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Metastasectomy

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https://www.readbyqxmd.com/read/29147667/metastasectomy-of-solitary-adrenal-metastasis-from-small-cell-lung-cancer
#1
Dat Cao Pham, Ziad Awad, Bradford S Hoppe, Jason Hew, Ke Ning
Most extensive-stage small cell lung cancers have disseminated disease at diagnosis, and solitary adrenal metastasis from small cell lung cancer is rare. We report the case of a 51-year-old man with extensive-stage small cell lung cancer with solitary right adrenal metastasis (T2N0M1), who was cured with resection of primary tumor, chemotherapy (cisplatin, etoposide), adrenalectomy, consolidative thoracic radiotherapy, and prophylactic cranial irradiation. He remained cancer free, 7.5 years since diagnosis...
October 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/29137284/treatment-strategy-and-prognostic-factors-for-krukenberg-tumors-of-gastric-origin-report-of-a-10-year-single-center-experience-from-china
#2
Pengfei Yu, Ling Huang, Guoping Cheng, Litao Yang, Gaiguo Dai, Jieer Ying, Yian Du
Background: Gastric cancer patient with ovarian metastasis is common in clinical practice, but it is still uncertain whether surgical resection of ovarian metastasis could improve the outcome. This study aimed to explore the survival benefit of metastasectomy plus chemotherapy over chemotherapy alone in the treatment of Krukenberg tumors arising from gastric cancer and to identify prognostic factors. Results: A total of 152 patients were identified, including 93 patients with synchronous ovarian metastasis and 59 patients with metachronous ovarian metastasis...
October 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29135665/cryoablation-of-bone-metastases-from-renal-cell-carcinoma-for-local-tumor-control
#3
Carly S Gardner, Joe E Ensor, Kamran Ahrar, Steven Y Huang, Sharjeel H Sabir, Nizar M Tannir, Valerae O Lewis, Alda L Tam
BACKGROUND: Patients with bone metastases from renal cell carcinoma often are not surgical candidates and have a poor prognosis. There are limited data on the use of cryoablation as a locoregional therapy for bone metastases. Our objective was to assess the local tumor-control rate following cryoablation of bone metastases in the setting of renal cell carcinoma. METHODS: We retrospectively reviewed the medical records of patients with metastatic renal cell carcinoma who underwent cryoablation for bone metastases between 2007 and 2014...
November 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29119020/pulmonary-metastasectomy-in-uterine-malignancy-outcomes-and-prognostic-factors
#4
REVIEW
Rocco Bilancia, Marco Nardini, David Waller
Metastatic uterine cancer is a form of systemic disease. As for other solid tumours, it is advocated by some authors that in selected patients, lung metastasectomy may play a role in long-term disease control. The practice of lung metastasectomy is however open to criticism as there is lack of convincing evidence, and over-encouraging outcomes may be attributed to intrinsic selection bias. The case of metastatic uterine tumours is reviewed in the light of the available literature, in order to identify common patterns and prognostic factors that may influence and determine an individualised and informed patient decision...
October 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29119019/survival-and-prognostic-factors-following-pulmonary-metastasectomy-for-sarcoma
#5
REVIEW
Giuseppe Marulli, Marco Mammana, Giovanni Comacchio, Federico Rea
Sarcomas are a heterogeneous group of malignancies with a marked propensity to metastasize to the lungs. Chemotherapy offers only a limited benefit in metastatic disease, whereas lung metastasectomy, in selected cases, can lead to long-term survival. Other local ablative techniques and hybrid therapies have been proposed. A multidisciplinary setting is of paramount importance for choosing the most appropriate treatment for each case. There is no randomized controlled trial providing formal evidence of the effectiveness of lung metastasectomy...
October 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29119018/metastasectomy-in-pediatric-patients-indications-technical-tips-and-outcomes
#6
REVIEW
Paolo Scanagatta, Lara Girelli
Pulmonary metastasectomy has become a standard procedure for pediatric patients with certain types of solid tumors. Surgeons, expert pediatric oncologists and radiation oncologists contribute with their different skills to the management of pulmonary metastases. Patients are usually scheduled for surgery in case of primary tumor control, in absence of metastases in other organs and when a complete resection is achievable. Nodules are removed through precision resections using electrocautery or laser methods in order to ensure radical surgery with adequate margins...
October 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29119017/pulmonary-metastasectomy-an-overview
#7
REVIEW
Francesco Petrella, Cristina Diotti, Arianna Rimessi, Lorenzo Spaggiari
Metastasectomy is the most frequent surgical resection undertaken by thoracic surgeons, being the lung the second common site of metastases. The present oncological criteria for pulmonary metastasectomy are: (I) the primary cancer need to be controlled or controllable; (II) no extrathoracic metastasis-that is not controlled or controllable-exists; (III) all of the tumor must be resectable, with adequate pulmonary reserve; (IV) there are no alternative medical treatment options with lower morbidity. General favourable prognostic features in patients with pulmonary metastases are: (I) one or few metastases; (II) long disease free interval; (III) normal CEA levels in colorectal cancers...
