keyword
MENU ▼
Read by QxMD icon Read
search

Pulmonary nodule

keyword
https://www.readbyqxmd.com/read/29053224/programmed-death-ligand-1-testing-of-lung-cancer-cytology-specimens-obtained-with-bronchoscopy
#1
Sean P Stoy, Lauren Rosen, Jeffrey Mueller, Septimiu Murgu
BACKGROUND: Programmed death-ligand 1 (PD-L1) expression testing is recommended by guidelines for patients with advanced non-small cell lung cancer (NSCLC). The primary objective of the current study was to determine the success rate of PD-L1 testing from cytology cell block samples obtained by bronchoscopic needle aspiration. The secondary objective was the assessment of the difference in specimen adequacy acquired via needles of different gauges. METHODS: Patients with NSCLC who underwent bronchoscopic needle aspirations for which PD-L1 testing was requested between November 1, 2016, and February 6, 2017, were included in the current analysis...
October 20, 2017: Cancer
https://www.readbyqxmd.com/read/29053106/issues-in-quantification-of-registered-respiratory-gated-pet-ct-in-the-lung
#2
Vesna Cuplov, Beverley Fiona Holman, Jamie R McClelland, Marc Modat, Brian F Hutton, Kris Thielemans
PET/CT quantification of lung tissue is limited by several difficulties: the lung density and local volume changes during respiration, the anatomical mismatch between PET and CT and the relative contributions of tissue, air and blood to the PET signal (the tissue fraction effect). Air Fraction Correction (AFC) has been shown to improve PET image quantification in the lungs. Methods to correct for the movement and anatomical mismatch involve respiratory gating and image registration techniques. While conventional registration methods only account for spatial mismatch, the Jacobian determinant of the deformable registration transformation field can be used to estimate local volume changes and could therefore potentially be used to correct (i...
October 20, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29052351/analysis-of-the-clinical-features-of-invasive-bronchopulmonary-aspergillosis
#3
Yueqin Cao, Changzhou Shao, Yuanlin Song
INTRODUCTION: Early diagnosis of invasive bronchopulmonary aspergillosis (IBPA) is difficult, so the mortality rate is high. OBJECTIVE: To discuss the clinical features of IBPA. METHODS: We retrospectively analyzed the clinical features, imaging findings, laboratory test, diagnosis, and treatment of 115 patients with IBPA diagnosed from October 2004 to June 2013 in Zhongshan Hospital, Fudan University. RESULTS: The main clinical manifestations were cough in 58 patients (50...
October 20, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29050127/-immune-related-pneumonitis-caused-by-programmed-death-1-inhibitor-pembrolizumab-a-case-report-and-literature-review
#4
Y L Chen, J Zhao, R Jia, H Y Wang, J Zheng, C Q Bai, M Z Wang, J M Xu
Objective: To investigate the risk factors, clinical manifestations, radiological features, diagnosis, treatment and prognosis of immune-related pneumonitis caused by programmed death-1(PD-1)/PD-L1 inhibitors. Methods: The clinical data of immune-related pneumonitis caused by PD-1 inhibitor Pembrolizumab in a patient with advanced esophageal carcinoma admitted to the 307(th) Hospital of Chinese People's Liberation Army was retrospectively analyzed and the related literatures were reviewed. We searched Medline database using the keywords"PD-1 inhibitor","PD-L1 inhibitor","Pembrolizumab","Nivolumab","Atezolizumab"combined with"Pneumonitis"by Mar 31, 2017...
October 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29049837/clinical-application-of-projection-mapping-technology-for-surgical-resection-of-lung-metastasis
#5
Toyofumi F Chen-Yoshikawa, Etsuro Hatano, Atsushi Yoshizawa, Hiroshi Date
Indocyanine green fluorescent image-guided surgery was developed to identify primary and metastatic nodules of various malignancies. However, currently, surgeons need to identify the fluorescent image on a monitor, which impedes surgical procedures. Herein, we developed a novel projection mapping device that can cast the real-time fluorescent image onto the surface of the targeted organ. We performed surgical resection of a lung metastasis of hepatoblastoma using this technique. The projection mapping technique clearly detected the pulmonary lesion, and no other lesions were identified in the ipsilateral thorax...
