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Pharmaceutical care

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https://www.readbyqxmd.com/read/29146489/exploring-the-barriers-to-and-facilitators-of-using-evidence-based-drugs-in-the-secondary-prevention-of-cardiovascular-diseases-findings-from-a-multistakeholder-qualitative-analysis
#1
Victoria Miller, Lavanya Nambiar, Malvika Saxena, Darryl Leong, Amitava Banerjee, José Pablo Werba, Jose Rocha Faria Neto, Katherine Curi Quinto, Mohammed Moniruzzaman, Shweta Khandelwal
BACKGROUND: Health-system barriers and facilitators associated with cardiovascular medication adherence have seldom been studied, particularly in low- and middle-income countries where uptake rates are poorest. OBJECTIVES: This study sought to explore the major obstacles and facilitators to the use of evidence-supported medications for secondary prevention of cardiovascular disease using qualitative analysis in 2 diverse countries across multiple levels of their health care systems...
November 13, 2017: Global Heart
https://www.readbyqxmd.com/read/29139019/pharmacists-confidence-when-providing-pharmaceutical-care-on-anticoagulants-a-multinational-survey
#2
John Papastergiou, Nadir Kheir, Katerina Ladova, Silas Rydant, Fabio De Rango, Sotiris Antoniou, Reka Viola, Maria Dolores Murillo, Stephane Steurbaut, Filipa Alves da Costa
Background Guidelines on the management of orally anticoagulated patients are continuously evolving, leading to an increased need for pharmacists to be fully integrated in care provision. Objective To identify self-reported gaps in confidence among practicing pharmacists in the area of anticoagulation. Setting Pharmacists in different work settings in different countries. Method Cross-sectional international survey from October 2015 till November 2016 among pharmacists working in different settings to assess their level of confidence when delivering anticoagulants as well as to identify possible educational needs regarding this medication class...
November 14, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29138584/repeated-intermittent-ulipristal-acetate-in-the-treatment-of-uterine-fibroids-a-cost-effectiveness-analysis
#3
Kirk Geale, Ertan Saridogan, Matthieu Lehmann, Pablo Arriagada, Marcus Hultberg, Martin Henriksson
There are limited treatment options available for women with moderate to severe symptoms of uterine fibroids (UFs) who wish to avoid surgery. For these women, treatment with standard pharmaceuticals such as contraceptives is often insufficient to relieve symptoms, and patients may require surgery despite their wish to avoid it. Clinical trials demonstrate that ulipristal acetate 5 mg (UPA) is an effective treatment for this patient group, but its cost-effectiveness has not been assessed in this population. A decision-analytic model was developed to simulate a cohort of patients in this population under treatment with UPA followed by surgery as needed compared to treatment with iron and non-steroidal anti-inflammatory drug (NSAID) followed by surgery as needed (best supportive care, BSC)...
2017: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29137502/innovative-product-development-partnership-reduced-neonatal-mortality-in-nepal-through-improved-umbilical-cord-care
#4
Peter Oyloe, Leela Khanal, Stephen Hodgins, Sabita T Pradhan, Penny Dawson
Approximately 40 percent of all newborn deaths in Nepal are attributable to neonatal infections. A randomized controlled trial conducted in Nepal in the period 2002-05 on the application of a solution of the disinfectant chlorhexidine to umbilical cord stumps of newborns showed a reduced risk of infections and death. In response to these results, the Government of Nepal and various partners mobilized to deliver this simple, low-cost intervention on a national scale. We describe the design, development, and maturation of a partnership among the government, technical assistance agencies, and a local pharmaceutical company to create a suitable, commercially available gel product to reduce newborn infections...
November 2017: Health Affairs
https://www.readbyqxmd.com/read/29133323/characteristics-and-healthcare-utilisation-patterns-of-high-cost-beneficiaries-in-the-netherlands-a-cross-sectional-claims-database-study
#5
Joost Johan Godert Wammes, Marit Tanke, Wilma Jonkers, Gert P Westert, Philip Van der Wees, Patrick Pt Jeurissen
OBJECTIVE: To determine medical needs, demographic characteristics and healthcare utilisation patterns of the top 1% and top 2%-5% high-cost beneficiaries in the Netherlands. DESIGN: Cross-sectional study using 1 year claims data. We broke down high-cost beneficiaries by demographics, the most cost-incurring condition per beneficiary and expensive treatment use. SETTING: Dutch curative health system, a health system with universal coverage...
