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Inferior turbinate

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https://www.readbyqxmd.com/read/28809842/noninvasive-sampling-of-mucosal-lining-fluid-for-the-quantification-of-in-vivo-upper-airway-immune-mediator-levels
#1
Helene M Wolsk, Bo L Chawes, Jonathan Thorsen, Jakob Stokholm, Klaus Bønnelykke, Susanne Brix, Hans Bisgaard
This protocol describes noninvasive sampling of undisturbed upper airway mucosal lining fluid. It also details the extraction procedure used prior to the analysis of immune mediators in fluid eluates for the study of the airway topical immune signature, without the need for stimulation procedures (often used by other techniques). The mucosal lining fluid is sampled on a strip of filter paper placed at the anterior part of the inferior turbinate and left for 2 min of absorption. Analytes are eluted from the filter papers, and the extracted protein-based eluates are analyzed by an electrochemiluminescence-based immunoassay, allowing for the high-sensitivity quantification of low- and high-level analytes in the same sample...
August 7, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28804222/chemical-chaperone-of-endoplasmic-reticulum-stress-inhibits-epithelial-mesenchymal-transition-induced-by-tgf-%C3%AE-1-in-airway-epithelium-via-the-c-src-pathway
#2
Heung-Man Lee, Ju-Hyung Kang, Jae-Min Shin, Seoung-Ae Lee, Il-Ho Park
Epithelial-mesenchymal transition (EMT) is a biological process that allows epithelial cells to assume a mesenchymal cell phenotype. EMT is considered as a therapeutic target for several persistent inflammatory airway diseases related to tissue remodeling. Herein, we investigated the role of endoplasmic reticulum (ER) stress and c-Src in TGF-β1-induced EMT. A549 cells, primary nasal epithelial cells (PNECs), and inferior nasal turbinate organ cultures were exposed to 4-phenylbutylic acid (4PBA) or PP2 and then stimulated with TGF-β1...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28711215/changes-occurring-in-mucosal-contractility-of-the-inferior-turbinate-and-mucociliary-clearance-following-total-laryngectomy-a-prospective-clinical-trial
#3
Ilker Kocak, Remzi Dogan, Sabri Baki Eren, Selahattin Tugrul, Orhan Ozturan, Aysenur Meric Hafiz
OBJECTIVE: In this study, changes occurring in the contractility capacity of the inferior turbinate and mucociliary clearance time due to the interruption of nasal air flow were examined. MATERIAL & METHODS: A total of 23 patients undergone total laryngectomy between June 2010 and June 2012 were included in the study. Acoustic rhinometry test was performed in the patients before and after 0.05% oxymetazoline nasal topical decongestant administration. In addition, saccharin test was applied in order to measure mucociliary clearance...
July 12, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28702184/maxillary-artery-based-flaps-for-oral-cavity-reconstruction-a-review
#4
REVIEW
Amin Rahpeyma, Saeedeh Khajehahmadi
BACKGROUND: There are different flaps based on the branches of the maxillary artery. Flaps based on the maxillary artery branches can be used for oral cavity reconstruction in selected cases, but there is lack of comprehensive review in this topic. METHODS: A literature review was performed on Medline for maxillary artery based flaps and oral cavity reconstruction. Surgical techniques for each possible variant of maxillary artery based flaps and an example of each situation for oral cavity reconstruction is explained...
August 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28700811/probing-for-congenital-nasolacrimal-duct-obstruction
#5
REVIEW
Carisa Petris, Don Liu
BACKGROUND: Congenital nasolacrimal duct obstruction (NLDO) is a common condition causing excessive tearing in the first year of life. Infants present with excessive tearing or mucoid discharge from the eyes due to blockage of the nasolacrimal duct system, which can result in maceration of the skin of the eyelids and local infections, such as conjunctivitis, that may require antibiotics. The incidence of nasolacrimal duct obstruction in early childhood ranges from 5% to 20% and often resolves without surgery...
