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Pulmonary nodule

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https://www.readbyqxmd.com/read/29230956/prevalence-of-non-18-f-fluorodeoxyglucose-avid-incidental-findings-of-clinical-significance-on-whole-body-positron-emission-tomography-computed-tomography-a-review-of-500-consecutive-cases
#1
James A Sheldon, Kelvin K Yap, Kim L Taubman, Stephen M Schlicht
INTRODUCTION: The prevalence of incidental 18 F-fluorodeoxyglucose (FDG)-avid findings on positron emission tomography-computed tomography (PET/CT) has been extensively described. Few studies, however, have assessed the prevalence and significance of non-FDG-avid findings; pathology that is identified on review of the low-dose, non-contrast CT. The aim of this study was to determine the overall prevalence of non FDG-avid incidental findings on PET/CT and the prevalence of 'clinically significant' non FDG-avid pathology...
December 11, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29230286/asthma-mimic-case-report-and-literature-review-of-vocal-cord-nodule-associated-with-wheezing
#2
Muhammad Kashif, Tushi Singh, Ahsan Aslam, Misbahuddin Khaja
Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation. Various clinical conditions can mimic asthma, such as foreign body aspiration, subglottic stenosis, congestive heart failure, diffuse panbronchiolitis, aortic arch anomalies, reactive airway dysfunction syndrome, chronic obstructive pulmonary disease, retrosternal goiter, vocal cord tumors, other airway tumors, and vocal cord dysfunction. Upper airway obstruction can be a life-threatening emergency. Here, we present the case of a 58-year-old female with recurrent hospital visits for wheezing and exacerbations of asthma, who was later found to have a vocal cord nodule confirmed to be squamous cell carcinoma, which was mimicking like asthma...
2017: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29229107/clinical-characterization-of-52-patients-with-immunoglobulin-g4-related-disease-in-a-single-tertiary-center-in-japan-special-reference-to-lung-disease-in-thoracic-high-resolution-computed-tomography
#3
Takeshi Saraya, Kosuke Ohkuma, Masachika Fujiwara, Chika Miyaoka, Shoko Wada, Takayasu Watanabe, Sunao Mikura, Manami Inoue, Miku Oda, Mitsuru Sada, Yukari Ogawa, Kojiro Honda, Masaki Tamura, Takuma Yokoyama, Daisuke Kurai, Haruyuki Ishii, Hajime Takizawa
BACKGROUND: Immunoglobulin G4-related disease (IgG4-RD) is a rare multi-organ disorder. Physicians rarely encounter patients with IgG4-RD and its range of symptoms. METHODS: To elucidate the clinical characterization of IgG4-RD, along with the clinical significance of lung involvement, we retrospectively reviewed the medical records of patients who satisfied the comprehensive diagnostic criteria for IgG4-RD. RESULTS: We identified 52 patients with IgG4-RD...
November 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/29221316/recent-advances-in-the-management-of-pulmonary-tuberculoma-with-focus-on-the-use-of-tubeless-video-assisted-thoracoscopic-surgery
#4
REVIEW
Zhaohua Xia, Kun Qiao, Jianxing He
Pulmonary tuberculoma are benign solitary pulmonary nodules representing up to 25% of all resected solitary pulmonary nodules. However, the differentiation between pulmonary tuberculoma and lung cancer, as well as between active tuberculoma and inactive tuberculoma remains a clinical challenge. The present review summarizes the recent advances in the management of pulmonary tuberculoma, including radiological findings, the response to anti-tuberculosis treatment and surgical treatments. Application of the novel tubeless video-assisted thoracoscopic surgery (VATS) technique in both the diagnosis and treatment of pulmonary tuberculoma has been found to be safe and feasible and leads to less surgical trauma, which results in reduced length of hospitalization and better post-operative quality of life...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221313/video-assisted-thoracoscopic-surgery-vats-lower-lobe-bisegmentectomy-s7-8-for-a-central-pulmonary-metastasis
#5
Andreas Hiebinger, Thomas Weik, Horst Mertins, Johannes Bodner
