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https://www.readbyqxmd.com/read/28539532/relationship-between-sociability-toward-humans-and-physiological-stress-in-dogs
#1
Yoon-Joo Shin, Nam-Shik Shin
Sociability is an essential trait for dogs to successfully interact with humans. In this study, the relationship between sociability and physiological stress was examined. Additionally, whether differences exist between companion dogs (C group) and shelter dogs (S group) was examined. Overall, healthy 37 dogs (C group=21 and S group=16) were examined. After 5 min of walking, the dog and the owner (or the chief manager) rested freely in the experimental location for 5 min. The behavioral test with 6 categories was conducted to evaluate sociability over 4 min...
May 25, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28534468/effect-of-wearing-a-telemetry-jacket-on-behavioral-and-physiologic-parameters-of-dogs-in-the-open%C3%A2-field-test
#2
Richard E Fish, Melanie L Foster, Margaret E Gruen, Barbara L Sherman, David C Dorman
Safety pharmacology studies in dogs often integrate behavioral assessments made using video recording with physiologicmeasurements collected by telemetry. However, whether merely wearing the telemetry vest affects canine behavior and otherparameters has not been evaluated. This pilot study assessed the effect of a telemetry vest on behavioral and physiologic responses to an environmental stressor, the sounds of a thunderstorm, in Labrador retrievers. Dogs were assigned to one of 2 experimental groups (Vest and No-Vest, n = 8 dogs per group) by using a matched pairs design, with a previously determined,sound-associated anxiety score as the blocking variable...
May 22, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28520773/development-of-the-highly-sensitive-dog-questionnaire-to-evaluate-the-personality-dimension-sensory-processing-sensitivity-in-dogs
#3
Maya Braem, Lucy Asher, Sibylle Furrer, Isabel Lechner, Hanno Würbel, Luca Melotti
In humans, the personality dimension 'sensory processing sensitivity (SPS)', also referred to as "high sensitivity", involves deeper processing of sensory information, which can be associated with physiological and behavioral overarousal. However, it has not been studied up to now whether this dimension also exists in other species. SPS can influence how people perceive the environment and how this affects them, thus a similar dimension in animals would be highly relevant with respect to animal welfare. We therefore explored whether SPS translates to dogs, one of the primary model species in personality research...
2017: PloS One
https://www.readbyqxmd.com/read/28505349/decline-of-ecological-functions-performed-by-dung-beetles-in-areas-of-atlantic-forest-and-contribution-of-rollers-and-tunnellers-in-organic-matter-removal
#4
M Batilani-Filho, M I M Hernandez
The feeding behavior of the Scarabaeinae subfamily has positive implications on ecosystem functioning. We characterize the necrophagous and coprophagous dung beetle assemblages, and we quantify the removal of swine carrion and domestic dog dung in two areas with different degrees of environmental disturbance in an Atlantic Forest remnant located in Florianopolis, SC, Brazil. The experiment was setup at eight sampling points in each area, by installing one control and two collection and removal assessment arenas for collecting necrophagous dung beetles while simultaneously evaluating the removal of carrion (50 g of rotting pork for 48 h)...
May 12, 2017: Environmental Entomology
https://www.readbyqxmd.com/read/28503035/current-trends-in-canine-problem-solving-and-cognition
#5
Ádám Miklósi, Enikő Kubinyi
Dogs have occupied a central place in modern comparative cognition, partly because of their specific past and present relationship with humans. Over the years, we have gained insights about the functioning of the dog's mind, which has helped us to understand how dogs' problem-solving abilities differ from those present in related species such as the wolf. Novel methodologies are also emerging that allow for the study of neural and genetic mechanisms that control mental functions. By providing an overview from an ethological perspective, we call for greater integration of the field and a better understanding of natural dog behavior as a way to generate scientific hypotheses...
