keyword
https://read.qxmd.com/read/38436809/low-serum-total-cholesterol-levels-predict-inferior-prognosis-of-patients-with-poems-syndrome
#1
JOURNAL ARTICLE
Jue Zhang, Ting Zhang, Ye Yao, Xuxing Shen, Yuanyuan Jin, Run Zhang, Lijuan Chen
Low serum cholesterol levels are associated with increased tumor morbidity and mortality. However, the relationship between serum lipid profile and POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes) is still unclear. The aim of our study was to clarify the importance of the serum lipid profile in predicting the severity and prognosis of patients with POEMS syndrome. Forty-three patients with newly diagnosed POEMS syndrome admitted to the Department of Hematology of Jiangsu Provincial People's Hospital between August 2013 and February 2023 were selected...
March 4, 2024: Discover. Oncology
https://read.qxmd.com/read/38435320/calciphylaxis-in-poems-syndrome-case-report
#2
JOURNAL ARTICLE
Danica Novacic, Thomas Uldrick, Alina Dulau-Florea, Colleen Evans Howe, Chyi-Chia R Lee, Heidi H Kong, William A Gahl
POEMS Syndrome is a constellation of findings including Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal plasma cell disorder, and Skin changes. Calciphylaxis, a microangiopathy involving vascular calcification and thrombotic occlusions, occurs rarely in POEMS. We present a case of prominent calciphylaxis that antedated the diagnosis of POEMS. The patient presented with extensive ecchymoses progressing to necrotic lesions in the setting of acute renal injury. Previously, she had chronic slowly progressive polyneuropathy, splenomegaly, hypothyroidism, amenorrhea, and ascites...
2024: Rare
https://read.qxmd.com/read/38428848/a-case-of-poems-syndrome-comprising-of-a-complicated-diagnostic-procedure-case-report
#3
REVIEW
Hai-Ping Huang, Hong-Mei Ran, Zheng-Sheng Li, Juan Xie
RATIONALE: This article presents the case of a patient with recurrent chronic diarrhea and cachexia who was misdiagnosed, followed by a literature review to summarize the reasons for misdiagnosis of POEMS syndrome and the treatment strategies. PATIENT CONCERNS: The diagnosis and treatment of this patient suggest that with the improvement of M-protein detection levels, the diagnosis of patients with low M-protein levels, such as those with POEMS syndrome, has been greatly aided...
March 1, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38411683/-top-4-research-studies-of-the-month-for-italian-primary-care-physicians-february-2024
#4
JOURNAL ARTICLE
Peter K Kurotschka, Alice Serafini, Mark H Ebell
This monthly article provides a collection of summaries of the most relevant studies identified as POEMs (patient-oriented evidence that matters) for Italian primary care physicians. 1) For patients with severe fatigue at least 3 months after Covid-19 infection, cognitive behavioral therapy offers significant improvement in symptoms over care as usual. 2) Key changes in the US chronic coronary disease guideline recommendations include the following. Shortening the duration of dual antiplatelet therapy, the use of beta-blockers in patients with chronic coronary disease, not recommending fish oil or omega-3 fatty acids for secondary prevention, not using e-cigarettes as first-line agents (but as secondary agents) for smoking cessation, and incorporating sodium-glucose transport protein 2 inhibitors (Sglt-2i) and glucagon-like peptide-1 (GLP-1) receptor agonists for some patients with chronic coronary disease, including those without comorbid diabetes mellitus...
March 2024: Recenti Progressi in Medicina
https://read.qxmd.com/read/38394381/a-poetic-inquiry-the-role-of-the-social-sciences-and-humanities-in-revitalising-aids
#5
JOURNAL ARTICLE
Heidi van Rooyen
For the past four decades, biomedical science has transformed clinical outcomes for HIV and AIDS. However, the social, economic and gendered determinants of HIV remain largely intact. The social science and humanities offer concepts and methods for articulating why these remain intractable. I used poetic inquiry - an arts-based, qualitative approach - as I reviewed literature on the "end of AIDS, and post-AIDS". As I did so, I considered what contribution the social sciences and humanities could make in moving us closer to these ideals...
