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ABO blood type

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https://www.readbyqxmd.com/read/27895641/pneumococcal-polysaccharide-vaccination-elicits-igg-anti-a-b-blood-group-antibodies-in-healthy-individuals-and-patients-with-type-i-diabetes-mellitus
#1
Wendelin Wolfram, Kai M T Sauerwein, Christoph J Binder, Nicole Eibl-Musil, Hermann M Wolf, Michael B Fischer
HYPOTHESIS: Blood group antibodies are natural antibodies that develop early in life in response to cross-reactive environmental antigens in the absence of antigen encounter. Even later in life structural similarities in saccharide composition between environmental antigens such as bacterial polysaccharides and blood group A/B antigens could lead to changes in serum levels, IgM/IgG isotype, and affinity maturation of blood group anti-A/B antibodies. We addressed the question whether immunization with pneumococcal polysaccharide (PnP) vaccine Pneumo 23 Vaccine "Pasteur Merieux" (Pn23) could have such an effect in patients with type I diabetes mellitus (DM I), an autoimmune disease where an aberrant immune response to microbial antigens likely plays a role...
2016: Frontiers in Immunology
https://www.readbyqxmd.com/read/27893352/prevalence-of-antibodies-to-a-new-histo-blood-system-the-fors-system
#2
Carlos Jesus, Camilla Hesse, Clara Rocha, Nádia Osório, Ana Valado, Armando Caseiro, António Gabriel, Lola Svensson, Ali-Reza Moslemi, Wafa Abu Siba, Mahmoud A Srour, Cristina Pereira, Jorge Tomaz, Paulo Teixeira, Fernando Mendes
BACKGROUND: In 1987, three unrelated English families were reported with a putative blood subgroup called Apae. Swedish researchers later found evidence leading to abolishment of the Apae subgroup and establishment instead of the FORS blood group system (System 31 - ISBT, 2012). It is important to know the prevalence of antibodies in order to make the best decisions in transfusion medicine. Cells expressing the Forssman saccharide, such as sheep erythrocytes, are needed to detect the anti-Forssman antibody...
October 24, 2016: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27859559/fut2-non-secretor-status-is-associated-with-type-1-diabetes-susceptibility-in-japanese-children
#3
K Ihara, C Fukano, T Ayabe, M Fukami, T Ogata, T Kawamura, T Urakami, N Kikuchi, I Yokota, K Takemoto, T Mukai, A Nishii, T Kikuchi, T Mori, N Shimura, G Sasaki, R Kizu, N Takubo, S Soneda, T Fujisawa, R Takaya, Z Kizaki, S Kanzaki, K Hanaki, N Matsuura, Y Kasahara, K Kosaka, T Takahashi, K Minamitani, S Matsuo, H Mochizuki, K Kobayashi, A Koike, R Horikawa, S Teno, K Tsubouchi, T Mochizuki, Y Igarashi, S Amemiya, S Sugihara
AIM: To examine the contribution of the FUT2 gene and ABO blood type to the development of Type 1 diabetes in Japanese children. METHODS: We analysed FUT2 variants and ABO genotypes in a total of 531 Japanese children diagnosed with Type 1 diabetes and 448 control subjects. The possible association of FUT2 variants and ABO genotypes with the onset of Type 1 diabetes was statistically examined. RESULTS: The se2 genotype (c.385A>T) of the FUT2 gene was found to confer susceptibility to Type 1A diabetes in a recessive effects model [odds ratio for se2/se2, 1...
November 18, 2016: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/27843110/-recipients-adverse-reactions-in-the-ibn-sina-hospital-of-rabat-state-1999-2013
#4
S Ouadghiri, C Brick, N Benseffaj, O Atouf, M Essakalli
PURPOSE OF STUDY: The declaration of the recipients adverse reactions (RAR) is one of the field haemovigilance activities. It provides an evaluation of transfusion side effects and thus prevents their appearance. The aim of this study is to analyze, over 14 years, the RAR supports reported in Rabat Ibn Sina hospital. PATIENTS AND METHODS: All of the RAR supports sending to the blood transfusion service were analyzed. The data collected from these supports are: clinical characteristics of the patient, type of incident observed and type of labile blood products (LBP) transfused...
