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https://www.readbyqxmd.com/read/28944377/mini-interfacial-fracture-toughness-of-a-multimode-adhesive-bonded-to-plasma-treated-dentin
#1
Ana Paula Almeida Ayres, Pong Pongprueksa, Jan De Munck, Cristina Parise Gré, Fábio Dupart Nascimento, Marcelo Giannini, Bart Van Meerbeek
PURPOSE: To investigate the bonding efficacy of a multimode adhesive to plasma-treated and -untreated (control) dentin using a mini-interfacial fracture toughness (mini-iFT) test. MATERIALS AND METHODS: Twenty human molars were used in a split-tooth design (n = 10). The adhesive Scotchbond Universal (SBU; 3M ESPE) was applied in etch-and-rinse (E&R) and self-etch (SE) modes. Mid-coronal dentin was exposed and covered with a standardized smear layer ground to 320 grit...
September 21, 2017: Journal of Adhesive Dentistry
https://www.readbyqxmd.com/read/28944373/misfit-of-implant-prostheses-and-its-impact-on-clinical-outcomes-definition-assessment-and-a-systematic-review-of-the-literature
#2
Joannis Katsoulis, Takuro Takeichi, Ana Sol Gaviria, Lukas Peter, Konstantinos Katsoulis
BACKGROUND AND AIM: Compromised fit between the contact surfaces of screw-retained implant-supported fixed dentures (IFDs) is thought to create uncontrolled strains in the prosthetic components and peri-implant tissues, thus evoking biological and technical complications such as bone loss, screw loosening, component fractures and, at worst, loss of implants or prostheses. The aim of this systematic review was to evaluate the impact of marginal misfit on the clinical outcomes of IFDs, and to elucidate definition and assessment methods for passive fit...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28944013/population-size-center-periphery-and-seed-dispersers-effects-on-the-genetic-diversity-and-population-structure-of-the-mediterranean-relict-shrub-cneorum-tricoccon
#3
Ana Lázaro-Nogal, Silvia Matesanz, Alfredo García-Fernández, Anna Traveset, Fernando Valladares
The effect of population size on population genetic diversity and structure has rarely been studied jointly with other factors such as the position of a population within the species' distribution range or the presence of mutualistic partners influencing dispersal. Understanding these determining factors for genetic variation is critical for conservation of relict plants that are generally suffering from genetic deterioration. Working with 16 populations of the vulnerable relict shrub Cneorum tricoccon throughout the majority of its western Mediterranean distribution range, and using nine polymorphic microsatellite markers, we examined the effects of periphery (peripheral vs...
September 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28943999/measuring-site-fidelity-and-spatial-segregation-within-animal-societies
#4
Thomas O Richardson, Luca Giuggioli, Nigel R Franks, Ana B Sendova-Franks
Animals often display a marked tendency to return to previously visited locations that contain important resources, such as water, food, or developing brood that must be provisioned. A considerable body of work has demonstrated that this tendency is strongly expressed in ants, which exhibit fidelity to particular sites both inside and outside the nest. However, thus far many studies of this phenomena have taken the approach of reducing an animal's trajectory to a summary statistic, such as the area it covers...
August 2017: Methods in Ecology and Evolution
https://www.readbyqxmd.com/read/28943445/the-effects-of-cissampelos-pareira-extract-on-envenomation-induced-by-bothropsdiporus-snake-venom
#5
Bárbara Ricciardi Verrastro, Ana Maria Torres, Gabriela Ricciardi, Pamela Teibler, Silvana Maruñak, Chiara Barnaba, Roberto Larcher, Giorgio Nicolini, Eduardo Dellacassa
ETHNOPHARMACOLOGICAL RELEVANCE: Ophidian accidents are a serious public health problem in Argentina; the Bothrops species is responsible for 97% of these accidents, and in particular, B. diporus is responsible for 80% of them. In the northeast of the country (Corrientes Provinces), Cissampelos pareira L. (Menispermaceae) is commonly used against the venom of B. diporus; its use is described in almost all ethnobotanical literature from countries where the plant grows,. AIM OF THE STUDY: In this study, the in vitro and in vivo antivenom activities of C...
