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https://www.readbyqxmd.com/read/28428332/education-in-nephrology-fellowship-a-survey-based-needs-assessment
#1
Robert W Rope, Kurtis A Pivert, Mark G Parker, Stephen M Sozio, Sylvia Bereknyei Merell
Educational needs assessments for nephrology fellowship training are limited. This study assessed fellows' perceptions of current educational needs and interest in novel modalities that may improve their educational experience and quantified educational resources used by programs and fellows. We distributed a seven-question electronic survey to all United States-based fellows receiving complimentary American Society of Nephrology (ASN) membership at the end of the 2015-2016 academic year in conjunction with the ASN Nephrology Fellows Survey...
April 20, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28421272/-the-pathology-of-adverse-events-with-immune-checkpoint-inhibitors
#2
V H Koelzer, K Glatz, L Bubendorf, A Weber, A Gaspert, G Cathomas, A Lugli, A Zippelius, W Kempf, K D Mertz
BACKGROUND: Immunotherapy has gained importance with the development of new effective cancer treatments. Immune checkpoint inhibitors (ICI) are monoclonal antibodies that promote T‑cell mediated tumor immune rejection. Checkpoint blockade also carries the risk of inducing autoimmune reactions ("immune related adverse events", irAEs). The diagnosis and classification of irAEs constitute a new and important field in pathology. AIM: Practice-oriented review of the diagnosis and classification of irAEs...
April 18, 2017: Der Pathologe
https://www.readbyqxmd.com/read/28322678/staying-afloat-in-a-sea-of-information-point-of-care-resources
#3
REVIEW
Rebecca Andrews, Neil Mehta, Jack Maypole, Stephen A Martin
Physicians can use a variety of electronic resources at the point of care to help them make decisions about patient management. The authors address the need for these resources, characterize the elements of good resources, and compare several popular ones, ie, Clinical Evidence, Dynamed, Evidence Essentials, First Consult, Medscape, and UpToDate.
March 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28286821/smartphones-and-medical-applications-in-the-emergency-department-daily-practice
#4
Amirhosein Jahanshir, Ehsan Karimialavijeh, Hojjat Sheikh, Motahar Vahedi, Mehdi Momeni
INTRODUCTION: Medical applications help physicians to make more rapid and evidence based decisions that may provide better patient care. This study aimed to determine the extent to which smart phones and medical applications are integrated in the emergency department daily practice. METHOD: In a cross sectional study, a modified standard questionnaire (Payne et al.) consisting of demographic data and information regarding quality and quantity of smartphone and medical app utilization was sent to emergency-medicine residents and interns twice (two weeks apart), in January 2015...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28237370/perioperative-management-of-patients-with-cardiac-implantable-electronic-devices
#5
R Poveda-Jaramillo, H D Castro-Arias, C Vallejo-Zarate, L F Ramos-Hurtado
The use of implantable cardiac devices in people of all ages is increasing, especially in the elderly population: patients with pacemakers, cardioverter-defibrillators or cardiac resynchronization therapy devices regularly present for surgery for non-cardiac causes. This review was made in order to collect and analyze the latest evidence for the proper management of implantable cardiac devices in the perioperative period. Through a detailed exploration of PubMed, Academic Search Complete (EBSCO), ClinicalKey, Cochrane (Ovid), the search software UpToDate, textbooks and patents freely available to the public on Google, we selected 33 monographs, which matched the objectives of this publication...
May 2017: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/28236797/community-acquired-pneumonia-caused-by-methicillin-resistant-staphylococcus-aureus-in-critically-ill-patients-systematic-review
#6
Nuria Carballo, Marta De Antonio-Cuscó, Daniel Echeverría-Esnal, Sonia Luque, Esther Salas, Santiago Grau
INTRODUCTION: Community-acquired pneumonia (CAP) is associated with high morbidity and mortality rates. Despite methicillin-resistant Staphylococcus aureus (MRSA) having often been associated with nosocomial pneumonia, the condition of some MRSA CAP patients is severe enough to warrant their being admitted to ICU. OBJECTIVE: The purpose of this study is to conduct a systematic review of the literature on antibiotic treatment of MRSA CAP in critically-ill patients...
March 1, 2017: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/28229252/pain-in-patients-with-pancreatic-cancer-prevalence-mechanisms-management-and-future-developments
#7
REVIEW
Andreas I Koulouris, Paul Banim, Andrew R Hart
Pain affects approximately 80% of patients with pancreatic cancer, with half requiring strong opioid analgesia, namely: morphine-based drugs on step three of the WHO analgesic ladder (as opposed to the weak opioids: codeine and tramadol). The presence of pain is associated with reduced survival. This article reviews the literature regarding pain: prevalence, mechanisms, pharmacological, and endoscopic treatments and identifies areas for research to develop individualized patient pain management pathways. The online literature review was conducted through: PubMed, Clinical Key, Uptodate, and NICE Evidence...
