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Inferior turbinate

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https://www.readbyqxmd.com/read/28059551/wnt-signaling-in-chronic-rhinosinusitis-with-nasal-polyps
#1
Robert Böscke, Eszter K Vladar, Michael Könnecke, Birgit Hüsing, Robert Linke, Ralph Pries, Norbert Reiling, Jeffrey D Axelrod, Jayakar V Nayak, Barbara Wollenberg
The signaling pathways that sustain the disease process of chronic rhinosinusitis with nasal polyps (CRSwNP) remain poorly understood. We sought to determine the expression levels of Wnt signaling genes in CRSwNP, and to study the role of the Wnt pathway in inflammation and epithelial remodeling in the nasal mucosa. Microarrays and RT-qPCR comparing gene expression in matched nasal polyps (NP) and inferior turbinates (IT) revealed that WNT2B, WNT3A, WNT4, WNT7A, WNT7B and FZD2 were upregulated, and FZD1, LRP5, LRP6 and WIF1 downregulated in NPs...
January 6, 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28017262/correlation-between-acoustic-rhinometry-computed-rhinomanometry-and-cone-beam-computed-tomography-in-mouth-breathers-with-transverse-maxillary-deficiency
#2
Raquel Harumi Uejima Satto Sakai, Fernando Augusto Lima Marson, Emerson Taro Inoue Sakuma, José Dirceu Ribeiro, Eulália Sakano
INTRODUCTION: To provide clinical information and diagnosis in mouth breathers with transverse maxillary deficiency with posterior crossbite. Numerous exams can be performed; however, the correlation among these exams remains unclear. OBJECTIVE: To evaluate the correlation between acoustic rhinometry, computed rhinomanometry, and cone-beam computed tomography in mouth breathers with transverse maxillary deficiency. METHODS: A cross-sectional study was conducted in 30 mouth breathers with transverse maxillary deficiency (7-13 y...
November 25, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28002421/baicalin-down-regulates-il-1%C3%AE-stimulated-extracellular-matrix-production-in-nasal-fibroblasts
#3
Jae-Min Shin, Ju-Hyung Kang, Seoung-Ae Lee, Il-Ho Park, Heung-Man Lee
PURPOSE: Baicalin, a Chinese herbal medicine, has anti-fibrotic and anti-inflammatory effects. The aims of present study were to investigate the effects of baicalin on the myofibroblast differentiation, extracellular matrix production, migration, and collagen contraction of interleukin (IL)-1β-stimulated nasal fibroblasts and to determine the molecular mechanism of baicalin in nasal fibroblasts. METHODS: Nasal fibroblasts were isolated from the inferior turbinate of patients...
2016: PloS One
https://www.readbyqxmd.com/read/27983906/-b-cell-non-hodgkin-s-lymphoma-with-the-involvement-of-inferior-turbinate-a-case-report
#4
Hasan Çetiner, Erol Keleş, Gülşah Kaygusuz, Yavuz Sultan Selim Yıldırım, Duygu Kankaya
The non-Hodgkin's lymphoma is a significant malignant disease that can involve in the extranodal region of the head and neck. It does not show any specific symptoms when it resides in this region. Swelling, pain and ulceration are important clinical findings. In this article, we report a 57-year-old male patient diagnosed with B cell non-Hodgkin's lymphoma by histopathologic examination, who had nasal blockage, snoring and headache complaints for one year, whose endoscopic nasal examination revealed a mass arising from the right inferior turbinate and the mass was removed surgically by endoscopic approach...
November 2016: Kulak Burun Boğaz Ihtisas Dergisi: KBB, Journal of Ear, Nose, and Throat
https://www.readbyqxmd.com/read/27978883/-investigation-on-the-expression-of-microvessel-pericyte-coverage-index-and-lymph-vessel-density-in-nasal-polyps
#5
N Cui, D D Zhu, G M Guan, J C Sha, C D Meng, L Li, Q Xiu
Objective: To investigate the role of lymph vessel density (LVD) and microvessel pericyte coverage index (MPI) in the pathogenesis of nasal polyps. Methods: Using immunohistochemistry and immunofluorescence double staining method, the expressions of albumin, D2-40 and CD34-α-SMA in 11 specimens of normal nasal mucosa, 26 specimens of nasal polyp and 26 specimens of inferior turbinate tissue from patients with nasal polyps were investigated. The counts of microvessel density (MVD), lymph vessel density (LVD) and microvessel pericyte coverage index (MPI) were compared...
