegazy, Husam S Mourad, Nirmeen A Kishk, Mona A Nada, Ahmed Abdelalim, Amr M Fouad, Hatem S Shehata
BACKGROUND: Multiple sclerosis (MS) is a complex autoimmune disease with a heterogeneous presentation and diverse disease course. Recent studies indicate a rising prevalence of MS in the Middle East. OBJECTIVE: To characterize the demographics and disease features of Egyptian patients attending four tertiary referral MS centers in Cairo. MATERIALS AND METHODS: This was a retrospective, observational study on 1,581 patients between 2001 and 2015...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28763048/outdoor-performance-analysis-of-a-photovoltaic-thermal-pvt-collector-with-jet-impingement-and-compound-parabolic-concentrator-cpc
#11
Ahed Hameed Jaaz, Husam Abdulrasool Hasan, Kamaruzzaman Sopian, Abdul Amir H Kadhum, Tayser Sumer Gaaz, Ahmed A Al-Amiery
This paper discusses the effect of jet impingement of water on a photovoltaic thermal (PVT) collector and compound parabolic concentrators (CPC) on electrical efficiency, thermal efficiency and power production of a PVT system. A prototype of a PVT solar water collector installed with a jet impingement and CPC has been designed, fabricated and experimentally investigated. The efficiency of the system can be improved by using jet impingement of water to decrease the temperature of the solar cells. The electrical efficiency and power output are directly correlated with the mass flow rate...
August 1, 2017: Materials
https://www.readbyqxmd.com/read/28747217/persistence-of-candida-dubliniensis-and-lung-function-in-patients-with-cystic-fibrosis
#12
Atqah AbdulWahab, Husam Salah, Prem Chandra, Saad J Taj-Aldeen
OBJECTIVES: Candida dubliniensis is an emerging yeast and demonstrated a high adherence property to cystic fibrosis respiratory tract. Therefore, it is important to determine the persistence of C. dubliniensis and to assess the possible relationship to the body mass index (BMI) and forced expiratory volume in 1st second (FEV1). RESULTS: Candida isolates were identified by MALDI-TOF MS to species level from 40/52 (76.9%) cystic fibrosis patients. C. dubliniensis was the most common organism isolated from 50/77 (65%) lower respiratory specimens of 29 patients...
July 26, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28734829/feasibility-of-prophylactic-salpingectomy-during-vaginal%C3%A2-hysterectomy
#13
Danielle D Antosh, Rachel High, Heidi W Brown, Sallie S Oliphant, Husam Abed, Nisha Philip, Cara L Grimes
BACKGROUND: The American Congress of Obstetricians and Gynecologists recommends that "the surgeon and patient discuss the potential benefits of the removal of the fallopian tubes during a hysterectomy in women at population risk of ovarian cancer who are not having an oophorectomy," resulting in an increasing rate of salpingectomy at the time of hysterectomy. Rates of salpingectomy are highest for laparoscopic and lowest for vaginal hysterectomy. OBJECTIVE: The primary objective of this study was to determine the feasibility of bilateral salpingectomy at the time of vaginal hysterectomy...
July 20, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28723173/laser-scribed-graphene-electrodes-for-aptamer-based-biosensing
#14
Christoph Fenzl, Pranati Nayak, Thomas Hirsch, Otto S Wolfbeis, Husam N Alshareef, Antje J Baeumner
Graphene as a transducer material has produced some of the best-performing sensing approaches to date opening the door toward integrated miniaturized all-carbon point-of-care devices. Addressing this opportunity, laser-scribed graphene (LSG) electrodes are demonstrated here as highly sensitive and reliable biosensor transducers in blood serum analysis. These flexible electrodes with large electrochemical surface areas were fabricated using a direct-write laser process on polyimide foils. A universal immobilization approach is established by anchoring 1-pyrenebutyric acid to the graphene and subsequently covalently attaching an aptamer against the coagulation factor thrombin as an exemplary bioreceptor to the carboxyl groups...
May 26, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28720108/early-pregnancy-sex-steroids-during-primiparous-pregnancies-and-maternal-breast-cancer-a-nested-case-control-study-in-the-northern-sweden-maternity-cohort
#15
Renée T Fortner, Eglé Tolockiene, Helena Schock, Husam Oda, Hans-Åke Lakso, Göran Hallmans, Rudolf Kaaks, Paolo Toniolo, Anne Zeleniuch-Jacquotte, Kjell Grankvist, Eva Lundin
BACKGROUND: Pregnancy and parity are associated with subsequent breast cancer risk. Experimental and epidemiologic data suggest a role for pregnancy sex steroid hormones. METHODS: We conducted a nested case-control study in the Northern Sweden Maternity Cohort (1975-2007). Eligible women had provided a blood sample in the first 20 weeks of gestation during a primiparous pregnancy leading to a term delivery. The current study includes 223 cases and 417 matched controls (matching factors: age at and date of blood collection)...