July 28, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049613/hybrid-operating-room-dyna-computed-tomography-combined-image-guided-electromagnetic-navigation-bronchoscopy-dye-marking-and-hookwire-localization-video-assisted-thoracic-surgery-metastasectomy
#6
Calvin S H Ng, Cheuk Man Chu, Cheuk Kin Lo, Rainbow W H Lau
Hybrid operating room Dyna-computed tomography imaging is increasingly recognized as an important adjunct for management of small pulmonary lesions, either for biopsy or for localization to guide surgical resection. We describe for the first time the combined hybrid operating room Dyna-computed tomography image-guided electromagnetic navigation bronchoscopy dye marking and hookwire localization approach to localize multiple sub-centimetre nodules for video-assisted thoracic surgery metastasectomy. Furthermore, such complex set of procedures can be safely and effectively performed within one operating environment, maximizing work efficiency and minimizing the potential for complications...
September 27, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049243/rare-case-of-pulmonary-lymphomatoid-granulomatosis-in-conjunction-with-tuberculosis-a-case-report
#7
Young Woo Ha, Chul Hwan Kim, Yong Park, Jang Wook Sohn, Min Ja Kim, Young Kyung Yoon
RATIONALE: Lymphomatoid granulomatosis is a very rare Epstein-Barr virus-driven lymphoproliferative disease. This disease has high mortality owing to its low incidence in conjunction with nonspecific presentations, which contribute to delays in diagnosis. PATIENT: An 87-year-old male had a week-long history of intermittent fever and general weakness. A chest radiograph showed multifocal patchy consolidations with nodular lesions. DIAGNOSES: Open lung biopsy using video-assisted thoracic surgery resulted in a diagnosis of grade III lymphomatoid granulomatosis...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29049239/clinical-features-and-diagnosis-of-chronic-pulmonary-aspergillosis-in-chinese-patients
#8
Xiaomeng Hou, Hong Zhang, Lei Kou, Wei Lv, Jingjing Lu, Ji Li
Chronic pulmonary aspergillosis (CPA) has recently been recognized as a significant global health burden. In China, the diagnosis of CPA is still unfamiliar to most doctors. The aim of this study was to demonstrate the clinical manifestations and diagnoses of CPA in China.A multidisciplinary team of doctors retrospectively screened 690 records of patients diagnosed with pulmonary aspergillosis from January 2000 to December 2016 at Peking Union Medical College Hospital, Beijing, China. Of these, 69 patients were diagnosed with CPA...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29047033/characterization-of-pulmonary-nodules-based-on-features-of-margin-sharpness-and-texture
#9
José Raniery Ferreira, Marcelo Costa Oliveira, Paulo Mazzoncini de Azevedo-Marques
Lung cancer is the leading cause of cancer-related deaths in the world, and one of its manifestations occurs with the appearance of pulmonary nodules. The classification of pulmonary nodules may be a complex task to specialists due to temporal, subjective, and qualitative aspects. Therefore, it is important to integrate computational tools to the early pulmonary nodule classification process, since they have the potential to characterize objectively and quantitatively the lesions. In this context, the goal of this work is to perform the classification of pulmonary nodules based on image features of texture and margin sharpness...
October 18, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/29038933/volume-doubling-time-of-lung-cancer-detected-in-idiopathic-interstitial-pneumonia-comparison-with-that-in-chronic-obstructive-pulmonary-disease
#10
Cherry Kim, Sang Min Lee, Jooae Choe, Eun Jin Chae, Kyung-Hyun Do, Joon Beom Seo
OBJECTIVES: To assess the volume doubling time (VDT) of lung cancers in IIP compared with COPD. METHODS: A total of 61 patients (32 with IIP and 29 with COPD) were identified. A radiologist performed three-dimensional manual segmentation for lung cancers. VDTs were calculated and compared between two groups. Logistic regression was performed to identify factors associated with rapid tumour growth (VDT < 90 days). RESULTS: The median VDT of lung cancers in IIP (78...
