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Pharmaceutical care

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https://www.readbyqxmd.com/read/28928111/personalized-hypertension-management-using-patient-generated-health-data-integrated-with-electronic-health-records-empower-h-six-month-pre-post-study
#1
Nan Lv, Lan Xiao, Martha L Simmons, Lisa G Rosas, Albert Chan, Martin Entwistle
BACKGROUND: EMPOWER-H (Engaging and Motivating Patients Online With Enhanced Resources-Hypertension) is a personalized-care model facilitating engagement in hypertension self-management utilizing an interactive Web-based disease management system integrated with the electronic health record. The model is designed to support timely patient-provider interaction by incorporating decision support technology to individualize care and provide personalized feedback for patients with chronic disease...
September 19, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28925569/prescribing-errors-intercepted-by-pharmacist-intervention-in-care-of-patients-hospitalised-with-breast-and-gynaecological-cancer-at-a-brazilian-teaching-hospital
#2
A C Ferracini, A T Rodrigues, A A de Barros, S F Derchain, P G Mazzola
Oncologic inpatients often require multiple drug therapy. They may be at higher risk of experiencing prescribing errors, which pharmacist interventions may help to avoid. This study aimed to evaluate the types of prescribing errors, pharmaceutical interventions and differences in clinical significance, in prescriptions for hospitalised patients with breast and gynaecological cancer. A cross-sectional, prospective study was conducted at the oncology ward of a clinic specialised in breast and gynaecology cancer...
September 19, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28921431/cell-free-production-of-protein-biologics-within-24-h
#3
Challise J Sullivan, Erik D Pendleton, John Dresios
Protein biologics have emerged as a safe and effective group of drug products that can be used in a variety of medical disorders and clinical settings, including treatment of orphan diseases, personalized medicine, and point-of-care applications. However, the full potential of protein biologics for such applications will not be realized until there are methods available for rapid and cost-effective production of small scale products for individual needs. Here, we describe a modular and scalable method for rapid and adaptable production of protein-based medical products at small doses...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28919911/comprehensibility-of-selected-usp-pictograms-by-illiterate-and-literate-farsi-speakers-the-first-experience-in-iran-part-i
#4
Amir H Zargarzadeh, Sahar Ahamdi
BACKGROUND: Good understanding of medication instructions is paramount to a good pharmaceutical care. The aim of our study was to examine the understandability of the selected three most applicable pictograms by participants and their recall after educational mini sessions. MATERIALS AND METHODS: First, nine experienced pharmacists selected the three most potentially applicable pictograms. Pictograms A to C were determined, respectively, "A-take medication with food," "B-medication may cause drowsiness," and "C-take medication before sleep...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28919795/type-2-diabetes-in-vietnam-a-cross-sectional-prevalence-based-cost-of-illness-study
#5
Nguyen Tu Dang Le, Luyen Dinh Pham, Trung Quang Vo
BACKGROUND: According to the International Diabetes Federation, total global health care expenditures for diabetes tripled between 2003 and 2013 because of increases in the number of people with diabetes as well as in the average expenditures per patient. This study aims to provide accurate and timely information about the economic impacts of type 2 diabetes mellitus (T2DM) in Vietnam. METHOD: The cost-of-illness estimates followed a prospective, prevalence-based approach from the societal perspective of T2DM with 392 selected diabetic patients who received treatment from a public hospital in Ho Chi Minh City, Vietnam, during the 2016 fiscal year...
2017: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/28918339/interference-of-dibutylphthalate-on-human-prostate-cell-viability
#6
Mariana Di Lorenzo, Maurizio Forte, Salvatore Valiante, Vincenza Laforgia, Maria De Falco
Dibutylphthalate (DBP) is an environmental pollutant widely used as plasticizer in a variety of industrial applications worldwide. This agent can be found in personal-care products, children's toy, pharmaceuticals, food products. Exposure to DBP can occur via ingestion and inhalation as well as intravenous or skin contact. DBP belongs to the family of endocrine disrupting chemicals (EDCs) and its effects on reproductive system were demonstrated both in vivo and in vitro. In the present study we evaluated the effects of DBP on human prostate adenocarcinoma epithelial cells (LNCaP) in order to highlight xenoestrogens influence on human prostate...
September 14, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28916304/rationale-and-design-of-the-arrest-trial-investigating-mesenchymal-stem-cells-in-the-treatment-of-small-aaa
#7
S Keisin Wang, Linden A Green, Ashley R Gutwein, Natalie A Drucker, Raghu L Motaganahalli, Andres Fajardo, Clifford C Babbey, Michael P Murphy
BACKGROUND: Abdominal aortic aneurysms (AAA) are a major source of morbidity and mortality despite continuing advances in surgical technique and care. Although the inciting factors for AAA development continue to be elusive, accumulating evidence suggests a significant peri-aortic inflammatory response leading to degradation and dilation of the aortic wall. Previous human trials have demonstrated safety and efficacy of mesenchymal stem cells (MSCs) in the treatment of inflammation-related pathologies such as rheumatoid arthritis, graft vs host disease, and transplant rejection...
