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https://www.readbyqxmd.com/read/28107164/decreasing-human-trafficking-through-sex-work-decriminalization
#1
Erin Albright, Kate D'Adamo
In order to decrease human trafficking, health care workers should support the full decriminalization of prostitution. Similar to trafficking in other forms of labor, preventing trafficking in the sex trade requires addressing the different forms of marginalization that create vulnerable communities. By removing punitive laws that prevent reporting of exploitation and abuse, decriminalization allows sex workers to work more safely, thereby reducing marginalization and vulnerability. Decriminalization can also help destigmatize sex work and help resist political, social, and cultural marginalization of sex workers...
January 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/28104789/a-novel-humanized-mouse-model-of-huntington-disease-for-preclinical-development-of-therapeutics-targeting-mutant-huntingtin-alleles
#2
Amber L Southwell, Niels H Skotte, Erika B Villanueva, Michael E Østergaard, Xiaofeng Gu, Holly B Kordasiewicz, Chris Kay, Daphne Cheung, Yuanyun Xie, Sabine Waltl, Louisa Dal Cengio, Hailey Findlay-Black, Crystal N Doty, Eugenia Petoukhov, Diepiriye Iworima, Ramy Slama, Jolene Ooi, Mahmoud A Pouladi, William X Yang, Eric E Swayze, Punit P Seth, Michael R Hayden
Huntington disease (HD) is a neurodegenerative disease caused by a mutation in the huntingtin (HTT) gene. HTT is a large protein, interacts with many partners and is involved in many cellular pathways, which are perturbed in HD. Therapies targeting HTT directly are likely to provide the most global benefit. Thus there is a need for preclinical models of HD recapitulating human HTT genetics. We previously generated a humanized mouse model of HD, Hu97/18, by intercrossing BACHD and YAC18 mice with knockout of the endogenous mouse HD homolog (Hdh)...
January 18, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28102544/nursing-perceptions-of-patient-safety-climate-in-the-gaza-strip-palestine
#3
A Elsous, A Akbari Sari, Y AlJeesh, M Radwan
AIMS: This study was undertaken to assess the perception of nurses about patient safety culture and to test whether it is significantly affected by the nurses' position, age, experience and working hours. BACKGROUND: Patient safety has sparked the interest of healthcare mangers, yet there is limited knowledge about the current patient safety culture among nurses in the Gaza Strip. METHODS: This was a descriptive cross-sectional study, administering the Arabic Safety Attitude Questionnaire (Short Form 2006) to 210 nurses in four public general hospitals...
January 19, 2017: International Nursing Review
https://www.readbyqxmd.com/read/28100098/analyzing-further-predictors-of-correctional-officer-professional-orientations
#4
Frank Valentino Ferdik, Phillip Hills
Four professional orientations to which correctional officers can ascribe have been identified in extant literature, and they include the counseling roles, concern for corruption of authority, social distance, and punitive ideologies. Studies have generally found officer demographics and correctional working conditions to be significant predictors of these orientations. No study to date, however, has examined the predictive influence of officer voluntary resignation intentions. Linear regression equations using questionnaire data from a statewide population of maximum security correctional officers ( N = 649) were therefore estimated to explore whether officer desires to terminate their employment accounted for variance in their self-reported orientations...
January 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/28088096/mycelium-transformation-of-streptomyces-toxytricini-into-pellet-role-of-culture-conditions-and-kinetics
#5
Punit Kumar, Kashyap Kumar Dubey
The present study envisages the role of different carbon sources, nitrogen sources, metals, pH, inoculum volume and agitation rate in pellet formation of S. toxytricini at shake-flask level. It was found that galactose, ammonium sulphate, sodium nitrate, Cu(2+), Zn(2+), higher inoculum volume (5% v/v) and agitation rate at 300rpm caused significant reduction in pellet size (up to the range of 30μm-0.5mm) but biomass formations was also reduced subsequently. Interestingly diffused type of morphology was obtained in Fe(2+) supplemented medium with reduced biomass (1...