October 1, 2016: Current Directions in Psychological Science
https://www.readbyqxmd.com/read/28501556/behavioral-and-physiological-reactions-in-dogs-to-a-veterinary-examination-owner-dog-interactions-improve-canine-well-being
#6
Erika Csoltova, Michaël Martineau, Alain Boissy, Caroline Gilbert
In order to improve well-being of dogs during veterinary visits, we aimed to investigate the effect of human social interactions on behavior and physiology during routine examination. Firstly, we assessed the impact of a standardized veterinary examination on behavioral and physiological indicators of stress in dogs. Secondly, we examined whether the owner's tactile and verbal interactions with the dog influenced behavioral and physiological stress-associated parameters. A randomized within-subjects crossover design was used to examine behavior (n=33), rectal temperature (n=33), heart rate (HR) (n=18), maximal ocular surface temperature (max OST) (n=13) and salivary cortisol concentrations (n=10) in healthy privately owned pet dogs...
May 10, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28495701/poor-human-olfaction-is-a-19th-century-myth
#7
REVIEW
John P McGann
It is commonly believed that humans have a poor sense of smell compared to other mammalian species. However, this idea derives not from empirical studies of human olfaction but from a famous 19th-century anatomist's hypothesis that the evolution of human free will required a reduction in the proportional size of the brain's olfactory bulb. The human olfactory bulb is actually quite large in absolute terms and contains a similar number of neurons to that of other mammals. Moreover, humans have excellent olfactory abilities...
May 12, 2017: Science
https://www.readbyqxmd.com/read/28495196/pharmacokinetics-of-a-novel-spot-on-formulation-of-praziquantel-for-dogs
#8
María Laura Gutiérrez, Guillermo Di Federico, Jorge A Dale, Juan M Minoia, Carlos D Corrales, Paula Schaiquevich, Silvia Wikinski
Praziquantel (PZQ) is an anthelmintic drug used both in humans and animals that can be administered through various routes. There are transdermal formulations for cats, but only oral or subcutaneous dosage forms for dogs. Given the fact that the cat's skin and the dog's skin have different characteristics, which in turn affect bioavailability, we developed a PZQ spot-on formulation for dogs. This study was aimed at determining the plasmatic behavior of topically administered PZQ (Labyes(®)) in adult dogs. Dogs were administered PZQ (14...
May 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28494924/loss-of-cd45-cell-surface-expression-in-canine-t-zone-lymphoma-results-from-reduced-gene-expression
#9
V Martini, M Cozzi, A Aricò, G Dalla Rovere, A Poggi, F Albonico, M Mortarino, E Ciusani, L Aresu, S Comazzi
Canine T-zone lymphoma (TZL) is a peculiar lymphoma subtype characterized by an indolent clinical course and aberrant CD45-negative phenotype, commonly recognized by flow cytometry (FC). Recent studies have described clinical presentation and behavior, but to date the mechanisms behind the loss of CD45 protein expression have never been investigated. The aims of this study were: 1) to confirm the absence of CD45 in canine TZL via the concomitant use of FC and immunohistochemistry with two different sources of antibody; and 2) to investigate the amount of CD45 transcript and the presence of CD45 gene in the neoplastic cells of dogs affected by TZL...
May 2017: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/28494701/spindle-cell-lipoma-in-dogs
#10
Giancarlo Avallone, Valeria Pellegrino, Luisa V Muscatello, Giuseppe Sarli, Paola Roccabianca
Spindle cell lipoma (SCL) is a benign neoplasm of the adipose tissue that may resemble an undifferentiated soft tissue sarcoma (STS). This report describes the histopathological features of 6 SCLs in dogs. All SCLs were located in the subcutis and were composed of bland, occasionally vacuolated spindle cells intermixed with ropey collagen and myxoid matrix. Sudan IV stain performed in 1 case demonstrated the lipid content of vacuoles. Mature adipocytes represented less than 10% of the neoplasm in 3 cases and were absent in the remaining 3...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28493759/-characterizing-autism-relevant-social-behavior-in-poodles-canis-familiaris-via-owner-report-correction-to-zamzow-et-al-2017
#11
(no author information available yet)
Reports an error in "Characterizing Autism-Relevant Social Behavior in Poodles via Owner Report" by Rachel M. Zamzow, Lisa Lit, Shelley Hamilton and David Q. Beversdorf (Journal of Comparative Psychology, Advanced Online Publication, Mar 13, 2017, np). In the article, the scientific name for the species was missing in the title. All versions of this article have been corrected. (The following abstract of the original article appeared in record 2017-11247-001.) Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by deficits in social communication and the presence of restricted, repetitive behaviors...