November 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29132369/impact-of-pharmacist-led-medication-management-in-care-transitions
#6
Seungwon Yang
BACKGROUND: When patients are discharged from hospital to home, it is a highlighted vulnerable period for which medication - related problems are prevalent. Researchers have proposed a telephone follow-up intervention as a means to reduce hospital readmissions. However, the outcome of the intervention with the engagement of pharmacists in managing patients' medicines after discharge has not been well explored. The objectives of this study were (1) to determine whether a pharmacist telephone follow-up intervention focusing on patients' medicines management support is associated with a reduction in 30-day readmission rates and (2) to describe the number and types of pharmacist interventions in care transitions...
November 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29132000/reconciling-monitoring-and-modeling-an-appraisal-of-river-monitoring-networks-based-on-a-spatial-autocorrelation-approach-emerging-pollutants-in-the-danube-river-as-a-case-study
#7
A Ginebreda, L Sabater-Liesa, A Rico, A Focks, D Barceló
Rivers extend in space and time under the influence of their catchment area. Our perception largely relies on discrete spatial and temporal observations carried out at certain sites located throughout the catchment (monitoring networks, MN). However, MNs are constrained by (a) the distribution of sampling sites, (b) the dynamics of the variable considered and (c) the river hydrological conditions. In this study, all three aspects were captured and quantified by applying a spatial autocorrelation modeling approach...
November 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29130513/falls-and-hip-fractures-associated-with-urinary-incontinence-among-older-men-and-women-with-complex-needs-a-national-population-study
#8
Philip J Schluter, Edwin P Arnold, Hamish A Jamieson
AIMS: To determine if urinary incontinence (UI) was an independent risk factor for falls and hip fractures in community-dwelling older men and women with complex needs, after controlling for confounders. METHODS: Since 2012, all community care recipients in New Zealand have undergone standardized needs assessments using the Home Care International Residential Assessment Instrument (interRAI-HC). The interRAI-HC elicits information over multiple domains, including UI frequency and falls...
November 11, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29128385/the-effectiveness-of-shingles-vaccine-among-albertans-aged-50%C3%A2-years-or-older-a-retrospective-cohort-study
#9
Bruce M McDonald, Douglas C Dover, Kimberley A Simmonds, Christopher A Bell, Lawrence W Svenson, Margaret L Russell
PURPOSE: We assessed the effectiveness of shingles vaccine in preventing incident shingles among Alberta residents aged 50 years or older over the period 2009 - 2015, using administrative health data. METHODS: The cohort comprised of Albertans from the Alberta Health Care Insurance Plan Registry (AHCIP) as of June 30, 2009 and aged 50 years or older. Those who received shingles vaccine were identified from the provincial pharmaceutical information network. The occurrence of incident shingles was identified through both inpatient and outpatients/community care data...
November 8, 2017: Vaccine
https://www.readbyqxmd.com/read/29127827/spectrophotometric-and-spectrofluorimetric-methods-for-determination-of-certain-biologically-active-phenolic-drugs-in-their-bulk-powders-and-different-pharmaceutical-formulations
#10
Mahmoud A Omar, Kalid M Badr El-Din, Hesham Salem, Osama H Abdelmageed
Two simple and sensitive spectrophotometric and spectrofluorimetric methods for the determination of terbutaline sulfate, fenoterol hydrobromide, etilefrine hydrochloride, isoxsuprine hydrochloride, ethamsylate, doxycycline hyclate have been developed. Both methods were based on the oxidation of the cited drugs with cerium (IV) in acid medium. The spectrophotometric method was based on measurement of the absorbance difference (ΔA), which represents the excess cerium (IV), at 317nm for each drug. On the other hand, the spectrofluorimetric method was based on measurement of the fluorescent of the produced cerium (III) at emission wavelength 354nm (λexcitation=255nm) for the concentrations studied for each drug...
