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https://www.readbyqxmd.com/read/27908449/gender-differences-in-the-association-between-childhood-sexual-abuse-and-risky-sexual-behaviours-a-systematic-review-and-meta-analysis
#1
Amanuel Alemu Abajobir, Steve Kisely, Joemer Calderon Maravilla, Gail Williams, Jake Moses Najman
This meta-analytic review examines the association between childhood sexual abuse and risky sexual behaviours with sub-group analyses by gender. Systematic searches of electronic databases including MEDLINE, PubMed, EMBASE, and PsycINFO were performed using key terms. We used a priori criteria to include high quality studies and control for heterogeneities across eligible studies. The review was registered with PROSPERO and used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines...
November 28, 2016: Child Abuse & Neglect
https://www.readbyqxmd.com/read/27906009/current-trends-and-intricacies-in-the-management-of-hiv-associated-pulmonary-tuberculosis
#2
REVIEW
Narendran Gopalan, Padmapriyadarsini Chandrasekaran, Soumya Swaminathan, Srikanth Tripathy
Human immunodeficiency virus (HIV) epidemic has undoubtedly increased the incidence of tuberculosis (TB) globally, posing a formidable global health challenge affecting 1.2 million cases. Pulmonary TB assumes utmost significance in the programmatic perspective as it is readily transmissible as well as easily diagnosable. HIV complicates every aspect of pulmonary tuberculosis from diagnosis to treatment, demanding a different approach to effectively tackle both the diseases. In order to control these converging epidemics, it is important to diagnose early, initiate appropriate therapy for both infections, prevent transmission and administer preventive therapy...
September 26, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27898570/are-centers-for-disease-control-and-prevention-guidelines-for-preexposure-prophylaxis-specific-enough-formulation-of-a-personalized-hiv-risk-score-for-pre-exposure-prophylaxis-initiation
#3
Matthew R Beymer, Robert E Weiss, Catherine A Sugar, Linda B Bourque, Gilbert C Gee, Donald E Morisky, Suzanne B Shu, Marjan Javanbakht, Robert K Bolan
BACKGROUND: Preexposure prophylaxis (PrEP) has emerged as a human immunodeficiency virus (HIV) prevention tool for populations at highest risk for HIV infection. Current US Centers for Disease Control and Prevention (CDC) guidelines for identifying PrEP candidates may not be specific enough to identify gay, bisexual, and other men who have sex with men (MSM) at the highest risk for HIV infection. We created an HIV risk score for HIV-negative MSM based on Syndemics Theory to develop a more targeted criterion for assessing PrEP candidacy...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27891291/knowledge-about-hiv-in-a-community-sample-of-urban-african-americans-in-the-south
#4
H Klein, C E Sterk, K W Elifson
PURPOSE: Race and HIV are intertwined in complex ways. African Americans, particularly those residing in the southern United States, are at great risk for contracting and subsequently transmitting HIV. Research on the extent to which members of this population understand the risks associated with engaging in specific behaviors is limited. This paper examines HIV knowledge among at-risk adult African American men and women and the factors associated with levels of HIV knowledge. METHODS: Based on a conceptual model derived from Social Disorganization Theory and Syndemics Theory, interviews were conducted between 2009 and 2011...
October 2016: Journal of AIDS & Clinical Research
https://www.readbyqxmd.com/read/27884181/prevalence-type-and-correlates-of-trauma-exposure-among-adolescent-men-and-women-in-soweto-south-africa-implications-for-hiv-prevention
#5
Kalysha Closson, Janan Janine Dietrich, Busi Nkala, Addy Musuku, Zishan Cui, Jason Chia, Glenda Gray, Nathan J Lachowsky, Robert S Hogg, Cari L Miller, Angela Kaida
BACKGROUND: Youth trauma exposure is associated with syndemic HIV risk. We measured lifetime prevalence, type, and correlates of trauma experience by gender among adolescents living in the HIV hyper-endemic setting of Soweto, South Africa. METHODS: Using data from the Botsha Bophelo Adolescent Health Survey (BBAHS), prevalence of "ever" experiencing a traumatic event among adolescents (aged 14-19) was assessed using a modified Traumatic Event Screening Inventory-Child (TESI-C) scale (19 items, study alpha = 0...