October 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29119016/pulmonary-metastasectomy-for-colorectal-cancer-analysis-of-prognostic-factors-affecting-survival
#8
Luca Ampollini, Letizia Gnetti, Matteo Goldoni, Lorenzo Viani, Elisabetta Faedda, Nicoletta Campanini, Pietro Caruana, Pellegrino Crafa, Francesca Negri, Francesca Pucci, Francesco Leonardi, Luigi Ventura, Valeria Balestra, Cesare Braggio, Giovanni Bocchialini, Paolo Del Rio, Enrico Maria Silini, Paolo Carbognani, Michele Rusca
Background: Pulmonary metastasectomy is considered a standard procedure in the treatment of metastatic colorectal cancer (CRC). Different prognostic factors including multiple metastatic nodules, the presence of extra-pulmonary metastases and BRAF mutation status have been associated with poor survival. The aim of this study was to evaluate which factors influenced survival in CRC patients undergoing pulmonary metastasectomy by studying primary tumors and pulmonary metastases. Methods: All patients treated for primary CRC who presented pulmonary metastases in a 10-year period were considered (group A)...
October 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29119015/pulmonary-metastasectomy-for-sarcoma-essen-experience
#9
Dumitrita Alina Gafencu, Stefan Welter, Danjouma Housmanou Cheufou, Till Ploenes, Georgios Stamatis, Martin Stuschke, Dirk Theegarten, Christian Taube, Sebastian Bauer, Clemens Aigner
Background: Pulmonary metastasectomy is an established treatment modality for patients with soft as well as bone tissue sarcomas. Aim of this study is to describe the Essen experience in the surgical management of patients with pulmonary sarcoma metastases. Methods: This is a retrospective single center analysis of perioperative outcome of patients undergoing pulmonary metastasectomy for sarcoma metastases from 1997-2017 and a summary of published papers on this topic...
October 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29119014/pulmonary-metastasectomy-in-uterine-malignancies-outcome-and-prognostic-factors
#10
Marco Anile, Sara Mantovani, Ylenia Pecoraro, Carolina Carillo, Lorenzo Gherzi, Andreina Pagini, Erino Angelo Rendina, Federico Venuta, Daniele Diso
Background: This retrospective study is designed to evaluate factors affecting survival in a population of patients receiving pulmonary metastasectomy after gynecologic cancers. Methods: Nineteen patients with isolated lung metastases (one or two) were surgically treated with R0 resection. Four of them underwent lobectomies. Results: Six patients (31.6%) received adjuvant therapy and 11 (58%) experienced recurrences after metastasectomy. Five- and ten-year survival were 40...
October 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29119013/lung-metastasectomy-following-kidney-tumors-outcomes-and-prognostic-factors-from-a-single-center-experience
#11
Elisa Meacci, Dania Nachira, Maria Teresa Congedo, Venanzio Porziella, Marco Chiappetta, Gianmaria Ferretti, Amedeo Iaffaldano, Leonardo Petracca Ciavarella, Stefano Margaritora
Background: The lung is one of the sites most frequently affected by metastatic renal cell carcinoma (mRCC). Nonsurgical therapy for mRCC has limited efficacy, while the 5-year survival rates data published in literature after pulmonary surgery for metastasectomy, emphasize the role of surgery as the treatment that guarantees the best effectiveness in pulmonary resectable metastases. Methods: From January 2000 to March 2016, 27 patients underwent pulmonary metastasectomy for metastatic renal cancer was retrospectively reviewed...
October 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29119012/prognostic-factors-after-pulmonary-metastasectomy-of-colorectal-cancers-a-single-center-experience
#12
Ludovic Fournel, Stefania Maria, Marie Seminel, Jessica Nesci, Audrey Mansuet-Lupo, Claude Guinet, Pierre Magdeleinat, Antonio Bobbio, Jean-Fran├žois Regnard, Marco Alifano
Background: Surgical resection has been widely admitted as the treatment of choice for pulmonary metastases of colorectal cancer (CRC). Nevertheless, this practice is not supported by high level of evidence and patients' eligibility remains controversial. Aim of this study was to evaluate long terms results and factors influencing survival after lung metastasectomy of CRC. Methods: A single-center retrospective analysis of patients with pathologically proven colorectal metastasis, operated from 2004 to 2013, was performed...
October 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29119011/pulmonary-metastasectomy-beyond-the-tip-of-the-iceberg
#13
Francesco Petrella, Lorenzo Spaggiari
No abstract text is available yet for this article.
October 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29115903/5-year-survival-after-splenectomy-in-a-patient-with-recurrent-cutaneous-melanoma-a-case-report
#14
Lynn De Roeck, Laura Wuyts, Benjamin Peters, Martin Ruppert
OBJECTIVE: Splenic metastases of melanoma are uncommon and generally part of a disseminated disease with a poor prognosis. In case of solitary visceral metastasis, surgical resection often remains an effective treatment. This case describes a long-term survival after splenectomy for a recurrent melanoma. METHODS: We present a 55-year-old female with a solitary splenic metastasis. Her medical history revealed a melanoma of the foot in 2007 and an in-transit metastasis in 2011...
