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High fructose corn syrup

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https://www.readbyqxmd.com/read/29757229/effect-of-dietary-sugar-intake-on-biomarkers-of-subclinical-inflammation-a-systematic-review-and-meta-analysis-of-intervention-studies
#1
REVIEW
Karen W Della Corte, Ines Perrar, Katharina J Penczynski, Lukas Schwingshackl, Christian Herder, Anette E Buyken
It has been postulated that dietary sugar consumption contributes to increased inflammatory processes in humans, and that this may be specific to fructose (alone, in sucrose or in high-fructose corn syrup (HFCS)). Therefore, we conducted a meta-analysis and systematic literature review to evaluate the relevance of fructose, sucrose, HFCS, and glucose consumption for systemic levels of biomarkers of subclinical inflammation. MEDLINE, EMBASE, and Cochrane libraries were searched for controlled intervention studies that report the effects of dietary sugar intake on (hs)CRP, IL-6, IL-18, IL-1RA, TNF-α, MCP-1, sICAM-1, sE-selectin, or adiponectin...
May 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29627319/whole-cell-immobilization-of-refractory-glucose-isomerase-using-tris-hydroxymethyl-phosphine-as-crosslinker-for-preparation-of-high-fructose-corn-syrup-at-elevated-temperature
#2
Dong-Xu Jia, Teng Wang, Zi-Jian Liu, Li-Qun Jin, Jia-Jia Li, Cheng-Jun Liao, De-Shui Chen, Yu-Guo Zheng
Glucose isomerase (GI) responsible for catalyzing the isomerization from d-glucose to d-fructose, was an important enzyme for producing high fructose corn syrup (HFCS). In a quest to prepare HFCS at elevated temperature and facilitate enzymatic recovery, an effective procedure for whole cell immobilization of refractory Thermus oshimai glucose isomerase (ToGI) onto Celite 545 using tris(hydroxymethyl)phosphine (THP) as crosslinker was established. The immobilized biocatalyst showed an activity of approximate 127...
April 4, 2018: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/29618406/direct-comparison-of-cavity-ring-down-spectrometry-and-isotope-ratio-mass-spectrometry-for-detection-of-sugar-adulteration-in-honey-samples
#3
Madhavi Mantha, John R Urban, William A Mark, Anatoly Chernyshev, Kevin M Kubachka
In the last several years, economically motivated adulteration (EMA) of foods including honey has received increased attention. The addition of inexpensive sweeteners such as high fructose corn syrup or cane sugar to honey is still encountered despite scientific methods that can routinely detect this type of adulteration. The standard method for detection of these adulterants utilizes isotope ratio mass spectrometry (IRMS); however, this technique requires an elevated degree of technical knowledge for operation as well as a high cost for purchase and maintenance...
April 4, 2018: Journal of AOAC International
https://www.readbyqxmd.com/read/29587887/excess-free-fructose-high-fructose-corn-syrup-and-adult-asthma-the-framingham-offspring-cohort
#4
Luanne R DeChristopher, Katherine L Tucker
There is growing evidence that intakes of high-fructose corn syrup (HFCS), HFCS-sweetened soda, fruit drinks and apple juice - a high-fructose 100 % juice - are associated with asthma, possibly because of the high fructose:glucose ratios and underlying fructose malabsorption, which may contribute to enteral formation of pro-inflammatory advanced glycation end products, which bind receptors that are mediators of asthma. Cox proportional hazards models were used to assess associations between intakes of these beverages and asthma risk, with data from the Framingham Offspring Cohort...
March 28, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29534480/characterization-of-the-types-of-sweeteners-consumed-in-honduras
#5
Adriana Hernández, Adriana Beatriz Di Iorio, Jeffrey Lansdale, María Belén Salazar
Sweeteners are found in all types of foods, and their high consumption is associated with chronic degenerative diseases, such as diabetes and obesity, among others. A characterization was carried out of food products with sweeteners from the three biggest supermarkets at a national level; they were identified by the list of ingredients and classified according to caloric or non-caloric intake, and pursuant to their country of origin. A statistical interpretation of results was made using descriptive measures such as the number of times the sweeteners were found in the formulation of the products and how many of them were found in a product at the same time...
