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Mesenteric thrombosis

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https://www.readbyqxmd.com/read/29317949/superior-mesenteric-vein-thrombosis-in-a-patient-on-oral-contraceptive-pills
#1
Prashanth Rawla, Jeffrey Pradeep Raj, Krishna Chaitanya Thandra, Sathayajit S Bandaru
Abdominal pain is a common occurrence, and it may vary from subtle pain to very severe pain due to a variety of causes, some of which may even be life-threatening. It is commonly believed that a life-threatening cause is almost always very severe with regards to the symptomatology. However, here in this case report, we report an unusual case of abdominal pain due to superior mesenteric vein (SMV) thrombosis in an otherwise healthy lady who was on an oral contraceptive agent for the last 2 years. She presented with mild abdominal pain for 3 days, and a computed tomography scan of the abdomen which was done to rule out common surgical causes of abdominal pain revealed a thrombus in the SMV...
December 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/29310972/porto-mesenteric-venous-thrombosis-after-laparoscopic-sleeve-gastrectomy-a-case-report-and-systematic-review-of-the-104-cases
#2
Kerem Karaman, Mehmet Aziret, Ali Bal, Volkan Öter, Metin Ercan, Erdal Birol Bostancı
INTRODUCTION: Porto-mesenteric venous thrombosis (PMVT) is a rare but fatal complication after bariatric surgery. However, an increasing number of PMVT complications have been observed in the last years after laparoscopic sleeve gastrectomy (LSG) operations. CASE REPORT: A 35-year-old male was admitted to the emergency clinic in a septic status with a sudden once of abdominal pain and vomiting. The patient underwent laparoscopic sleeve gastrectomy (LSG) 15 days ago...
January 5, 2018: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/29309758/anti-thrombotic-efficacy-of-s007-867-pre-clinical-evaluation-in-experimental-models-of-thrombosis-in-vivo-and-in-vitro
#3
Ankita Misra, Prem Prakash, Hobby Aggarwal, Priyanka Dhankani, Sachin Kumar, Chandra Prakash Pandey, Nicholas Pugh, Dominique Bihan, Manoj Kumar Barthwal, Richard W Farndale, Dinesh Kumar Dikshit, Madhu Dikshit
Pharmacological inhibition of platelet collagen interaction is a promising therapeutic strategy to treat intra-vascular thrombosis. S007-867 is a novel synthetic inhibitor of collagen-induced platelet aggregation. It has shown better antithrombotic protection than aspirin and clopidogrel with minimal bleeding tendency in mice. The present study is aimed to systematically investigate the antithrombotic efficacy of S007-867 in comparison to aspirin and clopidogrel in vivo and to delineate its mechanism of action in vitro...
January 5, 2018: Biochemical Pharmacology
https://www.readbyqxmd.com/read/29308947/predictive-factors-of-thromboembolic-complications-in-patients-with-esophagogatric-adenocarcinoma-undergoing-preoperative-chemotherapy
#4
George Papaxoinis, Konstantinos Kamposioras, Theodora Germetaki, Jamie M J Weaver, Sofia Stamatopoulou, Magdy Nasralla, Zoe Kordatou, Vikki Owen-Holt, Alan Anthoney, Wasat Mansoor
BACKGROUND: Thromboembolic events (TEEs) represent a significant treatment and disease complication for cancer patients. In the present study we assessed the incidence of TEEs in patients receiving preoperative chemotherapy for esophagogastric adenocarcinoma. The risk factors for TEE development and their impact on prognosis were further analyzed. MATERIAL AND METHODS: Data from 590 patients with esophagogastric adenocarcinoma, who received preoperative epirubicin-cisplatin with capecitabine (ECX) or 5-fluorouracil (ECF) between 2009 and 2016 in three UK hospitals were retrospectively collected...