November 25, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27844298/prospective-effects-of-a-syndemic-on-hiv-and-sti-incidence-and-risk-behaviors-in-a-cohort-of-young-men-who-have-sex-with-men
#6
Brian Mustanski, Gregory Phillips, Daniel T Ryan, Gregory Swann, Lisa Kuhns, Rob Garofalo
Young men who have sex with men continue to be highly affected by HIV. To improve understanding of the role that multiple co-occurring health issues (i.e., syndemics) play in HIV acquisition, sophisticated modeling methods are needed. The purpose of this study was to use structural equation modeling to understand the structure of the syndemic and to test its longitudinal association with condomless anal sex. Data are from a longitudinal study of 450 YMSM. A primary syndemic component comprised of substance use, violence, and internalizing mental health factors significantly predicted the number of condomless anal sex partners in the full sample...
November 14, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/27752388/the-prevalence-of-and-factors-associated-with-alcohol-related-problems-in-a-community-sample-of-african-american-women
#7
Hugh Klein, Claire E Sterk, Kirk W Elifson
Purpose. This study examines the prevalence of alcohol-related problems, the factors underlying these problems, and whether or not there is evidence of syndemic effects in a community population of southern, urban African American women. Methods. Questionnaire-based interviews were conducted with 817 women, all African American, from 80 targeted census block groups in Atlanta, Georgia. Results. Most of the alcohol users (67.8%) experienced at least one problem as a result of their alcohol (ab)use, with most women experiencing two or more such problems...
2016: Journal of Addiction
https://www.readbyqxmd.com/read/27708678/current-trends-and-intricacies-in-the-management-of-hiv-associated-pulmonary-tuberculosis
#8
Narendran Gopalan, Padmapriyadarsini Chandrasekaran, Soumya Swaminathan, Srikanth Tripathy
Human immunodeficiency virus (HIV) epidemic has undoubtedly increased the incidence of tuberculosis (TB) globally, posing a formidable global health challenge affecting 1.2 million cases. Pulmonary TB assumes utmost significance in the programmatic perspective as it is readily transmissible as well as easily diagnosable. HIV complicates every aspect of pulmonary tuberculosis from diagnosis to treatment, demanding a different approach to effectively tackle both the diseases. In order to control these converging epidemics, it is important to diagnose early, initiate appropriate therapy for both infections, prevent transmission and administer preventive therapy...
2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27624727/using-syndemics-theory-to-investigate-risk-and-protective-factors-associated-with-condomless-sex-among-youth-living-with-hiv-in-17-u-s-cities
#9
Jacob J van den Berg, M Isabel Fernández, Joseph L Fava, Don Operario, Bret J Rudy, Patrick A Wilson
Identifying risk and protective factors associated with condomless sex among youth living with HIV is imperative for developing effective HIV prevention strategies. A cross-sectional sample of 1728 participants, 12-26 years of age, recruited from adolescent medicine clinics in 17 U.S. cities completed an audio-computer assisted self-interview with questions about their substance use, psychosocial factors, and attitudinal and behavioral factors. Guided by syndemics theory, a path analysis was used to assess the interrelations of these factors...
September 13, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/27590737/the-spread-of-zika-and-the-potential-for-global-arbovirus-syndemics
#10
Merrill Singer
It is estimated that over a million people die each year from infectious diseases of zoonotic origin and hundreds of millions suffer from these pervasive threats to human well-being. In light of the emergent global concern over the Zika virus, evidence that it has not one but two competent mosquito vector species in the Aedes family, and that both can be co-infected with other pathogens including dengue and chikungunya, this paper examines research suggesting the prospect of significant twenty-first-century outbreaks of arbovirus syndemics...
September 2, 2016: Global Public Health
https://www.readbyqxmd.com/read/27590004/beyond-the-syndemic-condom-negotiation-and-use-among-women-experiencing%C3%A2-partner-violence
#11
Courtney Peasant, Tami P Sullivan, Nicole H Weiss, Isabel Martinez, Jaimie P Meyer
BACKGROUND: HIV and sexually transmitted infections (STIs) disproportionately affect women who experience intimate partner violence (IPV). OBJECTIVE: The current study (1) applied a syndemic framework to study the collective effects of problematic drug use, hazardous drinking, depression, and posttraumatic stress disorder (PTSD) on fear of condom negotiation, condom negotiation, and condom use and (2) evaluated condom negotiation (controlling for fear of condom negotiation) as a mediator of the association between syndemic severity and condom use among low-income IPV-exposed women...