Surgery for pulmonary metastasis is performed heterogeneously with regard to surgical approach [open vs. video-assisted thoracoscopic surgery (VATS)] and resection techniques (e.g., laser enucleation, electro-cautery resection, stapling). Complete tumor resection and preservation of lung parenchyma are of upmost importance. This is technically challenging, especially for central lesions close to vascular and bronchial segmental structures. Thus, simple thoracoscopic wedge resections are often not feasible. A VATS lower lobe bisegmentectomy (S7/8) was performed on a 62-year-old patient with a suspicious pulmonary nodule and a history of hemicolectomy for colorectal carcinoma...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221286/automatic-lung-rads%C3%A2-classification-with-a-natural-language-processing-system
#6
Sebastian E Beyer, Brady J McKee, Shawn M Regis, Andrea B McKee, Sebastian Flacke, Gilan El Saadawi, Christoph Wald
Background: Our aim was to train a natural language processing (NLP) algorithm to capture imaging characteristics of lung nodules reported in a structured CT report and suggest the applicable Lung-RADS™ (LR) category. Methods: Our study included structured, clinical reports of consecutive CT lung screening (CTLS) exams performed from 08/2014 to 08/2015 at an ACR accredited Lung Cancer Screening Center. All patients screened were at high-risk for lung cancer according to the NCCN Guidelines®...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29215824/pulmonary-histoplasmosis-identified-by-video-assisted-thoracic-surgery-vats-biopsy-a-case-report
#7
Ye Jin Lee, Hye Rin Kang, Jin Hwa Song, Sooim Sin, Sang Min Lee
Histoplasmosis is a common endemic mycosis in North, Central, and South America, but Korea is not known as an endemic area. We treated an immunocompetent Korean patient who had histoplasmosis. A 65-year-old Korean man presented with multiple pulmonary clumps of tiny nodules in the both lungs. He had been diagnosed 40 years earlier with pulmonary tuberculosis (TB) and a fungus ball had been diagnosed 4 years earlier. He denied any history of overseas travel. The patient visited our hospital with dyspnea, blood-tinged sputum, and weight loss, which had appeared 2 months earlier...
January 8, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29215719/lncrna-snhg1-negatively-regulates-mir-145a-5p-to-enhance-nuak1-expression-and-promote-cancer-cell-metastasis-and-invasion-in-nasopharyngeal-carcinoma
#8
Leqiu Wang, Xiufeng Ma, Lei Yan, Tianxiu Wang, Jingai Wen, Guangxi Mi
Intention: How lncRNA SNHG1 influences the aggressiveness of nasopharyngeal carcinoma cells as well as the underlying mechanism was studied. METHODS: The lncRNA differences were analyzed by GSE12452 gene microarray. The expression of SNHG1, MiR-145-5p and NUAK1 was identified by qRT-PCR and western blot. Transfection was conducted to construct nasopharyngeal carcinoma cells with different expressions of SNHG1 and miR-145-5p. Dual-luciferase reporter assay was performed to explore the relationship between miR-145-5p and NUAK1...
December 7, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29214064/bronchoscopy-for-the-diagnosis-of-peripheral-lung-lesions
#9
REVIEW
Samjot Singh Dhillon, Kassem Harris
Peripheral pulmonary lesions (PPLs) are generally considered as lesions in the peripheral one-third of the lung although a precise definition and radiographic anatomical landmarks separating central and peripheral lesion does not yet exist. The radiographic detection of such lesions has increased significantly with the adoption of lung cancer screening programs. These lesions are not directly visible by regular flexible bronchoscopes as they are usually distal to the lobar and segmental bronchi. Traditionally, depending on location and clinical stage at presentation, these lesions were typically sampled by computerized tomography (CT) guided needle or surgical biopsy although some centers also used ultrasound and fluoroscopy guided percutaneous needle biopsy...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29209425/bilateral-pulmonary-nodules-and-acute-respiratory-failure-in-a-22-year-old-man-with-dyspnoea-and-fever
#10
Giorgio Castellana, Vito Liotino, Maria Rosaria Vulpi, Ina Ali, Lorenzo Marra, Onofrio Resta
Can you diagnose the cause of this man's bilateral pulmonary nodules and acute respiratory failure? http://ow.ly/NfED30dDBzm.
