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https://www.readbyqxmd.com/read/28079531/the-effect-of-albumin-and-platelet-poor-plasma-supplemented-botulinum-a-toxin-on-bioavaliability-an-experimental-rabbit-model
#1
Serhat Sibar, Kemal Findikcioglu, Murat Zinnuroglu, Seyhan Cenetoglu
Today, botulinum toxin is commonly used for cosmetic purposes throughout the world. Despite various agents reducing the efficiency of toxin are well defined, the studies related to increasing the bioavailability are limited. The purpose of our study is to assess the effect of the preparation of toxin by diluting with platelet-poor plasma (PPP) and/or albumin instead of standard dilution (saline) on bioavailability in cosmetic-purpose botulinum toxin applications.In the study, 24 New Zealand rabbits were used...
January 10, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28078759/bufalin-a-bufanolide-steroid-from-the-parotoid-glands-of-the-chinese-toad-inhibits-l-type-ca-2-channels-and-contractility-in-rat-ventricular-myocytes
#2
Tao Song, Xi Chu, Xuan Zhang, Qiong Tao Song, Ying Zhang, Yuanyuan Zhang, Xue Han, Jianping Zhang, Li Chu
Bufalin is a bufanolide steroid compound in Chan Su. Chan Su is a traditional Chinese medicine prepared from the dried white secretion of the auricular and skin glands of toads, and has been used as an Oriental drug. However, the effect of bufalin on cardiac function and its underlying cellular mechanisms remain unclear. Here, we explore the cellular mechanisms of bufalin on myocardial protection via the whole-cell patch-clamp recording and video-based edge detection system. Exposure to bufalin resulted in a concentrated-dependent blockade of ICa-L , with the half-maximal inhibitory concentration (IC50 ) of 60 μM and the maximal inhibitory effect of 71...
January 11, 2017: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/28072813/a-case-report-on-red-ear-syndrome-with-tinnitus-successfully-treated-with-transcranial-random-noise-stimulation
#3
Peter M Kreuzer, Veronika Vielsmeier, Timm B Poeppl, Berthold Langguth
BACKGROUND: The red ear syndrome represents a rare symptom complex consisting of auricular erythema associated with painful and burning sensations. It has been described in combination with tinnitus rarely. It has been hypothesized to be etiologically related to altered trigeminal afferent input, temporomandibular disorders, and thalamic dysfunction. OBJECTIVES: The initial objective of applying transcranial random noise stimulation (tRNS) in a case of red ear syndrome in combination with tinnitus was the alleviation of the phantom sounds...
January 2017: Pain Physician
https://www.readbyqxmd.com/read/28067982/sensation-loss-after-superficial-parotidectomy-a-prospective-controlled-multicenter-trial
#4
Maria Grosheva, Sami Shabli, Gerd Fabian Volk, Barbara Sommer, Laura Ludwig, Mira Finkensieper, Claus Wittekindt, Jens Peter Klussmann, Orlando Guntinas-Lichius, Dirk Beutner
BACKGROUND: The purpose of this study was to evaluate the occurrence of hypoesthesia after superficial parotidectomy depending on preservation of posterior branch of the great auricular nerve (GAN). METHODS: This prospective, controlled, double blind, multicenter trial included 130 patients. The posterior branch was preserved in 93 patients (GAN group), and ligated in 33 patients (non-GAN group). In 4 patients, GAN status was unknown. Included patients underwent sensory testing (TouchTest) and subjective evaluation at 6, 12, and 24 months after surgery...
January 9, 2017: Head & Neck
https://www.readbyqxmd.com/read/28065228/comparison-of-the-ambu-aura-i-with-the-air-q-intubating-laryngeal-airway-as-a-conduit-for-fiberoptic-guided-tracheal-intubation-in-children-with-ear-deformity
#5
Juan Zhi, Xiao-Ming Deng, Dong Yang, Chao Wen, Wen-Li Xu, Lei Wang, Jin Xu
Objective To compare the Ambu Aura-i with the Air-Q intubating laryngeal airway for fiberoptic-guided tracheal intubation in ear deformity children.Methods Totally 120 children who were scheduled for elective auricular reconstruction surgery requiring general anaesthesia with tracheal intubation were enrolled in this prospective study. They were randomized to receive either the Ambu Aura-i (Aura-i group) or Air-Q (Air-Q group). The time for successful tracheal intubation was assessed. The attempts for successful device insertion, leak pressures, cuff pressures, fiberoptic grade of laryngeal view, time for removal of the device after endotracheal intubation, and complications were recorded...