September 21, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28943398/cold-sensing-trpm8-channel-participates-in-circadian-control-of-the-brown-adipose-tissue
#6
Maria Nathália Moraes, Leonardo Vinicius Monteiro de Assis, Felipe Dos Santos Henriques, Miguel Luiz Batista Junior, Ali D Güler, Ana Maria de Lauro Castrucci
Transient receptor potential (TRP) channels are known to regulate energy metabolism, and TRPM8 has become an interesting player in this context. Here we demonstrate the role of the cold sensor TRPM8 in the regulation of clock gene and clock controlled genes in brown adipose tissue (BAT). We investigated TrpM8 temporal profile in the eyes, suprachiasmatic nucleus and BAT; only BAT showed temporal variation of TrpM8 transcripts. Eyes from mice lacking TRPM8 lost the temporal profile of Per1 in LD cycle. This alteration in the ocular circadian physiology may explain the delay in the onset of locomotor activity in response to light pulse, as compared to wild type animals (WT)...
September 21, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28943392/an-integrative-analysis-of-chemically-induced-cirrhosis-associated-hepatocarcinogenesis-histological-biochemical-and-molecular-features
#7
Guilherme Ribeiro Romualdo, Tony Fernando Grassi, Renata Leme Goto, Mariana Baptista Tablas, Lucas Tadeu Bidinotto, Ana Angélica Henrique Fernandes, Bruno Cogliati, Luís Fernando Barbisan
This study aimed the integrative characterization of morphological, biochemical and molecular features of chemically-induced cirrhosis-associated hepatocarcinogenesis. Thus, male Wistar rats were submitted to a diethylnitrosamine (DEN)/thioacetamide (TAA)-induced model. Liver tissue was processed for global gene expression, histopathological and collagen evaluations; as well as immunohistochemical and oxidative stress analysis. Gene Ontology and functional analysis showed the upregulation of extracellular matrix deposition genes, such as collagen type I alpha 1 and 2 (Col1α1 and Col1α2) and tissue inhibitor of metalloproteinase 1 and 2 genes (Timp1 and Timp2)...
September 21, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28943110/therapies-for-mitochondrial-diseases-and-current-clinical-trials
#8
REVIEW
Ayman W El-Hattab, Ana Maria Zarante, Mohammed Almannai, Fernando Scaglia
Mitochondrial diseases are a clinically and genetically heterogeneous group of disorders that result from dysfunction of the mitochondrial oxidative phosphorylation due to molecular defects in genes encoding mitochondrial proteins. Despite the advances in molecular and biochemical methodologies leading to better understanding of the etiology and mechanism of these diseases, there are still no satisfactory therapies available for mitochondrial disorders. Treatment for mitochondrial diseases remains largely symptomatic and does not significantly alter the course of the disease...
September 18, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/28942955/neurocognitive-heterogeneity-in-older-adults-with-bipolar-disorders
#9
Diego J Martino, Eliana Marengo, Ana Igoa, Sergio A Strejilevich
The aim of this study was to estimate the prevalence of clinically significant cognitive deficits in a sample of euthymic older age bipolar disorder (OABD) patients, and its relationship with functional outcome. Sixty-six outpatients and 30 controls completed a neuropsychological battery and a measure of psychosocial functioning. There were 33.3% (CI95% 22-44%) of patients without clinically significant cognitive deficits, 36.4% (CI95% 24-48%) with selective deficits, and 30.3% (CI95% 19-41%) with global deficits...