January 8, 2018: Acta Oncologica
https://www.readbyqxmd.com/read/29306522/visceral-thromboses-in-pancreas-adenocarcinoma-systematic-review
#5
REVIEW
Angel Mier Hicks, Antonio DeRosa, Michael Raj, Richard Do, Kenneth H Yu, Maeve A Lowery, Anna Varghese, Eileen M O'Reilly
Within gastrointestinal malignancies, primary hepatocellular carcinoma and pancreatic ductal adenocarcinoma (PDAC) are frequently associated with visceral thromboses (VT). Thrombus formation in the portal (PVT), mesenteric (MVT), or splenic vein (SVT) system leads to portal hypertension and intestinal ischemia. VT in PDAC may convey a risk of increased distal thrombosis and poses therapeutic uncertainty regarding the role of anticoagulation. An increasing number of reports describe VT associated with PDAC. It is possible that early diagnosis of these events may help reduce morbidity and speculatively improve oncologic outcomes...
December 12, 2017: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/29304524/amino-fucoidan-as-a-vector-for-rtpa-induced-fibrinolysis-in-experimental-thrombotic-events
#6
Radouane Ghebouli, Stephane Loyau, Murielle Maire, Pierre Saboural, Jean-Philippe Collet, Martine Jandrot-Perrus, Didier Letourneur, Frédéric Chaubet, Jean-Baptiste Michel
Acute ischaemic stroke, myocardial infarction and pulmonary embolism are the main causes of mortality and morbidity worldwide. Thrombolysis by intravenous injection of recombinant tissue plasminogen activator (rtPA) remains the most common non-interventional treatment to recanalize occluded vessels. However, this procedure is limited by significant drawbacks, including high doses and bleeding complications. Recent studies showed that fucoidan targets the intraluminal thrombus in vivo. We have developed a chimaera covalently linking fucoidan, able to target platelets within the thrombus, to dilysine, able to non-covalently bind rtPA...
January 2018: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29279232/portal-splenic-mesenteric-venous-thrombosis-in-a-patient-with-klinefelter-syndrome
#7
Macarena Larraín, Edgar Castillo-Regalado, Carlos Puig-Jove, Margarita Sala, Helena Masnou
No abstract text is available yet for this article.
December 23, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/29249391/risk-factors-of-secondary-intervention-for-type-ii-endoleaks-in-endovascular-aneurysm-repair-an-8-year-single-institution-study
#8
Up Huh, Chung Won Lee, Sung Woon Chung, Sang-Pil Kim, Seunghwan Song, Miju Bae, Jonggeun Lee, Chang Won Kim
BACKGROUND/OBJECTIVES: The natural history of type II endoleaks (T2ELs) is still not completely understood; however, it is widely accepted that those associated with aneurysmal sac growth are harmful. We aimed to review our experience with T2ELs in endovascular aneurysm repair (EVAR). METHODS: We retrospectively reviewed electronic medical records of all patients who underwent EVAR for infrarenal-type abdominal aortic aneurysms (AAAs) at a single institution from August 2007 to November 2015...
December 14, 2017: Asian Journal of Surgery
https://www.readbyqxmd.com/read/29242494/incidental-anatomic-finding-of-celiacomesenteric-trunk-associated-with-nutcracker-phenomenon-or-compression-of-the-left-renal-vein
#9
Joshua Peterson, Anthony N Hage, Stephan Diljak, Benjamin D Long, Daniel P Marcusa, John M Stribley, David W Brzezinski, Jonathan Eliason
BACKGROUND Celiacomesenteric trunk (CMT) is a very rare anatomic finding in which the celiac artery and the superior mesenteric artery (SMA) originate from the abdominal aorta through a common trunk. Clinical associations with CMT include arterial aneurysm, thrombosis, and celiac artery compression. However, an association between CMT and abdominal venous congestion caused by left renal vein compression, or 'nutcracker phenomenon,' has not been previously reported. CASE REPORT A 91-year-old woman, who died from a cerebrovascular accident (CVA), underwent a cadaveric examination at our medical school...
December 15, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29240055/-endovascular-treatment-of-acute-mesenteric-ischaemia-in-thrombosis-of-superior-mesenteric-artery
#10
A A Shchegolev, S A Papoian, A E Mitichkin, D G Gromov, A G Ishevskiĭ, A Iu Chevokin, M M Mutaev
The article deals with the problems related to acute impairment of mesenteric blood circulation, known as a nosological entity associated with an extremely high mortality rate. The authors point out that there are currently no common approaches to appropriate management of the pathology concerned and define the role of modern minimally invasive methods, which roentgenosurgical interventions belong to, making it possible to rapidly, safely and efficiently cope with the problem of thrombosis of mesenteric vessels, as well as to decrease lethality and improve the prognosis in this cohort of patients...
