Merel L Wemelsfelder, Ronald H G van de Weem, Jessie S Luken, Masja de Haas, René W L M Niessen, C Ellen van der Schoot, Han Hoogeveen, Folarin B Oyebolu, Dick den Hertog, Mart P Janssen
BACKGROUND AND OBJECTIVES: Red blood cell (RBC) transfusions pose a risk of alloantibody development in patients. For patients with increased alloimmunization risk, extended preventive matching is advised, encompassing not only the ABO-D blood groups but also the most clinically relevant minor antigens: C, c, E, e, K, Fya , Fyb , Jka , Jkb , S and s. This study incorporates patient-specific data and the clinical consequences of mismatching into the allocation process. MATERIALS AND METHODS: We have redefined the MINimize Relative Alloimmunization Risks (MINRAR) model to include patient group preferences in selecting RBC units from a finite supply...
January 29, 2024: Vox Sanguinis