October 16, 2017: European Radiology
https://www.readbyqxmd.com/read/29036877/a-hybrid-cnn-feature-model-for-pulmonary-nodule-malignancy-risk-differentiation
#11
Huafeng Wang, Tingting Zhao, Lihong Connie Li, Haixia Pan, Wanquan Liu, Haoqi Gao, Fangfang Han, Yuehai Wang, YiFang Qi, Zhengrong Liang
The malignancy risk differentiation of pulmonary nodule is one of the most challenge tasks of computer-aided diagnosis (CADx). Most recently reported CADx methods or schemes based on texture and shape estimation have shown relatively satisfactory on differentiating the risk level of malignancy among the nodules detected in lung cancer screening. However, the existing CADx schemes tend to detect and analyze characteristics of pulmonary nodules from a statistical perspective according to local features only. Enlightened by the currently prevailing learning ability of convolutional neural network (CNN), which simulates human neural network for target recognition and our previously research on texture features, we present a hybrid model that takes into consideration of both global and local features for pulmonary nodule differentiation using the largest public database founded by the Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI)...
October 10, 2017: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/29035996/radioguided-occult-lesion-localization-technical-procedures-and-clinical-applications
#12
Gianpiero Manca, Sara Mazzarri, Domenico Rubello, Elisa Tardelli, Roberto C Delgado-Bolton, Francesco Giammarile, Manuela Roncella, Duccio Volterrani, Patrick M Colletti
PURPOSE: Regarding radioguided surgery, the concept of "radioguided occult lesion localization" (ROLL) is based on both preoperative interventional imaging and intraoperative radioguided detection of a clinically occult neoplastic lesion. METHODS: This methodology consists in the direct administration into the lesion of Tc-macroaggregated human albumin formed by relatively large particles retained at the injection site, which direct radioguided excisional biopsy...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29034693/role-of-18f-fdg-pet-ct-vs-ct-scan-in-patients-with-pulmonary-metastases-previously-operated-on-for-colorectal-liver-metastases
#13
Lopez Lopez Victor, Ricardo Robles, Roberto Brusadin, López-Conesa Asunción, Juan Torres, Domingo Perez Flores, Jose Luis Navarro, Pedro Jose Gil
BACKGROUND: There is currently no conclusive scientific evidence available regarding the role of the [18F]FDG PET/CT for detecting pulmonary metastases from colorectal cancer (PMCRC) in patients operated on for colorectal liver metastases (CRLM). In the follow up of patients who underwent surgery for CRLM, we compare CT-scan and [18F]FDG PET/CT in patients with PMCRC. METHODS: We designed the study prospectively performing an [18F]FDG PET/CT on all patients operated on for CRLM where the CT-scan detected PMCRC during the follow up...
October 15, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29033202/-pyopneumothorax-in-rheumatoid-arthritis
#14
B Huret, S Boulanger, L Benhamed, X Deprez, D Caparros
INTRODUCTION: Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting the joints but which frequently includes extra articular effects, including pulmonary nodules, which grow faster under immunosuppressive treatment. CASE REPORT: A 74 years old man, with mild asbestosis, underwent treatment with methotrexate then leflunomide (LEF) for seropositive RA. In February 2014, during monitoring of his asbestosis, chest CT scan showed the appearance of thick-walled cavitating lung nodules, with a central and sub pleural distribution...
October 12, 2017: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/29030294/type-i-interferon-pathway-activation-in-copa-syndrome
#15
Stefano Volpi, Jessica Tsui, Marcello Mariani, Claudia Pastorino, Roberta Caorsi, Oliviero Sacco, Angelo Ravelli, Anthony K Shum, Marco Gattorno, Paolo Picco
Mutations of the COPA gene cause an immune dysregulatory disease characterised by polyarticular arthritis and progressive interstitial lung disease with pulmonary haemorrhages. We report the case of a young girl that presented at age 3 with polyarticular arthritis, chronic cough and high titer rheumatoid factor. Radiologic imaging showed interstitial lung disease with tree-in-a-bud nodules and air-filled cysts. Targeted genetic analysis of COPA gene showed the reported c.698G>A mutation. The patient was lost to follow up for 3years during which therapy was discontinued with the development of joint damage and deformities...
