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https://www.readbyqxmd.com/read/28812002/image-guided-thermal-ablation-with-mr-based-thermometry
#1
REVIEW
Mingming Zhu, Ziqi Sun, Chin K Ng
Thermal ablation techniques such as radiofrequency, microwave, high intensity focused ultrasound (HIFU) and laser have been used as minimally invasive strategies for the treatment of variety of cancers. MR thermometry methods are readily available for monitoring thermal distribution and deposition in real time, leading to decrease of incidents of normal tissue damage around targeted lesion. HIFU and laser-induced thermal therapy (LITT) are the two widely accepted tumor ablation techniques because of their compatibility with MR systems...
June 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28812000/diagnostic-imaging-features-of-necrotizing-enterocolitis-a-narrative-review
#2
REVIEW
Francesco Esposito, Rosanna Mamone, Marco Di Serafino, Carmela Mercogliano, Valerio Vitale, Gianfranco Vallone, Patrizia Oresta
Necrotizing enterocolitis (NEC) is an inflammatory process, characterized by intestinal necrosis of variable extension, leading to perforation, generalized peritonitis and death. The classical pathogenetic theory focuses on mucosal damage related to a stress induced intestinal ischemia leading to mucosal injury and bacterial colonization of the wall. A more recent hypothesis emphasizes the role of immaturity of gastrointestinal and immune system, particularly of the premature, responsible of bowel wall vulnerability and suffering...
June 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28810261/comparative-evaluation-of-magnetic-resonance-guided-focused-ultrasound-surgery-for-essential-tremor
#3
Minsoo Kim, Na Young Jung, Chang Kyu Park, Won Seok Chang, Hyun Ho Jung, Jin Woo Chang
BACKGROUND: Treatment options for patients with drug-resistant essential tremor (ET) are limited. Magnetic resonance-guided focused ultrasound surgery (MRgFUS) is an emerging technique to treat refractory ET. OBJECTIVES: To present MRgFUS as an alternative to radiofrequency (RF) thalamotomy or deep brain stimulation (DBS) for ET treatment. METHODS: We retrospectively analyzed 59 patients who underwent unilateral surgery for drug-resistant ET...
August 16, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/28809681/a-prototype-therapy-system-for-transcutaneous-application-of-boiling-histotripsy
#4
Adam D Maxwell, Petr V Yuldashev, Wayne Kreider, Tatiana D Khokhlova, George R Schade, Timothy L Hall, Oleg A Sapozhnikov, Michael R Bailey, Vera A Khokhlova
Boiling histotripsy is a method of focused ultrasound surgery that noninvasively applies millisecond-length pulses with high-amplitude shock fronts to generate liquefied lesions in tissue. Such a technique requires unique outputs compared to a focused ultrasound thermal therapy apparatus, particularly to achieve high in situ pressure levels through intervening tissue. This article describes the design and characterization of a system capable of producing the necessary pressure to transcutaneously administer boiling histotripsy therapy through clinically relevant overlying tissue paths using pulses with duration up to 10 ms...
August 14, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28809083/laser-induced-focused-ultrasound-for-cavitation-treatment-toward-high-precision-invisible-sonic-scalpel
#5
Taehwa Lee, Wei Luo, Qiaochu Li, Hakan Demirci, L Jay Guo
Beyond the implementation of the photoacoustic effect to photoacoustic imaging and laser ultrasonics, this study demonstrates a novel application of the photoacoustic effect for high-precision cavitation treatment of tissue using laser-induced focused ultrasound. The focused ultrasound is generated by pulsed optical excitation of an efficient photoacoustic film coated on a concave surface, and its amplitude is high enough to produce controllable microcavitation within the focal region (lateral focus <100 µm)...
August 15, 2017: Small
https://www.readbyqxmd.com/read/28804937/breast-tumor-classification-based-on-a-computerized-breast-imaging-reporting-and-data-system-feature-system
#6
Mengyun Qiao, Yuzhou Hu, Yi Guo, Yuanyuan Wang, Jinhua Yu
OBJECTIVES: This work focused on extracting novel and validated digital high-throughput features to present a detailed and comprehensive description of the American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) with the goal of improving the accuracy of ultrasound breast cancer diagnosis. METHODS: First, the phase congruency approach was used to segment the tumors automatically. Second, high-throughput features were designed and extracted on the basis of each BI-RADS category...
August 14, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28804751/ultrasound-imaging-and-segmentation-of-bone-surfaces-a-review
#7
Ilker Hacihaliloglu
Due to its real-time, non-radiation based three-dimensional (3D) imaging capabilities, ultrasound (US) has been incorporated into various orthopedic procedures. However, imaging artifacts, low signal-to-noise ratio (SNR) and bone boundaries appearing several mm in thickness make the analysis of US data difficult. This paper provides a review about the state-of-the-art bone segmentation and enhancement methods developed for two-dimensional (2D) and 3D US data. First, an overview for the appearance of bone surface response in B-mode data is presented...