February 23, 2024: AIDS Care
https://read.qxmd.com/read/38322456/polyneuropathy-organomegaly-endocrinopathy-m-protein-skin-changes-syndrome-with-dilated-cardiomyopathy-a-case-report
#6
Jia-Rong Li, Lei-Yu Feng, Jian-Wei Li, Yu Liao, Fei-Qi Liu
BACKGROUND: Polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes (POEMS) syndrome is a rare paraneoplastic syndrome that encompass multiple systems. The most common clinical symptoms of POEMS syndrome are progressive sensorimotor polyneuropathy, organ enlargement, endocrine disorders, darkening skin, a monoclonal plasma cell proliferative disorder, and lymph node hyperplasia. The organomegaly consists of hepatosplenomegaly and/or lymphadenopathy; cases of cardiomyopathy are rare...
January 26, 2024: World Journal of Clinical Cases
https://read.qxmd.com/read/38288324/efficacy-of-bortezomib-cyclophosphamide-and-dexamethasone-for-newly-diagnosed-poems-syndrome-patients
#7
JOURNAL ARTICLE
Fang Fang, Xiao-Xi Lan, Rong-Hua Hu, Wu-Han Hui, Hong Zhao, Yi-Xian Guo, Bing-Xin Ji, Hong-Jun Liu, Li Su, Wan-Ling Sun
BACKGROUND: Due to the rarity of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome, the best first-line treatment has not been established, although there are several options in guidelines. The preferred treatments vary according to the preference of the physician and anecdote. OBJECTIVES: First, to analyze the efficacy of a new treatment mode in POEMS syndrome that uses the four-cycle treatment as the induction regimen, followed by sequential transplantation as the consolidation regimen for transplantation-eligible patients, or received another two-cycle treatment for transplantation-ineligible patients...
2024: Therapeutic Advances in Neurological Disorders
https://read.qxmd.com/read/38283273/from-hepatomegaly-to-poems-syndrome-a-case-report
#8
Yavuz Ozden, Sebnem Gursoy
We present a case of POEMS syndrome from Turkiye, a rare, multisystemic condition resulting from plasma cell dyscrasia. POEMS is an acronym representing its cardinal features: Peripheral neuropathy; Organomegaly; Endocrinopathy; Monoclonal plasma-cell proliferative disorder; and Skin changes. The syndrome has an estimated prevalence of 0.3 per 100,000 individuals and typically manifests in the fifth or sixth decade of life. Progressive peripheral neuropathy is the syndrome's most prominent symptom. To ensure an accurate diagnosis, a thorough medical history, physical examination, and comprehensive diagnostic evaluations are essential...
2024: Hepatol Forum
https://read.qxmd.com/read/38225781/a-multicenter-analysis-of-clinical-features-and-long-term-outcomes-of-poems-syndrome-in-korea
#9
MULTICENTER STUDY
Hye Won Kook, Ji Eun Jang, Chang-Ki Min, Dok Hyun Yoon, Kihyun Kim, Soo-Mee Bang, Yong Park, Jae Hoon Lee, Sung-Soo Yoon, Jin Seok Kim
BACKGROUND: POEMS syndrome is a rare form of plasma cell dyscrasia characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal proteins, and skin changes. Owing to its low incidence, there are few reports regarding this syndrome. This multicenter study included 84 patients diagnosed with POEMS syndrome in South Korea. METHODS: We retrospectively evaluated 84 patients diagnosed with POEMS syndrome at 8 hospitals in South Korea between January 2000 and October 2022...