September 14, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28942825/a-single-administration-of-fish-oil-inhibits-the-acute-inflammatory-response-in-rats
#10
Laura Lícia Milani de Arruda, Franciele Queiroz Ames, Damila Rodrigues de Morais, Renata Grespan, Ana Paula Maziero Gil, Maria Angélica Raffaini Covas Pereira Silva, Jesuí Vergílio Visentainer, Roberto Kenji Nakamura Cuman, Ciomar Aparecida Bersani-Amado
OBJECTIVE: To investigate the antiinflammatory effects of a single administration of fish oil (FO) on the acute inflammatory response. METHODS: The paw edema and pleurisy models were used to evaluate the effects of FO dissolved in olive oil (FOP) orally administered in a single dose in rats. Nitric oxide (NO) concentrations in the pleural exudate were performed according to the Griess method and the cytokine concentrations were determined by Luminex bead-based multiplex assay...
August 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28942698/neuroimaging-findings-using-transfontanellar-ultrasound-in-newborns-with-microcephaly-a-possible-association-with-congenital-zika-virus-infection
#11
Ana Sofia França Cruz Ximenes, Pedro Pires, Heron Werner, Patricia Mello Jungmann, Epitácio Leite Rolim Filho, Etiene Pedrosa Andrade, Roberto Souza Lemos, Alberto Borges Peixoto, Mohammad Zare Mehrjardi, Gabriele Tonni, Edward Araujo Júnior
OBJECTIVE: To determine the main neuroimaging findings of microcephalic newborns with possible Zika virus (ZIKV) intrauterine infection using transfontanellar cranial ultrasound. METHODS: We performed a retrospective study to describe the main neuroimaging in newborns with microcephaly and possible association with congenital ZIKV infection. Microcephaly was defined in the postnatal period using transfontanellar cranial examination which was performed using both two- (2D) and three-dimensional (3D) ultrasound...
September 24, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28942583/maleimido-proxyl-as-an-epr-spin-label-for-the-evaluation-of-conformational-changes-of-albumin
#12
Aleksandra Pavićević, Jinghui Luo, Ana Popović-Bijelić, Miloš Mojović
Albumin is the most abundant plasma protein and as such has been the subject of many studies using a variety of techniques. One of them, capable of monitoring the conformational changes and the binding capacity of proteins, is electron paramagnetic resonance spectroscopy (EPR) spin labeling. To date, albumin has been investigated using a number of different spin labels, mostly spin-labeled fatty acids (SLFAs). However, albumin can bind up to seven equivalents of fatty acids, making it difficult to determine which parts of the molecule undergo conformational changes...
September 23, 2017: European Biophysics Journal: EBJ
https://www.readbyqxmd.com/read/28942412/phace-syndrome-in-a-child-with-segmental-ih-of-face
#13
Carolina Vasconcelos Guimarães, Inês Candeias, Ana Pinheiro, Felicidade Trindade
No abstract text is available yet for this article.
September 23, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28942367/laughter-catches-attention
#14
Ana P Pinheiro, Carla Barros, Marcelo Dias, Sonja A Kotz
In social interactions, emotionally salient and sudden changes in vocal expressions attract attention. However, only a few studies examined how emotion and attention interact in voice processing. We investigated neutral, happy (laughs) and angry (growls) vocalizations in a modified oddball task. Participants silently counted the targets in each block and rated the valence and arousal of the vocalizations. A combined event-related potential and time-frequency analysis focused on the P3 and pre-stimulus alpha power to capture attention effects in response to unexpected events...
September 20, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28942258/genotoxic-potential-of-the-binary-mixture-of-cyanotoxins-microcystin-lr-and-cylindrospermopsin
#15
Klara Hercog, Sara Maisanaba, Metka Filipič, Ángeles Jos, Ana M Cameán, Bojana Žegura
Increased eutrophication of water bodies promotes cyanobacterial blooming that is hazardous due to the production of various bioactive compounds. Microcystin-LR (MCLR) is among the most widespread cyanotoxins classified as possible human carcinogen, while cylindrospermopsin (CYN) has only recently been recognized as health concern. Both cyanotoxins are genotoxic; however, the mechanisms of their action differ. They are ubiquitously present in water environment and are often detected together. Therefore, we studied genotoxic potential of the binary mixture of these cyanotoxins...
