keyword
MENU ▼
Read by QxMD icon Read
search

Asbestosis

keyword
https://www.readbyqxmd.com/read/28593073/cancer-incidence-in-asbestos-exposed-workers-an-update-on-four-finnish-cohorts
#1
Pia Nynäs, Eero Pukkala, Harri Vainio, Panu Oksa
BACKGROUND: We assessed the cancer risks of four different Finnish asbestos-exposed cohorts. We also explored if the cohorts with varying profiles of asbestos exposure exhibited varying relative risks of cancer. METHODS: The incident cancer cases for the asbestos-exposed worker cohorts were updated to the end of 2012 using the files of the Finnish Cancer Registry. The previously formed cohorts consisted of asbestos mine workers, asbestosis patients, asbestos sprayers, and workers who had taken part in a screening study based on asbestos exposure at work...
June 2017: Safety and Health At Work
https://www.readbyqxmd.com/read/28588347/glycoprotein-ykl-40-levels-in-plasma-are-associated-with-fibrotic-changes-on-hrct-in-asbestos-exposed-subjects
#2
Tuija Väänänen, Lauri Lehtimäki, Katriina Vuolteenaho, Mari Hämäläinen, Panu Oksa, Tuula Vierikko, Ritva Järvenpää, Jukka Uitti, Hannu Kankaanranta, Eeva Moilanen
YKL-40 is a chitinase-like glycoprotein produced by alternatively activated macrophages that are associated with wound healing and fibrosis. Asbestosis is a chronic asbestos-induced lung disease, in which injury of epithelial cells and activation of alveolar macrophages lead to enhanced collagen production and fibrosis. We studied if YKL-40 is related to inflammation, fibrosis, and/or lung function in subjects exposed to asbestosis. Venous blood samples were collected from 85 men with moderate or heavy occupational asbestos exposure and from 28 healthy, age-matched controls...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28558669/calretinin-as-a-blood-based-biomarker-for-mesothelioma
#3
Georg Johnen, Katarzyna Gawrych, Irina Raiko, Swaantje Casjens, Beate Pesch, Daniel G Weber, Dirk Taeger, Martin Lehnert, Jens Kollmeier, Torsten Bauer, Arthur W Musk, Bruce W S Robinson, Thomas Brüning, Jenette Creaney
BACKGROUND: Malignant mesothelioma (MM) is a deadly cancer mainly caused by previous exposure to asbestos. With a latency period up to 50 years the incidence of MM is still increasing, even in countries that banned asbestos. Secondary prevention has been established to provide persons at risk regular health examinations. An earlier detection with tumor markers might improve therapeutic options. Previously, we have developed a new blood-based assay for the protein marker calretinin. Aim of this study was the verification of the assay in an independent study population and comparison with the established marker mesothelin...
May 30, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28481375/pleural-mesothelioma-in-household-members-of-asbestos-exposed-workers-in-friuli-venezia-giulia-italy
#4
Flavia D' Agostin, Paola de Michieli, Corrado Negro
OBJECTIVES: Malignant mesothelioma is closely associated to asbestos exposure. One such exposure may occur through contact with occupationally exposed household members and their belongings. This study examines the features of pleural mesothelioma attributable only to asbestos brought home by another family member. MATERIAL AND METHODS: The data sources were 1063 mesothelioma cases diagnosed between 1995 and 2014, from the Friuli Venezia Giulia Mesothelioma Register...
May 8, 2017: International Journal of Occupational Medicine and Environmental Health
https://www.readbyqxmd.com/read/28409857/asbestos-asbestosis-and-cancer-the-helsinki-criteria-for-diagnosis-and-attribution-critical-need-for-revision-of-the-2014-update
#5
Xaver Baur, Hans-Joachim Woitowitz, Lygia T Budnik, David Egilman, Christine Oliver, Arthur Frank, Colin L Soskolne, Philip J Landrigan, Richard A Lemen
No abstract text is available yet for this article.