June 2017: Technology
https://www.readbyqxmd.com/read/28802056/different-nerve-ultrasound-patterns-in-charcot-marie-tooth-types-and-hnpp
#8
Luca Padua, Daniele Coraci, Marta Lucchetta, Ilaria Paolasso, Costanza Pazzaglia, Giuseppe Granata, Mario Cacciavillani, Marco Luigetti, Fiore Manganelli, Chiara Pisciotta, Giuseppe Piscosquito, Davide Pareyson, Chiara Briani
INTRODUCTION: Nerve ultrasound in Charcot-Marie-Tooth disease (CMT) has mostly focused on upper limbs. We performed an evaluation of a large cohort of CMT patients in which we sonographically characterized nerve abnormalities in different disease types, ages and nerves. METHODS: Seventy patients affected by different CMT types and hereditary neuropathy with liability to pressure palsies (HNPP) were evaluated, assessing median, ulnar, fibular, tibial and sural nerves bilaterally...
August 12, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28798066/reply-to-silburt-et-al-concerning-sterile-inflammation-following-focused-ultrasound-and-microbubbles-in-the-brain
#9
Zsofia I Kovacs, Scott R Burks, Joseph A Frank
No abstract text is available yet for this article.
August 10, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28796617/segmentation-of-3d-high-frequency-ultrasound-images-of-human-lymph-nodes-using-graph-cut-with-energy-functional-adapted-to-local-intensity-distribution
#10
Jen-Wei Kuo, Jonathan Mamou, Yao Wang, Emi Saegusa-Beecroft, Junji Machi, Ernest J Feleppa
Previous studies by our group have shown that three-dimensional high-frequency quantitative ultrasound methods have the potential to differentiate metastatic lymph nodes from cancer-free lymph nodes dissected from human cancer patients. To successfully perform these methods inside the lymph node parenchyma, an automatic segmentation method is highly desired to exclude the surrounding thin layer of fat from quantitative ultrasound processing and accurately correct for ultrasound attenuation. In high-frequency ultrasound images of lymph nodes, the intensity distribution of lymph node parenchyma and fat varies spatially because of acoustic attenuation and focusing effects...
August 9, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28796615/effects-of-signal-saturation-on-qus-parameter-estimates-based-on-high-frequency-ultrasound-signals-acquired-from-isolated-cancerous-lymph-nodes
#11
Kazuki Tamura, Jonathan Mamou, Alain Coron, Kenji Yoshida, Ernest J Feleppa, Tadashi Yamaguchi
Choosing an appropriate dynamic range for acquiring radio-frequency (RF) data from a high-frequency ultrasound (HFU) system is challenging because signals can vary greatly in amplitude as a result of focusing and attenuation effects. In addition, quantitative ultrasound (QUS) results are altered by saturated data. In this study, the effects of saturation on QUS estimates of effective scatterer diameter (ESD) and effective acoustic concentration (EAC) were quantified using simulated and experimental RF data...
August 7, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28796606/directional-transverse-oscillation-vector-flow-estimation
#12
Jorgen Arendt Jensen
A method for estimating vector velocities using transverse oscillation (TO) combined with directional beamforming is presented. In directional TO (DTO), a normal focused field is emitted and the received signals are beamformed in the lateral direction transverse to the ultrasound beam to increase the amount of data for vector velocity estimation. The approach is self-calibrating as the lateral oscillation period is estimated from the directional signal through a Fourier transform to yield quantitative velocity results over a large range of depths...
August 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28796487/endogenous-catalytic-generation-of-o2-bubbles-for-in-situ-ultrasound-guided-high-intensity-focused-ultrasound-ablation
#13
Tianzhi Liu, Nan Zhang, Zhigang Wang, Meiying Wu, Yu Chen, Ming Ma, Hangrong Chen, Jianlin Shi
High intensity focused ultrasound (HIFU) surgery generally suffers from poor precision and low efficiency in clinical application, especially for cancer therapy. Herein, a multiscale hybrid catalytic nanoreactor (catalase@MONs, abbreviated as C@M) has been developed as a tumor-sensitive contrast and synergistic agent (C&SA) for ultrasound-guided HIFU cancer surgery, by integrating dendritic-structured mesoporous organosilica nanoparticles (MONs) and catalase immobilized in the large open pore channels of MONs...
August 16, 2017: ACS Nano
https://www.readbyqxmd.com/read/28795530/construction-of-silica-based-micro-nanoplatforms-for-ultrasound-theranostic-biomedicine
#14
REVIEW
Yang Zhou, Xiaoxia Han, Xiangxiang Jing, Yu Chen
Ultrasound (US)-based biomedicine has been extensively explored for its applications in both diagnostic imaging and disease therapy. The fast development of theranostic nanomedicine significantly promotes the development of US-based biomedicine. This progress report summarizes and discusses the recent developments of rational design and fabrication of silica-based micro/nanoparticles for versatile US-based biomedical applications. The synthetic strategies and surface-engineering approaches of silica-based micro/nanoparticles are initially discussed, followed by detailed introduction on their US-based theranostic applications...
