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https://www.readbyqxmd.com/read/29318861/-clinical-trials-for-treatment-of-allergic-rhinitis-with-heat-sensitive-moxibustion-and-its-regularity-of-heat-sensitization-acupoint-distribution
#1
Yu-Fen Lin, Jian-Min Lu, Yan-Na Su, Ze-Bin Zhong, Zuo-Dan Zhang
OBJECTIVE: To observe the clinical effect of heat sensitive moxibustion (HSM) and its regularity of acupoint heat-sensitization in the treatment of allergic rhinitis (AR) patients. METHODS: Seventy patients with AR were randomly divided into HSM and manual acupuncture groups (n=35/group). For patients of the HSM group, acupoints Yintang (EX-HN 3), bilateral Yingxiang (LI 20), Shangxing (GV 23), Tongtian (BL 7), Feishu (BL 13), Hegu (LI 4), etc. were used, and for patients of the manual acupuncture group, bilateral LI 20 and LI 4, Bitong (EX-HN 8) and EX-HN 3 were needled and stimulated with uniform reinforcing-reducing needling method...
December 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29316784/clusterin-induces-muc5ac-expression-via-activation-of-nf-%C3%AE%C2%BAb-in-human-airway-epithelial-cells
#2
Chang Hoon Bae, Hyung Gyun Na, Yoon Seok Choi, Si-Youn Song, Yong-Dae Kim
Objectives: Clusterin (CLU) is known as apolipoprotein J, and has three isoforms with different biological functions. CLU is associated with various diseases such as Alzheimer disease, atherosclerosis, and some malignancies. Recent studies report an association of CLU with inflammation and immune response in inflammatory airway diseases. However, the effect of CLU on mucin secretion of airway epithelial cells has not yet been understood. Therefore, the effect and brief signaling pathway of CLU on MUC5AC (as a major secreted mucin) expression were investigated in human airway epithelial cells...
January 11, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29306235/expression-profiles-of-cd11b-galectin-1-beclin-1-and-caspase-3-in-nasal-polyposis
#3
Alper Dilci, Nuray Varol, İlker Kılıçcıoğlu, Ece Konac, Utku Aydil, Yusuf Kızıl, Sabri Uslu
Background/aim: Nasal polyposis is a chronic inflammatory disease affecting the paranasal sinuses and nasal mucosae. It is thought that genetic and molecular mechanisms in inflammatory and apoptotic pathways are the main factors in the etiopathogenesis of nasal polyposis. The aim of this study was to investigate the expression patterns of CD11b, galectin-1, beclin-1, and caspase-3 in nasal polyps.Materials and methods: The mRNA expression levels of CD11b, galectin-1, beclin-1, and caspase-3 protein and western blot analysis of caspase-3 protein were evaluated in inferior turbinate mucosae and nasal polyp tissues...
December 19, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29287870/postoperative-bradycardia-following-adenotonsillectomy-in-children-does-intraoperative-administration-of-dexmedetomidine-play-a-role
#4
Benjamin Bush, Joseph D Tobias, Chen Lin, James Ruda, Kris R Jatana, Garth Essig, Jennifer Cooper, Dmitry Tumin, Charles A Elmaraghy
INTRODUCTION: Dexmedetomidine is a novel pharmacologic agent that has become a frequently used adjunct during care of pediatric patients with obstructive sleep apnea (OSA) undergoing tonsillectomy. While generally safe and effective, dexmedetomidine is associated with adverse effects of hypotension and bradycardia from its central sympatholytic effects. Due to safety concerns, our institution routinely admits patients with OSA for overnight cardiorespiratory monitoring following tonsillectomy...
January 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29280492/unexpected-prominent-tension-pneumosella-five-years-after-endoscopic-endonasal-transsphenoidal-surgery
#5
Tatsuma Matsuda, Kentaro Horiguchi, Yoshinori Higuchi, Toyoyuki Hanazawa, Yoshitaka Okamoto, Yasuo Iwadate
Tension pneumosella (TP) is a rare entity reported as the invagination of the sphenoid sinus mucosa into the skull base after endonasal transsphenoidal surgery. Few studies have reported on TP, and in these studies, invagination is confined to either the intrasellar or suprasellar area. We encountered a case of unexpected prominent TP toward the intracranial space 5 years after endoscopic endonasal transsphenoidal surgery (EETS) for a nonfunctioning pituitary adenoma. In addition, we present a hypothesis of the underlying mechanism by a pressure gradient change between the extracranial and intracranial space in TP formation...