December 2017: Breathe
https://www.readbyqxmd.com/read/29206596/value-of-a-computer-aided-detection-system-based-on-chest-tomosynthesis-imaging-for-the-detection-of-pulmonary-nodules
#11
Yoshitake Yamada, Eisuke Shiomi, Masahiro Hashimoto, Takayuki Abe, Masaki Matsusako, Yukihisa Saida, Kenji Ogawa
Purpose To assess the value of a computer-aided detection (CAD) system for the detection of pulmonary nodules on chest tomosynthesis images. Materials and Methods Fifty patients with and 50 without pulmonary nodules underwent both chest tomosynthesis and multidetector computed tomography (CT) on the same day. Fifteen observers (five interns and residents, five chest radiologists, and five abdominal radiologists) independently evaluated tomosynthesis images of 100 patients for the presence of pulmonary nodules in a blinded and randomized manner, first without CAD, then with the inclusion of CAD marks...
December 4, 2017: Radiology
https://www.readbyqxmd.com/read/29204377/detection-of-pulmonary-nodules-in-low-dose-computed-tomography-using-localized-active-contours-and-shape-features
#12
Zahra Nadealian, Behzad Nazari, Saeid Sadri, Mohammad Momeni
Background: Pulmonary nodules are symptoms of lung cancer. The shape and size of these nodules are used to diagnose lung cancer in computed tomography (CT) images. In the early stages, nodules are very small, and radiologist has to refer to many CT images to diagnose the disease, causing operator mistakes. Image processing algorithms are used as an aid to detect and localize nodules. Methods: In this paper, a novel lung nodules detection scheme is proposed. First, in the preprocessing stage, our algorithm segments two lung lobes to increase processing speed and accuracy...
October 2017: Journal of Medical Signals and Sensors
https://www.readbyqxmd.com/read/29203261/preoperative-computed-tomography-guided-pulmonary-lesion-marking-in-preparation-for-fluoroscopic-wedge-resection-rates-of-success-complications-and-pathology-outcomes
#13
Babatunde Olaiya, Charles A Gilliland, Seth D Force, Felix G Fernandez, Manu S Sancheti, William C Small
PURPOSE: In this study, we describe our experience of lesion marking with fiducial markers (FM) and microcoils (MC) facilitating same-day surgical wedge resection, including success rates, pathology outcomes, and complications. We also explored patient/nodular characteristics associated with developing complications. MATERIALS AND METHODS: An IRB-approved single-institutional retrospective study of 136 patients who had 148 pulmonary nodules was conducted. All patients had CT-guided pulmonary nodule labeling with either FM (121) or MC (15) patients with plan for same-day fluoroscopic-guided wedge resection...
November 6, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/29202877/folate-receptor-targeted-molecular-imaging-improves-identification-of-malignancy-during-pulmonary-resection-a-case-report
#14
Jarrod D Predina, Andrew Newton, Courtney Connolly, Sunil Singhal
BACKGROUND: During minimally invasive pulmonary resection, both limited visualization and tactile feedback can make localization of pulmonary nodules and assessment for synchronous disease challenging. Intraoperative molecular imaging is an emerging technology that can enhance a surgeon's ability to detect cancers at the time of resection. CASE PRESENTATION: In this report, we describe the application of a folate receptor-targeted, near infrared optical contrast agent (OTL38) for the detection of an invasive pulmonary adenocarcinoma...
December 4, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29201875/surgical-treatment-of-synchronous-multiple-neuroendocrine-lung-tumours-case-series-is-more-always-better
#15
Jury Brandolini, Luca Bertolaccini, Alessandro Pardolesi, Piergiorgio Solli
Pulmonary neuroendocrine lung tumours are uncommon neoplasm; the presence of multiple and synchronous lesions is rare, and few case report are described in the literature. We present a case series of three patients without particular symptom and radiologic finding of multiple synchronous pulmonary nodules. All the patients underwent surgical treatment; histopathologic examination revealed typical carcinoid tumours in all three cases (one patient has a synchronous atypical carcinoid). No oncological progressions were observed at follow-up...
