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Elephant man

Kishore L Jayakumar, Jules B Lipoff
No abstract text is available yet for this article.
July 1, 2017: JAMA Dermatology
Rikako Takamaru, Koji Kawahito, Kei Aizawa, Yoshio Misawa
Symptomatic intravascular hemolysis after prosthetic aortic graft replacement is rare. It is primarily attributed to mechanical injury of red blood cells caused by stenosis of the vascular graft. A 50-year-old man presented with hemolytic anemia, 5 years after total arch replacement with an elephant trunk for type A aortic dissection. The hemolysis was caused by graft stenosis of the elephant trunk. Endovascular treatment for the stenotic elephant trunk was successfully performed. The postoperative course was uneventful, and the hemolysis was resolved immediately after operation...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
Hiroto Kitahara, Tomohiro Takeda, Kazumi Akasaka, Hiroyuki Kamiya
An 83-year-old man with arch aneurysm underwent total arch replacement with frozen elephant trunk and extra-anatomical left subclavian artery bypass. One year later, he felt dizziness associated with head rotation. The hypoplastic left vertebral artery was occluded by a thrombus extending from the left subclavian artery ligation site, and the dynamic stenosis of right vertebral artery by head rotation induced dizziness. He was diagnosed with Bow Hunter syndrome. Vertebral artery hypoplasia represents a possible cause of this rare complication...
May 1, 2017: Interactive Cardiovascular and Thoracic Surgery
Maryam Ganjali, Mojtaba Keighobadi
Myiasis is the infection caused by a variety of dipterous (fly) larvae in vertebrate's tissue (man and domestic or wild animals). Species of Gasterophilus are obligate parasite of horses, donkeys, zebras, elephants and rhinoceroses. There are records worldwide, but mostly, in tropical and subtropical regions. This case report describes a type of gastric myiasis caused by G. intestinalis in an old lion in a zoo in Sistan, southeast Iran. Myiasis in lions is rarely reported and this is the first report of gastric myiasis in lion...
September 2016: Journal of Arthropod-borne Diseases
John Kokotsakis, Omar A Jarral, Leanne Harling, Panteleimon Tsipas, Thanos Athanasiou
BACKGROUND: A 59-year old man being investigated for back pain was found to have aneurysmal dilatation of a right-sided aortic arch and descending thoracic aorta together with an aberrant left subclavian artery. CASE PRESENTATION: He underwent repair of this utilising the frozen elephant trunk technique, which dealt with all three pathologies in one-stage. He made an unremarkable recovery and was discharged home on the 8th post-operative day. CONCLUSIONS: This case report further demonstrates the flexibility and safety of the frozen elephant trunk in dealing with complex aortic pathology as a single-stage procedure...
May 5, 2016: Journal of Cardiothoracic Surgery
Licht Miyamoto
The number of patients with metabolic disorders is dramatically increasing all over the world. The diseases often exhibit multiple metabolic disturbances including diabetes, hyperlipidemia, and obesity, and so on, recognized as a concept of metabolic syndrome. It is important to consider the common underlying pathophysiological bases of such metabolic diseases at the suggestion of the teachings of a parable, "The blind men and an elephant," whereby each blind man investigates a different part of the elephant...
2016: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
Peter Leusink, Thea H A M van der Waart, Christine M Segeren, Tiny Jaarsma
Recently, the Dutch College of General Practitioners released a Practice Guideline on Sexual Problems which provides clear directives for the diagnosis and management of various sexual disorders in men and women. Patients who are managed in general practice and in outpatient clinics might experience distress related to sexual problems due to their age, medical condition or treatment, or distress related to problems in establishing and maintaining intimate relationships. We present two clinical cases. The first case is a woman aged 44 years with breast cancer treated by mastectomy and adjuvant tamoxifen...
2016: Nederlands Tijdschrift Voor Geneeskunde
Paolo Magagna, Giovanni Domenico Cresce, Stefano Auriemma, Loris Salvador
The management of the left subclavian artery (LSA) revascularization during aortic arch surgery is controversial and often challenging, especially during an emergency life-saving procedure. We report on a case of a 64-year old man, admitted to our institution with a Type A acute aortic dissection who underwent a frozen elephant trunk procedure with debranching of the supra-aortic vessels completed with an LSA revascularization using the in situ left internal mammary artery.
July 2016: Interactive Cardiovascular and Thoracic Surgery
S Rössner
No abstract text is available yet for this article.
April 2016: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
Laura Bennett, Stephen Dunham, Lisa Yon, Sarah Chapman, Megan Kenaghan, Laura Purdie, Rachael Tarlinton
INTRODUCTION: EEHV-1 is a viral infection of elephants that has been associated with a fatal haemorrhagic syndrome in Asian elephants. Previous studies have suggested that pregnant animals may shed more virus than non-pregnant animals. METHODS: This study examined whether pregnancy affected the frequency or magnitude of shedding of elephant endotheliotropic herpesvirus 1 (EEHV1) using Taq man real-time PCR on trunk washes from four female elephants from a UK collection over three time periods between 2011 and 2014...
2015: Veterinary Record Open
Hilary Rowe
No abstract text is available yet for this article.
July 18, 2015: Lancet
J Michael Bedford
Men are notable for low sperm production, relative to that of other large mammals, and often inferior morphology and motility of their spermatozoa. The extent to which temperature plays a role in this picture has been a moot point. However, animal experiments suggest that an increased scrotal temperature of approximately +4°C brought by inguinal clothing has a negative impact on the germinal epithelium and on the epididymis in man. In two animal species with inguinal testes, their transposition to the abdomen, raising the testis temperature by a modest approximate 1...