May 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/28351840/macrophages-utilize-the-mitochondrial-calcium-uniporter-for-profibrotic-polarization
#6
Linlin Gu, Jennifer L Larson-Casey, A Brent Carter
Fibrosis in multiple organs, including the liver, kidney, and lung, often occurs secondary to environmental exposure. Asbestos exposure is one important environmental cause of lung fibrosis. The mechanisms that mediate fibrosis is not fully understood, although mitochondrial oxidative stress in alveolar macrophages is critical for fibrosis development. Mitochondrial Ca(2+) levels can be associated with production of reactive oxygen species. Here, we show that patients with asbestosis have higher levels of mitochondrial Ca(2+) compared with normal patients...
March 28, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28348451/serum-hmgb1-as-a-potential-biomarker-for-patients-with-asbestos-related-diseases
#7
Shibo Ying, Zhaoqiang Jiang, Xianglei He, Min Yu, Riping Chen, Junqiang Chen, Guoqing Ru, Yuan Chen, Wanyuan Chen, Lijin Zhu, Tao Li, Yixiao Zhang, Xinnian Guo, Xianhong Yin, Xing Zhang, Jianlin Lou
High-mobility group box 1 (HMGB1) functions as a proinflammatory cytokine and is one of the most intriguing molecules in inflammatory disorders and cancers. Notably, HMGB1 is a potential therapeutic target and novel biomarker in related diseases. However, the diagnostic value of HMGB1 for benign and malignant asbestos-related diseases (ARDs) remains unclear. In this work, we detected preoperative serum HMGB1 levels in Chinese asbestos-exposed (AE) and ARDs populations and further evaluated the diagnostic value of HMGB1 in patients with certain types of ARDs, including those with pleural plaques, asbestosis, or malignant mesothelioma (MM)...
2017: Disease Markers
https://www.readbyqxmd.com/read/28345684/-analysis-of-changes-in-radiographic-lung-image-and-lung-ventilation-disorders-in-workers-occupationally-exposed-to-chrysotile-in-the-past
#8
Elżbieta Cwynar, Beata Świątkowska, Jarosław Tomczyk
BACKGROUND: The adverse health effects of occupational exposure to asbestos dust may occur several years after first exposure. The objective of the study was to assess the relationship between lesions in the respiratory system and the factors contributing to occupational exposure to asbestos described in the first medical examination as well as to analyze the factors responsible for the progression of these changes in further medical tests. MATERIAL AND METHODS: The study group comprised 591 former workers of asbestos processing plant "Gambit" in Lubawka...
March 24, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28339055/new-insights-on-old-toxicants-in-occupational-toxicology-review
#9
Chiara Costa, Edoardo Miozzi, Michele Teodoro, Giusi Briguglio, Venerando Rapisarda, Concettina Fenga
In order to deliver the best possible working environment, it is essential to identify professional conditions that could be harmful for worker's health and prevent (or limit) the occurrence of such conditions. The appropriate use of personal protective equipment and the development of appropriate regulations allowed to reduce the prevalence of 'classic' occupational diseases, such as occupational hearing loss or asbestosis, just to name a few. Nowadays, environmental pollution seems to be one of the most relevant concerns for human and animal health, and toxicology is becoming one of the most prominent fields of interest in occupational settings...
May 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28258190/sirt3-deficiency-promotes-lung-fibrosis-by-augmenting-alveolar-epithelial-cell-mitochondrial-dna-damage-and-apoptosis
#10
Renea P Jablonski, Seok-Jo Kim, Paul Cheresh, David B Williams, Luisa Morales-Nebreda, Yuan Cheng, Anjana Yeldandi, Sangeeta Bhorade, Annie Pardo, Moises Selman, Karen Ridge, David Gius, G R Scott Budinger, David W Kamp
Alveolar epithelial cell (AEC) mitochondrial dysfunction and apoptosis are important in idiopathic pulmonary fibrosis and asbestosis. Sirtuin 3 (SIRT3) detoxifies mitochondrial reactive oxygen species, in part, by deacetylating manganese superoxide dismutase (MnSOD) and mitochondrial 8-oxoguanine DNA glycosylase. We reasoned that SIRT3 deficiency occurs in fibrotic lungs and thereby augments AEC mtDNA damage and apoptosis. Human lungs were assessed by using immunohistochemistry for SIRT3 activity via acetylated MnSOD(K68) Murine AEC SIRT3 and cleaved caspase-9 (CC-9) expression were assayed by immunoblotting with or without SIRT3 enforced expression or silencing...