December 27, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29260781/-the-substantiation-for-simultaneous-rhinoplasty-and-correction-of-the-intranasal-structures-in-the-patients-presenting-with-the-combination-of-pathology-of-the-nasal-cavity-and-disfigurement-of-the-shape-of-the-nose
#6
T A Aleksanyan
The objective of the present work was to evaluate the effectiveness of rhinoplasty performed in the combination with the correction of the intranasal structures. The study included the comparison of intra- and post-operative characteristics of rhinoplasty carried out with and without correction of the intranasal structures in 374 patients presenting with the combination of pathology of the nasal cavity and disfigurement of the shape of the nose. It was shown that the simultaneous surgical interventions are not accompanied by a significant increase in the frequency of intra- and post-operative complications in comparison with rhinoplastic surgery alone; nor do they require additional time expenditures...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/29239925/the-validity-of-training-endoscopic-sinus-and-skull-base-surgery-techniques-on-the-experimental-head-model
#7
Ranko Mladina, Neven Skitarelić, Cemal Cingi, Lei Chen, Nuray Bayar Muluk
OBJECTIVES: The aim of this study was to better understand the usual learning curve in acquiring endonasal endoscopic sinus and skull base surgery (ESSBS) techniques during the novice training on the lamb's head model. METHODS: Ten novices were asked to perform 10 bilateral dissections on the particular lamb's head each. The dissections were uniform, consisted of 10 well-defined steps, beginning from the simple removal of the inferior turbinate, and ending with more complicated procedures like cerebrospinal fluid leak repair, Draf 3 procedure for the frontal sinus and elevation of the nasal septal flap...
December 12, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29237344/epithelial-myoepithelial-carcinoma-of-the-nasal-cavity-clinical-histopathological-and-immunohistochemical-distinction-of-a-case-report
#8
Sally Nguyen, Marjorie Perron, Sylvie Nadeau, Alexandre Nakao Odashiro, Marie-Noëlle Corriveau
BACKGROUND: Epithelial myoepithelial carcinomas (EMCs) are rare low-grade salivary gland tumors. Here, we report the case of a 75-year-old man presenting with an oncocytic variant of EMC of the nasal cavity, initially diagnosed as an oncocytoma. METHODS: Our patient underwent functional sinus surgery in 2012. On pathology, an oncocytic neoplasm was found in the right nasal cavity, characterized by fragments of uniform bland oncocytic cells with bilayered arrangement of nuclei...
December 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29236279/the-maxillary-nerve-block-for-in-office-hybrid-balloon-sinus-dilation-procedures-a-preliminary-study
#9
Gary J Nishioka
Transitioning of rhinologic procedures from the operating room to the office setting in selected patients is a rising trend. An effective pain-control, patient-preparation protocol is essential, especially with advanced in-office rhinologic procedures such as hybrid balloon sinus dilation (BSD), in which other procedures such as ethmoidectomy, turbinate reduction, and other procedures are concomitantly performed. A regimen using oral sedation, topical tetracaine gel, topical tetracaine/epinephrine-soaked cottonoid packs, and intranasal local infiltrative anesthesia can vary significantly in effectiveness and be suboptimal at times (as determined by using treated patients as historical controls)...
December 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29236276/5-ht7-receptors-are-over-expressed-in-patients-with-nasal-polyps
#10
Muhammed Yayla, Zekai Halici, Duygu Kose, Arzu Tatar, Mustafa Sitki Gozeler
Nasal polyposis (NP) is an inflammatory disease of the paranasal sinuses and nasal cavity. The primary purpose of our study is to determine the expression of 5-HT7 receptors both in nasal polyps and in healthy tissue in the nasal cavity. The subsequent aim is to compare the expression of 5-HT7 receptors in patients with NP and in inferior turbinate tissue (control). The study included 60 participants (40 with NP and 20 controls) aged 35 to 62 years. Nasal polyp samples were collected from all patients and relative 5-HT7 receptor expression analyses were performed...