October 2015: Biology of Reproduction
Krister Brantberg, Babak Falahat, Daniela C Kalthoff
CONCLUSION: X-ray CT of an Asian elephant's skull suggest that elephants do not have a labyrinthine 3(rd) mobile window. This excludes the concept that elephants benefit from enhancement of bone conducted vibration by an extra opening of the labyrinth. This finding does not, however, exclude that elephants use bone conducted hearing for seismic detection, nor that other species may use an extra labyrinthine opening for improved detection of seismic signals. OBJECTIVES: In man, a pathologic extra opening of the bony labyrinth causes altered hearing with supranormal bone conduction...
2015: Acta Oto-laryngologica
Mulat Yimer, Tadesse Hailu, Wondemagegn Mulu, Bayeh Abera
Elephantiasis is a symptom of a variety of diseases that is characterized by the thickening of the skin and underlying tissues, especially in the legs, male genitals and female breasts. Some conditions having this symptom include: Elephantiasis nostras, due to longstanding chronic lymphangitis; Elephantiasis tropica or lymphatic filariasis, caused by a number of parasitic worms, particularly Wuchereria bancrofti; non-filarial elephantiasis or podoconiosis, an immune disease caused by heavy metals affecting the lymph vessels; proteus syndrome, the genetic disorder of the so-called Elephant Man, etc...
June 2015: Journal of Vector Borne Diseases
Daryl Li-Tian Yeo, Sajjad Haider, Claire Alexandra Chew Zhen
Right-sided aortic arch (RAA) is a rare congenital developmental variant present in about 0.1 percent of the population. This anatomical anomaly is commonly associated with congenital heart disease and complications from compression of mediastinal structures. However, it is unknown if patients are at a higher risk of blunt thoracic aortic injury (BTAI). We report a case of a 20-year-old man admitted to the hospital after being hit by an automobile. Computed tomographic scan revealed an RAA with an aberrant left subclavian artery originating from a Kommerell's diverticulum...
March 2015: Yale Journal of Biology and Medicine
A B Kay
In 1879 Paul Ehrlich published his technique for staining blood films and his method for differential blood cell counting using coal tar dyes and mentions the eosinophil for the first time. Eosin is a bright red synthetic dye produced by the action of bromine on fluorescein and stains basic proteins due to its acidic nature. It was discovered in 1874 by Heinrich Caro, Director of the German chemical company Badische Anilin- und Soda-Fabrik. Ehrlich introduced the term 'eosinophil' to describe cells with granules (which he called alpha-granules) having an affinity for eosin and other acid dyes...
March 2015: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
Eiji Yoshikawa, Nobuhisa Ohno, Mamoru Hamuro, Kousuke Yoshizawa, Kenta Imai, Hisao Nagato, Masanao Touma, Keiichi Fujiwara
We report a case of giant cell arteritis that was incidentally diagnosed during a hybrid( open surgical and endovascular) approach to an extensive thoracic aortic disease. A 78-year-old man was admitted for the evaluation and treatment of annuloaortic ectasia and an extensive thoracic aortic aneurysm. We performed aortic root replacement (Bentall procedure) and total aortic arch replacement using the elephant trunk technique under hypothermic circulatory arrest. Pathological examination of the aneurysmal wall revealed giant cell arteritis...
November 2014: Kyobu Geka. the Japanese Journal of Thoracic Surgery
Keizo Tanaka, Kuniyoshi Tanaka, Kayoko Natsume, Kiyohito Yamamoto, Takane Hiraiwa
A 50-year-old man presented with an acute type A aortic dissection with an aberrant right subclavian artery. Emergent total arch replacement with an elephant trunk was performed. Intraoperatively, the origin of the aberrant right subclavian artery could not be resected because it was located too far from the distal arch. After two weeks, the patient became aware of dysphagia. Postoperative computed tomography showed the esophagus was compressed anteriorly by the aneurismal origin of this aberrant vessel (Kommerell diverticulum) with a patent false lumen...
2014: Annals of Vascular Diseases
Catherine Huntley, Angus Hodder, Manoj Ramachandran
Joseph Merrick, the Elephant Man, presented to the Royal London Hospital in 1884 with an obscure condition that puzzled his contemporaries, and fascinates clinicians to this day. Throughout the 1900s, a number of theories were advanced to explain the numerous growths that covered his body: neurofibromatosis, Proteus syndrome, and a combination of childhood injury, fibrous dysplasia, and pyarthrosis. The debate continued throughout the 20th century without resolution. Today, new consensus on the genetic and clinical diagnosis of neurofibromatosis and Proteus syndrome has allowed advancements in the Elephant Man's diagnosis...
January 15, 2015: Gene
Haruna Araki, Tadashi Kitamura, Tetsuya Horai, Ko Shibata, Kagami Miyaji
OBJECTIVES: The elephant trunk technique for aortic dissection is useful for reducing false lumen pressure; however, a folded vascular prosthesis inside the aorta can cause haemolysis. The purpose of this study was to investigate whether an elephant trunk in a small-calibre lumen can cause haemolysis. METHODS: Inpatient and outpatient records were retrospectively reviewed. RESULTS: Two cases of haemolytic anaemia after aortic surgery using the elephant trunk technique were identified from 2011 to 2013...
December 2014: Interactive Cardiovascular and Thoracic Surgery
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