March 3, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28213592/the-evidence-of-benefits-of-exercise-training-in-interstitial-lung-disease-a-randomised-controlled-trial
#11
Leona M Dowman, Christine F McDonald, Catherine J Hill, Annemarie L Lee, Kathryn Barker, Claire Boote, Ian Glaspole, Nicole S L Goh, Anne M Southcott, Angela T Burge, Rebecca Gillies, Alicia Martin, Anne E Holland
BACKGROUND: Uncertainty exists regarding the clinical relevance of exercise training across the range of interstitial lung diseases (ILDs). OBJECTIVE: To establish the impact of exercise training in patients with ILDs of differing aetiology and severity. METHODS: 142 participants with ILD (61 idiopathic pulmonary fibrosis (IPF), 22 asbestosis, 23 connective tissue disease-related ILD (CTD-ILD) and 36 with other aetiologies) were randomised to either 8 weeks of supervised exercise training or usual care...
February 17, 2017: Thorax
https://www.readbyqxmd.com/read/28194083/asbestos-induced-lung-disease-in-small-scale-clutch-manufacturing-workers
#12
Dipti Gothi, Tanushree Gahlot, Ram B Sah, Mayank Saxena, U C Ojha, Anand K Verma, Sonam Spalgais
BACKGROUND: The crocidolite variety of asbestos is banned. However, chrysotile, which is not prohibited, is still used in developing countries in making products such as clutch plate. Fourteen workers from a small-scale clutch plate-manufacturing factory were analyzed for asbestos-induced lung disease as one of their colleagues had expired due to asbestosis. AIMS: This study was conducted to evaluate the awareness of workers, the prevalence and type of asbestos-induced lung disease, and the sensitivity and specificity of diffusion test...
May 2016: Indian Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28162043/chest-ultrasonography-in-health-surveillance-of-asbestos-related-lung-diseases
#13
Andrea Smargiassi, Giuliana Pasciuto, Ilaria Pedicelli, Erminia Lo Greco, Mariarosaria Calvello, Riccardo Inchingolo, Gioacchino Schifino, Patrizio Capoluongo, Pasquale Patriciello, Maurizio Manno, Alfonso Cirillo, Giuseppe Maria Corbo, Gino Soldati, Ivo Iavicoli
OBJECTIVES: Exposure to asbestos fibers can lead to different lung diseases, such as pleural thickening and effusion, asbestosis, mesothelioma, and lung cancer. These diseases are expected to peak in the next few years. The aim of the study was to validate ultrasonography (US) as a diagnostic tool in the management of lung diseases in subjects with a history of occupational exposure to asbestos. METHODS: Fifty-nine retired male workers previously exposed to asbestos were enrolled in the study...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28002541/distinction-between-mesothelioma-and-lung-adenocarcinoma-based-on-immunohistochemistry-in-a-patient-with-asbestos-bodies-in-bronchoalveolar-fluid-case-report
#14
Agripina Raşcu, Eugenia Naghi, Marina Ruxandra OŢelea, Floarea Mimi NiŢu, Oana Cristina Arghir
Asbestos is a mineral-mined form the rocks, consisting in amosite (brown asbestos), crocidolite (blue asbestos) and÷or chrysotile (white asbestos) used in many industries. Researches about the exposure to asbestos dust and asbestosis related diseases started almost a century ago. The first case report of fatal asbestosis disease was published in 1906, in England, by Dr. Hubert Montague Murray. A decade after, asbestos "curious bodies" were firstly described in the lung tissue by Cooke (1926) and McDonald (1927)...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27866549/-characteristics-of-lung-function-in-patients-with-asbestosis-of-different-stages
#15
X L Yang, X L Zhu, A Li, X Q Du, Y G Song, Q Ye
Objective: To investigate the characteristics of lung function in the patients with asbestosis of different stages, and analyze the correlations between the pulmonary function values and imaging score of chest X-ray. Methods: A cohort of newly diagnosed 249 asbestosis patients over a period of eight years in a single center were evaluated. Clinical data were collected from clinical charts. Radiographs were reviewed by the experts blinded to clinical data. The asbestosis patients were classified into I to III stages by chest X-ray according to the guideline...