January 15, 2024: Journal of Korean Medical Science
https://read.qxmd.com/read/38148011/clinico-pathological-profile-of-patients-with-plasma-cell-neoplasms-with-special-reference-to-bone-marrow-fibrosis-and-amyloid-deposition
#10
JOURNAL ARTICLE
Narasimhapriyan Kannan, Jasmita Dass, Sahitya Dangudubiyyam, Ganesh Kumar Viswanathan, Mukul Aggarwal, Pradeep Kumar, Rishi Dhawan, Tulika Seth, Manoranjan Mahapatra
To clarify the significance of bone marrow fibrosis and amyloid deposition in plasma cell neoplasm, a retrospective cross-sectional study for a period of 3 years was conducted. Patients who underwent bone marrow aspiration and biopsy with suspicion of plasma cell neoplasms were included in the study. The bone marrow findings were correlated with clinical profile of the patient along with biochemical parameters, cytogenetics, Fluorescent in situ hybridization (FISH) wherever available. A total of 273 bone marrow aspirates and biopsies of patients with suspected plasma cell neoplasms were analyzed...
2023: Journal of Clinical and Experimental Hematopathology: JCEH
https://read.qxmd.com/read/38143657/poems-polyneuropathy-organomegaly-endocrinopathy-monoclonal-plasma-cell-disorder-and-skin-changes-syndrome-as-a-sequela-of-castleman-disease-a-case-report
#11
Syed Abdullah Haider, Sadia Iram, Asma Abdul Rashid, Anusha Manazar, Hamza Javed
Polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes (POEMS) syndrome is a rare multisystemic paraneoplastic disorder caused by an underlying plasma cell dyscrasia. Its diagnosis is based on the presence of two mandatory criteria and at least one major and one minor criterion. We report a case of a 52-year-old female patient who presented with complaints of acrocyanosis, night sweats, scaly skin, and swelling on the left side of the neck. She was a known case of hypothyroidism, antiphospholipid syndrome, and cerebral venous thrombosis, and had other comorbidities as well...
November 2023: Curēus
https://read.qxmd.com/read/38115326/poems-syndrome-characterized-by-bone-lesions-a-case-report
#12
JOURNAL ARTICLE
Yang Wang, Yalong Liu, Xiaoli Huang, Lan Peng, Zhijun Zhang
RATIONALE: POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal paraproteinemia, and skin changes) syndrome is a rare clinical syndrome characterized by multiple peripheral neuropathies, hepatosplenomegaly, endocrine disorders, monoclonal paraproteinemia, and dermatosis. The main manifestations of POMES were nerve and skin changes, and bone disease was not reported. Here, we report a case of POEMS syndrome with the main manifestation of bone lesions. PATIENT CONCERNS: POMES is rare and its clinical manifestations are complex, making it difficult for patients to find the department they should visit...
December 15, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/38082007/robotic-heller-s-myotomy-using-the-new-hugo%C3%A2-ras-system-first-worldwide-report
#13
JOURNAL ARTICLE
Samer Abu Salem, Gad Marom, Gabriel Szydlo Shein, Yuri Fishman, Brigitte Helou, Ronit Brodie, Ram Elazary, Alon J Pikarsky, Yoav Mintz
BACKGROUND: Achalasia is a rare disorder of the esophagus characterized by motor dysfunction in the esophagus and relaxation failure of the lower esophageal sphincter (LES). Currently, surgical myotomy procedures are considered the standard of care. Robotic Heller's myotomy (RHM) with fundoplication has been gaining popularity due to documented advantages in the precision of myotomy as well as avoiding the potential reflux following per-oral endoscopic myotomy (POEM). To the best of our knowledge, RHM has thus far has been performed exclusively by the da Vinci surgical system...
December 11, 2023: Surgical Endoscopy
https://read.qxmd.com/read/38070692/an-unusual-cause-of-ascites-in-a-patient-with-hepatitis-b
#14
JOURNAL ARTICLE
Liling Lai, Chunyan Rao, Huabao Liu
No abstract text is available yet for this article.
December 7, 2023: Gastroenterology
https://read.qxmd.com/read/37993859/pulmonary-manifestations-of-poem-syndrome-a-retrospective-analysis-of-282-cases
#15
JOURNAL ARTICLE
Yilin Huang, Yang Luo, Huan Hou, Jinming Gao
BACKGROUND: Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome is a rare multisystemic clonal plasma cell disorder. Pulmonary involvement is frequently found in patients with POEMS syndrome, manifesting various clinical features. Therefore, to improve diagnostic accuracy and provide treatment strategies, a comprehensive analysis of pulmonary manifestations of POEMS syndrome is needed. METHODS: This retrospective study included patients with POEMS syndrome at Peking Union Medical College Hospital, a major referral medical center in China, between June 1, 2013, and June 1, 2023...