July 12, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28680498/impact-of-successful-choanal-atresia-repair-on-the-nasal-mucosa-a-preliminary-study
#6
Ezzeddin Elsheikh, Mohammad Waheed El-Anwar, Hesham Radwan Abdel-Aziz
Introduction  The main histological features of the nasal mucosa in choanal atresia are distorted cilia, marked increase of mucous submucosal glands associated with marked reduction of goblet cell density, and lymphocytic cellular infiltration. Objective  To study the nasal mucosal changes in cases of choanal atresia after successful repair compared with pre-repair mucosal histological features. Methods  Tissue samples were taken from the inferior turbinate of 3 patients (1 bilateral and 2 unilateral) who were successfully operated...
July 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28676318/postoperative-alar-base-symmetry-in-complete-unilateral-cleft-lip-and-palate-a-prospective-study
#7
Suresh Vyloppilli, K S Krishnakumar, Shermil Sayd, Sameer Latheef, Saju V Narayanan, Ajit Pati
In the evolution of cleft lip repair, there have been continuous attempts to minimize local trauma and to improve lip and nasal appearances. In order to obtain an aesthetically balanced development of midface, the primary surgical correction of the nasolabial area is of paramount importance. In this study, the importance of a back-cut extending cephalically above the inferior turbinate at the mucocutaneous junction which elevates the nostril floor on the cleft side for the purpose of achieving symmetry of the alar bases are analyzed by pre and postoperative photographic anthropometry...
June 9, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28669540/successful-management-of-primary-atrophic-rhinitis-by-turbinate-reconstruction-using-autologous-costal-cartilage
#8
Marn Joon Park, Yong Ju Jang
Initial management of primary atrophic rhinitis is conservative, with nasal ointments, saline irrigation, and antibiotics prescribed to relieve symptoms. However, in cases that show no improvement, a surgical approach is considered. Recently, many studies have reported successful surgical outcomes using various nasal implants. However, no study has reported implantation of autologous costal cartilage in PAR patients. We report here the case of a 63-year-old woman diagnosed with PAR that was intractable to medical therapy...
June 29, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28669486/method-of-osteotomy-fixation-and-need-for-removal-following-bimaxillary-orthognathic-osseous-genioplasty-and-intranasal-surgery-a-retrospective-cohort-study
#9
J C Posnick, E Choi, A Chavda
The purpose of this study was to determine the incidence and causes of fixation hardware removal after bimaxillary orthognathic, osseous genioplasty, and intranasal surgery. A retrospective study was performed, involving subjects with a bimaxillary developmental dentofacial deformity (DFD) and symptomatic chronic obstructive nasal breathing. At a minimum, subjects underwent Le Fort I osteotomy, bilateral sagittal ramus osteotomies (SROs), septoplasty, inferior turbinate reduction, and osseous genioplasty. The primary outcome variable studied was fixation hardware removal...
June 29, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28663599/palate-perforation-differentiates-cocaine-induced-midline-destructive-lesions-from-granulomatosis-with-polyangiitis
#10
M Trimarchi, S Bondi, E Della Torre, M R Terreni, M Bussi
Cocaine abuse occasionally causes extensive destruction of the osteocartilaginous structures of the nose, sinuses and palate, which mimics the clinical picture of other diseases associated with necrotising midfacial lesions. The differentiation of cocaine-induced midline destructive lesions (CIMDL) and limited granulomatosis with polyangiitis (GPA) may be difficult, particularly if patients do not readily admit substance abuse. We studied 10 patients with CIMDL and palate perforation referred to our Unit between 2002 and 2015...