September 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/27781966/-financial-compensation-for-asbestosis-patients
#16
W Hagmolen Of Ten Have, J M Rooijackers, J A Burgers
Asbestosis in the Netherlands is a rare work-related form of pulmonary fibrosis caused by long-term, intensive exposure to asbestos. It can have a great impact on patients' quality of life and life expectancy even 20-30 years after initial exposure. The Dutch Institute of Asbestos Victims (IAS) mediates between the victims and their employers or former employers about payment of compensation. Liability procedures against a previous employer are long and stressful. Since 1 April 2014 it has, therefore, been possible to receive financial aid from the state...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27705550/tyler-asbestos-workers-a-mortality-update-in-a-cohort-exposed-to-amosite
#17
Jeffrey L Levin, Alina Rouk, Sara Shepherd, George A Hurst, Jerry W McLarty
The Tyler asbestos plant produced pipe insulation from 1954 to 1972 and exclusively used amosite asbestos. There were 1130 former workers of this plant during the period of operation. A death certificate mortality analysis was published regarding this plant in 1998 for the period through 1993. This study represents an update of the mortality analysis with additional certificates collected for deaths occurring through 2011.Searches of the National Death Index database were conducted in 2004 and again in 2013...
2016: Journal of Toxicology and Environmental Health. Part B, Critical Reviews
https://www.readbyqxmd.com/read/27650313/the-nlrp3-inflammasome-in-pathogenic-particle-and-fibre-associated-lung-inflammation-and-diseases
#18
REVIEW
Mutlay Sayan, Brooke T Mossman
The concept of the inflammasome, a macromolecular complex sensing cell stress or danger signals and initiating inflammation, was first introduced approximately a decade ago. Priming and activation of these intracellular protein platforms trigger the maturation of pro-inflammatory chemokines and cytokines, most notably, interleukin-1β (IL-1β) and IL-18, to promulgate innate immune defenses. Although classically studied in models of gout, Type II diabetes, Alzheimer's disease, and multiple sclerosis, the importance and mechanisms of action of inflammasome priming and activation have recently been elucidated in cells of the respiratory tract where they modulate the responses to a number of inhaled pathogenic particles and fibres...
September 20, 2016: Particle and Fibre Toxicology
https://www.readbyqxmd.com/read/27587956/radiologic-diagnosis-of-asbestosis-in-korea
#19
REVIEW
Yoon Ki Cha, Jeung Sook Kim, Yookyung Kim, Yoon Kyung Kim
Asbestosis is the most important change noted in the lung parenchyma after environmental and occupational exposure to asbestos fibers. It is characterized by diffuse interstitial pulmonary fibrosis. In Korea, the incidence of asbestosis will continue to increase for many years to come and the government enacted the Asbestos Damage Relief Law in 2011 to provide compensation to those suffering from asbestos-related diseases. Radiologic evaluation is necessary for diagnosis of asbestosis, and radiologists play a key role in this process...
September 2016: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/27575267/pathology-of-asbestosis-an-update-of-the-diagnostic-criteria-response-to-a-critique
#20
Victor Roggli, Allen R Gibbs, Richard Attanoos, Andrew Churg, Helmut Popper, Bryan Corrin, Teri Franks, Françoise Galateau-Salle, Jeff Galvin, Philip Hasleton, Koichi Honma
No abstract text is available yet for this article.
September 2016: Archives of Pathology & Laboratory Medicine
keyword
keyword
26488
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"