August 10, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28795419/simultaneous-mr-thermometry-and-acoustic-radiation-force-imaging-using-interleaved-acquisition
#15
Joshua T de Bever, Henrik Odéen, Lorne W Hofstetter, Dennis L Parker
PURPOSE: A novel and practical method for simultaneously performing MR acoustic radiation force imaging (ARFI) and proton resonance frequency (PRF)-shift thermometry has been developed and tested. This could be an important tool for evaluating the success of MR-guided focused ultrasound procedures for which MR-thermometry measures temperature and thermal dose and MR-ARFI detects changes in tissue mechanical properties. METHODS: MR imaging was performed using a gradient recalled echo segmented echo-planar imaging pulse sequence with bipolar motion encoding gradients (MEG)...
August 10, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28795293/endoscopic-palliation-of-pancreatic-cancer
#16
REVIEW
Vishal B Gohil, Jason B Klapman
Pancreas cancer is a fourth-leading cause of cancer death in the USA and its incidence is rising as the population is aging. The majority of patients present at an advanced stage due to the silent nature of the disease and treatment have focused more on palliation than curative intent. Gastroenterologists have become integral in the multidisciplinary care of these patients with a focus on providing endoscopic palliation of pancreas cancer. The three most common areas that gastroenterologists palliate endoscopically are biliary obstruction, cancer-related pain, and gastric outlet obstruction...
August 9, 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28794877/effects-of-hifu-induced-cavitation-on-flooded-lung-parenchyma
#17
Frank Wolfram, Georg Dietrich, Carsten Boltze, Klaus Vitold Jenderka, Thomas Günther Lesser
BACKGROUND: High intensity focused ultrasound (HIFU) has gained clinical interest as a non-invasive local tumour therapy in many organs. In addition, it has been shown that lung cancer can be targeted by HIFU using One-Lung Flooding (OLF). OLF generates a gas free saline-lung compound in one lung wing and therefore acoustic access to central lung tumours. It can be assumed that lung parenchyma is exposed to ultrasound intensities in the pre-focal path and in cases of misguiding. If so, cavitation might be induced in the saline fraction of flooded lung and cause tissue damage...
2017: Journal of Therapeutic Ultrasound
https://www.readbyqxmd.com/read/28791228/management-of-bladder-neck-stenosis-and-urethral-stricture-and-stenosis-following-treatment-for-prostate-cancer
#18
REVIEW
Helen L Nicholson, Yasser Al-Hakeem, Javier J Maldonado, Vincent Tse
The aim of this review is to examine all urethral strictures and stenoses subsequent to treatment for prostate cancer, including radical prostatectomy (RP), radiotherapy, high intensity focused ultrasound (HIFU) and cryotherapy. The overall majority respond to endoscopic treatment, including dilatation, direct visual internal urethrotomy (DVIU) or bladder neck incision (BNI). There are adjunct treatments to endoscopic management, including injections of corticosteroids and mitomycin C (MMC) and urethral stents, which remain controversial and are not currently mainstay of treatment...
July 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28789857/transcranial-ultrasonic-stimulation-modulates-single-neuron-discharge-in-macaques-performing-an-antisaccade-task
#19
Nicolas Wattiez, Charlotte Constans, Thomas Deffieux, Pierre M Daye, Mickael Tanter, Jean-François Aubry, Pierre Pouget
BACKGROUND: Low intensity transcranial ultrasonic stimulation (TUS) has been demonstrated to non-invasively and transiently stimulate the nervous system. Although US neuromodulation has appeared robust in rodent studies, the effects of US in large mammals and humans have been modest at best. In addition, there is a lack of direct recordings from the stimulated neurons in response to US. Our study investigates the magnitude of the US effects on neuronal discharge in awake behaving monkeys and thus fills the void on both fronts...
July 26, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28783627/post-hoc-analysis-of-passive-cavitation-imaging-for-classification-of-histotripsy-induced-liquefaction-in-vitro
#20
Kenneth B Bader, Kevin J Haworth, Adam D Maxwell, Christy K Holland
Histotripsy utilizes focused ultrasound to generate bubble clouds for transcutaneous tissue liquefaction. Image guidance of histotripsy pulses is required to provide spatially resolved monitoring of treatment progress. The aim of this study was to investigate the feasibility of plane wave B-mode and passive cavitation images to be used as binary classifiers of histotripsy-induced liquefaction. Prostate tissue phantoms were exposed to mechanically ablative histotripsy pulses over a range of pulse durations (5 - 20 μs) and peak negative pressures (12 - 23 MPa)...
August 2, 2017: IEEE Transactions on Medical Imaging
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