January 6, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28087116/application-of-whole-exome-sequencing-in-elucidating-the-phenotype-and-genotype-spectrum-of-junctional-epidermolysis-bullosa-a-preliminary-experience-of-a-tertiary-care-centre-in-india
#6
Vamsi K Yenamandra, Shamsudheen K Vellarikkal, Manoj Kumar, Madhumita R Chowdhury, Rijith Jayarajan, Ankit Verma, Vinod Scaria, Sridhar Sivasubbu, Subrata B Ray, Amit K Dinda, Madhulika Kabra, Punit Kaur, Vinod K Sharma, Gomathy Sethuraman
BACKGROUND: Junctional epidermolysis bullosa (JEB) is a diverse group of genodermatoses associated with extreme skin fragility. Despite several well-characterized genetic studies, molecular diagnosis of this heterogeneous group is still challenging. Recent advances in the field of genomics have seen the successful implementation of whole exome sequencing (WES) as a fast and efficient diagnostic strategy in several genodermatoses. OBJECTIVE: In view of the scarcity and need of molecular studies for JEB in India, we sought to explore the potential of WES in understanding the mutational spectrum of this rare, in certain subtypes lethal, sub-group of EB...
December 29, 2016: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28076976/measuring-parenting-throughout-adolescence
#7
Martijn Van Heel, Patricia Bijttebier, Stephan Claes, Hilde Colpin, Luc Goossens, Wim Van Den Noortgate, Karine Verschueren, Karla Van Leeuwen
This study examined the structural validity of the parenting concept throughout adolescence. First, we examined whether an established five-dimension parenting model including support, proactive control, punitive control, harsh punitive control, and psychological control, showed longitudinal invariance across time (i.e., early, middle, and late adolescence) and measurement invariance across informants (i.e., mothers, fathers, and adolescents). Second, patterns of continuity and discontinuity in these dimensions were examined from the perspective of the different informants...
January 1, 2017: Assessment
https://www.readbyqxmd.com/read/28073997/beyond-ageist-attitudes-researchers-call-for-nih-action-to-limit-funding-for-older-academics
#8
Eva Kahana, Michael R Slone, Boaz Kahana, Kaitlyn Barnes Langendoerfer, Courtney Reynolds
PURPOSE: This article explores manifestations of ageism in response to a proposed National Institutes of Health (NIH) Emeritus Grant initiative aimed at funding older investigators. DESIGN AND METHODS: Comments were requested by NIH in 2015, through a Request for Information (RFI) as well as a public blog regarding the merits of a proposed grant mechanism that would help older researchers transfer their labs to junior scientists and transition into retirement. This article reports content analysis of comments from 134 respondents to the blog...
January 9, 2017: Gerontologist
https://www.readbyqxmd.com/read/28073903/assessing-patient-safety-culture-in-tunisian-operating-rooms-a-multicenter-study
#9
Manel Mallouli, Mohamed Ayoub Tlili, Wiem Aouicha, Mohamed Ben Rejeb, Chekib Zedini, Amrani Salwa, Ali Mtiraoui, Mohamed Ben Dhiab, Thouraya Ajmi
OBJECTIVE: To assess the patient safety culture (PSC) in operating rooms (ORs) and to determine influencing factors. DESIGN: A cross-sectional descriptive multicenter study which was conducted over a period of 7 months (October 2014-April 2015) using the French validated version of the Hospital Survey On Patient Safety Culture questionnaire. SETTING: Of the note, 15 ORs of public and private healthcare institutions. PARTICIPANTS: In total, there were 368 participants including surgeons, anesthesiologists, surgical and anesthesia technicians, nurses and caregivers, divided into 316 professionals exercising in public sector and 52 working in private one...
January 9, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28051056/unusual-presentations-of-child-abuse-a-report-of-two-cases-and-the-role-of-imaging
#10
Olubukola Titilayo Abeni Omidiji, Omolola Mojisola Atalabi, Ogbeide Ejeordamen Evbuomwan, Francis Ikechukwu Okwuegbuna, Olugbenga Oluseyi
Insufficient attention has been paid to child abuse in Nigeria, where corporal punishment is still acceptable both at home and in the wider public including schools. This is notlimited to the parents; these punitive measures can also be undertaken by the extended family, caregivers, and neighbors. Mild to extreme force is allowed particularly when the crime involves tarnishing the family image. We hereby report two cases of extreme discipline that can be termed as a form of child abuse to draw the attention of clinicians and radiologists to other possible findings aside from those already reported in literature...