2017: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29231253/internal-venous-anomalies-in-patients-with-a-genital-venous-malformation
#11
Caitlin M Peterman, Patricia S Todd, Anna P Lillis, Steven J Fishman, Marilyn G Liang
BACKGROUND: Cutaneous venous malformation (VM) can be associated with internal vascular anomalies. Our objective was to investigate the frequency of internal vascular anomalies in patients with an isolated genital venous malformation to assess the utility of screening for internal findings. METHODS: We retrospectively reviewed our Vascular Anomalies Center database for patients with a focal genital venous malformation presenting between 1999 and 2016. Abdominal and pelvic imaging reports were reviewed for internal vascular anomalies...
December 12, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29217335/rivaroxaban-and-apixaban-for-initial-treatment-of-acute-venous-thromboembolism-of-atypical-location
#12
Dawid T Janczak, Malgorzata K Mimier, Robert D McBane, Patrick S Kamath, Benjamin S Simmons, Dalene M Bott-Kitslaar, Charles J Lenz, Emily R Vargas, David O Hodge, Waldemar E Wysokinski
OBJECTIVES: To assess the outcome of direct oral anticoagulants (DOACs), specifically Xa inhibitors: rivaroxaban and apixaban, for the treatment of venous thromboembolism (VTE) of atypical location (VTE-AL), portal, mesenteric, hepatic, splenic, gonadal, renal, and cerebral veins, prospectively collected data of Mayo Thrombophilia Clinic Registry were used. METHODS: Patients with acute VTE-AL treated with DOACs, enrolled between March 1, 2013, and February 1, 2017, were compared with patients with VTE of typical location (VTE-TL: deep vein thrombosis of extremities and/or pulmonary embolism) receiving DOACs and with patients with VTE-AL treated with enoxaparin...
December 4, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/29211374/-splanchnic-vein-thrombosis
#13
Bobby Gouin, Helia Robert-Ebadi, Alessandro Casini, Yan Beauverd, Pierre Fontana, Marc Righini, Laure Elkrief
Splanchnic vein thromboses include thrombosis of the portal venous system (including the portal, mesenteric and splenic vein) and hepatic vein thrombosis (also called Budd-Chiari syndrome). They are rare manifestations of venous thromboembolism. These thromboses are frequently associated with local or systemic factors. The therapeutic approach is often complex due to heterogeneity of patients and limited available data in the literature. The cornerstone of treatment is anticoagulation. However, the bleeding risk, related to portal hypertension, should be accurately assessed to individualize the treatment...
December 6, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29205015/treatment-options-for-acute-mesenteric-ischemia-have-improved
#14
Jussi M Kärkkäinen, Hannu Manninen, Hannu Paajanen
Acute mesenteric ischemia resulting from mesenteric arterial thrombosis is a life-threatening cardiovascular complication with symptoms ranging from sudden-onset abdominal pain to vague symptoms of several days' duration. Although contrast-enhanced computed tomography is an excellent diagnostic tool, detection of the disease before the development of permanent intestinal injury is still difficult. Endovascular treatment is usually successful in restoring intestinal blood flow acutely. Chronic mesenteric ischemia requires urgent detection and therapy in order to prevent irreversible intestinal ischemia...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29202678/approach-to-thrombosis-at-unusual-sites-splanchnic-and-cerebral-vein-thrombosis
#15
REVIEW
Nicoletta Riva, Walter Ageno
Splanchnic vein thrombosis (SVT) and cerebral vein thrombosis (CVT) are two manifestations of unusual site venous thromboembolism (VTE). SVT includes thrombosis in the portal, mesenteric or splenic veins, and the Budd-Chiari syndrome. CVT encompasses thrombosis of the dural venous sinuses and thrombosis of the cerebral veins. Unusual site VTE often represents a diagnostic and therapeutic challenge because of the heterogeneity in clinical presentation, the limited evidence available in the literature on the acute and long-term prognosis of these diseases, and the lack of large randomized controlled trials evaluating different treatment options...