May 2017: Journal of Comparative Psychology
https://www.readbyqxmd.com/read/28487862/naturally-occurring-canine-invasive-urinary-bladder-cancer-a-complementary-animal-model-to-improve-the-success-rate-in-human-clinical-trials-of-new-cancer-drugs
#12
REVIEW
Christopher M Fulkerson, Deepika Dhawan, Timothy L Ratliff, Noah M Hahn, Deborah W Knapp
Genomic analyses are defining numerous new targets for cancer therapy. Therapies aimed at specific genetic and epigenetic targets in cancer cells as well as expanded development of immunotherapies are placing increased demands on animal models. Traditional experimental models do not possess the collective features (cancer heterogeneity, molecular complexity, invasion, metastasis, and immune cell response) critical to predict success or failure of emerging therapies in humans. There is growing evidence, however, that dogs with specific forms of naturally occurring cancer can serve as highly relevant animal models to complement traditional models...
2017: International Journal of Genomics
https://www.readbyqxmd.com/read/28480612/pharmacological-and-toxicological-study-of-maytenus-ilicifolia-leaf-extract-part-i-preclinical-studies
#13
Ricardo Tabach, Joaquim M Duarte-Almeida, Elisaldo A Carlini
One of the Brazilians medicinal plants most cited in ethnopharmacological surveys for the treatment of ulcers and gastric diseases was evaluated for its efficacy and toxicity. Maytenus ilicifolia leaf extract (MIE) was acutely and chronically (180 days) administered to rats, mice, and dogs. Acute tests were antiulcer effect and toxicological trials (observational pharmacological screening, LD50, motor coordination, sleeping time and motor activity). Chronic tests were the following: weight gain/loss and behavioral parameters in rats and mice; estrus cycle, effects on fertility, and teratogenic studies in rats and mutagenic features in mice, in addition to the Ames and micronucleus test...
May 8, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28475209/the-relationship-between-direct-predation-and-antipredator-responses-a-test-with-multiple-predators-and-multiple-prey
#14
Scott Creel, Egil Dröge, Jassiel M'soka, Daan Smit, Matt Becker, Dave Christianson, Paul Schuette
Most species adjust their behavior to reduce the likelihood of predation. Many experiments have shown that antipredator responses carry energetic costs that can affect growth, survival and reproduction, so that the total cost of predation depends on a trade-off between direct predation and risk effects. Despite these patterns, few field studies have examined the relationship between direct predation and the strength of antipredator responses, particularly for complete guilds of predators and prey. We used scan sampling in 344 observation periods over a four-year field study to examine behavioral responses to the immediate presence of predators for a complete antelope guild (dominated by wildebeest, zebra and oribi) in Liuwa Plains National Park, testing for differences in response to all large carnivores in the ecosystem (lions, spotted hyenas, cheetahs and African wild dogs)...
May 5, 2017: Ecology
https://www.readbyqxmd.com/read/28454849/synthesis-and-biological-evaluation-of-novel-selective-androgen-receptor-modulators-sarms-part-iii-discovery-of-4-5-oxopyrrolidine-1-yl-benzonitrile-derivative-2f-as-a-clinical-candidate
#15
Katsuji Aikawa, Moriteru Asano, Koji Ono, Noriyuki Habuka, Jason Yano, Keith Wilson, Hisashi Fujita, Hitoshi Kandori, Takahito Hara, Megumi Morimoto, Takashi Santou, Masuo Yamaoka, Masaharu Nakayama, Atsushi Hasuoka
We previously reported that 4-(pyrrolidin-1-yl)benzonitrile derivative 1b was a selective androgen receptor modulator (SARM) that exhibited anabolic effects on organs such as muscles and the central nervous system (CNS), but neutral effects on the prostate. From further modification, we identified that 4-(5-oxopyrrolidine-1-yl)benzonitrile derivative 2a showed strong AR binding affinity with improved metabolic stabilities. Based on these results, we tried to enhance the AR agonistic activities by modifying the substituents of the 5-oxopyrrolidine ring...