September 12, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28915212/22-cases-of-bia-alcl-awareness-and-outcome-tracking-from-the-italian-ministry-of-health
#8
Campanale Antonella, Boldrini Rosaria, Marletta Marcella
BACKGROUND: To date, 359 cases of anaplastic large cell lymphoma in women with breast implants (BIA-ALCL) worldwide have been reported out of more than 10 million implanted patients but Health Care Authorities suspect this is a possible underestimation and the limited number of cases makes it difficult to clarify its etiology. The General Directorate of Medical Devices and Pharmaceutical Services of the Italian Ministry of Health (IMoH) has examined and studied the Italian BIA-ALCL cases, and the aim of this study is to report on the knowledge and experience gained on this new emerging disease...
September 13, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28914069/the-role-of-a%C3%A2-hospital-pharmacist-in-the-management-of-asthma-in-great-britain
#9
Inka Sembol, Božena Macešková
The role of the pharmacist in the asthma management is well established. However, there is still a considerable number of patients with suboptimal asthma control affecting patients quality of life and resulting in poor outcomes, morbidity and mortality. The aim was to identify patients factors, explore the hospital pharmacists role in the asthma management and identify any areas for improvement in Great Britain. Qualitative data collection was selected. Patients case studies and semi-structured open interviews with the hospital multi-disciplinary team (MDT) were applied...
2017: Ceská a Slovenská Farmacie
https://www.readbyqxmd.com/read/28913485/an-in-vitro-study-of-the-release-capacity-of-the-local-anaesthetics-from-siloxane-matrices
#10
Gabriela Preda, Alexandru Florin Rogobete, Dorel Săndesc, Ovidiu Horea Bedreag, Carmen Alina Cradigati, Mirela Sarandan, Marius Papurica, Sonia Elena Popovici, Monica Dragomirescu
AIMS: In the field of anaesthesia and intensive care, the controlled release systems capable of delivering constantly local anaesthetics are of interest because of the advantages brought to pain management. In this paper we presented the release profiles by usage of siloxane matrices of two common local anaesthetics, lidocaine and bupivacaine, analysed in vitro. METHODS: The siloxane matrices were obtained in accordance with the methods described in the specialized literature, tetraethoxysilane (TEOS) and tetramethoxysilane (TMOS) were used as precursors...
October 2016: Rom J Anaesth Intensive Care
https://www.readbyqxmd.com/read/28912290/achieving-high-quality-care-a-view-from-nice
#11
REVIEW
Gillian Leng, Gemma Partridge
The National Institute for Health and Care Excellence (NICE) was established in 1999 to provide evidence-based guidance. The task of producing guidance by reviewing primary research data and using an advisory committee to develop evidence-based recommendations, is not straightforward. Guidance production is, however, less challenging than the task of putting evidence-based recommendations into practice.NICE is very sensitive to this challenge as, since 1999, over 1500 pieces of NICE guidance have been published...
September 14, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28910962/pharmaceuticals-and-other-anthropogenic-chemicals-in-atmospheric-particulates-and-precipitation
#12
Mark L Ferrey, M Coreen Hamilton, Will J Backe, Kurt E Anderson
Air and precipitation samples were analyzed by liquid chromatography tandem mass spectrometry (LC-MS/MS) and gas chromatography mass spectrometry (GC-MS) for pharmaceuticals, personal care products, and other commercial chemicals within the St. Paul/Minneapolis metropolitan area of Minnesota, U.S. Of the 126 chemicals analyzed, 17 were detected at least once. Bisphenol A, N,N-diethyl-meta-toluamide (DEET), and cocaine were the most frequently detected; their maximum concentrations in snow were 3.80, 9.49, and 0...
September 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28910237/effects-of-once-weekly-exenatide-on-cardiovascular-outcomes-in-type-2-diabetes
#13
Rury R Holman, M Angelyn Bethel, Robert J Mentz, Vivian P Thompson, Yuliya Lokhnygina, John B Buse, Juliana C Chan, Jasmine Choi, Stephanie M Gustavson, Nayyar Iqbal, Aldo P Maggioni, Steven P Marso, Peter Öhman, Neha J Pagidipati, Neil Poulter, Ambady Ramachandran, Bernard Zinman, Adrian F Hernandez
Background The cardiovascular effects of adding once-weekly treatment with exenatide to usual care in patients with type 2 diabetes are unknown. Methods We randomly assigned patients with type 2 diabetes, with or without previous cardiovascular disease, to receive subcutaneous injections of extended-release exenatide at a dose of 2 mg or matching placebo once weekly. The primary composite outcome was the first occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke...
September 14, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28910222/restricted-access-state-medicaid-coverage-of-sofosbuvir-hepatitis-c-treatment
#14
Marea B Tumber
Chronic hepatitis C (HCV) infection can persist for decades without symptoms. Many Americans are unaware of their infection status and are not receiving necessary care and treatment. This places them at greater risk for severe, even fatal, complications from the disease and increases the likelihood that they will transmit the virus to others. In late 2013, the Food and Drug Administration approved a direct acting antiviral drug called sofosbuvir to treat chronic HCV infection. Sofosbuvir is a highly effective, but very expensive, curative treatment for HCV...