November 8, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29126634/-antiepileptic-drugs-administration-by-nasogastric-tube-in-comatose-patients
#11
Rim Charfi, Ramla Mizouri, Mouna Ben Sassi, Emna Gaies, Hanene Eljebari, Nadia Jebabli, Sarrah Zereï, Fatma Ben Salem, Dorra Ben Said, Anis Klouz, Riadh Daghfous, Issam Salouage, Sameh Trabelsi
AIM: To evaluate the modalities of administration of antiepileptic drugs (AED) with nasogastric tube (NGT) by nurses and to draw up recommendations. METHODS: Our study consisted on investigating the modalities of administration of AED's with NGT by nurses during four months. We prepared 10 questions including demographic information. Participation was voluntary and anonymous. The questionnaire was distributed in seven intensive care departments after authorization of each head of the department...
October 12, 2017: Thérapie
https://www.readbyqxmd.com/read/29124632/revealed-and-stated-preferences-of-decision-makers-for-priority-setting-in-health-technology-assessment-a-systematic-review
#12
REVIEW
Peter Ghijben, Yuanyuan Gu, Emily Lancsar, Silva Zavarsek
BACKGROUND: There is much interest from stakeholders in understanding how health technology assessment (HTA) committees make national funding decisions for health technologies. A growing literature has analysed past decisions by committees (revealed preference, RP studies) and hypothetical decisions by committee members (stated preference, SP studies) to identify factors influencing decisions and assess their importance. OBJECTIVES: A systematic review of the literature was undertaken to provide insight into committee preferences for these factors (after controlling for other factors) and the methods used to elicit them...
November 9, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/29118291/-outcomes-of-pharmaceutical-faculty-focused-introduction-to-nursing-education-for-pharmacy-students-a-questionnaire-survey
#13
Takashi Majima, Hiroshi Ohara
  The scope of pharmaceutical education in Japan has been expanding, and with it an awareness of the importance of team medical care. However, pharmaceutical education still gives little attention to the psychosocial aspects of care, instead focusing on the structures and functions of drugs. In contrast, nursing education emphasizes the fact that medical care involves patients' family and significant others as much as the patients themselves, and thus nursing students are taught the basic needs and developmental stages of those people requiring care alongside their practical nursing skills...
November 9, 2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/29115368/-evolution-of-the-complexity-index-of-the-antiretroviral-therapy-in-hiv-patients-in-a-real-life-clinical-practice
#14
M Manzano-García, A Robustillo-Cortés, C V Almeida-González, R Morillo-Verdugo
OBJECTIVE: HIV infection has been one of the biggest successes in the healthcare world, mainly due to the appearance of antiretroviral treatment (ART). The complexity of this type of treatment has been one of the decisive factors in the follow-up of these patients. METHODS: An analytical, unicentric, retrospective observational study. We included all patients older than 18 years of age who were diagnosed with HIV who received ART in follow-up for the consultation of pharmaceutical pathology care during the year 2015...
November 7, 2017: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/29114831/factors-associated-with-increases-in-us-health-care-spending-1996-2013
#15
Joseph L Dieleman, Ellen Squires, Anthony L Bui, Madeline Campbell, Abigail Chapin, Hannah Hamavid, Cody Horst, Zhiyin Li, Taylor Matyasz, Alex Reynolds, Nafis Sadat, Matthew T Schneider, Christopher J L Murray
Importance: Health care spending in the United States increased substantially from 1995 to 2015 and comprised 17.8% of the economy in 2015. Understanding the relationship between known factors and spending increases over time could inform policy efforts to contain future spending growth. Objective: To quantify changes in spending associated with 5 fundamental factors related to health care spending in the United States: population size, population age structure, disease prevalence or incidence, service utilization, and service price and intensity...