November 11, 2016: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/27828195/label-free-optical-sensor-based-on-red-blood-cells-laser-tweezers-raman-spectroscopy-analysis-for-abo-blood-typing
#5
Duo Lin, Zuci Zheng, Qiwen Wang, Hao Huang, Zufang Huang, Yun Yu, Sufang Qiu, Cuncheng Wen, Min Cheng, Shangyuan Feng
The clinical significance of ABO blood typing extends beyond transfusion medicine and is demonstrated to be associated with susceptibility to various diseases, even including cancer. In this study, a home-made laser tweezers Raman spectroscopy (LTRS) system was applied to detect red blood cells (RBCs) with the aim to develop a label-free, simple and objective blood typing method for the first time. High-quality Raman spectra of RBCs in the fingerprint region of 420-1700 cm<sup>-1</sup> can be obtained, meanwhile exciting blood typing results can be achieved, especially with an accuracy of 100% for identifying Type AB from other blood types with the use of multivariate statistical analysis based on principal component analysis (PCA) combined with linear discriminant analysis (LDA)...
October 17, 2016: Optics Express
https://www.readbyqxmd.com/read/27825181/blood-group-o-protects-against-inhibitor-development-in-severe-hemophilia-a-patients
#6
Massimo Franchini, Antonio Coppola, Carlo Mengoli, Gianna Franca Rivolta, Federica Riccardi, Giovanni Di Minno, Annarita Tagliaferri
Increasing evidence supports the link between ABO(H) blood group determinants and hemostasis. In particular, the ABO-related different glycosylation patterns of von Willebrand factor strongly influence its clearance and functional levels, and this may contribute to the inter-individual variations in the half-life of infused Factor VIII (FVIII) in hemophilia A (HA) patients. We investigated the role of ABO blood groups in regulating FVIII immunogenicity by evaluating their distribution in patients with severe (FVIII < 1 IU/dL) HA according to inhibitor development and other known relevant factors...
November 8, 2016: Seminars in Thrombosis and Hemostasis
https://www.readbyqxmd.com/read/27787763/duffy-blood-group-fy-a-fy-b-analysis-using-surface-plasmon-resonance
#7
Whui Lyn Then, Heather McLiesh, Marie-Isabel Aguilar, Gil Garnier
The most widely known blood groups, ABO and RhD, have been extensively observed as having strong antibody-antigen interactions during blood typing. However, not all interactions show the same binding affinity. The Duffy blood group system, where Fy(a) and Fy(b) antigens are the most clinically significant, are only available with an IgG antibody structure, and display weak binding interactions. While current blood typing techniques are well established, methods for quantifying the binding strength are more limited...
December 2016: Biomedical Microdevices
https://www.readbyqxmd.com/read/27778448/intestinal-fatty-acid-binding-protein-ala54thr-polymorphism-is-associated-with-peripheral-atherosclerosis-combined-with-type-2-diabetes-mellitus
#8
Salma A Khattab, Dina M Abo-Elmatty, Maivel H Ghattas, Noha M Mesbah, Eman T Mehanna
BACKGROUND: The intestinal fatty acid binding protein (FABP-2) is expressed in enterocytes and binds saturated and unsaturated long-chain fatty acids. FABP-2 Ala54Thr polymorphism was reported to have an influence on lipid metabolism. This study aimed to assess the relation of this polymorphism with peripheral atherosclerosis combined with type 2 diabetes mellitus in an Egyptian population. METHODS: The study included 100 diabetic patients with peripheral atherosclerosis and 100 control subjects...
October 25, 2016: Journal of Diabetes
https://www.readbyqxmd.com/read/27777156/the-role-of-abo-blood-group-in-cerebral-vasospasm-associated-intracranial-hemorrhage-and-delayed-cerebral-ischemia-in-470-patients-with-subarachnoid-hemorrhage
#9
Daniel Dubinski, Sae-Yeon Won, Jürgen Konczalla, Jan Mersmann, Christof Geisen, Eva Herrmann, Volker Seifert, Christian Senft
OBJECTIVE: Rupture of an intracranial aneurysm usually presents with an acute onset, requires multidisciplinary intensive care treatment, and the overall death and disability rates are high. The ABO blood type is known to play an important role in hemostasis, thrombosis and vascular NO response. The aspect of ABO blood type in onset, clinical progress and outcome after SAH are to date largely unexplored. We conducted this study to elucidate the association of ABO blood type on the occurrence and outcome of aneurysmal SAH...