July 18, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28711708/ezetimibe-and-simvastatin-combination-inhibits-and-reverses-the-pro-inflammatory-and-pro-atherogenic-effects-of-cream-in-obese-patients
#16
Husam Ghanim, Kelly Green, Sanaa Abuaysheh, Reema Patel, Manav Batra, Ajay Chaudhuri, Antoine Makdissi, Nitesh D Kuhadiya, Paresh Dandona
BACKGROUND AND AIMS: Inflammation and postprandial lipemia are associated with increased cardiovascular disease. We investigated whether ezetimibe and simvastatin combination, a lipid lowering combination of simvastatin and ezetimibe, exerts an anti-inflammatory effect in the fasting state and after dairy cream intake. METHODS: Twenty obese patients were randomized to either ezetimibe and simvastatin combination or placebo treatment for 6 weeks. All patients were asked to ingest 33 ml of dairy cream (300 Calories) at the beginning and at the end of intervention...
June 7, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28708680/distinguishing-pneumonia-from-pneumonitis-to-safely-discontinue-antibiotics
#17
Ramzy Husam Rimawi
No abstract text is available yet for this article.
August 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28705122/the-effect-of-using-mobile-applications-for-improving-oral-hygiene-in-patients-with-orthodontic-fixed-appliances-a-randomised-controlled-trial
#18
Omar H Alkadhi, Mohammed N Zahid, Read S Almanea, Husam K Althaqeb, Turki H Alharbi, Nancy M Ajwa
OBJECTIVE: To investigate the effect of using mobile applications active reminders to improve oral hygiene in comparison to verbal oral hygiene instructions. DESIGN: Two-arm parallel randomised controlled trial. SETTING: orthodontic clinics at two branches of a university hospitals of the college of dentistry of Riyadh Colleges of Dentistry and Pharmacy, Riyadh, Saudi Arabia. PARTICIPANTS: Forty-four 12-year-old and older subjects...
July 13, 2017: Journal of Orthodontics
https://www.readbyqxmd.com/read/28694343/non-withdrawal-of-beta-blockers-in-acute-decompensated-chronic-and-de-novo-heart-failure-with-reduced-ejection-fraction-in-a-prospective-multicentre-study-of-patients-with-acute-heart-failure-in-the-middle-east
#19
Charbel Abi Khalil, Kadhim Sulaiman, Ziyad Mahfoud, Rajvir Singh, Nidal Asaad, Khalid F AlHabib, Alawi Alsheikh-Ali, Mohammed Al-Jarallah, Bassam Bulbanat, Wael AlMahmeed, Mustafa Ridha, Nooshin Bazargani, Haitham Amin, Ahmed Al-Motarreb, Husam Al Faleh, Abdelfatah Elasfar, Prashanth Panduranga, Jassim Al Suwaidi
OBJECTIVES: Beta blockers reduce mortality in heart failure (HF). However, it is not clear whether they should be temporarily withdrawn during acute HF. DESIGN: Analysis of prospectively collected data. SETTING: The Gulf aCute heArt failuRe rEgistry is a prospective multicentre study of patients hospitalised with acute HF in seven Middle Eastern countries. PARTICIPANTS: 5005 patients with acute HF. OUTCOME MEASURES: We studied the effect of beta blockers non-withdrawal on intrahospital, 3-month and 12-month mortality and rehospitalisation for HF in patients with acute decompensated chronic heart failure (ADCHF) and acute de novo heart failure (ADNHF) and a left ventricular ejection fraction (LVEF) <40%...
July 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28690871/cervical-spine-epidural-abscess-a-single-center-analytical-comparison-to-the-literature
#20
Faris Shweikeh, Mohammed Hussain, Ajleeta Sangtani, Husam Issa, Asif Bashir, J Patrick Johnson, Georges Z Markarian
STUDY DESIGN: Retrospective review of patient charts. OBJECTIVES: Cervical spine epidural abscess (CSEA) is uncommon. In this study, characteristics of CSEA patients are described through an institutional analysis and literature review. SETTING: University-affiliated city hospital. METHODS: The electronic medical record was searched from 01/2001 to 01/2012. Data on presentation, comorbidities, diagnostic modalities, pathogens, treatments, and neurological recovery were collected...
2017: Spinal Cord Series and Cases
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