December 20, 2016: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28063220/biological-roles-of-glial-fibrillary-acidic-protein-as-a-biomarker-in-cartilage-regenerative-medicine
#6
Sanshiro Kanazawa, Satoru Nishizawa, Tsuyoshi Takato, Kazuto Hoshi
Glial fibrillary acidic protein (GFAP) is an intermediate filament that is expressed in specifically expressed auricular chondrocytes, which are good cell sources of cartilage regenerative medicine. Although our group uses GFAP as a biomarker of matrix production in the cultured auricular chondrocytes, the biological roles of GFAP in auricular chondrocytes has remained unknown. In this study, we demonstrated the biological functions of GFAP in the human and mouse derived auricles to clarify the significance and role with the chondrocytes of GFAP in order to provide useful information for reliable and safe regenerative medicine...
January 7, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28058553/implications-of-sentinel-lymph-node-drainage-to-multiple-basins-in-head-and-neck-melanoma
#7
Camille L Stewart, Ana Gleisner, Jennifer Kwak, Brandon Chapman, Nathan Pearlman, Csaba Gajdos, Martin McCarter, Nicole Kounalakis
BACKGROUND: Sentinel lymph node biopsy (SLNB) for head and neck melanoma is challenging due to unpredictable drainage. We sought to determine the frequency of drainage to multiple lymphatic basins and asked if this was associated with prognosis in a large, single-center cohort. METHODS: We queried patients diagnosed with head and neck melanomas who had a SLNB performed from January 1998 to April 2016. Demographic and clinical characteristics were compared using Student's t test, Pearson chi-square analysis, log-rank test, Wilcoxon-Mann-Whitney test, and Kaplan-Meier curves...
January 5, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28052910/acupuncture-and-pc6-stimulation-for-the-prevention-of-postoperative-nausea-and-vomiting-in-patients-undergoing-elective-laparoscopic-resection-of-colorectal-cancer-a-study-protocol-for-a-three-arm-randomised-pilot-trial
#8
Kun Hyung Kim, Dae Hun Kim, Ji Min Bae, Gyung Mo Son, Kyung Hee Kim, Seung Pyo Hong, Gi Young Yang, Hee Young Kim
INTRODUCTION: This study aims to assess the feasibility of acupuncture and a Pericardium 6 (PC6) wristband as an add-on intervention of antiemetic medication for the prevention of postoperative nausea and vomiting (PONV) in patients undergoing elective laparoscopic colorectal cancer resection. METHODS AND ANALYSIS: A total of 60 participants who are scheduled to undergo elective laparoscopic resection of colorectal cancer will be recruited. An enhanced recovery after surgery protocol using standardised antiemetic medication will be provided for all participants...
January 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28051842/the-use-of-auricular-acupuncture-in-opioid-use-disorder-a-systematic-literature-review
#9
REVIEW
Tanya E Baker, Grace Chang
BACKGROUND AND OBJECTIVES: Opioid use disorder (OUD) is a chronic disease with significant personal, societal, and public health consequences. Even for the minority who receive the most effective evidence-based treatments, morbidity, and mortality remain significant. These facts, along with the recovery movement calling for individualized, holistic, culturally sensitive care, have led to the exploration of adjunctive interventions including acupuncture. Despite hundreds of international trials, however, there is a lack of consensus regarding its efficacy in OUD due in large part to methodological issues of trials to date...
