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Platelet rich fibrin

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https://www.readbyqxmd.com/read/28635382/white-cell-and-platelet-content-affects-the-release-of-bioactive-factors-in-different-blood-derived-scaffolds
#1
S Cabaro, V D'Esposito, R Gasparro, F Borriello, F Granata, G Mosca, F Passaretti, J C Sammartino, F Riccitiello, F Beguinot, P Formisano, G Sammartino
Platelet-derived factors are biomaterials that might accelerate healing process in oral, maxillofacial, and several other applications. Release of specific factors by platelet concentrates is critical to achieving a successful outcome. Here, we have shown that platelet-rich fibrin (PRF) clots were beneficial sources of leukocytes, which may directly affect the release of chemokines and growth factors. When compared with the standard leukocyte-PRF (L-PRF), the experimental low-force modified procedure [defined as advanced-PRF (A-PRF)] entrapped the same content of viable leukocytes, released a similar amount of inflammatory cytokines, but secreted 3-, 1...
June 21, 2017: Platelets
https://www.readbyqxmd.com/read/28622320/a-novel-graft-option-after-pterygium-excision-platelet-rich-fibrin-for-conjunctivoplasty
#2
H B Cakmak, G Dereli Can, M E Can, N Cagil
PurposeTo compare the surgical results, complications, and recurrence rates of primary pterygium excision with conjunctival autografts (CA) vs platelet-rich fibrin (PRF) grafts.Patients and methodsA total of 35 eyes of 35 patients with primary pterygium were included in the study. The patients underwent excision of pterygium followed by closure of the bare sclera by CA (group 1, n=20) vs PRF grafts (group 2, n=15). The PRF was generated from the patients' own whole-blood sample by centrifugation and pressing...
June 16, 2017: Eye
https://www.readbyqxmd.com/read/28610705/anastomotic-ulcers-in-short-bowel-syndrome-new-suggestions-from-a-multidisciplinary-approach
#3
Fabio Fusaro, Renato Tambucci, Erminia Romeo, Pietro Bagolan, Luigi Dall'Oglio, Stefano Ceccarelli, Paola Francalanci, Dominique Hermans, Andrea Pietrobattista, Antonella Diamanti, Filippo Torroni, Paola De Angelis
BACKGROUND AND AIMS: Anastomotic ulceration (AU) is a rare potential life-threatening complication that may occur after intestinal resection. The diagnosis is often delayed after a long-lasting history of refractory anemia. The pathogenesis remains unknown and there are no established therapies. The aim of the study was to analyze the medical history of children with short bowel syndrome (SBS) who were experiencing AU. METHODS: Records of SBS children were retrospectively reviewed...
June 3, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28596670/growth-factor-variation-in-two-types-of-autologous-platelet-biomaterials-prp-versus-prf
#4
Satyam Arora, Urvershi Kotwal, Mitu Dogra, Veena Doda
Autologous platelet biomaterials represent a key source of cytokines and growth factors extensively used for clinical and surgical applications involving tissue regeneration; wound healing and tissue repair. In this communication we discuss the growth factors released by activated platelet rich plasma (PRP) and platelet rich fibrin (PRF) releasate. Our study highlights that significantly higher growth factors (TGF-ß1) are released by activated PRP as compared to releasate of PRF. The various growth factors released by both platelet products are significantly higher than the baseline concentration in the whole blood and have different bio-mechanism hence should be individualized as per the clinical indication...
June 2017: Indian Journal of Hematology & Blood Transfusion
https://www.readbyqxmd.com/read/28596050/histological-evaluation-of-effectiveness-of-platelet-rich-fibrin-on-healing-of-sinus-membrane-perforations-a-preclinical-animal-study
#5
Ceyhun Aricioglu, Dogan Dolanmaz, Alparslan Esen, Kubilay Isik, Mustafa Cihat Avunduk
The aim of this study was to evaluate the effectiveness of platelet-rich fibrin (PRF) in repairing of Schneiderian membrane perforations in rabbit maxillary sinus. A total of 42 female New Zealand rabbits were randomly divided into two groups. Symmetrical bony defects were created 1 cm in diameter and the sinus membranes were exposed. The Schneiderian membranes were elevated in both sinuses and each membrane was perforated with a 1 cm incision. No treatment was applied to the right perforations in both groups...
May 15, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28590091/an-update-on-the-protocols-and-biologic-actions-of-platelet-rich-fibrin-in-dentistry
#6
Rucha Shah, Triveni M G, Raison Thomas, Dhoom Singh Mehta
Platelet rich fibrin (PRF) is a surgical biologic additive that is prepared by manipulation of autologous blood. It has now evolved to become one of the most widely used platelet concentrate in dentistry. It has almost replaced Platelet rich plasma (PRP) for usage owing to its advantages such as being 100% autogenous, easy technique, time and cost effectiveness, superior & prolonged growth factor release. It finds varied applications in dentistry including management of gingival recession, for guided bone regeneration in periodontal, peri-implant and endodontic bone defects...