December 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/27978529/effect-of-temporal-fascia-and-pedicle-inferior-turbinate-mucosal-flap-on-repair-of-large-nasal-septal-perforation-via-endoscopic-surgery
#6
Ming Xu, Yong He, Xia Bai
BACKGROUND: The repair of large nasal septal perforations (NSPs) is one of the most challenging procedures in nasal surgery. The aim of this prospective clinical study was to determine the efficacy of using a pedicle inferior turbinate mucosal flap combined with temporal fascia to repair a large NSP. METHOD: Between January 2008 and December 2015, 17 consecutive patients with large NSPs underwent septal perforation repair via an endoscopic approach using a pedicle inferior turbinate mucosal flap combined with temporal fascia...
December 16, 2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27941731/structural-variations-of-nose-and-paranasal-sinuses-in-various-sinonasal-pathologies-tomographic-study-of-50-cases-in-bangladeshi-people
#7
M A Litu, M R Bhuiyan, S Mahmud, M K Masud, M A Khan, M A Rahman, F Ferdouse, M S Arafat
The aim of this study was to determine the frequency of structural variations in nose & paranasal sinuses in computed tomography in Bangladeshi people. This retrospective study was done at the Sir Salimullah Medical College Mitford Hospital and Apollo Hospitals, Dhaka, Bangladesh. Fifty (50) CT scan of Nose and Para nasal sinuses were collected from the patients presented with different sinonasal pathologies in OPD, IPD of both hospitals from July 2013 to June 2014. The scans were reviewed for the presence of different structural variations of nose and paranasal sinuses...
October 2016: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/27938613/-extracranial-meningiomas-from-inferior-turbinate-a-case-report
#8
J Y Wang, X D Wei, L Li, J He, F L Liu, C Huang
No abstract text is available yet for this article.
November 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/27922925/update-on-nonmalignant-lesions-of-the-inferior-turbinate
#9
Jared M Goldfarb, David Goldfarb, Marc R Rosen
PURPOSE OF REVIEW: The inferior turbinates are routinely examined by otolaryngologists on anterior rhinoscopy and nasal endoscopy. Most lesions of the inferior turbinate are benign but can often be confused with malignancy. This review highlights the broad differential of nonmalignant lesions of the inferior turbinates and their management. RECENT FINDINGS: A variety of infectious, inflammatory, neoplastic, and vascular lesions may affect the inferior turbinates...
February 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/27918749/correlation-of-nasal-mucosal-temperature-with-subjective-nasal-patency-in-healthy-individuals
#10
Ryan S Bailey, Kevin P Casey, Sachin S Pawar, Guilherme J M Garcia
Importance: Historically, otolaryngologists have focused on nasal resistance to airflow and minimum airspace cross-sectional area as objective measures of nasal obstruction using methods such as rhinomanometry and acoustic rhinometry. However, subjective sensation of nasal patency may be more associated with activation of cold receptors by inspired air than with respiratory effort. Objective: To investigate whether subjective nasal patency correlates with nasal mucosal temperature in healthy individuals...
December 1, 2016: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/27888644/myrtol-standardized-affects-mucociliary-clearance
#11
Ying Ying Li, Jing Liu, Chun Wei Li, Somasundaram Subramaniam, Siew Shuen Chao, Feng Gang Yu, Noam A Cohen, Shi Li, Yun Wang
BACKGROUND: Myrtol standardized (Gelomyrtol forte) has been shown to be effective in controlling nasal symptoms of rhinosinusitis by promoting mucociliary clearance. Our aim was to evaluate the short- and long-term effects of myrtol on ciliated columnar cells and goblet cells in an in-vitro setting. METHODS: Nasal epithelial cells were harvested (42 days) from an air-liquid interface (ALI) culture of human nasal epithelial stem/progenitor cells (hNESPCs), which was derived from biopsies of nasal inferior turbinate mucosa...
