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https://www.readbyqxmd.com/read/29195700/effectiveness-of-a-clinical-knowledge-support-system-for-reducing-diagnostic-errors-in-outpatient-care-in-japan-a-retrospective-study
#1
Taro Shimizu, Takaaki Nemoto, Yasuharu Tokuda
Clinical evidence has indicated the effectiveness of computer-based systems for preventing and reducing diagnostic errors. Our study aimed to evaluate the effectiveness of UpToDate, a computer-based clinical knowledge management system, for reducing diagnostic errors. We retrospectively identified 100 patients who visited an outpatient department in a community-based hospital from July 2014 to June 2015. Fifty patients (exposure group) were seen by UpToDate-equipped physicians and another 50 (control group) were seen by UpToDate-unequipped physicians...
January 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29150475/uptodate-adherence-to-grade-criteria-for-strong-recommendations-an-analytical-survey
#2
Thomas Agoritsas, Arnaud Merglen, Anja Fog Heen, Annette Kristiansen, Ignacio Neumann, Juan P Brito, Romina Brignardello-Petersen, Paul E Alexander, David M Rind, Per O Vandvik, Gordon H Guyatt
INTRODUCTION: UpToDate is widely used by clinicians worldwide and includes more than 9400 recommendations that apply the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework. GRADE guidance warns against strong recommendations when certainty of the evidence is low or very low (discordant recommendations) but has identified five paradigmatic situations in which discordant recommendations may be justified. OBJECTIVES: Our objective was to document the strength of recommendations in UpToDate and assess the frequency and appropriateness of discordant recommendations...
November 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29108136/application-and-optimisation-of-the-comparison-on-extreme-laboratory-tests-cert-algorithm-for-detection-of-adverse-drug-reactions-transferability-across-national-boundaries
#3
Mun Yee Tham, Qing Ye, Pei San Ang, Liza Y Fan, Dukyong Yoon, Rae Woong Park, Zheng Jye Ling, James W Yip, Bee Choo Tai, Stephen Jw Evans, Cynthia Sung
PURPOSE: The Singapore regulatory agency for health products (Health Sciences Authority), in performing active surveillance of medicines and their potential harms, is open to new methods to achieve this goal. Laboratory tests are a potential source of data for this purpose. We have examined the performance of the Comparison on Extreme Laboratory Tests (CERT) algorithm, developed by Ajou University, Korea, as a potential tool for adverse drug reaction detection based on the electronic medical records of the Singapore health care system...
November 6, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29089291/comparison-of-the-impact-of-wikipedia-uptodate-and-a-digital-textbook-on-short-term-knowledge-acquisition-among-medical-students-randomized-controlled-trial-of-three-web-based-resources
#4
Michael A Scaffidi, Rishad Khan, Christopher Wang, Daniela Keren, Cindy Tsui, Ankit Garg, Simarjeet Brar, Kamesha Valoo, Michael Bonert, Jacob F de Wolff, James Heilman, Samir C Grover
BACKGROUND: Web-based resources are commonly used by medical students to supplement curricular material. Three commonly used resources are UpToDate (Wolters Kluwer Inc), digital textbooks, and Wikipedia; there are concerns, however, regarding Wikipedia's reliability and accuracy. OBJECTIVE: The aim of this study was to evaluate the impact of Wikipedia use on medical students' short-term knowledge acquisition compared with UpToDate and a digital textbook. METHODS: This was a prospective, nonblinded, three-arm randomized trial...
October 31, 2017: JMIR Medical Education
https://www.readbyqxmd.com/read/29034722/the-efficacy-of-apaziquone-in-the-treatment-of-bladder-cancer
#5
Francisco Caramés Masana, Theo M de Reijke
Bladder cancer is nowadays a common tumor. Non-muscle invasive bladder cancer (NMIBC) has still chances of recurrence and progression in spite of surgery and adjuvant treatments. New therapies are being developed to reduce these percentages with less adverse effects - Apaziquone (EO9) is an example. Areas covered: A literature search has been performed using Pubmed, UpToDate and Google verified information (mainly from Food and Drug Administration and Spectrum Pharmaceutics websites). We have included data from the most representative clinical trials and reviews published...
October 20, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28852652/postpartum-depression-risk-factors-a-narrative-review
#6
REVIEW
Maryam Ghaedrahmati, Ashraf Kazemi, Gholamreza Kheirabadi, Amrollah Ebrahimi, Masood Bahrami
Postpartum depression is a debilitating mental disorder with a high prevalence. The aim of this study was review of the related studies. In this narrative review, we report studies that investigated risk factors of postpartum depression by searching the database, Scopus, PubMed, ScienceDirect, Uptodate, Proquest in the period 2000-2015 published articles about the factors associated with postpartum depression were assessed in Farsi and English. The search strategy included a combination of keywords include postpartum depression and risk factors or obstetrical history, social factors, or biological factors...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/28810192/vaginal-and-laparoscopic-hysterectomy-as-an-outpatient-procedure-a-systematic-review
#7
Suzanne J Dedden, Peggy M A J Geomini, Judith A F Huirne, Marlies Y Bongers
OBJECTIVES: Laparoscopic and vaginal hysterectomies are common gynaecological procedures. Same-day discharge is usual care in various gynaecological procedures like laparoscopic sterilisation and laparoscopic oophorectomies. In major procedures like vaginal or laparoscopic hysterectomy patients are usually admitted overnight. We systematically reviewed the literature to identify complications, risk factors for (re)admittance, financial consequences and patient satisfaction of same-day discharge after a vaginal or laparoscopic hysterectomy...