April 13, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/28448889/studies-on-the-metabolites-difference-of-psoralen-isopsoralen-in-human-and-six-mammalian-liver-microsomes-in-vitro-by-uhplc-ms-ms
#16
Aihong Yang, Junxiu Chen, Yetao Ma, Lili Wang, Yaowen Fan, Xin He
Psoralen and isopsoralen are found in many fruits, vegetables and traditional Chinese medicines (TCM), such as Ficus carica L., Celery, Fructus Psoraleae etc. Modern pharmacological studies found that psoralen and isopsoralen can show estrogen-like activity, antitumor, and antibacterial activities etc. However, some research results also show some liver damage associated with the use of psoralen/isopsoralen or related medicines in human. Many studies focus on the pharmacological activities of psoralen/isopsoralen, while it is important to choose the suitable pharmacological models which are relevant to human in drug metabolism and pharmacokinetic process...
April 20, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28446072/the-influence-of-force-direction-on-the-fracture-pattern-and-fracture-resistance-of-canine-teeth-in-dogs
#17
Stephanie Goldschmidt, Catherine Zimmerman, Caitlyn Collins, Scott Hetzel, Heidi-Lynn Ploeg, Jason W Soukup
Biomechanical studies of the elongated canine tooth of animals are few, and thus our understanding of mechanical and physical properties of animal teeth is limited. The objective of the present study was to evaluate the influence of force direction on fracture resistance and fracture pattern of canine teeth in an ex vivo dog cadaver model. Forty-five extracted canine teeth from laboratory beagle dogs were standardized by hard tissue volume and randomly distributed among 3 force direction groups. The teeth were secured within a universal testing machine and a load was applied at different directions based on testing group...
January 1, 2017: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/28444161/odor-perception-by-dogs-evaluating-two-training-approaches-for-odor-learning-of-sniffer-dogs
#18
Carola Fischer-Tenhagen, Dorothea Johnen, Wolfgang Heuwieser, Roland Becker, Kristin Schallschmidt, Irene Nehls
In this study, a standardized experimental set-up with various combinations of herbs as odor sources was designed. Two training approaches for sniffer dogs were compared; first, training with a pure reference odor, and second, training with a variety of odor mixtures with the target odor as a common denominator. The ability of the dogs to identify the target odor in a new context was tested. Six different herbs (basil, St. John's wort, dandelion, marjoram, parsley, ribwort) were chosen to produce reference materials in various mixtures with (positive) and without (negative) chamomile as the target odor source...
June 1, 2017: Chemical Senses
https://www.readbyqxmd.com/read/28443682/abandonment-of-dogs-and-cats-public-opinions-as-population-management-indicators
#19
Oswaldo Santos Baquero, Evelyn Nestori Chiozzotto, Rita de Cassia Maria Garcia, Marcos Amaku, Fernando Ferreira
This study involved characterizing public opinions on selected issues related to the abandonment of dogs and cats in Votorantim, São Paulo, Brazil. This goal was achieved by applying multiple correspondence analysis to answers recorded in questionnaires of a population-based survey. The results suggest that the tolerance of potentially problematic behaviors did not depend on the specific kind of behavior, at least among the behaviors evaluated. The opinions given for the most frequent fate of the companion animals did not depend on the species, and those who considered abandonment to be one of the most frequent fates tended to also consider abandonment as a solution to problematic behaviors...
July 2017: Journal of Applied Animal Welfare Science: JAAWS
https://www.readbyqxmd.com/read/28443051/social-behavior-of-pet-dogs-is-associated-with-peripheral-oxtr-methylation
#20
Giulia Cimarelli, Zsófia Virányi, Borbála Turcsán, Zsolt Rónai, Mária Sasvári-Székely, Zsófia Bánlaki
Oxytocin is a key modulator of emotional processing and social cognitive function. In line with this, polymorphisms of genes involved in oxytocin signaling, like the oxytocin receptor (OXTR) gene, are known to influence social behavior in various species. However, to date, no study has investigated environmental factors possibly influencing the epigenetic variation of the OXTR gene and its behavioral effects in dogs. Pet dogs form individualized and strong relationships with their owners who are central figures in the social environment of their dogs and therefore might influence the methylation levels of their OXTR gene...
2017: Frontiers in Psychology
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