December 2016: American Journal on Addictions
https://www.readbyqxmd.com/read/28043400/dental-issues-in-lacrimo-auriculo-dento-digital-syndrome-an-autosomal-dominant-condition-with-clinical-and-genetic-variability
#10
M J Hajianpour, Hannah Bombei, Scott M Lieberman, Rachael Revell, Rachana Krishna, Robert Gregorsok, Simon Kao, Jeff M Milunsky
BACKGROUND AND OVERVIEW: Lacrimo-auriculo-dento-digital (LADD) syndrome is an autosomal dominant disorder with variable lacrimal and salivary gland hypoplasia and aplasia, auricular anomalies and hearing loss, dental defects and caries, and digital anomalies. CASE DESCRIPTION: The authors present the cases of 2 unrelated children with enamel defects and history of dry mouth leading to recurrent dental caries. The referring diagnoses were Sjögren disease and hypohidrotic ectodermal dysplasia, respectively...
December 30, 2016: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28032171/iatrogenic-through-and-through-conchal-defect-secondary-to-auricular-cartilage-graft
#11
Hyung-Suk Ro, Si-Gyun Roh, Jin Yong Shin, Nae-Ho Lee, Kyung-Moo Yang
BACKGROUND: Over the past few years, conchal cartilage has been most often used in rhinoplasty. The donor site complications following conchal cartilage graft harvesting are scar formation, hematoma formation, and delayed wound healing, although hematoma is one of the most important and common complications. A complete conchal defect as a complication of auricular cartilage graft harvesting has not been previously reported in the literature. The authors report an unusual case of an iatrogenic conchal defect resulting from conchal cartilage graft harvesting that was treated using a posterior auricular island flap...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28032165/an-alternative-posterosuperior-auricular-fascia-flap-for-ear-elevation-during-microtia-reconstruction
#12
Yiyuan Li, Ruhong Zhang, Qun Zhang, Zhicheng Xu, Feng Xu, Datao Li
BACKGROUND: Advances in staged total auricular reconstruction have resulted in improved anterior auricular appearance; however, satisfactory postreconstruction esthetics of the retroauricular fold remain challenging. The postauricular appearance of the reconstructed ear depends largely upon optimizing the covering material. When used as the covering soft tissue for ear elevation, a flap containing primarily the upper portion of the retroauricular fascia has potential advantages over the conventional book cover-type retroauricular fascia flap...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28029563/-use-of-non-vitamin-k-antagonist-oral-anticoagulants-in-primary-care-actua-study
#13
V Barrios, C Escobar, J M Lobos, J Polo, D Vargas
OBJECTIVES: Approximately 40% of patients with non-valvular auricular fibrillation (NVAF) who receive vitamin K antagonists (VKA) in Primary Care in Spain have poor anticoagulation control. The objective of the study Actuación en antiCoagulación, Tratamiento y Uso de anticoagulantes orales de acción directa (ACOD) en Atención primaria (ACTUA) (Action in Coagulation, Treatment and Use of direct oral anticoagulants [DOACs]) in Primary Care) was to analyse the current situation regarding the use of VKA and non-vitamin K antagonist oral anticoagulants (NOACs) in patients with NVAF in Primary Care in Spain and the possible issues arising from it...
October 28, 2016: Semergen
https://www.readbyqxmd.com/read/28027200/vascular-supply-of-the-auricle-anatomical-study-and-applications-to-external-ear-reconstruction
#14
Michaël Hénoux, Florent Espitalier, Antoine Hamel, Brigitte Dréno, Guillaume Michel, Olivier Malard
BACKGROUND: Reliable reconstructive flaps require convenient vascular supply. Thus, precise description of the vascular patterns of external ear is not completely elucidated. OBJECTIVE: This anatomical study aims to provide comprehensive data of the arterial network of the auricular region, anastomosis, and patterns of arterial dependence regarding external ear subunits. MATERIALS AND METHODS: After dyed latex injections in the external carotid artery, eleven auricles have been carefully dissected to examine the vascular network of the auricular region...
January 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28027198/a-topical-anesthetic-and-lidocaine-mixture-for-pain-relief-during-keloid-treatment-a-double-blind-randomized-controlled-trial
#15
Arnik Usanakornkul, Chairat Burusapat
BACKGROUND: Keloids are abnormal overgrowth of collagen fibers, and the first-line treatment includes intralesional injection of triamcinolone acetonide (TA), which is associated with pain. OBJECTIVE: To study the benefit of applying topical anesthetics or a 1:1 mixture of 1% lidocaine and TA at the TA injection site to alleviate pain during keloid treatment. METHODS AND MATERIALS: A double-blind, randomized controlled trial was conducted...