November 26, 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/27876739/-the-state-of-the-nasal-mucosa-and-the-paranasal-sinuses-in-the-late-postoperative-period-following-radical-and-minimally-invasive-surgery
#12
M M Magomedov, D F Zeinalova, D V Andriyashkin, N M Magomedova, A E Starostina, M V Zvereva
We have investigated the functional state of the mucous membrane of the nasal cavity and maxillary sinus after radical and minimally invasive surgical procedures during the log-term postoperative period, i.e. three and more months after the intervention. The materials for the study were brushings and histological biopsies; in addition, the functional parameters of the mucous membranes of the nose and maxillary sinuses were estimated before and after surgery. It has been found that the type of the surgical intervention on the inferior turbinate bones for the treatment of chronic rhinitis, such as gentle turbinotomy, has no significant influence on the state of the mucous membrane...
2016: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/27861945/rapid-hemostasis-in-a-sheep-model-using-particles-that-propel-thrombin-and-tranexamic-acid
#13
James R Baylis, Andres Finkelstein-Kulka, Luis Macias-Valle, Jamil Manji, Michael Lee, Elina Levchenko, Christopher Okpaleke, Salahuddin Al-Salihi, Amin Javer, Christian J Kastrup
OBJECTIVES/HYPOTHESIS: Bleeding during endoscopic sinus surgery and open surgeries can easily obstruct the surgeons' field of view and increase morbidity and risk of intraoperative complications. Intraoperative bleeding could potentially be addressed by a hemostatic agent that safely disperses itself through the escaping blood. We tested the safety and efficacy of a self-propelling formulation of thrombin and tranexamic acid (SPTT) in stopping bleeding in a paranasal sinus injury and in an open surgical carotid injury sheep model...
November 10, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27857872/the-lamb-s-head-as-a-model-for-surgical-skills-development-in-endonasal-surgery
#14
Luíza Baptista Mallmann, Otávio Bejzman Piltcher, Gustavo Rassier Isolan
Objectives To test the viability of a lamb's head model for sinonasal surgery training in Brazil by comparing performance of endoscopic procedures in the septum and inferior turbinates. Design Prospective study. Settings Universidade Federal do Rio Grande do Sul (2015). Participants Ten physicians performed septoplasty, inferior turbinoplasty, and middle turbinectomy on 30 lamb's heads. Main Outcome Measures Degree of difficulty and similarity, opinion of tissue color and texture, and degree of satisfaction...
December 2016: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/27844224/minimally-invasive-medial-maxillectomy-and-the-position-of-nasolacrimal-duct-the-ct-study
#15
Andrzej Sieskiewicz, Krzysztof Buczko, Jacek Janica, Adam Lukasiewicz, Urszula Lebkowska, Bartosz Piszczatowski, Ewa Olszewska
Several minimally invasive modifications of endoscopic medial maxillectomy have been proposed recently, with the least traumatic techniques utilizing the lacrimal recess as a route to enter the sinus. The aim of the study was to analyze the anatomy of medial maxillary wall in the region of nasolacrimal canal and, thus, to determine the capability of performing minimally invasive approach to the maxillary sinus leading through the lacrimal recess. The course of nasolacrimal canal and the distance between the anterior maxillary wall and the nasolacrimal canal (the width of lacrimal recess) were evaluated in 125 randomly selected computed tomography (CT) head examinations...