March 11, 2018: Nutrients
https://www.readbyqxmd.com/read/29521600/cecal-versus-fecal-microbiota-in-ossabaw-swine-and-implications-for-obesity
#6
Matthew R Panasevich, Umesh D Wankhade, Sree V Chintapalli, Kartik Shankar, R Scott Rector
The gut microbiome plays a critical role in the onset and progression of obesity and the metabolic syndrome. However, it is not well documented whether the cecal vs. the fecal microbiome is more relevant when assessing their contributions to these diseases. Here, we amplified the V4 region of the 16S rRNA gene from cecal and fecal samples of female Ossabaw swine fed a low-fat control diet (10.5% fat, n = 4) or Western diet (43.0% fat, 17.8% high fructose corn syrup, 2% cholesterol; n = 3) for 36 wk. Obesity significantly lowered alpha-diversity ( P < 0...
May 1, 2018: Physiological Genomics
https://www.readbyqxmd.com/read/29514881/fructose-containing-caloric-sweeteners-as-a-cause-of-obesity-and-metabolic-disorders
#7
REVIEW
Luc Tappy
Compared with other carbohydrates, fructose-containing caloric sweeteners (sucrose, high-fructose corn syrup, pure fructose and fructose-glucose mixtures) are characterized by: a sweet taste generally associated with a positive hedonic tone; specific intestinal fructose transporters, i.e. GLUT5; a two-step fructose metabolism, consisting of the conversion of fructose carbones into ubiquitous energy substrates in splanchnic organs where fructolytic enzymes are expressed, and secondary delivery of these substrates to extrasplanchnic tissues...
March 7, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29429321/expression-and-characterization-of-calcium-and-zinc-tolerant-xylose-isomerase-from-anoxybacillus-kamchatkensis-g10
#8
Yeong-Jun Park, Byung Kwon Jung, Sung-Jun Hong, Gun-Seok Park, Jerald Conrad Ibal, HuyQuang Pham, Jae-Ho Shin
The enzyme xylose isomerase (EC 5.3.1.5, XI) is responsible for theconversion of an aldose to ketose, especially xylose to xylulose. Owing to the ability of XI to isomerize glucose to fructose, this enzyme is used in the food industry to prepare high-fructose corn syrup. Therefore, we studiedthe characteristics of XI from Anoxybacillus kamchatkensis G10, a thermophilic bacterium. First, a gene coding for XI ( xylA ) was insertedinto the pET-21a (+) expression vector and the construct was transformed into an Escherichia coli competent cell BL21 (DE3)...
February 13, 2018: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29423591/inhibitory-effect-of-bofutsushosan-fang-feng-tong-sheng-san-on-glucose-transporter-5-function-in-vitro
#9
Shengli Gao, Hideo Satsu, Toshiaki Makino
Bofutsushosan (BTS; fang feng tong sheng san in Chinese) is a formula in traditional Japanese Kampo medicine and Chinese medicine comprising eighteen crude drugs, and is used to treat obesity and metabolic syndrome. Fructose is contained in refreshing beverages as high-fructose corn syrup, and is associated with obesity. Fructose is absorbed via glucose transporter 5 (GLUT5) in the intestine. Therefore, the inhibition of GLUT5 is considered to be a target of obesity drugs. We evaluated the inhibitory effects of BTS extract and its constituents on fructose uptake using Chinese hamster ovary K1 cells, i...
March 2018: Journal of Natural Medicines
https://www.readbyqxmd.com/read/29408694/fructose-and-sugar-a-major-mediator-of-non-alcoholic-fatty-liver-disease
#10
REVIEW
Thomas Jensen, Manal F Abdelmalek, Shelby Sullivan, Kristen J Nadeau, Melanie Green, Carlos Roncal, Takahiko Nakagawa, Masanari Kuwabara, Yuka Sato, Duk-Hee Kang, Dean R Tolan, Laura G Sanchez-Lozada, Hugo R Rosen, Miguel A Lanaspa, Anna Mae Diehl, Richard J Johnson
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome; its rising prevalence parallels the rise in obesity and diabetes. Historically thought to result from overnutrition and a sedentary lifestyle, recent evidence suggests that diets high in sugar (from sucrose and/or high-fructose corn syrup [HFCS]) not only increase the risk of NAFLD, but also non-alcoholic steatohepatitis (NASH). Herein, we review the experimental and clinical evidence that fructose precipitates fat accumulation in the liver, due to both increased lipogenesis and impaired fat oxidation...