October 2016: African Journal of Paediatric Surgery: AJPS
https://www.readbyqxmd.com/read/28049468/mandatory-tb-notification-in-mysore-city-india-have-we-heard-the-private-practitioner-s-plea
#11
Sarabjit Singh Chadha, Sharath Burugina Nagaraja, Archana Trivedi, Sachi Satapathy, Devendrappa N M, Karuna Devi Sagili
BACKGROUND: The Government of India, made TB notification by private healthcare providers mandatory from May 2012 onwards. The National TB Programme developed a case based web based online reporting mechanism called NIKSHAY. However, the notification by private providers has been very low. We conducted the present study to determine the awareness, practice and anticipated enablers related to TB notification among private practitioners in Mysore city during 2014. METHODS: A cross-sectional study was conducted among private practitioners of Mysore city in south India...
January 3, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28045350/social-stigma-toward-persons-with-prescription-opioid-use-disorder-associations-with-public-support-for-punitive-and-public-health-oriented-policies
#12
Alene Kennedy-Hendricks, Colleen L Barry, Sarah E Gollust, Margaret E Ensminger, Margaret S Chisolm, Emma E McGinty
OBJECTIVE: Prescription opioid use disorder and overdose have emerged as significant public health challenges in the past 15 years. Little is known about public attitudes toward individuals who have developed a prescription opioid use disorder and whether these attitudes affect support for policy interventions. This study examined social stigma toward individuals with prescription opioid use disorder and tested whether stigma was associated with support for various policy interventions...
January 3, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28039684/patients-bill-of-rights-and-effective-factors-of-workplace-violence-against-female-nurses-on-duty-at-ilam-teaching-hospitals
#13
Ali-Ashraf Aivazi, Waleyeh Menati, Hamed Tavan, Sasan Navkhasi, Abuzar Mehrdadi
BACKGROUND: Workplace violence against female nurses is an increasing problem. In addition, recognition the rights of patients can reduce such violence against female nurses. Therefore, the aim of the current study was to investigate workplace violence against female nurses in respect with patients' bill of rights at two public hospitals of Ilam in 2012. METHODS: In a descriptive cross-sectional research, workplace violence against female nurses was studied. Data were gathered employing a researcher made questionnaire filled out by 106 female nurses...
January 1, 2017: Journal of Injury & Violence Research
https://www.readbyqxmd.com/read/28031080/the-interaction-between-monoamine-oxidase-a-and-punitive-discipline-in-the-development-of-antisocial-behavior-mediation-by-maladaptive-social-information-processing
#14
Chardée A Galán, Daniel Ewon Choe, Erika E Forbes, Daniel S Shaw
Previous studies demonstrate that boys' monoamine oxidase A (MAOA) genotype interacts with adverse rearing environments in early childhood, including punitive discipline, to predict later antisocial behavior. Yet the mechanisms by which MAOA and punitive parenting interact during childhood to amplify risk for antisocial behavior are not well understood. In the present study, hostile attributional bias and aggressive response generation during middle childhood, salient aspects of maladaptive social information processing, were tested as possible mediators of this relation in a sample of 187 low-income men followed prospectively from infancy into early adulthood...
December 29, 2016: Development and Psychopathology
https://www.readbyqxmd.com/read/28011159/the-impact-of-state-tort-reforms-on-imaging-utilization
#15
Suhui Li, Avi Dors, Darwyyn Deyo, Danny R Hughes
PURPOSE: Defensive medicine, broadly defined as medical practices that protect physicians from malpractice lawsuits without providing benefits to patients, can lead to wasteful use of health care resources and higher cost. Although physicians cite malpractice liability as an important factor driving their decisions to order imaging tests, little research has been done to examine the systematic impact of liability pressure on overall imaging. The authors examined the extent to which radiography use is influenced by malpractice liability pressure among office-based physicians...
