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https://www.readbyqxmd.com/read/28227612/bed-based-instrumentation-for-unobtrusive-sleep-quality-assessment-in-severely-disabled-autistic-children
#1
Charles Carlson, Ahmad Suliman, Punit Prakash, David Thompson, Shangxian Wang, Bala Natarajan, Steve Warren, Charles Carlson, Ahmad Suliman, Punit Prakash, David Thompson, Shangxian Wang, Bala Natarajan, Steve Warren, Shangxian Wang, Punit Prakash, Bala Natarajan, David Thompson, Charles Carlson, Steve Warren, Ahmad Suliman
The relationship between sleep quality and daytime wellness and performance in severely disabled, autistic children is not well understood. While polysomnography and, more recently, actigraphy serve as means to obtain sleep assessment data from neurotypical children and adults, these techniques are not well-suited to severely autistic children. This paper presents recent progress on a bed sensor suite that can unobtrusively track physiological and behavioral parameters used to assess sleep quality. Electromechanical films and load cells provide data that yield heart rate, respiration rate, center of position, in-and-out-of-bed activity, and general movement, while thermocouples are used to detect bed-wetting events...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227153/design-projects-motivated-and-informed-by-the-needs-of-severely-disabled-autistic-children
#2
Steve Warren, Punit Prakash, David Thompson, Bala Natarajan, Charles Carlson, Kim Fowler, Ed Brokesh, Jack Xin, Wayne Piersel, Janine Kesterson, Steve Stoffregen, Steve Warren, Punit Prakash, David Thompson, Bala Natarajan, Charles Carlson, Kim Fowler, Ed Brokesh, Jack Xin, Wayne Piersel, Janine Kesterson, Steve Stoffregen, Janine Kesterson, Bala Natarajan, David Thompson, Steve Stoffregen, Steve Warren, Kim Fowler, Jack Xin, Punit Prakash, Charles Carlson, Wayne Piersel
Technology can positively impact the lives of severely disabled autistic children if used to (a) gather situational awareness data regarding their health, development, and behavior and (b) assist them with learning and day-to-day activities. This paper summarizes student design projects in the Kansas State University (KSU) College of Engineering that are motivated and informed by the needs of severely disabled children at Heartspring, Wichita, KS. These efforts are supported through the National Science Foundation's General and Age-Related Disabilities Engineering (GARDE) program...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28219965/a-public-health-response-to-opioid-use-in-pregnancy
#3
Stephen W Patrick, Davida M Schiff
The use of opioids during pregnancy has grown rapidly in the past decade. As opioid use during pregnancy increased, so did complications from their use, including neonatal abstinence syndrome. Several state governments responded to this increase by prosecuting and incarcerating pregnant women with substance use disorders; however, this approach has no proven benefits for maternal or infant health and may lead to avoidance of prenatal care and a decreased willingness to engage in substance use disorder treatment programs...
February 20, 2017: Pediatrics
https://www.readbyqxmd.com/read/28216710/anaesthesia-for-emergency-caesarean-section-in-a-morbidly-obese-achondroplastic-patient-with-pih-feasibility-of-neuraxial-anaesthesia
#4
Ridhima Sharma, Rohan Magoon, Ripon Choudhary, Punit Khanna
No abstract text is available yet for this article.
January 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28206830/medical-student-beliefs-about-disclosure-of-mental-health-issues-a-qualitative-study
#5
Peter Winter, Andrew Rix, Andrew Grant
In 2012 the United Kingdom's General Medical Council (GMC) commissioned research to develop guidance for medical schools on how best to support students with mental illness. One of the key findings from medical student focus groups in the study was students' strong belief that medical schools excluded students on mental health grounds. Students believed mental illness was a fitness to practice matter that led to eventual dismissal, although neither personal experience nor empirical evidence supported this belief...
2017: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/28198929/authoritarianism-and-punitive-eugenics-racial-hygiene-and-national-catholicism-during-francoism-1936-1945
#6
Ricardo Campos
This paper examines some of the main elements that shaped eugenic discourse and practices during the first decades of the Franco regime. It primarily addresses the ideological basis of racial hygiene stemming from Francoist medicine and psychiatry, examining its relationship with the concept of Spanishness (Hispanidad). It shows that Francoist eugenics had punitive and coercive aspects and outlines the role it played in the brutal repression unleashed against the regime's political enemies, constructing its anti-Spanish identity...
December 2016: História, Ciências, Saúde—Manguinhos
https://www.readbyqxmd.com/read/28190670/assessing-the-concordance-between-illicit-drug-laws-on-the-books-and-drug-law-enforcement-comparison-of-three-states-on-the-continuum-from-decriminalised-to-punitive
#7
Vendula Belackova, Alison Ritter, Marian Shanahan, Caitlin E Hughes
BACKGROUND: Variations in drug laws, as well as variations in enforcement practice, exist across jurisdictions. This study explored the feasibility of categorising drug laws "on the books" in terms of their punitiveness, and the extent of their concordance with "laws in practice" in a cross-national comparison. METHODS: "Laws on the books", classified with respect to both cannabis and other drug offences in the Czech Republic, NSW (AU) and Florida (USA) were analysed in order to establish an ordinal relationship between the three states...