October 21, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27717418/advances-in-blood-typing
#10
N Quraishy, S Sapatnekar
The clinical importance of blood group antigens relates to their ability to evoke immune antibodies that are capable of causing hemolysis. The most important antigens for safe transfusion are ABO and D (Rh), and typing for these antigens is routinely performed for patients awaiting transfusion, prenatal patients, and blood donors. Typing for other blood group antigens, typically of the Kell, Duffy, Kidd, and MNS blood groups, is sometimes necessary, for patients who have, or are likely to develop antibodies to these antigens...
2016: Advances in Clinical Chemistry
https://www.readbyqxmd.com/read/27687224/real-time-observation-and-automated-measurement-of-red-blood-cells-agglutination-inside-a-passive-microfluidic-biochip-containing-embedded-reagents
#11
Maxime Huet, Myriam Cubizolles, Arnaud Buhot
The process of agglutination is commonly used for the detection of biomarkers like proteins or viruses. The multiple bindings between micrometer sized particles, either latex beads or red blood cells (RBCs), create aggregates that are easily detectable and give qualitative information about the presence of the biomarkers. In most cases, the detection is made by simple naked-eye observation of agglutinates without any access to the kinetics of agglutination. In this study, we address the development of a real-time time observation of RBCs agglutination...
September 20, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27683631/genetic-barriers-in-transplantation-medicine
#12
REVIEW
Hisham A Edinur, Siti M Manaf, Nor F Che Mat
The successful of transplantation is determined by the shared human leukocyte antigens (HLAs) and ABO blood group antigens between donor and recipient. In recent years, killer cell receptor [i.e., killer cell immunoglobulin-like receptor (KIR)] and major histocompatibility complex (MHC) class I chain-related gene molecule (i.e., MICA) were also reported as important determinants of transplant compatibility. At present, several different genotyping techniques (e.g., sequence specific primer and sequence based typing) can be used to characterize blood group, HLA, MICA and KIR and loci...
September 24, 2016: World Journal of Transplantation
https://www.readbyqxmd.com/read/27642338/linezolid-induced-twice-pure-red-cell-aplasia-in-a-patient-with-central-nervous-system-infection-after-allogeneic-stem-cell-transplantation
#13
Wenqing Hu, Bing Shi, Lihui Liu, Shengke He, Liping Ye, DengMei Tian, Yongqing Zhang
Linezolid (LZD), severed as the first oxazolidinone antibiotic, was active against multidrug-resistant gram-positive strains. LZD can induce thrombocytopenia, anemia and leukocytopenia. Currently, reports on pure red cell aplasia (PRCA) cases induced by LZD are relatively rare (4-7). In this paper, we reported a patient with PRCA twice induced by LZD. A 37-year-old man was diagnosed with myelodysplatic syndrome (MDS) and underwent allo-HSCT from an unrelated donor with ABO blood type and leukocyte antigen (HLA)-matching...
2016: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/27616538/effect-of-hepatic-drug-transporter-polymorphisms-on-the-pharmacokinetics-of-mycophenolic-acid-in-patients-with-severe-renal-dysfunction-before-renal-transplantation
#14
Hideaki Kagaya, Takenori Niioka, Mitsuru Saito, Takamitsu Inoue, Kazuyuki Numakura, Tomonori Habuchi, Shigeru Satoh, Masatomo Miura
1. The objective of this study was to examine the association of UGT1A9, SLCO, ABCC polymorphisms with mycophenolic acid (MPA) pharmacokinetics in ABO blood type (ABO) incompatible patients with severe renal dysfunction pre-transplantation. 2. In all patients, on day 14 after beginning mycophenolate mofetil (MMF) treatment (1 week before transplantation) and on day 28 after renal transplantation, samples were collected just prior to and 1, 2, 3, 4, 6, 9 and 12 hours after oral MMF administration. 3. The median dose-adjusted AUC0-12 of MPA after renal transplantation was significantly lower than before transplantation (57...
September 10, 2016: Xenobiotica; the Fate of Foreign Compounds in Biological Systems
https://www.readbyqxmd.com/read/27576883/prognostic-significance-of-blood-type-a-in-patients-with-renal-cell-carcinoma
#15
Kyungtae Ko, Young Hyun Park, Chang Wook Jeong, Ja Hyeon Ku, Hyeon Hoe Kim, Cheol Kwak
PURPOSE: In this study, we evaluated the prognostic significance of the ABO blood type in patients with renal cell carcinoma (RCC) who had undergone partial or radical nephrectomy. MATERIALS AND METHODS: Information on the ABO blood type was obtained from 1750 patients with RCC. A total of 1243 men and 507 women (mean age, 55.41 ± 12.43 years) with RCC who had undergone partial or radical nephrectomy were enrolled in this study. The median follow-up duration was 35...