May 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29408463/bupropion-and-naltrexone-combination-alters-high-fructose-corn-syrup-self-administration-and-gene-expression-in-rats
#11
AnneMarie Levy, Stephen Daniels, Roger Hudson, Thomas Horman, Amanda Flynn, Yan Zhou, Francesco Leri
Contrave® is an adjunct pharmacotherapy for obesity that contains bupropion (BUP) and naltrexone (NTX). To further explore the psychopharmacology of this drug combination, male Sprague-Dawley rats were implanted with subcutaneous osmotic mini-pumps releasing: 40 mg/kg/day BUP, 4 mg/kg/day NTX, or 40 + 4 mg/kg/day BUP and NTX (BN). During 12 days of exposure, the animals were tested on operant intraoral self-administration (IOSA) of high fructose corn syrup (HFCS) on continuous (FR1) and progressive ratio (PR) schedules, on home cage drinking of HFCS, and on HFCS taste reactivity...
April 20, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/29366023/tdzd-8-attenuates-insulin-resistance-in-high-fructose-corn-syrup-fed-adolescent-rats
#12
Baris Alten, Metin Yesiltepe, Arwa Al-Bayrakdar, Sadik Taskin Tas, Canan Kursungoz, Ana Martinez, Mehmet Yildirim Sara
No abstract text is available yet for this article.
August 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29321950/manifestations-of-renal-impairment-in-fructose-induced-metabolic-syndrome
#13
Kameliya Bratoeva, George S Stoyanov, Albena Merdzhanova, Mariya Radanova
Introduction International studies show an increased incidence of chronic kidney disease (CKD) in patients with metabolic syndrome (MS). It is assumed that the major components of MS - obesity, insulin resistance, dyslipidemia, and hypertension - are linked to renal damage through the systemic release of several pro-inflammatory mediators, such as uric acid (UA), C-reactive protein (CRP), and generalized oxidative stress. The aim of the present study was to investigate the extent of kidney impairment and manifestations of dysfunction in rats with fructose-induced MS...
November 7, 2017: Curēus
https://www.readbyqxmd.com/read/29287121/high-fructose-corn-syrup-induces-metabolic-dysregulation-and-altered-dopamine-signaling-in-the-absence-of-obesity
#14
Allison M Meyers, Devry Mourra, Jeff A Beeler
The contribution of high fructose corn syrup (HFCS) to metabolic disorder and obesity, independent of high fat, energy-rich diets, is controversial. While high-fat diets are widely accepted as a rodent model of diet-induced obesity (DIO) and metabolic disorder, the value of HFCS alone as a rodent model of DIO is unclear. Impaired dopamine function is associated with obesity and high fat diet, but the effect of HFCS on the dopamine system has not been investigated. The objective of this study was to test the effect of HFCS on weight gain, glucose regulation, and evoked dopamine release using fast-scan cyclic voltammetry...
2017: PloS One
https://www.readbyqxmd.com/read/29248461/knockout-of-l-histidine-decarboxylase-prevents-cholangiocyte-damage-and-hepatic-fibrosis-in-mice-subjected-to-high-fat-diet-feeding-via-disrupted-histamine-leptin-signaling
#15
Lindsey Kennedy, Laura Hargrove, Jennifer Demieville, Jennifer M Bailey, Wasim Dar, Kishore Polireddy, Qingzheng Chen, Moises I Nevah Rubin, Amelia Sybenga, Sharon DeMorrow, Fanyin Meng, Lindsey Stockton, Gianfranco Alpini, Heather Francis
Feeding a high-fat diet (HFD) coupled with sugar, mimicking a Western diet, causes fatty liver disease in mice. Histamine induces biliary proliferation and fibrosis and regulates leptin signaling. Wild-type (WT) and l-histidine decarboxylase (Hdc-/- ) mice were fed a control diet or an HFD coupled with a high fructose corn syrup equivalent. Hematoxylin and eosin and Oil Red O staining were performed to determine steatosis. Biliary mass and cholangiocyte proliferation were evaluated by immunohistochemistry. Senescence and fibrosis were measured by quantitative PCR and immunohistochemistry...
