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Sunil Jaiswal, Lu Fang, Vinit Jakhetiya, Jiahao Pang, Klaus Mueller, Oscar C Au
Color filter array (CFA) interpolation, or 3-band demosaicking, is a process of interpolating the missing color samples in each band to reconstruct a full color image. In this paper, we are concerned with the challenging problem of multispectral demosaicking, where each band is significantly undersampled due to the increment in the number of bands. Specifically, we demonstrate a frequency-domain analysis of the subsampled color-difference signal and observe that the conventional assumption of highly correlated spectral bands for estimating undersampled components is not precise...
December 1, 2016: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
Neal Bhutiani, William E Grizzle, Susan Galandiuk, Denis Otali, Gerald W Dryden, Nejat K Egilmez, Lacey R McNally
Currently, several non-invasive modalities, including MRI and PET, are being investigated to identify early intestinal inflammation, longitudinally monitor disease status, or detect dysplastic changes in patients with inflammatory bowel disease (IBD). Here, we assess the applicability and utility of multispectral optoacoustic tomography (MSOT) in evaluating the presence and severity of colitis. Mice with bacterial colitis demonstrated a temporally associated increase in mesenteric and colonic vascularity with an increase in mean signal intensity of oxygenated hemoglobin (p=0...
December 1, 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
Pei Shang, Fang Shen
The Multispectral Wide Field of View (WFV) camera on the Chinese GF-1 satellite, launched in 2013, has advantages of high spatial resolution (16 m), short revisit period (4 days) and wide scene swath (800 km) compared to the Landsat-8/OLI, which make it an ideal means of monitoring spatial-temporal changes of Suspended Particulate Matter (SPM) in large estuaries like the Yangtze Estuary. However, a lack of proper atmospheric correction methods has limited its application in water quality assessment. We propose an atmospheric correction method based on a look up table coupled by the atmosphere radiative transfer model (6S) and the water semi-empirical radiative transfer (SERT) model for inversion of water-leaving reflectance from GF-1 top-of-atmosphere radiance, and then retrieving SPM concentration from water-leaving radiance reflectance of the Yangtze Estuary and its adjacent sea...
November 25, 2016: Sensors
Yunwei Tang, Linhai Jing, Hui Li, Qingjie Liu, Qi Yan, Xiuxia Li
This study explores the ability of WorldView-2 (WV-2) imagery for bamboo mapping in a mountainous region in Sichuan Province, China. A large area of this place is covered by shadows in the image, and only a few sampled points derived were useful. In order to identify bamboos based on sparse training data, the sample size was expanded according to the reflectance of multispectral bands selected using the principal component analysis (PCA). Then, class separability based on the training data was calculated using a feature space optimization method to select the features for classification...
November 22, 2016: Sensors
C Fink, H A Haenssle
BACKGROUND: While the excisional biopsy and histological examination of suspicious lesions remains the current gold standard for diagnosing cutaneous melanoma (CM), there is a demand for more objective and non-invasive examination methods that may support clinicians in their decision when to biopsy or not. METHODS: This review is based on publications and guidelines retrieved by a selective search in PubMed and MEDLINE and focused on non-invasive diagnostic strategies for detecting melanoma...
November 22, 2016: Skin Research and Technology
E Natasha Stavros, Zachary Tane, Van R Kane, Sander Veraverbeke, Robert J McGaughey, James A Lutz, Carlos Ramirez, David Schimel
Megafires have lasting social, ecological, and economic impacts and are increasing in the western contiguous United States. Because of their infrequent nature, there is a limited sample of megafires to investigate their unique behavior, drivers, and relationship to forest management practices. One approach is to characterize critical information pre-, during, and post-fire using remote sensing. In August 2013, the Rim Fire burned 104,131 ha and in September 2014, the King Fire burned 39,545 ha. Both fires occurred in California's Sierra Nevada...
November 2016: Ecology
Hoover Rueda, Henry Arguello, Gonzalo R Arce
Compressive spectral imaging systems can reliably capture multispectral data using far fewer measurements than traditional scanning techniques. In this paper, a thin-film patterned filter array-based compressive spectral imager is demonstrated, including its optical design and implementation. The use of a patterned filter array entails a single-step three-dimensional spatial-spectral coding on the input data cube, which provides higher flexibility on the selection of voxels being multiplexed on the sensor. The patterned filter array is designed and fabricated with micrometer pitch size thin films, referred to as pixelated filters, with three different wavelengths...