April 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28173850/new-horizons-in-treatment-of-osteoporosis
#8
REVIEW
Ozra Tabatabaei-Malazy, Pooneh Salari, Patricia Khashayar, Bagher Larijani
BACKGROUND: Prevalence of osteoporosis is increasing both in developed and developing countries. Due to rapid growth in the burden and cost of osteoporosis, worldwide, it seems reasonable to focus on the reduction of fractures as the main goal of treatment. Although, efficient pharmacological agents are available for the treatment of osteoporosis, there still remains a need to more specific drugs with less adverse effects. MAIN BODY: This review article provides a brief update on the pathogenesis, presenting current pharmacological products approved by the US Food and Drug Administration (FDA) or Europe, and also newer therapeutic agents to treat osteoporosis according to the clinical trial data available at PubMed, UpToDate, International Osteoporosis Foundation (IOF), and clinical practice guidelines...
February 7, 2017: Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/28151071/strategies-to-improve-self-management-in-heart-failure-patients
#9
Mehnosh Toback, Nancy Clark
BACKGROUND: Heart failure is one of the most common causes of hospitalization, hospital readmission and death. Patients with heart failure have many complications, with multiple co-existing diagnoses which result in polypharmacy. Following instructions provided by many physicians, medication adjustments based on changes in their symptoms are required. Behavioral adjustments concerning diet and exercise regime are recommended. Therefore, the patient plays a crucial role in the management of heart failure...
February 19, 2017: Contemporary Nurse
https://www.readbyqxmd.com/read/28110807/treatment-options-for-patellar-tendinopathy-a%C3%A2-systematic-review
#10
REVIEW
Joshua S Everhart, Devon Cole, John H Sojka, John D Higgins, Robert A Magnussen, Laura C Schmitt, David C Flanigan
PURPOSE: To compare the efficacy of common invasive and noninvasive patellar tendinopathy (PT) treatment strategies. METHODS: A systematic search was performed in PubMed, Google Scholar, CINAHL, UptoDate, Cochrane Reviews, and SPORTDiscus. Fifteen studies met the following inclusion criteria: (1) therapeutic outcome trial for PT, and (2) Victorian Institute of Sports Assessment was used to assess symptom severity at follow-up. Methodological quality and reporting bias were evaluated with a modified Coleman score and Begg's and Egger's tests of bias, respectively...
April 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28095946/electroconvulsive-therapy-ect-for-treating-agitation-in-dementia-major-neurocognitive-disorder-a-promising-option
#11
Oliver M Glass, Brent P Forester, Adriana P Hermida
BACKGROUND: Agitation in patients with dementia increases caretaker burden, increases healthcare costs, and worsens the patient's quality of life. Antipsychotic medications, commonly used for the treatment of agitation in patients with dementia have a box warning from the FDA for elevated mortality risk. Electroconvulsive therapy (ECT) has made significant advances over the past several years, and is efficacious in treating a wide range of psychiatric conditions. We provide a systematic review of published literature regarding the efficacy of ECT for the treatment of agitation in patients with dementia (major neurocognitive disorder)...
May 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28064261/clinical-effects-of-prebiotics-in-pediatric-population
#12
Rok Orel, Lea Vodušek Reberšak
CONTEXT: Prebiotics are non-digestible components of food that in a selective manner trigger the expansion of microbes in the gut with valuable effects for the health of the host. In our document, current literature pertaining to the clinical effects of the use of prebiotics for the treatment and prevention of some common pediatric pathology such as infantile colic, constipation, absorption of minerals, weight gain, diarrhea, respiratory infections, and eczema is reviewed. EVIDENCE: Data was collected through search of the MEDLINE, PubMed, UpToDate, Cochrane Database of Systemic Reviews, and the Cochrane Controlled Trials Register database as well as through references from relevant articles, all until September 2015...