March 2018: American Journal of Pathology
https://www.readbyqxmd.com/read/29219619/prenatal-and-early-life-fructose-fructose-containing-beverages-and-midchildhood-asthma
#16
Lakiea S Wright, Sheryl L Rifas-Shiman, Emily Oken, Augusto A Litonjua, Diane R Gold
RATIONALE: Cross-sectional studies have linked intake of high-fructose corn syrup-sweetened beverages with asthma in schoolchildren. OBJECTIVES: To examine associations of maternal prenatal and early childhood intake of sugar-sweetened beverages and fructose with current asthma in midchildhood (median age, 7.7 yr). METHODS: We assessed maternal pregnancy (first- and second-trimester average) and child (median age, 3.3 yr) intake of sugar-sweetened beverages and total fructose using food frequency questionnaires in 1,068 mother-child pairs from Project Viva, a prospective prebirth cohort...
February 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29207922/effect-of-steady-state-methadone-on-high-fructose-corn-syrup-consumption-in-rats
#17
Stephen Daniels, Mick Pratt, Yan Zhou, Francesco Leri
Patients undergoing methadone maintenance treatment self-report enhanced preferences for, and excessive consumption of, foods rich in sugar. However, it is unclear whether these are direct pharmacological effects of methadone or the consequences of metabolic dysfunctions induced by addiction to illicit opiates. Hence, the current study in drug-naïve male Sprague-Dawley rats explored the effects of steady-state methadone delivered by osmotic mini-pumps (13 days; 0, 10, 30 mg/kg/day) on consumption of rat chow and a palatable, sweet, liquid high fructose corn syrup solution...
February 2018: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/29193741/energy-expenditure-and-hormone-responses-in-humans-after-overeating-high-fructose-corn-syrup-versus-whole-wheat-foods
#18
Mostafa Ibrahim, Susan Bonfiglio, Mathias Schlögl, Karyne L Vinales, Paolo Piaggi, Colleen Venti, Mary Walter, Jonathan Krakoff, Marie S Thearle
OBJECTIVE: This study sought to understand how the dietary source of carbohydrates, either high-fructose corn syrup (HFCS) or complex carbohydrates, affects energy expenditure (EE) measures, appetitive sensations, and hormones during 24 hours of overfeeding. METHODS: Seventeen healthy participants with normal glucose regulation had 24-hour EE measures and fasting blood and 24-hour urine collection during four different 1-day diets, including an energy-balanced diet, fasting, and two 75% carbohydrate diets (5% fat) given at 200% of energy requirements with either HFCS or whole-wheat foods as the carbohydrate source...
January 2018: Obesity
https://www.readbyqxmd.com/read/29191195/maternal-dietary-free-or-bound-fructose-diversely-influence-developmental-programming-of-lipogenesis
#19
Armagan Aytug Yuruk, Reyhan Nergiz-Unal
BACKGROUND: Maternal dietary choices throughout preconception, pregnancy, and lactation irreversibly affect the development of fetal tissues and organs, known as fetal programming. Recommendations tend to emphasize reducing added sugars. However, the impact of maternal dietary free or bound fructose in added sugars on developmental programming of lipogenesis is unknown. METHODS: Virgin Sprague-Dawley rats were randomly divided into five groups. Rats were given feed and plain water (control) or water containing maltodextrin (vehicle), fructose, high-fructose corn syrup (HFCS) containing 55% fructose, sucrose (20% w/v) for 12 weeks before mating and throughout the pregnancy and lactation periods...
December 1, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29141949/microvascular-insulin-resistance-in-skeletal-muscle-and-brain-occurs-early-in-the-development-of-juvenile-obesity-in-pigs
#20
T Dylan Olver, Zachary I Grunewald, Thomas J Jurrissen, Rebecca E K MacPherson, Paul J LeBlanc, Teagan R Schnurbusch, Alana M Czajkowski, M Harold Laughlin, R Scott Rector, Shawn B Bender, Eric M Walters, Craig A Emter, Jaume Padilla
Impaired microvascular insulin signaling may develop before overt indices of microvascular endothelial dysfunction and represent an early pathological feature of adolescent obesity. Using a translational porcine model of juvenile obesity, we tested the hypotheses that in the early stages of obesity development, impaired insulin signaling manifests in skeletal muscle (triceps), brain (prefrontal cortex), and corresponding vasculatures, and that depressed insulin-induced vasodilation is reversible with acute inhibition of protein kinase Cβ (PKCβ)...
February 1, 2018: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
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