November 20, 2016: Applied Optics
Yang Zhao, Jason R Maher, Mohamed M Ibrahim, Jennifer S Chien, Howard Levinson, Adam Wax
We have developed frequency domain multispectral multiple scattering low coherence interferometry (ms2/LCI) for deep imaging of absorption and scattering contrast. Using tissue-mimicking phantoms that match the full scattering phase function of human dermal tissue, we demonstrate that ms2/LCI can provide a signal/noise ratio (SNR) improvement of 15.4 dB over conventional OCT at an imaging depth of 1 mm. The enhanced SNR and penetration depth provided by ms2/LCI could be leveraged for a variety of clinical applications including the assessment of burn injuries where current clinical classification of severity only provides limited accuracy...
October 1, 2016: Biomedical Optics Express
Mohamed Lamine Askoura, Fabrice Vaudelle, Jean-Pierre L'Huillier
Knowledge of the optical properties of apple tissues such as skin and flesh is essential to better understand the light-tissue interaction process and to apply optical methods for apple quality inspection. This work aimed at estimating the anisotropy factor of thin skin and flesh samples extracted from three apple cultivars. The scattering-angular light distribution in each tissue sample was measured at four wavelengths (λ=633, 763, 784, and 852 nm), by means of a goniometer setup. Based on the recorded angular intensity I(θ,λ), the effective anisotropy factor g<sub>eff</sub> of each tissue type was first estimated using the mean statistics applied to the random variable cos θ...
November 10, 2016: Applied Optics
Wenlou Liu, Linwei Wang, Jiuyang Liu, Jingping Yuan, Jiamei Chen, Han Wu, Qingming Xiang, Guifang Yang, Yan Li
Despite the extensive application of multispectral imaging (MSI) in biomedical multidisciplinary researches, there is a paucity of data available regarding the implication of MSI in tumor prognosis prediction. We compared the behaviors of multispectral (MS) and conventional red-green-blue (RGB) images on assessment of human epidermal growth factor receptor 2 (HER2) immunohistochemistry to explore their impact on outcome in patients with invasive breast cancer (BC). Tissue microarrays containing 240 BC patients were introduced to compare the performance of MS and RGB imaging methods on the quantitative assessment of HER2 status and the prognostic value of 5-year disease-free survival (5-DFS)...
November 8, 2016: Translational Oncology
Peggy Stock, Kristin Weber
Technologies for in vivo imaging of the distribution and integration of cell transplants gain significance for the use of novel cell therapy approaches in regenerative medicine. Applied to adequate animal models, they provide information on the spatio-temporal engraftment and functional performance of the cells transplanted. This chapter includes a detailed description of the in vivo tracking of transplanted hepatocytes in rat liver including the conjugation of antibodies to fluorochromes for far red imaging using a multispectral optical imager...
2017: Methods in Molecular Biology
Jianwei Lin, Yuanjie Zheng, Wanzhen Jiao, Bojun Zhao, Shaoting Zhang, James Gee, Rui Xiao
Multispectral Imaging (MSI) produces a sequence of discrete spectral slices that penetrate different light-absorbing species or chromophores and is a noninvasive technology useful for the early detection of various retinal, optic nerve and choroidal diseases. However, eye movement during the image acquisition process may introduce spatial misalignment between MSI images. This potentially causes trouble in the manual/automatic interpretation of MSI, but still remains an unresolved problem to this date. To deal with this MSI misalignment problem, we present a method on the groupwise registration of sequential images from MSI of the retina and choroid...
October 31, 2016: Optics Express
Yiguang Wang, Chensu Wang, Yang Li, Gang Huang, Tian Zhao, Xinpeng Ma, Zhaohui Wang, Baran D Sumer, Michael A White, Jinming Gao
A multispectral hybrid nanotransistor consisting of modular fluorescent block copolymers with discrete and sharp pH transitions in one nanoparticluate system is presented. This nanotransistor probe allows digitized reporting of dynamic maturation at single-organelle resolution over time. This nanotechnology platform offers a powerful tool in fundamental studies of organelle biology, cell signaling in diseases characterized by pH dysregulation in the endosomes or lysosomes.
November 4, 2016: Advanced Materials
Katrin A Salva, Margo J Reeder, Rita Lloyd, Gary S Wood
Prolonged survival of lesional T cells plays a central role in the pathogenesis of T-cell-mediated dermatoses. We have recently shown that the ubiquitin ligase c-CBL is highly expressed in cutaneous T-cell lymphoma (CTCL) and that its knockdown increases activation-induced cell death, a key pathway for T-cell apoptosis. Here, we extend our work on c-CBL expression in malignant T cells to their nonneoplastic counterparts in benign inflammatory dermatoses. Immunohistochemical staining with anti-c-CBL antibody was performed on lesional biopsies from a total of 65 patients with atopic dermatitis, allergic contact dermatitis, pityriasis rosea, psoriasis vulgaris, lichen planus, mycosis fungoides (MF)/Sézary syndrome (SS) as well as on tonsil tissue from 5 individuals and on 5 human CTCL cell lines...