December 20, 2016: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/27990743/punishment-of-minor-female-genital-ritual-procedures-is-the-perfect-the-enemy-of-the-good
#16
Allan J Jacobs, Kavita Shah Arora
Female genital alteration (FGA) is any cutting, removal or destruction of any part of the external female genitalia. Various FGA practices are common throughout the world. While most frequent in Africa and Asia, transglobal migration has brought ritual FGA to Western nations. All forms of FGA are generally considered undesirable for medical and ethical reasons when performed on minors. One ritual FGA procedure is the vulvar nick (VN). This is a small laceration to the vulva that does not cause morphological changes...
December 19, 2016: Developing World Bioethics
https://www.readbyqxmd.com/read/27988315/child-maltreatment-and-emotion-socialization-associations-with-executive-function-in-the-preschool-years
#17
Tracey Fay-Stammbach, David J Hawes, Pamela Meredith
This study examined executive function (EF) among preschoolers exposed to maltreatment, and tested whether caregiver practices related to emotion socialization (e.g., reactions to children's emotions; discussion of emotion) moderate the relationship between maltreatment and EF in this period. Participants were (n=107) children aged 4-5 years (M=4.75; SD=0.57; 39% female), with various levels of exposure to maltreatment. Using the Maltreatment Classification System, substantiated reports of maltreatment were coded to produce an index of the multiplicity of abuse subtypes to which children had been exposed...
December 15, 2016: Child Abuse & Neglect
https://www.readbyqxmd.com/read/27986533/structure-of-bovine-lactoperoxidase-with-a-partially-linked-heme-moiety-at-1-98%C3%A3-resolution
#18
Prashant K Singh, Harsh V Sirohi, Naseer Iqbal, Pragya Tiwari, Punit Kaur, Sujata Sharma, Tej P Singh
Lactoperoxidase (LPO) is a member of mammalian heme peroxidase superfamily whose other members are myeloperoxidase (MPO), eosinophil peroxidase (EPO) and thyroid peroxidase (TPO). In these enzymes, the heme moiety is linked to protein through two or three covalent bonds. In the mature LPO, the heme moiety is linked to protein through two ester bonds with highly conserved glutamate and aspartate residues. The previously reported structures of LPO have confirmed the formation of two covalent linkages involving Glu258 and Asp108 with 1-methyl and 5-methyl groups of pyrrole rings A and C respectively...
December 13, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27982393/the-culture-of-patient-safety-from-the-perspective-of-the-pediatric-emergency-nursing-team
#19
Taise Rocha Macedo, Patricia Kuerten Rocha, Andreia Tomazoni, Sabrina de Souza, Jane Cristina Anders, Karri Davis
OBJECTIVE: To identify the patient safety culture in pediatric emergencies from the perspective of the nursing team. METHOD: A quantitative, cross-sectional survey research study with a sample composed of 75 professionals of the nursing team. Data was collected between September and November 2014 in three Pediatric Emergency units by applying the Hospital Survey on Patient Safety Culture instrument. Data were submitted to descriptive analysis. RESULTS: Strong areas for patient safety were not found, with areas identified having potential being: Expectations and actions from supervisors/management to promote patient safety and teamwork...
September 2016: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/27968890/patient-physician-trust-in-china-a-workshop-summary
#20
Cheris S C Chan, Yu Cheng, Yali Cong, Zhizheng Du, Shanlian Hu, Amanda Kerrigan, Arthur Kleinman, Mengfeng Li, Benjamin Liebman, Yonghui Ma, Jing-Bao Nie, Daniel F C Tsai, Duujian Tsai, Joseph D Tucker, Lijie Wang, Bonnie Wong, William C W Wong, Zeping Xiao, Juncai Xu, Yunxiang Yan, Yang Yang, Daqing Zhang, Mingjie Zhao, Jianfeng Zhu, Wei Zhu
BACKGROUND: Patient-physician mistrust has become deeply embedded in medical clinics within a wide variety of settings, including many in China. The purpose of this research was to develop a series of actionable policy recommendations to rebuild patient-physician trust in China. METHODS: Our interdisciplinary group included experts in medicine, public health, philosophy, ethics, law, regulation, China studies, anthropology, sociology, and communications. Recommendations were identified by team members and presented at a two-day workshop at the Harvard Center, Shanghai, China...
October 2016: Lancet
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