December 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29233518/nasal-patency-and-otorhinolaryngologic-orofacial-features-in-children
#11
Jovana de Moura Milanesi, Luana Cristina Berwig, Luiz Henrique Schuch, Rodrigo Agne Ritzel, Ana Maria Toniolo da Silva, Eliane Castilhos Rodrigues Corrêa
INTRODUCTION: Nasal obstruction is a common symptom in childhood, related to rhinitis and pharyngeal tonsil hypertrophy. In the presence of nasal obstruction, nasal patency may be reduced, and nasal breathing is replaced by mouth breathing. Orofacial and otorhinolaryngologic changes are related to this breathing mode. Objective evaluation of upper airways may be obtained through nasal patency measurement. OBJECTIVE: To compare nasal patency and otorhinolaryngologic-orofacial features in children...
November 21, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29226824/mdixon-based-texture-analysis-of-an-intraosseous-lipoma-a-case-report-and-current-review-for-the-dental-clinician
#12
Kyung Mi Lee, Hyug-Gi Kim, Yeon-Hee Lee, Eui Jong Kim
An intraosseous lipoma is a rare histologic variant of lipoma, accounting for only 0.1% of all primary bone tumors. This may not be the actual incidence because most of these lesions are frequently asymptomatic, but imaging modalities, such as computed tomography or magnetic resonance imaging (MRI) seem to have increased the detection rate. Lipoma occasionally undergoes osseous metaplasia and becomes an osseous lipoma. Although there are numerous papers discussing intraosseous lipoma and some authors have tried to differentiate lipomas from osseous lipomas, there is still a great deal of confusion with regard to characteristic radiologic features and the use of terms...
December 6, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29216475/long-face-dentofacial-deformities-occlusion-and-facial-esthetic-surgical-outcomes
#13
Jeffrey C Posnick, Samuel Liu, Timothy J Tremont
PURPOSE: The purpose of this study was to document malocclusion and facial dysmorphology in a series of patients with long face (LF) and chronic obstructive nasal breathing before treatment and the outcomes after bimaxillary orthognathic, osseous genioplasty, and intranasal surgery. MATERIALS AND METHODS: A retrospective cohort study of patients with LF undergoing bimaxillary, chin, and intranasal (septoplasty and inferior turbinate reduction) surgery was implemented...
December 4, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29204589/hyoid-myotomy-and-suspension-without-simultaneous-palate-or-tongue-base-surgery%C3%A2-for-obstructive-sleep-apnea
#14
Adrian A Ong, Jonathan Buttram, Shaun A Nguyen, Dustin Platter, Michael R Abidin, M Boyd Gillespie
Objective: Determine the effects of hyoid myotomy and suspension (HMS) without concurrent palatal or tongue base sleep surgery for obstructive sleep apnea (OSA). Method: Patients with OSA treated with HMS were identified using CPT code (21685) at an academic and private sleep surgery clinic. Those who underwent concurrent palatal or tongue base sleep surgery were excluded. Outcomes included simultaneous procedures, apnea-hypopnea index (AHI), lowest oxyhemoglobin saturation (LSAT), and Epworth Sleepiness Scale (ESS)...
June 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204588/radiofrequency-ablation-of-the-lateral-palatal-space-for-snoring
#15
B Tucker Woodson, Kent S Tadokoro, Stuart G MacKay
Objective: Pilot study to examine the effect of radiofrequency ablation (RFA) of the lateral palatal fat pad in patients with socially-disruptive snoring. Method: Snoring outcomes and complications were compared between a group of patients with treated with RFA ablation of the lateral soft palate fat pad with or without inferior turbinate reduction (8 patients) and another group undergoing inferior turbinate reduction alone (12 patients). Results: Snoring loudness and bothersomeness improved in the palate but not inferior turbinate group...