November 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29201223/application-of-positron-emission-tomography-computed-tomography-in-the-diagnosis-of-pulmonary-ground-glass-nodules
#16
Lili Hu, Yuanwei Pan, Zhigang Zhou, Jianbo Gao
The aim of the present study was to investigate the value of positron emission tomography-computed tomography (PET-CT) using 18F-fluorodeoxyglucose in the clinical diagnosis of pulmonary ground-glass nodule. In total, 54 patients with pulmonary GGN that were identified by PET-CT examination were selected and confirmed by pathology and clinical diagnosis in hospital between April 2014 and April 2015. The association between PET-CT findings and pathology, and the value of PET-CT were then evaluated. In the 54 patients, solitary pulmonary GGN with a nodule diameter of between 0...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29200086/benefits-of-electromagnetic-navigational-bronchoscopy-for-identifying-pulmonary-nodules-for-robotic-resections
#17
Stevan S Pupovac, Alexander Chaudhry, Vijay A Singh
OBJECTIVE: The ability to localize pulmonary nodules via the robotic thoracic technique can be challenging at times. This is most evident when nodules are small and/or ground glass in nature. Information regarding methods available to localize these difficult nodules, while maintaining a minimally invasive robotic approach, is limited. METHODS: We describe a diagnostic and therapeutic method of combining electromagnetic navigational bronchoscopy with a total minimally invasive robotic approach that identifies these difficult-to-localize pulmonary nodules...
December 1, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29199704/solitary-pulmonary-nodule-evaluation-in-regions-endemic-for-infectious-diseases-do-regional-variations-impact-the-effectiveness-of-fluorodeoxyglucose-positron-emission-tomography-computed-tomography
#18
N C Purandare, C S Pramesh, J P Agarwal, A Agrawal, S Shah, K Prabhash, G Karimundackal, S Jiwnani, S Tandon, V Rangarajan
BACKGROUND: Fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) has become a preferred imaging modality for the evaluation of solitary pulmonary nodule (SPN), particularly in the developed world. Since FDG can concentrate in infective/inflammatory lesions, the diagnostic utility of FDG-PET can be questioned, particularly in regions endemic for infectious decisions. AIM: To evaluate the accuracy of FDG-PET/CT in evaluation of SPNs in a population endemic for infectious disease and to assess if regional variations have an impact on its effectiveness...
January 2017: Indian Journal of Cancer
https://www.readbyqxmd.com/read/29197913/an-alternative-finger-in-robotic-assisted-thoracic-surgery-intraoperative-ultrasound-localization-of-pulmonary-nodules
#19
Zhenyu Zhou, Zhitian Wang, Zhelan Zheng, Jinlin Cao, Chong Zhang, Zhehao He, Wang Lv, Jian Hu
AIM: Robotic-assisted thoracic surgery (RATS) has become a promising treatment for pulmonary neoplasms. During RATS, intraoperative ultrasonography can act as an "alternative finger" to "touch" and locate lesions, especially pulmonary nodules. This study was aimed to investigate the efficacy of intraoperative ultrasonographic localization during da Vinci RATS procedures. MATERIAL AND METHODS: Patients with pulmonary nodules were randomly divided into an Experimental Group and Control Group in which nodules were respectively located using intraoperative ultrasonography or by the surgeon's anatomic knowledge...
November 29, 2017: Medical Ultrasonography
https://www.readbyqxmd.com/read/29196857/pulmonary-subsolid-nodules-value-of-semi-automatic-measurement-in-diagnostic-accuracy-diagnostic-reproducibility-and-nodule-classification-agreement
#20
Hyungjin Kim, Chang Min Park, Eui Jin Hwang, Su Yeon Ahn, Jin Mo Goo
OBJECTIVES: We hypothesized that semi-automatic diameter measurements would improve the accuracy and reproducibility in discriminating preinvasive lesions and minimally invasive adenocarcinomas from invasive pulmonary adenocarcinomas appearing as subsolid nodules (SSNs) and increase the reproducibility in classifying SSNs. METHODS: Two readers independently performed semi-automatic and manual measurements of the diameters of 102 SSNs and their solid portions. Diagnostic performance in predicting invasive adenocarcinoma based on diameters was tested using logistic regression analysis with subsequent receiver operating characteristic curves...
December 1, 2017: European Radiology
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