January 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28018436/chromosome-11q13-deletion-syndrome
#16
Yu-Seon Kim, Gun-Ha Kim, Jung Hye Byeon, So-Hee Eun, Baik-Lin Eun
Chromosome 11q13 deletion syndrome has been previously reported as either otodental syndrome or oculo-oto-dental syndrome. The otodental syndrome is characterized by dental abnormalities and high-frequency sensorineural hearing loss, and by ocular coloboma in some cases. The underlying genetic defect causing otodental syndrome is a hemizygous microdeletion involving the FGF3 gene on chromosome 11q13.3. Recently, a new form of severe deafness, microtia (small ear) and small teeth, without the appearance of eye abnormalities, was also reported...
November 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27995371/therapeutic-effect-of-acupuncture-on-the-outcomes-of-in-vitro-fertilization-a-systematic-review-and-meta-analysis
#17
REVIEW
Yi Qian, Xin-Ru Xia, Humphrey Ochin, Cun Huang, Chao Gao, Li Gao, Yu-Gui Cui, Jia-Yin Liu, Yan Meng
PURPOSE: Controversial results have been reported concerning the effect of acupuncture on in vitro fertilization (IVF) outcomes. The current review was conducted to systematically review published studies of the effects of acupuncture on IVF outcomes. METHODS: Women undergoing IVF in randomized controlled trials (RCTs) were evaluated for the effects of acupuncture on IVF outcomes. The treatment groups involved traditional, electrical, laser, auricular, and other acupuncture techniques...
December 19, 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27994492/the-national-acupuncture-detoxification-association-protocol-auricular-acupuncture-to-support-patients-with-substance-abuse-and-behavioral-health-disorders-current-perspectives
#18
Elizabeth B Stuyt, Claudia A Voyles
The National Acupuncture Detoxification Association (NADA)-standardized 3- to 5-point ear acupuncture protocol, born of a community-minded response to turbulent times not unlike today, has evolved into the most widely implemented acupuncture-assisted protocol, not only for substance abuse, but also for broad behavioral health applications. This evolution happened despite inconsistent research support. This review highlights the history of the protocol and the research that followed its development. Promising, early randomized-controlled trials were followed by a mixed field of positive and negative studies that may serve as a whole to prove that NADA, despite its apparent simplicity, is neither a reductive nor an independent treatment, and the need to refine the research approaches...
2016: Substance Abuse and Rehabilitation
https://www.readbyqxmd.com/read/27990114/sparing-surgery-for-the-successful-treatment-of-thyroid-papillary-carcinoma-invading-the-trachea-a-case-report
#19
Denis Kulbakin, Timofey Chekalkin, Marat Muhamedov, Evgeniy Choynzonov, Ji-Hoon Kang, Seung-Baik Kang, Victor Gunther
Published reports on salvage treatment for trachea reconstruction after total thyroidectomy or partial tracheotomy are available, some of them using structures of the trachea itself, auricular cartilage, a musculocutaneous flap, or other methods. In our report, we emphasize the importance of a search for a new material and approach for sparing surgery. The purpose of this article is to describe a case of a successful sparing surgery in a patient with advanced thyroid papillary carcinoma invading the trachea...
September 2016: Case Reports in Oncology
https://www.readbyqxmd.com/read/27987254/application-of-free-serratus-anterior-fascial-flap-for-reconstruction-of-ear-deformity-due-to-hemifacial-microsomia-a-report-of-two-cases
#20
Takashi Nuri, Koichi Ueda, Akira Yamada
Reconstructing congenital auricular defects due to hemifacial microsomia (HFM) is often required to deal with low hairline and defects of the temporal fascia/muscular systems. In this report, we present two cases of HFM patients (16-year-old and 20-year-old) with positional anomaly of the remnant lobule and 95% low hairline, who were treated with serratus anterior fascial flap (SFF) at the second stage of auricular construction. At the first stage, 3D costal cartilage framework was placed following the removal of hair-bearing skin, and was resurfaced with the pericranial flap...
December 17, 2016: Microsurgery
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