January 2017: Journal of Legal Medicine
https://www.readbyqxmd.com/read/28905437/the-use-of-traditional-herbal-medicines-amongst-south-asian-diasporic-communities-in-the-uk
#15
Sukvinder K Bhamra, Adrian Slater, Caroline Howard, Mark Johnson, Michael Heinrich
Migrant South Asian communities in the UK have brought with them their own traditional forms of medicine, yet little is known about their current use of herbal medicines (HMs) in the UK. The aim of the study was to explore the origins, use and transmission of knowledge of traditional HMs used by diasporic South Asian communities in the UK. A researcher-administered questionnaire was used for data collection (n = 192). An opportunity sampling technique was used to recruit participants across several locations in Birmingham and Leicester...
September 14, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28903769/specific-barriers-to-the-conduct-of-randomised-clinical-trials-on-medical-devices
#16
REVIEW
Edmund A M Neugebauer, Ana Rath, Sunya-Lee Antoine, Michaela Eikermann, Doerthe Seidel, Carsten Koenen, Esther Jacobs, Dawid Pieper, Martine Laville, Séverine Pitel, Cecilia Martinho, Snezana Djurisic, Jacques Demotes-Mainard, Christine Kubiak, Vittorio Bertele, Janus C Jakobsen, Silvio Garattini, Christian Gluud
BACKGROUND: Medical devices play an important role in the diagnosis, prevention, treatment and care of diseases. However, compared to pharmaceuticals, there is no rigorous formal regulation for demonstration of benefits and exclusion of harms to patients. The medical device industry argues that the classical evidence hierarchy cannot be applied for medical devices, as randomised clinical trials are impossible to perform. This article aims to identify the barriers for randomised clinical trials on medical devices...
September 13, 2017: Trials
https://www.readbyqxmd.com/read/28900457/comprehensibility-of-selected-united-states-pharmacopeia-pictograms-by-illiterate-and-literate-farsi-speakers-the-first-experience-in-iran-part-ii
#17
Amir H Zargarzadeh, Sahar Ahmadi
BACKGROUND: Conveying information to patients on how to use medications at the dispensing sessions and retention of this information by the patients is essential to the good pharmaceutical care. The aim of our study was to examine the comprehensibility of the selected three potentially usable pictograms by five groups of subjects who had different levels of literacy in both before and after mini educational sessions. MATERIALS AND METHODS: Nine experienced pharmacists selected three potentially usable pictograms in Isfahan pharmacies: Pictograms D through F representing respectively: "do not take medication during pregnancy," "keep medication in the refrigerator," and "take medication with plenty of water...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28898876/filing-sources-after-oral-p2y12-platelet-inhibitors-to-the-food-and-drug-administration-adverse-event-reporting-system-faers
#18
Victor L Serebruany, Vasily Cherepanov, Moo Hyun Kim, Oleg Litvinov, Hector A Cabrera-Fuentes, Thomas A Marciniak
BACKGROUND: The US Food and Drug Administration Adverse Event Reporting System (FAERS) is a global passive surveillance database that relies on voluntary reporting by health care professionals and consumers as well as required mandatory reporting by pharmaceutical manufacturers. However, the initial filers and comparative patterns for oral P2Y12 platelet inhibitor reporting are unknown. We assessed who generated original FAERS reports for clopidogrel, prasugrel, and ticagrelor in 2015...
September 13, 2017: Cardiology
https://www.readbyqxmd.com/read/28895104/concordance-of-adherence-measurement-using-self-reported-adherence-questionnaires-and-medication-monitoring-devices-an-updated-review
#19
REVIEW
Alisha Monnette, Yichen Zhang, Hui Shao, Lizheng Shi
INTRODUCTION: As medication adherence continues to be a prevalent issue in today's society, the methods used to monitor medication-taking behaviors are constantly being re-evaluated and compared in search of the 'gold standard' measure. Our review aimed to assess the current literature surrounding the correlation between self-reported questionnaires (SRQs) and electronic monitoring devices to determine if these measures produce similar results. METHODS: We performed a literature search from 2009 to 2017 using PubMed, PubMed In-Process and Non-Indexed, EMBASE, Ovid MEDLINE, and Ovid MEDLINE In-Process...
September 11, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28894532/an-ethno-pharmacological-study-of-plants-used-for-traditional-medication-in-tangail-district-bangladesh
#20
A H M Mahmudur Rahman, Mahmoud Rafieian-Kopaei
BACKGROUND: In Bangladesh, folk medicinal practitioners are called "Kaviraj" and are consulted for treatment of various ailments by a large part of the rural and urban population. There are some previous studies conducted in the Tangail district of Bangladesh about medicinal plants, but there is no relevant information about this aspect in some parts of this district. AIM: To conduct an ethno-pharmacological survey among the "Kaviraj" of two upazilas (regions) in Tangail district, namely Tangail Sadar Upazila and Nagarpur Upazila, to identify the trouble-free formulations of medicinal plants for various diseases used by the folk medicine practitioners on or after other forms of medical practices...
July 2017: Electronic Physician
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