November 23, 2023: BMC Pulmonary Medicine
https://read.qxmd.com/read/37987277/unraveling-the-neurological-complexity-of-polyneuropathy-organomegaly-endocrinopathy-monoclonal-protein-and-skin-changes-syndrome-a-report-of-a-challenging-case-of-a-young-woman-and-cutting-edge-advancements-in-the-field
#16
Gioconda Furciniti, Giuseppe Casalino, Francesco M Lo Russo, Niccolò Bolli, Megi Meneri, Giacomo P Comi, Stefania P Corti, Daniele Velardo
POEMS syndrome-characterized by polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes-is an uncommon and complex paraneoplastic disorder encompassing a diverse array of symptoms. Here we report the challenging case of a 34-year-old female who sought medical attention at the emergency department due to distal lower limb weakness. She was breastfeeding her first child at that time. Her condition rapidly deteriorated, making it difficult for her to perform simple tasks independently. Initially, she struggled with activities like jumping or climbing stairs...
November 10, 2023: Diseases (Basel)
https://read.qxmd.com/read/37982467/concomitant-aesop-and-poems-syndrome-in-the-context-of-osseous-and-cutaneous-plasmacytomas-answer
#17
JOURNAL ARTICLE
Nada Shaker, Omar P Sangueza
No abstract text is available yet for this article.
December 1, 2023: American Journal of Dermatopathology
https://read.qxmd.com/read/37931801/long-term-outcomes-of-autologous-stem-cell-transplantation-in-patients-with-newly-diagnosed-poems-syndrome
#18
JOURNAL ARTICLE
An-An Li, Xue-Min Gao, Hao Zhao, Kai-Ni Shen, Lu Zhang, Xin-Xin Cao, Jian Li
BACKGROUND: POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes) syndrome is a rare form of plasma cell dyscrasia often treated with high-dose chemotherapy and autologous stem cell transplantation (ASCT). ASCT has resulted in satisfactory and sustained therapeutic outcomes. However, a substantial number of patients eventually experience disease progression, requiring second-line treatment. Therefore, it would be of further benefit to identify patients who will acquire the best long-term survival after ASCT...
November 4, 2023: Transplantation and cellular therapy
https://read.qxmd.com/read/37916657/giant-papillary-hemangioma-a-rare-tumor-with-an-exceptional-size
#19
Maryam Abdo, Jordan A Dykstra, Anders Meyer, Hongyan Dai
Papillary hemangioma (PH) is a recently described vascular tumor with a predilection for the skin of the head and neck. Histopathologically, it is characterized by a bland endothelial proliferation arranged in a papillary configuration, bearing resemblance to glomeruloid hemangioma seen in the context of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes syndrome. The largest cutaneous PH reported to date measured 1.5 cm in greatest dimension. Here, we report a case of PH with an alarming size of 10 cm...
November 2, 2023: Journal of Cutaneous Pathology
https://read.qxmd.com/read/37842561/poems-syndrome-in-the-21st-century-a-bibliometric-analysis
#20
JOURNAL ARTICLE
Fangrong Zhang, Zhimin Wu, Shanyi Sun, Yunfeng Fu, Yi Chen, Jing Liu
BACKGROUND: POEMS syndrome is a rare and complex plasma cell disorder characterized by polyneuropathy, organomegaly, endocrinopathy, high M protein levels, and skin changes. Understanding of POEMS syndrome has advanced rapidly since the 21st century. This study aims to summarize and evaluate the research status of POEMS syndrome in the past 23 years through a bibliometric and visualization analysis, and identify research focuses and emerging hotspots for the future. METHODS: POEMS syndrome-related articles published between January 1, 2000, and March 8, 2023, were systematically retrieved from the Web of Science Core Collection...
October 2023: Heliyon
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