September 2, 2016: AIDS Care
https://www.readbyqxmd.com/read/27577087/modulation-of-the-immune-response-to-mycobacterium-tuberculosis-during-malaria-m-tuberculosis-co-infection
#12
R C Chukwuanukwu, C C Onyenekwe, L Martinez-Pomares, R Flynn, S Singh, G I Amilo, N R Agbakoba, J O Okoye
Tuberculosis (TB) causes significant morbidity and mortality on a global scale. The African region has 24% of the world's TB cases. TB overlaps with other infectious diseases such as malaria and HIV, which are also highly prevalent in the African region. TB is a leading cause of death among HIV-positive patients and co-infection with HIV and TB has been described as a syndemic. In view of the overlapping epidemiology of these diseases, it is important to understand the dynamics of the immune response to TB in the context of co-infection...
August 31, 2016: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/27571306/modulation-of-autoimmune-arthritis-severity-in-mice-by-apolipoprotein-e-apoe-and-cholesterol
#13
P Alvarez, F Genre, M Iglesias, J J Augustin, E Tamayo, J C Escolà-Gil, B Lavín, F Blanco-Vaca, R Merino, J Merino
Apolipoprotein E (ApoE) deficiency promoted an exacerbation of autoimmune arthritis in mice by inducing proinflammatory immune responses. In this study we analysed the contribution of hypercholesterolaemia and/or the absence of ApoE anti-inflammatory properties, unrelated to its function in the control of cholesterol metabolism, towards the acceleration of arthritis in these mutant animals. The induction and severity of collagen type II-induced arthritis (CIA) were compared for B10.RIII wild-type (WT), B10...
December 2016: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/27565027/puerto-rican-latina-youth-coming-out-to-talk-about-sexuality-and-identity
#14
Alice Fiddian-Green, Aline C Gubrium, Jeffery C Peterson
Public health efforts focused on Latina youth sexuality are most commonly framed by the syndemic of teen pregnancy and sexually transmitted infections, a narrow and often heteronormative focus that perpetuates silences that contribute to health inequities and overlooks the growing need for increased education, awareness, and support for lesbian, gay, bisexual, transgender, and questioning (LGBTQ) youth. This article presents findings from the project Let's Talk About Sex: Digital Storytelling for Puerto Rican Latina Youth, which used a culturally centered, narrative-based approach for analyzing participants' own specifications of sexual values and practices...
August 26, 2016: Health Communication
https://www.readbyqxmd.com/read/27530401/socioecological-factors-influencing-women-s-hiv-risk-in-the-united-states-qualitative-findings-from-the-women-s-hiv-seroincidence-study-hptn-064
#15
Paula M Frew, Kimberly Parker, Linda Vo, Danielle Haley, Ann O'Leary, Dazon Dixon Diallo, Carol E Golin, Irene Kuo, Lydia Soto-Torres, Jing Wang, Adaora A Adimora, Laura A Randall, Carlos Del Rio, Sally Hodder
BACKGROUND: We sought to understand the multilevel syndemic factors that are concurrently contributing to the HIV epidemic among women living in the US. We specifically examined community, network, dyadic, and individual factors to explain HIV vulnerability within a socioecological framework. METHODS: We gathered qualitative data (120 interviews and 31 focus groups) from a subset of women ages 18-44 years (N = 2,099) enrolled in the HPTN 064 HIV seroincidence estimation study across 10 US communities...