November 8, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/29111365/autologous-fat-tissue-grafting-improves-pulmonary-healing-after-laser-metastasectomy
#15
Simone Furia, Pierfrancesco Cadenelli, Francesca Andriani, Paolo Scanagatta, Leonardo Duranti, Andrea Spano, Carlotta Galeone, Luca Porcu, Ugo Pastorino
BACKGROUND: Extensive clinical experience has demonstrated the potential usefulness of autologous fat tissue (AFT) graft in tissue reconstruction, repair or regeneration. In the present study, we evaluated the feasibility and safety of AFT in the repair of surgically injured lung surface. METHODS: Eighty consecutive procedures of pulmonary metastasectomy by laser precision resection, were performed in 66 patients between March 2010 and December 2012. In the first 20 procedures, AFT graft was applied on the wounded pulmonary surface without closure of parenchymal surface...
October 16, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29108268/inherent-characteristics-of-metachronous-metastatic-renal-cell-carcinoma-in-the-era-of-targeted-agents
#16
Jang Hee Han, Seung Hwan Lee, Won Sik Ham, Woong Kyu Han, Koon Ho Rha, Young Deuk Choi, Sung Joon Hong, Young Eun Yoon
Background: To assess the prognostic and predictive factors of time to treatment failure (TTF) and overall survival (OS), respectively, in patients with metachronous metastatic renal cell carcinoma (mRCC) who were treated with targeted agents. Materials and Methods: We retrospectively reviewed metachronous mRCC patients, defined as individuals diagnosed with metastatic disease >3 months after initial nephrectomy, treated at an institute since 2005. Cox proportional hazard regression analysis was performed to discover the most determinant variables associated with TTF and OS...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29092022/pulmonary-metastasectomy-for-thyroid-cancer-as-salvage-therapy-for-radioactive-iodine-refractory-metastases
#17
Isabelle Moneke, Jussuf T Kaifi, Raphael Kloeser, Patrick Samson, Benedikt Haager, Sebastian Wiesemann, Sven Diederichs, Bernward Passlick
OBJECTIVES: Distant metastasis arising from thyroid cancer is rare but has been associated with significantly reduced long-term survival, especially when refractory to radioactive iodine ablation. We provide one of the largest studies worldwide reporting the outcome after salvage pulmonary metastasectomy for this entity, aiming to identify prognostic factors and to analyse surgical indication. METHODS: We retrospectively analysed the medical records of 43 patients who had undergone pulmonary metastasectomy for radioactive iodine-refractory thyroid cancer from 1985 to 2016...
October 30, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29078678/uniportal-non-intubated-lung-metastasectomy
#18
Tommaso Claudio Mineo, Francesco Sellitri, Eleonora Fabbi, Vincenzo Ambrogi
BACKGROUND: More than 15 years ago, we started a program of uniportal video-assisted thoracoscopies (VATS) lung metastasectomy in non-intubated local anesthesia. Hereby we present the short and long-term results of this combined surgical-anesthesiological technique. METHODS: Between 2005 and 2015, 71 patients (37 men and 34 women) with pulmonary oligometastases, at the first episode, underwent uniportal VATS metastasectomy under non-intubated anesthesia. RESULTS: Four patients (5...
2017: J Vis Surg
https://www.readbyqxmd.com/read/29078587/subxiphoid-uniportal-lobectomy
#19
Mohamed M Moneer ElSaegh, Nur Aziah Ismail, Mohamed I Mydin, Marco Nardini, Joel Dunning
Video-assisted thoracic surgery (VATS) surgery has seen an evolution from multiple ports to uniportal and finally subxiphoid uniportal recently. In traditional VATS surgery, the instruments and the thoracoscope enter the thoracic cavity through two to four operating ports on the lateral chest wall, which can cause chronic pain and chest wall numbness. However single-portal VATS surgery could potentially cause similar problems as the port is placed in between the ribs. In March 2015 Liu et al. reported a VATS bilateral pulmonary metastasectomy and right middle lobectomy via a subxiphoid uniportal technique...
2017: J Vis Surg
https://www.readbyqxmd.com/read/29076812/surgical-outcomes-in-patients-with-hepatic-synchronous-and-metachronous-colorectal-metastasis
#20
Maria Laura Cossu, Giorgio Carlo Ginesu, Claudio Francesco Feo, Alessandro Fancellu, Antonio Pinna, Isabel Vargiu, Francesca Addis, Michele Barmina, Giovanni Sotgiu, Alberto Porcu
AIM: To evaluate the impact of several clinical and pathological factors on the outcomes of surgery for hepatic colorectal cancer metastasis. METHODS: Eighty-four liver metastasectomies in 77 consecutive patients with 90 colorectal cancer hepatic metastases were performed in our institution from 2009 to 2014. Surgery was carried out in 75 cases, as two patients were not eligible for surgery. Among them 43 (Group A) were affected by synchronous, and 32 (Group B) by metachronous lesions...
October 25, 2017: Annali Italiani di Chirurgia
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