June 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204578/nasal-septum-suture-combined-with-inferior-turbinate-coblation-after-septoplasty-does-it-improve-quality-of-life-and-reduce-complications
#16
Hui Li, Min Wang, Yu-Xiao Wu, Szuchi Wang, Zhi-Min Xing
Objective: Nasal packing is routinely applied after septoplasty. Patients, however, report feeling very uncomfortable while the packing is in place. The aim of this study was to compare the effects of nasal septum suture combined with inferior turbinate coblation to the effects of nasal packing after septoplasty. Methods: In this study, 135 patients undergoing septoplasty were divided into 3 groups: group 1 patients had microdebrider with packing, group 2 received coblation with packing and group 3 had coblation with suture...
March 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29182682/inferior-immunogenicity-and-efficacy-of-respiratory-syncytial-virus-fusion-protein-based-subunit-vaccine-candidates-in-aged-versus-young-mice
#17
Corinne Cayatte, Angie Snell Bennett, Gaurav Manohar Rajani, Leigh Hostetler, Sean K Maynard, Michelle Lazzaro, Patrick McTamney, Kuishu Ren, Terrence O'Day, Michael P McCarthy, Kirsten Schneider-Ohrum
Respiratory syncytial virus (RSV) is recognized as an important cause of lower and upper respiratory tract infections in older adults, and a successful vaccine would substantially lower morbidity and mortality in this age group. Recently, two vaccine candidates based on soluble purified glycoprotein F (RSV F), either alone or adjuvanted with glucopyranosyl lipid A formulated in a stable emulsion (GLA-SE), failed to reach their primary endpoints in clinical efficacy studies, despite demonstrating the desired immunogenicity profile and efficacy in young rodent models...
2017: PloS One
https://www.readbyqxmd.com/read/29174644/does-the-reduction-of-inferior-turbinate-affect-lower-airway-functions
#18
Ozlem Unsal, Mehtap Ozkahraman, Mufide Arzu Ozkarafakili, Meltem Akpinar, Arzu Yasemin Korkut, Senem Kurt Dizdar, Berna Uslu Coskun
INTRODUCTION: Although the nose and lungs are separate organs, numerous studies have reported that the entire respiratory system can be considered as a single anatomical and functional unit. The upper and lower airways affect each other either directly or through reflex mechanisms. OBJECTIVE: In this study, we aimed to evaluate the effects of the radiofrequency ablation of persistent inferior turbinate hypertrophy on nasal and pulmonary function. METHODS: Twenty-seven patients with bilateral persistent inferior turbinate hypertrophy without septal deviation were included in this study...
November 6, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29165896/investigation-of-the-abnormal-nasal-aerodynamics-and-trigeminal-functions-among-empty-nose-syndrome-patients
#19
Chengyu Li, Alexander A Farag, Guillermo Maza, Sam McGhee, Michael A Ciccone, Bhakthi Deshpande, Edmund A Pribitkin, Bradley A Otto, Kai Zhao
BACKGROUND: Abnormal nasal aerodynamics or trigeminal functions have been frequently implicated in the symptomology of empty nose syndrome (ENS), yet with limited evidence. METHODS: Individual computed tomography (CT)-based computational fluid dynamics (CFD) was applied to 27 ENS patients to simulate their nasal aerodynamics and compared with 42 healthy controls. Patients' symptoms were confirmed with Empty Nose Syndrome 6-item Questionnaire (ENS6Q), 22-item Sino-Nasal Outcome Test (SNOT-22), and Nasal Obstruction Symptom Evaluation (NOSE) scores...
November 22, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29159751/septal-and-turbinate-surgery-is-overnight-essential
#20
Ana Sousa Menezes, Joana R Guimarães, Miguel Breda, Vicente Vieira, Luís Dias
INTRODUCTION: The performance of septoplasty and turbinate surgery in an outpatient basis is an increasingly established practice, although is still a controversial topic. METHODS: Retrospective analysis of 227 patients who underwent septoplasty ± inferior and/or middle turbinoplasty. Demographic, clinical, surgical, and anesthetic data were collected. Our primary outcomes were rates of perioperative complications, prolongation of hospital stay (PHS), unexpected hospital revisits (UHR), or readmissions within 30 days of surgery...
November 20, 2017: European Archives of Oto-rhino-laryngology
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