November 7, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29112490/implementation-of-specialized-pharmaceutical-care-hospital-outpatient-clinics-in-a-hospital-pharmacy-department
#16
Luis Margusino-Framiñán, Purificación Cid-Silva, Cristina Martínez-Roca, Marta García-Queiruga, Elena Fernández-Gabriel, María Mateos-Salvador, María Teresa Rabuñal-Álvarez, María Isaura Pedreira-Vázquez, Isabel Martín-Herranz
OBJECTIVE: To describe the organization of patient care into Specialized Pharmaceutical Care Hospital Outpatient Clinics in a Hospital Pharmacy Department, to evaluate their healthcare quality, and the quality  perceived by outpatients. METHOD: A retrospective observational study in a High-Level Hospital Pharmacy Department during three periods (years 2010, 2013 and 2016); description of  the organization at the levels of structure, human resources, material resources  and working procedures; evaluation of healthcare quality through the analysis of  three variables in terms of procedure: prior appointment compliance, waiting  time and documentation of pharmaceutical care; evaluation of quality perceived  by outpatients through a satisfaction survey; comparative statistical analysis of  means (Student's t) and proportions (Pearson's chi square)...
November 1, 2017: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/29105237/scientism-conflicts-of-interest-and-the-marginalization-of-ethics-in-medical-education
#17
Christopher Mayes, Jane Williams, Ian Kerridge, Wendy Lipworth
AIM: This paper reports on the findings from 6 focus groups conducted with Australian medical students. The focus groups sought students' perspectives on how the influence of commercial interests on medical practice and education could be managed. METHOD: We conducted 6 focus groups with medical students in New South Wales, Australia. Participants were recruited via student-run medical society and faculty e-mail lists. Forty-nine students from 6 medical schools in New South Wales participated...
November 3, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29102480/what-are-the-key-elements-for-implementing-intensive-primary-care-a-multisite-veterans-health-administration-case-study
#18
Evelyn T Chang, Pushpa V Raja, Susan E Stockdale, Marian L Katz, Donna M Zulman, Jessica A Eng, Kathy H Hedrick, Jeffrey L Jackson, Neha Pathak, Brook Watts, Carrie Patton, Gordon Schectman, Steven M Asch
Many integrated health systems and accountable care organizations have turned to intensive primary care programs to improve quality of care and reduce costs for high-need high-cost patients. How best to implement such programs remains an active area of discussion. In 2014, the Veterans Health Administration (VHA) implemented five distinct intensive primary care programs as part of a demonstration project that targeted Veterans at the highest risk for hospitalization. We found that programs evolved over time, eventually converging on the implementation of the following elements: 1) an interdisciplinary care team, 2) chronic disease management, 3) comprehensive patient assessment and evaluation, 4) care and case management, 5) transitional care support, 6) preventive home visits, 7) pharmaceutical services, 8) chronic disease self-management, 9) caregiver support services, 10) health coaching, and 11) advanced care planning...
October 25, 2017: Healthcare
https://www.readbyqxmd.com/read/29100727/operative-and-therapeutic-advancements-in-breast-cancer-metastases-to-the-brain
#19
REVIEW
Rahul Jandial, Reid Hoshide, J Dawn Waters, George Somlo
Patients with breast cancer are surviving longer as the state of the art for care advances. Because patients are surviving longer with primary breast cancer, the incidence of secondary metastatic disease has risen. Metastatic breast cancer to the brain was once thought to be universally fatal. While it is still quite lethal, its treatment after diagnosis is increasingly safe and effective. Critical progress has been made in understanding the interaction between breast metastases and the neural niche, neuroimaging of functional anatomy, minimally invasive image-guided brain surgery, characterizing subtypes of breast cancer based on molecular and genetic profiles, and individualized pharmaceuticals and immunotherapies...
October 7, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29094614/role-of-topical-oxymetazoline-for-management-of-erythematotelangiectatic-rosacea
#20
Rebecca M Hoover, John Erramouspe
OBJECTIVE: To review and summarize topical oxymetazoline's pharmacology, pharmacokinetics, efficacy, safety, cost, and place in therapy for persistent redness associated with erythematotelangiectatic rosacea. DATA SOURCES: Literature searches of MEDLINE (1975 to September 2017), International Pharmaceutical Abstracts (1975 to September 2017), and Cochrane Database (publications through September 2017) using the terms rosacea, persistent redness, α -agonist, and oxymetazoline...
November 1, 2017: Annals of Pharmacotherapy
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