October 10, 2017: Clinical Immunology: the Official Journal of the Clinical Immunology Society
https://www.readbyqxmd.com/read/29028153/tailored-intraoperative-localization-of-non-palpable-pulmonary-lesions-for-thoracoscopic-wedge-resection-using-hybrid-room-technology
#16
Alessia Stanzi, Federico Mazza, Francesco Lucio, Donatella Ghirardo, Maurizio Grosso, Alessandro Locatelli, Giulio Melloni
INTRODUCTION: VATS wedge resection can require conversion to thoracotomy when pulmonary lesions cannot be identified. Hybrid operating rooms (HOR) provide real-time image acquisition capabilities allowing the intraoperative placement of markers, to facilitate the removal of non-palpable nodules during VATS. OBJECTIVES: To present our workflow based on the alternative use of two different markers according to the location of the lung lesion, and report our initial results...
October 13, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29028090/a-comparative-study-on-inflammatory-factors-and-immune-functions-of-lung-cancer-and-pulmonary-ground-glass-attenuation
#17
C-Y Liu, W-G Xie, S Wu, J-W Tian, J Li
OBJECTIVE: To compare the inflammatory factors and immune functions of patients with lung cancer and pulmonary ground-glass attenuation. PATIENTS AND METHODS: A total of 108 patients with pulmonary sarcoidosis treated in our hospital were selected and randomly divided into lung cancer group (Group A, n=32), diffuse ground-glass nodule group (Group B, n=35) and solitary ground-glass nodule group (Group C, n=41) according to the diagnosis results. Levels of inflammatory factors, tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6) and interleukin-10 (IL-10), in serum were detected via enzyme-linked immunosorbent assay (ELISA); the T-lymphocyte subset levels (CD3+, CD4+, CD8+ and CD4+/CD8+) in the immune system of patients in the three groups were detected using the flow cytometer; the levels of immunoglobulins, immunoglobulin G (IgG), immunoglobulin A (IgA) and immunoglobulin M (IgM), were detected via immunoturbidimetric assay...
September 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29026982/severe-hemoptysis-associated-with-bacterial-pulmonary-infection-clinical-features-significance-of-parenchymal-necrosis-and-outcome
#18
Guillaume Carteaux, Damien Contou, Guillaume Voiriot, Antoine Khalil, Marie-France Carette, Martine Antoine, Antoine Parrot, Muriel Fartoukh
PURPOSE: Severe hemoptysis (SH) associated with non-tuberculosis bacterial lower respiratory tract infection (LRTI) is poorly described, and the efficacy of the usual decision-making process is unknown. This study aimed at describing the clinical, radiological patterns, mechanism, and microbiological spectrum of SH related to bacterial LRTI, and assessing whether the severity of hemoptysis and the results of usual therapeutic strategy are influenced by the presence of parenchymal necrosis...
October 12, 2017: Lung
https://www.readbyqxmd.com/read/29026608/diffuse-idiopathic-pulmonary-neuroendocrine-cell-hyperplasia-diagnosed-by-tranbronchoscopic-cryoprobe-biopsy-technique
#19
Ravi Patel, Carolina Collazo-Gonzalez, Arthur Andrews, Jean Johnson, Mark Rumbak, Maxwell Smith
Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) remains a poorly understood clinical entity. It is currently classified as a premalignant condition by the World Health Organization (WHO). Symptoms are similar to those associated with obstructive lung disease, including breathlessness and cough. The presentation is often initially ascribed to other diseases such as asthma or chronic obstructive pulmonary disease. Here, we present what we believe is the first described case of DIPNECH diagnosed by transbronchoscopic cryoprobe biopsy...
November 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/29026364/recurrent-pneumothoraces-in-a-patient-with-pulmonary-benign-metastasizing-leiomyoma
#20
Miranda Hann, Rinu Manacheril, Jerry St Pierre, Rajiv Gala
BACKGROUND: Pulmonary benign metastasizing leiomyoma (BML) is a rare disease with a malignant characteristic of spread from the uterus. Most cases are asymptomatic, and only 1% are associated with pneumothorax. CASE REPORT: We present the case of a 42-year-old female with recurrent pneumothoraces leading to an incidental finding of diffuse bilateral pulmonary nodules. The diagnosis of BML was based on the patient's history of uterine leiomyomata and confirmed by a biopsy showing benign smooth muscle staining for desmin and vimentin...
2017: Ochsner Journal
keyword
keyword
264
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"