2016: BMC Public Health
https://www.readbyqxmd.com/read/27456040/someone-to-count-on-social-support-as-an-effect-modifier-of-viral-load-suppression-in-a-prospective-cohort-study
#16
M Reuel Friedman, Robert W S Coulter, Anthony J Silvestre, Ron Stall, Linda Teplin, Steve Shoptaw, Pamela J Surkan, Michael W Plankey
Though functional social support has been shown to serve as a protective factor for HIV viral load suppression in other populations, scant research has examined this relationship among men who have sex with men (MSM) in the United States. We assessed characteristics of social support, effects of social support on HIV viral load, and moderation by social support of the relationship between psychosocial indicators of a synergistic epidemic (syndemic) and HIV viral load. We analyzed longitudinal data from HIV-positive MSM using antiretroviral therapy who were enrolled in the Multicenter AIDS Cohort Study between 2002 and 2009 (n = 712)...
July 25, 2016: AIDS Care
https://www.readbyqxmd.com/read/27449272/syndemic-factors-associated-with-adult-sexual-hiv-risk-behaviors-in-a-sample-of-latino-men-who-have-sex-with-men-in-new-york-city
#17
Omar Martinez, Sonya Arreola, Elwin Wu, Miguel Muñoz-Laboy, Ethan Czuy Levine, Scott Edward Rutledge, Carolina Hausmann-Stabile, Larry Icard, Scott D Rhodes, Alex Carballo-Diéguez, Carlos E Rodríguez-Díaz, M Isabel Fernandez, Theo Sandfort
OBJECTIVE: Syndemic theory has been proposed as a framework for understanding the role of multiple risk factors driving the HIV epidemic among sexual and gender minority individuals. As yet, the framework has been relatively absent in research on Latinos/as. METHODS: We used logistic regression to assess relationships among cumulative syndemic conditions - including clinically significant depression, high-risk alcohol consumption, discrimination, and childhood sexual abuse - engagement with multiple partners and condomless anal intercourse (CAI) in a sample of 176 Latino men who have sex with men (MSM) in New York City...
September 1, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/27429185/global-epidemiology-of-hiv-infection-and-related-syndemics-affecting-transgender-people
#18
Tonia Poteat, Ayden Scheim, Jessica Xavier, Sari Reisner, Stefan Baral
INTRODUCTION: Transgender populations have been underrepresented in HIV epidemiologic studies and consequently in HIV prevention, care, and treatment programs. Since 2012, there has been a dramatic increase in research focused on transgender people. Studies highlight the burden of HIV and risk determinants, including intersecting stigmas, as drivers of syndemics among transgender populations. This review synthesizes the most recent global epidemiology of HIV infection and describes current gaps in research and interventions to inform prioritization of HIV research for transgender populations...
August 15, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27426424/associations-between-the-phosphatidylethanol-alcohol-biomarker-and-self-reported-alcohol-use-in-a-sample-of-hiv-infected-outpatient-drinkers-in-western-kenya
#19
Rebecca K Papas, Benson N Gakinya, Michael M Mwaniki, Alfred K Keter, Hana Lee, Michelle P Loxley, Debra A Klein, John E Sidle, Steve Martino, Joyce B Baliddawa, Kathryn L Schlaudt, Stephen A Maisto
BACKGROUND: To counteract the syndemics of HIV and alcohol in Sub-Saharan Africa, international collaborations have developed interventions to reduce alcohol consumption. Reliable and accurate methods are needed to estimate alcohol use outcomes. A direct alcohol biomarker called phosphatidylethanol (PEth) has been shown to validate heavy, daily drinking, but the literature indicates mixed results for moderate and nondaily drinkers, including among HIV-infected populations. This study examined the associations of the PEth biomarker with self-report alcohol use at 2 time points in 127 HIV-infected outpatient drinkers in western Kenya...
August 2016: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/27354845/beyond-the-pap-smear-gender-responsive-hiv-care-for-women
#20
REVIEW
Jaimie P Meyer, Julie A Womack, Britton Gibson
Women comprise nearly one-quarter of all people living with human immunodeficiency virus (HIV) in the U.S. and 20 percent of incident annual cases. Though women overall are more likely than men to be diagnosed with HIV and engage in care, they are as unlikely to successfully achieve viral suppression with antiretroviral therapy, suggesting gender-based disparities that should be addressed by gender-responsive policies and programs. Using the socioecological model of health and syndemics theory, we comprehensively reviewed published literature to evaluate reasons for and ways to address gender differences in HIV risk and treatment...
June 2016: Yale Journal of Biology and Medicine
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