February 9, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28184313/juvenile-delinquency-welfare-justice-and-therapeutic-interventions-a-global-perspective
#8
REVIEW
Susan Young, Ben Greer, Richard Church
This review considers juvenile delinquency and justice from an international perspective. Youth crime is a growing concern. Many young offenders are also victims with complex needs, leading to a public health approach that requires a balance of welfare and justice models. However, around the world there are variable and inadequate legal frameworks and a lack of a specialist workforce. The UK and other high-income countries worldwide have established forensic child and adolescent psychiatry, a multifaceted discipline incorporating legal, psychiatric and developmental fields...
February 2017: BJPsych Bulletin
https://www.readbyqxmd.com/read/28182459/deconstructing-the-simplification-of-jury-instructions-how-simplifying-the-features-of-complexity-affects-jurors-application-of-instructions
#9
Chantelle M Baguley, Blake M McKimmie, Barbara M Masser
Research consistently shows that techniques currently used to simplify jury instructions do not always improve mock jurors' comprehension. If improvements are observed, these are limited and overall comprehension remains low. It is unclear, however, why this occurs. It is possible that current simplification techniques do not effectively simplify the features of complexity, present in standardized instructions, which have the greatest effect on jurors' comprehension. It is not yet known, however, how much each feature of complexity individually affects jurors' comprehension...
February 9, 2017: Law and Human Behavior
https://www.readbyqxmd.com/read/28162960/antisense-reduction-of-mutant-comp-reduces-growth-plate-chondrocyte-pathology
#10
Karen L Posey, Francoise Coustry, Alka C Veerisetty, Mohammad Hossain, Danielle Gattis, Sheri Booten, Joseph L Alcorn, Punit P Seth, Jacqueline T Hecht
Mutations in cartilage oligomeric matrix protein cause pseudoachondroplasia, a severe disproportionate short stature disorder. Mutant cartilage oligomeric matrix protein produces massive intracellular retention of cartilage oligomeric matrix protein, stimulating ER and oxidative stresses and inflammation, culminating in post-natal loss of growth plate chondrocytes, which compromises linear bone growth. Treatments for pseudoachondroplasia are limited because cartilage is relatively avascular and considered inaccessible...
February 3, 2017: Molecular Therapy: the Journal of the American Society of Gene Therapy
https://www.readbyqxmd.com/read/28158620/characterizing-the-effect-of-galnac-and-phosphorothioate-backbone-on-binding-of-antisense-oligonucleotides-to-the-asialoglycoprotein-receptor
#11
Karsten Schmidt, Thazha P Prakash, Aaron J Donner, Garth A Kinberger, Hans J Gaus, Audrey Low, Michael E Østergaard, Melanie Bell, Eric E Swayze, Punit P Seth
No abstract text is available yet for this article.
February 3, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28155740/-patient-safety-culture-based-on-a-non-punitive-response-to-error-and-freedom-of-expression-of-healthcare-professionals
#12
Mohamed Mahjoub, Nabiha Bouafia, Asma Ben Cheikh, Olfa Ezzi, Mansour Njah
This study provided an overview of healthcare professionals’ perception of patient safety based on analysis of the concept of freedom of expression and non-punitive response in order to identify and correct errors in our health system. This concept is a cornerstone of the patient safety culture among healthcare professionals and plays a central role in the quality improvement strategy.</ce:para>.
November 25, 2016: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
https://www.readbyqxmd.com/read/28152762/ro-ils-radiation-oncology-incident-learning-system-data-trends-2014-2015
#13
Eric C Ford, Nadine L Eads, Ksenija Kapetanovic, Cindy Tomlinson
: 59 Background: Incident learning is one of the most effective ways to improve quality care. To facilitate patient safety improvement at a national level, American Society for Radiation Oncology (ASTRO) and American Association of Physicists in Medicine (AAPM) launched RO-ILS: Radiation Oncology Incident Learning System in June 2014. RO-ILS mission is to facilitate safer and higher quality care through a shared learning environment that is secure and non-punitive. METHODS: To ensure the security and protection of data, ASTRO contracted with Clarity PSO, a federally-certified patient safety organization that operates under the auspices of the Patient Safety and Quality Improvement Act of 2005...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28150974/why-are-conservatives-more-punitive-than-liberals-a-moral-foundations-approach
#14
Jasmine R Silver, Eric Silver
Morality is thought to underlie both ideological and punitive attitudes. In particular, moral foundations research suggests that group-oriented moral concerns promote a conservative orientation, while individual-oriented moral concerns promote a liberal orientation (Graham, Haidt, & Nosek, 2009). Drawing on classical sociological theory, we argue that endorsement of group-oriented moral concerns also elicits higher levels of punitiveness by promoting a view of crime as being perpetrated against society, while endorsement of individual-oriented moral concerns reduces punitiveness by directing attention toward the welfare of offenders as well as victims...