June 30, 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28658818/a-prospective-study-of-different-methods-of-inferior-turbinate-reduction
#11
Santosh Uttarkar Panduranga Rao, Prashanth Basavaraj, Supriya Basavaraj Yempalle, Aravind Darga Ramachandra
INTRODUCTION: All the functions of nasal cavities are performed through mucosa and contours of the turbinates. Hypertrophied inferior turbinate is one of the major and common causes of nasal obstruction. In these patients nasal obstruction is relieved by inferior turbinate reduction. Many procedures on turbinate reduction have been described earlier. AIM: To compare and evaluate the better method for inferior turbinate reduction among submucosal diathermy using monopolar cautery and bipolar cautery, complete turbinectomy, inj...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28657531/-analysis-of-nasal-cytology-in-children-and-adolescents-with-rhinitis
#12
Natalia A Lozano, Ricardo J Saranz, Alejandro Lozano, María Del Pilar Bovina Martijena, Maximiliano Ramirez, Marina F Ponzio, Yanina V Berardi, Ana G Sosa, Eugenia Cóncari
BACKGROUND: Nasal cytology in a easy-to apply method to differentiate rhinitis phenotypes from a physiopathogenic and diagnostic perspective. There are controversies about the relationship between clinical severity of rhinitis and inflammatory patterns expressed in the nasal cytology. OBJECTIVES: To study the characteristic of the eosinophil and neutrophil patterns in the nasal scraping for Allergic Rhinitis (AR) and Non Allergic Rhinitis (NAR) and its relationship with the clinical grades of rhinitis established by the Allergic Rhinitis and its Impact on Asthama Guideline (ARIA) Methods: In a observational, cross-sectional study we included patients aged 5 to 18 years presenting symptoms of either allergic (AR) or non- allergic rinitis (NAR) without asthma...
2017: Revista de la Facultad de Ciencias Médicas
https://www.readbyqxmd.com/read/28636737/is-there-an-association-between-migraine-and-allergic-rhinitis
#13
Işıl Adadan Güvenç, Mustafa Acar, Nuray Bayar Muluk, Nagehan Erdogmus Kucukcan, Cemal Cingi
We conducted a prospective study to evaluate nasal signs and symptoms and to perform allergen-specific immunoglobulin E (IgE) testing to investigate the relationship between migraine and allergic rhinitis. Our study group consisted of 40 patients diagnosed with migraine-22 men and 18 women, aged 21 to 38 years (mean: 25.7). We compared their findings with a control group of 40 healthy adults-15 men and 25 women, aged 19 to 36 years (mean: 25.1). Allergen-specific IgE measurements were obtained with six groups of allergens: fungi, grass pollens, tree pollens, wild herbs, house dust mite 1, and house dust mite 2...
June 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28631677/-topographical-and-anatomical-localization-of-the-lacrimal-passages-in-the-nasal-cavity
#14
M M Magomedov, D V Andriayshkin, M N Magomedova, D F Zeinalova
The objective of the present work was to study topographical and anatomical relationships between the lacrimal passages and the walls of the nasal cavity from the standpoint of the rhinosurgeon. The materials for the study were obtained by examining 15 corpses. It was found out that in 91% of the cases, the natural ostium of the maxillary sinus is localized within 11.6 cm from the lacrimal tubercle. In 62% of the cases, the nasolacrimal passage opens in the region of the vault of the inferior nasal passage as an orifice roughly 0...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28623043/nasal-airway-evaluation-in-obstructive-sleep-apnoea-patients-volumetric-tomography-and-endoscopic-findings
#15
M M Rodrigues, M F R Gabrielli, O A Garcia Junior, V A Pereira Filho, L A Passeri
Obstructive sleep apnoea (OSA) results from the recurrent collapse of the upper airway during sleep. Nasal abnormalities influence the stability of the pharynx. The aim of this study was to evaluate the volumetric and anatomical changes of the nasal cavity in patients with OSA. The Nasal Obstruction Symptom Evaluation (NOSE) scale was used to grade nasal obstruction. Sleep-related breathing disorders were evaluated by polysomnography. The nasal airway volume was obtained from computed tomography scans through volumetric reconstruction of the nasal airway...