September 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28806791/effect-of-access-to-an-electronic-medical-resource-on-performance-characteristics-of-a-certification-examination-a-randomized-controlled-trial
#8
RANDOMIZED CONTROLLED TRIAL
Rebecca S Lipner, Bradley G Brossman, Kelli M Samonte, Steven J Durning
Background: Electronic resources are increasingly used in medical practice. Their use during high-stakes certification examinations has been advocated by many experts, but whether doing so would affect the capacity to differentiate between high and low abilities is unknown. Objective: To determine the effect of electronic resources on examination performance characteristics. Design: Randomized controlled trial. Setting: Medical certification program...
September 5, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28762228/-a-systematic-review-and-meta-analysis-of-the-pros-and-cons-of-consuming-liquids-preoperatively
#9
REVIEW
Fang-Tzu Lin, Tsai-Rung Lin, Chia-Wei Liao, Shu-Hui Chen
BACKGROUND: Preoperative anesthesia long time fasting, may increase patient hemodynamic instability during surgery and may affect the patient's post-surgery electrolyte balance. No meta-analysis has been conducted to explore the effects of preoperative liquid intake amount on gastric fluid PH, gastric fluid volume, surgery inhalation of pulmonary complications, and patient self-perceptions quality of care systematic review and meta-analysis of the literature. PURPOSE: To assess the pros and cons of preoperative liquid intake using a systematic review of the literature...
August 2017: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/28759866/oral-health-impacts-of-medications-used-to-treat-mental-illness
#10
N Cockburn, A Pradhan, M W Taing, S Kisely, P J Ford
BACKGROUND: Many psychotropic medications affect oral health. This review identified oral side effects for antidepressant, antipsychotic, anticonvulsant, antianxiety and sedative drugs that are recommended in Australia for the management of common mental illnesses and provides recommendations to manage these side-effects. METHODS: The Australian Therapeutic Guidelines and the Australian Medicines Handbook were searched for medications used to treat common mental health conditions...
December 1, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28682431/uptodate-in-the-assessment-and-management-of-intraductal-papillary-mucinous-neoplasms-of-the-pancreas
#11
D Pagliari, A Saviano, M L Serricchio, A A Dal Lago, M G Brizi, F Lanza, R Manfredi, A Gasbarrini, F Attili
Intraductal Papillary Mucinous Neoplasms (IPMNs) are the most common cystic tumors of the pancreas and are considered premalignant lesions. IPMNs are characterized by the papillary growth of the ductal epithelium with rich mucin production, which is responsible for cystic segmental or diffuse dilatation of the main pancreatic duct (MPD) and/or its branches. According to the different involvement of pancreatic duct system, IPMNs are divided into main duct type (MD-IPMN), branch duct type (BD-IPMN), and mixed type (MT-IPMN)...
June 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28503217/assessment-and-use-of-drug-information-references-in-utah-pharmacies
#12
Krystal L Moorman, Elyse A Macdonald, Anthony Trovato, Casey R Tak
OBJECTIVE: To determine which drug references Utah pharmacists use most frequently. To determine which types of drug information questions are most commonly asked, and whether Utah pharmacists have access to adequate references to respond to these questions. METHODS: A 19-question survey was created using Qualtrics, LLC (Provo, Utah) software. An electronic survey link was sent to 1,431 pharmacists with a valid e-mail address listed in the Department of Professional Licensing database...
January 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/28491302/fibromyalgia-in-beh%C3%A3-et-s-disease-a-narrative-review
#13
Claire Jobanputra, Roberta H Richey, Jagdish Nair, Robert J Moots, Andreas Goebel
INTRODUCTION: Fibromyalgia is characterised by chronic widespread pain and tenderness. It has often been reported to occur concomitantly with chronic rheumatological conditions. Behçet's disease is a chronic relapsing, multisystem, autoinflammatory disease. There is only limited understanding of a potential relationship between fibromyalgia and Behçet's disease. AIM: Given the potential detrimental influence of pain on the outcome of chronic disease, the aim of this narrative review is to gain an understanding of the incidence and presentation of fibromyalgia in Behçet's disease...