December 2017: Vascular Medicine
https://www.readbyqxmd.com/read/29202584/treatment-of-acute-portomesenteric-venous-thrombosis-with-thrombectomy-through-a-transjugular-intrahepatic-portosystemic-shunt-a-single-center-experience
#16
Kerstin Rosenqvist, Charlotte Ebeling Barbier, Fredrik Rorsman, Per Sangfelt, Rickard Nyman
Background Acute portomesenteric venous thrombosis (PMVT) is a potentially life-threatening condition and urgent treatment is required. Purpose To retrospectively evaluate the efficacy and safety of treating acute PMVT by the creation of a transjugular intrahepatic portosystemic shunt (TIPS) followed by thrombectomy. Material and Methods Six patients (all men, age range = 39-51 years) presenting with acute PMVT were treated with transjugular thrombectomy (TT) through a TIPS created in the same session. The intervention included iterated venography through the TIPS one to three times within the first week after diagnosis and repeated thrombectomy if needed (n = 5)...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29202352/intrahepatic-portal-vein-thrombosis-due-to-postoperative-biliary-obstruction-successfully-treated-by-a-partial-thrombectomy-combined-with-thrombolytic-drug-therapy
#17
Naoya Imamura, Atsushi Nanashima, Yuki Tsuchimochi, Takeomi Hamada, Koichi Yano, Masahide Hiyoshi, Yoshiro Fujii, Kunihide Nakamura
INTRODUCTION: This case report aims to inform pancreatic surgeons about our perioperative management of intrahepatic portal vein thrombosis caused by an obstruction of hepaticojejunostomy (HJ) after pancreaticoduodenectomy (PD). CASE PRESENTATION: A 65-year-old woman was diagnosed with pancreas head carcinoma involving the superior mesenteric vein (SMV). Pancreaticoduodenectomy combined with SMV resection was followed by HJ. Twisting or narrowing was not evident during anastomosis...
November 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29176370/percutaneous-transhepatic-y-shaped-stent-placement-in-portal-superior-mesenteric-vein-tumor-thrombosis-before-right-colectomy
#18
Antonio Pesce, Andrea Boncoraglio, Antonio Basile, Stefano Puleo
Portal-mesenteric tumor thrombosis represents a rare finding in patients with colorectal cancers. To our knowledge this is the first report of a patient diagnosed as having a wide stenosing right colon cancer with portal-superior mesenteric vein tumor thrombosis at the time of diagnosis, who was treated before surgery by positioning a percutaneous transhepatic Y-shaped stent through the main portal vein and the superior mesenteric vein. Percutaneous interventional procedures have gained worldwide acceptance for improving the symptoms of portal hypertension, because of their minimal invasiveness and high success rates with low number of complications...
November 15, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/29155940/stented-balloon-fenestration-before-entry-repair-using-the-frozen-elephant-trunk-technique-for-chronic-aortic-dissection
#19
Naomichi Uchida, Yoshitaka Yamane, Tomokuni Furukawa
Endovascular fenestration on the abdominal aorta is effective for preventing visceral malperfusion in aortic dissection. We report a case of stented balloon fenestration before residual entry repair using the frozen elephant trunk technique for chronic aneurysmal dissection after ascending aortic replacement for DeBakey I aortic dissection. We recognized poor communication between the true lumen and false lumen in the abdominal aorta, and visceral perfusion depended almost entirely on the proximal large entry...
October 9, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29151701/clinical-outcomes-of-transcatheter-selective-superior-mesenteric-artery-urokinase-infusion-therapy-vs-transjugular-intrahepatic-portosystemic-shunt-in-patients-with-cirrhosis-and-acute-portal-vein-thrombosis
#20
Ting-Ting Jiang, Xiao-Ping Luo, Jian-Ming Sun, Jian Gao
AIM: To compare the outcomes of transcatheter superior mesenteric artery (SMA) urokinase infusion and transjugular intrahepatic portosystemic shunt (TIPS) for acute portal vein thrombosis (PVT) in cirrhosis. METHODS: From January 2013 to December 2014, patients with liver cirrhosis and acute symptomatic PVT who met the inclusion criteria were randomly assigned to either an SMA group or a TIPS group. The two groups accepted transcatheter selective SMA urokinase infusion therapy and TIPS, respectively...
November 7, 2017: World Journal of Gastroenterology: WJG
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