June 2017: European Journal of Prosthodontics and Restorative Dentistry
https://www.readbyqxmd.com/read/28587096/the-effect-of-platelet-rich-fibrin-calcium-sulfate-hemihydrate-platelet-rich-plasma-and-resorbable-collagen-on-soft-tissue-closure-of-extraction-sites
#7
Lisa M Yerke, Amal Jamjoom, Talal M Zahid, Robert E Cohen
Rapid and complete soft tissue healing after tooth extraction minimizes surgical complications and facilitates subsequent implant placement. We used four treatment methods and assessed changes in soft tissue socket closure following tooth extraction in humans. The effects of platelet-rich fibrin-calcium sulfate hemihydrate (PRF-CSH), platelet-rich plasma-calcium sulfate hemihydrate (PRP-CSH), a resorbable collagen dressing (RCD), and no grafting material were compared in a randomized, controlled pilot study with a blinded parallel design (N = 23)...
May 25, 2017: Journal of Functional Biomaterials
https://www.readbyqxmd.com/read/28571302/successful-surgical-outcome-for-an-endodontic-failure-using-biodentine-tm-as-retrograde-restoration-in-conjunction-with-platelet-rich-fibrin-prf-for-progressive-healing
#8
Ajinkya Mansing Pawar, Suraj M Pawar, Bhagyashree Thakur, Sharad Kokate
No abstract text is available yet for this article.
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28571284/evaluation-of-periapical-healing-of-apicomarginal-defect-in-mandibular-first-molar-treated-with-platelet-rich-fibrin-a-case-report
#9
Jitesh Wadhwa, Alpa Gupta, Suruchi Hans
The presence of an apicomarginal defect is one of the reasons for the failure of endodontic treatment. The best treatment option to treat an apicomarginal defect is to perform endodontic surgery using Guided Tissue Regeneration (GTR) membranes. The present case report evaluated the healing of periapical lesion along with apicomarginal defect using Platelet Rich Fibrin (PRF) as membrane in periapical surgery of mandibular first molar. Recall examination was performed at 3 and 18 months post surgery. A satisfactory periapical healing was evident using PRF in apicomarginal defect of mandibular first molar...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28571267/effect-of-autologous-platelet-rich-fibrin-in-human-mandibular-molar-grade-ii-furcation-defects-a-randomized-clinical-trial
#10
Syed Asimuddin, Rekha Rani Koduganti, Veerendra Nath Reddy Panthula, Surya Prasanna Jammula, Rajashree Dasari, Himabindu Gireddy
INTRODUCTION: The Furcation of multirooted teeth is difficult region to gain access for treatment due to their complex anatomy. Modifications have been made in the periodontal instrument armamentarium to facilitate treatment of furcations. Moreover, many new materials have been introduced to attempt regeneration in the furcation defects. AIM: This study evaluated the role of Platelet Rich Fibrin (PRF) in comparison with allograft and Guided Tissue Regeneration (GTR) in the treatment of Grade II mandibular molar furcations...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28565782/hybrid-composites-of-mesenchymal-stem-cell-sheets-hydroxyapatite-and-platelet-rich-fibrin-granules-for-bone-regeneration-in-a-rabbit-calvarial-critical-size-defect-model
#11
Xi Wang, Guanghui Li, Jia Guo, Lei Yang, Yiming Liu, Qiang Sun, Rui Li, Weiwei Yu
The reconstruction of large bone defects remains a major clinical challenge, and tissue engineering is a promising technique for resolving this problem. Many attempts have been made to optimize bone tissue engineering protocols. The aim of the present study was to develop a process incorporating mesenchymal stem cell (MSC) sheets with nanoscale hydroxyapatite (nano-HA) and autologous platelet-rich fibrin (PRF) granules for enhanced bone formation within a critical-sized rabbit cranial defect. MSC sheets and PRF were prepared prior to in vivo experiments...
May 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28561191/platelet-rich-fibrin-conduits-as-an-alternative-to-nerve-autografts-for-peripheral-nerve-repair
#12
Felipe Roth, Marcela Fernandes, Sandra G Valente, João B G Santos, Rebeca Barros Furukawa, Carlos Henrique Fernandes, Vilnei M Leite, Flávio Faloppa
No abstract text is available yet for this article.
May 22, 2017: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/28560233/evolution-current-status-and-advances-in-application-of-platelet-concentrate-in-periodontics-and-implantology
#13
REVIEW
Amit Arvind Agrawal
Platelet concentrates (PC) [platelet-rich plasma (PRP) and platelet-rich fibrin (PRF)] are frequently used for surgical procedures in medical and dental fields, particularly in oral and maxillofacial surgery, plastic surgery and sports medicine. The objective of all these technologies is to extract all the elements from a blood sample that could be used to improve healing and promote tissue regeneration. Although leukocyte rich and leukocyte poor PRP's have their own place in literature, the importance of non-platelet components in a platelet concentrate remains a mystery...