May 2017: British Journal of Pain
https://www.readbyqxmd.com/read/28460776/pathophysiology-of-the-cardio-renal-syndromes-types-1-5-an-uptodate
#14
REVIEW
L Di Lullo, A Bellasi, V Barbera, D Russo, L Russo, B Di Iorio, M Cozzolino, C Ronco
According to the recent definition proposed by the Consensus conference on Acute Dialysis Quality Initiative Group, the term cardio-renal syndrome (CRS) has been used to define different clinical conditions in which heart and kidney dysfunction overlap. Type 1 CRS (acute cardio- renal syndrome) is characterized by acute worsening of cardiac function leading to AKI (5, 6) in the setting of active cardiac disease such as ADHF, while type - 2 CRS occurs in a setting of chronic heart disease. Type 3 CRS is closely link to acute kidney injury (AKI), while type 4 represent cardiovascular involvement in chronic kidney disese (CKD) patients...
March 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28448778/economic-impact-of-above-label-dosing-with-etanercept-adalimumab-or-ustekinumab-in-patients-with-psoriasis
#15
Steven R Feldman, Yang Zhao, Huanxue Zhou, Vivian Herrera, Haijun Tian, Yunfeng Li
BACKGROUND: Patients with moderate-to-severe psoriasis may be treated with above-label doses of biologics in an attempt to optimize outcomes. Dose escalation will have an effect on the cost of treatment. OBJECTIVE: To examine costs related to above-label use of etanercept, adalimumab, and ustekinumab among patients with moderate-to-severe psoriasis. METHODS: A retrospective study was performed using a large U.S. claims database. Patients were included in the study if they were aged ≥ 18 years with a diagnosis of psoriasis (excluding psoriatic arthritis) and had at least 1 medication fill for etanercept, adalimumab, or ustekinumab between January 1, 2011, and June 30, 2012...
May 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28428332/education-in-nephrology-fellowship-a-survey-based-needs-assessment
#16
Robert W Rope, Kurtis A Pivert, Mark G Parker, Stephen M Sozio, Sylvia Bereknyei Merell
Educational needs assessments for nephrology fellowship training are limited. This study assessed fellows' perceptions of current educational needs and interest in novel modalities that may improve their educational experience and quantified educational resources used by programs and fellows. We distributed a seven-question electronic survey to all United States-based fellows receiving complimentary American Society of Nephrology (ASN) membership at the end of the 2015-2016 academic year in conjunction with the ASN Nephrology Fellows Survey...
July 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28421272/-the-pathology-of-adverse-events-with-immune-checkpoint-inhibitors
#17
V H Koelzer, K Glatz, L Bubendorf, A Weber, A Gaspert, G Cathomas, A Lugli, A Zippelius, W Kempf, K D Mertz
BACKGROUND: Immunotherapy has gained importance with the development of new effective cancer treatments. Immune checkpoint inhibitors (ICI) are monoclonal antibodies that promote T‑cell mediated tumor immune rejection. Checkpoint blockade also carries the risk of inducing autoimmune reactions ("immune related adverse events", irAEs). The diagnosis and classification of irAEs constitute a new and important field in pathology. AIM: Practice-oriented review of the diagnosis and classification of irAEs...
May 2017: Der Pathologe
https://www.readbyqxmd.com/read/28322678/staying-afloat-in-a-sea-of-information-point-of-care-resources
#18
REVIEW
Rebecca Andrews, Neil Mehta, Jack Maypole, Stephen A Martin
Physicians can use a variety of electronic resources at the point of care to help them make decisions about patient management. The authors address the need for these resources, characterize the elements of good resources, and compare several popular ones, ie, Clinical Evidence, Dynamed, Evidence Essentials, First Consult, Medscape, and UpToDate.
March 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28286821/smartphones-and-medical-applications-in-the-emergency-department-daily-practice
#19
Amirhosein Jahanshir, Ehsan Karimialavijeh, Hojjat Sheikh, Motahar Vahedi, Mehdi Momeni
INTRODUCTION: Medical applications help physicians to make more rapid and evidence based decisions that may provide better patient care. This study aimed to determine the extent to which smart phones and medical applications are integrated in the emergency department daily practice. METHOD: In a cross sectional study, a modified standard questionnaire (Payne et al.) consisting of demographic data and information regarding quality and quantity of smartphone and medical app utilization was sent to emergency-medicine residents and interns twice (two weeks apart), in January 2015...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28237370/perioperative-management-of-patients-with-cardiac-implantable-electronic-devices
#20
R Poveda-Jaramillo, H D Castro-Arias, C Vallejo-Zarate, L F Ramos-Hurtado
The use of implantable cardiac devices in people of all ages is increasing, especially in the elderly population: patients with pacemakers, cardioverter-defibrillators or cardiac resynchronization therapy devices regularly present for surgery for non-cardiac causes. This review was made in order to collect and analyze the latest evidence for the proper management of implantable cardiac devices in the perioperative period. Through a detailed exploration of PubMed, Academic Search Complete (EBSCO), ClinicalKey, Cochrane (Ovid), the search software UpToDate, textbooks and patents freely available to the public on Google, we selected 33 monographs, which matched the objectives of this publication...
May 2017: Revista Española de Anestesiología y Reanimación
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