November 14, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27833866/long-term-outcomes-of-radiofrequency-ablation-of-the-inferior-turbinates
#16
Casey Means, Macario Camacho, Robson Capasso
Radiofrequency ablation of the inferior turbinates (RFAIT) is a minimally invasive surgical technique that reduces turbinate size and decreases nasal obstruction. Few studies have assessed long-term outcomes of this procedure using standardized, symptom-specific evaluation instruments. The primary aim of this study is to assess the long-term effectiveness of RFAIT using a standardized, symptom-specific evaluation instrument. An additional outcome evaluated is the effect of RFAIT on therapeutic CPAP pressures in centimetres of water pressure (cwp) and overall CPAP use...
December 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/27831517/nasal-and-tracheal-cytological-changes-after-total-laryngectomy-in-long-term-survivors
#17
Giuseppe Riva, Monica Boita, Andrea Corvino, Matteo Sensini, Daniela Peruzzetto, Luigi Chiusa, Giancarlo Pecorari, Massimiliano Garzaro
OBJECTIVE: Complete separation of upper and lower respiratory tract after total laryngectomy results in permanent effects on nasal cavities and tracheo-bronchial airways. Aim of this study is evaluating nasal and tracheal cytological alterations of mucosa in laryngectomy long-term survivors, analyzing the feasibility of scraping for cytological examination of tracheal mucosa. METHODS: Twenty-five laryngectomy patients underwent symptoms' evaluation, endoscopic fiber optic examination, prick tests, and nasal and tracheal scraping for cytological exam...
November 9, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/27807867/increase-of-poorly-proliferated-p63-ki67-basal-cells-forming-multiple-layers-in-the-aberrant-remodeled-epithelium-in-nasal-polyps
#18
Li Zhao, Ying Ying Li, Chun Wei Li, Siew Shuen Chao, Jing Liu, Ha Nguyen Nam, Dung Nguyen Thi Ngoc, Li Shi, De Yun Wang
BACKGROUND: Aberrant epithelial remodeling with the ectopic expression of p63 (basal cell markers) is an important pathologic phenomenon seen in chronically inflamed airway epithelium such as in nasal polyps (NPs). METHODS: Biopsies were obtained from 55 NP patients and 18 healthy controls (inferior turbinate). Among NP patients, fifteen were treated with oral and nasal steroids, so that two sets of NPs biopsies were taken before and after the treatments. p63, Ki67, type IV β-tubulin and cell-cycle markers were investigated in these specimens...
November 2, 2016: Allergy
https://www.readbyqxmd.com/read/27801958/nasal-obstructive-disorders-induce-medical-treatment-failure-in-paediatric-persistent-allergic-rhinitis-the-nodpar-study
#19
Franklin S Mariño-Sánchez, Meritxell Valls-Mateus, Karen Ruiz-Echevarría, Isam Alobid, Paulina Cardenas-Escalante, Rosa Jiménez-Feijoo, Jaime Lozano-Blasco, María T Giner-Muñoz, Jesús Rodríguez-Jorge, Oliver Haag, Ana M Plaza-Martin, Joaquim Mullol
BACKGROUND: Allergic rhinitis (AR) is the most common chronic disease among children. To characterize the disease, a modified classification of severity (m-ARIA) has recently been validated in AR children. When medical treatment fails, surgery for nasal obstructive disorders (NOD) may be a therapeutic option. Our objective was to assess the prevalence of NOD and their influence in medical treatment response among children with persistent AR (PER). METHODS: In a prospective, real-life study, 130 paediatric PER patients (13...
November 1, 2016: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/27746257/surgical-site-infections-following-bimaxillary-orthognathic-osseous-genioplasty-and-intranasal-surgery-a%C3%A2-retrospective-cohort-study
#20
Jeffrey C Posnick, Elbert Choi, Anish Chavda
PURPOSE: Frequency estimates of surgical site infection (SSI) after orthognathic surgery vary considerably. The purpose of this study was to determine the incidence and site of SSIs and associated risk factors after bimaxillary orthognathic, osseous genioplasty, and intranasal surgery. MATERIALS AND METHODS: The authors executed a retrospective cohort study of patients with a bimaxillary developmental dentofacial deformity (DFD) and symptomatic chronic obstructive nasal breathing...
September 20, 2016: Journal of Oral and Maxillofacial Surgery
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