December 15, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/28048834/th-ef-bra-03-assessment-of-data-driven-respiratory-motion-compensation-methods-for-4d-cbct-image-registration-and-reconstruction-using-clinical-datasets
#13
M J Riblett, E Weiss, G E Christensen, G D Hugo
PURPOSE: To evaluate the performance of a 4D-CBCT registration and reconstruction method that corrects for respiratory motion and enhances image quality under clinically relevant conditions. METHODS: Building on previous work, which tested feasibility of a motion-compensation workflow using image datasets superior to clinical acquisitions, this study assesses workflow performance under clinical conditions in terms of image quality improvement. Evaluated workflows utilized a combination of groupwise deformable image registration (DIR) and image reconstruction...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048633/tu-ab-202-08-generating-organ-surfaces-to-overcome-random-contouring-errors-and-slice-thickness-variations-on-multimodality-images
#14
S Oh, E Weiss, G Christensen, G Hugo, J Williamson
PURPOSE: To propose a new method that generates smooth organ surface meshes that overcomes random contouring errors and volume averaging artifacts for hollow organs. METHODS: The proposed contour-to-smooth mesh generation method (CSMG) consists of two parts; 1) reconstructing the inner and outer surfaces of the hollow organ with triangular meshes based on parametric active surface (PAS) and 2) modifying the reconstructed inner surface in order to satisfy minimum wall thickness constraints and matching the patient's known organ wall volume...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048226/su-f-r-35-repeatability-of-texture-features-in-t1-and-t2-weighted-mr-images
#15
R Mahon, E Weiss, J Ford, K Karki, G Hugo
PURPOSE: To evaluate repeatability of lung tumor texture features from inspiration/expiration MR image pairs for potential use in patient specific care models and applications. Repeatability is a desirable and necessary characteristic of features included in such models. METHODS: T1-weighted Volumetric Interpolation Breath-Hold Examination (VIBE) and/or T2-weighted MRI scans were acquired for 15 patients with non-small cell lung cancer before and during radiotherapy for a total of 32 and 34 same session inspiration-expiration breath-hold image pairs respectively...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048098/su-f-j-67-dosimetric-changes-during-radiotherapy-in-lung-cancer-patients-with-atelectasis
#16
C Guy, E Weiss, N Jan, L Reshko, G Christensen, G Hugo
PURPOSE: Large geometric changes which occur during thoracic radiotherapy alter normal anatomy and target position and may induce clinically important dose changes. This study investigates variation of organ-at-risk (OAR) dose caused by atelectasis resolution during radiotherapy. METHODS: 3D IMRT treatment plans were obtained for 14 non-small-cell lung cancer patients. Dose of the clinical plan was recalculated on a baseline scan in which lung was collapsed and on a midtreatment scan in which lung re-aeration had occurred...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047251/tu-h-campus-jep2-02-interobserver-variability-of-ct-pet-ct-and-mri-based-primary-tumor-delineation-for-lung-cancer
#17
K Karki, G Hugo, S Saraiya, N Jan, J Schuster, M Schutzer, L Fahrner, R Groves, J Ford, E Weiss
PURPOSE: Target delineation in lung cancer radiotherapy has, in general, large variability. MRI has so far not been investigated in detail for lung cancer delineation variability. The purpose of this study is to investigate delineation variability for lung tumors using MRI and compare it to CT alone and PET-CT based delineations. METHODS: Seven physicians delineated the primary tumor volumes of nine patients for the following scenarios: (1) CT only; (2) post-contrast T1-weighted MRI registered with diffusion-weighted MRI; and (3) PET-CT fusion images...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046287/su-f-j-120-evaluation-of-the-combined-effect-of-body-orientation-and-breathing-on-organ-movement-in-thorax-using-multi-step-deformable-image-registration
#18
C Guy, E Weiss, S Che, W Sleeman, N Mukhopadhyay, M Rosu
PURPOSE: Use deformable registration to map more complex anatomies that include changes associated with both different body positions and breathing, and evaluate the resultant respiratory excursions for tumors and relevant organs at risk. METHODS: Same-day exhale and inhale datasets from prone and supine 4D CT scans of lung cancer patients have been registered using the Elastix software package through a 3 step process: (1) rigid registration for bony alignment (2) deformable multiresolution B-Spline registration of entire anatomy (3) deformable multiresolution B-Spline registration of lung parenchyma (to improve lung vasculature alignment)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28017971/labour-and-childbirth-after-previous-caesarean-section-recommendations-of-the-austrian-society-of-obstetrics-and-gynaecology-oeggg
#19
P Reif, C Brezinka, T Fischer, P Husslein, U Lang, A Ramoni, H Zeisler, P Klaritsch
The new expert recommendation from the Austrian Society of Obstetrics and Gynaecology (OEGGG) comprises an interpretation and summary of guidelines from the leading specialist organisations worldwide (RCOG, ACOG, SOGC, CNGOF, WHO, NIH, NICE, UpToDate). In essence it outlines alternatives to the direct pathway to elective repeat caesarean section (ERCS). In so doing it aligns with international trends, according to which a differentiated, individualised clinical approach is recommended that considers benefits and risks to both mother and child, provides detailed counselling and takes the patient's wishes into account...
December 2016: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28001190/an-update-on-pathology-of-iga-nephropathy
#20
Maria Fernanda Soares
IgA Nephropathy (IgAN) is the commonest of the glomerular diseases in the world. Its progression rate of 30-40% of the cases em 20-30 years makes IgAN an important healthcare issue in Nephrology. Diagnosis of IgAN depends on biopsy findings, particularly at immunofluorescence microscopy. The frequence of IgAN diagnosis is variable in different populations and depends on screening and biopsy indication policies. IgAN pathogenesis is considered multifactorial; its primordial defect is the production of galactosis-deficient IgA molecules...
December 2016: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
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