May 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28555210/report-of-a-jaw-osteonecrosis-possibly-caused%C3%A2-by-denosumab
#14
Daniel Saad, Patrick Saad
PURPOSE: To report a case of osteonecrosis of the jaw (ONJ) occurring in an implant area possibly related to denosumab, a relatively new antiosteoporotic agent. MATERIALS AND METHODS: Two months following the extraction of both maxillary first molars, a bilateral maxillary sinus floor elevation was performed on a 64-year-old female patient under a biannual 
60 mg denosumab antiosteoporotic treatment. Seven months later, two implants were inserted in a single-stage procedure in each of the grafted sinuses...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28551729/use-of-platelet-rich-fibrin-in-regenerative-dentistry-a-systematic-review
#15
REVIEW
Richard J Miron, Giovanni Zucchelli, Michael A Pikos, Maurice Salama, Samuel Lee, Vincent Guillemette, Masako Fujioka-Kobayashi, Mark Bishara, Yufeng Zhang, Hom-Lay Wang, Fatiha Chandad, Cleopatra Nacopoulos, Alain Simonpieri, Alexandre Amir Aalam, Pietro Felice, Gilberto Sammartino, Shahram Ghanaati, Maria A Hernandez, Joseph Choukroun
OBJECTIVES: Research across many fields of medicine now points towards the clinical advantages of combining regenerative procedures with platelet-rich fibrin (PRF). This systematic review aimed to gather the extensive number of articles published to date on PRF in the dental field to better understand the clinical procedures where PRF may be utilized to enhance tissue/bone formation. MATERIALS AND METHODS: Manuscripts were searched systematically until May 2016 and separated into the following categories: intrabony and furcation defect regeneration, extraction socket management, sinus lifting procedures, gingival recession treatment, and guided bone regeneration (GBR) including horizontal/vertical bone augmentation procedures...
July 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28550856/platelet-rich-fibrin-might-not-provide-a-benefit-in-healing-and-complications-after-third-molar-extraction
#16
Romina Brignardello-Petersen
No abstract text is available yet for this article.
June 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28550846/platelet-rich-fibrin-membrane-does-not-improve-clinical-outcomes-compared-with-other%C3%A2-treatment-modalities-in-the-treatment-of-gingival-recession
#17
Yumi Ogata, Yong Hur
No abstract text is available yet for this article.
June 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28545565/the-combination-of-nano-calcium-sulfate-platelet-rich-plasma-gel-scaffold-with-bmp2-gene-modified-mesenchymal-stem-cells-promotes-bone-regeneration-in-rat-critical-sized-calvarial-defects
#18
Zunpeng Liu, Xue Yuan, Gabriela Fernandes, Rosemary Dziak, Ciprian N Ionita, Chunyi Li, Changdong Wang, Shuying Yang
BACKGROUND: Mesenchymal stem cells (MSCs) can be differentiated into an osteoblastic lineage in the presence of growth factors (GFs). Platelet-rich plasma (PRP), which can be easily isolated from whole blood, contains a large amount of GFs, and, therefore, promotes bone growth and regeneration. The main goal of this work was to develop and investigate the effect of a new sandwich-like bone scaffold which combines a nano-calcium sulfate (nCS) disc along with PRP fibrin gel (nCS/PRP) with BMP2-modified MSCs on bone repair and regeneration in rat critical-sized calvarial defects...
May 25, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28529414/comparison-of-efficacy-of-autologous-platelet-rich-fibrin-versus-saline-dressing-in-chronic-venous-leg-ulcers-a-randomised-controlled-trial
#19
Anirudh Somani, Reena Rai
BACKGROUND: Venous leg ulcer is a chronic condition, and various treatment modalities are available. Platelet-rich fibrin (PRF) is one of the newer modalities and it contains fibroblast growth factor (GF), vascular endothelial GF, angiopoitin and platelet-derived GF which enhances the wound healing. Hence, we conducted a randomised controlled trial to compare the efficacy of PRF versus saline dressing in chronic venous leg ulcers. AIM: This study aims to compare the efficacy of autologous PRF with saline dressing in patients with chronic venous leg ulcer and to compare the mean reduction in ulcer area at the end of 4 weeks...
January 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28529413/autologous-platelet-rich-fibrin-matrix-in-non-healing-trophic-ulcers-in-patients-with-hansen-s-disease
#20
Umashankar Nagaraju, Priya K Sundar, Priyanka Agarwal, Belliappa P Raju, Mahesh Kumar
BACKGROUND: Non-healing trophic ulcers in Hansen's disease patients is one of the major causes for disability. It has been shown that autologous platelet-rich fibrin matrix (PRFM) is effective in healing chronic non-healing leg ulcers. AIM: The objective of this study is to demonstrate the efficacy of autologous platelet-rich fibrin matrix (PRFM) in non-healing trophic ulcers in patients treated for Hansen's disease. DESIGN: A prospective study...
January 2017: Journal of Cutaneous and Aesthetic Surgery
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