September 17, 2017: Chemosphere
https://www.readbyqxmd.com/read/28942204/can-flow-experiences-be-protective-of-work-related-depressive-symptoms-and-burnout-a-genetically-informative-approach
#16
Miriam A Mosing, Ana Butkovic, Fredrik Ullén
BACKGROUND: Genetic research on depression and burnout has focused mostly on adverse factors, although various aspects in daily life related to positive coping and well-being have been shown to potentially be protective. Using a large genetically informative sample, we aim to explore the potential relationship between flow proneness and work-related depressive symptoms and burnout. METHODS: About 10,000 Swedish twins filled in the Swedish Flow Proneness Questionnaire, a subscale of the Hopkins Symptom Checklist (SCL) depression scale, and the Emotional Exhaustion subscale of the Maslach Burnout Inventory-General Survey...
September 18, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28941993/dna-methylation-polymerase-chain-reaction-pcr-array-of-apoptosis-related-genes-in-pleomorphic-adenomas-of-the-salivary-glands
#17
Núbia Braga Pereira, Ana Carolina de Melo do Carmo, Kelma Campos, Sara Ferreira Dos Santos Costa, Marina Gonçalves Diniz, Ricardo Santiago Gomez, Carolina Cavalieri Gomes
OBJECTIVE: The aim of this study was to evaluate the DNA methylation profile in 22 apoptosis-related genes in pleomorphic adenomas (PAs) of the salivary glands, in comparison with normal salivary glands (NSGs), and to address the differences in methylation patterns between smaller and larger tumors. Additionally, we investigated if the hypermethylation of differentially methylated genes between NSGs and PAs impacted the messenger RNA (mRNA) transcription. DESIGN: Twenty-three fresh PA samples and 12 NSG samples were included...
August 31, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28941904/impact-of-growth-temperature-on-exopolysaccharide-production-and-probiotic-properties-of-lactobacillus-paracasei-strains-isolated-from-kefir-grains
#18
Ana A Bengoa, M Goretti Llamas, Carolina Iraporda, M Teresa Dueñas, Analía G Abraham, Graciela L Garrote
EPS-producing LAB are widely used in the dairy industry since these polymers improve the viscosity and texture of the products. Besides, EPS might be responsible for several health benefits attributed to probiotic strains. However, growth conditions (culture media, temperature, pH) could modify EPS production affecting both technological and probiotic properties. In this work, the influence of growth temperature on EPS production was evaluated, as well as the consequences of these changes in the probiotic properties of the strains...
February 2018: Food Microbiology
https://www.readbyqxmd.com/read/28941893/unravelling-the-contribution-of-the-penicillium-expansum-peste12-transcription-factor-to-virulence-during-apple-fruit-infection
#19
Paloma Sánchez-Torres, Laura Vilanova, Ana Rosa Ballester, Mario López-Pérez, Neus Teixidó, Inmaculada Viñas, Josep Usall, Luis González-Candelas, Rosario Torres
Blue mould disease caused by Penicillium expansum infection is one of the most important diseases of pome fruit accounting for important economic losses. In the present study, the PeSte12 transcription factor gene was identified, and deletant mutants were produced by gene replacement. Knockout mutants showed a significant decrease of virulence during apple fruit infection. Virulence was affected by the maturity stage of the fruit (immature, mature and over-mature), and disease severity was notably reduced when the apples were stored at 0 °C...
February 2018: Food Microbiology
https://www.readbyqxmd.com/read/28941716/blood-and-urine-cadmium-concentrations-and-walking-speed-in-middle-aged-and-older-u-s-adults
#20
Junghoon Kim, Esther Garcia-Esquinas, Ana Navas-Acien, Yoon-Hyeong Choi
Reduced physical performance is an important feature of aging, and walking speed is a valid measure of physical performance and mobility in older adults. Previous epidemiological studies suggest that cadmium exposure, even at low environmental levels, may contribute to vascular, musculoskeletal, and cognitive dysfunction, which may all be associated with reductions in physical performance. To this end, we investigated the associations of blood and urine cadmium concentrations with walking speed in middle-aged and older adults in the U...
September 20, 2017: Environmental Pollution
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