February 2, 2017: Law and Human Behavior
https://www.readbyqxmd.com/read/28147493/effect-of-parameter-mismatch-on-the-dynamics-of-strongly-coupled-self-sustained-oscillators
#15
Nilaj Chakrabarty, Aditya Jain, Nijil Lal, Kantimay Das Gupta, Punit Parmananda
In this paper, we present an experimental setup and an associated mathematical model to study the synchronization of two self-sustained, strongly coupled, mechanical oscillators (metronomes). The effects of a small detuning in the internal parameters, namely, damping and frequency, have been studied. Our experimental system is a pair of spring wound mechanical metronomes; coupled by placing them on a common base, free to move along a horizontal direction. We designed a photodiode array based non-contact, non-magnetic position detection system driven by a microcontroller to record the instantaneous angular displacement of each oscillator and the small linear displacement of the base, coupling the two...
January 2017: Chaos
https://www.readbyqxmd.com/read/28130916/the-human-subthalamic-nucleus-and-globus-pallidus-internus-differentially-encode-reward-during-action-control
#16
Peter Justin Rossi, Corinna Peden, Oscar Castellanos, Kelly D Foote, Aysegul Gunduz, Michael S Okun
The subthalamic nucleus (STN) and globus pallidus internus (GPi) have recently been shown to encode reward, but few studies have been performed in humans. We investigated STN and GPi encoding of reward and loss (i.e., valence) in humans with Parkinson's disease. To test the hypothesis that STN and GPi neurons would change their firing rate in response to reward- and loss-related stimuli, we recorded the activity of individual neurons while participants performed a behavioral task. In the task, action choices were associated with potential rewarding, punitive, or neutral outcomes...
January 28, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28116790/proteomics-analyses-of-prostate-cancer-cells-reveals-cellular-pathways-associated-with-androgen-resistance
#17
Naseruddin Höti, Punit Shah, Yingwei Hu, Shuang Yang, Hui Zhang
While significant advances have been made in the diagnosis and treatment of prostate cancer, each year tens of thousands of men still die from prostate cancer in the United States. Thus greater understanding of cellular pathways and molecular basis of prostate cancer progression in the development of androgen resistance is needed to treat these lethal phenotypes. To dissect the mechanism of androgen resistance, we utilize a proteomics approach to study the development of androgen resistance in LNCaP prostate cancer cells...
January 23, 2017: Proteomics
https://www.readbyqxmd.com/read/28107164/decreasing-human-trafficking-through-sex-work-decriminalization
#18
Erin Albright, Kate D'Adamo
In order to decrease human trafficking, health care workers should support the full decriminalization of prostitution. Similar to trafficking in other forms of labor, preventing trafficking in the sex trade requires addressing the different forms of marginalization that create vulnerable communities. By removing punitive laws that prevent reporting of exploitation and abuse, decriminalization allows sex workers to work more safely, thereby reducing marginalization and vulnerability. Decriminalization can also help destigmatize sex work and help resist political, social, and cultural marginalization of sex workers...
January 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/28104789/a-novel-humanized-mouse-model-of-huntington-disease-for-preclinical-development-of-therapeutics-targeting-mutant-huntingtin-alleles
#19
Amber L Southwell, Niels H Skotte, Erika B Villanueva, Michael E Østergaard, Xiaofeng Gu, Holly B Kordasiewicz, Chris Kay, Daphne Cheung, Yuanyun Xie, Sabine Waltl, Louisa Dal Cengio, Hailey Findlay-Black, Crystal N Doty, Eugenia Petoukhov, Diepiriye Iworima, Ramy Slama, Jolene Ooi, Mahmoud A Pouladi, William X Yang, Eric E Swayze, Punit P Seth, Michael R Hayden
Huntington disease (HD) is a neurodegenerative disease caused by a mutation in the huntingtin (HTT) gene. HTT is a large protein, interacts with many partners and is involved in many cellular pathways, which are perturbed in HD. Therapies targeting HTT directly are likely to provide the most global benefit. Thus there is a need for preclinical models of HD recapitulating human HTT genetics. We previously generated a humanized mouse model of HD, Hu97/18, by intercrossing BACHD and YAC18 mice with knockout of the endogenous mouse HD homolog (Hdh)...
January 18, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28102544/nursing-perceptions-of-patient-safety-climate-in-the-gaza-strip-palestine
#20
A Elsous, A Akbari Sari, Y AlJeesh, M Radwan
AIMS: This study was undertaken to assess the perception of nurses about patient safety culture and to test whether it is significantly affected by the nurses' position, age, experience and working hours. BACKGROUND: Patient safety has sparked the interest of healthcare mangers, yet there is limited knowledge about the current patient safety culture among nurses in the Gaza Strip. METHODS: This was a descriptive cross-sectional study, administering the Arabic Safety Attitude Questionnaire (Short Form 2006) to 210 nurses in four public general hospitals...
January 19, 2017: International Nursing Review
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