October 31, 2016: American Journal of Dermatopathology
S Y Chuah, A B E Attia, V Long, C J H Ho, P Malempati, C Y Fu, S J Ford, J S S Lee, W P Tan, D Razansky, M Olivo, S Thng
BACKGROUND: Recent advances in technology have enabled the development of various non-invasive skin imaging tools to aid real-time diagnosis of both benign and malignant skin tumours, minimizing the need for invasive skin biopsy. Multispectral optoacoustic tomography (MSOT) is a recently developed non-invasive imaging tool, which offers the unique capacity for high resolution three dimensional (3D) optical mapping of tissue by further delivering highly specific optical contrast from a depth of several millimetres to centimetres in living tissues...
November 2, 2016: Skin Research and Technology
Wei Shi, Yanxue Yin, Yao Wang, Bo Zhang, Pei Tan, Ting Jiang, Heng Mei, Jun Deng, Huafang Wang, Tao Guo, Zhiqing Pang, Yu Hu
Tumor requires tumor vasculature to supply oxygen and nutrients so as to support its continued growth, as well as provide a main route for metastatic spread. In this study, a TF-cascade-targeted strategy aiming to disrupt tumor blood vessels was developed by combination of TF-targeted HMME-loaded drug delivery system and PDT. PDT is a promising new modality in the treatment of cancers, which employs the interaction between a tumor-localizing photosensitizer and light of an appropriate wavelength to bring about ROS-induced cell death...
October 26, 2016: Oncotarget
Neil T Clancy, Srdjan Saso, Danail Stoyanov, Vincent Sauvage, David J Corless, Michael Boyd, David E Noakes, Meen-Yau Thum, Sadaf Ghaem-Maghami, James Richard Smith, Daniel S Elson
No abstract text is available yet for this article.
October 1, 2016: Journal of Biomedical Optics
Michael J Campbell, Frederick Baehner, Tess O'Meara, Ekene Ojukwu, Booyeon Han, Rita Mukhtar, Vickram Tandon, Max Endicott, Zelos Zhu, Jasmine Wong, Gregor Krings, Alfred Au, Joe W Gray, Laura Esserman
PURPOSE: The recent increase in the incidence of ductal carcinoma in situ (DCIS) has sparked debate over the classification and treatment of this disease. Although DCIS is considered a precursor lesion to invasive breast cancer, some DCIS may have more or less risk than is realized. In this study, we characterized the immune microenvironment in DCIS to determine if immune infiltrates are predictive of recurrence. METHODS: Fifty-two cases of high-grade DCIS (HG-DCIS), enriched for large lesions and a history of recurrence, were age matched with 65 cases of non-high-grade DCIS (nHG-DCIS)...
October 26, 2016: Breast Cancer Research and Treatment
Sébastien Rapinel, Laurence Hubert-Moy, Bernard Clément, Edward Maltby
Wetland functional assessment is commonly conducted based on field observations, and thus, is generally limited to small areas. However, there is often a need for wetland managers to obtain information on wetland functional performance over larger areas. For this purpose, we are proposing a new field-based functional assessment procedure in which wetland functions are evaluated and classified into hydrogeomorphic units according to a multi-criteria analysis approach. Wetland-related geographic information system layers derived from Earth observation data (LiDAR, multispectral and radar data) are used in this study for a large-scale functional evaluation...
December 0: Environmental Monitoring and Assessment
Doocheon Seo, Jaehong Oh, Changno Lee, Donghan Lee, Haejin Choi
Kompsat-3A, which was launched on 25 March 2015, is a sister spacecraft of the Kompsat-3 developed by the Korea Aerospace Research Institute (KARI). Kompsat-3A's AEISS-A (Advanced Electronic Image Scanning System-A) camera is similar to Kompsat-3's AEISS but it was designed to provide PAN (Panchromatic) resolution of 0.55 m, MS (multispectral) resolution of 2.20 m, and TIR (thermal infrared) at 5.5 m resolution. In this paper we present the geometric calibration and validation work of Kompsat-3A that was completed last year...
October 24, 2016: Sensors
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