2016: Urology Journal
https://www.readbyqxmd.com/read/27570428/risk-factor-for-ischemic-type-biliary-lesion-after-abo-incompatible-living-donor-liver-transplantation
#16
Jun Bae Bang, Bong-Wan Kim, Young Bae Kim, Hee-Jung Wang, Hyun Yeong Lee, Joohyun Sim, Taegyu Kim, Kyeong Lok Lee, Xu-Guang Hu, Wei Mao
AIM: To evaluate the risk factors for ischemic-type biliary lesion (ITBL) after ABO-incompatible (ABO-I) adult living donor liver transplantation (ALDLT). METHODS: Among 141 ALDLTs performed in our hospital between 2008 and 2014, 27 (19%) were ABO-I ALDLT and 114 were ABO-identical/compatible ALDLT. In this study, we extensively analyzed the clinico-pathological data of the 27 ABO-I recipients to determine the risk factors for ITBL after ABO-I ALDLT. All ABO-I ALDLT recipients underwent an identical B-cell depletion protocol with preoperative rituximab, plasma exchange (PE), and operative splenectomy...
August 14, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27569078/relationship-between-abo-blood-groups-and-head-and-neck-cancer-among-greek-patients
#17
Kassiani Kakava, Ioannis Karelas, Ioannis Koutrafouris, Savvas Damianidis, Paulos Stampouloglou, Georgios Papadakis, Antonios Xenos, Foteini Krania, Paulos Sarof, Georgios Tasopoulos, Nikolaos Petridis
PURPOSE: We examined the association of ABO blood groups with the different types of head and neck cancers. METHODS: 195 diagnosed cases and 801 controls were selected from a Greek tertiary cancer center. Information regarding type of head and neck cancer and ABO blood group was collected and registered. RESULTS: The O blood group was found to be most prevalent followed by A, B and AB among the controls, whereas blood group A followed by O, B and AB was most prevalent among cancer patients...
May 2016: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/27561786/irregular-antibodies-in-no-hemolytic-autoimmune-diseases-are-able-to-induce-erythrophagocytosis
#18
Paola Ester López-Díaz, María Del Rocío Ruiz-Olivera, Luis Alberto Hernández-Osorio, Jaime Vargas-Arzola, Xareni Valle-Jiménez, Sergio Roberto Aguilar-Ruiz, Honorio Torres-Aguilar
Irregular antibodies are produced by alloimmunization because of pregnancies or blood transfusions. They are called "irregular" due to target erythrocyte antigens from "rare blood systems," those different from the ABO system. Irregular antibodies have been widely investigated in immunohematology since their presence in blood donors may lead to difficulties in blood typing and in blood cross-matching, or to induce hemolytic transfusion reactions. Nevertheless, their incidence and participation in the physiopathology of autoimmune diseases have not been thoroughly studied...
August 25, 2016: Immunologic Research
https://www.readbyqxmd.com/read/27557546/risk-assessment-of-gene-variants-for-neonatal-hyperbilirubinemia-in-taiwan
#19
Yi-Hao Weng, Ya-Wen Chiu, Shao-Wen Cheng, Chun-Yuh Yang
BACKGROUND: Hyperbilirubinemia is a common disorder during neonatal period in Taiwan. Gene variants may play an important role in the development of neonatal hyperbilirubinemia. The current study investigated the association between neonatal hyperbilirubinemia and common gene variants involving the production and metabolism of bilirubin. METHODS: This prospective study enrolled 444 healthy infants born in the Chang Gung Memorial Hospital at Taipei from 2013-2015...
2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27546586/a-novel-abo-o-allele-caused-by-a-large-deletion-covering-two-exons-of-the-abo-gene-identified-in-a-caucasian-family-showing-discrepant-abo-blood-typing-results
#20
Eva M Matzhold, Camilla Drexler, Thomas Wagner
BACKGROUND: The presence of ABO subgroup alleles and unusual O alleles often is associated with discrepant serologic findings in ABO blood group typing. In the ABO gene of a Caucasian female and her daughters who had aberrant ABO phenotypes, a novel ABO O allele characterized by a large deletion that included two exons was identified. METHODS: ABO phenotypes were determined by standard agglutination tests and adsorption-elution studies. Allele-specific sequencing analyses of the ABO gene as well as messenger RNA transcripts were carried out...
August 21, 2016: Transfusion
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