June 13, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28615628/glucocorticoids-ameliorate-tgf-%C3%AE-1-mediated-epithelial-to-mesenchymal-transition-of-airway-epithelium-through-mapk-and-snail-slug-signaling-pathways
#16
Hyun-Woo Yang, Seoung-Ae Lee, Jae-Min Shin, Il-Ho Park, Heung-Man Lee
Chronic rhinosinusitis with nasal polyps (CRSwNP) is closely associated with tissue remodeling. Epithelial-to-mesenchymal transition (EMT), a process of tissue remodeling, can be a therapeutic target of CRSwNP. Glucocorticoids are a type of steroid hormone that is used primarily in medical therapy for patients with CRSwNP; however, their effects on EMT in the airway epithelium remain unknown. To investigate the effects of dexamethasone and fluticasone propionate, a class of glucocorticoids, on transforming growth factor-β1 (TGF-β1) -induced EMT, we used A549 cells, human primary nasal epithelial cells (hPNECs) and ex vivo organ culture of the inferior turbinate...
June 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28608764/radioanatomic-study-of-the-greater-palatine-canal-relevant-to-endoscopic-endonasal-surgical-landmarks
#17
Noel Ayoub, Andrew Thamboo, Peter H Hwang, Evan S Walgama
Objective A radioanatomic study of surgically relevant variations in the greater palatine canal (GPC) on computed tomography (CT) was performed to determine susceptibility during endoscopic endonasal procedures. Study Design Blinded radioanatomic analysis. Setting Tertiary university hospital. Subjects and Methods Fifty consecutive paranasal CT scans (100 sides) were analyzed. Measurements were standardized to landmarks such as the inferior turbinate (IT) and floor of the nasal cavity (FNC) to assess variability and vulnerability of the nerve...
June 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28602068/radiographic-changes-of-the-nasal-septal-body-among-patients-with-sinonasal-diseases
#18
January E Gelera, Devendra Ojar, Jae Hyun Lim, Jee Hye Wee, Jeong-Whun Kim, Chae-Seo Rhee
Objectives: This study aims to determine the anatomical changes occurring in the nasal septal body (NSB) among patients with sinonasal disease and compares the measurements obtained from patients without sinonasal disease. Methods: This was a retrospective study involving review of 405 (93 without and 212 with sinonasal disease) plain paranasal sinus computed tomography (PNS CT) on coronal view at a tertiary training hospital, which was done consecutively from January 2014 to December 2015...
June 6, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28583512/comprehensive-management-of-congenital-choanal-atresia
#19
Pierre Brihaye, Isabelle Delpierre, Andrée De Villé, Anne-Britt Johansson, Dominique Biarent, Anne-Laure Mansbach
OBJECTIVES: To present results of a one-stage minimally invasive surgical procedure for congenital choanal atresia (CCA). Seven outcome measures were applied. MATERIALS AND METHODS: Retrospective study conducted between 1999 and 2015. The same endonasal endoscopic approach with multiflaps and no stenting was used on 36 children. The flaps were attached with fibrine glue. There were 50% unilateral and 50% bilateral cases, 70% primary and 30% secondary surgery. The mean age at primary surgery for bilateral atresia was 10 days and for unilateral atresia 4 years...
July 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28571175/unilateral-absence-of-ethmoid-sinus-and-nasal-turbinates-a-rare-case-report
#20
Vinod Felix, Narendrakumar Veerasigamani
A variety of anatomical variation of paranasal sinus and nasal turbinates exist, as its development is a complex and long standing process. Computerized Tomography (CT) of the paranasal sinuses is a very valuable tool in diagnosing these variations. Preoperatively defining the anatomical variations of the intranasal structures is essential in performing the safe functional endoscopic sinus surgery and to avoid unnecessary complications. Several degrees and combinations of aplasias and hypoplasias have been reported...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
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